Digital Commons Network^™

Isolated Nucleus Stiffens In Response To Low Intensity Vibration, Joshua Newberg

Boise State University Theses and Dissertations

The nucleus, central to all cellular activity, relies on both direct mechanical input and its molecular transducers to sense and respond to external mechanical stimuli. This response occurs by regulating intra-nuclear organization that ultimately determines gene expression to control cell function and fate. It has long been known that signals propagate from an extracellular environment to the cytoskeleton and into nucleus (outside-in signaling) to regulate cell behavior. Emerging evidence, however, shows that both the cytoskeleton and the nucleus have inherent abilities to sense and adapt to mechanical force, independent of each other. While it has been shown that isolated nuclei …

Acute Exposure To Tcdd Increases Liver Disease Progression In Mice With Carbon Tetrachloride-Induced Liver Injury, Giovan N. Cholico

Boise State University Theses and Dissertations

Liver disease is a worldwide problem and the 9^th leading cause of death in the United States. Common causes of liver disease include alcohol abuse, virus infection, and nonalcoholic fatty liver. Regardless of etiology, liver damage elicits inflammation and drives the activation of hepatic stellate cells (HSCs), which deposit collagen throughout the liver. During chronic injury, excessive collagen deposition, referred to as fibrosis or “scarring”, can progress to cirrhosis, cancer, and organ failure. Emerging evidence indicates a strong association between liver disease and exposure to environmental chemicals. This research investigated mechanisms by which exposure to the environmental contaminant 2,3,7,8-tetrachlorodibenzo- …

Phosphorus Runoff Risk Assessment In Karstic Regions Of The United States, Andrew N. Sharpley, Phillip D. Hays, Karl W. Vandevender, Mike B. Daniels

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

The Phosphorus (P) Index risk assessment tool has been widely adopted across the United States to identify and rank site vulnerability to P runoff as part of the Natural Resources Conservation Service nutrient management planning (NMP) process. However, limited success has been achieved in addressing the risk of P loss by subsurface flow pathways, despite its relative importance in certain areas of the United States, particularly in those U.S. states dominated by karst terrain. Here we review how states with varying land areas classified as having karst features address the risk of P runoff during the NMP process. Indices adopted …

‘Overreaching’ Or ‘Overreacting’? Reflections On The Judicial Function And Approaches Of Wto Appellate Body, Weihuan Zhou, Henry S. Gao

Research Collection Yong Pung How School Of Law

Since 2017, the US has blocked appointments to the WTO Appellate Body (AB), citing various concerns over its judicial approach, with the most significant being the issue of judicial overreach. This article provides a critical analysis of this issue and makes important contributions to the ongoing debate. Drawing on the fundamental function of the WTO, it offers a fresh approach to assess judicial overreach and shows that AB rulings in major non-trade remedy cases (that have consistently concerned the US) have served that function and hence should not be treated as ‘overreaching’. We argue that, the allegation of judicial overreach, …

Design Optimization For A Compliant,Continuum-Joint, Quadruped Robot, Vallan Gray Sherrod

Theses and Dissertations

Legged robots have the potential to cover terrain not accessible to wheel-based robots and vehicles. This makes them better suited to perform tasks, such as search and rescue, in real-world unstructured environments. Pneumatically-actuated, compliant robots are also more suited than their rigid counterparts to work in real-world unstructured environments with humans where unintentional contact may occur. This thesis seeks to combine the benefits of these two type of robots by implementing design methods to aid in the design choice of a 16 degree of freedom (DoF) compliant, continuum-joint quadruped. This work focuses on the design optimization, especially the definition of …

Evaluation Of Multimodal Anesthetic Drugs Combination In Goats Undergoing Laparo-Ovariectomy, Elbialy Elmorsy, Khalid S. Abouelnasr, Esam Mosbah, Adel E. Zaghloul

Mansoura Veterinary Medical Journal

Objective: To evaluate the effect of multimodal analgesic drugs for alleviation of pain accompanying laparo-ovariectomy in goat. Design: Randomized controlled experimental study. Animals: Sixteen goats ageing 8-18 months and weighing 20 kg on average. Procedures: The proposed site of laparotomy in all animals was infiltrated with lidocaine hydrochloride 1% 15 minutes before surgery started. The goats were allocated into four groups of four animals each; first group (L): animals received Lidocaine infltration , second group (PL): animals received Piroxicam at a dose rate of 5 mg/kg IM, third group (PPL): animals received Piroxicam and Propofol at a dose rate of …

