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Loss Of Dbc1 (Ccar2) Affects Tnfα-Induced Lipolysis And Glut4 Gene Expression In Murine Adipocytes, Ashley A. Able, Allison J. Richard, Jacqueline M. Stephens

Faculty Publications

© 2018 Society for Endocrinology Published by Bioscientifica Ltd. STAT5A (signal transducer and activator of transcription 5A) is a transcription factor that plays a role in adipocyte development and function. In this study, we report DBC1 (deleted in breast cancer 1 - also known as CCAR2) as a novel STAT5A-interacting protein. DBC1 has been primarily studied in tumor cells, but there is evidence that loss of this protein may promote metabolic health in mice. Currently, the functions of DBC1 in mature adipocytes are largely unknown. Using immunoprecipitation and immunoblotting techniques, we confirmed that there is an association between endogenous STAT5A …

Dna Methylomes Of Bovine Gametes And In Vivo Produced Preimplantation Embryos, Zongliang Jiang, Jianan Lin, Hong Dong, Xinbao Zheng, Sadie L. Marjani, Jingyue Duan, Zhengqing Ouyang, Jingbo Chen, Xiuchun Tian

Faculty Publications

© The Author(s) 2018. Published by Oxford University Press on behalf of Society for the Study of Reproduction. DNA methylation is an important epigenetic modification that undergoes dynamic changes in mammalian embryogenesis, during which both parental genomes are reprogrammed. Despite the many immunostaining studies that have assessed global methylation, the gene-specific DNA methylation patterns in bovine preimplantation embryos are unknown. Using reduced representation bisulfite sequencing, we determined genome-scale DNA methylation of bovine sperm and individual in vivo developed oocytes and preimplantation embryos. We show that (1) the major wave of genome-wide demethylation was completed by the 8-cell stage; (2) promoter …

The Pacific Sentinel, November 2018, Portland State University. Student Publications Board

The Pacific Sentinel

Editor: Jake Johnson

Articles in this issue include:

• Letter from the Editor
• All Taaj
• President Trump's Midnight "Nightcap" Sandwich
• Conversion Therapy: It's Time to Say No
• Disarming the Movement
• Examining Kavanaugh's Record
• Assassination Nation Asks
• Is It Really Just a Fantasy?
• Believe in Something, Don't Just Buy It
• Shock & Resistance in Puerto Rico
• Little Cow Pigeon
• Navy Vet Killed by Campus Police: #DisarmPSU Responds
• Palestinian Film Festival
• PSU Bored of Distrust
• Violent Mob Riots Show Support for Law and Order

Blood Transfusions In Preterm Infants: Changes On Perfusion Index And Intermittent Hypoxemia, Katrina T. Ibonia, Henrietta S. Bada, Philip M. Westgate, Enrique Gomez Pomar, Prasad Bhandary, Abhijit R. Patwardhan, Elie G. Abu Jawdeh

Pediatrics Faculty Publications

BACKGROUND

Red blood cell (RBC) transfusion decreases intermittent hypoxemia (IH) events beyond the first week of life. This benefit may be related to improved perfusion to the respiratory control network. Perfusion index (PI) is a perfusion measure provided by the pulse oximeter. We hypothesized that the benefit in IH after RBC transfusion is associated with an increase in PI. In addition, we assessed the value of PI and clinical measures in predicting the effect of RBC transfusion on IH.

STUDY DESIGN AND METHODS

We prospectively enrolled infants less than 30 weeks' gestation age. PI and oxygen saturation (SpO₂) …

Potential Use Of Dimocarpus Longan Seeds As A Flocculant In Landfill Leachate Treatment, Hamidi Abdul Aziz, Nor Aini Rahim, Siti Fatihah Ramli, Motasem Y.D. Alazaiza, Fatehah Mohd Omar, Yung-Tse Hung

Civil and Environmental Engineering Faculty Publications

Landfill leachate is a highly polluted and generated from water infiltration through solid waste produced domestically and industrially. In this study, a coagulation-flocculation process using a combination of Polyaluminium chloride (PACl) as a coagulant and Dimocarpus longan seed powder (LSP) as coagulant aid was used in treating landfill leachate. LSP has been tested as the main coagulant and as coagulant aid with PACl. As the main coagulant, the optimum dosage and pH for PACl were 5 g/L and 6, respectively, with removal efficiencies of 67.44%, 99.47%, and 98% for COD, SS, and color, respectively. For LSP as the main coagulant, …

Koh Treated Biochar: An Improved Material For The Removal Of Aqueous Contaminants, Cody Layne

Honors Theses

No abstract provided.

