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2019

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Laboratory Animal Welfare And Human Attitudes: A Cross-Sectional Survey On Heterospecific Play Or “Rat Tickling”, Megan R. Lafollette, Sylvie Cloutier, Colleen Brady, Brianna N. Gaskill, Marguerite E. O'Haire Aug 2019

Laboratory Animal Welfare And Human Attitudes: A Cross-Sectional Survey On Heterospecific Play Or “Rat Tickling”, Megan R. Lafollette, Sylvie Cloutier, Colleen Brady, Brianna N. Gaskill, Marguerite E. O'Haire

Purdue University Libraries Open Access Publishing Fund

Introduction

Laboratory rat welfare is critically influenced by laboratory animal personnel through their implementation, or lack of implementation, of various enrichment techniques. One such promising technique is heterospecific play, or “rat tickling”, which mimics aspects of rat rough-and-tumble play and can contribute to improving welfare, but may be infrequently implemented. The theory of planned behavior can be used to study implementation by measuring intentions and beliefs about rat tickling, including behavioral attitudes (whether it is good or bad), subjective norms (whether there is social/professional pressure to provide it), and control beliefs (whether they feel in control of providing it). Therefore, …


Loss Of Developmental Diapause As Prerequisite For Social Evolution In Bees, Priscila Karla Ferreira Santos, Maria Cristina Arias, Karen M. Kapheim Aug 2019

Loss Of Developmental Diapause As Prerequisite For Social Evolution In Bees, Priscila Karla Ferreira Santos, Maria Cristina Arias, Karen M. Kapheim

Biology Faculty Publications

Diapause is a physiological arrest of development ahead of adverse environmental conditions and is a critical phase of the life cycle of many insects. In bees, diapause has been reported in species from all seven taxonomic families. However, they exhibit a variety of diapause strategies. These different strategies are of particular interest since shifts in the phase of the insect life cycle in which diapause occurs have been hypothesized to promote the evolution of sociality. Here we provide a comprehensive evaluation of this hypothesis with phylogenetic analysis and ancestral state reconstruction (ASR) of the ecological and evolutionary factors associated with …


Community Attitudes Toward Complementary, Alternative And Integrative Medicine In North Hartford, Connecticut, Andria Matthews Aug 2019

Community Attitudes Toward Complementary, Alternative And Integrative Medicine In North Hartford, Connecticut, Andria Matthews

Master's Theses

Background: This study explores the attitudes of residents of North Hartford, CT toward Complementary, Alternative and Integrative Medicine. Methods: Twenty-five semi-structured, 10-15 minute in-person interviews were conducted at five sites over a two-week period in March 2019. Results: Few respondents were familiar with the term “Integrative Medicine.” Familiarity with modalities such as massage was higher (92%). Massage therapy was most often tried in the past (56%). Meditation and relaxation and yoga were the most frequently requested offerings. Cost, transportation, time of day and day of week, all emerged as potential barriers to participation. Pain-related complaints were prevalent amongst respondents. Conclusions: …


Aventurescence, Gracia E. Nash Aug 2019

Aventurescence, Gracia E. Nash

Theses

Aventurescence explores ideas of comfort and identity through glass and the body. I am interested in the material qualities and limitations of glass, including luminosity, flexibility, and fragility; and the ways in which these can be expressed and communicated through the body. To expand the material’s flexibility I used a combination of multiple glass bodies and silicones to create glass textiles and objects with flexible surfaces. I also used traditional fusing methods and alternative glasses (reflective glass beads) to create sheets and screens. These objects and textiles parallel skin, and communicate with the body through object, performance, and the consequent …


Play Behaviors Of Young Children With And Without Expressive Language Delay: An Exploratory Study, Brianna Hendrickson, Shari L. Deveney, Lisa Kelly-Vance Aug 2019

Play Behaviors Of Young Children With And Without Expressive Language Delay: An Exploratory Study, Brianna Hendrickson, Shari L. Deveney, Lisa Kelly-Vance