Life Skill Development And Financial Impact Associated With A Youth Livestock Sales Program, Holly Evans, Dean Jousan, Erdogan Memili, Leigh Beckman

Journal of Youth Development

he Sale of Junior Champions is a premier livestock auction and youth scholarship program held at Dixie Nationals as a part of Mississippi’s junior livestock program. The sale is open to 4-H and FFA members who qualified their livestock at the annual Dixie National Junior Round-Up. While youth livestock sales programs are commonly found at state and county fairs throughout the United States, demographic information and information concerning financial and life skill impacts of the program on participants is limited. Therefore, a survey instrument for the 2018 sale was designed to determine how the event has impacted the financial burden …

Does Equine Assisted Learning Create Emotionally Safe Learning Environments For At-Risk Youth?, Katie Cagle-Holtcamp, Molly Christine Nicodemus, Julie Parker, Mattie Helen Dunlap

Journal of Youth Development

Equine assisted learning (EAL) is a form of experiential learning that is quickly growing in interest within the educational community. A challenge with experiential learning programs for at-risk youth is creating an emotionally safe environment that opens up the participants to learning. Nevertheless, EAL has been credited with the development of life skills in youth that promote educational achievement, but research tracking the development of emotional safety and learning, specifically associated with programming dedicated to educating participants about the horse, is limited. Therefore, the objective of this study was to determine if EAL, with programming centered around equine education, will …

A Residential Camp’S Impact On Youths’ Leadership Skills And Natural Resource Knowledge, Shandra Nicole Frey, Vernon Parent

Journal of Youth Development

Learning transcends the classroom. To better understand the natural world around them, it is critical that youth have opportunities to make connections and apply their learning in real-world settings. Improving youths’ perceived skills and knowledge contributes to increased academic motivation and continued leadership development. Multi-day residential natural resource camps have shown the ability to teach ecological concepts and develop land management skills, critical thinking skills, and decision-making skills. We tested the ability of a remotely located residential camp to improve leadership skills and natural resource knowledge, using a pre- and post-camp self-assessment, combined with a pre- and post-camp knowledge test. …

Human-Animal-Environment Interactions As A Context For Child And Adolescent Growth, Erin Flynn, Alexandra Zoller, Megan Mueller, Kevin Morris

Journal of Youth Development

Human-animal-environment interaction (HAEI) is increasingly used in special education. While most research of HAEIs has identified effects that broadly support positive special education outcomes, further research of HAEI-based interventions in these environments is needed. Semi-structured interviews were conducted with 18 teaching staff at a special education school that utilizes a range of HAEIs. The teachers are responsible for implementing evidence-based interventions to facilitate social-emotional learning (SEL), so assessing their unique perspectives on the impacts of HAEIs on student SEL outcomes is imperative. Phenomenological coding of the interviews identified 9 major themes that represented positive impacts as well as barriers and …

Effects Of Resampled Data On Time Series Forecasting Accuracy, Jennifer Garland

Theses and Dissertations

This thesis will look at time series forecasting of the air pollutants in Beijing, China and the power consumption of an individual household located in Sceaux, France. The forecast will be taken from two classical methods, the Holt-Winters’ methods and the Seasonal Autoregressive Integrated Moving Average (SARIMA) method. The Holt-Winters’ method will be looked at from the additive, multiplicative and damped methods. The SARIMA model will be looked at as a uni-variate model. In this thesis, it will be shown that less complex algorithms, such as the Holt-Winters’ methods can process larger data sets without the need of resampling, and …

Improving Grapheme-To-Phoneme Translation With The Use Of Nalu Attention Mechanisms, Brian Sheldon Smith

Theses and Dissertations

In recent years, Natural Language Processing in the field of machine learning has seen some major improvements. Data scientists have shown that neural networks are capable of breaking down semantics of sentences, translating languages, and answering complex questions with fast recall. While impressive, these feats all hinge on having access to a massive amount of clean text, or data sets with almost perfect grammar and spelling. Without this, neural networks will usually fail to converge on a meaningful result. To partially this dependency, Grapheme-to-Phoneme conversion can be employed. This is the conversion of words from their spellings to a form …

Parsing The Effects Of Demography, Climate, And Management On Recurrent Brucellosis Outbreaks In Elk, Gavin C. Cotterill, Paul C. Cross, Jerod A. Merkle, Jared D. Rogerson, Brandon M. Scurlock, Johan T. Du Toit

Wildland Resources Faculty Publications

Zoonotic pathogens can harm human health and wellbeing directly or by impacting livestock. Pathogens that spillover from wildlife can also impair conservation efforts if humans perceive wildlife as pests. Brucellosis, caused by the bacterium Brucella abortus, circulates in elk and bison herds of the Greater Yellowstone Ecosystem and poses a risk to cattle and humans. Our goal was to understand the relative effects of climatic drivers, host demography, and management control programs on disease dynamics.

