Digital Commons Network^™

2018 Annual Report, Dmacc

Annual Reports

No abstract provided.

Ninemile Sod Transplants And Willow Monitoring, Colton W. Kyro, Aeriel Lavoie, Casey Goff, Tanner Pedretti

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Not available.

Asbury Theological Seminary Academic Catalog : 2018-2019, Asbury Theological Seminary

Academic Catalogs

No abstract provided.

Lycophron’S Alexandra: “Restaging” The East-West Conflict, Akira V. Yatsuhashi

New England Classical Journal

This paper argues that Lycrophon’s Alexandra overwrites the model of Herodotus to condense the conflict between East and West and advocate for uniformly “Greek” cultural identity. As the idea of what it meant to be Greek or barbarian began to transform with the events of the early Hellenistic period, concurrent literary works like those of Lycrophon responded to cultural anxieties by redefining Hellenicity to unite displaced Greek-speaking peoples. Herodotus and Lycrophon both claim epistemological authority of their narratives, but unlike Herodotus, Lycrophon explores the individual motivations of historical actors and incorporates both poetic and prose traditions into his narrative. In …

Institutionalizing Society’S Commitment To Child Well-Being, Lynn D. Wardle

Southern Illinois University Law Journal

“Protecting children is a top priority” was a headline in an American newspaper recently.  The headline and accompanying commentary—written by a member of the Minnesota state legislature—expressed a sentiment that is widely supported in the United States of America and in most nations around the world.  Similarly, the director of a British child services agency recently declared: “We need to think about the child’s physical safety, social safety, emotional safety—their whole wellbeing both at home and in the school environment.  Again, the sentiment is nearly universal.  In principle, nearly everyone agrees that the well-being of children should be given top …

Health Inequalities In Jordan And Their Social Determinants, Hoda Rashad, S. Shawky

Faculty Books

No abstract provided.

Renaissance Revenge And The Age Of Interiority, Riley Meachem

English Honors Papers

No abstract provided.

Combat-Related Reproductive Trauma: Implications For Quality Of Life And The Reproductive Narrative, Laura S. Covington

Bryn Mawr College Dissertations and Theses

Little research exists on the experiences of a combat-related injury that impairs fertility. This dissertation is a qualitative exploration of the lived experiences of military members after a genitourinary (GU) injury. It addresses the biological, psychological, and social impact on quality of life during recovery and subsequent attitudes about family development and sexual functioning. Building on both the life course perspective and the reproductive story model, this dissertation reviews literature on military culture, GU injury, and infertility to give a context to further analyze the essences of the phenomenon (Elder & Giele, 2009; Jaffe & Diamond, 2011).

This study is …

Management And Follow-Up Of Patients With A Bronchial Neuroendocrine Tumor In The Last Twenty Years In Ireland: Expected Inconsistencies And Unexpected Discoveries, Asta Agasarova, Clare Harnett, Niall Mulligan, Muhammad Shakeel Majeed, Alberto Caimo, Gianluca Tamagno

Articles

Bronchial neuroendocrine tumors (NET) are classified into well-differentiated typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC). We retrospectively reviewed and analyzed the diagnostic and therapeutic aspects, follow-up data, and outcomes of all patients diagnosed with a bronchial NET from 1995 to 2015 at our institution. Patients with LCNEC or SCLC were excluded due to the biological and clinical differences from the other bronchial NET. The clinical, laboratory, imaging, treatment, and follow-up data were collected and analyzed keeping in mind the recently published international recommendations. Forty-six patients were included in the study. …

Clustered Networks Protect Cooperation Against Catastrophic Collapse, Gwen Spencer

Mathematics Sciences: Faculty Publications

Assuming a society of conditional cooperators (or moody conditional cooperators), this computational study proposes a new perspective on the structural advantage of social network clustering. Previous work focused on how clustered structure might encourage initial outbreaks of cooperation or defend against invasion by a few defectors. Instead, we explore the ability of a societal structure to retain cooperative norms in the face of widespread disturbances. Such disturbances may abstractly describe hardships like famine and economic recession, or the random spatial placement of a substantial numbers of pure defectors (or round-1 defectors) among a spatially-structured population of players in a laboratory …

