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The Ethosophy Of The Grizzly Man: Timothy Treadwell's Three Ethologies, Blake L. Ginsburg

Graduate Student Theses, Dissertations, & Professional Papers

This paper explores the ethical appropriateness and significance of Timothy Treadwell’s life among the bears and foxes of Alaska’s Katmai National Park and Preserve. In an attempt to reveal the formative and transformative aspects of Treadwell’s project, I rely upon an ethological framework developed by Matthew Calarco that moves beyond the narrow conception of ethology as a scientific practice aimed at systematic and rigorous documentation of the quantifiable aspects of animal behavior. While many people might be hesitant to conceive of Treadwell’s project as an ethological one, I hope to illuminate the ways in which his life among bears and …

Policy Analysis: Alaska Salmon Hatcheries, Jessica Eller

Graduate Student Theses, Dissertations, & Professional Papers

Using an adapted Ecological Risk Assessment (ERA) - Evaluation, this study analyzes policy regulating Alaska salmon hatcheries to evaluate its effectiveness at sustaining wild salmon runs.When Alaska became a state in 1959, its salmon industry was suffering from years of overfishing. Runs were at an all-time low, prompting constitutional drafters to mandate management of salmon via the sustained yield principle. The hatchery system that operates today and is responsible for a third of the commercial catch each year was put in place in the 1970s to help supplement depressed salmon runs. The effects of hatchery salmon on wild salmon populations …

40 Years On The International Flathead: An Assessment Of Transboundary River Governance, Jedd Sankar-Gorton

Graduate Student Theses, Dissertations, & Professional Papers

Global population growth, climate change, and industrialization, are putting extreme pressures on worldwide freshwater supplies (Cosens 2010). Of the global freshwater supplies, transboundary water sources play a crucial role in sustaining populations. Over 40% of humans on Earth rely on a transboundary river or lake for access to water, and 90% of the world’s population lives in countries that share bodies of water with at least one other country (UN 2008). Taken together, the motivations for improving governance of transboundary water systems have never been stronger. To meet the challenges associated with transboundary water governance, researchers working at multiple scales …

Neuromuscular Responses To Exhaustive Bouts Of Sprint Running In Non-Steady Speed Trials, Brandon C. Gruver, Matthew W. Bundle

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

Conflicting Hydraulic Effects Of Xylem Pit Structure Relate To The Growth-Longevity Tradeoff In A Conifer Species, Beth Roskilly

Graduate Student Theses, Dissertations, & Professional Papers

Consistent with a ubiquitous life history tradeoff, trees exhibit a negative relationship between growth and longevity among and within species. However, the mechanistic basis of this life history tradeoff is not well understood. In addition to tradeoffs among multiple traits based on resource allocation conflicts, life history tradeoffs may arise from tradeoffs based on single traits under opposing selection. While a myriad of factors likely contribute to the growth-longevity tradeoff in trees, we hypothesized that conflicting functional effects of xylem structural traits contribute to the growth-longevity tradeoff. We tested this hypothesis by examining the extent to which xylem morphological traits …

Understanding The Food Water Nexus: Characterizing The Impact Of Climatological Anomalies On Agrosystems, Patrick M. Wurster Jr.

Graduate Student Theses, Dissertations, & Professional Papers

Climate variability at global and regional scales is escalating with increased atmospheric carbon and is expected to magnify the intensity and duration of meteorological extremes, especially droughts. From the many environmental stresses that diminish crop production (e.g., soil salinity, frost, soil erosion) drought is one of the most prevalent. This study focuses on the sensitivity of three key crops produced in the northwestern United States to climatological anomalies, while controlling for attribution using anomalies in price. The study differs from similar studies in that we focus on variability in production which captures both yield (tonnes/ha) and cropping area (ha), as …

Directional Non-Covalent Interactions: Exploring The Nuances Of Halogen Bonds And Hydrogen Bonds In Solution And The Solid-State, Nicholas Blouin Wageling

