Digital Commons Network^™

International Consensus On Quality Standards For Multiple Sclerosis Care: Results From A Modified Delphi Process, J Hobart, A Bowen, L Eberhard, G Pepper, G Giovannoni

Peninsula Medical School

Background and aims: The importance of prompt intervention in multiple sclerosis (MS) was described in the widely endorsed report, Brain health: time matters in multiple sclerosis.1 The present study aimed to define standards for the timing of key steps in the care pathway. Methods: An international group of 29 MS neurologists was recruited to participate in a Delphi process. Across five rounds, they defined ‘core’, ‘achievable’ and ‘aspirational’ standards (to reflect a minimum, good and high standard of MS care, respectively). A Reviewing Group of 31 MS nurses, experts with MS and allied healthcare professionals reviewed the results and provided …

Repositioning Of Omarigliptin As A Once-Weekly Intranasal Anti-Parkinsonian Agent, Bassam M. Ayoub, Shereen Mowaka, Marwa M. Safar, Nermeen Ashoush, Mona Arafa, Haidy E. Michel, Mariam M. Tadros, Mohamed M. Elmazar, Shaker A. Mousa

Pharmacy

© 2018 The Author(s). Drug repositioning is a revolution breakthrough of drug discovery that presents outstanding privilege with already safer agents by scanning the existing candidates as therapeutic switching or repurposing for marketed drugs. Sitagliptin, vildagliptin, saxagliptin & linagliptin showed antioxidant and neurorestorative effects in previous studies linked to DPP-4 inhibition. Literature showed that gliptins did not cross the blood brain barrier (BBB) while omarigliptin was the first gliptin that crossed it successfully in the present work. LC-MS/MS determination of once-weekly anti-diabetic DPP-4 inhibitors; omarigliptin & trelagliptin in plasma and brain tissue was employed after 2 h of oral administration …

Church Governance In Times Of Conflict, Denis Fortin Ed.

Faculty Publications

No abstract provided.

Why We Need An Educated Pastorate, Jiri Moskala

Faculty Publications

No abstract provided.

Asor 2017 Annual Meeting, Paul J. Ray

Faculty Publications

No abstract provided.

Uplifting The Non-Custodial Parent, Alina M. Baltazar

Faculty Publications

No abstract provided.

Christian Community: A Vital Ingredient For A Healthy Sabbath School, S. Joseph Kidder

Faculty Publications

No abstract provided.

Effective And Ineffective Pastors: A Study In Contrasts, H. Peter Swanson

Faculty Publications

No abstract provided.

Teachers' Perceptions Of Inclusion In A Pilot Inclusive Education Program: Implications For Instructional Leadership, Zachary Y. Mngo, Agnes Y. Mngo

Faculty Publications

© 2018 Zachary Y. Mngo and Agnes Y. Mngo. The opinions of general education secondary school teachers in seven select schools involved in a pilot inclusive education program in the Northwest Region of Cameroon were sought. The findings reveal that most teachers in Cameroon still prefer separate special education institutions to inclusive ones. These conclusions contradict earlier research which showed that resistance to integrated classrooms was emanating from beliefs and customs. Teachers with some training on teaching students with disabilities and more experienced and highly educated teachers were more supportive of inclusive education indicating that resistance to the practice is …

Finding God At Work In Our Family Roots, Keith Clouten

Faculty Publications

Follows the story of the Clouten family beginning in 1790 in England, then to Australia, then to Canada, and back to Australia.

The Norwegian Ancestry Of Oscar Martin Remington; Tracing His Roots In Roldal Parish, Hordaland County And Suldal Parish, Rogaland County, Norway And Telling The Story Of His Family In Juneau County, Wisconsin, Lawrence W. Onsager

Faculty Publications

Cataloging Data

Onsager, Lawrence William, 1944-

The Norwegian Ancestry of Oscar Martin Remington; Tracing His Roots in Roldal Parish, Hordaland County and Suldal Parish, Rogaland County, Norway and Telling the Story of His Family in Juneau County, Wisconsin. Mauston, Wisconsin and Berrien Springs, Michigan: The Lemonweir Valley Press, 2018.

1. Juneau County, Wisconsin

2. Norwegian-Americans--Wisconsin

3. Clifton Township, Monroe County, Wisconsin

4. Suldal Norwegian-American Settlement

5. Suldal Parish, Rogaland County, Norway

6. Roldal Parish, Hordaland County, Norway

7. Knutson Family

8. Remington Family

Preliminary Report On The 2016 Season Of The Madaba Plains Project: Tall Jalul Excavations 2016, Paul Ray, Paul A. Gregor, Robert D. Bates, Constance E. Gane, Randall Younker

Faculty Publications

No abstract provided.

Different Approaches And Limitations For Testing Phytoplankton Viability In Natural Assemblies And Treated Ballast Water, Maria Cecilia T.De Castro, Marcel J.W. Veldhuis, Timothy W. Fileman, Jason M. Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.

