Digital Commons Network^™

Defining A Recovery-Oriented Cascade Of Care For Opioid Use Disorder: A Community-Driven, Statewide Cross-Sectional Assessment, Jesse L. Yedinak, C. Goedel, Kimberly Paull, Rebecca Lebeau, Maxwell S. Krieger, Cheyenne Thompson, Ashley L. Buchanan, Tom Coderre, Rebecca Boss, Josiah D. Rich, Brandon D. L. Marshall

Pharmacy Practice and Clinical Research Faculty Publications

Background

In light of the accelerating and rapidly evolving overdose crisis in the United States (US), new strategies are needed to address the epidemic and to efficiently engage and retain individuals in care for opioid use disorder (OUD). Moreover, there is an increasing need for novel approaches to using health data to identify gaps in the cascade of care for persons with OUD.

Methods and findings

Between June 2018 and May 2019, we engaged a diverse stakeholder group (including directors of statewide health and social service agencies) to develop a statewide, patient-centered cascade of care for OUD for Rhode Island, …

Unh Research Confirms Migration Is Biggest Driver Of Population Change In N.H., Erika Mantz

Media Relations

No abstract provided.

Continuous Glucose Monitoring Based On Remote Sensing Of Variations Of Parameters Of A Sic Implanted Antenna, Fabiola Araujo Cespedes, Stephen E. Saddow, Christopher Leroy Frewin, Erdem Topsakal

USF Patents

A passive sensing continuous glucose monitoring system and method of use thereof. The system includes a passive antenna formed of biocompatible silicon carbide (SiC), modeled to a desired frequency, which is permanently implanted subcutaneously. The system further includes an external-to-the-body transmitting antenna to detect changes in the blood glucose level by sending a radio signal at the frequency of the implanted passive antenna into the body. This signal is received and reflected by the passive antenna, and the reflected signal is then received at an external-to-the-body receiving antenna. Changes in the glucose level lead to modifications in the signal and …

Daily Eastern News: November 19, 2019, Eastern Illinois University

November

No abstract provided.

Instructional Focus And Task Load In Performance Of A Fine Motor Skill, Adam Linden

Honors Theses

No abstract provided.

Trends In Prices Of Insulin Marketed In The Us, Hana Althobaiti

Pharmaceutical Sciences (MS) Theses

INTRODUCTION: Diabetes mellitus is one of the most prevalent and costly chronic diseases in the United States (US). The healthcare and drug cost of diabetes has risen steadily and the increase in patients’ out-of-pocket drug expenditures are associated with a reduction in treatment adherence. The objectives of this study were to assess trends in insulin products prices in the period January 1983-July 2019, and to compare the price, acquisition costs and reimbursement amount of insulins available in the US.

DATA AND METHODS: Data of insulin products marketed in the US during the period January 1983-July 2019 was derived from the …

First-Year Students Offered Support Needed To Succeed, Edwin B. Smith

University of Mississippi News

UM Student Success Coaching provides tutoring, mentoring and more

Role Of Probiotics In Non-Alcoholic Fatty Liver Disease: Does Gut Microbiota Matter?, Chencheng Xie, Dina Halegoua-De Marzio

Division of Gastroenterology and Hepatology Faculty Papers

Non-alcoholic fatty liver disease (NAFLD) is the hepatic consequence of metabolic syndrome, which often also includes obesity, diabetes, and dyslipidemia. The connection between gut microbiota (GM) and NAFLD has attracted significant attention in recent years. Data has shown that GM affects hepatic lipid metabolism and influences the balance between pro/anti-inflammatory effectors in the liver. Although studies reveal the association between GM dysbiosis and NAFLD, decoding the mechanisms of gut dysbiosis resulting in NAFLD remains challenging. The potential pathophysiology that links GM dysbiosis to NAFLD can be summarized as: (1) disrupting the balance between energy harvest and expenditure, (2) promoting hepatic …

Some Preliminary Observations With The Native Health Database, Jonathan Pringle

Native Health Database project records

Presentation about the NHD for the ATALM annual meeting.

Opening Doors, Meghan Murphy

UNH Today Archive

No abstract provided.

Robinson Named To National Counseling Bod, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Watcher Of The Skies, Benjamin Gleisser

UNH Today Archive

No abstract provided.

We Need To Change The Language We Use To Describe Individuals With Substance Use Issues, Austin Mcneill Brown

Population Health Research Brief Series

People with substance use disorders (SUDs) are highly stigmatized worldwide. This research brief describes the results from several studies on unconscious bias and negative language used to describe individuals with SUDs.