Graduate Student Theses, Dissertations, & Professional Papers

Molecules interact in numerous ways. Halogen bonding is one of the most newly discovered and poorly understood non-covalent interactions. However, this attractive force may be a useful tool for chemists in various disciplines. The directional nature, and competitive strength of the interaction makes it a promising alternative to hydrogen bonding based molecules. Indeed, through crystal structures and solution phase anion titrations, this work has shown that a halogen bonding scaffold can outperform its hydrogen bonding analogue not only in overall interaction strength, but also in resistance to inactivation from polar solvents (an important feature in anion receptors, organocatalysts, and many …

Greening Of The Arctic: Plot-Scale Analysis Of Interactions Between Climate, Vegetation, And Permafrost At Toolik Lake, Alaska (1995 - 2017), Brianna Rick

Graduate Student Theses, Dissertations, & Professional Papers

Air temperatures across the Arctic have increased in recent decades, and through complex feedbacks, vegetation and permafrost (frozen ground) are actively responding as climate warming continues. This study investigates the trends and interactions of observed air, soil-surface temperature (SST), and active-layer thickness (ALT) at Toolik Lake on the Alaskan North Slope between 1995 and 2017, as well as vegetation change over time.

Time series between 1995 and 2017 at CALM site U12B, a 1 ha plot near Toolik Lake, reveal an increase (0.50 °C/decade) in mean summer (Jun-Aug) air temperatures and a decrease (­0.23 °C/decade) in mean summer SST. In …

Transfer Of Graphing Skills From Math To Chemistry, Brittany Danielle Busby

Graduate Student Theses, Dissertations, & Professional Papers

Most students begin their university studies with adequate mathematical skills to succeed in general chemistry. However, students have a demonstrated difficulty with the application of math in a chemistry context. The ability to apply skills to new contexts is known as transfer, and understanding and enhancing transfer of graphing skills into the context of chemistry is the primary purpose of this investigation. Graphing skills were selected as the area of emphasis because they provide a strong conceptual link between math and chemistry.

This is a two-phase, sequential, quasi-experimental, mixed-methods study. In the first phase of the study, the quantitative research …

Wonder Woman: A Case Study For Critical Media Literacy, Adriana N. Fehrs

Graduate Student Theses, Dissertations, & Professional Papers

To better grasp the messages Wonder Woman is sending to its audience, a Critical Media Literacy (CML), ideological, and feminist framework is used to examine whether, and if so how, Wonder Woman succumbs to stereotypes that are often portrayed in the media. These theories will be used in the ensuing project to build a curriculum aimed at high school students.The curriculum positions students to examine the hegemonic ideologies that are represented in pop culture, specifically Wonder Woman.

Effect Of Neuromodulation Of Short-Term Plasticity On Information Processing In Hippocampal Interneuron Synapses, Elham Bayat Mokhtari

Graduate Student Theses, Dissertations, & Professional Papers

Neurons convey information about the complex dynamic environment in the form of signals. Computational neuroscience provides a theoretical foundation toward enhancing our understanding of nervous system. The aim of this dissertation is to present techniques to study the brain and how it processes information in particular neurons in hippocampus.

We begin with a brief review of the history of neuroscience and biological background of basic neurons. To appreciate the importance of information theory, familiarity with the information theoretic basics is required, these basics are presented in Chapter 2. In Chapter 3, we use information theory to estimate the amount of …

Toxicity Evaluation Of A Novel Magnetic Resonance Imaging Marker Cocl2-N-Acetylcysteine In Rats, Li Wang, Mihai Gagea, Karen S. Martirosyan, Mary Johansen, Timothy Madden, Lisa Norberg, Kirk S. Culotta, Steven J. Frank

Physics & Astronomy Faculty Publications

C4 (cobalt dichloride-N-acetylcysteine [1% CoCl 2 :2% NAC]) is a novel magnetic resonance imaging contrast marker that facilitates visualization of implanted radioactive seeds in cancer brachytherapy. We evaluated the toxicity of C4. Rats were assigned to control (0% CoCl 2 :NAC), low-dose (0.1% CoCl 2 :2% NAC), reference-dose (C4), and high-dose (10% CoCl 2 :2% NAC) groups. Agent was injected into the left quadriceps femoris muscle of the rats. Endpoints were organ and body weights, hematology, and serum chemistry and histopathologic changes of tissues at 48 hours and 28 and 63 days after dosing. Student's t tests were used. No …

