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2019

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Longitudinal Study Of Humoral Immunity To Bovine Coronavirus, Virus Shedding, And Treatment For Bovine Respiratory Disease In Pre-Weaned Beef Calves, Aspen M. Workman, Larry A. Kuehn, Tara G. Mcdaneld, Michael L. Clawson, John Dustin Loy Jan 2019

Longitudinal Study Of Humoral Immunity To Bovine Coronavirus, Virus Shedding, And Treatment For Bovine Respiratory Disease In Pre-Weaned Beef Calves, Aspen M. Workman, Larry A. Kuehn, Tara G. Mcdaneld, Michael L. Clawson, John Dustin Loy

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: Bovine coronavirus (BCV) is associated with respiratory infections in cattle of all ages; however, a temporal study to evaluate the effect of BCV immunity on virus shedding and bovine respiratory disease (BRD) incidence in pre-weaned beef calves has not been reported. Thus, we report here a prospective study in three herds of crossbred beef calves (n = 817) with endemic BCV. Serial blood samples for measurement of serum anti-BCV antibody titers and nasal swabs for detection of BCV and other common viral and bacterial BRD pathogens were collected from all calves or subsets of calves at predetermined …


Capacity To Elicit Cytotoxic Cd8 T Cell Activity Against Mycobacterium Avium Subsp. Paratuberculosis Is Retained In A Vaccine Candidate 35 Kda Peptide Modified For Expression In Mammalian Cells, Valentina Franceschi, Asmaa H. Mahmoud, Gaber S. Abdellrazeq, Giulia Tebaldi, Francesca Macchi, Luca Russo, Lindsay M. Fry, Mahmoud M. Elnaggar, John Bannantine, Kun-Taek Park, Victoria Hulubei, Sandro Cavirani, William C. Davis, Gaetano Donofrio Jan 2019

Capacity To Elicit Cytotoxic Cd8 T Cell Activity Against Mycobacterium Avium Subsp. Paratuberculosis Is Retained In A Vaccine Candidate 35 Kda Peptide Modified For Expression In Mammalian Cells, Valentina Franceschi, Asmaa H. Mahmoud, Gaber S. Abdellrazeq, Giulia Tebaldi, Francesca Macchi, Luca Russo, Lindsay M. Fry, Mahmoud M. Elnaggar, John Bannantine, Kun-Taek Park, Victoria Hulubei, Sandro Cavirani, William C. Davis, Gaetano Donofrio

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Studies focused on development of an attenuated vaccine against Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of paratuberculosis (Ptb) in cattle and other species, revealed that deletion of relA, a global gene regulator, abrogates the ability of Map to establish a persistent infection. In the absence of relA, cattle develop CD8 cytotoxic T cells (CTL) with the ability to kill intracellular bacteria. Analysis of the recall response to a relA mutant, Map/􏰀relA, with cells from a vaccinated steer demonstrated that a 35-kDa membrane peptide (MMP) is one of the targets of the response. This observation suggested that it might …


Phenotypes Of Macrophages Present In The Intestine Are Impacted By Stage Of Disease In Cattle Naturally Infected With Mycobacterium Avium Subsp. Paratuberculosis, Caitlin J. Jenvey, Adrienne L. Shircliff, J. P. Bannantine, Judith R. Stabel Jan 2019

Phenotypes Of Macrophages Present In The Intestine Are Impacted By Stage Of Disease In Cattle Naturally Infected With Mycobacterium Avium Subsp. Paratuberculosis, Caitlin J. Jenvey, Adrienne L. Shircliff, J. P. Bannantine, Judith R. Stabel

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Macrophages play an important role in the host immune response to Mycobacterium avium subsp. paratuberculosis (MAP) infection, however, MAP is able to disrupt normal macro- phage functions to avoid destruction. It is unclear whether the phenotypes of macrophages present in the target tissue play a role in the inability to clear MAP infection. The aim of this study was to identify macrophage phenotypes (host defense or resolution and repair) present within the bovine ileum of naturally infected cattle, as well as to ascertain abundance of each macrophage phenotype present during different stages of MAP infection. Immunofluo- rescent (IF) labeling was …


