Digital Commons Network^™

Bio-Mechanical Characterization Of Adherent Cell Layers With A Pdms Cantilever, Merrel Truly Holley

LSU Doctoral Dissertations

In the last few decades, the mechanical characteristics of human cells has been linked to many physiological processes and pathological conditions, illustrating the importance as effective biomarkers. Mounting research has shown the mechanical force between cells and the extracellular matrix (ECM) plays a vital role in cellular processes such as tissue homeostasis, wound healing, cancer metastasis, and the progression of various diseases. This mechanical force, or the force that a cell produces on its surroundings, is termed as the cellular traction force (CTF). Precise characterization of the CTF can expand our knowledge of these important cellular processes as well as …

Education In The Settler Colony: Displacement, Inequality, And Disappearance Via Charter Schools, David R. Fisher

USF Tampa Graduate Theses and Dissertations

The encroachment of market-based practices on public education has resulted in the creation of vouchers, charter schools, virtual schools, home schools, and other forms of educational choice. While there has always been choice in education in the United States for the wealthy and White, the current conception of school choice, in theory, allows equal access to education for all. Undergirding the neoliberal practice of school choice is a connection to a troubling past of capitalist oppression and settler colonialism. Like settler colonialism, the practice of school choice has resulted in the displacement of educators, families, and students, inequality between different …

The Role Of Secreted Proteases In Regulating Disease Progression In Staphylococcus Aureus, Brittney D. Gimza

USF Tampa Graduate Theses and Dissertations

Staphylococcus aureus is a highly successful pathogen capable of producing a wealth of virulence factors in the human host. Of note, ten extracellular proteases are produced alongside these virulence factors and play a multifaceted role during infection. They not only cleave host proteins to promote bacterial invasion, immune evasion and survival, but also control disease progression by modulating the stability of self-derived pathogenic determinants. The importance of the secreted proteases modulating virulence factor stability is evidenced by our groups previous finding that a protease-null strain has a substantially increased infectious capacity in a murine model of sepsis; resulting from the …

Development Of Α-Aa Peptides As Peptidomimetics For Antimicrobial Therapeutics And The Discovery Of Nanostructures, Sylvia E. Singh

USF Tampa Graduate Theses and Dissertations

For decades it has been convention to use antibiotics for the treatment of bacterial infections. Due to the overuse and misuse of these drugs, bacteria are becoming resistant to these treatments. This phenomenon has led to the search for alternative antibiotics, and in the study of Host Defense Peptides (HDPs). HDPs are the body’s innate immune response to infection. They are known to modulate immune system response and kills bacterial using various methods causing them to be less susceptible to bacterial resistance. The method by which we can mimic these biological peptides is called peptidomimetics. Various research shows the use …

Genealogies Of Queerness On The Modernist Stage: But, Where's The Performance?, Joseph Cermatori

Criticism

No abstract provided.

Viral Infections And Interferons In The Development Of Obesity, Yun Tian, Jordan Jennings, Yuanying Gong, Yongming Sang

Agricultural and Environmental Sciences Faculty Research

Obesity is now a prevalent disease worldwide and has a multi-factorial etiology. Several viruses or virus-like agents including members of adenoviridae, herpesviridae, slow virus (prion), and hepatitides, have been associated with obesity; meanwhile obese patients are shown to be more susceptible to viral infections such as during influenza and dengue epidemics. We examined the co-factorial role of viral infections, particularly of the persistent cases, in synergy with high-fat diet in induction of obesity. Antiviral interferons (IFNs), as key immune regulators against viral infections and in autoimmunity, emerge to be a pivotal player in the regulation of adipogenesis. In this review, …

Method Of Predicting Obesity Comprising Measuring Neurotensin, B. Mark Evers, Jing Li, Paul Dobner, Olle Melander

Surgery Faculty Patents

The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. The presently disclosed subject matter further relates to a method of preventing and/or treating obesity in a subject in need thereof by administering to the subject an effective amount of an agent …

