Digital Commons Network^™

Art That Heals, Christina Cardona

Capstones

Beryl Brenner was a creative arts therapist for 40 years, and helped veterans heal from war traumas through art all across the city. For the past 11 years, she was at the Brooklyn Campus of the VA NY Harbor Healthcare system in Bay Ridge, where she developed the art therapy program. https://christinacardona1.wordpress.com

Telling The Good News, Allyson R. Escobar

Capstones

In light of recent clergy abuse scandals, cover-ups and leadership shake-downs, it is a divided time in the Catholic Church: but this isn’t the whole story. My final capstone project is a critical essay of how Catholicism (and religion overall) is represented in mainstream media--particularly in secular news publications and entertainment (horror films) in the United States. By examining the coverage and how conversations differ within members of the Catholic Church--from journalists and critics to active Catholics, religious men and women--this project calls for greater accountability, fairness, faith representation in all media, and the overall claim that there are Catholic …

Dios, Drogas, Dinero: ¿QuiéN Gana Con El Traslado De Adictos De Puerto Rico A Ee.Uu.?, Claudia E. Irizarry Aponte, Eliana Y. Perez

Capstones

For the last 25 years, evangelical leaders have been shipping off opioid addicts in Puerto Rico to cities in the mainland US, mainly New York City, Chicago and Philadelphia--under the promise they’ll receive state-of-the-art rehabilitation treatment, only to end up in unregulated transitional homes and flophouses where they don’t receive proper medical care or psychotherapy. In turn, many of these unregulated transitional homes, also run by evangelical leaders, may charge Medicaid kickbacks from their “patients.”

While this so-called “air bridge” from Puerto Rico to the U.S. goes back decades, it gained momentum from 2005 to 2014, when evangelical leaders joined …

Public Charge Proposal Spawns “Chilling Effect” Within Immigrant Hiv Community, Say Service Providers, Karina Hernandez

Capstones

New regulations from the Trump administration are leaving immigrants living with HIV in New York City reluctant to continue or seek treatment, according to service providers.

Nursing Partnership With Patients, Parents And Families For Safety Through Simulation, Courtnay Caufield

Doctor of Nursing Practice (DNP) Projects

Abstract

Problem: The importance of communication between nurses, patients, and their family members with respect to treating each other as partners in safety cannot be overstated. It is imperative that families and patients feel empowered to speak up and report clinical errors at any time and be able to communicate effectively to prevent harm and encourage communication.

Context: This is especially important in the acute care setting, where patients may be in contact with multiple people and processes daily. Attention to this safety partnership can be established through improvements in patient satisfaction scores, which are usually collected from patients and …

Corrosion Of Hydraulic Steel Structures And Preventive Measures, Jackson Daniel Hinton

Theses and Dissertations

Hydraulic steel structures (HSS) are key components of U.S. Army Corps of Engineers infrastructure and are subject to corrosive environments, unpredictable loadings, and extreme conditions. Corrosion can take many forms and can cause costly damage to HSS due to inadequate design of protective measures. There are numerous forms of corrosion that have a negative effect on HSS, as well as material properties that need consideration when design HSS preventive measures. Understanding corrosion and providing proper preventive measures is crucial for HSS. Proper maintenance and repair of these protection systems also play a significant part in corrosion control of HSS.

Implementing A Surgical Infection Prevention Practice In An Integrated Healthcare System, Tammy Peacock

Doctor of Nursing Practice (DNP) Projects

Problem: One of the most preventable health care associated infections (HAI) is surgical site infection (SSI). Approximately sixty percent of SSI’s could be prevented. The devastation of an SSI to the patient can be catastrophic. The cost to the health care system for treating SSI’s can be substantial (Ban et al., 2017).

Context: The rate of surgical site infections has been on the increase over the past three years. The concern for the amount of harm affecting our patients was worrisome. The cost of reputation and the bottom line to the organization was recognized by senior leadership. The support from …

Teamstepps: A Foundation For Shared Governance In A High-Risk Obstetrical/Neonatal Service Line, Genevieve Wright

Doctor of Nursing Practice (DNP) Projects

Abstract

Problem: Declining registered nurse (RN) engagement in the maternal child health (MCH) department, despite improvements in RN staffing, some reductions in nurse-patient ratios, the addition of support staff resources, and a focus on quality and safety.

Context: The project setting is an MCH department of a 184-bed community hospital, part of a large national organization, serving a diverse population in Northern California. The initial stakeholders included RNs, managers, and assistant managers; the team was later expanded as the project developed (see Appendix A).

