Digital Commons Network^™

Parents' Feelings And Perceptions Towards Their Child's Speech Or Language Disorder, Elizabeth Holley

Williams Honors College, Honors Research Projects

Throughout society, there remains a stigma in regards to a person’s speech and language. While the stereotype that a person with a speech or language disorder may have a lower quality of life shines light on the perceptions of mainstream society, there has been research that provides insight into parent’s feelings. The purpose of this project was to explore the research regarding parents’ feelings and perceptions towards their child’s speech or language disorder by conducting a literature review and a questionnaire that could be used as a measuring tool. The researchers used a questionnaire to focus on two main points: …

The Kinematics Of Salamander Underwater Walking On Smooth And Rough Substrate, Sophie Cressman

Williams Honors College, Honors Research Projects

The transition from aquatic to terrestrial locomotion was a landmark event in the evolutionary history of vertebrates. In order to better understand how early tetrapods were able to transition to land, salamanders have proven to be a useful animal model. With current research focusing heavily on the anatomy, physiology, and kinematics defining salamander terrestrial walking capabilities, this experiment was designed to extract information about the kinematics of salamander walking underwater. Underwater walking of salamanders was analyzed on smooth and rough substrates to provide more insight into the early vertebrate water-to-land transition. Average salamander stride duration, time in stance phase, time …

Development Of Entubulation Strategies For Treating Central Nervous System Injuries, Ivy Brosch

Williams Honors College, Honors Research Projects

According to the McKnight Brain Institute, at least 10,000 people annually in the USA suffer from a central nervous system (CNS) injury. These injuries can cause serve disabilities including paralysis. Due to the complexity of the spinal cord, it is common that potential CNS treatments are first applied to an optic nerve crush (ONC) model in rats. Two proposed treatments were employed; one where nerve growth factor (NGF) was immobilized to a chitosan substrate to stimulate axonal regeneration, and the other using pentadecafluorooctanoyl chloride modified methacrylamide chitosan (MAC(Ali15)F) hydrogel to enhance local oxygenation. The two different treatments were formed into …

A Systematic Review: Factors For Burnout And Compassion Fatigue In U.S. Nurses, Kaitlyn Marcum, Tabitha Rusnak, Mckenzie Koch

Williams Honors College, Honors Research Projects

Many nurses suffer from burnout and compassion fatigue. Compassion fatigue is “fatigue, emotional distress, or apathy resulting from the constant demands of caring for others or from constant appeals from charities” (Compassion Fatigue, n.d.). Burnout develops over a long period of time as a result of cumulative frustrations within a work environment (Sacco, Ciurzynski, Harvey, & Ingersoll, 2015). Burnout and compassion fatigue both result in physical and mental strain on the person experiencing it. Compassion fatigue and burnout in nurses are associated with decreased patient satisfaction and poorer outcomes with care (Potter et al., 2010). The goal of the systematic …

The Psychosocial Effects Of Hearing Loss On Adults, Holly Reed

Williams Honors College, Honors Research Projects

Adults with hearing loss report experiencing isolation, depression, a decreased satisfaction with their self - image and quality of life, cognitive problems and communication obstacles. These effects of a hearing loss can manifest in social situations, within the family and even at the workplace. How one copes with their hearing loss can affect how much of an impact their hearing loss has on their lives as well as what rehabilitative programs or assistive technology they may seek out. It is important to for audiologists to understand the psychosocial effects of hearing loss, how they affect the individual in the workplace …

Using A Coupled Bio-Economic Model To Find The Optimal Phosphorus Load In Lake Tainter, Wi, Mackenzie Jones

Williams Honors College, Honors Research Projects

In Dunn County, Wisconsin the lakes suffer from algae blooms due to excess phosphorus runoff. A coupled bio-economic model is studied with the intent of finding the optimal level of phosphorus that should be allowed into the lake depending on certain biologic and economic parameters. We model the algae and phosphorus concentration in the lake over time based off the phosphorus input. Community welfare is modeled by comparing the costs and benefits of phosphorus fertilizer. This model is proposed to find the phosphorus level that maximizes community welfare and then determine how certain environmental and social change initiatives will affect …

Physical Therapy And The Integration Of Dry Needling, Katie Montgomery

Williams Honors College, Honors Research Projects

This research paper analyzes how the field of Physical Therapy has grown and evolved in the United States over the last sixty years. It also explores the education process of becoming a therapist, the responsibilities it entails, and the different treatment interventions therapist can use by taking a deeper look at the integration of dry needling techniques into the field of Physical Therapy.