Sirtuin 3 Deficiency Does Not Impede Digit Regeneration In Mice, Emily Busse, Jennifer Simkin, Luis Marrero, Kennon Stewart, Regina Brunauer, Ken Muneoka, Anyonya Guntur, Michelle Lacey, Mimi Sammarco

School of Medicine Faculty Publications

The mitochondrial deacetylase sirtuin 3 (SIRT3) is thought to be one of the main contributors to metabolic flexibility-promoting mitochondrial energy production and maintaining homeostasis. In bone, metabolic profiles are tightly regulated and the loss of SIRT3 has deleterious effects on bone volume in vivo and on osteoblast differentiation in vitro. Despite the prominent role of this protein in bone stem cell proliferation, metabolic activity, and differentiation, the importance of SIRT3 for regeneration after bone injury has never been reported. We show here, using the mouse digit amputation model, that SIRT3 deficiency has no impact on the regenerative capacity and architecture …

The Current Volume 30 : Issue 13, Nova Southeastern University

Student Newspapers

No abstract provided.

Chronic Obstructive Pulmonary Disease (Copd) And The Nutrition Care Process, Emily Anderson

Nutrition & Dietetics Student Publications

This paper displays the role that Registered Dietitians can play in the care of patients with COPD and it’s related side effects. A registered dietitian nutritionist’s (RDNs) job is to ensure adequate care through thorough assessment, diagnosis, treatment and evaluation, otherwise known as the Nutrition Care Process (ADIME-NCP). Through the story of my uncle and his journey with COPD you are able to understand the struggles this chronic disease can have and how RDN’s play a role in their care.

November 19, 2019, The Dakota Student

The Dakota Student

No abstract provided.

Practitioner's Guide To Small Unmanned Aerial Systems For Bridge Inspection, Sattar Dorafshan, Robert J. Thomas, Calvin Coopmans, Marc Maguire

Civil Engineering Faculty Publications

Small unmanned aerial system(s) (sUAS) are rapidly emerging as a practical means of performing bridge inspections. Under the right condition, sUAS assisted inspections can be safer, faster, and less costly than manned inspections. Many Departments of Transportation in the United States are in the early stages of adopting this emerging technology. However, definitive guidelines for the selection of equipment for various types of bridge inspections or for the possible challenges during sUAS assisted inspections are absent. Given the large investments of time and capital associated with deploying a sUAS assisted bridge inspection program, a synthesis of authors experiences will be …

Biological And Practical Implications Of Genome-Wide Association Study Of Schizophrenia Using Bayesian Variable Selection, Benazir Rowe, Xiangning Chen, Zuoheng Wang, Jingchun Chen, Amei Amei

School of Medicine Faculty Research

Genome-wide association studies (GWAS) have identified over 100 loci associated with schizophrenia. Most of these studies test genetic variants for association one at a time. In this study, we performed GWAS of the molecular genetics of schizophrenia (MGS) dataset with 5334 subjects using multivariate Bayesian variable selection (BVS) method Posterior Inference via Model Averaging and Subset Selection (piMASS) and compared our results with the previous univariate analysis of the MGS dataset. We showed that piMASS can improve the power of detecting schizophrenia-associated SNPs, potentially leading to new discoveries from existing data without increasing the sample size. We tested SNPs in …

Independent - Nov. 19, 2019, Frannie Mendoza

The Independent (1988-present)

No abstract provided.

Identification Of Novel Adenylyl Cyclase 5 (Ac5) Signaling Networks In D1 And D2 Medium Spiny Neurons Using Bimolecular Fluorescence Complementation Screening, Trevor B. Doyle, Brian S. Muntean, Karin F. Ejendal, Michael P. Hayes, Monica Soto-Velasquez, Kirill A. Martemyanov, Carmen W. Dessauer, Chang-Deng Hu, Val J. Watts

Purdue University Libraries Open Access Publishing Fund

Adenylyl cyclase type 5 (AC5), as the principal isoform expressed in striatal medium spiny neurons (MSNs), is essential for the integration of both stimulatory and inhibitory midbrain signals that initiate from dopaminergic G protein-coupled receptor (GPCR) activation. The spatial and temporal control of cAMP signaling is dependent upon the composition of local regulatory protein networks. However, there is little understanding of how adenylyl cyclase protein interaction networks adapt to the multifarious pressures of integrating acute versus chronic and inhibitory vs. stimulatory receptor signaling in striatal MSNs. Here, we presented the development of a novel bimolecular fluorescence complementation (BiFC)-based protein-protein interaction …

Minutes From November 19 2019, University Senate

University Senate Minutes

Minutes from November 19 2019 University Senate Meeting

Keeping Allergen Names Clear And Defined, Sanny K. Chan, Anna Pomés, Christiane Hilger, Janet M. Davies, Geoffrey Mueller, Annette Kuehn, Andreas L. Lopata, Gabriele Gadermaier, Marianne Van Hage, Monika Raulf, Richard E. Goodman

Department of Food Science and Technology: Faculty Publications

The World Health Organization/International Union of Immunological Societies (WHO/IUIS) Allergen Nomenclature Sub-Committee was established in 1986 by leading allergists to standardize names given to proteins that cause IgE-mediated reactions in humans. The Sub-Committee’s objective is to assign unique names to allergens based on a critical analysis of confidentially submitted biochemical and clinical data from researchers, often prior to publication to preserve consistency. The Sub-Committee maintains and revises the database as the understanding of allergens evolves. This report summarizes recent developments that led to updates in classification of cockroach group 1 and 5 allergens to animal as well as environmental and …

Volume 117, Number 4 - Tuesday, November 19, 2019, Saint Mary's College Of California

The Collegian

No abstract provided.

