Digital Commons Network^™

Transgenic Mice Overexpressing Human Tnf-Α Experience Early Onset Spontaneous Intervertebral Disc Herniation In The Absence Of Overt Degeneration., Deborah J. Gorth, Irving M. Shapiro, Makarand V. Risbud

Department of Orthopaedic Surgery Faculty Papers

There is a well-established link between cytokine expression and the progression of intervertebral disc degeneration. Among these cytokines, interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) are the most commonly studied. To investigate whether systemic hTNF-α overexpression affects intervertebral disc health, we studied the spine phenotype of Tg197 mice, a widely used hTNF-α transgenic line. These mice were studied at 12-16 weeks of age using comprehensive histochemical and immunohistological analysis of the spinal motion segment. Micro-CT analysis was performed to quantify vertebral trabecular bone architecture. The Tg197 mice evidenced spontaneous annular tears and herniation with increased vascularity in subchondral bone and …

Trypanosoma Brucei Prmt1 Is A Nucleic Acid Binding Protein With A Role In Energy Metabolism And The Starvation Stress Response., Lucie Kafková, Chengjian Tu, Kyle L. Pazzo, Kyle P. Smith, Erik W. Debler, Kimberly S. Paul, Jun Qu, Laurie K. Read

Department of Biochemistry and Molecular Biology Faculty Papers

In Trypanosoma brucei and related kinetoplastid parasites, transcription of protein coding genes is largely unregulated. Rather, mRNA binding proteins, which impact processes such as transcript stability and translation efficiency, are the predominant regulators of gene expression. Arginine methylation is a posttranslational modification that preferentially targets RNA binding proteins and is, therefore, likely to have a substantial impact on T. brucei biology. The data presented here demonstrate that cells depleted of T. brucei PRMT1 (TbPRMT1), a major type I protein arginine methyltransferase, exhibit decreased virulence in an animal model. To understand the basis of this phenotype, quantitative global proteomics was employed …

Syndemics Of Severity And Frequency Of Elder Abuse: A Cross-Sectional Study In Mexican Older Females, Mireya Vilar-Compte, Pablo Gaitán-Rossi

Department of Public Health Scholarship and Creative Works

Background: Elder abuse is a common phenomenon with important effects on the health and well-being of older adults. There are important gaps in elder abuse measurement, as it is usually reported as the absence or presence of elder abuse, disregarding its severity and frequency.

Objectives: Identify different ways of measuring severity and frequency of elder abuse and assess whether different experiences of severity and frequency suggest syndemic relationships.

Methods: Through a sample of 534 non-institutionalized Mexican older women, we assessed how severity (i.e., number of abusive experiences and number of types of abuses) and frequency (i.e., if abusive experiences had …

From Sex Objects To Sisters-In-Arms: Reducing Military Sexual Assault Through Integrated Basic Training And Housing, Gabrielle Lucero

Duke Journal of Gender Law & Policy

No abstract provided.

Voluntary Sterilization Of Inmates For Reduced Prison Sentences, Elise B. Adams

Duke Journal of Gender Law & Policy

In May 2017, a Tennessee judge issued a standing order allowing inmates to receive thirty days’ jail credit in exchange for undergoing a voluntary sterilization procedure. Although the order was ultimately rescinded, this Article will address the constitutional and ethical concerns that a district court would have considered had the order not been rescinded. While inmates can always choose to waive their constitutional rights, the coercive nature of prisons—explained in the unconstitutional conditions doctrine—may compromise a prisoner’s ability to provide voluntary consent. The constitutionality of the order largely depends on the level of scrutiny a court applies. Regardless of the …

Using Federal Nondiscrimination Laws To Avoid Erisa: Securing Protection From Transgender Discrimination In Employee Health Benefit Plans, Bridget Schaaff

Duke Journal of Gender Law & Policy

Recent attempts to repeal the Affordable Care Act and the potential rollback of the interpretation of the protections the Act affords transgender people put transgender people at risk of being denied services and coverage for gender-affirming care. This Article provides advocates with alternative legal arguments to help employees bring claims when their employer provides a health benefit plan that discriminates on the basis of gender identity. These arguments can avoid the Employee Retirement Income Security Act’s broad preemption scheme and lack of nondiscrimination provisions. This Article proposes that, based on a narrow exception to preemption regarding the Employee Retirement Income …

Journal Staff

Duke Journal of Gender Law & Policy

No abstract provided.

