Digital Commons Network^™

Repetitive Transcranial Electrical Stimulation Induces Quantified Changes In Resting Cerebral Perfusion Measured From Arterial Spin Labeling, Matthew Sherwood, Aaron T. Madaris, Casserly R. Mullenger, R. Andy Mckinley

Neuroscience, Cell Biology & Physiology Faculty Publications

The use of transcranial electrical stimulation (TES) as a method to augment neural activity has increased in popularity in the last decade and a half. The specific application of TES to the left prefrontal cortex has been shown to produce broad cognitive effects; however, the neural mechanisms underlying these effects remain unknown. In this work, we evaluated the effect of repetitive TES on cerebral perfusion. Stimulation was applied to the left prefrontal cortex on three consecutive days, and resting cerebral perfusion was quantified before and after stimulation using arterial spin labeling. Perfusion was found to decrease significantly more in a …

Montana Kaimin, September 5, 2018, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

09-05-2018 Swosu's Parents Day Is September 15, Southwestern Oklahoma State University

THE BARK ARCHIVE 2018

Many activities are planned for Parents Day 2018 at Southwestern Oklahoma State University in Weatherford on Saturday, September 15.

Managing The Risks And Rewards Of Death In Eusocial Insects, Qian Sun, Kenneth F. Haynes, Xuguo Zhou

Faculty Publications

Eusocial insects frequently face death of colony members as a consequence of living in large groups where the success of the colony is not dependent on the fate of the individual. Whereas death of conspecifics commonly triggers aversion in many group-living species due to risk of pathogens, eusocial insects perform cooperative corpse management. The causes and social context of the death, as well as feeding and nesting ecology of the species, influence the way that corpses are treated. The corpse itself releases cues that dictate the colony's response. As a result, social insects exhibit behavioural responses that promote disease resistance, …

The Lumberjack, September 05, 2018

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University

The Lumberjack, September 05, 2018

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

September 5, 2018, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

New Unh Research Aims To Help Humans Survive Dehydration, Erika Mantz

Media Relations

No abstract provided.

Genetic Determinants Of Telomere Length In African American Youth, Andrew M. Zeiger, Marquitta J. White, Celeste Eng, Sam S. Oh, Jonathan Witonsky, Pagé C. Goddard, Maria G. Contreras, Jennifer R. Elhawary, Donglei Hu, Angel C. Y. Mak, Eunice Y. Lee, Kevin L. Keys, Lesly-Anne Samedy, Oona Risse Adams, Joaquín Magaña, Scott Huntsman, Sandra Salazar, Adam Davis, Kelley Meade, Emerita Brigino-Buenaventura, Michael A. Lenoir, Harold J. Farber, Kirsten Bibbins-Domingo, Luisa N. Borrell, Esteban G. Burchard

Publications and Research

Telomere length (TL) is associated with numerous disease states and is affected by genetic and environmental factors. However, TL has been mostly studied in adult populations of European or Asian ancestry. These studies have identified 34 TL-associated genetic variants recently used as genetic proxies for TL. The generalizability of these associations to pediatric populations and racially diverse populations, specifically of African ancestry, remains unclear. Furthermore, six novel variants associated with TL in a population of European children have been identified but not validated. We measured TL from whole blood samples of 492 healthy African American youth (children and adolescents between …

Interfering With Dna Decondensation As A Strategy Against Mycobacteria, Enzo M. Scutigliani, Edwin R. Scholl, Anita E. Grootemaat, Sadhana Khanal, Jakub A. Kochan, Przemek M. Krawczyk, Eric A. Reits, Atefeh Garzan, Huy X. Ngo, Keith D. Green, Sylvie Garneau-Tsodikova, Jan M. Ruijter, Henk A. Van Veen, Nicole N. Van Der Wel

Pharmaceutical Sciences Faculty Publications

Tuberculosis is once again a major global threat, leading to more than 1 million deaths each year. Treatment options for tuberculosis patients are limited, expensive and characterized by severe side effects, especially in the case of multidrug-resistant forms. Uncovering novel vulnerabilities of the pathogen is crucial to generate new therapeutic strategies. Using high resolution microscopy techniques, we discovered one such vulnerability of Mycobacterium tuberculosis. We demonstrate that the DNA of M. tuberculosis can condense under stressful conditions such as starvation and antibiotic treatment. The DNA condensation is reversible and specific for viable bacteria. Based on these observations, we hypothesized …

