Digital Commons Network^™

Computational Analysis Of Broad Complex Zinc-Finger Transcription Factors, Barbara Mascareno-Shaw

The Pegasus Review: UCF Undergraduate Research Journal

Studies of transcription factors have provided important contributions toward understanding the cell morphology and developmental regulation of fruit flies based on sequence analysis of amino acid substitutions. In this report we describe the construction of four protein-DNA models based on two experimentally determined X-ray crystal structures (2DRP and 1A1H) using computational simulations of Z1, Z2, Z3, and Z4 zinc-finger DNA binding proteins. Once these models were constructed, 3 mutants were generated for the Z1/Z3 proteins. We evaluated the construction of the models and mutants against the templates using molecular mechanics (MM3) calculations in an attempt to determine the effect of …

The Indiana Statesman, January 26, 2018, Indiana State University

Student Newspaper

Group Xpo Showcase new fitness classes at the SRC; Stop and Serve, simple step to giving back; ISU responds to racial messages on campus; Warmer weather is turning turtles on this South Florida beach female

Career Corner: Quidel Looking For Students For Lab Assistant Posts, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Hear Us Roar, January 26, 2018, Michael Shonrock

Michael Shonrock

Digital newsletter produced by the office of President Michael Shonrock.

Microtubule-Actin Crosslinking Factor 1 And Plakins As Therapeutic Drug Targets, Quincy A. Quick

Biology Faculty Research

Plakins are a family of seven cytoskeletal cross-linker proteins (microtubule-actin crosslinking factor 1 (MACF), bullous pemphigoid antigen (BPAG1) desmoplakin, envoplakin, periplakin, plectin, epiplakin) that network the three major filaments that comprise the cytoskeleton. Plakins have been found to be involved in disorders and diseases of the skin, heart, nervous system, and cancer that are attributed to autoimmune responses and genetic alterations of these macromolecules. Despite their role and involvement across a spectrum of several diseases, there are no current drugs or pharmacological agents that specifically target the members of this protein family. On the contrary, microtubules have traditionally been targeted …

Kruppel-Like Factor 4-Dependent Staufen1-Mediated Mrna Decay Regulates Cortical Neurogenesis, Byoung-San Moon, Jinlun Bai, Mingyang Cai, Chunming Liu, Jiandang Shi, Wange Lu

Molecular and Cellular Biochemistry Faculty Publications

Kruppel-like factor 4 (Klf4) is a zinc-finger-containing protein that plays a critical role in diverse cellular physiology. While most of these functions attribute to its role as a transcription factor, it is postulated that Klf4 may play a role other than transcriptional regulation. Here we demonstrate that Klf4 loss in neural progenitor cells (NPCs) leads to increased neurogenesis and reduced self-renewal in mice. In addition, Klf4 interacts with RNA-binding protein Staufen1 (Stau1) and RNA helicase Ddx5/17. They function together as a complex to maintain NPC self-renewal. We report that Klf4 promotes Stau1 recruitment to the 3′-untranslated region of neurogenesis-associated mRNAs, …

”It Tells All Of Our History!” The Boi-Bumbá Festival Of Manaus, Marnie K. Watson

College of Humanities and Public Affairs

This article examines the discourse on modernity and nostalgia in Manaus, the capital of the Brazilian state of Amazonas, with a focus on the boi-bumbá festival, a folkloric dramatic dance that tells the story of the death and resurrection of a rancher’s beloved bull. Although most of the population lives in urban areas and engages in wage labor, the region is still popularly imagined as a “place that time forgot”: a natural area largely free of modern human intervention. This paper discusses how the boi-bumbá of Amazonas rose to stratospheric popularity in the context of urbanization, industrialization, political change, and …

Rare Parthenogenic Reproduction In A Common Reef Coral, Porites Astreoides, Alicia A. Vollmer

HCNSO Student Theses and Dissertations

Multiple stressors have caused a decline in coral populations. Broadcast spawning corals once dominated the Florida Reef Tract (FRT), but since their decline, smaller brooding corals, soft corals, and macroalgae are replacing them. Brooding corals are more resilient to current threats in part because they are reproductive throughout much of the year and their larvae are competent to settle after release. Despite the ubiquity of brooders on Florida reefs, much of their reproductive strategy remains unknown. This study aimed to examine paternity as a function of colony size and density in Porites astreoides, a common brooding coral in the …

The Trichoptera Of Panama V. Descriptions Of New Species, New Country Records, And A Synonymy, Brian J. Armitage, Steven C. Harris

