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Sensory Primary Cilium Is A Distinct Signaling Compartment, Rinzhin Tshering Sherpa

Pharmaceutical Sciences (PhD) Dissertations

The primary cilium is a solitary cellular organelle that protrudes from the apical cell membrane. Findings on cilia-dependent mechanosenstation have shown that the primary cilium acts as a transducer of fluid-shear stress into intracellular signaling. Over recent years, studies in primary cilia have intensified after determining a causal relationship between dysfunctional primary cilia and cystic diseases. Along with its mechanosensory function, the primary cilium houses a variety of receptors, ion channels and transporter proteins. Studies in cilia biology have shown that primary cilia are coordinators of signaling pathways such as Hedgehog (Hh), Wnt, and platelet-derived growth factor (PDGF) pathways during …

Tremblings, August 2019, Western Aspen Alliance

Tremblings

Climate's Cascading Effects In Aspen Systems

Thomas E. Martin

Aspen is an unusually important resource for wildlife. It is associated with high primary productivity providing abundant resources that support high biodiversity. It is especially important because its soft inner core that often contracts heart rot provides a favored resource for cavity-nesting organisms. The abundance and diversity of cavity-nesting species using aspen stands exceeds any other habitat type. As a result, maintenance and expansion of aspen stands is important for conservation of biodiversity.

The Roles Of Long Noncoding Rnas In Inflammation And Immune Responses, Monira Obaid

Chemistry & Biochemistry Dissertations - Archive

Inflammation is an immune response that protects the human body from infection, illness, or injury. The inflammatory response causes the activation of immune cells, such as leukocyte subsets (i.e., monocytes, macrophages, dendritic cells, neutrophils, eosinophils and others), T cells, and B cells, and induces production of inflammatory mediators such as cytokines, chemokines, and antibodies to fight against injury or infection. Uncontrolled and continued inflammation drives the development of many human diseases, including metabolic diseases, obesity, diabetes, autoimmune disorders, neurological disorder and cancer. Indeed, the signaling process associated with inflammation and immune response is very complex. Our understanding of inflammation and …

Development Of Innovative Theranostic Platforms For Biomedical Applications, Min Kyung Khang

Chemistry & Biochemistry Dissertations - Archive

Modern technologies have been successfully identifying patient’s disease-related genetic information and developing effective drugs continuously. The discovery of molecular biomarkers paves new roads for potential individualized therapeutic applications; thus far, the call for a more development of advanced targeting/delivery platforms is highly required in the bioengineering field. Unfortunately, bioengineered targeting platforms for drug delivery at the right place, right dosage and right time have still remained in the developmental stages. To develop innovative nanosystems for various biomedical applications, polymer chemistry and click chemistry are needed to improve the function of the nanosystems. My dissertation research is based upon a unique …

Color Lightness And Inter-Item Hierarchy: When People Associate Darker Colors With Higher Hierarchical Items, Myungjin Chung

Marketing Dissertations - Archive

While a rich collection of literature demonstrates the influence of packaging color on consumer decision making, little is known about how packaging color affects consumer behavior for bundled products. Bundled products are defined as two or more items in a single package for a special price. Often bundles consist of items with varying hierarchy: a higher-hierarchical product paired with a lower-hierarchical product (e.g., a fabric detergent and a fabric softener). I argue and show that there is a universal association between color lightness of the products’ packages and the perceived inter-item hierarchy, with darker packaging signifying a higher hierarchical product …

User Syndication Using Speech Rhythm, Faisal Z H Alnahhas

Civil Engineering Theses - Archive

In recent years we have seen a variety of approaches to increase security on computers and mobile devices including fingerprint, and facial recognition. Such techniques while effective are very expensive. Voice biometrics, specifically speech rhythm, is a method that has been drawing attention and growing in recent years. Unlike other methods, it requires little to no additional hardware installed on a device for it to work accurately. Speech rhythm utilizes the device's built-in microphone, and analyzes speakers based on features of their speech. In this work we leverage the existing hardware and simply add an efficient layer of software to …

