Digital Commons Network^™

Role Of The Gut Microbiota As A Natural Adjuvant For Vaccine, Nicole Benn, Gerard F. Hoyne

Health Sciences Papers and Journal Articles

Vaccines have provided the most beneficial contribution to public health. Generating antigen specific antibody responses and long lasting memory are crucial for the protective immunity offered by vaccination. Unfortunately, not all individuals respond in the same manner to vaccine formulations. The microbiota is established during postnatal development and remains relatively stable for long periods. Our understanding that the microbiota can have beneficial effects on human health has led immunologists to investigate how these organisms may shape the innate and adaptive immune responses of the host. In this review we examine the impact of the microbiota on the host immune responses …

Intraoperative Detection Of Blood Vessels With An Imaging Needle During Neurosurgery In Humans, Hari Ramakonar, Bryden C. Quirk, Rodney W. Kirk, Jiawen Li, Angela Jacques, Christopher R.P Lind, Robert A. Mclaughlin

Health Sciences Papers and Journal Articles

Intracranial hemorrhage can be a devastating complication associated with needle biopsies of the brain. Hemorrhage can occur to vessels located adjacent to the biopsy needle as tissue is aspirated into the needle and removed. No intraoperative technology exists to reliably identify blood vessels that are at risk of damage. To address this problem, we developed an “imaging needle” that can visualize nearby blood vessels in real time. The imaging needle contains a miniaturized optical coherence tomography probe that allows differentiation of blood flow and tissue. In 11 patients, we were able to intraoperatively detect blood vessels (diameter, >500 μm) with …

Do Frailty And Comorbidity Indices Improve Risk Prediction Of 28-Day Ed Reattendance? Reanalysis Of An Ed Discharge Nomogram For Older People, Evert Gips, Katrina Spilsbury, Claus Boecker, Rebecca Ng, Glenn Arendts

Health Sciences Papers and Journal Articles

Background: In older people, quantification of risk of reattendance after emergency department (ED) discharge is important to provide adequate post ED discharge care in the community to appropriately targeted patients at risk.

Methods: We reanalysed data from a prospective observational study, previously used for derivation of a nomogram for stratifying people aged 65 and older at risk for ED reattendance. We investigated the potential effect of comorbidity load and frailty by adding the Charlson or Elixhauser comorbidity index and a ten-item frailty measure from our data to develop four new nomograms. Model I and model F built on the …

Movement Economy In Soccer: Current Data And Limitations, Filippo Dolci, Nicolas H. Hart, Andrew Kilding, Paola Chivers, Benjamin Piggott, Tania Spiteri

Health Sciences Papers and Journal Articles

Soccer is an intermittent team-sport, where performance is determined by a myriad of psychological, technical, tactical, and physical factors. Among the physical factors, endurance appears to play a key role into counteracting the fatigue-related reduction in running performance observed during soccer matches. One physiological determinant of endurance is movement economy, which represents the aerobic energy cost to exercise at a given submaximal velocity. While the role of movement economy has been extensively examined in endurance athletes, it has received little attention in soccer players, but may be an important factor, given the prolonged demands of match play. For this reason, …

"I Am Tired Of Having To Prove That My Husband Was Dead." Dealing With Practical Matters In Bereavement And The Impact On The Bereaved, Pippa Blackburn, Caroline Bulsara

Health Sciences Papers and Journal Articles

This paper reports on experiences of dealing with practical matters after death. Semi structured interviews with bereaved individuals were thematically analyzed. Within the theme of coping, dealing with practical matters was a significant stressor and was found to be extremely challenging, time consuming, and to negatively impact on mental and emotional well-being. This study adds new insights on the challenges experienced by the bereaved when attending to practical matters and may help to inform the design of bereavement support, inform standard operating procedures of businesses, and government bereavement leave legislation.

Joan Finke Collection Of The Little Theatre Of Savannah, Inc., Zach S. Henderson Library Special Collections

Finding Aids

This collection consists of the letters, notes, and production materials collected by Joan Finke, by way of C. Robert “Bob” Jones. These materials span 1968-1981 and largely concern the activities of The Little Theatre of Savannah, Inc. but also include groups such as The Island Players of St. Simons Island, The Masquers (Armstrong State College’s theater group), Savannah’s symphony, the Georgia Theater Conference and other local groups.