Synergistic Effect Of Smac-Mimetic And Poly (I:C) On Apoptosis Of Cholangiocarcinoma Cells, Thanpisit Lomphithak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cholangiocarcinoma (CCA), a malignancy transformed from cholangiocytes in the bile ducts is more common in Asia and has the highest incidence rate in Thailand. CCA is an aggressive malignancy which has high mortality, high recurrence rate and poor prognosis due to late diagnosis and lack of effective treatment, therefore identification of novel therapeutic targets could lead to the development of more efficient therapy. CCA is associated with chronic inflammation that could upregulate Toll-like receptor 3 (TLR3) in CCA cells. TLR3 agonist, poly(I:C) has been reported to directly induce apoptosis in selected cancers and also activates anti-tumor immunity. However, in some …

Louisiana Agriculture Winter, 2018, Lsu Agcenter

Louisiana Agriculture

No abstract provided.

Rape Myths And Hookup Culture: An Exploratory Study Of U.S. College Students' Perceptions, Timothy T. Reling, Michael S. Barton, Sarah Anna Becker, Matthew A. Valasik

Faculty Publications

The present study provides the first known systematic examination of the association of hookup culture endorsement and rape myth acceptance. Multivariate regression analysis was conducted to test the primary hypothesis that hookup culture endorsement would be the primary predictor of rape myth acceptance levels among a sample of 422 U.S. college students. Findings indicated the existence of a complex relationship in which rape myth acceptance increases or decreases based upon the form of hookup culture endorsement examined. Beliefs that hookups are harmless and elevate social status increased rape myth acceptance, whereas beliefs that hookups express sexual freedom decreased rape myth …

Medical Implications Of Space Radiation Exposure Due To Low-Altitude Polar Orbits, Jeffery C. Chancellor, Serena M. Auñon-Chancellor, John Charles

Faculty Publications

INTRODUCTION: Space radiation research has progressed rapidly in recent years, but there remain large uncertainties in predicting and extrapolating biological responses to humans. Exposure to cosmic radiation and solar particle events (SPEs) may pose a critical health risk to future spaceflight crews and can have a serious impact on all biomedical aspects of space exploration. The relatively minimal shielding of the cancelled 1960s Manned Orbiting Laboratory (MOL) program's space vehicle and the high inclination polar orbits would have left the crew susceptible to high exposures of cosmic radiation and high dose-rate SPEs that are mostly unpredictable in frequency and intensity. …

Mitochondria Targeting Ir780-Based Nanogumbos For Enhanced Selective Toxicity Towards Cancer Cells, Mi Chen, Nimisha Bhattarai, Mingyan Cong, Rocío L. Pérez, Karen C. Mcdonough, Isiah M. Warner

Faculty Publications

© 2018 The Royal Society of Chemistry. Herein, a simple counter-ion variation strategy is proposed and demonstrated for design of an array of near infrared IR780-based nanoGUMBOS (nanomaterials from a Group of Uniform Materials Based on Organic Salts) to produce enhanced anticancer activity. These nanomaterials were synthesized by direct nanoengineering of IR780-based GUMBOS using a reprecipitation method, without addition of any other materials. Thus, these novel nanomaterials can serve as carrier-free nanodrugs, providing several distinct advantages over conventional chemotherapeutics. Examination of the size and stability of these nanoGUMBOS indicates formation of approximately 100 nm nanoparticles that are stable under biological …

Rice H2a.Z Negatively Regulates Genes Responsive To Nutrient Starvation But Promotes Expression Of Key Housekeeping Genes, Sara Zahraeifard, Maryam Foroozani, Aliasghar Sepehri, Dong Ha Oh, Guannan Wang, Venkata Mangu, Bin Chen, Niranjan Baisakh, Maheshi Dassanayake, Aaron P. Smith