Dry needling is defined and different techniques being utilized in the field currently are explained. Also discussed are locations where physical therapists are legally allowed to perform dry needling in the United States, the certification process, precautions …

Multiple Antibodies Are Effective At Labeling S-Opsin Cones, Jenna Jamil

Williams Honors College, Honors Research Projects

Cones are a type of photoreceptor found in the retina that initiates visual processes. Cones can respond to different wavelengths of light and therefore allow for color vision. They are also responsible for high acuity and daylight vision (Ueno et al 2018). Immunohistochemistry is a technique that can be used to label and visualize specific types of cones in the mouse retina. A primary antibody is used to bind to a specific antigen, such as s-opsin in cones. A secondary antibody with a fluorescent marker then binds to the primary antibody to allow for amplification and visualization. Through effectively labeling …

Mutations In Rhodopsin Transmembrane Helix 5 And Dimerization Interface, Margaret Pinkevitch

Williams Honors College, Honors Research Projects

G protein coupled receptors (GPCRs) are membrane proteins with many functional roles. This family of receptors is expansive, with several subfamilies. Here, a member of subfamily A, rhodopsin (Rho) is studied. Mutations in rhodopsin have been linked to the disease retinitis pigmentosa (RP). Some of these mutations have been found to disrupt the dimerization/oligomerization of Rho at the TM4/TM5 proposed dimerization interface, causing pathogenesis of RP. In this study, two mutations of transmembrane helix 5 were investigated for changes in dimerization and stability, cell trafficking, and signaling. It was found that the V209M and F220C mutations did not result in …

An Exploration Of The Relationships Between Mindfulness And Obesity-Related Eating Behaviors, Jennifer Battles

Master's Theses and Doctoral Dissertations

Little research has explored the basic relationships between different components of mindfulness and eating behaviors associated with obesity even though mindfulness-based interventions (MBIs) have been widely utilized to treat eating behaviors. This study explored these relationships in order to inform more effective MBIs for obesity. Participants (N = 533) from a mixed community and undergraduate sample completed an online battery of assessments. All components of mindfulness were related to eating behaviors as would be expected, with the exception of trait mindful awareness. A series of multiple hierarchical regressions showed that mindful eating was a unique predictor of eating behaviors …

Mediating Effect Of Masculinity And Femininity On The Female Preponderance In Depression, Tara A. Baluck

Master's Theses and Doctoral Dissertations

Sex differences in major depressive disorder have been a consistent research finding, with women receiving a diagnosis nearly twice as often as men. A substantive amount of research has attempted to address this preponderance. One area that warrants further investigation is the role that gender, a social construct that, in part, refers to the degree to which one enacts traditionally masculine and/or feminine traits, may play in mediating the relationship between sex and depressive symptoms. Secondary data analysis was conducted using a previously collected sample of undergraduate students from a moderately sized Midwestern university. Measures include the Extended Personal Attributes …

Sexual Risk Behaviors Of African American Adolescent Females: The Role Of Cognitive And Religious Factors, Safiya George Dalmida, Natasha Aduloju-Ajijola, Dora L. Clayton-Jones, Tami Thomas, Ricardo J. Erazo Toscano, Rashunda Lewis, Terri Fleming, Shirley Taylor, Macie Lunyong

College of Nursing Faculty Research and Publications

Introduction: African American (AA) high school-age girls are more likely to have had sex before age 13 years and have higher rates of all sexually transmitted infections. Cognition and religion/spirituality are associated with adolescent sexuality, therefore, the purpose of this study was to identify cognitive and religious substrates of AA girls’ risky sexual behaviors. Method: A descriptive study was conducted with 65 AA girls aged 15 to 20 years using computerized questionnaires and cognitive function tasks. Results: Average age was 17.8 ± 1.9 years and average sexual initiation age was 15.5 ± 2.6 years. Overall, 57.6% reported a history of …

