Digital Commons Network^™

Charecterization Of The Innate Immune Response In The Rat Intervertebral Disc At The Tissue And Cellular Level, Matthew Guerreiro

Theses and Dissertations (Comprehensive)

Low back pain (LBP) affects up to 80% of the global population at some point during their life. The costs associated with LBP are estimated at $100 billion per year, putting significant strains on our healthcare system. As intervertebral disc (IVD) herniation is one of the major causes of LBP we decided to focus on herniation facilitated inflammatory responses, where damage caused by herniation triggers an innate immune response which likely results in pain, inflammation, and recruitment of specialized innate immune cells like macrophages to the affected area. Since the role of the inflammatory response is relatively uncharacterized in the …

The Influence Of Water Quality On Wetland-Associated Microbial Communities, Lindsey Clairmont

Theses and Dissertations (Comprehensive)

Within a wetland environment, bacteria in association with plant roots play a vital role in maintaining the health of freshwater ecosystems. In order to gain insight into the stability and processes occurring within natural and constructed wetland environments we need to develop a better understanding of the relationship between wetland plants, root-associated microbial communities and environmental factors. Human population growth and urbanization have resulted in greater contaminant loads (inorganic nutrients, fecal contamination etc.) entering our waterways. As such, we need a better understanding of how anthropogenic impacts influence the structure and function of the wetland-associated microbial communities that we rely …

Indigenous-Black Identity: Two Manuscripts Concerning Indigenous-Black Identity, Identity Formation, Mental Health, And Trauma, Ann Marie Beals

Theses and Dissertations (Comprehensive)

This thesis was written in the form of two different, yet similar stand-alone manuscripts. The overall premise of my thesis was the exploration of Indigenous-Black identity – Indigenous to both Turtle Island and the continent of Africa. This introduction to the thesis is to give an overview of my work and the manuscripts, and to provide information that is relevant to the understanding of the thesis that may not necessarily be required for manuscripts that are to be submitted for publication. Manuscript one, titled Indigenous-Black Identity, Mental Health, and Trauma explored, as the title suggests, concepts of Indigenous-Black identity regarding …

Learning To Read In English: Vocabulary Knowledge, Phonological Awareness In Relation To Oral Reading Fluency In Chinese-English Bilinguals, Michelle (Ruyun) Huo

Theses and Dissertations (Comprehensive)

Second language (L2) acquisition has received increasing interest due to the large number of people immigrating or learning an L2 (e.g., Statistics Canada, 2016). Word reading fluency has been found to be a strong predictor of text reading fluency and comprehension (Fuchs, Fuchs, Hosp & Jenkins, 2001). For people learning to read in L2, skills such as oral reading fluency serve as an indicator of overall reading competence in their L2. The current study examined oral reading fluency in relation to vocabulary knowledge, rapid naming (RAN) and phonological awareness in English and Mandarin in Chinese-English bilinguals. Participants included 40 Chinese-English …

Bas Bleus, Divorceuses, Deceitful Prostitutes Or “Live Allegories” Of Change? Parisian Working-Class Women And The Revolution Of 1848, Natasha A. Gardonyi

Theses and Dissertations (Comprehensive)

This thesis acts as both a history of the roles that Parisian working-class women played as writers, society members and insurgents during the revolutionary year of 1848, and an analysis of why they were vilified in the press as bas-bleus, divorceuses, deceitful prostitutes and more extensively as the individuals responsible for the failure of the revolution. It argues that women became “live allegories” of the changes that Paris was experiencing in the first half of the nineteenth century, particularly when a small minority of women radicalized from late April to June. These women galvanized anxieties that men and the upper …

The Complexity Of Canadian Anti-Communism, 1945-1967, Ian Muller

Theses and Dissertations (Comprehensive)

This dissertation argues that the history of anti-communism in English Canada between 1945 and 1967 is more diverse and complicated than traditionally acknowledged. Often dispersed throughout the scholarship as elements of other Cold War topics, including espionage, state surveillance, and policing, anti-communism is the central subject of this investigation. A series of case studies are used to analyze individual encounters with the state and civic engagement with the domestic threat of communism. The unique politico-cultural approach of this dissertation will bolster Canada’s Cold War historiography by investigating both public and private manifestations of anti-communism.