Faculty Publications

© The Author(s) 2018. Published by Oxford University Press on behalf of the Society for Experimental Biology. The H2A.Z histone variant plays a role in the modulation of environmental responses, but the nature of the associated mechanisms remains enigmatic. We investigated global H2A.Z deposition and transcriptomic changes in rice (Oryza sativa) upon exposure to phosphate (Pi) deficiency and in response to RNAi knockdown of OsARP6, which encodes a key component of the H2A.Z exchange complex. Both Pi deficiency and OsARP6-knockdown resulted in similar, profound effects on global H2A.Z distribution. H2A.Z in the gene body of stress-responsive genes was negatively correlated …

Improved Enantioselectivity For Atenolol Employing Pivot Based Molecular Imprinting, Andreea Elena Bodoki, Bogdan Cezar Iacob, Laura Elena Gliga, Simona Luminita Oprean, David A. Spivak, Nicholas A. Gariano, Ede Bodoki

Faculty Publications

© 2018 by the authors. In the last few decades, molecular imprinting technology went through a spectacular evolution becoming a well-established tool for the synthesis of highly selective biomimetic molecular recognition platforms. Nevertheless, there is still room for advancement in the molecular imprinting of highly polar chiral compounds. The aim of the present work was to investigate the favorable kosmotropic effect of a ternary complex involving a polar chiral template (eutomer of atenolol) and a functional monomer, bridged by a central metal ion through well-defined, spatially directional coordinate bonds. The efficiency of the chiral molecular recognition was systematically assessed on …

A Narrative Analysis Examining Influential Factors Of A Minority Research And Training Program, Gretchen S. Burton, Maria Da Graça H. Vicente

Faculty Publications

© The Author(s) 2018. The implementation of minority research and training programs at the postsecondary level has risen to close the educational achievement gap and generate a highly skilled and diverse science workforce. Numerous studies identify interventions influencing positive outcomes among minority research and training participants achieving graduate degrees. However, many of these studies utilize quantitative methods. To capture student voices and rich descriptive experiences, this study utilized a multiple case study featuring a narrative approach. Cross-case analysis identified four factors influencing matriculation into advanced degree programs: belonging and inclusion, peer mentoring, confidence as a scientist, and family influence. Findings …

Polypeptoid Polymers: Synthesis, Characterization, And Properties, Brandon A. Chan, Sunting Xuan, Ang Li, Jessica M. Simpson, Garrett L. Sternhagen, Tianyi Yu, Omead A. Darvish, Naisheng Jiang, Donghui Zhang

Faculty Publications

© 2017 Wiley Periodicals, Inc. Polypeptoids, a class of peptidomimetic polymers, have emerged at the forefront of macromolecular and supramolecular science and engineering as the technological relevance of these polymers continues to be demonstrated. The chemical and structural diversity of polypeptoids have enabled access to and adjustment of a variety of physicochemical and biological properties (eg, solubility, charge characteristics, chain conformation, HLB, thermal processability, degradability, cytotoxicity and immunogenicity). These attributes have made this synthetic polymer platform a potential candidate for various biomedical and biotechnological applications. This review will provide an overview of recent development in synthetic methods to access polypeptoid …

Expression Of An 8r-Lipoxygenase From The Coral Plexaura Homomalla, Nathaniel C. Gilbert, David B. Neau, Marcia E. Newcomer

Faculty Publications

© 2018 Elsevier Inc. Methods are presented for the use of the coral 8R-lipoxygenase from the Caribbean sea whip coral Plexaura homomalla as a model enzyme for structural studies of animal lipoxygenases. The 8R-lipoxygenase is remarkably stable and can be stored at 4°C for 3 months with virtually no loss of activity. In addition, an engineered “pseudo wild-type” enzyme is soluble in the absence of detergents, which helps facilitate the preparation of enzyme:substrate complexes.

