Digital Commons Network^™

Dietary Inflammatory Index And Cardiovascular Risk And Mortality—A Meta-Analysis, Nitin Shivappa, Justyna Godos, James R. Hébert, Michael Wirth, Gabriele Piuri, Attilio Speciani, Giuseppe Grosso

Faculty Publications

Diet and chronic inflammation have been suggested to be risk factors in the development of cardiovascular disease (CVD) and related mortality. The possible link between the inflammatory potential of diet measured through the Dietary Inflammatory Index (DII^®) and CVD has been investigated in several populations across the world. The aim of this study was to conduct a meta-analysis on studies exploring this association. Data from 14 studies were eligible, of which two were case-control, eleven were cohort, and one was cross-sectional. Results from the random-effects meta-analysis showed a positive association between increasing DII, indicating a pro-inflammatory diet, and …

February 12, 2018: New Google Partnership, Visitor Parking Update, Seminar Podcast, Saint Mary's College Of California

SMC Bulletin 2013-2020

No abstract provided.

University Of Northern Iowa Faculty Senate Meeting Minutes, February 12, 2018, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting minutes from the Faculty Senate of the University of Northern Iowa.

A New Computationally Efficient Method For Spacing N Points On A Sphere, Jonathan Kogan

Rose-Hulman Undergraduate Mathematics Journal

The problem of equally spacing n points on a sphere is impossible in general, but there are methods that come close to spacing the points equally. The method introduced in this paper uses a spiral that was found using experimental evidence. The resulting spacings are close to theoretical bounds, and the method is computationally efficient for large numbers of points. The method's accuracy ranges from 70% to 86% of the upper bound as n changes.

2018 Sdsu Data Science Symposium Program, South Dakota State University

SDSU Data Science Symposium

Table of Contents:

Letter from SDSU President
Letter from SDSU Department of Mathematics and Statistics Dept. Head
Sponsors
General Information
Keynote Speakers
Invited Speakers
Sunday Schedule
Workshop Information
Monday Schedule
Abstracts| Invited Speakers
Abstracts | Oral Presentations
Poster Presentation
Committee and Volunteers

Medical School Watercooler Newsletter - February 11, 2018, Lindsey Lyle

Watercooler Newsletter

This is the February 11, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA GHHS Members Participate in Solidarity Week, Highlight Compassionate Patient Care
• Multicenter Meta-Analysis Reveals Sepsis Patients can be Risk Stratified at the Time of Diagnosis Demonstrating Potential to Improve Critical Care Medicine on a Global Scale
• Internal Medicine to Host Multi-Departmental Grand Rounds on Feb. 22
• Summer Research Proposal Deadline Approaching
• USA Welcomes Dr. Preethi Marri
• USA Center for Healthy Communities Receives 2018 Health and Human Services Award

Descaling The Coffeemaker, Amy Mcvay Abbott

Erma Bombeck Writers' Workshop Blog

The retired life is resplendent with richness and meaning. It does not, however, free one from the tasks of ordinary life. I often must rise from my red velour chaise lounge, set the peppermint bonbons and glass of sherry aside, and attend to the mundane duties of the household.

Listeriolysin O Causes Enac Dysfunction In Human Airway Epithelial Cells., Guang Yang, Helena Pillich, Richard E. White, Istvan Czikora, Isabelle Pochic, Qiang Yue, Martina Hudel, Boris Gorshkov, Alexander Verin, Supriya Sridhar, Carlos M Isales, Douglas C Eaton, Jürg Hamacher, Trinad Chakraborty, Rudolf Lucas

PCOM Scholarly Works

Pulmonary permeability edema is characterized by reduced alveolar Na⁺ uptake capacity and capillary barrier dysfunction and is a potentially lethal complication of listeriosis. Apical Na⁺ uptake is mainly mediated by the epithelial sodium channel (ENaC) and initiates alveolar liquid clearance. Here we examine how listeriolysin O (LLO), the pore-forming toxin of Listeria monocytogenes, impairs the expression and activity of ENaC. To that purpose, we studied how sub-lytic concentrations of LLO affect negative and positive regulators of ENaC expression in the H441 airway epithelial cell line. LLO reduced expression of the crucial ENaC-α subunit in H441 cells within 2 h …

Direct Effects Of Warming Increase Woody Plant Abundance In A Subarctic Wetland, Lindsay G. Carlson, Karen H. Beard, Peter B. Adler

