Digital Commons Network^™

Unravelling The Structure Of Glycosyl Cations Via Cold-Ion Infrared Spectroscopy, Eike Mucha, Mateusz Marianski, Fei-Fei Xu, Daniel A. Thomas, Gerard Meijer, Gert Von Helden, Peter H. Seeberger, Kevin Pagel

Publications and Research

Glycosyl cations are the key intermediates during the glycosylation reaction that covalently links building blocks during the synthetic assembly of carbohydrates. The exact structure of these ions remained elusive due to their transient and short-lived nature. Structural insights into the intermediate would improve our understanding of the reaction mechanism of glycosidic bond formation. Here, we report an in-depth structural analysis of glycosyl cations using a combination of cold-ion infrared spectroscopy and first-principles theory. Participating C2 protective groups form indeed a covalent bond with the anomeric carbon that leads to C1-bridged acetoxonium-type structures. The resulting bicyclic structure strongly distorts the ring, …

System And Method For Automated Stereology Of Cancer, Peter Randolph Mouton, Dmitry Goldgof, Lawrence O. Hall, Baishali Chaudhury

USF Patents

This invention relates to a system and method for applying an ensemble of segmentations to microscopy images of a tissue sample to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations is applied to a plurality of greyscale or color microscopy images to generate a final image level segmentation and a final blob level segmentation. The final image level segmentation and final blob level segmentation are used to calculate a mean nuclear volume to determine if the tissue sample is representative of cancerous tissue.

The Role Of Inflammation And Immune Cells In Blood Flow Restriction Training Adaptation: A Review, Fabrício Eduardo Rossi, Marcelo Conrado De Freitas, Nelo Eidy Zanchi, Fábio Santos Lira, Jason M. Cholewa

Kinesiology

Blood flow restriction (BFR) combined with low-intensity strength training has been shown to increase skeletal muscle mass and strength in a variety of populations. BFR results in a robust metabolic stress which is hypothesized to induce muscle growth via increased recruitment of fast-twitch muscle fibers, a greater endocrine response, and/or enhancing the cellular swelling contribution to the hypertrophic process. Following exercise, neutrophils are the first immune cells to initiate the tissue remodeling process via several mechanisms including an increased production of cytokines and recruitment of monocytes/macrophages, which facilitate the phagocytosis of foreign particles, the differentiation of myoblasts, and the formation …

The Limbic System And Christian Sanctification, Tony N. Jelsma

Faculty Work Comprehensive List

"Even when our limbic system conveys strong motivations to act in a particular way, we still have the ability and responsibility to think and act in a manner that pleases God."

Posting about the complexity of the human brain from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/the-limbic-system-and-christian-sanctification/

Effects Of Coumaphos And Imidacloprid On Honey Bee (Hymenoptera: Apidae) Lifespan And Antioxidant Gene Regulations In Laboratory Experiments, Ales Gregorc, Mohamed Alburaki, Nicholas Rinderer, Blair Sampson, Patricia R. Knight, Shahid Karim, John Adamczyk

Faculty Publications

The main objective of this study was to test comparatively the effects of two common insecticides on honey bee Apis mellifera worker’s lifespan, food consumption, mortality, and expression of antioxidant genes. Newly emerged worker bees were exposed to organophosphate insecticide coumaphos, a neonicotinoid imidacloprid, and their mixtures. Toxicity tests were conducted along with bee midgut immunohistological TUNEL analyses. RT-qPCR assessed the regulation of 10 bee antioxidant genes linked to pesticide toxicity. We tested coumaphos at 92,600 ppb concentration, in combination with 5 and 20 ppb imidacloprid. Coumaphos induced significantly higher bee mortality, which was associated with down regulation of catalase …

Carbon Stocks And Accumulation Rates In Red Sea Seagrass Meadows, Oscar Serrano, Hanan Almahasheer, Carlos M Duarte, Xabier Irigoien

Research outputs 2014 to 2021

Seagrasses play an important role in climate change mitigation and adaptation, acting as natural CO₂ sinks and buffering the impacts of rising sea level. However, global estimates of organic carbon (C_org) stocks, accumulation rates and seafloor elevation rates in seagrasses are limited to a few regions, thus potentially biasing global estimates. Here we assessed the extent of soil C_org stocks and accumulation rates in seagrass meadows (Thalassia hemprichii, Enhalus acoroides, Halophila stipulacea, Thalassodendrum ciliatum and Halodule uninervis) from Saudi Arabia. We estimated that seagrasses store 3.4 ± 0.3 kg C_{org …}