Predicting Spatial Risk Of Wolf-Cattle Encounters On Rugged And Extensive Grazing Lands, Patrick R. Clark, Joe Chigbrow, Douglas E. Johnson, John Williams, Larry L. Larson, Tyanne Roland Jan 2019

Predicting Spatial Risk Of Wolf-Cattle Encounters On Rugged And Extensive Grazing Lands, Patrick R. Clark, Joe Chigbrow, Douglas E. Johnson, John Williams, Larry L. Larson, Tyanne Roland

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Cattle grazing lands in the mountainous western United States are rugged, complex, and extensive. Terrain, vegetation, and other landscape features vary greatly across space. Risk of wolf-cattle encounters and potential for depredation loss certainly differ spatially as consequence of this variability. Yet, our understanding of this spatial risk is quite poor and this knowledge gap severely hampers our abilities to manage wolf-livestock interactions and mitigate conflicts. During 2009-2011, a research study was conducted at four study areas (USFS cattle grazing allotments) in western Idaho to evaluate and predict risk of wolf-cattle encounters. Each year, a random sample of 10 lactating …


Characterization Of Ethanol Extracted Cell Wall Components Of Mycobacterium Avium Subsp. Paratuberculosis, John P. Bannantinea, Ashutosh Wadhwa, Judith R. Stabel, Shigetoshi Eda Jan 2019

Characterization Of Ethanol Extracted Cell Wall Components Of Mycobacterium Avium Subsp. Paratuberculosis, John P. Bannantinea, Ashutosh Wadhwa, Judith R. Stabel, Shigetoshi Eda

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Antigens extracted using ethanol (EtOH) and incorporated in the EtOH vortex ELISA (EVELISA) test have previously shown high specificity and sensitivity for detecting Mycobacterium avium subspecies paratuberculosis (Map) and M. bovis infections in cattle. The objective of this study is to define the components present in the EtOH extract. We show that this extract is composed of lipid, carbohydrate, and proteins on the surface of the bacilli, and that EtOH removes the outer layer structure of Map which comprise these elements. To identify proteins, polyclonal antibodies to the EtOH prep were produced and used to screen a Map genomic expression …


Reconceptualizing Criminal Justice Reform For Offenders With Serious Mental Illness, E. Lea Johnston Jan 2019

Reconceptualizing Criminal Justice Reform For Offenders With Serious Mental Illness, E. Lea Johnston

UF Law Faculty Publications

Roughly 14% of male inmates and 31% of female inmates suffer from one or more serious mental illnesses, such as schizophrenia, bipolar disorder, and major depressive disorder. Policymakers and the public widely ascribe the overrepresentation of offenders with serious mental illness in the justice system to the “criminalization” of the symptoms of this afflicted population. The criminalization theory posits that the criminal justice system has served as the primary agent of social control over symptomatic individuals since the closure of state psychiatric hospitals in the 1950s and the tightening of civil commitment laws. The theory identifies untreated mental illness as …


Law School Rules, Regulations And Policies, And Orientation Guide, 2019-2020, Suffolk University Law School Jan 2019

Law School Rules, Regulations And Policies, And Orientation Guide, 2019-2020, Suffolk University Law School

Suffolk University Law School Academic Catalogs

No abstract provided.


"Scientific Inference" Vs. "Legal Reasoning"? Not So Fast! ¿"Inferencia Cientifíca" Vs."Razonamiento Jurídico"? -- No Tan Rápido!, Susan Haack Jan 2019

"Scientific Inference" Vs. "Legal Reasoning"? Not So Fast! ¿"Inferencia Cientifíca" Vs."Razonamiento Jurídico"? -- No Tan Rápido!, Susan Haack

Articles

No abstract provided.


