Digital Commons Network^™

Rhodococcus Opacus Pd630 Genetic Tool Development To Enable The Conversion Of Biomass, Drew Michael Delorenzo

McKelvey School of Engineering Graduate Student Theses & Dissertations

The discovery of fossil fuels facilitated a new era in human history and allowed many firsts, such as the mass production of goods, the ability to travel and communicate long distances, the formation of population dense cities, and unprecedented improvements in quality of life. Alternative sources of energy and chemicals are needed, however, as hydrocarbon reserves continue to deplete and the effects of burning fossils on the planet become better understood. Lignocellulosic biomass is the most abundant raw material in the world and a viable alternative to petroleum-derived products. The pre-treatment of lignocellulose (e.g., thermocatalytic depolymerization, enzymatic hydrolysis, pyrolysis, etc.) …

A Microfluidic Platform To Investigate The Mechanism By Which Gdnf Overexpression In Schwann Cells Causes Neuronal Axon Entrapment, Ze Zhong Wang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Twenty million Americans suffer from peripheral nerve injury (PNI) caused by trauma and medical disorders, with approximately $150 billion spent in annual health-care dollars in the United States. Even with proper surgical reconstruction, less than 50% of the patients achieve satisfactory functional recovery. The gold standard surgical repair for long gaps (>3cm) is the autologous nerve graft, despite its disadvantages such as donor site morbidity, risk of infection, and increased cost. Alternative methods, such as acellular nerve grafts (ANA), are ineffective for large lesion gaps because of the lack of cells and regeneration factors. Recent efforts have been focused …

Three-Dimensional Image Reconstruction In Transcranial Photoacoustic Computed Tomography, Joemini Poudel

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic computed tomography (PACT) is an emerging imaging modality that exploitsoptical contrast and ultrasonic detection principles to form images of the photoacousticallyinduced initial pressure distribution within tissue. The PACT reconstruction problemcorresponds to an inverse source problem in which the initial pressure distribution is recoveredfrom measurements of the radiated pressure wavefield. A major challenge in transcranialPACT brain imaging is compensation for aberrations in the measured data due to the presenceof the skull. Ultrasonic waves undergo absorption, scattering and longitudinal-to-shear wavemode conversion as they propagate through the skull. To properly account for these effects, awave-equation-based inversion method should be employed that can …

Transcriptional Regulation Of Adipose Tissue Development By Pexrap And Med19, John Dean

Arts & Sciences Graduate Student Theses and Dissertations

Targeting adipose tissue function to decrease adiposity and improve insulin sensitivity could treat obesity and diabetes. How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat (BAT and WAT), as well as the browning of white fat, remains unclear. Our previous studies suggest that PexRAP, a peroxisomal lipid synthetic enzyme, regulates PPARγ signaling and white adipogenesis.Here, we show that PexRAP is an inhibitor of brown adipocyte gene expression. PexRAP inactivation promoted adipocyte browning, increased energy expenditure, and decreased adiposity. Identification of PexRAP-interacting proteins suggests that PexRAP function extends beyond its …

Young Children’S Knowledge About The Role Of Print In Reading, Molly Farry-Thorn

Arts & Sciences Graduate Student Theses and Dissertations

Children begin to learn about the print in books and the role it plays in reading well before the onset of formal literacy instruction. Young children’s knowledge about precisely what readers are reading when they read books and who is able to read books has been studied primarily through interviews, but conclusions from this research are limited by methodological concerns. Three experiments examined whether pre-readers understand what part of a book is read and whether they distinguish between the skill of reading and the activity of reading. Although pre-readers were typically able to locate the print in a book, they …

T Cell Immunity In Pancreatic Cancer Is Undermined By Dendritic Cell Dysfunction, Samarth Hegde