Ua12/2/1 College Heights Herald, Vol. 95, No. 12, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Lamb, Cassidy & Lily Burris. College Towns Go Blue, Aiding Andy Beshear – Elections
• Dobbs, Jack. Double-Check – Matt Bevin
• Rexing, Brody. WKU Retention, Out-of-State Enrollment Improves
• Nutter, Abbey & Cassady Lamb. New Cash Registers Reduce Waits at On-campus Restaurants
• Stack, Madalyn. Editorial Cartoon re: Matt Bevin Losing
• Just Give It Up – Matt Bevin
• Heath, Esther. Stressful Relief – Kart Racing
• Tolbert, Eleanor. GypsyMoon Marketplace Increases Draw, Builds Tradition
• Button, Gabby. Style for All – Paige McKinney, Trash Queen
• Latture, Katelyn. Pop-up Doughnut Shop …

The Utah Statesman, November 12, 2019, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Indiana Statesman, November 12, 2019, Indiana State University

Student Newspaper

An emotional sendoff as Tiarra Taylor heads to the Miss America Pageant; Veteran’s Day: A day of remembrance and honor; Natural con for natural beauty; ISU presents 2019 inclusive excellence awards

The Current Volume 30 : Issue 12, Nova Southeastern University

Student Newspapers

No abstract provided.

The State Of Utah, Plaintiff/ Appellee V. Wayne Lee Burr & Blaine Lynn Burr , Defendant/ Appellant : Brief Of Appellee, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

Appeal from the Sixth Judicial District, Honorable Marvin D. Bagley presiding

Christian Poetry Themes In My Life, Kayla Viaud

Graduate Student Dissertations, Theses, Capstones, and Portfolios

My artwork is inspired by the Christian poetry books, Psalms and Proverbs. Throughout my work, I hope viewers will be inspired, gain wisdom, and reflect on life. The color themes are bright - yellows, oranges, and pink. With these works see my bright bubbly Christian personality on display.

Sylvilagus Audubonii And Lepus Californicus Home Range Sizes In The Chihuahuan Desert, Robert L. Harrison

Western North American Naturalist

Knowledge of a species’ home range size is useful for numerous areas of study, including body-mass scaling, metabolic requirements, and conservation. Notably lacking are home range size estimates from desert habitats for 2 common mammals, Sylvilagus audubonii and Lepus californicus. I estimated daytime, nighttime, and 24-h home range sizes using telemetry in the Chihuahuan Desert of south central New Mexico. For both species, estimates were larger in nighttime than in daytime, and estimates for S. audubonii were larger for males than for females. I found no evidence for home range “cores.”


El conocer el tamaño del ámbito hogareño de una …

Food Habits Of Coyotes (Canis Latrans) In The Valles Caldera National Preserve, New Mexico, Suzanne J. Gifford, Eric M. Gese, Robert R. Parmenter

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife managers needed to understand coyote (Canis latrans) ecology in order to develop management plans on the nascent Valles Caldera National Preserve in northern New Mexico. Managers concerned about low elk (Cervus elaphus) recruitment had observed an increase in sightings of coyotes and observations of coyote predation on elk calves. Our objective was to identify and quantify coyote diet, and assess the temporal variation in coyote diet on the Valles Caldera National Preserve, particularly as related to elk calf consumption. We examined coyote food habits using 1,385 scats analyzed monthly from May 2005 to November 2008. …

The Prospector, November 12, 2019, Utep Student Publications

The Prospector

Headline: International Issue: Border Tuner

Genome-Wide Variation In Potyviruses, Deepti Nigam, Katherine Latourrette, Pedro F.N. Souza, Hernan Garcia Ruiz

Nebraska Center for Virology: Faculty Publications

Potyviruses (family Potyviridae, genus Potyvirus) are the result of an initial radiation event that occurred 6,600 years ago. The genus currently consists of 167 species that infect monocots or dicots, including domesticated and wild plants. Potyviruses are transmitted in a non-persistent way by more than 200 species of aphids. As indicated by their wide host range, worldwide distribution, and diversity of their vectors, potyviruses have an outstanding capacity to adapt to new hosts and environments. However, factors that confer adaptability are poorly understood. Viral RNA-dependent RNA polymerases introduce nucleotide substitutions that generate genetic diversity. We hypothesized that selection imposed by …

Constructed Action In American Sign Language: A Look At Second Language Learners In A Second Modality, Kim B. Kurz, Kellie Mullaney, Corrine Occhino

