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An Evaluation Of Induced Shear Stress On Endothelial Cellular Adhesion Molecules, Edward B. Crabb

Theses and Dissertations

The pathophysiology of atherosclerotic cardiovascular disease (CVD) is highlighted by vascular dysfunction and low-grade vascular inflammation. Furthermore, the site-specific distribution of atherosclerosis throughout the arterial vasculature is primarily determined by local hemodynamic force. Therefore, this dissertation outlines three experiments designed to investigate the role of acute mental and physical (i.e., aerobic exercise), and vascular wall shear stress (SS) on the inflammatory aspects of atherosclerosis. Chapter 2 examines the effect of acute laboratory-induced mental stress on intracellular pro-inflammatory signaling pathways in peripheral blood mononuclear cells. Chapter 3 investigates the impact of acute laboratory-induced mental stress and maximal aerobic exercise on the …

Singing The Landscape: A Meditation On Song, Sound And Community At The Fall Line Of The James River, Sara Bouchard

Theses and Dissertations

I work in the medium of song. A multidisciplinary artist and composer, I make work that is immersive, time-based and often participatory. I interact with landscape and the complexities of American history, bringing into focus local ecologies through the lens of song.

This document accompanies my thesis performance The Sound of a Stone, an immersive exploration of song, language, ecology and locational listening performed in a 4-channel surround format. In the semi-improvised composition, I sample live vocals, mandolin and found natural objects in a combination of roots music traditions and experimental techniques. Utilizing the software Ableton Live to process …

Molecular Pharmacology Of Non-Phyto-Cannabinoid Approaches For Treatment Of Neuropathic Pain, Nadejda A. Blajkevich

Theses and Dissertations

Approximately twenty million people in United States have some form of peripheral neuropathy. It has been shown that the CB₂ cannabinoid receptor is upregulated when there is peripheral nerve injury and activating the CB₂ receptor produces anti-inflammatory effects that translate to a reduction in signs of “neuropathic pain” in animal models. Elevating endogenous cannabinoids by inhibiting degradative enzymes has also been used to reduce neuropathic pain signs in laboratory animal models of pain. We hypothesize that the molecular pharmacology of these two approaches can be leveraged to optimize CB₁/CB₂ activation to improve non-phyto-cannabinoid treatments for …

Therapeutic Targeting Of Relaxin Signaling In Ischemic Heart Disease, Siva Teja Vk Devarakonda

Theses and Dissertations

Ischemic heart disease is characterized by reduced perfusion of oxygenated blood to the myocardium, potentially resulting in infarction upon occlusion of coronary arteries. While prompt reperfusion and advances in in-hospital care have led to a decline in short term mortality, sustained damage to the ventricle, along with reperfusion injury, can lead to progressive deterioration in cardiac function. Limiting the extent of this initial ischemia-reperfusion injury and combating the course of adverse remodeling remains the scope of several preclinical studies geared towards improving cardiac health after MI. To this, relaxin-2 – the peptide hormone that regulates maternal hemodynamic function during pregnancy …

Discriminating Between Technical And Global Competence In Cbt Programs For Youth Anxiety, Jennifer Cecilione

Theses and Dissertations

Therapist competence refers to the skillfulness and responsiveness demonstrated when delivering an intervention and is an important factor to consider in the training and evaluation of therapists. However, competence research is sparse, especially in the youth psychosocial treatment field. A primary discrepancy is whether technical (related to interventions associated with a specific treatment program) and global (general clinical expertise) competence can be measured as distinct dimensions of competence. The goal of the current study was to determine whether instruments of technical (Cognitive-Behavioral Treatment for Anxiety in Youth Competence Scale; CBAY-C; McLeod et al., 2018) and global (Global Therapist Competence Scale …

The Effect Of Quercetin In Periodontal Inflammation, Sara Holden

Theses and Dissertations

Purpose: To determine the effect of Quercetin, a plant based over the counter flavonoid, on periodontal inflammation in a murine model of periodontitis.