Arts & Sciences Graduate Student Theses and Dissertations

Pancreatic cancer carries a dismal prognosis, and desperately needs viable therapeutic interventions beyond chemo-radiation. T cell-dependent immunotherapies have shown great promise in several tumor types, but have not been effective for the vast majority of pancreatic cancer patients. This is, in part, due to our limited understanding of how antigenicity of pancreatic lesions is recognized, and how adaptive immunity is overcome in this disease. We sought to study tumor-immune interactions and identify mechanisms for this immune-failure using several spontaneous and unperturbed mouse models of pancreatic adenocarcinoma. We found that early pancreatic lesions fail to elicit tumor-limiting CD4+ TH1 and CD8+ …

Crip Time In Fin-De-Siècle Spain: Disability, Degeneration, And Eugenics, Erika Rodriguez

Arts & Sciences Graduate Student Theses and Dissertations

A period of intense nation-building, the late nineteenth century was marked by the search for medical and legal solutions to the increasing number of bodies that did not align with culturally constructed expectations of productivity and reproduction in Spanish modernity. Authors of this time used representations of disability to engage in urgent political questions about population control and the rights of individuals in the face of increasing medical intervention. In carrying out this analysis, I raise the question of how representations of disability created a space to reconfigure the social values that determined what lives matter. Focusing on canonical realist …

Generation And Utilization Of Diverse Memory B Cells After Flavivirus Challenges, Rachel Wong

Arts & Sciences Graduate Student Theses and Dissertations

Over the course of an effective immune response to an infection, two distinct B cell populations are generated to provide protection against reinfection, long-lived plasma cells (LLPCs) and memory B cells (MBCs). LLPCs and MBCs originate from germinal center (GC) B cells that have undergone B cell receptor (BCR) affinity maturation through iterative rounds of somatic hypermutation, proliferation, and selection. Thus, LLPCs and MBCs can bind to their antigen with higher affinity than their naïve B cell precursors. LLPCs constitutively secrete antibodies and can provide sterilizing immunity that pre-exists subsequent infections. MBCs, on the other hand, are quiescent and provide …

Consequences Of Math Anxiety And Stereotype Threat: An Intersectional Perspective, Jennifer E. John Buck

UNLV Theses, Dissertations, Professional Papers, and Capstones

Individuals with science, technology, engineering, and math (STEM) skills are highly valued for their contribution to the U.S. workforce and society. However, women and some people of color enter STEM fields at lesser rates than do White men. Math anxiety and stereotype threat have been found to cause math performance decrements for women and some people of color. Presently, it is not clear how math anxiety and stereotype threat might work together to dually influence math performance and subsequent STEM participation. The current study focuses on a diverse sample of 295 undergraduate students who were randomly assigned to one of …

Urinary Excretion Of Mimosine Derivatives By Cows With And Without Experience In Consumption Of Leucaena Leucocephala, N. E. Ruz-Ruiz, Eduardo G. Briceño-Poot, A. J. Ayala-Burgos, C. F. Aguilar-Pérez, Francisco J. Solorio-Sánchez, Luis Ramírez-Avilés, Juan C. Ku-Vera

IGC Proceedings (1977-2023)

Leucaena leucocephala is a leguminous tree widely distributed in the tropical regions of the world. In Mexico, it has been incorporated into silvopastoral systems and is highly regarded, owing to its high content of crude protein. Nonetheless, L. leucocephala contains secondary metab-olites, such as mimosine, a non-protein free amino acid, which may induce toxic effects in unadapted ruminants that consume the forage (Hammond 1995). Although Synergistes jonesii, an anaerobic bacterium, has the ability to degrade 3,4-DHP and 2,3-DHP to non-toxic compounds (Allison et al. 1992), in Mexico its presence has not yet been confirmed. Recent work has suggested …

Urinary Excretion Of Mimosine Metabolites By Hair Sheep Fed Foliage Of Leucaena Leucocephala, L. M. Contreras-Hernández, N. E. Ruz-Ruiz, Eduardo G. Briceño-Poot, Luis Ramírez-Avilés, A. J. Ayala-Burgos, C. F. Pérez-Aguilar, Francisco J. Solorio-Sánchez, Juan C. Ku-Vera