Journal of Curriculum, Teaching, Learning and Leadership in Education

The association between language and play development during the early years of children’s lives is important as tremendous growth in development occurs in both at this time. Literature has suggested that if children have less developed language abilities, they may also have less developed play skills. The aim of the current exploratory study was to observe and categorize children’s play behavior using a comprehensive play assessment tool. This tool, the Play in Early Childhood Evaluation System (PIECES) coding scheme developed by Kelly-Vance and Ryalls (2005, 2014), provides information on differences in percentage of time in exploratory, simple pretend, and complex …


To Equip Tomorrow's Cybersecurity Experts, We'll Need An Open Approach, Brandon Dixon, Randall Joyce Aug 2019

To Equip Tomorrow's Cybersecurity Experts, We'll Need An Open Approach, Brandon Dixon, Randall Joyce

Faculty & Staff Research and Creative Activity

An open approach to training the next generation of cybersecurity experts can fully equip them to combat a constantly shifting threat landscape.


Selective Alteration Of The Root Morphology Of Arabidopsis Thaliana By Synthetic Anion Transporters (Sats), Mohit Patel, Evan Garrad, Steven Korb, Saeedeh Negin, Michael Gokel, Sergey Sedinkin, Shanheng Yin, George Gokel Aug 2019

Selective Alteration Of The Root Morphology Of Arabidopsis Thaliana By Synthetic Anion Transporters (Sats), Mohit Patel, Evan Garrad, Steven Korb, Saeedeh Negin, Michael Gokel, Sergey Sedinkin, Shanheng Yin, George Gokel

Chemistry & Biochemistry Faculty Works

No abstract provided.


Temperature Triggers A Non-Linear Response In Resource–Consumer Interaction Strength, Gustavo S. Betini, Tal Avgar, Kevin S. Mccann, John M. Fryxell Aug 2019

Temperature Triggers A Non-Linear Response In Resource–Consumer Interaction Strength, Gustavo S. Betini, Tal Avgar, Kevin S. Mccann, John M. Fryxell

Wildland Resources Faculty Publications

Although temperature is recognized as a major determinant of many ecological processes, it is still not clear whether temperature increase caused by climate change will strengthen or weaken species interactions. One hypothesis is that interactions will respond non‐monotonically to temperature because thermal performance curves, which determine the strength of these interactions, are also non‐monotonic. To evaluate this hypothesis, we developed a temperature‐dependent consumer–resource model and tested predictions from this model in large freshwater mesocosms populated with green algae (Chlorella vulgaris) and herbivorous zooplankton (Daphnia magna). We found both in the model simulations and empirical investigations that …


Stigall Quoted About Discovery Of Spaceship-Shaped Cambrian Arthropod, Ohio University College Of Arts & Sciences Aug 2019

Stigall Quoted About Discovery Of Spaceship-Shaped Cambrian Arthropod, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Imaging Of Glucose Metabolism By 13c-Mri Distinguishes Pancreatic Cancer Subtypes In Mice, Shun Kishimoto, Jeffrey R. Brender, Daniel R. Crooks, Shingo Matsumoto, Tomohiro Seki, Nobu Oshima, Hellmut Merkle, Penghui Lin, Galen Reed, Albert P. Chen, Jan Henrik Ardenkjaer-Larsen, Jeeva Munasinghe, Keita Saito, Kazutoshi Yamamoto, Peter L. Choyke, James Mitchell, Andrew N. Lane, Teresa W. M. Fan, W. Marston Linehan, Murali C. Krishna Aug 2019

Imaging Of Glucose Metabolism By 13c-Mri Distinguishes Pancreatic Cancer Subtypes In Mice, Shun Kishimoto, Jeffrey R. Brender, Daniel R. Crooks, Shingo Matsumoto, Tomohiro Seki, Nobu Oshima, Hellmut Merkle, Penghui Lin, Galen Reed, Albert P. Chen, Jan Henrik Ardenkjaer-Larsen, Jeeva Munasinghe, Keita Saito, Kazutoshi Yamamoto, Peter L. Choyke, James Mitchell, Andrew N. Lane, Teresa W. M. Fan, W. Marston Linehan, Murali C. Krishna