Insecta Mundi

The Río Chiriqui basin is one of 52 major watershed areas, or cuencas, in the Republic of Panama. It occurs in western Panama, discharges into the Pacific Ocean, and includes portions of Volcán Barú on its northern extent. The Río Caldera occupies the northernmost subbasin of this basin. Two of its tributaries, Que­brada Grande and Quebrada Jaramillo, occur in close proximity and on opposite sides, and have different recent geologic histories and current land use patterns. During the course of investigating the caddisfly fauna of these two drainages, three new species of the microcaddisfly genus Neotrichia Morton (Trichoptera: Hydroptilidae) were …

A New Genus, A New Species, New Combinations, And Notes On Synonymy And Nomenclature In American Desmiphorini (Coleoptera, Cerambycidae, Lamiinae), Antonio Santos-Silva, James E. Wappes

Insecta Mundi

An early, overlooked description of the genus Atelodesmis (Coleoptera, Cerambycidae, Lamiinae) is attributed to Chevrolat (in Duponchel and Chevrolat 1841), with A. mannerheimii Duponchel and Chevrolat, 1841 as its type species, and the genus redescribed. Atelodesmis Buquet, 1857, is a junior synonym and primary homonym of Atelodesmis Chevrolat. Atelodesmis hirticornis Buquet, 1857 and A. vestita Buquet, 1857 are synony­mized with A. mannerheimii. Fallaxdesmis is described as a new genus with Atelodesmis unicolor Buquet, 1857 as type species. Atelodesmis piperita Bates, 1855 is transferred to Eupogonius and newly recorded for the state of Oaxaca, Mexico. A new species for Mexico …

The Minutes Of The Marshall University Graduate Council Meeting, January 26, 2018, Marshall University Graduate Council

Graduate Council Minutes

No abstract provided.

Rice Nucleosome Patterns Undergo Remodeling Coincident With Stress-Induced Gene Expression, Qi Zhang, Dong Ha Oh, Sandra Feuer Ditusa, Mangu V. Ramanarao, Niranjan Baisakh, Maheshi Dassanayake, Aaron P. Smith

Faculty Publications

© 2018 The Author(s). Background: Formation of nucleosomes along eukaryotic DNA has an impact on transcription. Major transcriptional changes occur in response to low external phosphate (Pi) in plants, but the involvement of chromatin-level mechanisms in Pi starvation responses have not been investigated. Results: We mapped nucleosomes along with transcriptional changes after 24-h of Pi starvation in rice (Oryza sativa) by deep sequencing of micrococcal nuclease digested chromatin and ribosome-depleted RNA. We demonstrated that nucleosome patterns at rice genes were affected by both cis- and trans-determinants, including GC content and transcription. Also, categorizing rice genes by nucleosome patterns across the …

Jim Brown, Former Coach, Men's Basketball, Wright State University, Dan Abrahamowicz, Jim Brown

Wright State University Retirees Association Oral History Project

On January 26, 2018, Dan Abrahamowicz interviewed Jim Brown about his long tenure as assistant and interim head coach of Wright State University’s men’s basketball program . Brown discusses the program’s founding years, the 1983 Division II national championship, the transition to Division I, and the construction of the Nutter Center. The interview highlights his role in recruiting, program development, and the growth of Wright State athletics.

First Record Of The Non-Native Pacu, Piaractus Brachypomus, In Lago Petén-Itzá, Guatemala, Central America, Diego J. Elias, Susan F. Mochel, Prosanta Chakrabarty, Caleb D. Mcmahan

Occasional Papers of the Museum of Natural Science, Louisiana State University

We documented the first record of the non-native species Piaractus brachypomus (Characiformes: Serrasalmidae) in Lago Petén-Itzá, Petén, Guatemala. One brined specimen was donated by a local fisherman in San Benito, El Petén. The captured specimen was reportedly collected in the southern basin of the lake. We used the mitochondrial gene cytochrome oxidase I (COI) to validate identity of the specimen. We hypothesize that the local aquarium trade is the most likely source of introduction of the non-native Pacu in Lago Petén-Itzá.

Documentamos el primer registro de la especie no nativa Piaractus brachypomus (Characiformes: Serrasalmidae) en el lago Petén Itzá, Petén, …

Holocene Dynamics Of Temperate Rainforests In West-Central Patagonia, Virginia Iglesias, Simon G. Haberle, Andrés Holz, Cathy Whitlock

Geography Faculty Publications and Presentations

Analyses of long-term ecosystem dynamics offer insights into the conditions that have led to stability vs. rapid change in the past and the importance of disturbance in regulating community composition. In this study, we (1) used lithology, pollen, and charcoal data from Mallín Casanova (47°S) to reconstruct the wetland, vegetation, and fire history of west-central Patagonia; and (2) compared the records with independent paleoenvironmental and archeological information to assess the effects of past climate and human activity on ecosystem dynamics. Pollen data indicate that Nothofagus-Pilgerodendronforests were established by 9,000 cal yr BP. Although the biodiversity of the understory increased …