Glaze Exploration Via Nostalgic Locations, Robert A. Williams

Theses and Dissertations

In my art practice, collecting materials from personally significant locations has become a way to subtly reconnect people with places, nature, natural materials and processes. I produce well-made objects, with the end goal of allowing the viewer to feel and interact with traditional forms of beauty through craft, which is increasingly rare in our mechanized world. Raw materials are a direct link to nature and earth, a link which people in general can benefit from in essential ways. The processes of collecting and using naturally occurring materials to form links between objects and places resembles human relationships, and the connections …

私立嶺南大學蠶絲科發展史論, Chao Jiang, Quan Xia

嶺南學報 Lingnan Journal of Chinese Studies

蠶絲業在廣東近代經濟中具有舉足輕重的地位。20世紀二三十年代，私立嶺南大學蠶絲科根據廣東蠶絲業發展現狀，開展調查研究，展開蠶病治理與預防，改良蠶種培育與育蠶及桑種培育與栽桑技術，重視成果技術推廣，致力於廣東蠶絲業的發展，開展了一系列富有成效的活動。嶺南大學蠶絲科的發展既是美國改良廣東蠶絲的迫切需要的推動，又離不開廣東發展經濟的客觀要求，也是華人致力於嶺南大學“中國化”持續努力的結果；在促進蠶絲技術的改進，提高蠶絲品質的同時，增强了廣東蠶絲的市場競争力；也打破了傳統的蠶絲生産觀念，促進了蠶農對蠶絲應用技術的重視，在一定程度上促進了蠶絲業的發展。

An Ethanolic Extract Of Artemisia Scoparia Inhibits Lipolysis In Vivo And Has Antilipolytic Effects On Murine Adipocytes In Vitro, Anik Boudreau, Allison J. Richard, Jasmine A. Burrell, William T. King, Ruth Dunn, Jean Marc Schwarz, David M. Ribnicky, Jennifer Rood, J. Michael Salbaum, Jacqueline M. Stephens

Faculty Publications

© 2018, American Physiological Society. All rights reserved. An ethanolic extract of Artemisia scoparia (SCO) has metabolically favorable effects on adipocyte development and function in vitro and in vivo. In diet-induced obese mice, SCO supplementation significantly reduced fasting glucose and insulin levels. Given the importance of adipocyte lipolysis in metabolic health, we hypothesized that SCO modulates lipolysis in vitro and in vivo. Free fatty acids and glycerol were measured in the sera of mice fed a high-fat diet with or without SCO supplementation. In cultured 3T3-L1 adipocytes, the effects of SCO on lipolysis were assessed by measuring glycerol and free …

Maternal Encouragement Of Modest Behavior, Temperamental Shyness, And Anxious Withdrawal Linkages To Chinese American Children's Social Adjustment: A Moderated Mediation Analysis, Merve Balkaya, Charissa S.L. Cheah, Jing Yu, Craig H. Hart, Shuyan Sun

Faculty Publications

© 2018 John Wiley & Sons Ltd Past studies have revealed potential differences in the functional meaning and social evaluation of children's temperamental shyness between Chinese interdependence-oriented and North American independence-oriented cultural contexts. However, very little is known about shy Chinese American children's adjustment in Western school contexts and potential pathways underlying their adjustment. To address this gap in the literature, we examined the associations between Chinese American children's temperamental shyness and their social adjustment outcomes, including peer exclusion, prosocial behavior, and assertiveness/leadership skills. In addition, the mediating role of children's display of anxious-withdrawn behavior and the moderating role of …

Enhancer-Driven Alternative Promoters Of Imprinted Genes, Joomyeong Kim, Bambarendage P.U. Perera, Subash Ghimire

Faculty Publications

© 2018 Kim et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. In the current study, we characterized the expression and histone modification profiles of the alternative promoters found within imprinted Igf2r, Mest, Zac1, Peg3, Snrpn and non-imprinted Myc loci. In terms of expression pattern, the alternative promoters are highly tissue-specific, which is in a stark contrast to the ubiquitous expression of the corresponding main promoters. The alternative promoters are associated with the …

Performance Of Bt-Susceptible And -Heterozygous Genotypes Of Spodoptera Frugiperda (J.E. Smith) Possessing Single- Or Dual-Gene Resistance Alleles In Sequential Feedings Of Non-Bt And Cry1a.105/Cry2ab2 Maize Leaf Tissues, Yiwan Zhou, Ying Niu, Graham P. Head, Paula A. Price, Fangneng Huang

