Digital Commons Network^™

Variation In The Delivery Of Inpatient Orthopaedic Care To Medicaid Beneficiaries Within A Single Metropolitan Region, Christopher J. Dy, Andrew D. Tipping, Katelin B. Nickel, Winston Jiang, Regis J. O'Keefe, Margaret A. Olsen

Open Access Publications

No abstract provided.

Hyper-Activation Of Stat3 Sustains Progression Of Non-Papillary Basal-Type Bladder Cancer Via Fosl1 Regulome, William Vermi, Et Al

Open Access Publications

No abstract provided.

Are Patients With Perforated Peptic Ulcers Who Are Negative For Helicobacter Pylori At A Greater Risk?, Rohit K. Rasane, Christopher B. Horn, Adrian A. Coleoglou Centeno, Nicholas B. Fiore, Marlon Torres Barboza, Qiao Zhang, Kelly M. Bochicchio, Laurie J. Punch, Grant V. Bochicchio, Obeid N. Ilahi

Open Access Publications

No abstract provided.

Targeting Innate Immunity For Tuberculosis Vaccination, Shabaana A. Khader, Maziar Divangahi, Willem Hanekom, Philip C. Hill, Markus Maeurer, Karen W. Makar, Katrin D. Mayer-Barber, Musa M. Mhlanga, Elisa Nemes, Larry S. Schlesinger, Reinout Van Crevel, Ramakrishna Vankalayapati, Ramnik J. Xavier, Mihai G. Netea, On Behalf Of The Bill And Melinda Gates Foundation Collaboration For Tb Vaccine Discovery Innate Immunity Working Group

Open Access Publications

No abstract provided.

Behavioral Predictors Of Autism Recurrence Are Genetically Independent And Influence Social Reciprocity: Evidence That Polygenic Asd Risk Is Mediated By Separable Elements Of Developmental Liability, Alexa Pohl, Warren R. Jones, Natasha Marrus, Yi Zhang, Ami Klin, John N. Constantino

Open Access Publications

No abstract provided.

A Window On The Lung: Molecular Imaging As A Tool To Dissect Pathophysiologic Mechanisms Of Acute Lung Disease, Guido Musch

Open Access Publications

No abstract provided.

Trial Of Sage-217 In Patients With Major Depressive Disorder, Handan Gunduz-Bruce, Christopher Silber, Inder Kaul, Anthony J. Rothschild, Robert Riesenberg, Abdul J. Sankoh, Haihong Li, Robert Lasser, Charles F. Zorumski, David R. Rubinow, Steven M. Paul, Jeffrey Jonas, James J. Doherty, Stephen J. Kanes

Open Access Publications

No abstract provided.

Longitudinal Evaluation Of Cognition After Stroke - A Systematic Scoping Review, Juan Pablo Saa, Tamara Tse, Carolyn Baum, Toby Cumming, Naomi Josman, Miranda Rose, Leeanne Carey

Open Access Publications

BACKGROUND: Cognitive impairment affects up to 80 percent of the stroke population, however, both the available evidence about post-stroke cognition and the measures used to evaluate it longitudinally have not been well described. The aims of this systematic scoping review were: to identify and characterize studies evaluating cognition longitudinally after stroke; to summarize the cognitive instruments used and the domains they target; and to organize cognitive domains assessed using the International Classification of Functioning, Disability and Health (ICF).

METHODS: We used a systematic scoping approach to search for peer-reviewed articles involving adults with stroke that evaluated cognition longitudinally. Screening of …

Tropomyosin Isoforms Differentially Tune Actin Filament Length And Disassembly, Silvia Jansen, Bruce L. Goode

Open Access Publications

No abstract provided.

Cannabinoids, Cannabis, And Cannabis-Based Medicine For Pain Management: A Protocol For An Overview Of Systematic Reviews And A Systematic Review Of Randomised Controlled Trials, Emma Fisher, Christopher Eccleston, Louisa Degenhardt, David P. Finn, Nanna B. Finnerup, Ian Gilron, Simon Haroutounian, Elliot Krane, Andrew S.C. Rice, Michael Rowbotham, Mark Wallace, R. Andrew Moore

Open Access Publications

No abstract provided.