IGC Proceedings (1977-2023)

Leucaena leucocephala is an adapted legume widely distributed in the tropical regions of Mexico. The high crude protein content of leucaena leaves renders it appropriate for ruminant feeding under commercial conditions. However, the foliage contains the non-protein amino acid mimosine, which, if consumed in high amounts, may induce toxicity in animals which have not previously consumed the legume or without microorganisms capable of degrading mimosine and its derivatives 2,3-DHP (dihydroxypyridine) and 3,4-DHP (Hammond 1995, Palmer et al. 2010, Dalzell et al. 2012). Barros-Rodríguez et al. (2012) found that dry matter intake and weight gain were reduced when …

Animal Production From New Panicum Maximum Genotypes In The Amazon Biome, Brazil, Carlos M. S. De Andrade, Luis H. E. Farinatti, Hemython L. B. Do Nascimento, Andressa De Q. Abreu, Liana Jank, Giselle M. L. De Assis

IGC Proceedings (1977-2023)

The Panicum maximum breeding program coordinated by the Brazilian Agricultural Research Corporation - Embrapa has been evaluating and selecting genotypes under different soil and climatic conditions, with the objective to release new cultivars adapted to the diverse regions of Brazil. For the Amazon biome, small-plot experiments carried out in Acre between 2003 and 2005 allowed the selection of some promising genotypes (Valentim and Andrade 2005; Valentim et al. 2006; Andrade and Valentim 2009), with higher potential for forage growth than cultivars on the market. The objective of this work was to compare 2 new P. maximum genotypes with cv. …

ProgardesTm: A Legume For Tropical/Subtropical Semi-Arid Clay Soils, Christopher Gardiner, Nick Kempe, Iain Hannah, Jim Mcdonald

IGC Proceedings (1977-2023)

The range of available sown pasture legumes for the vast heavy clay soil regions of northern Australia has long been regarded as being deficient (Burt 1993; Jones and Clem 1997; Pengelly and Conway 2000). Indeed immense areas of northern Australia’s semi-arid clay soil regions have no sown pasture legume with proven adaptation and persistence through the long annual dry seasons (Gardiner and Swan 2008). The genus Desmanthus is a Mimosaceae legume containing some 24 species which are native to the Americas and range from being herbaceous to suffruticose in habit (Luckow 1993). Desmanthus is one of the very few legumes …

Status Of Animal Feed Resources In Rwanda, M. Mutimura, A. B. Lussa, J. Mutabazi, C. B. Myambi, R. A. Cyamweshi, C. Ebong

IGC Proceedings (1977-2023)

Animal feed resources remain a major constraint for livestock development in tropical Africa. In Rwanda, grazing lands are shrinking sharply because crop cultivation is progressively encroaching on grazing areas with increasing human pressure (Mutimura and Everson 2011). Therefore, over 60% of households cultivating less than 0.7 ha, and owning livestock, practise zero-grazing, where farmers cut-and-carry forage and crop residues to feed animals that are kept exclusively under sheds (MINAGRI 2009). In general, the main feed for dairy cattle under a zero-grazing system is Napier grass (Pennisetum purpureum). For more than a decade, efforts to improve the feed resource …

Effect Of Cutting Interval On Yield And Quality Of Three Brachiaria Hybrids In Thailand, Michael D. Hare, Supaphan Phengphet, Theerachai Songsiri, Naddakorn Sutin, Eduardo Stern

IGC Proceedings (1977-2023)

In field trials in Thailand, Brachiaria hybrid cv. Mulato II produced significantly more green leaf, particularly during the dry season, than other brachiaria grasses (Hare et al. 2009). Cultivar Cayman produced more dry matter (DM) than Mulato II in one out of 3 wet seasons, and line BRO2/1794 produced similar DM yields to Mulato II (Pi-zarro et al. 2013).