Methods: Periodontitis was induced in age and gender matched mice (C57BL/6) using ligatures on the left side of the maxilla and right side was left un-ligated as baseline control. The animals received daily Quercetin gavage or Phosphate Buffered Saline (PBS) starting 5 days prior to ligation which continued throughout the experimental protocol. Micro-computed tomography (micro CT) imaging was used to determine alveolar bone loss. Real Time quantitative (qRT) PCR was used to determine level of gingival tissue …

Abolish Ice . . . And Then What?, Peter L. Markowitz

Articles

In recent years, activists and then politicians began calling for the abolition of the United States’s interior immigration-enforcement agency: U.S. Immigration and Customs Enforcement (ICE). Many people have misinterpreted the call to “Abolish ICE” as merely a spontaneous rhetorical device used to express outrage at the current Administration’s brutal immigration policies. In fact, abolishing ICE is the natural extension of years of thoughtful organizing by a loose coalition of grassroots immigrant-rights groups. These organizations are serious, not only about their literal goal to eliminate the agency, but also about not replacing it with another dedicated agency of immigration police. Accordingly, …

Commercial Speech Protection As Consumer Protection, Felix T. Wu

Articles

The Supreme Court has long said that “the extension of First Amendment protection to commercial speech is justified principally by the value to consumers of the information such speech provides.” In other words, consumers—the recipients or listeners of commercial speech—are the ones the doctrine is meant to protect. In previous work, I explored the implications of taking this view seriously in three contexts: compelled speech, speech among commercial entities, and unwanted marketing. In each of those contexts, adopting a listener-oriented approach leads to the conclusion that many forms of commercial speech regulation should receive far less First Amendment scrutiny than …

The “New” District Court Activism In Criminal Justice Reform, Jessica A. Roth

Articles

Historically, the debate over the judicial role has centered on the constitutional and administrative law decisions of the United States Supreme Court, with an occasional glance at the Federal Courts of Appeals. It has, moreover, been concerned solely with the “in-court” behavior of Article III appellate judges as they carry out their power and duty “to say what the law is” in the context of resolving “cases and controversies.” This Article seeks to deepen the discussion of the appropriate role of Article III judges by broadening it to trial, as well as appellate, judges; and by distinguishing between an Article …

Jurisliterature And Transgression, Peter Goodrich

Articles

The jurisliterary profession is the curious enterprise of writing, as a jurist, about law. Many seek to escape into literature, philosophy, critique, psychoanalysis, the couch, but then, in the main, they have abandoned law. Those that persist, who remain jurists, have the propensity to transgress the boundaries of the juridical, the strictures of abstraction and disembodiment, so as to generate accounts of legal sensibility, so as to manifest the polyglottal and visceral potential of transforming the juridical bubble into that most ethical of realms, the poetics of desire. Jurisliterary transgression, at its strongest, returns the materiality of imagination to the …

Assessment Of The Localized Flow And Tidal Energy Conversion System At An Estuarine Bridge, Kaelin Chancey

Master's Theses and Capstones

As part of the Living Bridge Project, a cross-flow tidal turbine and estuarine instrumentation have been deployed in the Piscataqua River at the Memorial Bridge connecting Portsmouth, New Hampshire and Kittery, Maine. At the turbine location, flow measurements were taken and are compared to a previous, nearby tidal energy resource assessment. A higher mean kinetic power density was observed for the most recent acoustic Doppler current profiler (ADCP) survey conducted. Acoustic Doppler velocimeter (ADV) data was collected in order to study the spatial distribution of the currents around the turbine. Differences along the turbine deployment platform were determined to be …

How U.S. Family Law Might Deal With Spousal Relationships Of Three (Or More) People, Edward D. Stein

Articles

For much of this nation's history, the vast majority of people have believed that being married to more than one person at the same time is deeply problematic. Further, polygamous marriage has never been legal in the United States. Despite this, some people have been in plural or group relationships and some of these people have wished to gain legal recognition for these relationships. The arguments for recognizing such relationships are persuasive, but the prospects for legalization of polygamous marriage seem slim in the near future. This Article offers a suggestion of how the law of domestic relations might deal …