A Qualitative Investigation Of The Andragogical Teaching Methods Used In Adult Group Piano/Organ Instruction, Deborah Timpone Curran

Dissertations

This qualitative case study explored adult keyboard (piano/organ) students in a group environment at a piano/organ store in the Midwest United States. Included in the study was a Level 1 Piano class, a Level 2 Piano class, and one Seniors’ Organ class. The researcher explored the use of andragogical principles in the group keyboard classes based upon the programming and instruction, especially in connection with Knowles’ six assumptions and eight processes of andragogy. In addition, the researcher also focused on the presence of trust in the relationships between instructor(s) and student participants, or the lack thereof. The use of Henschke’s …

Effect Of Caffeine Supplementation On Vertical Jump Performance, Heart Rate Variability, And Electromyography, Collin T. Garner

Masters Theses

Research into caffeine’s ability to improve anaerobic performance is inconclusive. Eleven anaerobically trained individuals (mean age: 23.45 ± 1.51 years) participated in this study. Assessments of resting heart rate variability (HRV), exercise heart rate variability, surface electromyography (sEMG), static vertical jump (SJ), and countermovement vertical jump (CMJ) were conducted before and after administration of placebo and caffeinated treatments. Three trials of each vertical jump technique were performed before and after treatment administration. A 60-minute absorption period was utilized for absorption of the treatment following its ingestion. All participants performed testing on two separate occasions, once under the placebo condition and …

An Explainable Recommender System Based On Semantically-Aware Matrix Factorization., Mohammed Sanad Alshammari

Electronic Theses and Dissertations

Collaborative Filtering techniques provide the ability to handle big and sparse data to predict the ratings for unseen items with high accuracy. Matrix factorization is an accurate collaborative filtering method used to predict user preferences. However, it is a black box system that recommends items to users without being able to explain why. This is due to the type of information these systems use to build models. Although rich in information, user ratings do not adequately satisfy the need for explanation in certain domains. White box systems, in contrast, can, by nature, easily generate explanations. However, their predictions are less …

Character Arcs: Mapping Creative Writers' Trajectories Into The Composition Classroom., Jon Udelson

Electronic Theses and Dissertations

This dissertation develops a theoretical and empirical approach to the study of professional creative writers and teachers. Specifically, it examines how these writers developed their knowledge of creative writing and writing pedagogy and how that knowledge informs their work as instructors of composition. Despite the common practice across writing programs of hiring formally-trained creative writers (M.A., M.F.A, Ph.D.) to teach first-year composition and related courses, little scholarship in the field of rhetoric and composition or writing studies more broadly specifically focuses on the disciplinary and professional development of these writer-teachers. Through case studies of graduate students, contingent faculty, lecturers, and …

Effect Of Supplemental Prebiotics, Probiotics And Bioactive Proteins On The Microbiome Composition And Gut Physiology In C57bl6/J Mice, Ye Li

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The composition and metabolic activity of the microbiome affect many aspects of health, and there is current interest in dietary constituents that may affect this system. The purpose of this study was to evaluate the effects of a mix of probiotics, a mix of prebiotics and a bioactive protein fraction on the microbiome, when fed to mice individually and in combination. Mice were fed the total western diet (TWD) supplemented with prebiotics, probiotics, and Tri-Factor (bioactive proteins) individually and in combination for four weeks. Subsequently, effects on the composition of gut microbiome, gut short chain fatty acids (SCFAs) concentration, gut …

Resurgence Of Cocaine-Seeking In Rats Following Long Access And Punishment, Rusty W. Nall

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Strategies that provide access to alternative non-drug rewards are among the most effective at reducing substance use in individuals with substance use disorders, but relapse often occurs when alternative rewards are removed. Relapse induced by the loss of alternative rewards is called resurgence, and represents a challenge to otherwise effective strategies for reducing drug use. An animal model has been useful for studying resurgence, but the extant model has two limitations. First, humans usually refer to the negative consequences of drug use as the reason they stop taking drugs, but the extant model uses drug unavailability to reduce drug seeking. …