Using Natural Analogues To Investigate The Effects Of Climate Change And Ocean Acidification On Northern Ecosystems, Samuel S.P. Rastrick, Helen Graham, Kumiko Azetsu-Scott, Piero Calosi, Melissa Chierici, Agneta Fransson, Haakon Hop, Jason Hall-Spencer, Marco Milazzo, Peter Thor, Tina Kutti

School of Biological and Marine Sciences

No abstract provided.

Mobilisation Kinetics Of Hazardous Elements In Marine Plastics Subject To An Avian Physiologically-Based Extraction Test., Andrew Turner

School of Geography, Earth and Environmental Sciences

Samples of plastic collected from two beaches in southwest England (n = 185) have been analysed by XRF spectrometry for elements that are hazardous or restricted in synthetic polymers (namely, As, Ba, Br, Cd, Cr, Hg, Pb, Sb and Se). Overall, one or more restricted element was detected in 151 samples, with 15 cases exhibiting non-compliance with respect to the Restriction of Hazardous Substances (RoHS) Directive. Twelve plastics that were RoHS-non-compliant were subsequently processed into microplastic-sized fragments and subjected to an avian physiologically-based extraction test (PBET) that simulates the chemical conditions in the gizzard-proventriculus of the northern fulmar. Kinetic profiles …

Biogeography And Genetic Diversity Of The Atlantid Heteropods., Deborah Wall-Palmer, Alice K. Burridge, Erica Goetze, Frank R. Stokvis, Arie W. Janssen, Lisette Mekkes, María Moreno-Alcántara, Nina Bednaršek, Tom Schiøtte, Sørensen M Vinther, Christopher W. Smart, Peijnenburg K T.C.A.

School of Geography, Earth and Environmental Sciences

No abstract provided.

Mixtures Of Tritiated Water, Zinc And Dissolved Organic Carbon: Assessing Interactive Bioaccumulation And Genotoxic Effects In Marine Mussels, Mytilus Galloprovincialis, Holly B.C. Pearson, Lorna J. Dallas, Sean D.W. Comber, Charlotte B. Braungardt, Paul J. Worsfold, Awadhesh N. Jha

School of Geography, Earth and Environmental Sciences

No abstract provided.

I: Introduction., Caroline Floccia, Thomas D. Sambrook, Luche C Delle, Rosa Kwok, Jeremy Goslin, Laurence White, Allegra Cattani, Emily Sullivan, Kirsten Abbot-Smith, Andrea Krott, Debbie Mills, Caroline Rowland, Judit Gervain, Kim Plunkett

School of Psychology

The majority of the world's children grow up learning two or more languages. The study of early bilingualism is central to current psycholinguistics, offering insights into issues such as transfer and interference in development. From an applied perspective, it poses a universal challenge to language assessment practices throughout childhood, as typically developing bilingual children usually underperform relative to monolingual norms when assessed in one language only. We measured vocabulary with Communicative Development Inventories for 372 24-month-old toddlers learning British English and one Additional Language out of a diverse set of 13 (Bengali, Cantonese, Dutch, French, German, Greek, Hindi-Urdu, Italian, Mandarin, …

Ii: Methods., Caroline Floccia, Thomas D. Sambrook, Luche C Delle, Rosa Kwok, Jeremy Goslin, Laurence White, Allegra Cattani, Emily Sullivan, Kirsten Abbot-Smith, Andrea Krott, Debbie Mills, Caroline Rowland, Judit Gervain, Kim Plunkett

School of Psychology

The methods described in this chapter cover the cohort data collection, which constituted the common data set for all three studies reported in this paper. A sample of 430 bilingual toddlers, learning British English and one of 13 target Additional Languages (N = 372), or any other Additional Language (N = 58), were identified over a 2-year period. To increase variation in both English/Additional Language pairs and in the situational factors outlined above (language exposure, mode of exposure and demographic factors), data was collected through trained research assistants recruited in the six universities involved in this project (Bangor, Birmingham, Kent, …

Iv: Results For Studies 2 And 3: The Ukbtat Model And Its Application To Nontarget Additional Language Learners., Caroline Floccia, Thomas D. Sambrook, Luche C Delle, Rosa Kwok, Jeremy Goslin, Laurence White, Allegra Cattani, Emily Sullivan, Kirsten Abbot-Smith, Andrea Krott, Debbie Mills, Caroline Rowland, Judit Gervain, Kim Plunkett

School of Psychology

The aim of Study 2 was to develop the UKBTAT (UK Bilingual Toddlers Assessment Tool), the first screening tool for assessing the vocabulary size of bilingual 2-year-olds, in this case learning British English and one of the 13 target Additional Language. The aim of Study 3 was to establish the reliability of UKBTAT for bilingual children learning British English and any other non-target Additional Language. Norms for bilingual vocabulary in English were obtained through regression equations in linear mixed models, using variables shown to be predictive of comprehension and production in the previous analyses (Chapter 3). Similarly, norms for the …

Investigation Of Flocculation Dynamics Under Changing Hydrodynamic Forcing On An Intertidal Mudflat, C Guo, Qing He, Prooijen Bc Van, L Guo, Andrew J. Manning, Sarah Bass