The objective of this field study was to determine the effects of varying cutting intervals on growth and forage quality of hybrid brachiaria grasses in Thailand on infertile soils.

Leucaena Toxicity: A New Perspective On The Most Widely Used Forage Tree Legume, Michael J. Halliday, Jagadish Padmanabha, Chris S. Mcsweeney, Graham L. Kerven, H. Max Shelton

IGC Proceedings (1977-2023)

The tree legume Leucaena leucocephala (leucaena) is a high quality ruminant feed, vitally important for livestock production in the tropics despite the presence of mimosine in the leaves. This toxic non-protein amino acid has the potential to limit productivity and adversely affect the health of animals. The discovery and subsequent distribution in Australia of the ruminal bacterium Synergistes jonesii as an oral inoculum was shown in the 1980s to overcome these toxic effects. However, recent surveys of the status of toxicity worldwide; improved understanding of the chemistry and mode of action of the toxins; new techniques for molecular sequencing; and …

Review: Sustaining The Commons (Arizona State University), Chelsie Romulo

Open Textbooks & Reviews

Review of the textbook Sustaining the Commons originally published on Open Textbook Library (https://open.umn.edu/opentextbooks/textbooks/sustaining-the-commons).

Georgic Rhetoric, Virtue And The Commercialization Of Agriculture In Pennsylvania From 1785 To 1870, Naomi Ulmer

Masters Theses, 2010-2019

This research examines how farmers in Pennsylvania between 1785 and 1870 were persuaded by georgic agrarianism to take social, economic and even moral risks to abandon a semi-subsistence mode of production in favor of commercial production. The georgic rhetoric is derived from Virgil’s poem “The Georgics.” It discusses agriculture and man’s labor in nature. Virgil discusses the relationship between man, nature and his ability, or inability, to control nature to ensure his own survival. Beginning in the late 18^th century, supporters of improved agriculture, mostly wealthy and upper-class gentlemen, tried to persuade common yeomen farmers to produce for the …

Long-Term Study Of Prescribed Fire Effects On Stand Dynamics And Oak Regeneration Potentials In Degraded Upland Oak-Hickory Stands In Northwestern Arkansas, Mason C. Danheim, Kathryn R. Kidd Dr, Hal O. Liechty Dr, Brian P. Oswald Dr

Electronic Theses and Dissertations

Upland oak-hickory forests in the Ozark Mountains of northwestern Arkansas and south central Missouri were impacted by oak decline during the early 2000s. This decline event was caused by predisposing (e.g., mature, dense stand conditions), inciting (i.e., drought), and contributing (e.g., red oak borer, E. rufulus H., outbreak) factors. Immediately following onset of the decline, substantial crown dieback and tree mortality, particularly for two red oak species (northern red oak, Quercus rubra Michx. and black oak, Q. velutina Lam.), were observed. In addition, densities of advanced oak regeneration were inadequate at this time, resulting in poor regeneration potentials for …

Influence Of Biosolids Upon The Uptake Of Mn And Cd By Radish (Raphanus Sativus L.), Oluwadamilola O. Fateru

Electronic Theses and Dissertations

The influence of biosolids upon the uptake of Mn and Cd by radish (Raphanus sativus L.) was investigated through the characterization of biosolids, sequential extraction of the biosolids, and the determination of the metal content in the root, shoot and leaves of radish (Raphanus sativus L.).The biosolid samples from Nacogdoches Wastewater Sludge (NWWS), Lufkin Wastewater Sludge (LWWS), Soil Therapy Compost (STC) had pHs between 5.33 – 6.74. The elemental compositions of the biosolid samples were determined using inductively coupled plasma optical emission spectroscopy (ICP-OES) and SEM/EDX. Major elements (K, Mg, Mn, P) needed for plant growth …

Authors Of Independence: Comparing Thomas Paine And Camilo Henríquez As Revolutionary Writers, Sean Gray