Nest-Site Selection Of Golden Eagles And Ferruginous Hawks And Diet Composition Of Sensitive Raptor Species Using Metabarcoding Analysis In The Uinta Basin And Ashley National Forest, Ut, Usa, Dylan J. Hopkins

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Development and climate change in the sagebrush habitats are causing population declines of North American hawks and eagles. For these species, understanding the landscape features that are preferred for nesting and the prey they consume in sagebrush habitats are important in developing conservation plans. Specifically, we know little of the preferred nest-sites and diet of Ferruginous Hawks (Buteo regalis) and Golden Eagles (Aquila chrysaetos) many locales. In our study, we determined the landscape characteristics associated with nest sites for these two raptor species in the Uintah Basin, UT to predict where nests may occur in our …

Racial Conflict In Early Utah: Mormon, Native American And Federal Relations, Raelyn M. Embleton

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

This website is for teachers to gain information and sources about Utah history during the early territorial period, specifically relating to conflicts between Mormon settlers, Native Americans, and federal officials. The content and site were designed with the C3 curriculum in mind, as such, at the bottom of this page you can find a downloadable Inquiry Design Model Blueprint. As you teach students this information, the compelling question to have students focus on is: “Does culture and the interaction of cultures shape the development of place?” Each event highlighted on this website is related to the other and demonstrates how …

The Value Of Inspection Stations For Detecting Nonindigenous Species Lacking Agricultural Significance: The Mexican Treefrog, Smilisca Baudinii Complex (Duméril And Bibron 1841) (Hylidae), Interdicted In Florida, Usa, From A Shipment Of Peppers, Louis A. Somma

Papers in Herpetology

A Mexican Treefrog, Smilisca baudinii, a nonindigenous species, was interdicted for the first time from an imported shipment of peppers. The value of agriculture inspection stations used to make these interdictions is discussed. This is a single cargo interception (Stage 1: Colautti and MacIsaac 2004) and the first record for S. baudinii intercepted in Florida. Currently no evidence suggests that S. baudinii has been successfully introduced into and established in Florida, although this species could survive climatic conditions in the southern part of the state and at the scheduled destination of this shipment.

Cargo transport of alien species is a …

Design Your Career - Design Your Life, Joshua R. Beal

Masters Theses

This research investigates the current plague of unemployment and underemployment that nearly half of qualified individuals in the field of Visual Communications are met with after graduation. Students who major in this field dedicate a tremendous amount of time, money, and energy toward developing a broad skillset that resolves critical matters of communication through visual solutions. Research has demonstrated that despite conditions that are subject to ongoing change of economy, industry, and marketplace there are contributing factors that must be addressed to overcome un/underemployment regardless of circumstances. These include an underdeveloped network of professional contacts, deficiency in recognizing or responding …

Forage News [2019-08], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Reclaiming Rundown Farms - Western KY Summer Forage Tour
• Oats for Fall Pasture or Hay
• KFGC Central KY Field Day
• The Birth of a Rotational Grazing System
• Caldwell County Horse Farm to Host Field Day

Accommodating Capital And Policing Labor: Antitrust In The Two Gilded Ages, Sandeep Vaheesan

Maryland Law Review

In enacting the antitrust laws, Congress sought to prevent big businesses from maintaining and augmenting their power through collusion, mergers, and exclusionary and predatory practices and also aimed to preserve the ability of workers to act in concert. At times, the antitrust laws have benefited ordinary Americans. Antitrust achievements include the restructuring of the oil industry in 1911, the creation of competitive market structures in the mid-twentieth century, and the termination of AT&T’s telecommunications monopoly in 1984.

Yet, the history of antitrust in the United States is not one of uninterrupted successes. Over two forty-year periods, the executive branch and …

Faculty Handbook, 2019-2020, University Of Arkansas, Fayetteville

Faculty Handbook

No abstract provided.