Feasibility And Pilot Testing Of A Mindfulness Intervention For Frail Older Adults And Individuals With Dementia, Christine R. Kovach, Crystal-Rae Waltons, Lisa Sattell, Kimberly Rosenau, Sandeep Gopalakrishnan

College of Nursing Faculty Research and Publications

Mindfulness interventions have been beneficial for healthy adults and individuals experiencing a stressful medical or mental health diagnosis. The purposes of the current study were to: (a) determine feasibility of mindfulness for older adults in long-term residential settings, and (b) examine differences in outcomes between a mindfulness and cognitive activity. The current study is the first mindfulness study to include individuals in moderate and severe stages of dementia, and included 36 individuals with a range of cognitive abilities. A crossover design was used, and the intervention was feasible for continued practice by individuals with cognitive impairment. Statistically significant short-term changes …

Socially Accountable Medical Education: An Innovative Approach At Florida International University Herbert Wertheim College Of Medicine, Fiu Herbert Wertheim College Of Medicine Affiliates

All Publications

PROBLEM:

Despite medical advances, health disparities persist, resulting in medicine's renewed emphasis on the social determinants of health and calls for reform in medical education.

APPROACH:

The Green Family Foundation Neighborhood Health Education Learning Program (NeighborhoodHELP) at Herbert Wertheim College of Medicine provides a platform for the school's community-focused mission. NeighborhoodHELP emphasizes social accountability and interprofessional education while providing evidence-based, patient- and household-centered care. NeighborhoodHELP is a required, longitudinal service-learning outreach program in which each medical student is assigned a household in a medically underserved community. Students, teamed with learners from other professional schools, provide social and clinical services to …

Sculpted From Clay, Shaped By Power: Feminine Narrative And Agency In Wonder Woman, Mikala Carpenter

Master's Theses and Doctoral Dissertations

By applying deconstructive and feminist theories to the Wonder Woman saga, this thesis develops a potential definition of feminine narrative in contrast to the normative and exclusionary patriarchal narrative that reigns supreme in popular culture and Western ideology. Though much of comics discourse functions on the assumption that superhero narratives are homogenous reflections of this ideological hero narrative, I posit that the Amazonian princess's resilience and iconicity stem from her own narrative's uniquely deconstructive nature: Where the patriarchal story would demand dominance, destruction, and violence, the feminine narrative that Diana models advocates for equality, nurturance, and emotional and rational communication. …

Salt Retention In Wetland Soils And Effects On Dissolved Organic Carbon Export, Kayla Marie Mcguire

Master's Theses and Doctoral Dissertations

Deicing salt runoff has negative effects on ecosystems. Wetland ecosystems can act as important filters for runoff pollution (e.g., nutrients), mitigating damage to plants and microbes. Wetlands are important sinks for nutrients and pollutants (e.g., road salt) and transformation spots for many nutrients including carbon. The interactions between deicing salt runoff and wetland soil carbon were explored by measuring chloride export and retention, dissolved organic carbon (DOC) export, and carbon quality using mesocosm experiments. Net retention of Cl- was highest in soils receiving high salt treatments (5.0 g/L NaCl), although percent retention of Cl- was greater in soils receiving moderate …

Fear And (Non) Fiction: Agrarian Anxiety In “The Colour Out Of Space”, Antonio Barroso

Master's Theses and Doctoral Dissertations

This literary and sociological study examines H.P. Lovecraft’s “The Colour Out of Space” alongside New England agricultural societies in the late nineteenth and early twentieth centuries as their members faced socio-political change. Anxieties expressed in the short story reflect fears of communities facing erasure at the hands of a reservoir project. Patterns of historical American rural communities facing destruction in the name of progress as well as modern communities facing similar threats show the endurance of Lovecraft’s specific brand of fear.