Scoot Over: How Electric Scooters Violate The Ada And What Cities Can Do To Maintain Title Ii Compliance, Jo Ann Mazoch Jan 2019

Scoot Over: How Electric Scooters Violate The Ada And What Cities Can Do To Maintain Title Ii Compliance, Jo Ann Mazoch

SMU Law Review

No abstract provided.


The Blockchain Paradox: Almost Always Reliable, Almost Never Admissible, J. Collin Spring Jan 2019

The Blockchain Paradox: Almost Always Reliable, Almost Never Admissible, J. Collin Spring

SMU Law Review

No abstract provided.


Wellness Programming For Men In Long-Term Care, Katie Hautman, Ashley Heinze Jan 2019

Wellness Programming For Men In Long-Term Care, Katie Hautman, Ashley Heinze

Occupational Therapy Capstones

Introduction: The purpose of this project was to develop a wellness guide for staff to implement in long-term care (LTC), to increase participation of meaningful activities and well-being for male residents of all abilities, both physically and psychosocially.

Methodology: A literature review was conducted to understand the need for activities of male residents in LTC. Sources included: online databases, textbooks, and government websites. The Canadian Model of Occupational Performance and Engagement (CMOPE) was selected to direct the development of the program guide. The CMOP-E promotes engagement in occupations and enablement of occupational performance, both of which are important for male …


Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman Jan 2019

Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman

Oral History Posters

With the high incidence of Lyme disease in the endemic areas of North America, it is important to appropriately diagnosis and treat this condition to prevent post treatment Lyme disease syndrome (PTLDS).

Background information regarding Lyme disease is given. The purpose of this research is to discuss the treatment options available for those patients that fit the case definition of PTLDS. A literature review was conducted using several different electronic databases finding peer reviewed research articles pertaining to the treatment options available for PTLDS. Extended antibiotic use is shown to be not beneficial in most cases. Alternative treatment options listed …


The Use Of Dehydroepiandrosterone For Treatment Of Depression, Bryan Tipton Jan 2019

The Use Of Dehydroepiandrosterone For Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Papers

Dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) are important pre-hormones that also have direct neurohormonal effects on the central nervous system. Over the last twenty years, data have revealed that serum DHEA peaks in a person’s mid-20s and steadily declines throughout their lifetime. In addition, women tend to have lower values than men. This is of note because lower serum values tend to be correlated with increased risk of depression, worse depressive symptoms, and increased risk of relapse into depression. A review of literature concerning DHEA’s age related values, its association with depression, and its use in the treatment of …


Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman Jan 2019

Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman

Physician Assistant Scholarly Project Posters

With the high incidence of Lyme disease in the endemic areas of North America, it is important to appropriately diagnosis and treat this condition to prevent post treatment Lyme disease syndrome (PTLDS). Background information regarding Lyme disease is given. The purpose of this research is to discuss the treatment options available for those patients that fit the case definition of PTLDS. A literature review was conducted using several different electronic databases finding peer reviewed research articles pertaining to the treatment options available for PTLDS. Extended antibiotic use is shown to be not beneficial in most cases. Alternative treatment options listed …


Winter 2019, Gla Glq Jan 2019

Winter 2019, Gla Glq

Georgia Library Quarterly

No abstract provided.


Barefoot Training: Effects On Emg Activity Of Gluteus Medius And Tensor Fascia Latae In Habitually Shod Runners, Tom Linner, Casey Murphy, Jeremy O'Keefe Jan 2019

Barefoot Training: Effects On Emg Activity Of Gluteus Medius And Tensor Fascia Latae In Habitually Shod Runners, Tom Linner, Casey Murphy, Jeremy O'Keefe