Innovative Empires, Marisa C. Cavin

Understanding by Design: Complete Collection

In this unit students will investigate how empires rose in certain places where plenty of resources supported innovation. It focuses on the study of four empires throughout time and space: Persian, Han Chinese, Roman, and Incan. Students will answer the questions: “How can location and time period lead to innovation?”, “How are people shaped by, and how do they shape their environments?”, and “Which innovation had the most impact?”. By critically analyzing these empires, developing research journals, and constructing arguments and evaluation of the significance of resources and innovations on these societies, students will be more prepared to understand the …

Polarization-Resolved Second Harmonic Generation Microscopy Study Of Cardiac Hypertrophy, Cai Yuan

All Dissertations

As the most important structural and functional protein of cardiomyocyte, myosin is sensitive to mechanical and hormonal stimulus during cardiac hypertrophy. Accumulating evidence suggests that the changes in myosin during cardiac hypertrophy can eventually lead to heart failure. Therefore, the effective detection of the structural changes in myosin is critical to understanding the underlying mechanisms of cardiac hypertrophy and contributes to the early diagnose and treatment of cardiac hypertrophy.

Changes in myosin during the development of cardiac hypertrophy are not limited to tissue, cellular or sub-cellular levels such as series and parallel addition of sarcomere. Before cardiac hypertrophy develops obvious …

Bayesian Spatio-Temporal Modeling For Forecasting, Trend Assessment And Spatial Trend Filtering, Stella Coker Watson Self

All Dissertations

This work develops Bayesian spatio-temporal modeling techniques specifically aimed at studying several aspects of our motivating applications, to include vector-borne disease incidence and air pollution levels. A key attribute of the proposed techniques are that they are scalable to extremely large data sets which consist of spatio-temporally oriented observations. The scalability of our modeling strategies is accomplished in two primary ways. First, through the introduction of carefully constructed latent random variables we are able to develop Markov chain Monte Carlo (MCMC) sampling algorithms that consist primarily of Gibbs steps. This leads to the fast and easy updating of the model …

2018 (30th) Report Of The Nou Records Committee, Mark A. Brogie

Nebraska Bird Review

2018 Additions/Deletions to the "Official List of the Birds of Nebraska”: There was one new species added in 2018. Fulvous Whistling-Duck (Dendrocygna bicolor) Accidental - Class 1-P. With this addition, the “Official List of the Birds of Nebraska” stands at 463 species.

2018 Changes in Frequency of Occurrence

Changes Involving Nebraska Species Due to Taxonomic Revisions

NOURC Accepted Records (Received in 2018)

NOURC Unaccepted Records (Received in 2018)

Salem Belles, Succubi, And The Scarlet Letter: Transatlantic Witchcraft And Gothic Erotic Affect, Sylvia Cutler

Theses and Dissertations

In order to reconcile the absence of sexually deviant witch figures (succubae, demonic women, etc.) within the formation of American national literature in the nineteenth century with the fantastic elements found in European variations on the gothic, my thesis aims to demonstrate transatlantic variants of erotic signifiers attached to witch figures in nineteenth-century gothic fiction and mediums across national traditions. I will begin by tracing the transatlantic and historical impact of Heinrich Kramer and Jacob Sprenger’s Malleus Maleficarum—an early modern handbook of sorts used widely in witchcraft inquisitions—on Early American witch trials, specifically where its influence deviates from a sexualized …

Understanding The Psychosocial And Physical Health Impacts Of Colorism: Discrimination Of African Americans Based On Skin Color, Latocia Keyes

Social Work Dissertations - Archive

Colorism is a complex phenomenon which was birthed by racism and uses the observable human characteristic of skin color as a metric for worth in society. Colorism as practiced since its inception demonstrates intolerance for African features and promotes acceptance based on the approximate physiological similarity to a European standard. This social construct has served as a divisive wedge in the Black community. The issue is further complicated by the dynamics of interpersonal beliefs and group socialization in a variety of settings. Skin bleaching, tanning, and chemical hair straighteners all have the potential risk to impact physical health that causes …