Center for Environmental and Systems Biochemistry Faculty Publications

Metabolic differences among and within tumors can be an important determinant in cancer treatment outcome. However, methods for determining these differences non-invasively in vivo is lacking. Using pancreatic ductal adenocarcinoma as a model, we demonstrate that tumor xenografts with a similar genetic background can be distinguished by their differing rates of the metabolism of 13C labeled glucose tracers, which can be imaged without hyperpolarization by using newly developed techniques for noise suppression. Using this method, cancer subtypes that appeared to have similar metabolic profiles based on steady state metabolic measurement can be distinguished from each other. The metabolic maps from …


Rna-Based Compositions And Adjuvants For Prophylactic And Therapeutic Treatment, Peixuan Guo, Hui Li, Emil F. Khisamutdinov, Daniel L. Jasinski Aug 2019

Rna-Based Compositions And Adjuvants For Prophylactic And Therapeutic Treatment, Peixuan Guo, Hui Li, Emil F. Khisamutdinov, Daniel L. Jasinski

Pharmaceutical Sciences Faculty Patents

The present invention is directed towards an artificial RNA nano structure comprising multiple external strands of RNA, each external strand comprising about 40-50 nucleotides; one internal strand of RNA comprising more than about 50 nucleotides; the internal strands and external strands assembled to form a triangle nanostructure, a square nanostructure, or a polygon nanostructure and a pRNA three-way junction (3WJ) motif at each vertex of the nanostructure. Such nanostructure can be provided in a composition together with an adjuvant for use in inducing the production of high affinity neutralizing antibodies or inhibitory antibodies, inducing the production of cytokines, inducing an …


Small Molecules That Mimic Or Antagonize Actions Of Granulocyte Colony-Stimulating-Factor (G-Csf), Juan Sanchez-Ramos, Vasyl Sava, Shijie Song, Said Sebti Aug 2019

Small Molecules That Mimic Or Antagonize Actions Of Granulocyte Colony-Stimulating-Factor (G-Csf), Juan Sanchez-Ramos, Vasyl Sava, Shijie Song, Said Sebti

USF Patents

Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial agonists/antagonists of G-CSF. Further provided herein are methods of treating a condition, including, for example, a neurodegenerative disease, by administering a compound as detailed herein.


Nutraceutical Co-Crystal Compositions, Michael John Zaworotko, Heather Clarke, Arora Kapildev, Padmini Kavuru, Roland Douglas Shytle, Twarita Pujari, Lissette Marshall, Tien Teng Ong Aug 2019

Nutraceutical Co-Crystal Compositions, Michael John Zaworotko, Heather Clarke, Arora Kapildev, Padmini Kavuru, Roland Douglas Shytle, Twarita Pujari, Lissette Marshall, Tien Teng Ong

USF Patents

Co-crystals comprising at least one nutraceutical compound and at least one co-crystal former with or without impurities. These co-crystals may be included in compositions (optionally also including other components such as pharmaceutically acceptable excipients, other nutritional supplements, etc.) having utility as pharmaceuticals, nutraceuticals, nutritional supplements, and foodstuffs.


