Stigma And Its Reduction: The Role Of Knowledge, Causal Attribution, And Mental Disorder Type, Jesica N. Ferguson

Undergraduate Honors Thesis Projects

Abstract

Research has shown undeniable evidence of mental illness stigma. Stigma has been shown to reduce treatment seeking and negatively impact emotion and cognition in individuals with mental illness (Livingstone & Boyd, 2010). By discovering the driving forces behind stigma, treatment seeking and quality of life can be improved for individuals with mental illness. This study investigates the effect of knowledge, disorder type, and causal attribution on mental illness stigma. Specifically, participants were assigned to one of two conditions, knowledge or no knowledge. Knowledge conditions included information about a disorder (schizophrenia or depression, depending on disorder condition) such as definition, …

Characterization Of Two Cyclic Di-Gmp Phosphodiesterases Hypothesized To Regulate Virulence In Streptomyces Scabies, Madison Flasco

Undergraduate Honors Thesis Projects

Common scab is a devastating disease that affects the marketability of potatoes. The disease results in raised and pitted lesions seen on the surface of the potato and is caused by the soil pathogen, Streptomyces scabies. The S. scabies genome has two cyclic-di-GMP phosphodiesterases, RmdA and RmdB, both regulators of morphology and development. These proteins break down the ubiquitous second messenger molecule cyclic di-GMP, a molecule in charge of cell cycle progression and virulence. Both proteins contain diguanylate cyclase domains and phosphodiesterase domains, GGDEF and EAL, respectively, while RmdA contains an additional PAS_4 domain. Despite similar domain configurations, the two …

Towards Understanding The Role Of Small Mammals In The Transmission Of Lyme Disease In Virginia, Usa, Robert K. Rose, Laura Bitzer, Wayne Hynes, Holly D. Gaff, Robyn Nadolny, Jory Brinkerhoff

Biological Sciences Faculty Publications

Larvae and nymphs of many species of ticks select small mammals, reptiles, and birds as hosts. Since 2011, we have examined more than 1,000 small mammals of 10 species and collected a small tissue sample as well as all visible ticks; rates of infestation range from 18% in harvest mice to 53% in meadow voles. Identification of immature ticks is challenging and requires molecular or genetic methods beyond classification as being from the genus Ixodes or another genus. Ixodes ticks include Ixodes scapularis, the species that transmits the Lyme disease-causing bacterium Borrelia burgdorferi to humans. Of the approximately 2,300 ticks …

Modelling The Effects Of Habitat And Hosts On Tick Invasions, Robyn M. Nadolny, Holly D. Gaff

Biological Sciences Faculty Publications

Many tick species are invading new areas because of anthropogenic changes in the landscape, shifting climatic variables and increasing populations of suitable host species and tick habitat. However, the relative influences of habitat and hosts in tick dispersal and tick population establishment remain in question. A spatially explicit agent-based model was developed to explore the spatio-temporal dynamics of a generic tick population in the years immediately following the introduction of ticks into a novel environment. The general model was then adapted to investigate a case study of two recent tick species invasions into the Mid-Atlantic United States. The recent simultaneous …

“We Hide…”: Perceptions Of Hiv Risk Among Black And Latino Msm In New York City, Ashley Murray, Zaneta Gaul, Madeline Y. Sutton, Jose Nanin

Publications and Research

Black and Latino men who have sex with men (BLMSM) are disproportionately infected with HIV; they comprised 66% of HIV diagnoses among men who have sex with men (MSM) in the United States in 2015. Risk factors for HIV infection among BLMSM include a high community prevalence of diagnosed and undiagnosed HIV/STDs, and dense sex partner networks. Perceptions of HIV risk among BLMSM were explored to inform HIV prevention efforts. During 2011–2012, semistructured interviews were conducted with BLMSM in New York City. Using computer-assisted thematic analyses (NVivo), transcribed interview responses to questions regarding HIV risk for main themes were examined. …