Articles

Constructed action is a cover term used in signed language linguistics to describe multi-functional constructions which encode perspective-taking and viewpoint. Within constructed action, viewpoint constructions serve to create discourse coherence by allowing signers to share perspectives and psychological states. Character, observer, and blended viewpoint constructions have been well documented in signed language literature in Deaf signers. However, little is known about hearing second language learners’ use of constructed action or about the acquisition and use of viewpoint constructions. We investigate the acquisition of viewpoint constructions in 11 college students acquiring American Sign Language (ASL) as a second language in a …

Seeing Like A Citizen : Decolonization, Development, And The Making Of Kenya, 1945–1980, Kara Moskowitz

Ohio University Press Open Access Books

In Seeing Like a Citizen, Kara Moskowitz approaches Kenya’s late colonial and early postcolonial eras as a single period of political, economic, and social transition. In focusing on rural Kenyans—the vast majority of the populace and the main targets of development interventions—as they actively sought access to aid, she offers new insights into the texture of political life in decolonizing Kenya and the early postcolonial world.

Using multisited archival sources and oral histories focused on the western Rift Valley, Seeing Like a Citizen makes three fundamental contributions to our understanding of African and Kenyan history. First, it challenges the widely …

Africa Every Day : Fun, Leisure, And Expressive Culture On The Continent, Oluwakemi M. Balogun, Lisa Gilman, Melissa Graboyes, Habib Iddrisu

Ohio University Press Open Access Books

Africa Every Day presents an exuberant, thoughtful, and necessary counterpoint to the prevailing emphasis in introductory African studies classes on war, poverty, corruption, disease, and human rights violations on the continent. These challenges are real and deserve sustained attention, but this volume shows that adverse conditions do not prevent people from making music, falling in love, playing sports, participating in festivals, writing blogs, telling jokes, making videos, playing games, eating delicious food, and finding pleasure in their daily lives.
Across seven sections—Celebrations and Rites of Passage; Socializing and Friendship; Love, Sex, and Marriage; Sports and Recreation; Performance, Language, and Creativity; …

A Novel Cytokine Response Modulatory Function Of Mek Inhibitors Mediates Therapeutic Efficacy, Mengyu Xie

USF Tampa Graduate Theses and Dissertations

Despite the recent success of immune-checkpoint blockade therapy for late-stage non-small cell lung cancer (NSCLC), lung cancer is still the leading cause of cancer deaths worldwide. One of the most important characteristics of lung cancer in therapeutic decision-making are the targetable molecules, including EGFR, ALK, BRAF, and MEK. The excitement of immune-checkpoint blockade therapy has triggered concerted efforts that focus on exploring combinations of immune checkpoint therapy with other approved therapeutic regimens aiming at further augmenting positive outcomes and survival. However, the lack of understanding of underlying mechanisms and evidence-based clinical testing has hindered the progress to a cure. Hence, …

Cactus-Based Mucilage As A Natural Dispersant For Crude Oil Spills, Fei Guo

USF Tampa Graduate Theses and Dissertations

Oil spills are a critical threat to the marine environment, and the spilled oil as a source of pollution can have long-term adverse effects on the marine ecosystem. Traditional mechanical clean-up operations have apparent advantages for dealing with small and medium-scale oil spills. For large-scale oil spills, dispersants are a practical and minimally influential approach to the environment. As the dispersant components are iteratively updated, dispersants become more efficient and safer. However, the toxicity of the dispersants remains a significant impediment to their application. An efficient and non-toxic dispersant is increasingly becoming a requirement.

The cactus mucilage extracts studied in …

Electrification Ionization: Fundamentals And Applications, Bijay Kumar Banstola

LSU Doctoral Dissertations

Electrification ionization is a method to produce ions from solid samples by charge separation. This separation of charge can be enhanced by organic molecules known as matrix compounds to produce highly charged molecules. In this research, new methods were developed for the application of electrification ionization for surface analysis and the ionization mechanism was investigated. First, an electrification ionization matrix was used for tissue imaging using laser ablation. A two-component matrix of 2-nitrophloroglucinol and silica nanoparticles was found to increase the number of multiply charged ions from the tissue. Images of mouse brain with multiply charged ions were obtained. In …