The intersections of public safety, the …

“Inconvenient Neighbours, Whom It Was Desirable Ultimately Wholly To Remove”: Differing Factors In The Dispossessions Of Studied Anishinaabe Groups Of The Great Lakes Basin, 1820-1865, Heather J. Sanguins

Theses and Dissertations (Comprehensive)

Despite being located within a relatively close geographic area, the Anishinaabeg of the eastern Great Lakes basin had different experiences of, and responses to, attempted and actual dispossession between 1820 and 1865. This research explores these experiences and the exercise of colonial power through the dispossession of six groups: the Lake Erie Anishinaabeg, the Walpole Anishinaabeg, the “American” Anishinaabeg who migrated into Upper Canada and Canada West, the Chippewa of Lakes Huron, Couchiching, and Simcoe, the Potaganasee Ojibwa of Drummond Island, and the Manitoulin Anishinaabeg. While eight themes weave their way through the cases, every case of attempted or actual …

Ecological Ethics And Social Work Therapy Practice, Karma Guindon

Theses and Dissertations (Comprehensive)

This study sheds light on the meaning of ecological ethics from the perspectives of ecologically-informed therapy professionals. A qualitative methodology was used to explore the perspectives of therapists from Canada, England, and the United States. Thirteen professionals were interviewed and feedback on these interviews was obtained utilizing focus groups. The findings include themes of relational assumptions, ecological values and principles, practice ecologies, and challenges and solutions to embracing ecological ethics. The findings suggest ways social work therapists can integrate ecological ethics into their everyday practice and point to changes that can be made in the profession more broadly, including changes …

Girls’ Voices Of The Eighteenth Century: The Development Of A Genre For Young Female Readers, 1740-1800, Sarah Rangaratnam

Theses and Dissertations (Comprehensive)

Just as they do today, adolescent girls functioned as a cultural force in the eighteenth century, and it was commercially viable for authors and publishers to attract and sustain the attention of these teenaged readers. Girls’ Voices of the Eighteenth Century: The Development of a Genre for Young Female Readers, 1740-1800, examines how four female authors leveraged elements of fairy tales, romances and gothic fiction, and developed dialogue and humour in their texts, to reflect the interests and literary awareness of their target audience of adolescent girls. My study begins with an investigation of the legacy of early French fairy …

A Qualitative Study Of Families’ Experiences With Food Insecurity In Addis Ababa, Ethiopia, Elias Omer

Theses and Dissertations (Comprehensive)

Ethiopia has shown considerable progress in alleviating the decades-long food insecurity problem, but still, in the context of urban areas such as Addis Ababa families continue to struggle to make ends meet. The overall purpose of this research is to explore families’ lived experiences and coping mechanisms with food insecurity. Framed with the narrative-empowerment theoretical framework this ethnographic study outlines the findings of semi-structured interviews and focus group discussion of 35 adults and children and observational notes. Participants were able to tell their perception, causes, and impacts of food insecurity in their families. They outlined the daily strategies they employ …

Arriving Somewhere, Not Here: Exploring And Mapping The Relationship Between Border Enforcement And Migration By Boat In The Central Mediterranean Sea, 2006 To 2015, Kira Williams

Theses and Dissertations (Comprehensive)

The European Union (EU) implemented a maritime interdiction network using search and rescue which interdicted at least 462,813 “illegal migrants” in the Central Mediterranean Sea between 2006 and 2015. This involved 15 discrete, militarised and semi-secret maritime interdiction operations (MIOs) at a minimum cost of 126.9 million 2014 Euros. In this dissertation, I will explore and map these operations and their geographies between 2006 and 2015.

First, and based on the given existence of the European Patrols Network, I examine how this network came into being in the first place. This serves to show that the EU purposely created regular …

Factors Impacting Former Ffa Members’ Decision To Discontinue Ffa After High School, Danielle Eve-Marie Sanok, Christopher T. Stripling, Carrie A. Stephens, Andrew P. Griffith

Journal of Research in Technical Careers

The purpose of this study was to explore the factors impacting former National FFA Organization (FFA) members’ decision to discontinue FFA membership after high school. Data were collected using focus groups. Data indicated areas of improvement for how to retain membership on the alumni level within colleges and other local FFA Alumni chapters. Participants noted a lack of advertising from the FFA during their high school experience, and this may partially explain why FFA loses a majority of its membership after high school. Additionally, advisors played an influential role in deciding not to continue with FFA, and participants expressed a …

Coscarelli V. Esquared, Southern District Of New York

Historical and Topical Legal Documents

No abstract provided.