A Spatiotemporal Dna Endoploidy Map Of The Arabidopsis Root Reveals Roles For The Endocycle In Root Development And Stress Adaptation, Rahul Bhosale, Veronique Boudolf, Fabiola Cuevas, Ran Lu, Thomas Eekhout, Zhubing Hu, Gert Van Isterdael, Georgina M. Lambert, Fan Xu, Moritz K. Nowack, Richard S. Smith, Ilse Vercauteren, Riet De Rycke, Veronique Storme, Tom Beeckman, John C. Larkin, Anna Kremer, Herman Höfte, David W. Galbraith, Robert P. Kumpf, Steven Maere, Lieven De Veylder

Faculty Publications

© 2018 ASPB. Somatic polyploidy caused by endoreplication is observed in arthropods, molluscs, and vertebrates but is especially prominent in higher plants, where it has been postulated to be essential for cell growth and fate maintenance. However, a comprehensive understanding of the physiological significance of plant endopolyploidy has remained elusive. Here, we modeled and experimentally verified a high-resolution DNA endoploidy map of the developing Arabidopsis thaliana root, revealing a remarkable spatiotemporal control of DNA endoploidy levels across tissues. Fitting of a simplified model to publicly available data sets profiling root gene expression under various environmental stress conditions suggested that this …

Trpc5 Is Required For The No-Dependent Increase In Dendritic Ca 2+ And Gaba Release From Chick Retinal Amacrine Cells, J. Wesley Maddox, Nikka Khorsandi, Evanna Gleason

Faculty Publications

© 2018 American Physiological Society. All rights reserved. GABAergic signaling from amacrine cells (ACs) is a fundamental aspect of visual signal processing in the inner retina. We have previously shown that nitric oxide (NO) can elicit release of GABA independently from activation of voltage-gated Ca 2+ channels in cultured retinal ACs. This voltage-independent quantal GABA release relies on a Ca 2+ influx mechanism with pharmacological characteristics consistent with the involvement of the transient receptor potential canonical (TRPC) channels TRPC4 and/or TRPC5. To determine the identity of these channels, we evaluated the ability of NO to elevate dendritic Ca 2+ and …

Nkg2d Regulation Of Lung Pathology And Dendritic Cell Function Following Respiratory Syncytial Virus Infection, Huan Liu, Andrew R. Osterburg, Jennifer Flury, Shuo Huang, Francis X. Mccormack, Stephania A. Cormier, Michael T. Borchers

Faculty Publications

© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. Background. Respiratory syncytial virus (RSV) is a common cause of respiratory tract infection in vulnerable populations. Natural killer (NK) cells and dendritic cells (DC) are important for the effector functions of both cell types following infection. Methods. Wild-type and NKG2D-deficient mice were infected with RSV. Lung pathology was assessed by histology. Dendritic cell function and phenotype were evaluated by enzyme-linked immunosorbent assay and flow cytometry. The expression of NKG2D ligands on lung and lymph node DCs was measured by immunostaining and …

Intergenic And Intronic Dna Hypomethylated Regions As Putative Regulators Of Imprinted Domains, Arundhati Bakshi, Corey L. Bretz, Terri L. Cain, Joomyeong Kim

Faculty Publications

© 2018 2018 Future Medicine Ltd. Aim: To investigate the regulatory potential of intergenic/intronic hypomethylated regions (iHMRs) within imprinted domains. Materials & methods: Based on the preliminary results of the histone modification and conservation profiles, we conducted reporter assays on the Peg3 and H19 domain iHMRs. The in vitro results were confirmed by the in vivo deletion of Peg3-iHMR designed to test its function in the Peg3 imprinted domain. Results & conclusion: Initial bioinformatic analyses suggested that some iHMRs may be noncanonical enhancers for imprinted genes. Consistent with this, Peg3- and H19-iHMRs showed context-dependent promoter and enhancer activity. Further, deletion …

Reference Assembly And Annotation Of The Pyrenophora Teres F. Teres Isolate 0-1, Nathan A. Wyatt, Jonathan K. Richards, Robert S. Brueggeman, Timothy L. Friesen