Fewell-Caldwell-Carothers Family Papers - Accession 254, Fewell Family, Caldwell Family, Carothers Family

Manuscript Collection

The collection consists of genealogical data, correspondence, speeches and essays, sermons, Civil War and World War I papers and memorabilia, diaries, legal and financial papers, photographs, newspaper clippings, and various papers relating to the Fewell, Caldwell, and Carothers families. The collection also contains records relating to Winthrop College, Winthrop Training School, and Salem College, Winston-Salem, N.C. Bound Volumes in the collection are scrapbooks realign to the college career of Eva M. Fewell (Carothers), and the civic and business careers of Benjamin M. Fewell and Erwin Carothers. Related by marriage, the Fewell and Carothers families have a long history of business …

York County League Of Women Voters - Accession 161, League Of Women Voters, York County

Manuscript Collection

The York County League of Women’s Voters is a political organization active in encouraging citizen participation in the electoral process and the government in general. The collection consists of bylaws, constitutions, correspondence, membership lists, newsletters, publications, program notes, minutes, annual reports, model cities information, project information, and questionnaires concerning the creation, activities and early history of the League.

The Unconstitutional Tampon Tax, Bridget J. Crawford, Emily Gold Waldman

University of Richmond Law Review

Thirty-five states impose a sales tax on menstrual hygiene products, while products like spermicidal condoms and erectile dysfunction medications are tax-free. This sales tax—commonly called the “tampon tax”—represents an expense that girls and women must bear on top of the cost of biologically necessary items that they need in order to attend school, work, and otherwise participate in public life. This article explores the constitutionality of the tampon tax and argues that it is an impermissible form of gender discrimination under the Equal Protection Clause. First, menstrual hygiene products are a unique proxy for female sex, and therefore any disadvantageous …

On Opioids And Erisa: The Urgent Case For A Federal Ban On Discretionary Clauses, Katherine T. Vukadin

University of Richmond Law Review

The American opioid epidemic cuts across all social divisions, touching the employed and unemployed. Those with private health insurance are one of the fastest-growing affected groups, but this group struggles most to get care. Despite their insured status, the privately-insured received treatment at half the rate of those with Medicaid and at even lower rates than the uninsured. This article focuses on a significant barrier to treatment for those in employer sponsored benefit plans: the discretionary clause. A discretionary clause grants the decision maker broad latitude and ensures that any federal court review is deferential. Claims processing in such a …

Natural Disaster, Crime, And Narratives Of Disorder: The 1861 Mendoza Earthquake And Argentina’S Ruptured Social And Political Faults, Quinn P. Dauer

Midwest Social Sciences Journal

Social scientists studying natural disasters have generally found an absence of panic, a decrease in crime, and survivors working together to find basic necessities in the days and weeks after a catastrophe. By contrast, political and military authorities implement measures such as martial law to prevent chaos and lawlessness threatening private property. The media amplifies narratives of disorder, creating the perception of uncontrolled masses wantonly committing crimes in a disaster’s aftermath. Historians study natural disasters to view political, social, economic, and cultural structures stripped of their everyday veneer. The 1861 earthquake that destroyed the provincial capital of Mendoza in western …

Antidiscrimination Ordinances In Northwest Indiana: An Event-History Analysis Of Municipal Policies Since 1992, James Paul Old, Kimberly Palmer Fields

Midwest Social Sciences Journal

In recent years, municipalities throughout Indiana have passed antidiscrimination ordinances that protect the rights of individuals who belong to racial, ethnic, or sexual minorities. Political scientists have proposed competing theories of policy-adoption processes that suggest a number of internal factors (such as socioeconomic characteristics, governmental capacity, or issue salience) or external factors (such as mandates/incentives from higher-level governments or influence from neighboring communities) as predictors of policy adoption; however, most existing studies focus on state-level processes, and those that focus on municipalities consider only large cities in different states. To more clearly distinguish between state-level effects and local effects, this …

“We Are A Very Happy Family”: 19th-Century Familial Power Dynamics, Stella A. Ress