Investigating The Status Of A Rare Cross-Linguistic Contrast: The Case Of Romanian Palatalized Postalveolars, Laura Spinu

Publications and Research

This study examines a rare cross-linguistic contrast, that between plain and secondarily palatalized postalveolar fricatives, through (i) an acoustic analysis of the production of 31 Romanian speakers, and (ii) a perception experiment with a different group of 31 native speakers. Evidence of acoustic separation between plain and palatalized forms was found for 27 of the subjects, suggesting that the contrast is produced by the majority. This is consistent with previous reports of native speakers collected in 1961. These findings were supported by the results of the perceptual experiment, which showed that native speakers exhibit moderate sensitivity to this contrast. An …

Two-Dimensional Maximal Repetitions, Amihood Amir, Gad M. Landau, Shoshana Marcus, Dina Sokol

Publications and Research

Maximal repetitions or runs in strings have a wide array of applications and thus have been extensively studied. In this paper, we extend this notion to 2-dimensions, precisely defining a maximal 2D repetition. We provide initial bounds on the number of maximal 2D repetitions that can occur in a matrix. The main contribution of this paper is the presentation of the first algorithm for locating all maximal 2D repetitions in a matrix. The algorithm is efficient and straightforward, with runtime O(n^2 log n log log n+ rho log n), where n^2 is the size of the input, and rho is …

Symposium On Buddhist Perspectives On Free Will: Agentless Agency?, Rick Repetti

Publications and Research

This special issue of the Journal of Buddhist Ethics, Volume 25, is a symposium on the anthology, Buddhist Perspectives on Free Will: Agentless Agency? (Repetti), and on the topic reflected by that title, more broadly, based on an Author Meets Critics session of the 2018 American Philosophical Association Eastern Division meeting organized by Christian Coseru. To orient readers new to the topic, I first sketch what some of the issues are regarding Buddhist perspectives on free will. Second, I briefly describe the anthology, and third, I introduce the several contributions to this symposium. As I am sympathetic to most …

Poster: Information Meeting For 9 To 5 Musical, University Of North Florida

Musical Theatre Club and Swoop Troupe Theatre Corporation Performances

UNF MTC Information Meeting for 9 to 5 the Musical on Thursday 9/14. Tech--6:30pm. Performance-7:30pm. Building 14D Room 1700

Effects Of Nonnative Rainbow Trout On Two Species Of Endemic Mexican Amphibians, A. B. Estrella Zamora, Geoffrey R. Smith, J. A. Lemos-Espinal, G. A. Woolrich-Pina, R. Montoya Ayala

Faculty Publications

No abstract provided.

The Social Amplification Of Haze-Related Risks On The Internet, Mark Chong, Murphy Choy

Research Collection Lee Kong Chian School Of Business

This study explores the implications of the digital network society for public health communication and management through an empirical study on communication related to the transboundary haze crisis in Singapore. Using the Social Amplification of Risk Framework (SARF), the authors applied sentiment and thematic analysis on haze-related posts on an online discussion forum (HardwareZone) and a social networking site (Facebook), as well as to haze-related articles in The Straits Times (a newspaper). The study shows that the medium matters in social amplification of risk: Facebook had an effect on the amplification of emotions while HardwareZone and Straits Times …

Advance Care Planning Documentation Strategies; Goals-Of-Care As An Alternative To Not-For-Resuscitation In Medical And Oncology Patients. A Pre-Post Controlled Study On Quantifiable Outcomes, David J.R Morgan, Derek Eng, Dominic Higgs, Maria Beilin, Caroline Bulsara, Milly Wong, Louise Angus, Nicholas Waldron

Nursing Papers and Journal Articles

Background: Health services in Tasmania, Victoria and now Western Australia are changing to goals-of-care (GOC) advance care planning (ACP) documentation strategies.