Applications Of Low Field Magnetic Resonance Imaging, Muhammad Waqas

University of the Pacific Theses and Dissertations

Magnetic resonance imaging is a non-invasive imaging modality that is used to produce detailed images of soft tissues within the human body. Typically, MRI scanners used in the clinical setting are high field systems because they have a magnetic field strength greater than 1.5 Tesla. The high magnetic field offers the benefit of high spatial resolution and high SNR. However, low filed systems can also produce high resolution MR images with the added benefit of imaging stiffer samples. In this study, a low field 0.5 T MR system was used to image various samples to demonstrate the capability of the …

Scholarly Open Access Publishing: Growth Of Lis Open Access Journals Visible Through Directory Of Open Access Journals, Prerna Singh

Library Philosophy and Practice (e-journal)

Open access is an effective way for the dissemination of the scholarly publishing. Open access opens new vistas of access and dissemination of scholarly communication to wider readers. Library and Information Science field also witnessed the ever growing trends of open access and its growth in the form of Open Access Journals (OAJ), Open Access Repositories (OAR), Open Source Software (OSS), Open Educational Resources (OER) and MOOC’s. The present study highlights the position of LIS open access journals indexed in DOAJ. Directory of Open Access Journals (DOAJ) is an indexing service indexes high quality peer-reviewed journal of Science & technology, …

Researchers' Scientific Performance In Researchgate: The Case Of A Technology University, Farahnaz Naderbeigi, Alireza Isfandyari-Moghaddam

Library Philosophy and Practice (e-journal)

With the advancement of technology and changes made in the scientific communication model, changes have been made in scientific evaluation methods. New technologies offer indicators that measure all the actions and interactions of scientists in the digital environment and create new aspects of scientific communication. This work has some purposes; first, mapping profile of scientific activities of faculty members of Sharif University of Technology (SUT) in “ResearchGate” (RG), second, intend to test the correlation h-index between the RG and Web of Science (WoS) and Scopus and Google Scholar (GS). Third, investigate SUT faculty members’ top h cited research RG in …

Improving Glycemic Control In Adult With Type 2 Diabetes, Basirat Romoke Triplett

Walden Dissertations and Doctoral Studies

Ninety percent of people with diabetes have Type 2 diabetes mellitus (T2DM). T2DM is a complex disease that affects every organ in the body, which makes effective management of the disease imperative. The American Association of Clinical Endocrinologist (AACE) and American College of Endocrinology (ACE) strongly recommended early treatment initiation among the target population to delay disease progression and complications. The purpose of this evidence-based project was to examine the impact of using the T2DM management algorithm for effective management of adults with T2DM over a 3-month period. The shared experience decision-making model and the chronic care model were used …

Bimetallic Complexes: The Fundamental Aspects Of Metal-Metal Interactions, Ligand Sterics And Application, Michael Bernard Pastor

University of the Pacific Theses and Dissertations

Metal containing complexes have been used to catalyze various organic transformations for the past few decades. The success of several mononuclear catalysts led to transition metal catalysts used in pharmaceuticals, environmental, and industrial processes. While mononuclear complexes have been used extensively, bimetallic systems have received far less attention. Bimetallic or polynuclear sites are commonly found in metalloenzymes that perform elegant transformation in biological systems, underlying their significance. Inorganic chemists take inspiration from nature and design model bimetallic complexes to further study this cooperativity effect. A bimetallic platform offers many structural and functional differences such as the identity of the metal …

Peptide-Drug Conjugate For Her2-Targeted Drug Delivery, Yan Wang

University of the Pacific Theses and Dissertations

Recent strategies for anticancer drug design have been focused on utilizing antibody as a drug or targeted moiety for targeted drug delivery. Antibody−drug conjugates (ADCs) have become a promising new class of targeted therapeutic agents for treatment of cancer. ADCs are designed to preferentially direct a cytotoxic drug to a cell-surface antigen recognized by an antibody. However, there are some challenges in developing ADCs, such as limited solid tumor penetration, high manufacturing costs and antibody-drug stoichiometry. Smaller molecules such as peptides have been shown to specifically bind to cancer related targets. These peptides can be used to form peptide-drug conjugates …