Faculty Publications

We simulated larval feeding behavior in seed blends of non-Bt and Bt maize to determine if seed blends create more favorable conditions for heterozygous-resistant insects over their Bt-susceptible counterparts. Survival, growth, development, and progeny production of four genotypes of the fall armyworm, Spodoptera frugiperda, Bt-susceptible (aabb), Cry1A.105 heterozygous resistant (Aabb), Cry2Ab2 heterozygous resistant (aaBb), and Cry1A.105/Cry2Ab2 heterozygous resistant (AaBb), were evaluated in eight feeding sequences (Seq 1–8) of non-Bt and MON 89034 Bt maize leaf tissue expressing the Cry1A.105 and Cry2Ab2 proteins. We report variation in the performance of the four genotypes across the feeding sequences and biological parameters measured. …

Stress Fluctuation, Crack Renucleation And Toughening In Layered Materials, C. J. Hsueh, L. Avellar, B. Bourdin, G. Ravichandran, K. Bhattacharya

Faculty Publications

It has been established that contrast in the elastic properties can lead to enhancement of fracture toughness in heterogeneous materials. Focussing on layered materials as a model system, we show that this enhancement is a result of two distinct phenomena – first, fluctuations in stress leading to regions where the stress intensity at the crack is considerably smaller than that of the macroscopically applied value; and second, the lack of stress intensity when a crack is at a compliant to stiff interface thereby requiring renucleation. Using theoretical, computational and experimental methods, we study two geometries – a layered material and …

Anticyclonic Eddy Edge Effects On Phytoplankton Communities And Particle Export In The Northern South China Sea, Lei Wang, Bangqin Huang, Edward A. Laws, Kuanbo Zhou, Xin Liu, Yuyuan Xie, Minhan Dai

Faculty Publications

No abstract provided.

Anticyclonic Eddy Edge Effects On Phytoplankton Communities And Particle Export In The Northern South China Sea, Lei Wang, Bangqin Huang, Edward A. Laws, Kuanbo Zhou, Xin Liu, Yuyuan Xie, Minhan Dai

Faculty Publications

No abstract provided.

...Of Cabbages And Kings, November 2018, Emeriti Society, University Of The Pacific

Emeriti Newsletter: "...Of Cabbages and Kings"

"...Of Cabbages and Kings" is the newsletter of the University of the Pacific Emeriti Society. Read more about the Emeriti Society of Pacific by clicking here.

Natural Cycle Versus Hormone Replacement Therapy Cycle In Frozen-Thawed Embryo Transfer, Ziya Kalem, Müberra Namlı Kalem, Batuhan Bakirarar, Erkin Kent, Timur Gurgan

Saudi Medical Journal

Objectives: To compare implantation rates, clinical pregnancy rates and live birth rates associated with natural and hormone replacement therapy (HRT) methods of endometrial preparation in frozen-thawed embryo transfer (FET) cycles. Methods: The results of 108 natural cycles and 224 HRT cycles of FET transfers performed in a private in vitro fertilization (IVF) center between June 2013 and August 2015 were retrospectively compared with respect to implantation rate, clinical pregnancy rate, and live birth rate. Results: A total of 144 embryos were transferred in 108 natural cycles and 357 embryos were transferred in 224 HRT cycles. No statistically significant differences were …

How To Build A Patient-Specific Hybrid Simulator For Orthopaedic Open Surgery: Benefits And Limits Of Mixed-Reality Using The Microsoft Hololens, Giuseppe Turini, Sara Condino, Paolo D. Parch, Rosanna M. Viglialoro, Nicola Piolanti, Marco Gesi, Mauro Ferrari, Vincenzo Ferrari

Computer Science Publications

Orthopaedic simulators are popular in innovative surgical training programs, where trainees gain procedural experience in a safe and controlled environment. Recent studies suggest that an ideal simulator should combine haptic, visual, and audio technology to create an immersive training environment. This article explores the potentialities of mixed-reality using the HoloLens to develop a hybrid training system for orthopaedic open surgery. Hip arthroplasty, one of the most common orthopaedic procedures, was chosen as a benchmark to evaluate the proposed system. Patient-specific anatomical 3D models were extracted from a patient computed tomography to implement the virtual content and to fabricate the physical …