Aim: To compare the clinical impact of two different health department-sanctioned ACP documentation strategies.

Methods: A non-blinded, pre–post, controlled study over two corresponding 6-month periods in 2016 and 2017 comparing the current discretional not-for-resuscitation (NFR) with a new, inclusive GOC strategy in two medical/oncology wards at a large private hospital. Main outcomes were the uptake of ACP forms per hospitalisation and the timing between hospital admission, ACP form completion and in-patient death. Secondary outcomes included utilisation of the rapid …

Improving The Validity Of Script Concordance Testing By Optimising And Balancing Items, Michael Wan, Elina Tor, Judith Nicky Hudson

Medical Papers and Journal Articles

Background: A script concordance test (SCT) is a modality for assessing clinical reasoning. Concerns had been raised about the plausible validity threat to SCT scores if students deliberately avoided the extreme answer options to obtain higher scores. The aims of the study were firstly to investigate whether students’ avoidance of the extreme answer options could result in higher scores, and secondly to determine whether a ‘balanced approach’ by careful construction of SCT items (to include extreme as well as median options as model responses) would improve the validity of an SCT.

Methods: Using the paired sample t-test, the actual average …

Physicians' Perspectives On Clinical Pharmacy Services In Northern Sweden: A Qualitative Study, Charlotta Vinterflod, Maria Gustafsson, Sofia Mattsson, Gisselle Gallego

Medical Papers and Journal Articles

Background: In many countries, clinical pharmacists are part of health care teams that work to optimize drug therapy and ensure patient safety. However, in Sweden, clinical pharmacy services (CPSs) in hospital settings have not been widely implemented and regional differences exist in the uptake of these services. Physicians’ attitudes toward CPSs and collaborating with clinical pharmacists may facilitate or hinder the implementation and expansion of the CPSs and the role of the clinical pharmacist in hospital wards. The aim of this study was to explore physicians’ perceptions regarding CPSs performed at hospital wards in Northern Sweden.

Methods: Face-to-face semi-structured interviews …

Cost Analysis Of The Ctlb Study, A Multitherapy Antenatal Education Programme To Reduce Routine Interventions In Labour, Kate M. Levett, Hannah G. Dahlen, Caroline A. Smith, Kenneth William Finlayson, Soo Downe, Federico Girosi

Medical Papers and Journal Articles

Objective: To assess whether the multitherapy antenatal education ‘CTLB’ (Complementary Therapies for Labour and Birth) Study programme leads to net cost savings.

Design: Cost analysis of the CTLB Study, using analysis of outcomes and hospital funding data.

Methods: We take a payer perspective and use Australian Refined Diagnosis-Related Group (AR-DRG) cost data to estimate the potential savings per woman to the payer (government or private insurer). We consider scenarios in which the intervention cost is either borne by the woman or by the payer. Savings are computed as the difference in total cost between the control group and the study …

Carers' Preferences For The Delivery Of Therapy Services For People With Disability In Rural Australia: Evidence From A Discrete Choice Experiment, G Gallego, A Dew, M Lincoln, K Bulkeley, J Brentnall, C Vietch

Medical Papers and Journal Articles

Background: The implementation of the Australian National Disability Insurance Scheme (NDIS) is expected to generate a responsive, person-centred system that will empower people with disability to choose the services and support they receive. However little attention has been paid to examine how users of the NDIS will choose and spend their individual budgets. This study aimed to determine quantitatively the relative importance that carers of people with a disability living in rural Australia place on different therapy service delivery characteristics.

Methods: A stated preference discrete choice experiment (DCE) was incorporated into a survey of carers of people with disability living …

How Are Junior Doctors Managing Patients With Self-Limiting Illnesses At Their First Presentation? A Video Vignette Study, Eugene D'Souza, Catherine Krejany, Rosie Meng, Moyez Jiwa

Medical Papers and Journal Articles

Purpose: To conduct a video vignette survey of medical students and doctors investigating test ordering for patients presenting with self-limiting or minor illness.