Structural Evidence Of A Major Conformational Change Triggered By Substrate Binding In Dape Enzymes: Impact On The Catalytic Mechanism, Boguslaw P. Nocek, Cory Reidl, Anna Starus, Tahirah Heath, David L. Bienvenue, Jerzy Osipiuk, Robert Jedrzejczak, Andzrej Joachimiak, Daniel P. Becker, Richard C. Holz

Chemistry Faculty Research and Publications

The X-ray crystal structure of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae (HiDapE) bound by the products of hydrolysis, succinic acid and l,l-DAP, was determined at 1.95 Å. Surprisingly, the structure bound to the products revealed that HiDapE undergoes a significant conformational change in which the catalytic domain rotates ∼50° and shifts ∼10.1 Å (as measured at the position of the Zn atoms) relative to the dimerization domain. This heretofore unobserved closed conformation revealed significant movements within the catalytic domain compared to that of wild-type HiDapE, which results in effectively closing off access to …

Human P450 Cyp17a1: Control Of Substrate Preference By Asparagine 202, Michael C. Gregory, Piotr J. Mak, Yogan Khatri, James R. Kincaid, Stephen G. Sligar

Chemistry Faculty Research and Publications

CYP17A1 is a key steroidogenic enzyme known to conduct several distinct chemical transformations on multiple substrates. In its hydroxylase activity, this enzyme adds a hydroxyl group at the 17α position of both pregnenolone and progesterone at approximately equal rates. However, the subsequent 17,20 carbon–carbon scission reaction displays variable substrate specificity in the numerous CYP17A1 isozymes operating in vertebrates, manifesting as different K_d and k_cat values when presented with 17α-hydroxypregnenlone (OHPREG) versus 17α-hydroxyprogesterone (OHPROG). Here we show that the identity of the residue at position 202 in human CYP17A1, thought to form a hydrogen bond with the A-ring alcohol …

Layer-By-Layer Assembly Of Graphene Oxide On Thermosensitive Liposomes For Photo-Chemotherapy, Mohadeseh Hashemi, Meisam Omidi, Bharadwaj Muralidharan, Lobat Tayebi, Matthew J. Herpin, Mohammad Ali Mohagheghi, Javad Mohammadi, Hugh D.C. Smyth, Thomas E. Milner

School of Dentistry Faculty Research and Publications

Stimuli responsive polyelectrolyte nanoparticles have been developed for chemo-photothermal destruction of breast cancer cells. This novel system, called layer by layer Lipo-graph (LBL Lipo-graph), is composed of alternate layers of graphene oxide (GO) and graphene oxide conjugated poly (l-lysine) (GO-PLL) deposited on cationic liposomesencapsulating doxorubicin. Various concentrations of GO and GO-PLL were examined and the optimal LBL Lipo-graph was found to have a particle size of 267.9 ± 13 nm, zeta potentialof +43.9 ± 6.9 mV and encapsulation efficiency of 86.4 ± 4.7%. The morphology of LBL Lipo-graph was examined by cryogenic-transmission electron microscopy (Cryo-TEM), atomic …

The Efficacy Of Commercial Tooth Storage Media For Maintaining The Viability Of Human Periodontal Ligament Fibroblasts, W. Lee, Sheila E. Stover, Morteza Rasoulianboroujeni, K. Sherman, Farahnaz Fahimipour, E. Dashtimoghadam, C. Zito, Hossein E. Jazayeri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Aim

To evaluate Save‐A‐Tooth (SAT), EMT Toothsaver (EMT) and Hank's Balanced Salt Solution (HBSS) for their influence on the viability and proliferative capacity of human periodontal ligament fibroblasts (HPDLFs).