The Hierarchical Aversiveness Of Two Simultaneous Pains Within An Operant Approach Avoidance Paradigm, Celina Antionette Salcido

Psychology Dissertations - Archive

Pain is a subjective, private, yet universal phenomenon that depends on a unique combination of sensory, affective, and evaluative characteristics. Although preclinical models have been used to understand much of pain physiology, the inability to communicate with animals limits affective and evaluative feedback, failing to adequately represent the entire pain experience. Therefore, this study sought to characterize the affective component of pain within an operant approach-avoidance paradigm (AAP) to determine which type of pain (inflammatory or neuropathic) may be more aversive. To reveal possible differences in pain aversiveness, animals received bilateral inflammatory and neuropathic pain conditions and were be given …

Whole Body Vibration As An Innovative Intervention To Improve Physical Function And Vascular Health Within A Lifespan, Stephen Leroy Newhart Jr.

Kinesiology Dissertations - Archive

Over the past several decades, technological advances in computers, transportation devices, and other automated devices have decreased the need for human locomotion and physical activity in the workplace and at home. The need to be physically active in order to sustain and prosper in life has been almost fully eliminated by these technological advances. As a result, sedentary patterns of living have become more prevalent throughout all socioeconomic levels. Age related injuries and conditions including falls and osteoporosis can be debilitating or life ending and have been associated with sedentary behaviors as these can lead to decreased range of motion, …

Understanding The Axonal Response To Injury By In Vivo Imaging In The Mouse Spinal Cord: A Tale Of Two Branches., Binhai Zheng, Ariana O Lorenzana, Le Ma

Department of Neuroscience Faculty Papers

Understanding the basic properties of how axons respond to injury in the mammalian central nervous system (CNS) is of fundamental value for developing strategies to promote neural repair. Axons possess complex morphologies with stereotypical branching patterns. However, current knowledge of the axonal response to injury gives little consideration to axonal branches, nor do strategies to promote axon regeneration. This article reviews evidence from in vivo spinal cord imaging that axonal branches markedly impact the degenerative and regenerative responses to injury. At a major bifurcation point, depending on whether one or both axonal branches are injured, neurons may choose either a …

Longitudinal Quantification Of Adenovirus Neutralizing Responses In Zambian Mother-Infant Pairs: Impact Of Hiv-1 Infection And Its Treatment, Sara R. Privatt, Brianna L. Bullard, Eric A. Weaver, Charles Wood, John T. West

Nebraska Center for Virology: Faculty Publications

Vaccination offers the most cost-effective approach to limiting the adverse impact of infectious and neoplastic diseases that reduce the quality of life in sub-Saharan Africa (SSA). However, it is unclear what vaccine vectors would be most readily implementable in the setting and at what age they should be applied for maximal efficacy. Adenoviruses (Ad) and Ad-based vectors have been demonstrated to induce effective humoral and cellular immune responses in animal models and in humans. However, because immunity associated with Ad infection is lifelong, there exists a debate as to whether pre-existing immunity might decrease the efficacy of Ad vectored vaccines. …

An Exploration Of Attitudes Toward Dogs Among College Students In Bangalore, India, Shelly Volsche, Miriam Mohan, Peter B. Gray, Madhavi Rangaswamy

Anthropology Faculty Publications and Presentations

Conversations in the field of anthrozoology include treatment and distinction of food animals, animals as workers versus pests, and most recently, emerging pet trends including the practice of pet parenting. This paper explores attitudes toward pet dogs in the shared social space of urban India. The data include 375 pen-and-paper surveys from students at CHRIST (Deemed to be University) in Bangalore, India. Reflecting upon Serpell’s biaxial concept of dogs as a relationship of affect and utility, the paper considers the growing trend of pet dog keeping in urban spaces and the increased use of affiliative words to describe these …