Physical Therapy Scholarly Projects

Purpose/Hypothesis: Running has been a common practice in humans since the species’ dawn. Due to its relative ease and low cost, running continues to be one of the most popular forms of exercise today. Although running provides many benefits such as disease prevention, injury prevalence in running is high. The trend of minimalist shoes and barefoot training has gained popularity over the decade as a return to a more natural form of running. Some researcher hypothesize that barefoot running can reduce injury rate by changing the biomechanics of the runner. In this study we propose a different hypothesis: barefoot running …


Fast Charging Technique For Lithium-Ion Cell, Shabaz Khan Jan 2019

Fast Charging Technique For Lithium-Ion Cell, Shabaz Khan

Theses and Dissertations

Climate change is a big concern among the people. Day by day people are trying to increase the use of the sustainable energy in every sector of their life. Like other sectors, transportation sector manufacturers are beginning to shifting from fossil fuels based models to electric models. Manufacturers are trying to introduce electrified models from bicycles to cars. For energy storage, these electrified models are highly dependent on the battery. Lithium-ion cells have a high energy density, no memory effect, long cycle life and low self discharge quality, and are therefor highly used from portable electronics to electric vehicles everywhere. …


The Evaluation Of Pathogen Survival In Dry Cured Charcuterie Style Sausages, Jennifer Michelle Mcneil Jan 2019

The Evaluation Of Pathogen Survival In Dry Cured Charcuterie Style Sausages, Jennifer Michelle Mcneil

Theses and Dissertations--Animal and Food Sciences

The objective of this study was to evaluate the survival of non-O157:H7 STEC, Salmonella spp., and S. aureus in dry fermented sausages. Chorizo and Landjager sausages were inoculated with individual bacterial cocktails and stuffed into natural casings. Temperature, relative humidity, pH, and water activity were monitored through fermentation, drying, and storage. Bacterial counts were determined by serial dilution and plated in triplicates on selective media. Plates were incubated at 37°C for 24 hours and colony forming units per gram (CFU/g) were observed.

Results of the first study validate that contaminated raw materials contribute to pathogen survival and background bacteria outcompeted …


Effects Of Yeast-Derived Microbial Protein On Transition Dairy Cow Health And Performance, Gustavo Mazon Correa Alves Jan 2019

Effects Of Yeast-Derived Microbial Protein On Transition Dairy Cow Health And Performance, Gustavo Mazon Correa Alves

Theses and Dissertations--Animal and Food Sciences

The transition period for dairy cows is defined as the three weeks pre and postpartum. During the transition period, dairy cows experience a myriad of metabolic, managerial, and nutritional requirement changes. These changes lead to stress and increased susceptibility to diseases which can negatively affect lactational performance in the short and long term. However, dietary amino acid availability can have a dramatic impact on the health and performance of dairy cows around parturition. Thus, the objective of the thesis was to evaluate the effects of supplementing yeast-derived microbial protein, as an alternative protein source for dairy cows during the transition …


Long-Term Effects Of Different Fat Sources And Vitamin E Supplementation On Growth Performance, Antioxidant Status, Carcass Characteristics, Meat Quality, And Immune Capacity Of Pigs With Heavy Slaughter Weight Up To 150 Kg, Ding Wang Jan 2019

Long-Term Effects Of Different Fat Sources And Vitamin E Supplementation On Growth Performance, Antioxidant Status, Carcass Characteristics, Meat Quality, And Immune Capacity Of Pigs With Heavy Slaughter Weight Up To 150 Kg, Ding Wang

Theses and Dissertations--Animal and Food Sciences

Two experiments were used to evaluate the potential interaction of fat source and vitamin E (VE) in heavy slaughter weight pigs. In Experiment 1, a total of 64 individually-fed pigs (28.41 ± 0.83 kg) were randomly assigned to 8 dietary treatments in a 4×2 factorial arrangement. Fat treatments included cornstarch (CS), tallow (TW), corn-oil (CO), and coconut-oil (CN). VE treatments were dietary α-tocopheryl acetate (ATA) at 11 and 200 ppm. In Experiment 2, a total of 72 individually fed pigs (28.55 ± 1.16 kg) were randomly assigned to 12 dietary treatments in a 2 × 6 factorial arrangement. Fat treatments …