Astragaloside Iii Enhances Anti-Tumor Response Of Nk Cells By Elevating Nkg2d And Ifn-Γ, Xingmeng Chen, Xi Chen, Junxiao Gao, Han Yang, Yue Duan, Benjamin Feng, Xin He, Xiaoqun Gong, Hanjie Wang, Xiaoli Wu, Jin Chang Aug 2019

Astragaloside Iii Enhances Anti-Tumor Response Of Nk Cells By Elevating Nkg2d And Ifn-Γ, Xingmeng Chen, Xi Chen, Junxiao Gao, Han Yang, Yue Duan, Benjamin Feng, Xin He, Xiaoqun Gong, Hanjie Wang, Xiaoli Wu, Jin Chang

Peer Reviewed Articles

Natural killer (NK) cells play an irreplaceable role in the development of colon cancer, in which antitumor function of NK cells was impaired. Astragaloside III is a natural compound from Astragalus that has been shown to have immunomodulatory effects in various systems. However, few studies have evaluated the antitumor effects of Astragaloside III through stimulating systemic immunity and regulating NK cells. In this study, flow cytometry, immunohistochemical analysis, and immunofunctional assays were performed to elucidate the functions of Astragaloside III in restoring antitumor function of NK cells. We demonstrated that Astragaloside III significantly elevated the expression of natural killer group …


The "Glue" To Watson Labs, Kelly Sennott Aug 2019

The "Glue" To Watson Labs, Kelly Sennott

UNH Today Archive

No abstract provided.


Monitoring Silane Sol-Gel Kinetics With In-Situ Optical Turbidity Scanning And Dynamic Light Scattering, Abul Bashar Mohammad Giasuddin, David W. Britt Aug 2019

Monitoring Silane Sol-Gel Kinetics With In-Situ Optical Turbidity Scanning And Dynamic Light Scattering, Abul Bashar Mohammad Giasuddin, David W. Britt

Biological Engineering Faculty Publications

Organosilanes (e.g., R’-SiOR3) provide hydrophobic functionality in thin-film coatings, porous gels, and particles. Compared with tetraalkoxysilanes (SiOR4), organosilanes exhibit distinct reaction kinetics and assembly mechanisms arising from steric and electronic properties of the R’ group on the silicon atom. Here, the hydrolysis and condensation pathways of n-propyltrimethoxy silane (nPM) and a tri-fluorinated analog of nPM, 3,3,3-trifluoropropyl trimethoxy silane (3F), were investigated under aqueous conditions at pH 1.7, 2.0, 3.0, and 4.0. Prior to hydrolysis, 3F and nPM are insoluble in water and form a lens at the bottom (3F) or top (nPM) of the solutions. This …


Tpp And Environmental Regulation, Errol E. Meidinger Aug 2019

Tpp And Environmental Regulation, Errol E. Meidinger

Contributions to Books

Published as Chapter 8 in Megaregulation Contested: Global Economic Ordering After TPP, Benedict Kingsbury, David M. Malone, Paul Mertenskötter, Richard B. Stewart, Thomas Streinz & Atsushi Sunami, eds.

This article examines the environment-related provisions of the Trans-Pacific Partnership Agreement (TPP) to assess how and how much they contribute to a larger megaregulatory program for the Asia-Pacific region. The TPP calls for ‘high levels’ of environmental protection and effective enforcement; incorporates duties from several multilateral environmental agreements; adds new provisions addressing several important environmental problems; mandates administrative best practices; promotes corporate social responsibility and the use of voluntary certification systems; and …


Comparison Of Intraoperative Outcomes Between Single-Incision Robotic Cholecystectomy And Multi-Incision Robotic Cholecystectomy., Philip Schertz, Subhasis Misra, David Livert, Joanne Mulligan, Chand Rohatgi Md Aug 2019

Comparison Of Intraoperative Outcomes Between Single-Incision Robotic Cholecystectomy And Multi-Incision Robotic Cholecystectomy., Philip Schertz, Subhasis Misra, David Livert, Joanne Mulligan, Chand Rohatgi Md

Department of Surgery

Background The aim of this study was to evaluate the differences in the key surgical factors for single-incision robotic cholecystectomy (SIRC) and multi-incision robotic cholecystectomy (MIRC). Methods A retrospective data review from August 2013 to April 2018 consisting of 104 SIRC and 105 MIRC cases was done considering factors including patient gender, age, operating time (skin incision to skin closure), robotic console time (docking to undocking), the preoperative diagnosis for surgery, any complications in surgery, length of stay (LOS), and estimated blood loss (EBL). Procedures with conversion away from original robotic cholecystectomy approach were excluded. Chi-square analysis (


