Digital Commons Network^™

Larger Genomes Linked To Slower Development And Loss Of Late-Developing Traits, Molly C. Womack, Marissa J. Metz, Kim L. Hoke

Biology Faculty Publications

Genome size varies widely among organisms and is known to affect vertebrate development, morphology, and physiology. In amphibians, genome size is hypothesized to contribute to loss of late-forming structures, although this hypothesis has mainly been discussed in salamanders. Here we estimated genome size for 22 anuran species and combined this novel dataset with existing genome size data for an additional 234 anuran species to determine whether larger genome size is associated with loss of a late-forming anuran sensory structure, the tympanic middle ear. We established that genome size is negatively correlated with development rate across 90 anuran species and found …

Applying Evidence-Based Research Principles In Review Design: Supporting Graduate And Faculty Research In The Life Sciences, Chris Fournier, Kate Ghezzi-Kopel

Upstate New York Science Librarians Conference

The reproducibility crisis in published scientific work is changing the way that research is designed and conducted. Librarians in academic institutions can play a key role in promoting improved adherence to evidence-based guidelines for performing literature reviews. The Cornell Systematic Review Team has developed a checklist, https://osf.io/2edg9/?pid=ezqpd, that can be used in research consultations as a conversation framework when assisting patrons with review design. This checklist is informed by widely accepted best practices for development of a sound systematic review protocol. Discussing this checklist with patrons promotes increased transparency, reduction of bias, and improved reproducibility of graduate student and …

Hogfish Neurocranium, Christopher Z. Lucero, Michael A. Terlizzi, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Volume Cxxxvii, Number 5, October 18, 2019, Lawrence University

The Lawrentian

No abstract provided.

Specific Effects Of Antitumor Active Norspermidine On The Structure And Function Of Dna, Takashi Nishio, Yuko Yoshikawa, Chwen-Yang Shew, Naoki Umezawa, Tsunehiko Higuchi, Kenichi Yoshikawa

Publications and Research

We compared the effects of trivalent polyamines, spermidine (SPD) and norspermidine (NSPD), a chemical homologue of SPD, on the structure of DNA and gene expression. The chemical structures of SPD and NSPD are different only with the number of methylene groups between amine groups,[N-3-N-4-N] and [N-3-N-3-N], respectively. SPD plays vital roles in cell function and survival, including in mammals. On the other hand, NSPD has antitumor activity and is found in some species of plants, bacteria and algae, but not in humans. We found that both polyamines exhibit biphasic effect; enhancement and inhibition on in vitro gene expression, where SPD …

October 18, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Design And Delivery Of Synthetic Mrna By A Peptide Nanoparticle, John H. Lockhart

USF Tampa Graduate Theses and Dissertations

The field of synthetic mRNA therapeutics is a rapidly expanding arm of gene therapies. The use of mRNA provides multiple benefits over viral or DNA vectors. synthetic mRNA vectors are immediately translated into protein after entering the cytoplasm of cells in contrast to DNA vectors that must first be transcribed to mRNA in the nucleus. This allows synthetic mRNA to produce a therapeutic protein in any cell type, including non-dividing cells. In addition, the non-replicative nature of mRNA means that insertional mutagenesis or generation of escape mutants is not a concern. However, the stimulation of innate immune responses by unmodified …

October 18, 2019, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Heat Shock Factor 1-Mediated Transcription Activation Of Omi/Htra2 Induces Myocardial Mitochondrial Apoptosis In The Aging Heart., Dan Liu, Linguo Wu, Ye Wu, Xin Wei, Wen Wang, Suli Zhang, Ming Yi, Jing Li, Huirong Liu, Xin-Liang Ma

Department of Emergency Medicine Faculty Papers

BACKGROUND: Increased cardiac apoptosis is a hallmark of the elderly, which in turn increases the risk for developing cardiac disease. The overexpression of Omi/HtrA2 mRNA and protein contributes to apoptosis in the aged heart. Heat shock factor 1 (HSF1) is a transcription factor that binds to the promoter of Omi/HtrA2 in the aging myocardium. However, whether HSF1 participates in cardiomyocyte apoptosis via transcriptional regulation of Omi/HtrA2 remains unclear. The present study was designed to investigate whether HSF1 plays a role in Omi/HtrA2 transcriptional regulation and myocardial apoptosis.