A Protocol For The Systematic Review And Meta-Analysis Of Studies In Which Cannabinoids Were Tested For Antinociceptive Effects In Animal Models Of Pathological Or Injury-Related Persistent Pain, Nadia Soliman, Andrea G. Hohmann, Simon Haroutounian, Kimberley Wever, Andrew S.C. Rice, David P. Finn

Open Access Publications

No abstract provided.

A Promising Bioconjugate Vaccine Against Hypervirulent Klebsiella Pneumoniae, Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. Mckee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding

Open Access Publications

No abstract provided.

Combined Anti-Inflammatory And Neuroprotective Treatments Have The Potential To Impact Disease Phenotypes In Cln3−/− Mice, Marta A. Tarczyluk-Wells, Christoph Salzlechner, Allison R. Najafi, Ming J. Lim, David Smith, Frances M. Platt, Brenda P. Williams, Jonathan D. Cooper

Open Access Publications

No abstract provided.

Genetic Vulnerability To Experiencing Child Maltreatment, Patrizia Pezzoli, Jan Antfolk, Alexander S. Hatoum, Pekka Santtila

Open Access Publications

No abstract provided.

Excitability And Irritability In Preschoolers Predicts Later Psychopathology: The Importance Of Positive And Negative Emotion Dysregulation, Alecia C Vogel, Joshua J Jackson, Deanna M Barch, Rebecca Tillman, Joan L Luby

Open Access Publications

Emotion dysregulation is a risk factor for the development of a variety of psychopathologic outcomes. In children, irritability, or dysregulated negative affect, has been the primary focus, as it predicts later negative outcomes even in very young children. However, dysregulation of positive emotion is increasingly recognized as a contributor to psychopathology. Here we used an exploratory factor analysis and defined four factors of emotion dysregulation: irritability, excitability, sadness, and anhedonia, in the preschool-age psychiatric assessment collected in a sample of 302 children ages 3-5 years enriched for early onset depression. The irritability and excitability factor scores defined in preschoolers predicted …

Current State In Scientific Publishing: Aoa Critical Issues Symposium, Jennifer Moriatis Wolf, Linda J Sandell, Seth S Leopold, Karen L Dodson

Open Access Publications

Orthopaedic surgery has a rich history of publication of the science that supports the practice of our specialty, which dates from 1887. Orthopaedic publishing has evolved since that time, expanding from print to online access, with increasing variation in publication models, including open-access journals and article repositories, and methods of information delivery that include video, data archives, and commentary. This symposium provides an overview of the changes and challenges in the publication of orthopaedic science.

Persistence Of Right Ventricular Dysfunction And Altered Morphometry In Asymptomatic Preterm Infants Through One Year Of Age: Cardiac Phenotype Of Prematurity, Collin T Erickson, Meghna D Patel, Swati Choudhry, Karl Stessy Bisselou, Tim Sekarski, Mary Craft, Ling Li, Afif El Khuffash, Aaron Hamvas, Shelby Kutty, Gautam K Singh, Philip T Levy

Open Access Publications

INTRODUCTION: Prematurity impacts myocardial development and may determine long-term outcomes. The objective of this study was to test the hypothesis that preterm neonates develop right ventricle dysfunction and adaptive remodelling by 32 weeks post-menstrual age that persists through 1 year corrected age.

MATERIALS AND METHODS: A subset of 80 preterm infants (born <29 weeks) was selected retrospectively from a prospectively enrolled cohort and measures of right ventricle systolic function and morphology by two-dimensional echocardiography were assessed at 32 weeks post-menstrual age and at 1 year of corrected age. Comparisons were made to 50 term infants at 1 month and 1 year of age. Sub-analyses were performed in preterm-born infants with bronchopulmonary dysplasia and/or pulmonary hypertension.

RESULT: In both term and preterm infants, right ventricle function and morphology increased over the first year (p < 0.01). The magnitudes of right ventricle function measures were lower in preterm-born infants at each time period (p < 0.01 for all) and right ventricle morphology indices were wider in all preterm infants by 1 year corrected age, irrespective of lung disease. Measures of a) right ventricle function were further decreased and b) morphology increased through 1 year in preterm infants with bronchopulmonary dysplasia and/or pulmonary hypertension (p < 0.01).