Author Correction: Evolutionary History Of Plant Hosts And Fungal Symbionts Predicts The Strength Of Mycorrhizal Mutualism, Jason Hoeksema, James D. Bever, Sounak Chakraborty, V. Bala Chaudhary, Monique Gardes, Catherine A. Gehring, Miranda M. Hart, Elizabeth A. Housworth, Wittaya Kaonongbua, John N. Klironomos, Marc J. Lajeunesse, James Meadow, Brook G. Milligan, Bridget J. Piculell, Anne Pringle, Megan A. Rúa, James Umbanhowar, Wolfgang Viechtbauer, Yen‐Wen Wang, Gail W. T. Wilson

Faculty and Student Publications (Open Access)

No abstract provided.

Genetically Determined Fungal Pathogen Tolerance And Soil Variation Influence Ectomycorrhizal Traits Of Loblolly Pine, Bridget Piculell, Lori G. Eckhardt, Jason D. Hoeksema

Faculty and Student Publications (Open Access)

No abstract provided.

The Parthenon, September 5, 2018, Sadie Helmick, Sarah Ingram, Rick Farlow, Franklin Norton, Heather Barker

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2018 Fall semester, the newspaper is only published one day a week. The editorial staff is responsible for the news and the editorial content.

Comparison Of Six Artificial Diets For Western Corn Rootworm Bioassays And Rearing, Lisa N. Meihls, Man P. Huynh, Dalton C. Ludwick, Thomas A. Coudron, B. Wade French, Kent S. Shelby, Andrea J. Hitchon, Jocelyn L. Smith, Art W. Schaafsma, Adriano E. Pereira, B. E. Hibbard

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The western corn rootworm, Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae), is considered the most important maize (Zea mays L.) pest in the U.S. Corn Belt. Bioassays testing susceptibility to Bacillus thuringiensis Berliner (Bt) and other toxins of corn rootworm larvae often rely on artificial diet formulations. Successful bioassays on artificial diet for corn rootworm have sometimes been challenging because of microbial contamination. Toward the long-term goal of developing a universal artificial diet for western corn rootworm larvae, we compared larval survival, dry weight, and percentage of molt in 10-d bioassays from six current diets of which we were aware. In …

Radiation Effects In Metal Oxides And Carbides, Benjamin Jackson Cowen

Nuclear Engineering ETDs

MD simulations of SiO₂, TiO₂, Cr₂O₃, Al₂O₃, MgO, and SiC, are performed to: (a) calculate TDE probability distributions and dependence on crystallographic direction, and (b) determine the number and types of defects formed with low- and high-energy PKAs and projectiles. In addition, a qualitative comparison of the MD simulation results of radiation damage in TiO₂, MgO, and crystalline and amorphous SiC thin films are compared with those of in situ TEM ion beam irradiation experiments at the Sandia National Laboratories’ I³TEM facility.

The TDE …

Selective Habitat Use By Moose During Critical Periods In The Winter Tick Life Cycle, Christine Healy, Peter J. Pekins, Lee Kantar, Russell G. Congalton, Shadi Atallah

Faculty Publications

High calf mortality attributed to winter tick (Dermacentor albipictus) parasitism occurs in moose (Alces alces) populations along their southern range in the northeastern United States. We analyzed habitat use of cow and calf moose during the critical drop-off and questing periods in the winter tick life cycle to determine a potential relationship between tick density and habitat. We measured habitat use using geospatial analyses of locational data from > 200 radio-marked animals at 3 sites in New Hampshire and Maine. Moose selected for optimal habitat, defined as 4–16 year-old forest openings, regardless of season or site; this was the only land …

Association Of Essential Tremor And Parkinson’S Disease Development, Alexander Gosch, Mary David

Journal of Undergraduate Research

Essential tremor (ET) is a neurological disorder characterized by symmetrical tremor of the upper limbs. Parkinson’s disease (PD) is a similar disorder, also characterized by tremor, with a few differences: ET tremor is mostly seen during action, while PD tremor is more prevalent while at rest. PD is characterized by problems with walking and balance, while ET is characterized primarily by tremor without balance problems. PD symptoms generally improve with the use of the drug levodopa while ET responds better to the drugs propranolol and primidone.