Transgenic Control Of Aflatoxin Contamination In Maize Through Host-Induced Gene Silencing Targeting Aspergillus Flavus Genes Encoding Polygalacturonase (P2c) And Versicolorin Dehydrogenase (Aflm), Yenjit Raruang

LSU Doctoral Dissertations

Maize (Zea mays L.) is susceptible to Aspergillus flavus infection and subsequent contamination with aflatoxins, the most potent naturally produced carcinogenic secondary metabolites. Here, the A. flavus gene aflM encoding the versicolorin dehydrogenase in aflatoxin biosynthesis and the p2c gene encoding the polygalacturonase that is involved in infection were selected as targets for suppression through host induced gene silencing (HIGS). A HIGS vector targeting these genes was constructed and introduced into immature B104 maize embryos. Thirteen out of fifteen p2c transformation events and six out of seven aflM events were confirmed positive by PCR. Kernels containing the p2c gene …

Environmental Explorations: Integrating Project-Based Learning And Civic Engagement Through An Afterschool Program, Rachel Farmer, Nakayla Greene, Kristen H. Perry, Cindy Jong

Journal of Educational Research and Practice

This study examined the Community Super Investigators Club, through which we aimed to apply mathematics and literacy skills by using project-based learning (PBL) to investigate elementary students’ interest in learning how to improve the environment for animals. PBL is a teaching method used to improve critical thinking skills around a project that is based on students’ questions. The study used a mixed-method design to examine the following research questions: How do students engage in PBL on topics relevant to their community in an afterschool club? How can critical math and literacy skills be integrated with community engagement? How did the …

36th Annual Reception Bibliography, 2018-2019, Leonard H. Axe Library

Bibliographies

Since 1984, Leonard H. Axe Library at Pittsburg State University has honored book authors and other creators for their outstanding scholarship and contributions to their fields.

Cseas Weekly Bulletin (November 11, 2019), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

The Relationship Between Length Of Community Tenure And Residents’ Volunteering At Community Events: Results From The Metro Atlanta Speaks Survey, Ramesh Ghimire, Jim Skinner

Journal of Rural Social Sciences

Volunteering at community events could be associated with length of community tenure as residents with longer years of “tenure” might have a greater sense of community belonging, greater social capital (e.g. social networks and trust), and greater familiarity with regional cultures, compared to new residents. Using the Metro Atlanta Speaks survey conducted in 2015 and 2016, this study finds that residents’ volunteering at community events is significantly and positively associated with their length of community tenure in metro Atlanta counties. Other sociodemographic characteristics, such as age, gender, education, income, and children in the household also significantly influence residents’ volunteering at …

Suppressing Mir-21 Activity In Tumor-Associated Macrophages Promotes An Antitumor Immune Response, Mahnaz Sahraei, Balkrishna Chaube, Yuting Liu, Jonathan Sun, Alanna Kaplan, Nathan L. Price, Wen Ding, Stanley Oyaghire, Rolando Garcia-Milian, Sameet Mehta, Yana Reshetnyak, Raman Bahal, Paolo Fiorina, Peter M. Glazer, David L. Rimm, Carlos Fernandez-Hernando, Yajaira Suarez

Physics Faculty Publications

microRNA-21 (miR-21) is the most commonly upregulated miRNA in solid tumors. This cancer-associated microRNA (oncomiR) regulates various downstream effectors associated with tumor pathogenesis during all stages of carcinogenesis. In this study, we analyzed the function of miR-21 in noncancer cells of the tumor microenvironment to further evaluate its contribution to tumor progression. We report that the expression of miR-21 in cells of the tumor immune infiltrate, and in particular in macrophages, was responsible for promoting tumor growth. Absence of miR-21 expression in tumor- associated macrophages (TAMs), caused a global rewiring of their transcriptional regulatory network that was skewed toward a …

Guide To Ms680 Carol Price Miller Papers, Katherine Espinoza

Finding Aids

Carol Price Miller is a writer and advocate for the arts, history, education, and the welfare of animals. Her papers date 1981 - 2007. Types of records include a newspaper, papers written by Carol Price Miller, a photograph, and materials from a conference. Many of the records primarily concern topics about education and writing, as they pertain to the border and people of color, as well as works on the Southwest and El Paso art and artists.