Find this collection in the University Libraries' catalog.

Comparison Of Neuroprotective Efficacy Of Poly-Arginine R18 And R18d (D-Enantiomer) Peptides Following Permanent Middle Cerebral Artery Occlusion In The Wistar Rat And In Vitro Toxicity Studies, Diego Melani, Megan C. Bakeberg, Jane L. Cross, Vince W. Clark, Ryan S. Anderton, David J. Blacker, Neville W. Knuckey, Bruno P. Meloni

Health Sciences Papers and Journal Articles

We have previously demonstrated that arginine-rich and poly-arginine peptides possess potent neuroprotective properties, with poly-arginine peptide R18 identified as being highly effective at reducing infarct volume following middle cerebral artery occlusion (MCAO) in the Sprague Dawley rat. Since peptides synthesised using D-isoform amino acids have greater stability than L-isoform peptides due to increased resistance to proteolytic degradation, they represent potentially more effective peptide therapeutics. Therefore we compared the neuroprotective efficacy of R18 and its D-enantiomer R18D following permanent MCAO in the Wistar rat. Furthermore, as increased peptide stability may also increase peptide toxicity, we examined the effects of R18 and …

Added Value Of Second Biopsy Target In Screen-Detected Widespread Suspicious Breast Calcifications, Nathalie M. Falkner, Dana A. Hince, Gareth Porter, Ben Dessauvagie, Sanjay Jeganathan, Max Bulsara, Glen Lo

Health Sciences Papers and Journal Articles

Introduction: There is controversy on the optimal work‐up of screen‐detected widespread breast calcifications: whether to biopsy a single target or multiple targets. This study evaluates agreement between multiple biopsy targets within the same screen‐detected widespread (≥25 mm) breast calcification to determine if the second biopsy adds value.

Methods: Retrospective observational study of women screened in a statewide general population risk breast cancer mammographic screening program from 2009 to 2016. Screening episodes recalled for widespread calcifications where further views indicated biopsy, and two or more separate target areas were sampled within the same lesion were included. Percentage agreement and Cohen's Kappa …

Is There A Link Between Vitamin B And Multiple Sclerosis?, Natalie Nemazannikova, Kathleen Mikkelsen, Lily Stojanovska, Gregory L. Blatch, Vasso Apostolopoulos

Health Sciences Papers and Journal Articles

Background: Damage to the myelin sheath (demyelination) is one of the main manifestations of multiple sclerosis (MS). Interestingly, both MS and vitamin B deficiencies result in severe myelin degeneration, leading to loss in neuronal signal transmission.

Objective: Deficiency in vitamin B complex vary, although common symptoms include fatigue, increased oxidative stress, inflammation and demyelination. In particular, vitamin B12 (cobalamin) has had increased attention for its role in the methylation process, involvement in myelination and remyelination, and reversal of MS symptoms.

Method: Here, we discuss the role of vitamin B complex (B1, B2, B3, B4, B5, B6, B7, B9, B12) in …

The Importance Of Automaticity Development In Mathematics, Austin T. Baker, Josh Cuevas

Georgia Educational Researcher

This study examined whether students were reaching automaticity with single digit multiplication facts. A fourteen question interview was used to collect data. The first three questions asked the student basic information about themselves and their current math teacher. The next seven questions were math facts. The math facts chosen for the interview were a range of difficulty, starting with a simple problem like 1 x 9 and increasing in difficulty to 6 x 9. The last four questions were open-ended with the intent of gaining insight into whether the students were using strategies to complete the problems or if they …

Bridging Pedagogy And Practice: From Coursework To Field Experiences In A Teacher Preparation Program, Judith M. Emerson Phd, Pier Junor Clarke Phd, Alesia M. Moldavan Med