Methodology

Primary HPDLFs were seeded into 96‐well cell culture plates and exposed to SAT, EMT, HBSS and water (negative control) for 0.5, 1, 3, 6, 12 and 24 h at room temperature (22 °C). After each exposure time, cell viability was measured through quantifying adenosine triphosphate (ATP) using a luminescent dye. The proliferative capacity was also quantified using the PrestoBlue assay after 12 or 24 h storage in each medium. The …

Development Of Chitosan/Gelatin/Keratin Composite Containing Hydrocortisone Sodium Succinate As A Buccal Mucoadhesive Patch To Treat Desquamative Gingivitis, Zahra Davoudi, Mohammad Rabiee, Behzad Houshmand, Niloofar Eslahi, Kimia Khoshroo, Morteza Rasoulianboroujeni, Mohammadreza Tahriri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process. Mucoadhesive films increase the advantage of higher efficiency and drug localization in the affected region. In this research, mucoadhesive films, for the release of hydrocortisone sodium succinate, were prepared using different ratios of chitosan, gelatin and keratin. In the first step, chitosan and gelatin proportions were optimized after evaluating the mechanical properties, swelling capacity, water uptake, stability, and biodegradation of the films. Then, keratin was added at different percentages …

Survival Rates Of Stainless Steel Crowns And Multi-Surface Composite Restorations Placed By Dental Students In A Pediatric Clinic, Badia A. Zahdan, Aniko Szabo, Cesar D. Gonzalez, Elaye Okunseri, Christopher Okunseri

School of Dentistry Faculty Research and Publications

Purpose: This study examined survival rates of multi-surface composite restorations and stainless steel crowns (SSCs) placed by students in a pediatric dental clinic as well as the length of time it takes for restorations to be replaced with stainless steel crowns. Study design: Data from electronic dental records for all children with at least one 2-surface composite restorations or SSCs on a primary first or second molar from January 1, 2007 to September 30, 2015 were analyzed. The primary outcome was the time to a new restoration or SSC on the same tooth, with time to a crown as a …

Selection And Implementation Of Skill Acquisition Programs By Special Education Teachers And Staff For Students With Autism Spectrum Disorder, Tiffany Kodak, Tom Cariveau, Brittany A. Leblanc

Psychology Faculty Research and Publications

The present investigation examined special education teachers’ selection and use of teaching strategies for receptive identification training with children with autism spectrum disorder (ASD) in their classrooms. Teachers first responded to a survey in which they provided examples of receptive identification tasks taught in their classrooms, rated the efficacy of teaching strategies, described how they determined whether skills were mastered, listed any assessments they conducted to identify relevant prerequisite skills prior to receptive identification training, described how they selected teaching strategies for use in their classrooms, and listed their years of experience as a teacher and working with children with …

Resource Extraction And Infrastructure Threaten Forest Cover And Community Rights, Anthony J. Bebbington, Denise Humphreys Bebbington, Laura Aileen Sauls, John Rogan, Sumali Agrawal, César Gamboa, Aviva Imhof, Kimberly Johnson, Herman Rosa, Antoinette Royo, Tessa Toumbourou, Ricardo Verdum

Geography

Mineral and hydrocarbon extraction and infrastructure are increasingly significant drivers of forest loss, greenhouse gas emissions, and threats to the rights of forest communities in forested areas of Amazonia, Indonesia, and Mesoamerica. Projected investments in these sectors suggest that future threats to forests and rights are substantial, particularly because resource extraction and infrastructure reinforce each other and enable population movements and agricultural expansion further into the forest. In each region, governments have made framework policy commitments to national and cross-border infrastructure integration, increased energy production, and growth strategies based on further exploitation of natural resources. This reflects political settlements among …

Patterns And Drivers Of Recent Disturbances Across The Temperate Forest Biome, Andreas Sommerfeld, Cornelius Senf, Brian Buma, Anthony W. D’Amato, Tiphaine Després, Ignacio Díaz-Hormazábal, Shawn Fraver, Lee E. Frelich, Álvaro G. Gutiérrez, Sarah J. Hart, Brian J. Harvey, Hong S. He, Tomáš Hlásny, Andrés Holz, Thomas Kitzberger, Dominik Kulakowski, David Lindenmayer, Akira S. Mori, Jörg Müller, Juan Paritsis, George L.W. Perry, Scott L. Stephens, Miroslav Svoboda, Monica G. Turner, Thomas T. Veblen, Rupert Seidl