History & Classics Student Scholarship

An nineteenth-century Chilean writer, Fr. Camilo Henriquez was a fascinating figure—a Catholic priest whose religious beliefs more closely aligned with Deism, a prolific proponent of Chilean independence, and, for a short while, the president of the Chilean Senate. Because of his role in creating La Aurora, the first Chilean newspaper, Henríquez is often considered the “father of Chilean journalism” and the “mentor of the revolution." But to understand his role in the Chilean independence movement, we must juxtapose him with Thomas Paine, the pamphleteer extraordinaire of the American Revolution. The Enlightenment’s ideals of liberty and equality influenced both men, and, …

My Experience Manifesto, Xuechun Wu

Theses

In contemporary society, people tend to judge and evaluate the growth and development status of others to different degrees. Also, people are easily persuaded by others' judgments, gossip, and appraisement. However, people ignore the importance of both their backstories and those of others; thus, a person may make subjective and incomplete value judgments.

The first approach of my project included an illustration of a typical story of a Chinese woman at turning points of her life: childhood, puberty, teenage rebellion, marriage, and menopause. The purpose of this illustration is to make the audience imagine and resonate with the different turning …

Comparison Of Feeding Diets Diluted With Sorghum-Sudangrass Silage Or Low-Quality Grass On Nutrient Intake And Digestibility And Growth Performance Of Holstein Dairy Heifers, Lingyan Li, Nancy M. Esser, Robin K. Ogden, Wayne K. Coblentz, Matthew S. Akins

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

This study was carried out to evaluate the nutrient intakes and growth of dairy heifers offered an alfalfa silage– corn silage diet (CON; 14.3% crude protein, 61.1% total digestible nutrients, 47.9% neutral detergent fiber) compared with diets containing 1 of 2 types of sorghumsudangrass (SS) silages: conventional or photoperiod sensitive. The objective of the study was to determine the potential to use SS to control dry matter (DM) and nutrient intakes and weight gain. Both diets were similar in nutrient composition, with approximately 13% crude protein, 60 to 61% total digestible nutrients, and 55% neutral detergent fiber. Seventy-two Holstein heifers …

Metaphors We Think By, Aldis H. Petriceks

Journal of Wellness

N/A

Development Of A Porcine Model Of Severe Noncompressible Truncal Hemorrhage, Ujwal R. Yanala, Jason Johanning, Iraklis Pipinos, William Velander, Mark Carlson

Graduate Medical Education Research Journal

No abstract provided.

Outcomes Of Intragastric Balloon Placements: An Analysis Of The 2016 Mbsaqip Database, Bhavani Pokala, Priscila Armijo, Dmitry Oleynikov

Graduate Medical Education Research Journal

No abstract provided.

Global Trends In Esophageal Cancer, Gautam K. Malhotra, Ujwal Yanal, Advaitaa Ravipati, Matthew Follet, M. Vijayakumar, Chandrakanth Are

Graduate Medical Education Research Journal

No abstract provided.

National Trends In Survival For Pancreatic Adenocarcinoma Based On Location Of The Primary Lesion, Gautam K. Malhotra, Lynette M. Smith, Quan P. Ly, Aaron R. Sasson, Chandrakanth Are

Graduate Medical Education Research Journal

No abstract provided.

Renal Sympathetic Vasomotion Monitoring As A Novel Method For Intraprocedural Feedback For Renal Denervation, Peter Ricci Pellegrino Et Al, Alicia M. Schiller, Han-Jun Wang, Yiannis S. Chatzizisis, Irving H. Zucker

Graduate Medical Education Research Journal

No abstract provided.

Synthetic Resorbable Vs. Cellulose Bandage For Minor Hemorrhage In A Porcine Model, Ujwal R. Yanala, Sandra Noriega, Ruben Spretz, Jorge Ragusa, Luis Nunez, Gustavo Larsen, Mark Carlson

Graduate Medical Education Research Journal

No abstract provided.