Proliferating Cell Nuclear Antigen Interacts With The Crl4 Ubiquitin Ligase Subunit Cdt2 In Dna Synthesis-Induced Degradation Of Cdt1, Feng Leng, Lovely Saxena, Nam Hoang, Chunxiao Zhang, Logan Lee, Wenjing Li, Xiaoshan Gong, Fei Lu, Hong Sun, Hui Zhang

Chemistry and Biochemistry Faculty Research

During DNA replication or repair, the DNA polymerase cofactor, proliferating cell nuclear antigen (PCNA), homotrimerizes and encircles the replicating DNA, thereby acting as a DNA clamp that promotes DNA polymerase processivity. The formation of the PCNA trimer is also essential for targeting the replication-licensing protein, chromatin-licensing, and DNA replication factor 1 (CDT1), for ubiquitin-dependent proteolysis to prevent chromosomal DNA re-replication. CDT1 uses its PCNA-interacting peptide box (PIP box) to interact with PCNA, and the CRL4 E3 ubiquitin ligase subunit CDT2 is recruited through the formation of PCNA–CDT1 complexes. However, it remains unclear how CDT1 and many other PIP box–containing proteins …

How Wide Is Wide Enough?: Science, Values, And Law In Riparian Habitat Conservation, George Wilhere, Timothy Quinn

Natural Resources Journal

Difficult environmental policy issues often elicit fervent declarations to “follow the science.” Such declarations ignore the essential role of values in policy making. The main purpose of this article is to clarify the relationships among science, values, and law in environmental policy. An important policy issue in wildlife conservation, is determining “how much is enough?” That is, what is the smallest amount of habitat or minimum population size that is adequate for the long-term survival of wildlife populations? This paper presents three case studies in which policy makers decided how much was enough for protecting freshwater salmonid habitats. The case …

Scripps's Murrelet At San Miguel Island, California: Status Of A Small Population At The Northwest Limit Of The Breeding Range, Darrell L. Whitworth, Harry R. Carter

Western North American Naturalist

San Miguel Island (SMI) and its adjacent islets, Prince Island and Castle Rock, support a small population of Scripps’s Murrelets (Synthliboramphus scrippsi) at the northwest limit of their breeding range. In 1994–1996, 2004, 2007, and 2015, we conducted at-sea surveys and nest searches to determine the breeding distribution and population size of the Scripps’s Murrelet at the SMI group. During at-sea vocal surveys in 1994–1996, murrelet calls were heard at 4 stations around Prince Island (43–167 calls), 2 stations off Castle Rock (6 calls and 80 calls), and 4 stations off northeast SMI (5–123 calls), but none were …

Mitochondrial Fusion And Bid-Mediated Mitochondrial Apoptosis Are Perturbed By Alcohol With Distinct Dependence On Its Metabolism, Shamim Naghdi, William S. Slovinsky, Muniswamy Madesh, Emanual Rubin, György Hajnóczky

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell’s fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial permeability transition pore opening to promote cell death. EtOH-induced tissue injury is primarily attributed to its toxic metabolic products but alcoholism also impairs tissues that poorly metabolize EtOH. We embarked on studies to determine the respective roles of EtOH and its metabolites in mitochondrial fusion and tBid-induced mitochondrial apoptosis. We used HepG2 cells that do not metabolize EtOH and its engineered clone that expresses EtOH-metabolizing Cytochrome P450 E2 and alcohol …

Hyperphosphorylation Of Tau Associates With Changes In Its Function Beyond Microtubule Stability, Alejandra D. Alonso, Leah S. Cohen, Christopher Corbo, Viktoriya Morozova, Abdeslem Elldrissi, Greg R. Phillips, Frida E. Kleiman

Publications and Research

Tau is a neuronal microtubule associated protein whose main biological functions are to promote microtubule self-assembly by tubulin and to stabilize those already formed. Tau also plays an important role as an axonal microtubule protein. Tau is an amazing protein that plays a key role in cognitive processes, however, deposits of abnormal forms of tau are associated with several neurodegenerative diseases, including Alzheimer disease (AD), the most prevalent, and Chronic Traumatic Encephalopathy (CTE) and Traumatic Brain Injury (TBI), the most recently associated to abnormal tau. Tau post-translational modifications (PTMs) are responsible for its gain of toxic function. Alonso et al. …

Marsalis V. State Appellant's Brief Dckt. 45583

Not Reported

No abstract provided.

