Digital Commons Network^™

Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied By Immunogenic Cell Death In Murine Models Of Lymphoma And Colorectal Cancer, Alessandra Rossi, Olga N. Pakhomova, Peter A. Mollica, Maura Casciola, Uma Mangalanathan, Andrei G. Pakhomov, Claudia Muratori

Bioelectrics Publications

Depending on the initiating stimulus, cancer cell death can be immunogenic or non-immunogenic. Inducers of immunogenic cell death (ICD) rely on endoplasmic reticulum (ER) stress for the trafficking of danger signals such as calreticulin (CRT) and ATP. We found that nanosecond pulsed electric fields (nsPEF), an emerging new modality for tumor ablation, cause the activation of the ER-resident stress sensor PERK in both CT-26 colon carcinoma and EL-4 lymphoma cells. PERK activation correlates with sustained CRT exposure on the cell plasma membrane and apoptosis induction in both nsPEF-treated cell lines. Our results show that, in CT-26 cells, the activity of …

Land Acknowledgment, Scripting And Julius Caesar, Jeffery G. Hewitt

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

This essay follows my presentation at Osgoode’s 21st Constitutional Cases Conference on the growing practice of land acknowledgments, honour and the legacy of now retired Chief Justice McLachlin. During the presentation, I examined some of the Supreme Court of Canada’s constitutional cases arising out of section 35 of the Constitution Act, 1982, along with the practice of land acknowledgments in academic spaces. What follows is an essay critically examining scripted land acknowledgments mainly from post-secondary institutions in Canada. Are land acknowledgments contributing to Canada’s national reconciliation project as so often purported? I consider whether the practice is becoming too comfortable …

One Hundred Years Of The Art And Architecture Of The Laie Temple

Mormon Pacific Historical Society

PowerPoint slide notes from a presentation by Sharon R. Gray, November 16, 2019, for the Mormon Pacific Historical Society (MPHS) Conference celebrating the Centennial of the Dedication of the Laie Hawai’i Temple.

Slide 1. Title Page 100 Years of the Art and Architecture of the Laie Hawai’i Temple. Image of the Laie Temple watercolor drawing by Paul L. Anderson.

A Tesol Ma Introductory Course: A Course For New Tesol Ma Students At Brigham Young University, Paula Celina Cabrera Campos

TESOL MA Projects

Concerns at the beginning of a graduate program may or may not be met promptly enough to ensure students will all begin confidently. Not all graduate students understand what is expected of them at the beginning of their programs and where they can go to receive the necessary help. The Introductory TESOL MA Course has been designed to bridge this gap and support students in their desire to feel more prepared for this academic challenge. The three-module online course addresses the most common topics graduate students wish they had known at the beginning of their graduate experience. The course will …

Trajectories In The Evolution Of Mormon Studies On Faith And Science, Steven L. Peck

Mormon Studies Review

The relationship between science and the Church of Jesus Christ of Latter-day Saints has been and continues to be a complicated story. Concerns and differing perspectives about science provided the underlying context for a number of formal and informal institutional directions taken by the church in the late nineteenth- and early twentieth-centuries. Often, these were influenced by differences in opinion about science among various leaders of the church. Areas in which science played a role include: the relationship between secular and church education, a battleground in framing doctrinal questions about creation—including syncretic influence from the rise of Christian fundamentalism and …

Gail Enough, Gail Roberts

Inscape

According to the U.S. Social Security database, the name ''.Abigail" as a female first name has been in the top 1000 names used every single year since 1901. It's been consistently in the top 10 and top 20 since 1998. In fact, 0.8% of female babies born in 2005 were named

Abigail.

Doing Business In The World Without Becoming Worldly, Lindon J. Robison, David R. Just, Jeffery R. Oliver

BYU Studies

Doing business in the world consists of, among other things, exchanging goods and services. One way people reflect who they are and what they love most is by what they exchange and by the quantities and terms with which they exchange goods and services.

Eroticism As A Metaphor For The Human-Divine Relationhip In Attar’S Conference Of The Birds, Or Mantiqu’T-Tair, Marisa Sikes

Quidditas

Farídu’d-Dín Ἁṭṭār’s The Speech of the Birds employs transgressive erotic imagery in multiple sub-tales in ways that both enhance the frame tale’s significance and suggest that persistent, discrete categories of love poetry and religious poetry are untenable as far as Ἁṭṭār’s works are concerned. Eroticism in Ἁṭṭār’s work paradoxically elicits shock and supports orthodoxy, sometimes simultaneously. In the narrative of Shaikh-i Sam’ān religious taboos are broken by a Muslim shaikh devoted to a Christian beloved who spurns him continuously. In “The Princess and the Beautiful Slave-Boy” eroticism is overtly presented as a metaphor for temporary, ecstatic union with the divine. …