Dissociable Learning Processes, Associative Theory, And Testimonial Reviews: A Comment On Smith And Church (2018, Andy J. Wills, Charlotte E.R. Edmunds, Pelley M Le, Fraser Milton, Ben R. Newell, Dominic M. Dwyer, David R. Shanks Aug 2019

Dissociable Learning Processes, Associative Theory, And Testimonial Reviews: A Comment On Smith And Church (2018, Andy J. Wills, Charlotte E.R. Edmunds, Pelley M Le, Fraser Milton, Ben R. Newell, Dominic M. Dwyer, David R. Shanks

School of Psychology

No abstract provided.


Vision In An Abundant North American Bird: The Red-Winged Blackbird, Esteban Fernández-Juricic, Patrice E. Baumhardt, Luke P. Tyrrell, Amanda Elmore, Shelagh T. Deliberto, Scott J. Werner Aug 2019

Vision In An Abundant North American Bird: The Red-Winged Blackbird, Esteban Fernández-Juricic, Patrice E. Baumhardt, Luke P. Tyrrell, Amanda Elmore, Shelagh T. Deliberto, Scott J. Werner

United States Department of Agriculture Wildlife Services: Staff Publications

Avian vision is fundamentally different from human vision; however, even within birds there are substantial between species differences in visual perception in terms of visual acuity, visual coverage, and color vision. However, there are not many species that have all these visual traits described, which can constrain our ability to study the evolution of visual systems in birds. To start addressing this gap, we characterized multiple traits of the visual system (visual coverage, visual acuity, centers of acute vision, and color vision) of the Red-winged Blackbird (Agelaius phoeniceus), one of the most abundant and studied birds in North America. We …


An Intercultural Dialogue Between Confucianism And Western Philosophies Concerning Approaches To Family: A Report From A Workshop, Muzi Marilyn Fang Aug 2019

An Intercultural Dialogue Between Confucianism And Western Philosophies Concerning Approaches To Family: A Report From A Workshop, Muzi Marilyn Fang

Comparative Philosophy

No abstract provided.


Respect, Jing, And Person, Pengbo Liu Aug 2019

Respect, Jing, And Person, Pengbo Liu

Comparative Philosophy

While respect for persons is fundamental to many moral and political theories, its nature and ground remain controversial. According to the standard model of respect, respect is primarily a response to certain inherent features of a person or an object. Importantly, it is in virtue of the value, status or authority of those features that respect is justified or owed. This model, however, faces many serious challenges. Drawing on the classical Confucian notion of jing (敬), I develop an alternative model of respect, which construes respect as an expression of agent’s sense of the self and its place in …


Yi-Jing Integral (Yi): A New Natural And Cosmic Ba-Gua, Harry Donkers Aug 2019

Yi-Jing Integral (Yi): A New Natural And Cosmic Ba-Gua, Harry Donkers

Comparative Philosophy

In this paper we elaborate on the neo-Confucian interpretation of the Yi-Jing system. Based on a further exploration of the Diagram of the Supreme Polarity of Zhou Dunyi, we develop a cosmological-anthropological model in constructive engagement with Western thoughts and views on systems and on the universe. The vital energy (qi) and the pattern (li) play central roles in this model and also in the interpretation of the images and forces of the trigrams. This leads to a comparative model, based on a quadrant system with four perspectives: naturality, rationality, humanity and morality. This model fits …


Panic Word, Tajinder Gadh, Marc Stogaitis Aug 2019

Panic Word, Tajinder Gadh, Marc Stogaitis

Defensive Publications Series

A computing device (e.g., a mobile phone, camera, tablet computer, etc.) may include an integrated display device (e.g., a presence-sensitive screen) at which a user interface is presented. Additionally, a computing device may include a microphone that generates audio data and the capability to process the audio data. For instance, the computing device may process the audio data to identify one or more commands or requests spoken by a user of the computing device, and perform various actions associated with those commands or requests. In some situations, a user may desire for the computing device to perform one or more …


The Drover Boy, Author Unknown Aug 2019

The Drover Boy, Author Unknown

Broadside Ballads: England

A man herds his animals and returns home to his wife.