METHODS AND RESULTS: Assessment of the hearts of mice of different ages was …

Walking Research And Opportunities From The National Cancer Institute, David Berrigan

PSU Transportation Seminars

Lack of physical activity is well established as a modifiable risk factor for cancer at multiple sites. Because walking (and rolling) are among the most common forms of physical activity in the United States, the Division of Cancer Control and Population Sciences of the US National Cancer Institute has supported a range of data resources, methods research and development and funding opportunities related to physical activity and cancer control across the entire cancer control continuum. In this seminar, Dr. Berrigan will share about emerging results from the 2015 National Health Interview Survey Walking and Perceptions of the Walking Environment Module, …

Counseling With Deaf Clients: The Need For Culturally And Linguistically Sensitive Interventions, Paul Freedman

JADARA

Many counselors and therapists who work with culturally Deaf clients have had the unfortunate experience of trying to use what they consider to be an appropriate intervention, only to see it elicit a response of silence and puzzlement from the client. At other times the clinician may become creative and use an intervention that seems to propel the session forward. Why is it that certain types of interventions tend to work better with Deaf clients? Why is it that some interventions seem inappropriate? Are there certain types of interventions that are best suited for use within a visual/gestural mode of …

Cross Cultural Ethics In The Conduct Of Deafness Research, Robert Q. Pollard Jr.

JADARA

This paper argues for and illustrates the application of contemporary cross-cultural ethical principle sand practices in deafness research. The relevance of framing some deafness researchas cross-cultural is first explained. A gradient is defined where cultural bearing varies from low to high, depending on a study’s topic and design. It is concluded that scientists should employ contemporary cross-cultural ethical practices when their studies have cultural bearing. The evolution and nature of these special ethical practices are then detailed. They extend research protections beyond the individual participant to the host community as a collective entity. They address: relations with the heterogeneous host …

Point Of View/Article, Michael Tuceelll

JADARA

none

Boonshoft School Of Medicine Central Research Forum Program - 2019, Office Of Research Affairs, Boonshoft School Of Medicine

Central Research Forum

An 88 page program which includes a schedule and abstracts from the 2019 Central Research Forum held by the Boonshoft School of Medicine's Office of Research Affairs.

Spartan Daily, October 17, 2019, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2019

Volume 153, Issue 24

The Indiana Statesman, October 17, 2019, Indiana State University

Student Newspaper

Singer, songwriter Samuel Mason: A star in the making; Who's who in the mayoral debate; Breathalyzer for weed could be a ‘game changer’ for legalization efforts

Discarded: Exploring Material Stories And Movements Through Participatory, Public Art Interventions, Kira Hegeman

Journal of Social Theory in Art Education

Drawing on DeCerteau’s (1984) philosophy of tactics, which subvert dominant ways of being through creative appropriations of space and behavior, and New Materialist philosophies that offer vitality and agency to non-human objects (Barad, 2007; Bennett, 2004; 2010), this paper explores a three-part series of participatory, public art interventions related to waste, consumption and material relationships. The three installations were distinct but connected, situated in public spaces and corridors as a means of disrupting daily moments while encouraging moments of pause to be with discarded, material objects in playful and creative ways (de Certeau, 1984; Debord, 1956). With these installations we …

Full Issue, Number 50, Fall 2019

Intersections

No abstract provided.

The "V" Word: Different Dimensions Of Vocation In A Religiously Diverse Classroom, Martha E. Stortz

Intersections

No abstract provided.

The Vocation Of White People In A Racist Society, Caryn D. Riswold

Intersections

No abstract provided.

Functional Traits Explain Amphibian Distribution In The Brazilian Atlantic Forest, Ricardo Lourenço-De-Moraes, Felipe S. Campos, Rodrigo B. Ferreira, Karen H. Beard, Mirco Solé, Gustavo A. Llorente, Rogério P. Bastos

Ecology Center Publications

Aim: Species distributions are one of the most important ways to understand how communities interact through macroecological relationships. The functional abilities of a species, such as its plasticity in various environments, can determine its distribution and beta diversity patterns. In this study, we evaluate how functional traits influence the distribution of amphibians, and hypothesize which functional traits explain the current pattern of amphibian species composition in the Atlantic Forest.

Location: Atlantic Forest, Brazil.