Geography

Increasing evidence indicates that forest disturbances are changing in response to global change, yet local variability in disturbance remains high. We quantified this considerable variability and analyzed whether recent disturbance episodes around the globe were consistently driven by climate, and if human influence modulates patterns of forest disturbance. We combined remote sensing data on recent (2001–2014) disturbances with in-depth local information for 50 protected landscapes and their surroundings across the temperate biome. Disturbance patterns are highly variable, and shaped by variation in disturbance agents and traits of prevailing tree species. However, high disturbance activity is consistently linked to warmer and …

Trends In Benthic Macrofaunal Populations, Seasonal Sea Ice Persistence, And Bottom Water Temperatures In The Bering Strait Region, Jacqueline M. Grebmeier, Karen E. Frey, Lee W. Cooper, Monika Kędra

Geography

Recent declines in sea ice extent and warming seawater temperatures in the Arctic have the potential to impact regional and pan-Arctic marine ecosystems. To investigate marine biological response to these key drivers and other environmental factors, we undertook a robust trend analysis of benthic macrofaunal populations and environmental drivers in the Bering Strait region. Our focus was on the waters of the northern Bering and southern Chukchi Seas, which are shallow (m) and seasonally productive, with strong pelagic-benthic coupling between water-column-derived organic matter and the seafloor. Studies indicate that both in situ production and advection of upstream phytodetritus support persistent …

(Un)Frozen Spaces: Exploring The Role Of Sea Ice In The Marine Socio-Legal Spaces Of The Bering And Beaufort Seas, Kristen L. Shake, Karen E. Frey, Deborah G. Martin, Philip E. Steinberg

Geography

Sea ice is a dynamic physical element of the greater Arctic marine system, one that has myriad connections to human systems on a variety of spatial and temporal scales. Changes to the spatial extent of sea ice simultaneously permits and endangers maritime operations, as well as impacts current debates over maritime boundaries, presenting an interesting challenge for international law. Sea ice is not a stationary object; it moves through time and space in response to the physical forces of wind, ocean currents, and heating. It has a tangible, material and substantive role in contestations over territory, resources and marine boundaries …

Sifting And Winnowing: Analysis Of Farmer Field Data For Soybean In The Us North-Central Region, Spyridon Mourtzinis, Juan I. Rattalino Edreira, Patricio Grassini, Adam C. Roth, Shaun N. Casteel, Ignacio A. Ciampitti, Hans J. Kandel, Peter M. Kyveryga, Mark A. Licht, Laura E. Lindsey, Daren S. Mueller, Emerson D. Nafziger, Seth L. Naeve, Jordan Stanley, Michael J. Staton, Shawn P. Conley

Department of Agronomy and Horticulture: Faculty Publications

Field trials are commonly used to estimate the effects of different factors on crop yields. In the present study, we followed an alternative approach to identify factors that explain field-to-field yield variation, which consisted of farmer survey data, a spatial framework, and multiple statistical procedures. This approach was used to identify management factors with strongest association with on-farm soybean yield variation in the US North Central (NC) region. Field survey data, including yield and management information, were collected over two crop growing seasons (2014 and 2015) from rainfed and irrigated soybean fields (total of 3568 field-year observations). Fields were grouped …

Genome-Wide Association Study For Identification And Validation Of Novel Snp Markers For Sr6 Stem Rust Resistance Gene In Bread Wheat, Amira M. I. Mourad, Ahmed Sallam, Vikas Belamkar, Stephen N. Wegulo, Robert Bowden, Yue Jin, Ezzat Mahdy, Bahy Bakheit, Atif A. El-Wafaa, Jesse Poland, Peter S. Baenziger

Department of Agronomy and Horticulture: Faculty Publications

Stem rust (caused by Puccinia graminis f. sp. tritici Erikss. & E. Henn.), is a major disease in wheat (Triticum aestivium L.). However, in recent years it occurs rarely in Nebraska due to weather and the effective selection and gene pyramiding of resistance genes. To understand the genetic basis of stem rust resistance in Nebraska winter wheat, we applied genome-wide association study (GWAS) on a set of 270 winter wheat genotypes (A-set). Genotyping was carried out using genotyping-by-sequencing and ~35,000 high-quality SNPs were identified. The tested genotypes were evaluated for their resistance to the common stem rust race in …