A New Species Of Catalinia Soleglad Et Al., 2017 (Scorpiones: Vaejovidae) From Southern California, Usa, Rolando Teruel, Brandon Myers Aug 2019

A New Species Of Catalinia Soleglad Et Al., 2017 (Scorpiones: Vaejovidae) From Southern California, Usa, Rolando Teruel, Brandon Myers

Euscorpius

Herein we describe a new species of the vaejovid scorpion genus Catalinia Soleglad, Ayrey, Graham & Fet, 2017. It was collected in a single locality of the northwestern foothills of the Santa Ana Mountains. It is most closely related to both Catalinia andreas (Gertsch & Soleglad, 1972) and C. minima (Kraepelin, 1911), but is clearly distinguished by tegumentary sculpture, morphometric ratios and pectinal tooth counts. The new species is described and illustrated in detail, with some ecological data included; moreover, a minor correction is introduced to the diagnosis of the genus.


Approximate Free Space Construction And Maximum Clearance Path Planning For A Four Degree Of Freedom Robot, Chloe Arluck Aug 2019

Approximate Free Space Construction And Maximum Clearance Path Planning For A Four Degree Of Freedom Robot, Chloe Arluck

Open Access Theses

We present an algorithm for constructing an inner approximation of the free space for a polyhedral robot with four degrees of freedom. The robot rotates about a fixed axis and translates in three dimensions with respect to a fixed polyhedral obstacle. We approximate the free space by subdividing the rotation dimension into short angle ranges, generating a three dimensional free space for each angle range, and constructing a graph for navigation in the four dimensional space. We also present an algorithm for path planning that is complete in the approximated space. The path planning algorithm produces paths that are guaranteed …


First-Time Experience In Owning A Dog Guide By Older Adults With Vision Loss, Kitsum Li, Jeffrey Kou, Yvonne Lam, Patricia Lyons, Susan Nguyen Aug 2019

First-Time Experience In Owning A Dog Guide By Older Adults With Vision Loss, Kitsum Li, Jeffrey Kou, Yvonne Lam, Patricia Lyons, Susan Nguyen

Occupational Therapy | Faculty Scholarship

Introduction: Dog guides were found to be effective in helping adults with vision loss navigate in the community and improve overall well-being. In spite of the vast amount of literature on pet therapy and dog companionship, limited study exists on older adult with vision loss experience of owning a dog guide. The purpose of this study is to explore the facilitators and barriers of first time owning and using a dog guide as experienced by older adults with vision loss.

Methods: Data were gathered among seven participants using open-ended semi-structured telephone interviews. Participants were asked to describe their experiences related …


Donna Dinaples V. Mrs Bpo Llc Aug 2019

Donna Dinaples V. Mrs Bpo Llc

2019 Decisions

USDC for the Western District of Pennsylvania


Negative Impacts Of The Beef Industry: Lab-Grown Meat, Stephanie Grass Aug 2019

Negative Impacts Of The Beef Industry: Lab-Grown Meat, Stephanie Grass

WRIT: Journal of First-Year Writing

The beef industry is harmful to the environment and human health and alternative solutions must be implemented in order to mitigate the effects of climate change. Water and grain are used in agriculture in abundance despite the negative environmental effects it causes. Cattle are the biggest contributors to greenhouse gas emissions in the sector, also contributing to climate change. Antibiotics are used in large quantities without regard to potential future consequences. One potential solution for this problem is lab-grown beef, which demands very little from the consumer and would take pressure off the environmental issues the beef industry creates. Lab-grown …