A Practitioner's View Of Institutional Corruption Through The Lens Of The Health Care System: An Essay, Reuben Guttman

Emory Business Law Review

I cannot say the root of my cynicism stems solely from my litigation against the healthcare industry. I spent years representing industrial and service unions and their members; the average working person'or hardcore union member'has no allusions about the power of institutions to corrupt. They often view their own employer and their union with the same gimlet eye. Yet, my litigation against the healthcare industry has, at the very least, been a policy laboratory for the understanding of institutional wrongdoing and deficiencies in compliance enforcement. While the lessons I have learned are in the first instance about 'fraud, waste and …

Effective Compliance Means Imposing Individual Liability, Reuben A. Guttman

Emory Business Law Review

Deputy Attorney General Sally Yates said it in a memo dated September 9, 2015, and her successor, Rod Rosenstein, said it in remarks dated October 6, 2017: corporations act through individuals, and compliance enforcement must necessarily account for holding individuals liable for the wrongs they orchestrate under cover of the corporate umbrella. The logic is reasonable and necessary. We blame corporations for catastrophic environmental events, misbranded drugs that cause injury, and financial products that destroy the life savings of those who have toiled for a living; yet at the helm of the corporations'guiding their path of impropriety'are people, many of …

Runnable, Ruinable Repo And The Great Recession: A Panic-Proofing Approach To Financial Regulation, Aaron Metviner

Emory Business Law Review

This Paper argues for a sort of Gorton/Ricks hybrid approach to panic-proofing, whereby the federal government (1) insures the very-short-term repo obligations of the SIFIs (while also ensuring the high-quality of the collateral under those repo agreements) and (2) limits the exposure levels of the SIFIs to all other forms of uninsured runnable debt.

Burnout-Depression Overlap: Nomological Network Examination And Factor-Analytic Approach, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

Burnout has been defined as a condition in which individuals are left exhausted by a long-term confrontation with unmanageable job stressors. The question of whether burnout reflects anything other than depressive responses to unresolvable stress remains an object of debate. In this 911-participant study (83% female; mean age: 42.36), we further addressed the issue of burnout-depression overlap. Burnout was assessed with the exhaustion subscale of the Maslach Burnout Inventory-General Survey (MBI-GS) and depression with the PHQ-8. The relationships of burnout and depression with three jobrelated variables – illegitimate work tasks, work-nonwork interference, and job satisfaction – and three “context-free” variables …

The Silencing Of The Knowledge-Base In Early Childhood Education And Care Professionalism, Vjg Campbell Barr

School of Law, Humanities and Social Sciences

No abstract provided.

The Role Of Felt Or Enacted Criticism In Parents’ Decision Making In Differing Contexts And Communities: Toward A Formal Grounded Theory, Sarah J. Neill, Imelda Coyne

School of Nursing and Midwifery

Felt or enacted criticism was identified as a significant influence on White British parents’ decision making during acute childhood illness in a substantive grounded theory “Containing acute childhood illness within family life.” These parents sought to avoid further criticism, sometimes leading to delayed consultation. Using Glaserian grounded theory principles, we conducted a secondary analysis of data from three studies, to establish the transferability and modifiability of the original theory to other settings and communities in Ireland and England. Felt or enacted criticism was found to operate across the childhood age range, social groups, and settings. Parent’s strategies to avoid criticism …

Differential Phosphorylation And N-Terminal Configuration Of Capsid Subunits In Parvovirus Assembly And Viral Trafficking, J Gil-Ranedo, E Hernando, N Valle, L Riolobos, B Maroto, Jm Almendral

Peninsula Medical School

No abstract provided.

Moor Health And Wellbeing. An Evaluation Of Two National Park Projects: Dartmoor Naturally Healthy And Exmoor Moor To Enjoy., Se Howes, A Edward-Jones, S Waite

School of Nursing and Midwifery

No abstract provided.

The British Neurosurgical Trainee Research Collaborative: Five Years On, Aswin Chari, Aimun A. Jamjoom, Ellie Edlmann, Aminul I. Ahmed, Ian C. Coulter, Ruichong Ma, Paul May, Paul M. Brennan, Peter J.A. Hutchinson, Angelos G. Kolias

Peninsula Medical School

No abstract provided.