An Examination Of Factors That Affect The Utilization Of Mental Health Services By Adolescents, Nichole A. Murray

USF Tampa Graduate Theses and Dissertations

Mental disorders among adolescents are on the rise and are among the most common chronic conditions, constituting a national epidemic. Prevalence rates indicate that 20–40% of the adolescent population in the U.S. suffers from emotional or behavioral difficulties significant enough to lead to functional impairment. Further, estimates suggest that more than 20% of the adolescent population has a diagnosable mental disorder, which significantly impacts their functioning substantially at school, at home and in their communities. Despite national agendas to address the mental health needs of adolescents, studies suggest that approximately 50 percent of adolescents with mental health needs do not …

Optimal Wavelength Selection For Optical Spectroscopy Of Hemoglobin And Water Within A Simulated Light-Scattering Tissue, Mikael Marois, Stephen L. Jacques, Keith D. Paulsen

Dartmouth Scholarship

An algorithm that selects optimal wavelengths for spectral fitting of diffuse light reflectance spectra using a nonnegative least squares method is presented. Oxyhemoglobin, deoxyhemoglobin, and water are considered representative absorbers, but the approach is not constrained or limited by absorber selection provided native basis spectra are available. The method removes wavelengths iteratively from a scattering-modulated absorption matrix by maximizing the product of its singular values and offers considerable improvements over previously published wavelength selection schemes. Resulting wavelength selections are valid for a broad range of optical properties and yield lower RMS errors than other wavelength combinations. The method is easily …

Academic Affairs Committee Agenda & Packet, Wku Board Of Regents

Board of Regents Documents

Action items:

• Scientific Data Analytics Graduate Certificate
• Sabbatical Leave Requests
• Emeritus Appointment

Lncrna Gene Signatures For Prediction Of Breast Cancer Intrinsic Subtypes And Prognosis, Silu Zhang, Junqing Wang, Torumoy Ghoshal, Dawn Wilkins, Yin-Yuan Mo, Yixin Chen, Yunyun Zhou

Faculty and Student Publications (Open Access)

Background: Breast cancer is intrinsically heterogeneous and is commonly classified into four main subtypes associated with distinct biological features and clinical outcomes. However, currently available data resources and methods are limited in identifying molecular subtyping on protein-coding genes, and little is known about the roles of long non-coding RNAs (lncRNAs), which occupies 98% of the whole genome. lncRNAs may also play important roles in subgrouping cancer patients and are associated with clinical phenotypes. Methods: The purpose of this project was to identify lncRNA gene signatures that are associated with breast cancer subtypes and clinical outcomes. We identified lncRNA gene signatures …

Descripción De Dos Especies Nuevas Del Género Aleuropleurocelus Drews Y Sampson, 1956 (Hemiptera: Aleyrodidae) De México, Vicente Emilio Carapia-Ruiz, Oscar Ángel Sánchez-Flores, Oswaldo García-Martínez, Antonio Castillo-Gutiérrez

Insecta Mundi

Resumen. En este estudio se describen dos nuevas especies de hemípteros del género Aleuropleurocelus (He­miptera: Aleyrodidae): Aleuropleurocelus mexicanus Carapia y Sánchez sp. nov., encontrada en los estados de Coahuila, México, Puebla, Sonora, y Tlaxcala en hojas de Quercus agrifolia Née y Quercus sp., y Aleuropleurocelus anahuac Carapia y Sánchez sp. nov. encontrada en los estados de México, Morelos y Puebla en el envés de hojas de Quercus. Se proporcionan microfotografías de estructuras morfológicas de puparios y se discute la separación con otras especies ovales de Aleuropleurocelus.

Abstract. In this study two new hemipteran species of the genus …

Primer Registro De Raoiella Indica Hirst, 1924 (Acari: Tenuipalpidae) En Guatemala, José Francisco García Ochaeta

Insecta Mundi

Se registra por primera vez el ácaro rojo de las palmas, Raoiella indica Hirst (Acari: Tenuipalpidae), en Guatemala. Este ácaro invasivo se encontró en los departamentos de Petén e Izabal infestando palma de coco (Cocos nucifera), palma de Navidad (Adonidia merrillii) y palmera robeleni (Phoenix roebelenii).

The red palm mite, Raoiella indica Hirst (Acari: Tenuipalpidae), is recorded for the first time in Guatemala. This invasive mite was found in the departments of Petén and Izabal infesting coconut palm (Cocos nucifera Linnaeus), Christmas palm (Adonidia merrillii (Becc.)) and pygmy date palm (Phoenix roebelenii O’Brien).