Intervention: The original aim of this project was to improve nurse engagement among frontline nurses through …

Improving Management Of Obstetrical Emergencies: Using Simulation-Based Training, Amira Amatullah

Doctor of Nursing Practice (DNP) Projects

The aim of this Executive Leadership Doctorate in Nursing Practice project was to assess the effectiveness of simulation-based training as a strategy to ensure patient safety and quality care by improving the knowledge and confidence of obstetric nursing staff. Collateral goals included the development of a simulation-based interactive training program to improve staff response to obstetric emergencies and the establishment of an Interprofessional Simulation Training Center.

The use of simulation-based training is widely accepted ans used in healthcare education. Several benefits of simulation-based training include a learner-centered approach, safe acquisition of technical skills training and development of effective communication skills. …

Walker, Dorian (Fa 1240), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 1240. Collection of oral history interviews with railroad employees, locals, and historians recorded on Betacam and Betacam SP for Dorian Walker’s 1995 film Beauty of the Southland. Portions of the interviews were also used for a 2010 miniseries, All Aboard.

Bastin, Glen (Fa 1241), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 1241. Collection of 38 cassette tapes featuring Glen Bastin's regional public affairs syndicated radio program, "Pondering Kentucky: The Magazine." A contents list was prepared and appears at the end of this finding aid.

The Struggle Is Eternal, Joseph R. Fitzgerald

Civil Rights

Many prominent and well-known figures greatly impacted the civil rights movement, but one of the most influential and unsung leaders of that period was Gloria Richardson. As the leader of the Cambridge Nonviolent Action Committee (CNAC), a multifaceted liberation campaign formed to target segregation and racial inequality in Cambridge, Maryland, Richardson advocated for economic justice and tactics beyond nonviolent demonstrations. Her philosophies and strategies—including her belief that black people had a right to self–defense—were adopted, often without credit, by a number of civil rights and black power leaders and activists.

The Struggle Is Eternal: Gloria Richardson and Black Liberation explores …

2018 Fall Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Fall 2017 commencement program. Commencement was on Friday, December 14, 2018.

Meeting Minutes - 12/14/2018, Magnolia Steering Committee

Steering Committee Meetings

No abstract provided.

Mineralogy, Petrology, And Geochemistry Of The Unique Silica-Rich Ungrouped Achondrite Northwest Africa 11575, Mya Ann Habermann

Earth and Planetary Sciences ETDs

We report here on a unique, newly discovered, silica-rich ungrouped achondrite Northwest Africa 11575 (NWA 11575). NWA 11575 is one of four known silica-rich ungrouped achondrites, presenting evidence for igneous processes resulting in evolved compositions early in the history of the solar system. It is unique from the other silica-rich ungrouped achondrites in that it has pyroxene compositional trends matching those of lunar samples and martian meteorites; contains quartz and potassium feldspar; and contains oxygen, hydrogen, and chromium isotopes that are similar to those of LL chondrites. Together, these four silica-rich ungrouped achondrites provide evidence for evolved compositions resulting from …

Plus Ça Change: A Century-Old Removal For Cause, Michael E. Herz

Online Publications

Lots of ink has been spilled over when Congress can give federal officials for-cause protection. One would think that a necessary antecedent to that discussion would be a determination of exactly what for-cause protection entails. What is “inefficiency, neglect of duty, or malfeasance in office”? Yet no one knows; the debate over the permissibility of that restriction proceeds in blissful uncertainty as to its scope.

Land Mollusks Of The California Channel Islands: An Overview Of Diversity, Populations, And Conservation Status, Charles A. Drost, Jeffrey C. Nekola, Barry Roth, Timothy A. Pearce

Western North American Naturalist

The land snails and slugs have the highest level of endemism among all major animal groups on the California Channel Islands, with nearly 75% of the native terrestrial species confined to one or more of the 8 islands. In spite of this endemism, and in spite of the rarity of some species, the snails and slugs are one of the most poorly known groups. We present the first comprehensive overview of the land mollusk fauna of the Channel Islands, along with the results of recent intensive inventory studies. Surveys on San Clemente Island have increased the number of land mollusk …

Development Of Polymeric Carriers For The Treatment Of Acute Kidney Injury, Yi Chen

Theses & Dissertations

Acute kidney injury (AKI) is a major kidney disease associated with high mortality and morbidity. Long-term AKI may lead to chronic kidney disease and end-stage renal disease. Several clinical trials failed due to lack of efficacy and undesired side effects. Studies showed that macromolecular delivery systems would be a promising method to target kidney, however, little is known about how physicochemical properties affects the polymers deposition in ischemia-reperfusion (I/R) AKI.