Wildland Resources Faculty Publications

Both the direct effects of warming on a species’ vital rates and indirect effects of warming caused by interactions with neighboring species can influence plant populations. Furthermore, herbivory mediates the effects of warming on plant community composition in many systems. Thus, determining the importance of direct and indirect effects of warming, while considering the role of herbivory, can help predict long-term plant community dynamics. We conducted a field experiment in the coastal wetlands of western Alaska to investigate how warming and herbivory influence the interactions and abundances of two common plant species, a sedge, Carex ramenskii, and a dwarf …

One-Stop Shop For The Research Lifecycle: Effects Of High-Impact Educational Practices On Library Spaces And Services In The Near- And Long-Term, Ngoc-Yen Tran

Faculty and Staff Publications

Higher education institutions of all sizes are focused on increasing retention and graduation rates and improving student engagement and learning through the usage of High-Impact Educational Practices (HIPs). This emphasis on HIPs have changed (and will continue to change) the spaces and services that university and college libraries offer, especially as libraries become the all-inclusive place in supporting the research lifecycle. Therefore, it is important for library staff to understand what HIPs are, how institutions are using them, and the impact that they already have and may have on libraries in the near- and long-term.

Living In The Avon Hills, Kyle Rauch

Living in the Avon Hills: A conference for the whole family (2014-)

A conference for the whole family.

Highly Metastatic K7m2 Cell Line: A Novel Murine Model Capable Of In Vivo Imaging Via Luciferase Vector Transfection, Brian T. Grisez, Justin J. Ray, Phillip A. Bostian, Justin E. Markel, Brock A. Lindsey

Clinical and Translational Science Institute

Osteosarcoma is rare and little improvement in survival rates has occurred in the last 25 years despite modern chemotherapeutic treatment. Bioluminescent cell lines for the modeling of osteosarcoma have shown success in tracking metastases in vivo, but commonly use adenoviral vectors to transfect the native cell line with bioluminescent reporters. The purpose of this study was to develop an orthotopic model for metastatic osteosarcoma capable of in vivo monitoring of metastatic and primary tumor burden in an immunocompetent mouse and compare that model to its wild type pathogenesis. K7M2 cells were transfected using a plasmid vector and were stable after …

Posthumanism: Anthropological Insights By Alan Smart And Josephine Smart, David Shaw

The Goose

Review of Alan Smart and Josephine Smart’s Posthumanism: Anthropological Insights.

The Microbial State: Global Thriving And The Body Politic By Stefanie R. Fishel, Dustin Purvis

The Goose

Review of Stefanie R. Fishel's The Microbial State: Global Thriving and the Body Politic.

Structural And Defensive Roles Of Angiosperm Leaf Venation Network Reticulation Ecross An Andes-Amazon Elevation Gradient, Benjamin Blonder, Norma Salinas, Lisa Patrick Bentley, Alexander Shenkin, Percy Chambi-Porroa, Yolvi Valdez Tejeira, Tatiana Erika Boza Espinoza, Gregory R. Goldsmith, Lucas Enrico, Roberta Martin, Gregory P. Asner, Sandra Diaz, Brian J. Enquist, Yadvinder Malhi

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

1.The network of minor veins of angiosperm leaves may include loops (reticulation). Variation in network architecture has been hypothesized to have hydraulic and also structural and defensive functions.

2.We measured venation network trait space in eight dimensions for 136 biomass-dominant angiosperm tree species along a 3,300 m elevation gradient in southeastern Peru. We then examined the relative importance of multiple ecological, and evolutionary predictors of reticulation.

3.Variation in minor venation network reticulation was constrained to three axes. These axes described branching vs. reconnecting veins, elongated vs. compact areoles, and high vs. low density veins. Variation in the first two axes …

Nanoscale Mapping Of In-Situ Micro Electro Mechanical Systems With Atomic Force Microscopy, Manuel Rivas

Master's Theses

Micro-electro-mechanical-systems (MEMS) are increasingly at our fingertips. To understand and thereby improve their performance, especially given their ever-decreasing sizes, it is crucial to measure their functionality in-situ. Atomic Force Microscopy (AFM) is well suited for such studies, allowing nanoscale lateral and vertical resolution of static displacements, as well as mapping of the dynamic response of these physically actuating microsystems. In this work, the vibration of a tuning fork based viscosity sensor is mapped and compared to model experiments in air, liquid, and a curing collagen gel. The switching response of a MEMS switch with nanosecond time-scale activation is also monitored …