Comparing Equivalence-Based Instruction With Lecture-Based Instruction To Teach College Students To Identify Logical Fallacies, Kelly Roughgarden

University of the Pacific Theses and Dissertations

Educators and practicing professionals in many fields emphasize the importance of critical thinking for effective decision-making. However, critical thinking skills are not usually directly taught in traditional educational settings. A subset of these skills, identifying logical fallacies, could be amenable to direct instruction using procedures that establish conditional discriminations, such as equivalence-based instruction (EBI). EBI procedures have been shown to be effective and efficient when teaching a variety of skills, including the identification of logical fallacies, when compared with no-instruction and self-instruction control groups. The purpose of this study is to compare the effectiveness of web-based EBI procedures to a …

Aphasia Couples Therapy: A Case Study Of Conversational Coaching For A Man With Conduction Aphasia, Adriana Joma

University of the Pacific Theses and Dissertations

The purpose of this study was to contribute to the understanding of the effects of aphasia couples therapy (ACT) in a person with conduction aphasia. ACT is a social therapeutic approach that involves facilitating conversations between the person with aphasia (PWA) and their spouse, or caregiver. The participants in this study involved one pair. The dependent variables included conveyance of main concepts, use of intentional gestures, reflections and summary statements per conversation. Miscellaneous measures were also counted and analyzed including the PWA’s frequency of paraphasias, fillers (e.g. um, uh), and disfluencies. Baseline sessions involved the PWA watching a video clip, …

Investigations On Cancer Cell Biological Effects Of Cdk8 Inhibitor Q-12, Zhixin Lu

University of the Pacific Theses and Dissertations

Over the past two decades, protein kinases have been intensively investigated as targets to treat neoplastic diseases. Many protein kinase inhibitors not only have therapeutic potential but are becoming invaluable reagents for the study of cell signaling.

We aspired to use our Cyclin-Dependent Kinase 8 inhibitor, Q-12, as a probe for biomarker discovery for CDK8 inhibitor sensitive tumor types. Q-12 shows potent inhibition of cell viability and induction of apoptosis process in some triple-negative breast cancer and colorectal cancer cell lines in vitro. Western blot results indicate that the reduction of STAT1 phosphorylation could be a robust indicator of CDK8 …

Issues Of Equity Among Team Members In Special Education: Voices Of Parents New To Special Education, Amanda R. Johnson

University of the Pacific Theses and Dissertations

The Individuals with Disabilities Education Act requires local education agencies to include parents as equal team members in the cultivation of their child’s individual education plan (IEP). Despite law, studies have shown that parents experience barriers to being included in the process. Barriers such as a lack of information, lack of understanding of the law, and feelings of unequal status or power as compared to school district team members have been noted. The aim of this study was to explore the perceptions, feelings, and understanding of the initial IEP process as experienced by parents new to the world of special …

West Meets East: An Exploration Of The Ways American University Development Officers Can Build Guanxi With Chinese Parents, Jinrui Zhang Mone

University of the Pacific Theses and Dissertations

Because philanthropic support from alumni and their families is an important source of revenue for American colleges and universities, identifying ways to connect with Chinese students and cultivate philanthropic support from their parents is an essential component of fundraising efforts. In this study, I explored how American university advancement officers could employ guanxi to cultivate relationships with Chinese parent donors in order to increase U.S. higher education philanthropy efforts. The concept of guanxi, an important aspect of building and sustaining relationships in China, served as the focus for understanding Chinese parents’ connections with their children’s American universities. I employed …

Design And In Vitro Characterization Of Lipids With A Ph-Sensitive Conformational Switch And Their Liposomes For Anticancer Drug Delivery, Shen Zhao

University of the Pacific Theses and Dissertations

The traditional anticancer drugs are distributed in vivo through systemic blood circulation with a very small portion reaching the tumor site. Targeted drug delivery systems are developed in efforts to concentrate the drug molecules in the tissue of interest while reducing the drug distribution to healthy tissues to reduce the side effects. Liposomes are colloidal systems composed of amphiphilic molecules that assemble into vesicle structures in aqueous media. They are common carriers for targeted drug delivery with the advantages of low toxicity, low immunogenicity and the ability of encapsulating both lipophilic and hydrophilic drugs.