Methods: Using potential distributions of Brazilian Atlantic Forest of amphibian species, we analysed the relative importance of abiotic factors and species functional traits in explaining species richness, …

Meet April Thompson, October's Staff Member Of The Month, Inside Ole Miss

University of Mississippi News

No abstract provided.

Superior Colliculus Lesions Lead To Disrupted Responses To Light In Diurnal Grass Rats (Arvicanthis Niloticus), Andrew J. Gall, Alyssa M. Goodwin, Ohanes S. Khacherian, Laura B. Teal

Faculty Publications

The circadian system regulates daily rhythms of physiology and behavior. Although extraordinary advances have been made to elucidate the brain mechanisms underlying the circadian system in nocturnal species, less is known in diurnal species. Recent studies have shown that retinorecipient brain areas such as the intergeniculate leaflet (IGL) and olivary pretectal nucleus (OPT) are critical for the display of normal patterns of daily activity in diurnal grass rats (Arvicanthis niloticus). Specifically, grass rats with IGL and OPT lesions respond to light in similar ways to intact nocturnal animals. Importantly, both the IGL and OPT project to one another …

New Minor Brings Nutrition Into The Kitchen, Sarah Schaier

UNH Today Archive

No abstract provided.

Compressive Sensing Inference Of Neuronal Network Connectivity In Balanced Neuronal Dynamics, Victor J. Barranca, D. Zhou

Mathematics & Statistics Faculty Works

Determining the structure of a network is of central importance to understanding its function in both neuroscience and applied mathematics. However, recovering the structural connectivity of neuronal networks remains a fundamental challenge both theoretically and experimentally. While neuronal networks operate in certain dynamical regimes, which may influence their connectivity reconstruction, there is widespread experimental evidence of a balanced neuronal operating state in which strong excitatory and inhibitory inputs are dynamically adjusted such that neuronal voltages primarily remain near resting potential. Utilizing the dynamics of model neurons in such a balanced regime in conjunction with the ubiquitous sparse connectivity structure of …

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for October 17-23, 2019. Vol. 114, No. 3.

A Newcomer's Guide To Functional Near Infrared Spectroscopy Experiments, Rand K. Almajidy, Kunal Mankodiya, Mohammadreza Abtahi, Ulrich G. Hofmann

Electrical, Computer, and Biomedical Engineering Faculty Publications

This review presents a practical primer for functional near-infrared spectroscopy (fNIRS) with respect to technology, experimentation, and analysis software. Its purpose is to jump-start interested practitioners considering utilizing a non-invasive, versatile, nevertheless challenging window into the brain using optical methods. We briefly recapitulate relevant anatomical and optical foundations and give a short historical overview. We describe competing types of illumination (trans-illumination, reflectance, and differential reflectance) and data collection methods (continuous wave, time domain and frequency domain). Basic components (light sources, detection, and recording components) of fNIRS systems are presented. Advantages and limitations of fNIRS techniques are offered, followed by a …

Investment Of Both Essential Fatty And Amino Acids To Immunity Varies Depending On Reproductive Stage, Taylor V. Pettit, R. John Pettit, Andrew M. Durso, Susannah S. French

Ecology Center Publications

Trade‐offs among the key life‐history traits of reproduction and immunity have been widely documented. However, the currency in use is not well‐understood. We investigated how reproducing female side‐blotched lizards, Uta stansburiana, allocate lipids versus proteins when given an immune challenge. We tested whether lizards would invest more in reproduction or immunity depending on reproductive stage. Females were given stable isotopes (¹⁵N‐leucine and ¹³C‐1‐palmitic acid), maintained on a regular diet and given either a cutaneous biopsy or a sham biopsy (control). Stable isotopes were monitored and analyzed in feces and uric acid, skin biopsies, eggs, and toe …

His House, Our House And Her House: A Filmic Place For Women, I Troiani

School of Art, Design and Architecture

The most famous architects in the world are, and have always been, men, although a growing number of women architects are beginning to gain international and public recognition. Architecture, more than some other types of professions, has moved slowly to accommodate its own increasing number of women practitioners (Fowler and Wilson 2004). This is in part because of its link to ‘a specific historical and cultural construction of masculinity and a masculinist vision of professional work’ (Davies 1996: 661) within what remains to be a maledominated construction industry. A UK report documenting women’s membership into the Chartered Institute of Building …

Kenyon Collegian - October 17, 2019

The Kenyon Collegian

No abstract provided.