Using > 20 years of serologic, demographic, and environmental data on brucellosis in elk, we built stochastic compartmental models to assess the influences of climate forcing, …

An Evaluation Of The Utility Of The Performance Diagnostic Checklist - Human Services (Pdc-Hs): A Comparison Of Formal And Informal Assessment Strategies, Cherish Chalk

Theses and Dissertations

The PDC-HS is a performance assessment tool that assists in the identification of variables contributing to performance problems among human service employees. The purpose of this study was to evaluate the utility of the PDC-HS as a formal assessment strategy. Specifically, the PDC-HS was compared to an informal assessment strategy consisting of a single open-ended interview question and a single structured interview question. Participants included 40 supervisors in varying positions in the human services industry. Descriptive statistics were used to compare participant responses to the open-ended and structured questions to the results indicated by the PDC-HS. Results suggest that the …

Life Skill Development And Financial Impact Associated With A Youth Livestock Sales Program, Holly Evans, Dean Jousan, Erdogan Memili, Leigh Beckman

Journal of Youth Development

he Sale of Junior Champions is a premier livestock auction and youth scholarship program held at Dixie Nationals as a part of Mississippi’s junior livestock program. The sale is open to 4-H and FFA members who qualified their livestock at the annual Dixie National Junior Round-Up. While youth livestock sales programs are commonly found at state and county fairs throughout the United States, demographic information and information concerning financial and life skill impacts of the program on participants is limited. Therefore, a survey instrument for the 2018 sale was designed to determine how the event has impacted the financial burden …

Effects Of Mercury On The Dopamine Transporter Cell Surface Expression In Pc12 Cells, Christina Hui

Student Theses

Environmental factors, such as heavy metal exposures, have been suggested to have an impact not only on neurodegenerative disease, such as Parkinson’s disease, but also on psychostimulants abuse and their toxicity. In this study, two questions were addressed: 1) effects of mercuric chloride on parkinsonian toxicant 1-methyl-4-phenylpyridinium (MPP⁺) induced cytotoxicity and 2) effects of mercuric chloride on cell surface dopamine transporter. Pheochromocytorma cells (PC12) were treated with various concentrations of mercuric chloride (0.02~2.0 ppm) for 4 hours with and without 0.1 mM MPP⁺. Significant potentiation of toxicity was observed when there was co-treatment with 0.5 ppm …

Cattle Industry Funding Scheme Annual Report 2018/2019, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

In June 2010 the Cattle Industry Funding Scheme (IFS) was introduced to address biosecurity threats relevant to the Western Australian (WA) cattle industry. The Scheme was established under the Biosecurity and Agriculture Management Act 2007 to enable cattle producers to identify the pest and disease priorities at a whole-of-industry level and to raise funds for activities to address these priorities.

There are currently three Industry Funding Schemes in operation. In addition to the Cattle IFS, there is a Sheep and Goat IFS and a Grains, Seeds and Hay IFS. The three IFSs operate in a similar manner.

The purpose of …

Implementation Of Provider Education For A Subanesthetic Ketamine Infusion For Acute Analgesia In Opioid Tolerant Postpartum Patients, Leah Baecht

Doctor of Nursing Practice Projects

The current opioid epidemic demands the development of new management policies and staff education to increase awareness of issues and improve care of patients with Opioid Use Disorder (OUD). A recent dramatic increase in OUD during pregnancy has paralleled the epidemic observed in the general population. The combination of OUD and cesarean delivery, place both the mother with OUD and neonate at risk for increased postoperative complications. The purpose of this project was to evaluate and increase staff knowledge regarding OUD in obstetrics. An analysis of staff knowledge was performed via surveys both pre and post dissemination of evidence. The …