Mortality And Flowering Of Great Basin Perennial Forbs After Experimental Burning: Implications For Wild Bees, Byron G. Love, James H. Cane

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The fates of native bee communities in the Great Basin sagebrush steppe are linked with the susceptibilities of their floral hosts to increasingly frequent wildfires. Postfire survival and subsequent flowering of six prevalent perennial wildflowers representing five families were quantified across a range of realistic fire severities created using a calibrated propane burn barrel. Five burn prescriptions of varying intensity and duration were applied to cultivated rows of basalt milkvetch (Astragalus filipes Torr. ex A. Gray), Blue Mountain prairie clover (Dalea ornata Eaton & J. Wright), sulphur-flower buckwheat (Eriogonum umbellatum Torr.), fernleaf biscuitroot (Lomatium dissectum Nutt.), blue penstemon (Penstemon cyaneus …

Triatomines: Trypanosomatids, Bacteria, And Viruses Potential Vectors?, Caroline Barreto Viera, Yanna Reis Praça, Kaio Luis Da Silva Bentes, Paula Beatriz Santiago, Sofia Marcelino Martins Silva, Gabriel Dos Santos Silva, Flávia Nader Motta, Izabela Marques Dourado Bastos, Jaime Martins De Santana, Carla Nunes De Araújo

Harold W. Manter Laboratory of Parasitology: Library Materials

Triatominae bugs are the vectors of Chagas disease, a major concern to public health especially in Latin America, where vector-borne Chagas disease has undergone resurgence due mainly to diminished triatomine control in many endemic municipalities. Although the majority of Triatominae species occurs in the Americas, species belonging to the genus Linshcosteus occur in India, and species belonging to the Triatoma rubrofasciata complex have been also identified in Africa, the Middle East, South-East Asia, and in the Western Pacific. Not all of Triatominae species have been found to be infected with Trypanosoma cruzi, but the possibility of establishing vector transmission …

The Sex Specific Effect Of Alcohol Consumption On Circulating Levels Of Ctrp3, Ashley R. Degroat, Christina K. Fleming, Samantha M. Dunlay, Kendra L. Hagood, Jonathan P. Moorman, Jonathan M. Peterson

ETSU Faculty Works

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The goal of this project was to establish the effect of alcohol consumption on the circulating levels of the adipose tissue derived protein C1q TNF Related Protein 3 (CTRP3). Adipose tissue secretes several adipokines, such as adiponectin and leptin, which exert a multitude of biological effects important for human health. However, adipose tissue is extremely sensitive to alcohol consumption, leading not only to disrupted fat storage, …

Characterization Of Tick Organic Anion Transporting Polypeptides (Oatps) Upon Bacterial And Viral Infections, Vikas Taank, Wenshou Zhou, Xuran Zhuang, John F. Anderson, Utpal Pal, Hameeda Sultana, Girish Neelakanta

Biological Sciences Faculty Publications

Background: Ixodes scapularis organic anion transporting polypeptides (OATPs) play important roles in tickrickettsial pathogen interactions. In this report, we characterized the role of these conserved molecules in ticks infected with either Lyme disease agent Borrelia burgdorferi or tick-borne Langat virus (LGTV), a pathogen closely related to tick-borne encephalitis virus (TBEV).

Results: Quantitative real-time polymerase chain reaction analysis revealed no significant changes in oatps gene expression upon infection with B. burgdorferi in unfed ticks. Synchronous infection of unfed nymphal ticks with LGTV in vitro revealed no significant changes in oatps gene expression. However, expression of specific oatps was significantly downregulated upon …

Wrongful Termi(Gay)Tion: A Comparative Analysis Of Employment Non-Discrimination Laws And The Lgbtq+ Workplace Protections In South Africa And The United States, Jared Ham

Cornell Law Review

Although the United States has made great strides toward equality for its LGBTQ+ citizens in recent years, South Africa has demonstrated far greater progress concerning equal protection and employment non-discrimination of its LGBTQ+ citizens. The South African Constitution, South African Constitutional Court cases, and laws passed by the South African Parliament all mandate that LGBTQ+ South Africans be treated equally to their heterosexual counterparts. Discrimination against LGBTQ+ South Africans is expressly forbidden— including in the employment context. The United States still lacks comprehensive federal employment non-discrimination laws or workplace protections for LGBTQ+ individuals. Extending Title VII—either via court decision or …