Sikh Self-Sacrifice And Religious Representation During World War I, John Soboslai

Department of Religion Faculty Scholarship and Creative Works

This paper analyzes the ways Sikh constructions of sacrifice were created and employed to engender social change in the early twentieth century. Through an examination of letters written by Sikh soldiers serving in the British Indian Army during World War I and contemporary documents from within their global religious, legislative, and economic context, I argue that Sikhs mobilized conceptions of self-sacrifice in two distinct directions, both aiming at procuring greater political recognition and representation. Sikhs living outside the Indian subcontinent encouraged their fellows to rise up and throw off their colonial oppressors by recalling mythic moments of the past and …

Is There Anything Wrong With The Slogan “My Body My Choice” When It Comes To Abortion?, Jean Amost Cadet

Seminary Scholarship Symposium

Early evidence of induced abortion goes back to the 1500s BC. Aristotle’s work, later, described both chemical and mechanical methods to induce it, and ancient Rome also practiced it as a means of population control. Throughout history, there have also been primarily two opposing views regarding a woman’s right to terminate a pregnancy early: one, called pro-choice, which supports abortion for diverse reasons; and the other, pro-life, which opposes that practice, because to them, it is an attack on the most defenseless and helpless class of individuals, the unborn. The pro-choice group often refers to the slogan “My Body, My …

Just A Paper Moon: A Naturalist Reading Of A Streetcar Named Desire, Daniel Alexander Gonzalez

Theses and Dissertations

Tennessee Williams’ work A Streetcar Named Desire presents a complicated but rich text that does not fit in smoothly to any category of literature. I argue that while this complexity and difficulty of placement is true, the text is best seen through the lens of Naturalism due to the determined lives of the main characters, their attempts to escape these determined lives, and the tragic endings of these characters because of said attempts. This theory is explored in this thesis primarily through an analysis of the main characters of Blanche DuBois, Harold "Mitch" Mitchell, Stanley Kowalski, and Stella Kowalski. This …

The Determination Of The Biological And Biochemical Properties Of Four Purified Commercial Lectins From The Leguminosae, Karla M. Gonzalez

Theses and Dissertations

This study focused on the determination of the biological and biochemical properties of four purified commercial lectins from the Leguminosae. The anti-HIV reverse transcriptase activity of the lectins from Arachis hypogaea, Dolichos biflorus, Erythrina crista-galli, and Glycine max have not yet been reported. In addition, their antifungal, and antibacterial activities against Aspergillus niger, Candida albicans, Chaetomium globosum, Rhizopus stolonifer (+), Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Enterococcus faecalis are not yet known. All of these microorganisms have developed resistance to treatments in the last few years. Consequently, this study characterizes and compares the lectin activities of A. hypogaea, D. …

The Survival Of The Feminine Figure Through The Reconciliation Of Nature And Logos, Daniela Nunez

Theses and Dissertations

ABSTRACT The Survival of the Feminine Figure Through the Reconciliation of Nature and Logos (August 2017) Daniela Núñez Ochoa, B.A. English; B.A. Spanish, Texas A&M International University; Chair of Committee: Dr. Manuel Broncano This work focuses on analyzing and questioning the role two feminine protagonists play in a phallogocentric social system depicted within two novels. The research will explore the narrative and outcome experienced by Doña Bárbara and Janie Crawford, from Rómulo Gallegos’ Doña Bárbara and Zora Neale Hurston’s Their Eyes Were Watching God, in a post-colonial twentieth-century American continent. Hélène Cixous’ concept of feminine writing, which roots from her …

Representing Diversity In The Dish: Using Patient-Derived In Vitro Models To Recreate The Heterogeneity Of Neurological Disease, Layla T. Ghaffari, Alexander Starr, Andrew T. Nelson, Rita Sattler

Translational Neuroscience

Neurological diseases, including dementias such as Alzheimer's disease (AD) and fronto-temporal dementia (FTD) and degenerative motor neuron diseases such as amyotrophic lateral sclerosis (ALS), are responsible for an increasing fraction of worldwide fatalities. Researching these heterogeneous diseases requires models that endogenously express the full array of genetic and epigenetic factors which may influence disease development in both familial and sporadic patients. Here, we discuss the two primary methods of developing patient-derived neurons and glia to model neurodegenerative disease: reprogramming somatic cells into induced pluripotent stem cells (iPSCs), which are differentiated into neurons or glial cells, or directly converting (DC) somatic …

Wastewater Exfiltration Sources In Pearson Creek, Springfield, Missouri, Marc R. Owen, Robert T. Pavlowsky, Grace F. Roman

OEWRI Technical Reports

No abstract provided.