Platelet-Rich Plasma Can Release Nutrient Factors To Promote Facial Nerve Crush Injury Recovery In Rats, Liheng Li, Jing Cai, Yang Yuan, Yanyan Mao, Lei Xu, Yuechen Han, Jianfeng Li, Haibo Wang

Saudi Medical Journal

Objectives: To evaluate the effects of platelet-rich plasma (PRP) on promoting neural repair after facial nerve compression in rats and the mechanism by which this occurs. Methods: Adult Wistar rats (n=100) were divided into 3 groups: healthy controls, surgery-only, and surgery+PRP groups. The rats underwent nerve crush injury to establish a facial palsy model. The blood from the rats was used to prepare the PRP for application to the injury site. The evaluation methods included vibrissae movement, eyelid closure, and electrophysiology. Electron microscopy, immunohistochemistry, and real-time polymerase chain reaction (PCR) were used to detect nutrient factor expression in the brain …

Traumatic Experiences Through The Queer Lens, Holden Guckenberg

Capstone Projects and Master's Theses

This is a collection of short stories based off of real trauma that LGBTQ+ individuals have experienced. I have interviewed seven people who identify within the LGBTQ+ community and listened to their traumatic stories. Based on their stories, I have written their accounts with trauma while expanding and taking creative freedom to better enunciate and bring-forth their stories. Trauma affects the LGBTQ+ community at a greater height than it does the general population. It’s important to recognize this fact so that we can support those people who have faced tremendous adversity in the form of trauma. In one form or …

Gnome Waste Warriors: Waste Reduction Through Sustainability, Hayley E.R. Frost Rubino

Capstone Projects and Master's Theses

The focus of this Capstone Project was on how waste and waste reduction could positively impact a community. Waste reduction is an important issue because the negative impacts of waste affect the whole planet. By educating Monterey Gnome School (MGS) about waste, changes in daily habits are intended to result in lasting change. An evidence-based argument is offered that waste is a global issue that negatively impacts the earth's landmasses, oceans, and human health. Both MGS staff and students were interviewed and surveyed, as their perspectives provide unique aspects of thinking about waste issues. The themes that emerged from an …

#Queer: Community, Communication, And Identity In The Digital Age, Margaret Allen-Young

Capstone Projects and Master's Theses

The creation and facilitation of community among LGBTQ+ people has always been necessary as a means of support, protection, and affirmation in a discriminatory society. The common perception of this community imagines the migration of people from rural areas to urban meccas like San Francisco and New York in search of likeminded people. However, the advent of new technology has allowed for community building and organizing to occur more easily without face-to-face contact. In this paper I utilize existing literature, including a large study on queer rural populations, and real-world examples such as the platform Tumblr to explore the evolution …

Digital Simulations For Grade 7 To 10 Mathematics, Ma. Louise Antonette N. De Las Peñas, Debbie Marie Verzosa, Maria Alva Q. Aberin, Len Patrick Dominic M. Garces, Flordeliza F. Francisco, Evangeline P. Bautista, Mark Anthony C. Tolentino, Winfer C. Tabares

Mathematics Faculty Publications

This article describes a Department of Science and Technology – Philippine Council for Industry, Energy and Emerging Technology (DOST-PCIEERD) project aimed to facilitate the implementation of the mathematical objectives raised by the Department of Education’s (DepEd) K to 12 program in the Philippines through the use of innovative digital technologies. In particular, a selection of application software (“apps”) were created for Grade 7 to 10 mathematics that covered topics indicated in the five strands outlined in the K to 12 program – namely (1) number, (2) geometry, (3) measurement, (4) patterns and algebra, and (5) statistics and probability. The design …

Changes In Avian Diversity And Potential Invasive Seed Dispersal Post-Wildfire In A Southeastern Deciduous Forest; Flipper Bend Woods, Signal Mountain, Tennessee, Mary Elizabeth Feely

Masters Theses and Doctoral Dissertations

In eastern deciduous forests, fire-disturbance and its ecological implications have not been heavily studied. In Tennessee, a recently burned site (2016) presented a unique opportunity to analyze habitat regrowth two-three years after a major wildfire thought to have been worsened by invasive plants. In order to examine post-fire recovery and invasive plant recolonization, researchers observed the diversity of avian species in a burned and unburned site. Using mist-nets, line-transects, and vegetation analysis, this study found that though the unburned site was higher in avian diversity, the burned site appeared to be suitable habitat for multiple disturbance-dependent avian species. There was …