Gene therapy has been well studied as a promising therapeutic agent for several diseases, including cancer and AKI. Although small interfering RNA (siRNA) has been commonly used to treat AKI …

Dietary Polyunsaturated Fatty Acids Regulate Mammary Tumor Growth And Metastasis By Modulating Tissue Microenvironments, Saraswoti Khadge

Theses & Dissertations

Omega (ω)-6 and ω-3 polyunsaturated fatty acids (PUFAs) are essential fatty acids (FAs) and the precursors of pro- and anti-inflammatory mediators respectively. Epidemiological studies have shown a lower incidence of breast cancer (BC) in the countries where long-chain (LC)-ω-3FAs consumption is higher; however, the role of ω-3FAs in BC growth and metastasis is poorly understood. We used isocaloric, isolipidic ω-6 and ω-3 (contains LC-ω-3FAs) diets and a pair-fed model to evaluate the effects of dietary PUFAs in mammary tumor metastasis. Our studies have resulted in several novel observations including that dietary LC-ω-3FAs modulate mammary gland (MG) microenvironments in non-tumor bearing …

Delivery Of Microrna With Cxcr4-Targeted Nanoparticles In Metastatic Cancer Treatment, Ying Xie

Theses & Dissertations

Metastasis is the main contributor to cancer-associated deaths. Inhibition of CXCR4 emerged as one promising approach in metastatic cancer therapy. MiRNAs represent a new class of therapeutics for cancer treatment through RNA interference-mediated gene silencing. Polymeric CXCR4 antagonist (PCX) is a dual-functional polycation to inhibit CXCR4 and deliver nucleic acids. This dissertation hypothesized that blockade of CXCR4 by PCX combined with delivery of miRNA cooperatively enhances metastatic cancer therapy.

In chapter 1, an overview of CXCR4 inhibition, miRNA delivery and CXCR4 targeted nanomedicine in cancer therapy is given.

Chapter 2 reports that PCX can effectively deliver miR-200c mimic and that …

Development Of Chloroquine-Containing Hpma Copolymers For Drug Delivery, Fei Yu

Theses & Dissertations

Abstract

Development of Chloroquine-containing HPMA Copolymers for Drug Delivery

Fei Yu, Ph.D.

University of Nebraska Medical Center, 2018

Supervisor: David Oupický, Ph.D.

Synthetic polymers have been extensively explored for improved delivery of anticancer agents. Polymers can be designed as either carriers of existing drugs or as polymeric drugs with intrinsic pharmacological activity. Advantages of such polymeric drugs include common positive features of polymer-drug conjugates, such as targeted delivery of drugs, altered pharmacokinetic and biodistribution, improved drug safety, but also favorable pharmacological activities due to multivalent receptor-ligand interactions.

Chloroquine (CQ) and hydroxychloroquine (HCQ) are safe drugs that have been in clinical …

Increasing Physical Activity To Improve Health Through Primary Care Clinics In Rural Nebraska, Jill Reed

Theses & Dissertations

Addressing the lack of physical activity (PA) in rural adults is vital because of the role it plays in the risk for many chronic diseases. The purpose of the study was to explore the feasibility of conducting a 12-week intervention to increase PA behavior in inactive rural adults recruited from a primary care clinic. Subjects were randomized to the intervention (n=30) or control (n=29) group and wore a Fitbit to track PA. The intervention group completed action plans and received weekly motivational text messages to improve PA behaviors. Semi-structured interviews were conducted with study participants (n=10) and a focus group …

Essays On The Patient-Centered Medical Home In The United States Military Health System, Glen N. Gilson

Theses & Dissertations

The Patient-Centered Medical Home has been endorsed by the primary care community as the model of the future, with hopes that it will increase quality of care and the patient and provider experience while decreasing costs. Many aspects of the implementation of the Patient-Centered Medical Home model remain unexplored. This dissertation comprises three independent studies examining Patient-Centered Medical Home implementation in the Military Health System, including (1) the effects of environmental correlates on the time to implement the model, (2) the impact of differences in implementation on preventive care quality outcomes, and (3) the effect of differences in implementation on …

An Assessment Of Preparations Made In The United States For Highly Hazardous Communicable Diseases Following The 2014-2016 Ebola Virus Disease Epidemic, Jocelyn J. Herstein