Examining How The Cd5 Co-Receptor Alters T Helper Cell Activation In Response To Bacterial Infection, Garrett Hamblin, Scott Weber

Journal of Undergraduate Research

Properly functioning helper T cells are crucial in a response to an infection. The adaptive immune response is orchestrated by T helper cells and their function is dependent upon interactions between the T cell receptor (TCR), peptide MHC (pMHC) and co-receptors. Upon TCR interaction with a foreign antigen, a calcium signaling cascade is initiated, which determines T cell activation, survival, proliferation and differentiation. CD5 is a T cell co-receptor that is a negative regulator of T cell activation. T cells with higher CD5 expression respond better to foreign antigen than those with lower CD5 expression. Cell-surface expression of CD5 is …

Is Mafb Essential To Β-Cell Growth And Proliferation?, Aaron Leifer, Jeffery Tessem

Journal of Undergraduate Research

Project Purpose: Our goal is to determine if MafB is necessary for β Cell proliferation and glucose stimulated insulin secretion (GSIS). Project Importance: Approximately 29.1 million people are affected by type 1 or type 2 diabetes in the United States, according to 2014 National Diabetes Statistic Report. In addition, these 29.1 spent or lost 245 billion dollars combined. A cure for diabetes would result in not only a better life style but would also save billions of dollars. Project Profile Body: Both forms of diabetes are ultimately caused by decreased functional β-cell mass. β-cell transplantation is a possible treatment for …

Little Lasting Impact Of The Paleocene-Eocene Thermal Maximum On Shallow Marine Molluscan Faunas, Linda Ivany, Carlie Pietsch, John Handley, Rowan Lockwood, Warren Allmon, Jocelyn Sessa

Faculty Publications

Global warming, acidification, and oxygen stress at the Paleocene-Eocene Thermal Maximum (PETM) are associated with severe extinction in the deep sea and major biogeographic and ecologic changes in planktonic and terrestrial ecosystems, yet impacts on shallow marine macrofaunas are obscured by the incompleteness of shelf sections. We analyze mollusk assemblages bracketing (but not including) the PETM and find few notable lasting impacts on diversity, turnover, functional ecology, body size, or life history of important clades. Infaunal and chemosymbiotic taxa become more common, and body size and abundance drop in one clade, consistent with hypoxia-driven selection, but within-clade changes are not …

Synthesis And Evaluation Of 4-Cycloheptylphenols As Selective Estrogen Receptor-Β Agonists (Serbas), K. L. Iresha Sampathi Perera, Alicia M. Hanson, Sergey V. Lindeman, Andrea Imhoff, Xingyun Lu, Daniel S. Sem, William A. Donaldson

Chemistry Faculty Research and Publications

A short and efficient route to 4-(4-hydroxyphenyl)cycloheptanemethanol was developed, which resulted in the preparation of a mixture of 4 stereoisomers. The stereoisomers were separated by preparative HPLC, and two of the stereoisomers identified by X-ray crystallography. The stereoisomers, as well as a small family of 4-cycloheptylphenol derivatives, were evaluated as estrogen receptor-beta agonists. The lead compound, 4-(4-hydroxyphenyl)cycloheptanemethanol was selective for activating ER relative to seven other nuclear hormone receptors, with 300-fold selectivity for the β over α isoform and with EC₅₀ of 30–50 nM in cell-based and direct binding assays.

Librarian's Report-9-5-2018, Georgia Southern University

Faculty Senate: Librarian's Reports

No abstract provided.