CONCLUSION: Preterm infants exhibit abnormal right ventricle performance with remodelling at 32 weeks post-menstrual age that persists through 1 year corrected age, suggesting a less developed intrinsic myocardial function response …

Improvement In Patient-Reported Sleep In Type 2 Diabetes And Prediabetes Participants Receiving A Continuous Care Intervention With Nutritional Ketosis, Morgan J. Siegmann, Shaminie Athinarayanan, Sarah J. Hallberg, Amy L. Mckenzie, Nasir H. Bhanpuri, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Christa J. Van Dort

Open Access Publications

No abstract provided.

The Widely Used Antimicrobial Triclosan Induces High Levels Of Antibiotic Tolerance In Vitro And Reduces Antibiotic Efficacy Up To 100-Fold In Vivo, Corey Westfall, Ana Lidia Flores-Mireles, John Isaac Robinson, Aaron J.L. Lynch, Scott Hultgren, Jeffrey P. Henderson, Petra Anne Levin

Open Access Publications

No abstract provided.

Cluster Analysis To Define Distinct Clinical Phenotypes Among Septic Patients With Bloodstream Infections, Maria Cristina Vazquez Guilamet, Michael Bernauer, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.

Uterine Natural Killer Cells, Dorothy K. Sojka, Liping Yang, Wayne M. Yokoyama

Open Access Publications

No abstract provided.

Advances In Cardiovascular Disease Lipid Research Can Provide Novel Insights Into Mycobacterial Pathogenesis, Shyamala Thirunavukkarasu, Shabaana A. Khader

Open Access Publications

No abstract provided.

General Anesthesia Does Not Have Persistent Effects On Attention In Rodents, Viviane S. Hambrecht-Wiedbusch, Katherine A. Latendresse, Michael S. Avidan, Amanda G. Nelson, Margaret Phyle, Romi E. Ajluni, George A. Mashour

Open Access Publications

No abstract provided.

Incidence Of Acute Kidney Injury In Critically Ill Patients Receiving Vancomycin With Concomitant Piperacillin-Tazobactam, Cefepime, Or Meropenem, Adam M. Blevins, Jennifer N. Lashinsky, Craig Mccammon, Marin Kollef, Scott Micek, Paul Juang

Open Access Publications

No abstract provided.

Sox10 Is A Sensitive Marker For Breast And Salivary Gland Adenoid Cystic Carcinoma: Immunohistochemical Characterization Of Adenoid Cystic Carcinomas, Chen Yang, Lingxin Zhang, Souzan Sanati

Open Access Publications

No abstract provided.

Influence Of Environmental Factors On Social Participation Post-Stroke, Erin L. Foley, Marjorie L. Nicholas, Carolyn M. Baum, Lisa Tabor Connor

Open Access Publications

No abstract provided.

Evidence Of Causal Effect Of Major Depression On Alcohol Dependence: Findings From The Psychiatric Genomics Consortium, Arpana Agrawal, Et Al

Open Access Publications

No abstract provided.

Lithium Chloride Corrects Weakness And Myopathology In A Preclinical Model Of Lgmd1d, Andrew R. Findlay, Rocio Bengoechea, Sara K. Pittman, Tsui-Fen Chou, Heather L. True, Conrad C. Weihl

Open Access Publications

No abstract provided.

Disparities In Health Information-Seeking Behaviors And Fatalistic Views Of Cancer By Sexual Orientation Identity: A Nationally Representative Study Of Adults In The United States, Marvin E. Langston, Lindsay Fuzzell, Marquita W. Lewis-Thames, Saira Khan, Justin X. Moore

Open Access Publications

No abstract provided.

Aminophospholipids Are Signal-Transducing Trem2 Ligands On Apoptotic Cells, Keiro Shirotani, Yuma Hori, Ryohei Yoshizaki, Eri Higuchi, Marco Colonna, Takashi Saito, Shoko Hashimoto, Takashi Saito, Takaomi C. Saido, Nobuhisa Iwata

Open Access Publications

No abstract provided.