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Trachemys Scripta Scripta, Roger W. Barbour

Roger W. Barbour Slide Collection

Trachemys scripta scripta

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Trachemys Scripta Troostii, Roger W. Barbour

Roger W. Barbour Slide Collection

Trachemys scripta troostii

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Trachemys Scripta Troostii, Roger W. Barbour

Roger W. Barbour Slide Collection

Trachemys scripta troostii

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Trachemys Stejnegeri Malonei, Roger W. Barbour

Roger W. Barbour Slide Collection

Trachemys stejnegeri malonei

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Pseudemys C. Concinna, Roger W. Barbour

Roger W. Barbour Slide Collection

Pseudemys c. concinna

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Pseudemys C. Hieroglyphica, Roger W. Barbour

Roger W. Barbour Slide Collection

Pseudemys c. hieroglyphica

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Aphredoderus Sayanus - Pirate Perch, Roger W. Barbour

Roger W. Barbour Slide Collection

Aphredoderus sayanus - Pirate Perch

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Discovering In Vivo Cytokine-Eqtl Interactions From A Lupus Clinical Trial, Emma E. Davenport, Tiffany Amariuta, Maria Gutierrez-Arcelus, Kamil Slowikowski, Harm Jan Westra, Yang Luo, Ciyue Shen, Deepak A. Rao, Ying Zhang, Stephen Pearson, David Von Schack, Jean S. Beebe, Nan Bing, Sally John, Michael S. Vincent, Baohong Zhang, Soumya Raychaudhuri

Cell and Molecular Biology Faculty Publications

Background: Cytokines are critical to human disease and are attractive therapeutic targets given their widespread influence on gene regulation and transcription. Defining the downstream regulatory mechanisms influenced by cytokines is central to defining drug and disease mechanisms. One promising strategy is to use interactions between expression quantitative trait loci (eQTLs) and cytokine levels to define target genes and mechanisms. Results: In a clinical trial for anti-IL-6 in patients with systemic lupus erythematosus, we measure interferon (IFN) status, anti-IL-6 drug exposure, and whole blood genome-wide gene expression at three time points. We show that repeat transcriptomic measurements increases the number of …

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