Midwest Social Sciences Journal

This article examines the roles of family members in the mid-19th century in America, using the Willard family as a case study. Ultimately, this thick description of the Willard family demonstrates that power within the family structure was neither intrinsic nor static; moreover, one person did not control the family and its decisions at all times. Instead, each family member, depending upon circumstances, situations, and his or her own nature, negotiated and laid claim to power through various sources of authority. Josiah Willard’s authority stemmed from his role as father and husband; society crowned him king of the household, and …

Measures Of Challenging And Excitatory Parenting Behavior As Predictors Of Later Child Self-Regulation, Zachary Havlin

Midwest Social Sciences Journal

Challenging and excitatory parenting behaviors play an important role in children’s development, particularly in regard to the development of selfregulation; however, no well-established measures of parent-child interactions exist that record such behaviors. In the current study, I compare two recently developed coding systems that intend to address this issue: the Risky Interaction Support and Challenging (RISC) and Marbach coding systems. A subset of videos from the New Parents Project (NPP) data set at 12 and 18 months was coded using both scales, then a factor analysis was conducted for each scale. Regressions were conducted to look at the predictive power …

Reliability And Relationship Of The Fear-Avoidance Beliefs Questionnaire With The Shoulder Pain And Disability Index And Numeric Pain Rating Scale In Patients With Shoulder Pain, Sean P. Riley, Vincent Tafuto, Mark Cote, Jean-Michel Brismée, Alexis Wright, Chad Cook

Physical Therapy Faculty Publications

Purpose: The purpose of this study was to determine: 1) the test–retest reliability of Fear-Avoidance Beliefs Questionnaire (FABQ) Work (FABQW) subscale, FABQ Physical Activity (FABQPA) subscale, Shoulder Pain and Disability Index (SPADI) Pain subscale, SPADI Disability subscale, and Numeric Pain Rating scale (NPRS); and 2) the relationship between the FABQPA, FABQW, SPADI pain, SPADI disability, and NPRS after 4 weeks of pragmatically applied physical therapy (PT) in patients with shoulder pain. Design: Prospective, single-group observational design. Methods: Data were collected at initial evaluation, the first follow-up visit prior to the initiation of treatment, and after 4 weeks of treatment. …

Security Analysis Of The Internet Of Things Using Digital Forensic And Penetration Testing Tools, Olajide Ojagbule

College of Graduate Studies: Theses & Dissertations

We exist in a universe where everything is related to the internet or each other like smart TVs, smart telephones, smart thermostat, cars and more. Internet of Things has become one of the most talked about technologies across the world and its applications range from the control of home appliances in a smart home to the control of machines on the production floor of an industry that requires less human intervention in performing basic daily tasks. Internet of Things has rapidly developed without adequate attention given to the security and privacy goals involved in its design and implementation. This document …

The Impact Of Stress On Resilience: Examining The Moderated Effects Of A Savoring Intervention, Hannah L. Newman

College of Graduate Studies: Theses & Dissertations

Resilience is characterized by the ability to bounce back from stress (Bonanno, 2004; Ong et al., 2006; Smith et al., 2008). Research suggests resilience is a personal resource that helps individuals effectively cope with stress and provides protection from negative outcomes (Loh, Schutte, & Thorsteinsson, 2013). Exposure to stress is a prerequisite to building resilience across many different contexts (Graber et al., 2015; Hennessey & Levine, 1979; Rutter, 2006). Interestingly, a high accumulation of stress detracts from an individual’s abilities to build resilience (Ong et al., 2006; Tuguade & Frederickson, 2007). However, it is unknown what types of interventions explicitly …

Mental Toughness As A Predictor For Pre-Season Depression And Anxiety Symptoms, And Changes Over The Course Of An Athletic Season, Colleen J. Bohannan

College of Graduate Studies: Theses & Dissertations

Background: Mental toughness (MT) has been considered necessary for individuals to be successful in the athletic setting. A connection has been theorized between MT and mental health. Purpose: ­­­­­­­­­­­­­­­­­­­­­­The purpose was to investigate if MT could be utilized as a predictor of the presence of depression and/or anxiety symptoms. This study also explored if MT, and depression/anxiety symptoms change over the course of a competitive season. Methods: 43 individuals (19.42 ± 1.26 years) participating in a fall team sport from the same Division I University participated in the study. Data was captured during pre-season, high stakes, and end of season, …