A Prospective Clinical Study On Implant Impression Accuracy, Motaz Osman, Hassan Ziada, Ahmed Suliman, Neamat Hassan Abubakr

Dental Medicine Faculty Research

Background An accurate impression is crucial to the long-term success of dental implants. This investigation evaluated the accuracy of the open and closed implant impression techniques in partially edentulous patients who received two adjacent implants. Material and methods Forty patients received Osstem Implants (Osstem Implant System, Seoul, Korea). Two impressions were made for each patient, one using an open tray and a second with a closed tray technique. The horizontal distances between two impression copings were measured and compared to similar measurements on the master casts. Also, under a stereomicroscope (AmScop14370, Myford Road, #150, Irvine, CA 92606 USA) at a …

Open Access: Could Defeat Be Snatched From The Jaws Of Victory?, Richard Poynder

Copyright, Fair Use, Scholarly Communication, etc.

When news broke early in 2019 that the University of California had walked away from licensing negotiations with the world’s largest scholarly publisher (Elsevier), a wave of triumphalism spread through the OA Twittersphere. The talks had collapsed because of Elsevier’s failure to offer UC what it demanded: a new-style Big Deal in which the university got access to all of Elsevier’s paywalled content plus OA publishing rights for all UC authors – what UC refers to as a “Read and Publish” agreement. In addition, UC wanted Elsevier to provide this at a reduced cost.1 Given its size and influence, UC’s …

The Impact Of Systemic Precision Medicine And Immunotherapy Treatments On Brain Metastases, Rowland H. Han, Gavin P. Dunn, Milan G. Chheda, Albert H. Kim

Open Access Publications

Metastases from melanoma, lung and breast cancer are among the most common causes of intracranial malignancy. Standard of care for brain metastases include a combination of surgical resection, stereotactic radiosurgery, and whole-brain radiation. However, evidence continues to accumulate regarding the efficacy of molecularly-targeted systemic treatments and immunotherapy. For non-small cell lung cancer (NSCLC), numerous clinical trials have demonstrated intracranial activity for inhibitors of EGFR and ALK. Patients with melanoma brain metastases may benefit from systemic therapy using BRAF-inhibitors with and without trametinib. Several targeted options are available for breast cancer brain metastases that overexpress HER2, although agents with intracranial activity …

The Ies-R Remains A Core Outcome Measure For Ptsd In Critical Illness Survivorship Research, Megan M. Hosey, O. Joseph Bienvenu, Victor D. Dinglas, Alison E. Turnbull, Ann M. Parker, Ramona O. Hopkins, Karin J. Neufeld, Dale M. Needham

Faculty Publications

To the Editor: In response to Dr. Umberger’s comments on the Impact of Event Scale-Revised (IES-R) and the abbreviated 6-item IES (IES-6), we offer guidance about assessing post-traumatic stress disorder (PTSD) symptoms as part of the existing National Institutes of Health-funded core outcome measurement set (COMS) for clinical research in acute respiratory failure (ARF) survivors

Using Smartwatches For Fitness And Health Monitoring: The Utaut2 Combined With Threat Appraisal As Moderators, Phaik Khee Beh, Yuvaraj Ganesan, Mohammad Iranmanesh, Behzad Foroughi

Research outputs 2014 to 2021

Recent advancements in smartwatch technology have led to several applications in continuous fitness and health monitoring. Considering the benefits of smartwatches, their low level of usage for fitness and health monitoring purposes, and the limited understanding of determinants of their usage, this study advances the body of knowledge by developing an innovative and comprehensive research model that integrates the extended unified theory of acceptance and use of technology (UTAUT2) with perceived vulnerability and perceived severity as moderators. The model was tested using partial least squares (PLS), in a quantitative study with data from 271 respondents from Malaysia. The results showed …

Non-Invasive Methods For Measuring And Monitoring Stress Physiology In Imperiled Amphibians, Edward J. Narayan, Zachery R. Forsburg, Drew R. Davis, Caitlin R. Gabor

School of Earth, Environmental, & Marine Sciences Faculty Publications

Global climate change is negatively impacting global biodiversity and ectothermic vertebrates, with amphibians being the most imperiled vertebrate taxa. Increased mean global atmospheric temperatures, high rates of habitat degradation, and exposure to infectious diseases, such as chytridiomycosis, have contributed to population declines and extinctions of rare and endangered amphibian species. Field-based monitoring of physiological endocrine traits can help determine the sub-lethal effects of environmental stressors and provide early alerts when populations are chronically stressed. Recent advances in amphibian stress endocrinology include the development and use of non-invasive methods to quantify the glucocorticoid, or stress biomarker, corticosterone. Non-invasive methods, such as …