The Prospector, October 9, 2018, Utep Student Publications

The Prospector

Headline: UTEP Pharmacy Set to Close

Volume 116, Number 4 - Tuesday, October 9, 2018, Saint Mary's College Of California

The Collegian

No abstract provided.

College Of Education News, College Of Education, Georgia Southern University

College of Education: News & Publications (2003-2023)

• College of Education alum receives national recognition for administration role

• STEMFest returns with a bang, slime and even an alpaca

Westernmost Record Of The Diamondback Puffer, Lagocephalus Guentheri (Tetraodontiformes: Tetraodontidae) In The Mediterranean Sea: First Record From Greek Waters, P Kleitou, I Giovos, F Tiralongo, N Doumpas, G Bernardi

School of Biological and Marine Sciences

On 5th November 2017, a puffer fish specimen was caught in the Aegean Sea. Morphological and molecular analysis identified it as Lagocephalus guentheri. This first record from Greek waters represents the westernmost observation of the species in the Mediterranean Sea. The expansion and establishment of pufferfish species in the basin are discussed, with particular emphasis on the importance of the additional use of molecular analysis for increasing the efficiency in understanding species spread and dynamics.

Resilience, Resistance, And Reclamation: Changing The Narrative Of Higher Education, Cobretti D. Williams

Journal of Critical Scholarship on Higher Education and Student Affairs

At every turn and post on social media, we encounter images and reminders of the tumultuous sociopolitical climate of today. Scholars, educators, and activists are now being challenged to resist and reclaim our stories and identities in the face of extreme adversity. In order to honor the work of our community, we curated this special issue to challenge the status quo of higher education policies and practices used to divide us during the current Trump-era administration. Furthermore, this special issue speaks to the nuanced experiences that dismantle oppressive practices, illuminates the collective knowledge of marginalized voices, and hopefully, changes the …

Iima 2018 Proceedings, Emmnauel U. Opara, Jaymeen Shah, Abel Usoro, Louis Ngamassi

IIMA AND ICITED Annual Conference

Aplodinotus Grunniens - Freshwater Drum, Roger W. Barbour

Roger W. Barbour Slide Collection

Aplodinotus grunniens - Freshwater drum

A. Bifascia - Florida Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

A. bifascia - Florida Sand Darter

Aplodinotus Grunniens - Freshwater Drum, Roger W. Barbour

Roger W. Barbour Slide Collection

Aplodinotus grunniens - Freshwater drum

Ammocrypta Vivax - Scaly Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Ammocrypta vivax - Scaly Sand Darter

Ammocrypta Pellucida - Eastern Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Ammocrypta pellucida - Eastern Sand Darter

A. Meridiana - Southern Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

A. meridiana - Southern Sand Darter

Chologaster Cornuta - Swampfish, Roger W. Barbour

Roger W. Barbour Slide Collection

Chologaster cornuta - Swampfish

Carpiodes Carpio - River Carpsucker, Roger W. Barbour

Roger W. Barbour Slide Collection

Carpiodes carpio - River Carpsucker

Cichlasoma Cyanoguttatum - Rio Grande Cichlid, Roger W. Barbour

Roger W. Barbour Slide Collection

Cichlasoma cyanoguttatum - Rio Grande Cichlid

Campostoma C. Anomalum - Central Stoneroller, Roger W. Barbour

Roger W. Barbour Slide Collection

Campostoma c. anomalum - Central Stoneroller

Clinostomus Funduloides - Rosyside Dace, Roger W. Barbour

Roger W. Barbour Slide Collection

Clinostomus funduloides - Rosyside Dace

Chologaster Agassizi - Swampfish, Roger W. Barbour

Roger W. Barbour Slide Collection

Chologaster agassizi - Swampfish