Prior research indicated the advantages of …

Characterization Of Membrane Associated Mucins In Ocular Surface Disease, Anna Ablamowicz

All ETDs from UAB

Mucins on the ocular surface are found in the tear film and are attached to corneal and conjunctival epithelial cells on the eye. The bulbar conjunctiva of the ocular surface can be divided into four anatomical regions: temporal, superior, nasal, and inferior. The palpebral conjunctiva is the epithelial layer of the inner surfaces of the upper and lower eyelids. In the tears, mucins provide lubrication of the ocular surface through formation of a hydrophilic gel. The primary mucin in the tear film is MUC5AC which is secreted by goblet cells that are located in varying densities within the bulbar conjunctiva. …

Parental Decision-Making In Use Of Complementary And Alternative Medicine, Meka B. Astin

All ETDs from UAB

One health care trend is the growing public interest in, and use of, complementary and alternative medicine (CAM). Research in the United States suggests that significant numbers of children are involved in various forms of alternative medicine. The purpose of this dissertation is to assess the predictors of parental decision-making of CAM use for their child using five categories of CAM therapies: alternative medical systems, biologically- based, mind-body, manipulative, and a separate and distinct category to include all CAM medical systems. Andersen’s health care Utilization Model (HUM), which holds that health service use is a function of predisposing, enabling, needs …

A Study To Examine The Relationship Between Hospital Mergers And Patient Experience, Timothy William Attebery

All ETDs from UAB

Since 2009, the United States has experienced another wave of hospital mergers. Consequently, health systems are getting larger and increasing their market concentration. How patients benefit from hospital consolidation remains an open issue for policy-makers, economists, health care executives, community leaders, politicians, government agencies, and others. One measure of healthcare consolidation’s impact, and its potential benefit/detriment, is how mergers affect patient experience, which, since 2007, has been measured by the standardized HCAHPS instrument. Hundreds of studies conducted over the past 50 years have found mergers trigger an internal, socially-disruptive effect in the first 12 to 24 months following the event …

Translucent Voices: Creating Sound Pedagogy And Safe Spaces For Transgender Singers In The Choral Rehearsal, Gerald Dorsey Gurss

Theses and Dissertations

While transgender rights and issues are gaining an increasing amount of attention in both pop culture and, to some extent, in the education sector, little information is available for the choral conductor that provides pedagogical tools for transitioning voices. This document provides conductor-educators with both a brief look at the transgender experience and also tools to create safe learning environments, from gender-inclusive language to vocal exercises to encourage healthy vocal transitions in transgender singers

Twenty-first century choruses are not the first institutions in the realm of Western art music that have faced visual, aural, and enigmatic conceptualizations of gender and …

Resilience, Glenda Militano

College of Graduate Studies: Theses & Dissertations

ABSTRACT

My objective for creating this body of work is to explore the complexity and beauty of the human brain. What inspired these works is my research on cognitive psychology and neuroscience. Cognitive psychology involves the study of internal mental processes, while neuroscience deals with nerves and nervous tissue that relate to behavior and learning. Neuroscience is where psychology meets biology. The series of paintings in Resilience, were created with the intent to connect these two fields of study, while charting my exploration and discoveries found linked with science and psychology. The brain and its components are portrayed in …

Quantifying Genetic Responses Of Plants To Drought Stress With A Comparative Transcriptome Approach, Jessica K. Devitt

College of Graduate Studies: Theses & Dissertations

Mentzelia section Bartonia (Loasaceae) commonly occurs in some of the hottest and driest places in North America, but we poorly understand the mechanisms that allow them to tolerate such extreme environments. Morphological and physiological adaptations are well studied in model organisms. The underlying genetic responses to drought stress in non-model organisms like Mentzelia is unknown. To better understand and identify differences and similarities in genetic responses to drought stress between species existing in different habitats with differing water availability, three species from the genus Mentzelia were compared. Species of section Bartonia occur across an environmental gradient, from temperate to arid …