School of Biological and Marine Sciences

© 2017 In situ floc size and turbulent shear stress were measured together with suspended sediment concentration to investigate the floc properties under changing hydrodynamic forcing over the intertidal mudflat. A tripod system was established in the field for a period of approximately one month, including ~ 6 days of stormy conditions in the middle of the investigation period. Mean floc size exhibited strong temporal variations within a tidal cycle, and inverse relationship was found between mean floc size and shear stress. Suspended sediment concentration (SSC) can modulate the flocculation dynamics when shear stress decreases down to enhancing flocculation. Asymmetrical …

Baseline Screening For The Presence Of Antimicrobial Resistance In E. Coli Isolated From Kuwait's Marine Environment, Ha Al-Sarawi, Awadhesh N. Jha, Craig Baker-Austin, Ma Al-Sarawi, Brett P. Lyons

School of Biological and Marine Sciences

No abstract provided.

Plankton As Prevailing Conditions: A Surveillance Role For Plankton Indicators Within The Marine Strategy Framework Directive, Abigail Mcquatters-Gollop, David Johns, Simon Greenstreet, Jacob Bedford

School of Biological and Marine Sciences

The Marine Strategy Framework Directive (MSFD) uses an indicator-based approach for ecosystem assessment; indicators of the state of ecosystem components ('state indicators') are used to determine whether, or not, these ecosystem components are at ‘Good Environmental Status’ relative to prevailing oceanographic conditions. Here, it is illustrated that metrics of change in plankton communities frequently provide indications of changing prevailing oceanographic conditions. Plankton indicators can therefore provide useful diagnostic information when interpreting results and determining assessment outcomes for analyses of state indicators across the food web. They can also perform a strategic role in assessing these state indicators by influencing target …

Assessing The Impact Of Benzo[A]Pyrene With The In Vitro Fish Gut Model: An Integrated Approach For Eco-Genotoxicological Studies., Laura M. Langan, Silvia Arossa, Stewart F. Owen, Awadhesh N. Jha

School of Biological and Marine Sciences

In vitro models are emerging tools for reducing reliance on traditional toxicity tests, especially in areas where information is sparse. For studies of fish, this is especially important for extrahepatic organs, such as the intestine, which, until recently, have been largely overlooked in favour of the liver or gill. Considering the importance of dietary uptake of contaminants, the rainbow trout (Oncorhynchus mykiss) intestine-derived cell line RTgutGC was cultured, to test its suitability as a high-throughput in vitro model. Benzo[a]pyrene (B[a]P) is an important contaminant and a model polycyclic aromatic hydrocarbon (PAH). Over 48 h exposure, a range of endpoints and …

On Beam Models And Their Paraxial Approximation, W. J. Waters, B. King

School of Engineering, Computing and Mathematics

No abstract provided.

Application Of Field-Portable-Xrf For The Determination Of Trace Elements In Deciduous Leaves From A Mine-Impacted Region, Andrew Turner, Chor Chi Chan, Murray T. Brown

School of Geography, Earth and Environmental Sciences

No abstract provided.

Catchment Changes In Response To Tectonics And Climate: Using River Terraces And Dem Data In The Southern High Atlas Mountains (Morocco), Jr Zondervan, M Stokes, Sj Boulton, Ae Mather, Mw Telfer

School of Geography, Earth and Environmental Sciences

Tectonics and climate drive the generation and transport of sediment in mountain rivers as these evolve over time. On a glacial-interglacial scale, in particular catchment reorganisation and catchment incision dynamics control these processes, and affect fan deposition in sedimentary basins. The Atlas Mountains in Morocco exhibit ongoing catchment reorganisation and an abundance of river terraces recording glacial fluvial aggradation and interglacial-glacial incisional periods, opening up insight into the processes behind catchment evolution over geological timescales. Topography and river profiles across drainage divides are similar in a stable divide, and if they are unequal they indicate active catchment reorganisation. When reorganisation …

From Rural Citizenship To The Rural Citizen: Farming, Dementia And Networks Of Care, Claire Kelly, Richard Yarwood

School of Geography, Earth and Environmental Sciences

Citizenship is gaining increased attention in the social sciences but has been under-utilised in rural studies. In this paper we argue that greater attention should be paid to social aspects of citizenship in order to understand participation in daily life and society. In doing so, emphasis needs to be placed on the rural citizen and how he or she engages with different communities across different scales. To explore these ideas we draw upon a case study of farmers living with dementia in Devon, UK. We use concepts of citizenship to explore their rights to services, the effectiveness of active citizenship …

Role Of Mtor In Autophagic And Lysosomal Reactions To Environmental Stressors In Molluscs, Susanna Sforzini, Michael N. Moore, Caterina Oliveri, Anna Volta, Awadhesh Jha, Mohamed Banni, Aldo Viarengo

School of Biological and Marine Sciences

No abstract provided.

Scotolemon Doriae Pavesi, 1878, A Soil-Dwelling Harvestman New To Britain (Opiliones: Phalangodidae), David T. Bilton

School of Biological and Marine Sciences

No abstract provided.