Theses & Dissertations

The 2014-2016 Ebola virus disease (EVD) epidemic in West Africa was unprecedented in magnitude and scope. The threat of imported cases of EVD in the United States prompted the Centers for Disease Control and Prevention (CDC) to establish a tiered network of hospitals to enhance domestic isolation capacity, including the designation of select hospitals as Ebola treatment centers (ETCs). As of spring 2015, no information existed on the capacity, physical infrastructure, staffing models, or infection control protocols of these newly-established ETCs, nor was there information on other highly hazardous communicable diseases (HHCDs) these units would admit. Moreover, no documentation was …

Delineation Of New Mechanisms Of Dna Double Strand Break Repair, Songli Zhu

Theses & Dissertations

DNA damage is frequently induced in cells by both endogenous and exogenous agents. DNA damage, particular double strand breaks (DSBs) may lead to genomic instability, and the progression of cancer, aging, neurodegeneration, and other human diseases. The cell employs two major DSB repair pathways, including homologous recombination (HR) and Non-homologous end joining (NHEJ), but the detailed mechanisms of DSB repair remain to be further revealed.

In the first part of this study, we characterized a plasmid-based assay to investigate NHEJ repair in Xenopus egg extracts. Our data argued for a preference for the precise repair by the NHEJ machinery and …

Quantification Of Lutein + Zeaxanthin Presence In Human Placenta And Correlations With Blood Levels And Maternal Dietary Intake, Melissa Thoene

Theses & Dissertations

Lutein + zeaxanthin are carotenoids most recognized in eye health, but less is known about their status and transfer during pregnancy. While quantified in maternal and umbilical cord blood, they have never been analyzed in placenta tissue. Therefore, the purpose of this dissertation is to firstly quantify lutein + zeaxanthin concentrations in human placenta and to later correlate with levels in maternal dietary intake, maternal serum, and umbilical cord blood. Proportions of lutein + zeaxanthin will also be compared within diet, placenta, maternal serum, and umbilical cord blood among additionally analyzed carotenoids including lycopene, β-cryptoxanthin, α-carotene, and β-carotene. Lutein + …

Intra- And Inter-Molecular Signaling In A Cardiac Connexin: Role Of Cytoplasmic Domain Dimerization And Phosphorylation, Andrew J. Trease

Theses & Dissertations

As critical mediators of cell-to-cell communication, gap junctions (GJs) are comprised of membrane channels that directly link the cytoplasm of adjacent coupled cells thereby allowing for the passage of ions, small metabolites, and secondary messengers. Each channel is formed by the apposition of two connexons from adjacent cells, each composed of six connexin (Cx) proteins. Each GJ channel functions to promote signal propagation and synchronization of cells and tissues in organs. Furthermore, GJs are essential for proper propagation of cardiac action potentials from one cell to the next, leading to the coordinated contraction and relaxation of heart muscle powering circulation. …

Hearing Loss And Hearing Protection Use Among Midwestern Farmers, Josie J. Ehlers

Theses & Dissertations

Many farmers have noise-induced hearing loss, yet few use hearing protection when working around loud noise. A point source intervention (storing hearing protection devices near sources of noise) was implemented to help farmers overcome accessibility barriers related to using hearing protection. Intervention farmers (n=53) received education and the point source intervention; control farmers (n=36) received education only. During each year of the study, all farmers completed a questionnaire about their perceptions of hearing protection and participated in an audiometric test at their farm. Ambient sound pressure levels were taken during tests. The main objectives of this dissertation were to evaluate …

Student Perspectives On Working In Interdisciplinary Teams To Implement Mhealth, Elina Chun

Undergraduate Honors Theses

Interprofessional education of students in healthcare professions can lead to positive outcomes for students that are unique in a university setting. The purpose of this thesis is to describe benefits and challenges students encounter when working with students of other majors. This study used a convenience sample of students working on a university project to implement mHealth. Participants responded to two surveys with quantitative and qualitative questions. Students reported greater appreciation for diversity, the necessity of communication skills, and self-awareness of their own responsibilities in a team.

Evidence-Based Curriculum And Its Impact On Risky Behaviors And Stress Among Hispanic College Students, Marivic B. Torregosa, Marcus Antonius Ynalvez, Christopher Craddock, Nandita Chaudhuri, David Cabrera, Maria Del Rosaro Benavides, Dora Maria Ramirez

International Nursing Research Congress (INRC)

To present the results of an evidence-based intervention on the risky behaviors and perceived stress among young Hispanic residents in a US southern border city.