Methods: Participants were shown six video vignettes of common self-limiting illnesses and invited to devise investigation and management plans for the patients’ current presentation. The number of tests ordered was compared with those recommended by an expert panel. A Theory of Planned Behaviour Questionnaire explored participants’ beliefs and attitudes about ordering tests in the context of self-limiting illness.

Results: Participants (n=61) were recruited from across Australia. All participants ordered at least one test that was not recommended …

Relaxation Techniques For Pain Management In Labour, C. Smith, K. Levett, C. Collins, H. Dahlen, M. Suganuma

Medical Papers and Journal Articles

Background: Many women would like to avoid pharmacological or invasive methods of pain management in labour and this may contribute to the popularity of complementary methods of pain management. This review examined currently available evidence on the use of relaxation therapies for pain management in labour. This is an update of a review first published in 2011.

Objectives: To examine the effects of mind-body relaxation techniques for pain management in labour on maternal and neonatal well-being during and after labour.

Search methods: We searched Cochrane Pregnancy and Childbirth’s Trials Register (9 May 2017), the Cochrane Central Register of Controlled Trials …

Massage, Reflexology And Other Manual Methods For Pain Management In Labour, C. Smith, K. Levett, C. Collins, H. Dahlen, C. Ee, M. Suganuma

Medical Papers and Journal Articles

Background

Many women would like to avoid pharmacological or invasive methods of pain management in labour, and thismay contribute towards the popularity of complementary methods of pain management. This review examined the evidence currently available on manual methods, including massage and reflexology, for pain management in labour. This review is an update of the review first published in 2012.

Objectives

To assess the effect, safety and acceptability of massage, reflexology and other manual methods to manage pain in labour.

Search methods

For this update, we searched Cochrane Pregnancy and Childbirth’s Trials Register (30 June 2017), the Cochrane Central Register of …

Impact Of Aging On The Auditory System And Related Cognitive Functions: A Narrative Review, Dona M.P Jayakody, Peter L. Friedland, Ralph N. Martins, Hamid R. Sohrabi

Medical Papers and Journal Articles

Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects approximately one-third of the world’s population. The peripheral and central hearing alterations associated with age-related hearing loss have a profound impact on perception of verbal and non-verbal auditory stimuli. The high prevalence of hearing loss in the older adults corresponds to the increased frequency of dementia in this population. Therefore, researchers have focused their attention on age-related central effects that occur independent of the peripheral hearing loss as well as central effects of peripheral hearing loss and its association with cognitive decline and dementia. Here we review the …

Actinomyces Cavernous Sinus Infection: A Case And Systematic Literature Review, Michal Lubomski, James Dalgliesh, Kenneth Lee, Omprakash Damodaran, Genevieve Mckew, Stephen Reddel

Medical Papers and Journal Articles

A 63-year-old man presented with a 2-month history of progressive right-sided exophthalmos, painful ophthalmoplegia and fevers. As more features developed, he was diagnosed with giant cell arteritis then Tolosa-Hunt syndrome and transiently responded to corticosteroids. A bland cerebrospinal fluid and highly metabolically active brain (18F)-fluoro-D-glucose-positron emission tomography suggested lymphoma. Biopsy of the mass showed sulphur granules with Gram-positive filamentous bacteria with Actinomyces-like colonies. Actinomyces cavernous sinus infections are rare and indolent. They often mimic non-infective causes including other inflammatory and infiltrative conditions, vascular and neoplastic causes, particularly lymphoma. Clinicians should consider infective cavernous sinus syndromes in people with a …

Informing Implementation Of Quality Improvement In Australian Primary Care, Charlotte Hespe, Lucie Rychetnik, David Peiris, Mark Harris

Medical Papers and Journal Articles

Background: Quality Improvement (QI) initiatives in primary care are effective at improving uptake of evidence based guidelines, but are difficult to implement and sustain. In Australia meso-level health organisations such as Primary health care Organisations (PHCO) offer new opportunities to implement area-wide QI programs. This study sought to identify enablers and barriers to implementation of an existing Australian QI program and to identify strategic directions that PHCOs can use in the ongoing development of QI in this environment.