Georgia Educational Researcher

In this study, two teacher educators, one special education faculty and one mathematics education faculty, examined ways to infuse educational theory into their practice to develop preservice teachers’ ability to meet the demands of the 21^st century classroom. The study took place at an urban university in the southeastern United States where the teacher education program prepares future educators for the most diverse classroom settings existing in U.S. public schools today. Results informed the teacher educators of relevant challenges preservice teachers experience with regard to instructional design that addresses the needs of diverse learners. The action research study took …

Alternative Seating And Students' Perceptions: Implications For The Learning Environment, Alicia Stapp

Georgia Educational Researcher

Expectations placed on educators to improve academic performance continue to increase across the United States. One reason for this rise in expectancy is the enactment of The Every Student Succeeds Act (ESSA) of 2015. Replacing the No Child Left Behind (NCLB) Act of 2002, the ESSA mandates that “all students are taught to high academic standards” (ESSA, 2015). Subsequently, educators constantly seek best practices that foster effective learning environments. A component of the learning environment oftentimes excluded from research is the physical structure of a classroom, such as the type of seating in a classroom. Research suggests that students who …

Using School Choice To Connect To Mathematics Learning In A Statistics And Probability Course For K-8 Pre-Service Teachers, Ha Nguyen, Heidi Eisenreich

Georgia Educational Researcher

This pilot qualitative study explored K-8 pre-service teachers (PSTs)’ learning experience in a Statistics and Probability course and their ability to make connections between mathematics and their everyday lives when given opportunities to investigate mathematics through a social issue. Data from student surveys, assessments, and written reflections will be reported, analyzed, and discussed. The researchers also describe approaches and reflect upon experiences for PSTs while studying school choice voucher programs.

Stem Certification In Georgia’S Schools: A Causal Comparative Study Using The Georgia Student Growth Model, David E. Proudfoot, Ed.D., Michael Green, Ph.D., Jan W. Otter, Ph.D., David L. Cook, Ed.D.

Georgia Educational Researcher

The increase in demand for college and career ready students has driven the need for education reform to ensure K–12 schools can support student learning across all content areas and grade levels. A STEM Certification process was established by the Georgia Department of Education as part of an effort to reform public school STEM education. Additionally, an international STEM Certification procedure developed by AdvancED has been implemented in several Georgia schools. As a significant component of STEM certification guidelines, problem based learning has been incorporated to stimulate student interest in science, facilitate self-regulation, and increase pedagogical and content knowledge. As …

Implementing An Lgbtq Training For Teen Pregnancy Prevention Facilitators, Christopher F. Drescher, Elizabeth Devon Eldridge, Elizabeth Wood, Alexis L. Rossi, Lara Stepleman

Georgia Educational Researcher

Teen pregnancy and sexually transmitted infections remain a major health concern and are linked to a number of poor outcomes. Lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) youth are particularly at risk for these issues. Although evidence-based teen pregnancy prevention (TPP) programs exist, they are not necessarily tailored to meet the needs of LGBTQ youth. This paper reports on the development and implementation of a LGBTQ training for TPP facilitators working for the Augusta Partnership for Children in Augusta, GA. The four-hour workshop covered a range of topics including terminology, identity, intersectionality, and risk/resilience factors through a combination of lecture, …

City Squares And Power In Medieval Cairo Manifestations Of Socio-Political Power In The City Squares Of Medieval Cairo, Muhammed Emad Al Din Feteha

Theses and Dissertations

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Analysis Of The Impact Of Changes In The Title Ad Valorem Tax (Tavt), Seresa'o Ivey, Richard Nkrumah, Tanner Perfect

Georgia Municipal Association Practicum (2013-2022)

No abstract provided.

Gma Financial Condition Project, Nick Archer, Bright Agbo, Carmisha Primus, Breana James, Jamie Bond, Christopher Suggs, Anna Mcintyre, Rebecca Sakyi

Georgia Municipal Association Practicum (2013-2022)

No abstract provided.

A Comparison Of Fiscal Conditions In Response To The Great Recession, Austin Hinkley, Miranda Bunch, Emily Stuchell, John Swett, Marshall Wingate

Georgia Municipal Association Practicum (2013-2022)

No abstract provided.

Carilee Coleman Park And Rountree Log Cabin, Tanner Perfect

Georgia Municipal Association Practicum (2013-2022)

No abstract provided.