Metabolizable Energy Determination In Broiler Chickens, Andrew E. Dunaway Jan 2019

Metabolizable Energy Determination In Broiler Chickens, Andrew E. Dunaway

Theses and Dissertations--Animal and Food Sciences

Feed accounts for the highest cost associated in poultry production, with energy-containing feedstuffs being the most expensive portion of the cost of feeding. The increasing demand for poultry meat gives reason to determine accurate apparent metabolizable energy (AME) values for various feedstuff through measuring energy utilization in the birds. The adaptation length of birds fed an experimental diet may affect the determined AME value due to the diet matrix and physiochemical properties of the feedstuff. Therefore, the objective of this thesis was to evaluate a select group of energy-containing feedstuff with different diets and with factors such as coccidia challenge …


Thermal, Interfacial, And Application Properties Of Pea Protein Modified With High Intensity Ultrasound, Aeneas Koosis Jan 2019

Thermal, Interfacial, And Application Properties Of Pea Protein Modified With High Intensity Ultrasound, Aeneas Koosis

Theses and Dissertations--Animal and Food Sciences

The overall objective of the study was to investigate different food ingredient conditions and ultrasound treatment on pea protein in terms of surface morphology and thermal characteristics. The motivation of this work was based on previous studies focusing on non-chemical physical modifications of plant proteins and the increasing demand for functional alternative proteins.

Ultrasonication time and amplitude, pH, protein concentration, and salt concentration all influenced the thermal and interfacial properties of pea protein. Ultrasound treatment altered the quaternary and tertiary structure of the storage protein and disrupted non-covalent bonds. The structural altercations and a reduction in particle size led to …


Evaluating Costs Associated With Management Decisions Of Replacement Dairy Heifers And Their Impact On The Total Rearing Investment, Anna Catherine Hawkins Jan 2019

Evaluating Costs Associated With Management Decisions Of Replacement Dairy Heifers And Their Impact On The Total Rearing Investment, Anna Catherine Hawkins

Theses and Dissertations--Animal and Food Sciences

Replacement heifer rearing is critical for the future of the dairy operation, especially to improve genetic merit and maintain herd size. A replacement heifer from the day she is born to the day she calves herself is generally a 2-year investment without potential income. A myriad of options exists on how to manage, fed, and ultimately raise replacement heifers. This study quantifies the costs associated with replacement heifer management decisions from birth to calving related to housing, labor, feed and health. The heifer rearing period can be broken into pre and post weaning sections to allow for more understanding the …


Evaluation Of Current And Emerging Techniques For Measuring Eggshell Integrity Of The Domestic Fowl, Lauren Wood Nolan Jan 2019

Evaluation Of Current And Emerging Techniques For Measuring Eggshell Integrity Of The Domestic Fowl, Lauren Wood Nolan

Theses and Dissertations--Animal and Food Sciences

This dissertation is an investigation into the effect of different zinc sources and levels on eggshell quality and microstructure, as well as keel bone damage. Eggshell function is two-fold; eggshells function to protect the developing embryo, as well as act as a barrier against bacterial penetration, optimizing food safety of the egg for human consumption (Mabe et. Al., 2003). Two small trials were conducted in order to determine differences in eggshell microstructure of eggs produced from hens at peak lay (26 weeks of age) and at the end of lay (88 weeks of age). Two groups of hens were fed …


Developmental Changes In The Pig From Birth To 42 Days Post-Weaning (1.5 – 25 Kilograms Bodyweight), Sarah K. Elefson Jan 2019

Developmental Changes In The Pig From Birth To 42 Days Post-Weaning (1.5 – 25 Kilograms Bodyweight), Sarah K. Elefson