Effect Of The Specific Carbohydrate Diet On The Microbiome Of A Primary Sclerosing Cholangitis And Ulcerative Colitis Patient, Alanna Dubrovsky, Christopher Kitts

Biological Sciences

A 20-year-old female was diagnosed with ulcerative colitis (UC) at age 14 and primary sclerosing cholangitis (PSC) at age 16. The PSC was successfully treated with high doses of oral vancomycin; however, the UC was more difficult to manage. After many drug treatments failed to treat the UC, the patient began following the specific carbohydrate diet (SCD). This report documents fecal microbiome changes resulting from following the SCD for two weeks. The DNA extracted from fecal samples was subjected to 16S rRNA gene sequencing to quantify bacterial species abundance. Not only were substantial changes in the fecal bacterial composition detectable …

Eculizumab Dosing In Infants, M Kobrzynski, B Wile, S S Huang, G Filler

Paediatrics Publications

Eculizumab is the therapy of choice for patients with atypical hemolytic uremic syndrome (aHUS). Dosing recommendations stem from two trials: one retrospective trial (19 children and 5 infants) and one prospective trial (22 patients and 5 infants). This case report highlights the need for more precise dosing recommendations in children, particularly in infants, and for smaller vials of the medication to facilitate more precise dosing. Such changes would ensure that adverse events are minimized and that the children with aHUS who are treated with eculizumab experience an optimal clinical response.

Is Genetic Use Restriction Technology (Gurt) A Viable Alternative To The Utility Patent For The Protection And Promotion Of Innovation In Genetically Engineered Agricultural Seeds?, Joseph Rosenblat

PhD Dissertations

Patent protected genetically engineered (GE) agricultural seeds allow farmers to increase the quality and yield of some of the worlds most important food crops. The ability of GE seed firms to use this technology to capture value and promote innovation may be compromised by patent regimes that are not designed to prevent the misappropriation of self-replicating, biologically-based inventions.

Unlike patents, genetic use restriction technology (GURT) provides a primarily self-contained technological method of intellectual property (IP) protection effective in weak IP environments. Currently, GURT is subject to an international commercialization moratorium because of concerns over potential negative economic, environmental, health and …

Ucc Minutes Feb 9, 2018, Undergraduate Curriculum Committee

Undergraduate Currirculum Committee Minutes

No abstract provided.

Weigand Reports Positive News For Box Turtle Population Bisected By Us 33 Bypass, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Representing Diversity In The Dish: Using Patient-Derived In Vitro Models To Recreate The Heterogeneity Of Neurological Disease, Layla T. Ghaffari, Alexander Starr, Andrew T. Nelson, Rita Sattler

Department of Neuroscience Faculty Papers

Neurological diseases, including dementias such as Alzheimer's disease (AD) and fronto-temporal dementia (FTD) and degenerative motor neuron diseases such as amyotrophic lateral sclerosis (ALS), are responsible for an increasing fraction of worldwide fatalities. Researching these heterogeneous diseases requires models that endogenously express the full array of genetic and epigenetic factors which may influence disease development in both familial and sporadic patients. Here, we discuss the two primary methods of developing patient-derived neurons and glia to model neurodegenerative disease: reprogramming somatic cells into induced pluripotent stem cells (iPSCs), which are differentiated into neurons or glial cells, or directly converting (DC) somatic …

Impact Of Protein Internal Dynamics, Process And Formulation Variables On Freeze-Dried Protein Quality Attributes, Rui Fang

Doctoral Dissertations

Lyophilization has been used to improve the quality of pharmaceutical proteins when sufficient stability in the aqueous state cannot be achieved. However, due to inherent challenges in both the freeze-drying process and formulation of proteins for freeze drying, efficient delivery of drug products with uniformly improved stability is not trivial. The overall objective of this work was to investigate freeze-dried protein quality attributes affected by stress factors arising from process and formulation.

The natural variation in ice nucleation temperature (T_n) necessitates the control of ice nucleation to ensure uniformity in product quality across a batch. Further, it is …