Methods: Semi-structured telephone interviews were conducted with 15 purposively selected program staff and participants from the Australian Primary Care Collaborative (APCC) QI …

Risk Of Pelvic Inflammatory Disease In Relation To Chlamydia And Gonorrhea Testing, Repeat Testing, And Positivity: A Population-Based Cohort Study, Joanne Reekie, Basil Donovan, Rebecca Guy, Jane S. Hocking, John M. Kaldor, Donna B. Mak, Sallie Pearson, David Preen, Louise Stewart, James W.B Liu

Medical Papers and Journal Articles

Background: There is uncertainty around whether the risks of pelvic inflammatory disease (PID) differ following Chlamydia trachomatis (chlamydia) and Neisseria gonorrhoeae (gonorrhea) infection. We quantified the risk of PID associated with chlamydia and gonorrhea infection and subsequent repeat infections in a whole-population cohort.

Methods: A cohort of 315123 Western Australian women, born during 1974–1995, was probabilistically linked to chlamydia and gonorrhea testing records and to hospitalizations and emergency department presentations for PID from 2002 to 2013. Time-updated survival analysis was used to investigate the association between chlamydia and gonorrhea testing, and positivity, and risk of PID.

Results: Over 3199135 person-years, …

Using A Chronic Hepatitis B Registry To Support Population-Level Liver Cancer Prevention In Sydney, Australia, Monica C. Robotin, Ximena Masgoret, Mamta Porwal, David Goldsbury, Chee Khoo, Jacob George

Medical Papers and Journal Articles

Background: Approximately 1% of Australians have chronic hepatitis B (CHB), which disproportionately affects people born in hepatitis B-endemic countries. Currently, approximately half of the people affected remain undiagnosed and antiviral treatment uptake is suboptimal (~5%). This increases the likelihood of developing end-stage disease complications, particularly hepatocellular cancer (HCC), and largely accounts for the significant increases in HCC incidence and mortality in Australia over the last decades. As our previous economic modeling suggested that CHB screening and treatment is cost-effective, we tested the feasibility of a primary carebased model of CHB diagnosis and management to prevent HCC.

Materials and methods: From …

Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol Versus Fluticasone Furoate/Vilanterol Plus Umeclidinium Using Two Inhalers For Chronic Obstructive Pulmonary Disease: A Randomized Non-Inferiority Study, Peter R. Bremner, Ruby Birk, Noushin Brealey, Afisi S. Ismaila, Chang-Qing Zhu, David A. Lipson

Medical Papers and Journal Articles

Background: Single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62.5/25 μg has been shown to improve lung function and health status, and reduce exacerbations, versus budesonide/formoterol in patients with chronic obstructive pulmonary disease (COPD). We evaluated the non-inferiority of single-inhaler FF/UMEC/VI versus FF/VI + UMEC using two inhalers.

Methods: Eligible patients with COPD (aged ≥40 years; ≥1 moderate/severe exacerbation in the 12 months before screening) were randomized (1:1; stratified by the number of long-acting bronchodilators [0, 1 or 2] per day during run-in) to receive 24-week FF/UMEC/VI 100/62.5/25 μg and placebo or FF/VI 100/25 μg + UMEC 62.5 μg; all treatments/placebo were delivered using …

How Is Chaplaincy Marginalised-By Our Faith Communities And By Our Institutions And Can We Change It?, Jeffrey Cohen

Medical Papers and Journal Articles

This paper reviews the issues confronting chaplaincy/spiritual care in the 21st century. It looks at how faith communities are changing their view of chaplaincy as well how institutions respond. The paper looks at two qualitative studies and what can be learned from them in confronting the questions raised at the beginning. It concludes with the question of how the evidence base can be expanded to make chaplaincy/spiritual care more relevant over the next few years.