Criminal Justice And Criminology News, Georgia Southern University

Criminal Justice & Criminology: News & Publications (2012-2023)

• Assistant Criminal Justice Professor, Dr. Jonathan Grubb, Invited to Speak on Human Trafficking

Synthesis And Characterization Of Controlled Nitric Oxide Release From S-Nitroso-N-Acetyl-D-Penicillamine Covalently Linked To Polyvinyl Chloride (Snap-Pvc), Sean Hopkins, Megan C. Frost

Michigan Tech Publications, Part 1

Polyvinyl chloride (PVC) is one of the most widely used polymers in medicine but has very poor biocompatibility when in contact with tissue or blood. To increase biocompatibility, controlled release of nitric oxide (NO) can be utilized to mitigate and reduce the inflammatory response. A synthetic route is described where PVC is aminated to a specified degree and then further modified by covalently linking S-nitroso-N-acetyl-d-penicillamine (SNAP) groups to the free primary amine sites to create a nitric oxide releasing polymer (SNAP-PVC). Controllable release of NO from SNAP-PVC is described using photoinitiation from light emitting diodes (LEDs). Ion-mediated NO release is …

Out Of The Box: Relationship Between Incoming Computer Science Students’ Perceived Needs And Their Academic Performance In Core Courses, Xintong Zheng, Rebecca Wasserott

The Journal of Purdue Undergraduate Research

No abstract provided.

Design And Validation Of A Pressure-Based Flow Rate Soft Sensor For Freeze-Drying, Pasita Pibulchinda

The Journal of Purdue Undergraduate Research

No abstract provided.

Using Bone Lead As A Biomarker For Lead Toxicity In Condors: Accuracy Of Portable L-X- Ray Fluorescence (Lxrf) Device To Quantify Lead (Pb) In Condor Bone In Vivo, Emma Wallens

The Journal of Purdue Undergraduate Research

Our lab has been working on the development of a portable L- shell x-ray fluorescence (LXRF) device to quantify lead in bone in human in vivo. The purpose of this project is to determine the accuracy of the portable LXRF machine in measuring the lead content of condor bones in vivo. While the K-shell x-ray fluorescence (KXRF) machine is the most accurate machine to measure lead content in vivo because it has sufficient energy to overcome soft tissue attenuation, it is not very practical for use in a research lab with animals or for researchers covering a large migratory territory …

Talking In Whispers: How School Leaders Approach And Discuss Race, Caleb Hettinger

The Journal of Purdue Undergraduate Research

This study seeks to better understand how school administrators approach and discuss issues of race and racism in K–12 schools. Police shootings, the 2016 election, and riots across America have put race at the center of conversations, but many school administrators avoid discussing these issues in professional settings to avoid tension. Existing school leaders were surveyed to determine their attitudes and perceptions of racial dialogue. Findings indicate that school leaders report being willing and comfortable in discussing race. However, administrators also reported that they avoid these discussions unless prompted. Implications from this work suggest a need to better prepare school …

Perils Of Hollywood Whitewashing?: A Review Of 'Ghost In The Shell' Movie, Kosuke Mizukoshi

Markets, Globalization & Development Review

'Ghost in the Shell' was first produced as a Japanese animated film in 1995. The movie and its sequels established a cult status due to the philosophical depth in portraying the posthuman condition. It was remade as a live action Hollywood film in 2017; and this version failed at the box office. One reason had to be the “whitewashing” issue – that the female protagonist was played by a white actress in the Hollywood movie, rather than a Japanese character as in the original anime. This review essay critically discusses issues of whitewashing, racial ‘identity’, the shifting identity of the …

Caregiving In Sub-Saharan Africa And Older, Female Caregivers In The Era Of Hiv/Aids: A Namibian Perspective, Eveline N. Kalomo, Fred H. Besthorn

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

The human immunodeficiency virus (HIV) and the acquired immune deficiency syndrome (AIDS) have created an unprecedented ‘orphan crisis’ in sub-Saharan Africa. They have had a devastating impact on elder caregivers. Over 60% of children affected by HIV/AIDS are being care for by aging, often impoverished, grandmothers (AVERT, 2015). Yet there is a dearth of empirical work on the devastating impact of this pandemic on grandmothers. This article offers an overview of the literature with respect to what is currently known about caregivers generally and, specifically, older caregivers of orphans and vulnerable children (OVC) in sub-Saharan Africa. It addresses emerging policy …