Chloroviruses Lure Hosts Through Long-Distance Chemical Signaling, David Dunigan, Maitham Ahmed Al-Sammak, Zeina Al-Ameeli, Irina Agarkova, John Delong, James L. Van Etten

James Van Etten Publications

Chloroviruses exist in aquatic systems around the planet where they infect certain eukaryotic green algae that are mutualistic endosymbionts in a variety of protists and metazoans. Natural chlorovirus populations are seasonally dynamic but the precise temporal changes in these populations and the mechanisms that underlie them have, heretofore, been unclear. We recently reported the novel concept that predator/prey-mediated virus activation regulates chlorovirus population dynamics, and in the current manuscript demonstrate virus packaged chemotactic modulation of prey behavior.

Viruses have not previously been reported to act as chemotactic/chemo-attractive agents. Rather, viruses as extracellular entities are generally viewed as non-metabolically active spore-like …

The Future Of Facial Recognition Is Not Fully Known: Developing Privacy And Security Regulatory Mechanisms For Facial Recognition In The Retail Sector, Elias Wright

Fordham Intellectual Property, Media and Entertainment Law Journal

In recent years, advances in facial recognition technology have resulted in a rapid expansion in the prevalence of private sector biometric technologies. Facial recognition, while providing new potentials for safety and security and personalized marketing by retailers implicates complicated questions about the nature of consumer privacy and surveillance where a “collection imperative” incentivize corporate actors to accumulate increasingly massive reservoirs of consumer data. However, the law has not yet fully developed to address the unique risks to consumers through the use of this technology. This Note examines existing regulatory mechanisms, finding that consumer sensitivities and the opaque nature of the …

Dirty Little Secrets: Fracking Fluids, Dubious Trade Secrets, Confidential Contamination, And The Public Health Information Vacuum, Elliot Fink

Fordham Intellectual Property, Media and Entertainment Law Journal

While the carbon energy industry has frequently claimed that hydraulic fracturing processes and ingredients are proprietary and protected by trade secret laws, their large scale and volume nationwide and the well-documented dangers that they pose to public health have brought fracking under scrutiny. When individuals have been adversely impacted in their own backyards, weak federal and state laws and regulation have generally left these impacted citizens with little to no recourse and part of this problem stems from questionable uses of privacy law, specifically dubious claims of trade secrecy. Focusing specifically on Pennsylvania as a model of insufficient state regulation …

Twisting Facts To Suit Theories: In Defense Of Sherlock, Alicia Defonzo

English Faculty Publications

[First paragraph]

In August 2011, the Albemarle County school board unanimously voted to remove Sir Arthur Conan Doyle’s A Study in Scarlet from the sixth-grade curricula. Over twenty students beseeched the board for the book to remain, and they were ignored. Teachers were afraid to voice their opinions on the matter. The novel has not been taught since in Albemarle, on any grade level, nor any other Sherlock Holmes texts.

Effects Of Inbreeding On Life-History Traits And Sexual Competency In Decorated Crickets, Scott K. Sakaluk, Jeannine Oldzej, Christine J. Poppe, Jenny L. Harper, Ian G. Rines, Kylie J. Hampton, Kristin R. Duffield, John Hunt, Ben M. Sadd

Faculty Publications – Biological Sciences

Although inbreeding depression in life-history traits has been well characterized, inbreeding effects on mating behaviour and sexually selected traits have been less well studied. Here, we assess levels of inbreeding depression in a number of fitness-related reproductive parameters of female decorated crickets, Gryllodes sigillatus. We predicted that due to direct negative effects of inbreeding and a potential trade-off between reproduction and current survival, as suggested by effects of inbreeding on immunity, inbred females would show significantly reduced reproductive output compared with outbred females. We also examined sex-specific effects of inbreeding on mating competency, focusing specifically on the female's decision …

Burn It Down: The Incommensurability Of The University And Decolonization, Edwin Mayorga, L. Leidecker, D. Orr De Gutierrez

Educational Studies Faculty Works

As students and a professor in, but not of, an American liberal arts college, we ask whether our current institutions of higher education are compatible with a project of decolonization. Grounded in our own testimonios and drawing on a genealogy of Western knowledge, we argue that U.S. higher education authorizes and perpetrates settler colonial violence. Furthermore, based on our experiences surviving this violence, we conclude that the Universitas adapts to inhibit and neutralize institutional reform that might challenge its coloniality. As such, we find that higher education is not only incompatible, but irredeemably incommensurable with decolonization. In being incommensurable, we …

Town Of Plainfield, New Hampshire Annual Reports 2018. Annual Reports Of The Officers And Selectmen And The School District., Plainfield Town Representatives

Plainfield, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

2019 Warbler, Eastern Illinois University

The Warbler

The 2019 Warbler, yearbook of Eastern Illinois University.