Faculty Publications

Pyrenophora teres f. teres, the causal agent of net form net blotch (NFNB) of barley, is a destructive pathogen in barley-growing regions throughout the world. Typical yield losses due to NFNB range from 10 to 40%; however, complete loss has been observed on highly susceptible barley lines where environmental conditions favor the pathogen. Currently, genomic resources for this economically important pathogen are limited to a fragmented draft genome assembly and annotation, with limited RNA support of the P. teres f. teres isolate 0-1. This research presents an updated 0-1 reference assembly facilitated by long-read sequencing and scaffolding with the assistance …

Biology And Management Of The Eastern Lubber Grasshopper (Orthoptera: Acrididae), T. D. Schowalter

Faculty Publications

The eastern lubber grasshopper, Romalea microptera (Beauvois) (Orthoptera: Acrididae), is locally common in swamps, open woodlands, weedy fields, and ditches in the southeastern United States. This species displays bold color patterns that vary from primarily lighter yellows and oranges in eastern portions of its range (although the black form occurs throughout the range) to shiny black with red markings in western portions, exemplifying aposematic (warning) coloration. This grasshopper has a wide host range, with more than 100 known host plants, from which it can sequester or synthesize a variety of toxic chemicals. Lubber defenses are highly effective against vertebrate predators, …

Biology And Management Of Root-Feeding Beetles (Coleoptera: Curculionidae) In North American Conifer Forests And Plantations, T. D. Schowalter

Faculty Publications

Root-feeding beetles, including several species of Hylastes Erichson (Coleoptera: Curculionidae), Hylurgops LeConte (Coleoptera: Curculionidae), Hylobius Gemar (Coleoptera: Curculionidae), Pachylobius LeConte (Coleoptera: Curculionidae), Pissodes Germar (Coleoptera: Curculionidae), and Steremnius Schönherr (Coleoptera: Curculionidae), have emerged as serious problems in conifer plantations and forests in the United States and Canada in recent decades. Root-feeding beetles are particularly associated with stressed, diseased, or injured trees. Emerging adults kill seedlings by girdling them at the root collar and kill older trees, at least in the North and West, by transmitting fungal root pathogens in the genus Leptographium Lagerberg & Melin (Ophiostomatales: Ophiostomataceae). In the South …

Simulating The Effects Of Co2 Gas Influx On The Thermodynamic Conditions Inside A Marine Riser Filled With Oil Based Mud, Hassan Al Dawood

Honors Capstones

No abstract provided.

2018 Annual Report, Louisiana Rice Research Board, Lsu Agcenter

Louisiana Rice Research Board Annual Report

No abstract provided.

Reducing Cardiovascular Disparities Through Community-Engaged Implementation Research: A National Heart, Lung, And Blood Institute Workshop Report, George A. Mensah, Richard S. Cooper, Anna Maria Siega-Riz, Lisa A. Cooper, Justin D. Smith, C. Hendricks Brown, John M. Westfall, Elizabeth O. Ofili, Leshawndra N. Price, Sonia Arteaga, Melissa C. Green Parker, Cheryl R. Nelson, Bradley J. Newsome, Nicole Redmond, Rebecca A. Roper, Bettina M. Beech, Jada L. Brooks, Debra Furr-Holden, Samson Y. Gebreab, Wayne H. Giles, Regina Smith James, Tené T. Lewis, Ali H. Mokdad, Kari D. Moore, Joseph E. Ravenell, Al Richmond, Nancy E. Schoenberg, Mario Sims, Gopal K. Singh, Anne E. Sumner, Roberto P. Treviño, Karriem S. Watson, M. Larissa Avilés-Santa

Faculty Publications

Cardiovascular disparities remain pervasive in the United States. Unequal disease burden is evident among population groups based on sex, race, ethnicity, socioeconomic status, educational attainment, nativity, or geography. Despite the significant declines in cardiovascular disease mortality rates in all demographic groups during the last 50 years, large disparities remain by sex, race, ethnicity, and geography. Recent data from modeling studies, linked micromap plots, and small-Area analyses also demonstrate prominent variation in cardiovascular disease mortality rates across states and counties, with an especially high disease burden in the southeastern United States and Appalachia. Despite these continued disparities, few large-scale intervention studies …