Theses and Dissertations--Animal and Food Sciences

This study evaluated the changes in body composition, glycogen tissue reserves, visceral organ growth, and small intestine morphology in the young pig. A total of 96 crossbred pigs were euthanized at birth (pre-suckle), days 1, 2, 3, 5, 7, 14 postpartum, weaning at day 21, and days 1, 2, 3, 5, 7, 14, 28, and 42 post-weaning. Body composition of the pig had increasing dry matter and fat, decreasing ash, calcium and phosphorus, and relatively static protein percentage over the course of the study. Liver and muscle glycogen was greatest at birth. Following birth and weaning there was a distinct …


Crossing The Line: Techniques Of Closing Argument That Are Out Of Bounds In Criminal Trials, Blake R. Mills Jan 2019

Crossing The Line: Techniques Of Closing Argument That Are Out Of Bounds In Criminal Trials, Blake R. Mills

University of Arkansas at Little Rock Law Review

No abstract provided.


Wearable Devices For Single Cell Sensing And Transfection, Lingqian Chang, Yu-Chieh Wang, Faheem Ershad, Ruiguo Yang, Cunjiang Yu, Yubo Fan Jan 2019

Wearable Devices For Single Cell Sensing And Transfection, Lingqian Chang, Yu-Chieh Wang, Faheem Ershad, Ruiguo Yang, Cunjiang Yu, Yubo Fan

Department of Mechanical and Materials Engineering: Faculty Publications

Transdermal drug delivery systems have been successful for decades. Now these devices can be further scaled down, and their applications have been extended to wide selections of cargo, ranging from natural molecules (e.g., insulin and glucose) to bioengineered molecules (e.g., nanoparticles and vaccines). Some emerging nanopatches show promise for precise single-cell gene transfection in vivo and have advantages over conventional tools in terms of delivery efficiency, safety, and controllability of delivered dose. In this review, we discuss recent technical advances in wearable micro/nano devices with unique capabilities or potential for single-cell biosensing and transfection in the skin or other organs, …


The “Uncanny Valley” And The Verisimilitude Of Sexual Offenders–Part I: An “Ethorobotic” Perspective, Michael T. Flannery Jan 2019

The “Uncanny Valley” And The Verisimilitude Of Sexual Offenders–Part I: An “Ethorobotic” Perspective, Michael T. Flannery

Law Faculty Scholarship

No abstract provided.


Raven’S Work In Tlingit Ethno-Geography, Thomas F. Thornton, Douglas Deur, Bert Adams Jan 2019

Raven’S Work In Tlingit Ethno-Geography, Thomas F. Thornton, Douglas Deur, Bert Adams

Anthropology Faculty Publications and Presentations

This is a chapter in Language and Toponymy in Alaska and Beyond: Papers in Honor of James Kari.

Book description:
It is difficult to imagine place names research in Alaska without the work of James Kari. Through his tireless field work and advocacy, Dr. Kari has collaborated with speakers of all of Alaska’s Dene languages to help build a comprehensive record of Dene geographic knowledge. When Jim came to Alaska in 1972, the documentation of Dene languages was fragmentary at best, and the only records of Native place names were those found inaccurately spelled on maps and gazetteers. Now …


How People With Multiple Sclerosis Experience Web-Based Instructional Technologies, Gary Eugene Deroest Jan 2019

How People With Multiple Sclerosis Experience Web-Based Instructional Technologies, Gary Eugene Deroest

Walden Dissertations and Doctoral Studies

People with the autoimmune disease multiple sclerosis (MS) have few options for

educational activities. Although web-based instruction may be a viable option, little is known about how people with MS perceive this form of learning. The purpose of this qualitative study was to understand the experiences of people with MS regarding web- based instruction. The 3 learning structures--differentiated instruction, collaborative learning, and assistive technology--provided the conceptual framework for this research. Nine volunteers from the Pacific Northwest area of the United States who have MS were individually interviewed for this basic qualitative study. Transcripts were analyzed using open, axial, and selective …