A Rational Approach To Sentencing Offenders For Animal Cruelty: A Normative And Scientific Analysis Underpinning Proportionate Penalties For Animal Cruelty Offenders, Mirko Bagaric, Jane Kotzmann, Gabrielle Wolf

South Carolina Law Review

No abstract provided.

Applying Old Rules To New Tools: Employment Discrimination Law In The Age Of Algorithms, Matthew U. Scherer, Allan G. King, Marko J. Mrkonich

South Carolina Law Review

No abstract provided.

Kentucky Water Resources Research Institute, University Of Kentucky: Annual Technical Report 2018, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

In 2018, KWRRI launched a new website, https://www.research.uky.edu/kentucky-water-resources-research-institute, to better meet the needs of its stakeholders. KWRRI also established a repository for KWRRI’s reports, https://uknowledge.uky.edu/kwrri/. The repository includes historical KWRRI reports, annual symposium proceedings, technical reports, and the Water Distribution System Research Database. During the reporting period, KWRRI produced two editions of its semi-annual newsletter (Spring 2018 and Winter 2019). The newsletter provides updates, facilitates information sharing, and increases communication among those in the Kentucky water community. The 2019 Kentucky Water Resources Annual Symposium was held on March 25, 2019, in Lexington, Kentucky. The day-long symposium, attended by …

Metabolism Reprogramming In Hexavalent Chromium-Induced Human Lung Carcinogenesis, James Tate Fortin Wise

Theses and Dissertations--Pharmacology and Nutritional Sciences

Hexavalent chromium, Cr(VI), is an established human carcinogen that is a worldwide environmental health concern. It is well understood that reactive oxygen species, genomic instability, and DNA damage repair deficiency are important contributors to Cr(VI)-induced carcinogenesis. After decades of research some cancer hallmarks remain understudied for the mechanism of Cr(VI) carcinogenesis. Dysregulated cellular energetics have been established as a hallmark of cancer. Energy pathways that become dysregulated in cancer include mitochondrial respiration, lipogenesis, pentose phosphate pathway, one carbon metabolism, and increased anaerobic glycolysis in the presence of oxygen or ‘Warburg effect’.

To investigate metabolism changes in Cr(VI) carcinogenesis, we exposed …

The Absolute Insurer Rule: An Unconstitutional And Ineffective Means Of Mitigating Illegal Equine Drugging In The “Sport Of Kings”, Brian Calhoun Mundell

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Lasix Is A "Failed Experiment": Why The United States Should Follow Other Countries And Ban Lasix, Caitlyn Barnes

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

A Look At How United States Immigration And Labor Policy Affect The Foreign Workforce On American Farms, Benjamin A. Dennison

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Exploring Legal And Policy Responses To Opioids: America's Worst Public Health Emergency, James G. Hodge Jr., Chelsea Gulinson, Leila F. S. Barraza, Walter G. Johnson, Drew Hensley, Haley R. Augur

South Carolina Law Review

No abstract provided.

Choosing A Baby Formula, Healthychildren.Org

Infant 0-1 Year

No abstract provided.

Bait Guidelines For Commercial Fisheries In Western Australia, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Occasional Publications

No abstract provided.

The Compensation For Victims Of Disasters In Belgium, France, Germany, And The Netherlands, Véronique Bruggeman, Michael Faure

Loyola Consumer Law Review

No abstract provided.

Antitrust Analysis Of Nopec Legislation, Harry First, Darren Bush

Loyola Consumer Law Review

This Article analyzes the proposed "No Oil Producing and Exporting Cartels Act of 2019" (NOPEC). This legislation, which was introduced in the United States Senate and House of Representatives, addresses the antitrust issues involved in suing the Organization of the Petroleum Exporting Countries (OPEC), their member states and their state owned oil companies (SOEs), other states and their SOEs, and private companies for their participation in an international cartel that has long been involved in regulating the production and distribution of oil and other petroleum products. It is our view that this proposed legislation provides a relatively moderate approach to …

Town Of Dunbarton, New Hampshire For The Fiscal Year Ending December 31, 2018., Dunbarton Town Representatives

Dunbarton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report For The Town Of Hollis, New Hampshire For The Year Two Thousand Eighteen. Annual Reports Of The Officers And Committees Of The Town Of Hollis, New Hampshire For The Year Ending December 31, 2018 With Reports Of The Hollis School District And The Hollis/Brookline Cooperative School District., Hollis Town Representatives

Hollis, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.