The Grand Narrative Worldview: A Narrative Inquiry Into The Impact Of Biblical Metanarrative Teaching In Liberty University’S School Of Divinity Global Studies Program, Chesed Anne Dent

Masters Theses

There is limited research and literature on the effectiveness of narrative-centered academic learning environments that utilize biblical metanarrative as a tool for teaching. Literature exists showing that story is an effective tool within education, within discipleship, and within training for cross-cultural effectiveness. This narrative inquiry research study focused on Liberty University’s Global Studies Program, a program that overlaps these distinct areas into one platform. Global Studies uses the power of story through the Grand Narrative of Scripture to teach students academic content, equip them as messengers of God’s Story, and help them assess and understand their own narratives within a …

Developing A Theoretical Framework For Visualization-Based Pedagogical Content Knowledge (V-Pck) Based On Middle School Teachers’ Views And Uses Of Visualizations As An Instructional Tool, Jacqueline Samuel

Dissertations

Visualizations is a categorical term that is often used to provide visual imagery to the communication of processes, concepts, exemplar phenomena, and general information. Objects such as graphs, tables, diagrams, animations, and pictures fall in this category. Existing literature focuses primarily on the use of visualizations in the science field at the high school level, collegiate levels, and in pre-service teacher education programs. A gap in the literature exists which examines how science teachers at the middle school level perceive and use visualizations as instructional components in the classroom. The purpose of this study was to examine science teachers views …

Characterization Of Plasmids Harbored By Vibrio Cholerae Isolates Endemic To The Rio Grande Delta, Viviana Trevino

Theses and Dissertations

Cholera is a diarrheal disease responsible for considerable morbidity and mortality globally. Epidemics along the Rio Grande Delta were reported during the 1850s, and the etiological agent Vibrio cholerae, remains endemic, thus presenting a unique opportunity for a study of historical and biological relevance. V. cholerae strains were isolated from two locations: the Rio Grande River under a bridge linking Brownsville to Matamoros (site 21) and where the river empties into the Gulf of Mexico (site 42). Two strains from site 21, and one from site 42 were selected to isolate, subclone, sequence, assemble and annotate extra-chromosomal elements. Results …

Synthesis And Study Of Hydroxytyrosol Derivatives, Ebenezer Ametsetor

Electronic Theses and Dissertations

Hydroxytyrosol is one of the most powerful known antioxidants. It is a naturally occurring polyphenol, most commonly produced in olive trees, (Olea europaea). The remarkable antioxidant and pharmacological properties of hydroxytyrosol has made it an outstanding compound in the polyphenol family and of great interest to many researchers. Hydroxytyrosol can scavenge free radicals produced during cellular oxidative stress and helps to protect the integrity of cells in living systems. Despite its numerous biological and pharmacological uses, it is found in very low concentration in olive oil, this limits its availability for biomedical applications. This work reports a novel and effective …

Role Of Topoisomerase Ii Alpha In Dna Topology And T Cell Responses During Chronic Viral Infections, Stella Chinyere Ogbu

Electronic Theses and Dissertations

The clearance of viruses is largely dependent upon the activation of T cells to generate a robust immune response. However, host responses are suppressed during chronic viral infections. In this thesis, we explored the role of Top2α in DNA topology in individuals with chronic HBV, HCV, and HIV infections. We found that Top2α protein expression and activity were low in T cells derived from chronically virus-infected individuals compared to healthy subjects. Using CD4⁺ T cells treated with Top2α inhibitor or poisoner as a model, we demonstrated that Top2α inhibition disrupts the DNA topology, suppresses DNA repair kinase (ATM), and …

Age And Seasonal Change In The Chronobiology Of A Spider With An Exceptionally Long-Period Circadian Clock, Shae Crain

Electronic Theses and Dissertations

This study examines locomotor activity in samples of Frontinella pyramitela collected over its active season (April-October) to investigate whether seasonality and/or age may help explain the exceptional variability typically found in spider clock systems. Despite its noteworthy variability (%CV= 7.7), we have found that Frontinella has a mean free-running period of 28.4±2.18 hours that does not significantly vary over time. There is no correlation between day length and free-running period, indicating that varying length of FRP is not a function of photoperiod length. In LD 12:12 h, the window of activity is significantly smaller in April, gradually widening as the …