Effect Of Adjunctive Ranitidine For Antipsychotic-Induced Weight Gain: A Systematic Review Of Randomized Placebo-Controlled Trials, Xiaojing Gu, Rui Chen, Chen-Hui Sun, Wei Zheng, Xin-Hu Yang, Shi-Bin Wang, Gabor S. Ungvari, Chee Ng, Andrei Golenkov, Grace Lok, Lu Li, Ines Chow, Fei Wang, Yu-Tao Xiang

Medical Papers and Journal Articles

This study was a meta-analysis of randomized controlled trials (RCTs) of ranitidine as an adjunct for antipsychotic-induced weight gain in patients with schizophrenia. RCTs reporting weight gain or metabolic side effects in patients with schizophrenia were included. Case reports/series, nonrandomized or observational studies, reviews, and meta-analyses were excluded. The primary outcome measures were body mass index (BMI) (kg/m2) and body weight (kg). Four RCTs with five study arms were identified and analyzed. Compared with the control group, adjunctive ranitidine was associated with marginally significant reductions in BMI and body weight. After removing an outlier study for BMI, the effect of …

Pain Medicine Content, Teaching And Assessment In Medical School Curricula In Australia And New Zealand, Elspeth E. Shipton, Frank Bate, Raymond Garrick, Carole Steketee, Eric J. Visser

Medical Papers and Journal Articles

Background: The objective of pain medicine education is to provide medical students with opportunities to develop their knowledge, skills and professional attitudes that will lead to their becoming safe, capable, and compassionate medical practitioners who are able to meet the healthcare needs of persons in pain. This study was undertaken to identify and describe the delivery of pain medicine education at medical schools in Australia and New Zealand.

Method: All 23 medical schools in Australia and New Zealand in 2016 were included in this study. A structured curriculum audit tool was used to obtain information on pain medicine curricula including …

Cerebral Small Vessel Disease Burden Is Associated With Poststroke Depressive Symptoms: A 15-Month Prospective Study, Yan Liang, Yang-Kun Chen, Vincent C. Mok, De-Feng Wang, Gabor S. Ungvari, Winnie C. Chu, Hee-Ju Kang, Wai-Kwong Tang

Medical Papers and Journal Articles

Objective: All types of cerebral small vessel disease (SVD) markers including lacune, white matter hyperintensities (WMH), cerebral microbleeds, and perivascular spaces were found to be associated with poststroke depressive symptoms (PDS). This study explored whether the combination of the four markers constituting an overall SVD burden was associated with PDS.

Methods: A cohort of 563 patients with acute ischemic stroke were followed over a 15-month period after the index stroke. A score of _7 on the 15-item Geriatric Depression Scale was defined as clinically significant PDS. Scores of the four SVD markers ascertained on magnetic resonance imaging were summed …

Mobile Phone Dependence, Social Support And Impulsivity In Chinese University Students, Songli Mei, Jingxin Chai, Shi-Bin Wang, Chee H. Ng, Gabor S. Ungvari, Yu-Tao Xiang

Medical Papers and Journal Articles

This study examined the frequency of mobile phone dependence in Chinese university students and explored its association with social support and impulsivity. Altogether, 909 university students were consecutively recruited from a large university in China. Mobile phone use, mobile phone dependence, impulsivity, and social support were measured with standardized instruments. The frequency of possible mobile phone use and mobile phone dependence was 78.3% and 7.4%, respectively. Multinomial logistic regression analyses revealed that compared with no mobile phone dependence, possible mobile phone dependence was significantly associated with being male (p = 0.04, OR = 0.7, 95% CI: 0.4–0.98), excessive mobile phone …