Ego Depletion: Buffering Through Touch, Victoria E. Forgea

College of Graduate Studies: Theses & Dissertations

Ego depletion theory states that self-control is tied to a limited resource and diminishes after repeated exertions; consequently, the current study sought to examine how to replenish self-control through touch. Due to the positive outcomes of touch, we expected touch to allow participants to persist longer on a geometric tracing puzzle task after becoming ego depleted. The current study implemented measures widely used in the ego depletion literature, and the experimenter implemented two brief touches to examine the effects of touch in the domain of self-control. We found that participants who received touch persisted significantly longer on the geometric tracing …

Effects Of Four Years Of Collegiate Sport Participation On Non-Contact, Contact, And Collision Athletes During Gait, Kristen L. Neitz

College of Graduate Studies: Theses & Dissertations

College athletes are often exposed to many training sessions, stresses, and injuries throughout their collegiate career. They often experience pain, stiffness, swelling, reduced range of motion and many other feelings following participation.. Much research has focused on the acute effects of collegiate athletics, but the long term effect has not been well studied. Sports are often divided into groups based on the nature of play; the three main groups are non-contact, contact, and collision sports. Differences have not been observed between the three sport groups and their ability to complete activities of daily living such as walking following four years …

"Solace For [The] Very Soul": The Role Of Trees Within The American Short-Story Cycle, Breanna B. Harris

College of Graduate Studies: Theses & Dissertations

Over the last couple of centuries, the American short-story genre became characterized by its observations of life and human nature—specifically by using scenes of nature to highlight characters’ development and the underlying theme. While much critical attention has been given to the role of nature in the American short-story cycle, very little consideration has been given to the purpose of trees and their specific breeds within the genre. This project focuses on three distinct pedagogical approaches to analyzing trees in three short-story cycles. Deleuze and Guattari’s theory of the rhizome and Freud’s theory of dream-thoughts are applied to Mary Wilkins …

The Relationship Between The Nfl Scouting Combine And Game Performance Over A Five Year Period, Jordan Cook

College of Graduate Studies: Theses & Dissertations

The National Football League (NFL) Scouting Combine offers good face validity however, there has been doubt on the ability of the NFL Combine to predict future success of athletes in relation to in game performance (i.e., predictive validity). This study analyzed the NFL Combine data of 1537 college football players who participated in the Combine between 2013 and 2017 and their subsequent year’s performance in the NFL. The measures used from the Combine were the six different measures of athletic performance; 40-yard dash, vertical jump (VJ), broad jump, shuttle run (PRO), 3-cone drill, and bench press (BP). The measure of …

Physiological Profile Of Rural Structural Firefighters In Southeast Georgia, Emily Langford

College of Graduate Studies: Theses & Dissertations

Many occupational tasks associated with firefighting require a great deal of cardiovascular and muscular demands. However, it is often noted that firefighters throughout the country are not meeting the fitness levels required of the profession. As a result, the proportion of on-duty injury and cardiac death is greater than the general population or similar service professions. Purpose: The purpose of this study was to provide an extensive physiological profile of rural firefighters in southeast Georgia. Methods: Forty firefighters from one department in southeast Georgia underwent a comprehensive health screening, measuring anthropometrics (i.e., height, weight, waist and hip circumference), body …

Analysis Of Human Emf Exposure In 5g Cellular Systems, Imtiaz Nasim

College of Graduate Studies: Theses & Dissertations

Increasing concerns of communications at a frequency spectrum higher than 6 GHz have gained international alarm that suggests more research is needed before it is deployed successfully. In this context, in the first part of this thesis, we investigated the human electromagnetic field (EMF) exposure in indoor and outdoor environments from fifth-generation (5G) downlink communications and compared its impacts with the present cellular technologies considering the features that the 5G will likely adopt. The second part focuses on mitigation of human exposure for both indoor and outdoor environments with two different methods adopted. Our simulation results suggest that while the …