Identification Of Individuals For Directorship Roles: Evaluation Of A University’S Succession Management, Nana Yaw Oppong, Nancy Oduro-Asabere

The Qualitative Report

Identification of potential individuals for leadership roles is a critical aspect of a succession management programme, as other aspects of the programme depend on an effective identification. This study evaluates how the University of Cape Coast (UCC) in Ghana identifies potential non-academic senior members for directorship roles. We collected qualitative data through in-depth interviewing of nine directors at the university. We analysed the data using constant comparison analysis by developing three themes, under each of which we presented similar categories of data. We found that the criteria for identification of potential directors include seniority; both internal and external sources; and …

Volume Cxxxv, Number 11, January 26, 2018, Lawrence University

The Lawrentian

No abstract provided.

The Justinian

The Justinian

No abstract provided.

Ardoinia Nom. Nov., A Replacement Name For The Genus Orghidania Ardoin, 1977 (Coleoptera: Tenebrionidae) Non Capuse, 1971, Huseyin Ozdikmen

The Great Lakes Entomologist

A replacement name Ardoinia is proposed for the genus Orghidania Ardoin, 1977 in the family Tenebrionidae.

First Record Of The Soybean Aphid, Aphis Glycines (Hemiptera: Sternorrhyncha: Aphididae) In Connecticut And Massachusetts, Claire E. Rutledge

The Great Lakes Entomologist

The soybean aphid, Aphis glycines Matsumara, was first found in the United States in Wisconsin in the summer of 2000. Since that time it has spread to 21 states, primarily in the upper Midwest and 3 Canadian provinces. The predicted range of soybean aphid includes all of New England, but it had not yet been reported from Connecticut and Massachusetts. I surveyed two sites in each state during the summer of 2004: Hamden, CT on 4 August, Cromwell, CT on 1 September, and Plainfield, MA and Conway, MA on 10 September. Soybean aphids were present at all four sites. This …

Evaluation Of Experimental Populations And Glandular-Haired Varieties Of Alfalfa For Alfalfa Blotch Leafminer (Diptera: Agromyzidae) Feeding Injury, R. C. Venette, W. D. Hutchison, E. C. Burkness, C. C. Sheaffer

The Great Lakes Entomologist

Following the spread of the alfalfa blotch leafminer, Agromyza frontella (Rondani) (Diptera: Agromyzidae), into Minnesota and Wisconsin U.S.A. during 1994-1997, three field trials were conducted in Minnesota to assess the potential for leafminer resistance among several sources of alfalfa (Medicago sativa), germplasm. In 1998, 86 entries were evaluated, most of which were experimental populations. In addition, six commercial varieties of alfalfa were evaluated. Of the six varieties, four had been bred for various levels of glandular-hair expression, specifically for resistance to the potato leafhopper, Empoasca fabae (Harris) (Homoptera: Cicadellidae). In two of three trials, we found no significant differences …

Effect Of Short Term Cold Storage On The Quality Of Trichogramma Brassicae, T. Cacoeciae, And T. Evanescens (Hymenoptera: Trichogrammatidae), N. Ozder, O. Saglam

The Great Lakes Entomologist

Trichogramma cacoeciae Marchall, T. brassicae Bezdenko and T. evanescens Westwood (Hymenoptera: Trichogrammatidae) could be useful in biological control programs of agricultural insect pests. The possibility of storing Trichogramma species at low temperatures and the effect of such storage on the quality of the parasitoids and their fecundity were studied. Trichogramma cacoeciae, T. brassicae and T. evanescens pupae were stored 1, 2, 3, and 4 weeks at 4 ± 1 °C in a refrigerator, 60-70% R.H. and full darkness. Parasitoid emergence was 98.80%, 99.33% and 99.60% for T. cacoeciae, T. brassicae and T. evanescens, respectively, after 1 week of storage. Storage …

The Justinian

The Justinian

No abstract provided.

Survey For Etomopathogenic Nematodes And Entomopathogenic Fungi In Alfalfa Snout Beetle, Otiorhynchus Ligustici (L.) (Coleoptera: Curculionidae), Infested Fields In Hungary And In New York State, Gabor Neumann, Elson J. Shields

The Great Lakes Entomologist

A survey for etomopathogenic nematodes and fungi in alfalfa snout beetle Otiorhynchus ligustici (L.) infested fields was conducted in Hungary, where this beetle is native, and in New York State, where the alfalfa snout beetle is an invasive species. Soil samples were collected in Hungary and in New York in alfalfa snout beetle infested alfalfa fields in spring 2002. Galleria mellonella (L.) larvae were used as bait insects. The entomopathogenic fungi Beauveria bassiana and Metarhizium anisopliae were found in Hungary and New York. The frequency of plots with entomopathogenic fungi was not significantly different between locations in Hungary and New …