Stable Isotopes Reveal Opportunistic Foraging In A Spatiotemporally Heterogeneous Environment: Bird Assemblages In Mangrove Forests, Christina Buelow, April Reside, Ronald Baker, Marcus Sheaves

University Faculty and Staff Publications

Environmental heterogeneity can foster opportunistic foraging by mobile species, resulting in generalized resource and habitat use. Determining species’ food web roles is important to fully understand how ecosystems function, and stable isotopes can provide insight into the foraging ecology of bird assemblages. We investigated flexibility of food choice in mangrove bird assemblages of northeast Australia by determining whether species’ carbon and nitrogen isotopic values corresponded to foraging group classification described in the literature, such as groups of species that are omnivorous or insectivorous. Subsequently, we evaluated foraging group isotopic niche size, overlap, degree of individual specialization, and the probable proportions …

Multicellular Models Bridging Intracellular Signaling And Gene Transcription To Population Dynamics, Mohammad Aminul Islam, Satyaki Roy, Sajal K. Das, Dipak Barua

Computer Science Faculty Research & Creative Works

Cell signaling and gene transcription occur at faster time scales compared to cellular death, division, and evolution. Bridging these multiscale events in a model is computationally challenging. We introduce a framework for the systematic development of multiscale cell population models. Using message passing interface (MPI) parallelism, the framework creates a population model from a single-cell biochemical network model. It launches parallel simulations on a single-cell model and treats each stand-alone parallel process as a cell object. MPI mediates cell-to-cell and cell-to-environment communications in a server-client fashion. In the framework, model-specific higher level rules link the intracellular molecular events to cellular …

Daily Eastern News: November 01, 2018, Eastern Illinois University

November

No abstract provided.

13 Terrestrial Wetlands, Randall Kolka, Carl T Trettin

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

The objective of this chapter is to characterize the distribution of carbon stocks and fluxes in terrestrial wetlands within North America. The approach was to synthesize available literature from field measurements with analyses of resource inventory data to estimate wetland area, carbon stocks, and net ecosystem exchange (NEE) of carbon and methane (CH4) fluxes of terrestrial wetlands (see Appendices 13A, p. 547, and 13B, p. 557, for details1). Then, the findings employed from large-scale simulation studies provided additional context, with consideration given to the effects of disturbance regimes, restoration and creation of terrestrial wetlands, and the application of modeling tools …

Hiv Diagnosis Disclosure To Infected Children And Adolescents; Challenges Of Family Caregivers In The Central Region Of Ghana, Anna Hayfron-Benjamin, Dorcas Obiri-Yeboah, Stephen Ayisi-Addo, Peter Mate Siakwa, Sylvia Mupepi

Peer Reviewed Articles

Background

Disclosure of Human Immunodeficiency Virus (HIV) to infected older children and adolescents is essential for both personal health maintenance and HIV prevention within the larger population. Non-disclosure of HIV status has been identified as one of the potential barriers to optimum adherence especially in children and adolescents. Like many other countries in the SSA region, Ghana has significant number of children and adolescents infected by HIV, who have increased survival times, due to increased access to ART. However, both family caregivers and healthcare workers face an array of challenges with the disclosure process, including the timing, what information about …

Return To The Repressive: Re-Thinking Nature- Culture In Contemporary Feminist Theory, Deborah Goldgaber

Faculty Publications

In "History of Sexuality"(Vol I.) Foucault argued that repression is the wrong model of power, understanding it in exclusively negative terms, as external to the body it constrains and inhibits. Power may also be positive, productive, and constitutive of the body and its possibilities. Thus, an adequate account of the relation between cultural forces and the body, Foucault argues, must challenge the "repressive hypothesis"(RH). Contemporary feminist accounts of the body are structured by this same oppositional view of power Foucault assumed: to call on Rosi Braidotti's distinction, discursive (cultural) forces are either negative or repressive (potestas) or positive and empowering …

A Phenomenological Study Of The Experiences Of Middle School Teachers Working With Girls With High Functioning Autism, Kelly Parton Alves

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the experiences of middle school teachers who work with girls with high functioning autism or autism spectrum disorder (ASD) in eastern North Carolina. The theory guiding this study was disability theory, also known as critical disability theory (CDT). CDT, as described by Pothier and Devlin, Garland-Thomson, Glynne-Owen, Oliver, and Siebers was appropriate for this study as it sought to embrace individuals with disabilities rather than seeing disabilities as a deficiency to be cured. Because girls with ASD represent a seldom-studied group, this study may add to the literature by examining …