The Effectiveness Of The Inspiring Futures Parenting Programme In Improving Behavioural And Emotional Outcomes In Primary School Children With Behavioural Or Emotional Difficulties: Study Protocol For A Randomised Controlled Trial, Nick Axford, Georgina Warner, Tim Hobbs, Sarah Heilmann, Anam Raja, Vashti Berry, Obioha C. Ukoumunne, Justin Matthews, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, Tom Wilkinson, Luke Timmons, Gretchen Bjornstad

Peninsula Medical School

No abstract provided.

The Effectiveness Of Chance Uk’S Mentoring Programme In Improving Behavioural And Emotional Outcomes In Primary School Children With Behavioural Difficulties: Study Protocol For A Randomised Controlled Trial, Laura Whybra, Georgina Warner, Gretchen Bjornstad, Tim Hobbs, Lucy Brook, Zoe Wrigley, Vashti Berry, Obioha C. Ukoumunne, Justin Matthews, Rod Taylor, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, Nick Axford

Peninsula Medical School

No abstract provided.

Impact Of The Sign Head Injury Guidelines And Nhs 4-Hour Emergency Target On Hospital Admissions For Head Injury In Scotland: An Interrupted Times Series, Carl Marincowitz, Fiona E. Lecky, Eleanor Morris, Victoria Allgar, Trevor A. Sheldon

Peninsula Medical School

ObjectivesHead injury is a common reason for emergency department (ED) attendance. Around 1% of patients have life-threatening injuries, while 80% of patients are discharged. National guidelines (Scottish Intercollegiate Guidelines Network (SIGN)) were introduced in Scotland with the aim of achieving early identification of those with acute intracranial lesions yet safely reducing hospital admissions.This study aims to assess the impact of these guidelines and any effect the national 4-hour ED performance target had on hospital admissions for head injury.SettingAll Scottish hospitals between April 1998 and March 2016.ParticipantsPatients admitted to hospital for head injury or traumatic brain injury (TBI) diagnosed by CT …

Prospective Subgroup Analyses Of The Randomized Mcl‐002 (Sprint) Study: Lenalidomide Versus Investigator's Choice In Relapsed Or Refractory Mantle Cell Lymphoma, L Arcaini, T Lamy, J Walewski, D Belada, Et Al

Peninsula Medical School

In the mantle cell lymphoma (MCL)-002 study, lenalidomide demonstrated significantly improved median progression-free survival (PFS) compared with investigator's choice (IC) in patients with relapsed/refractory MCL. Here we present the long-term follow-up data and results of preplanned subgroup exploratory analyses from MCL-002 to evaluate the potential impact of demographic factors, baseline clinical characteristics and prior therapies on PFS. In MCL-002, patients with relapsed/refractory MCL were randomized 2:1 to receive lenalidomide (25 mg/day orally on days 1–21; 28-day cycles) or single-agent IC therapy (rituximab, gemcitabine, fludarabine, chlorambucil or cytarabine). The intent-to-treat population comprised 254 patients (lenalidomide, n = 170; IC, n = …

Use Of A Patient Centered Transitional Care Program To Decrease Hospitalization In Adults With Heart Failure And/Or Copd, Mouline Guerrier

Electronic Theses and Dissertations 2010 - 2019

No abstract provided.

Identifying Enablers And Barriers To Individually Tailored Prescribing: A Survey Of Healthcare Professionals In The Uk, Joanne Reeve, Nicky Britten, Richard Byng, Jo Fleming, Janet Heaton, Janet Krska

Peninsula Medical School

No abstract provided.

Patient-Reported Outcomes With Initiation Of Fluticasone Furoate/Vilanterol Versus Continuing Usual Care In The Asthma Salford Lung Study, H Svedsater, R Jones, N Bosanquet, L Jacques, J Lay-Flurrie, Da Leather, J Vestbo, S Collier, A Woodcock

Peninsula Medical School

No abstract provided.

Community Resilience In Rural China: The Case Of Hu Village, Sichuan Province, G Wilson, Z Hu, S Rahman

School of Geography, Earth and Environmental Sciences

Building on conceptual frameworks to assess community resilience developed by Emery and Flora (2006) and Kelly et al. (2015), this study analyses the resilience of Hu village (Sichuan, China). The resilience of the village is assessed in the face of multiple and complex slow- and fast onset anthropogenic disturbances, especially the impacts of globalisation and modernisation, which have substantially transformed Chinese society. Hu village is typical for a rural community in transition affected by industrialisation, deagrarianisation, counter-urbanisation and changing stakeholder expectations and opportunities. This has been accompanied by agricultural depopulation, outmigration, increasing non-farm employment, declining agricultural incomes, and associated social …