Repeats Of Unusual Size In Plant Mitochondrial Genomes: Identification, Incidence And Evolution, Emily L. Wynn, Alan C. Christensen

School of Biological Sciences: Faculty Publications

Plant mitochondrial genomes have excessive size relative to coding capacity, a low mutation rate in genes and a high rearrangement rate. They also have abundant non-tandem repeats often including pairs of large repeats which cause isomerization of the genome by recombination, and numerous repeats of up to several hundred base pairs that recombine only when the genome is stressed by DNA damaging agents or mutations in DNA repair pathway genes. Early work on mitochondrial genomes led to the suggestion that repeats in the size range from several hundred to a few thousand base pair are underrepresented. The repeats themselves are …

Deep Visual Recommendation System, Raksha Sunil

Master's Projects

Recommendation system is a filtering system that predicts ratings or preferences that a user might have. Recommendation system is an evolved form of our trivial information retrieval systems. In this paper, we present a technique to solve new item cold start problem. New item cold start problem occurs when a new item is added to a shopping website like Amazon.com. There is no metadata for this item, no ratings and no reviews because it’s a new item in the system. Absence of data results in no recommendation or bad recommendations. Our approach to solve new item cold start problem requires …

State V. Washington Appellant's Reply Brief Dckt. 45947

Not Reported

No abstract provided.

State V. Dilka Appellant's Reply Brief Dckt. 45971

Not Reported

No abstract provided.

State V. Ratliff Appellant's Brief Dckt. 45996

Not Reported

No abstract provided.

Assessing Ground Penetrating Radar’S Ability To Image Subsurface Characteristics Of Icy Debris Fans In Alaska And New Zealand, Robert W. Jacob, Jeffrey M. Trop, R. Craig Kochel

Faculty Journal Articles

Icy debris fans have recently been described as fan shaped depositional landforms associated with (or formed during) deglaciation, however, the subsurface characteristics remain essentially undocumented. We used ground penetrating radar (GPR) to non-invasively investigate the subsurface characteristics of icy debris fans (IDFs) at McCarthy Glacier, Alaska, USA and at La Perouse Glacier, South Island of New Zealand. IDFs are largely unexplored paraglacial landforms in deglaciating alpine regions at the mouths of bedrock catchments between valley glaciers and icecaps. IDFs receive deposits of mainly ice and minor lithic material through different mass-flow processes, chiefly ice avalanche and to a lesser extent …

Multimodal Nondestructive Dry Cask Basket Structure And Spent Fuel Evaluation, J. Gladden, James Tulenko, Lingyu Yu, Haori Yang

Faculty and Student Publications (Open Access)

No abstract provided.

Spatial And Temporal Analysis Of Precipitation And Effective Rainfall Using Gauge Observations, Satellite, And Gridded Climate Data For Agricultural Water Management In The Upper Colorado River Basin, Mahyar Aboutalebi, Alfonso F. Torres-Rua, L. Niel Allen

Civil and Environmental Engineering Faculty Publications

Accurate spatial and temporal precipitation estimates are important for hydrological studies of irrigation depletion, net irrigation requirement, natural recharge, and hydrological water balances in defined areas. This analysis supports the verification of water savings (reduced depletion)from deficit irrigation of pastures in the Upper Colorado River Basin. The study area has diverse topography with scattered fields and few precipitation gauges that are not representative of the basin.Gridded precipitation products from TRMM-3B42, PRISM, Daymet, and gauge observations were evaluated on two case studies located in Colorado and Wyoming during the 2014–2016 irrigation seasons. First, the resolution at the farm level is discussed. …

From The Streets To The Chamber: Social Movements And The Mining Ban In El Salvador, Rose J. Spalding

College of Liberal Arts and Social Sciences Faculty and Staff Works

Following an extended anti-mining campaign, El Salvador became the first country to adopt a legal ban on all forms of metallic mining. This article uses process tracing to map direct, indirect and mediated linkages between the anti-mining mobilization and the formal adoption of a mining prohibition by the national legislature in 2017. It draws on 78 interviews with campaign activists, legislators, government officials, business leaders and legal teams, and combines this information with legislative documents and reports, public opinion data, legal documents from an investment dispute filed against the Salvadoran government, and blogs and website of the Mesa Nacional Frente …

Slower Alpha Rhythm Associates With Poorer Seizure Control In Epilepsy, E Abela, Ad Pawley, C Tangwiriyasakul, Sn Yaakub, Et Al

School of Psychology

Objective Slowing and frontal spread of the alpha rhythm have been reported in multiple epilepsy syndromes. We investigated whether these phenomena are associated with seizure control. Methods We prospectively acquired resting-state electroencephalogram (EEG) in 63 patients with focal and idiopathic generalized epilepsy (FE and IGE) and 39 age- and gender-matched healthy subjects (HS). Patients were divided into good and poor (≥4 seizures/12 months) seizure control groups based on self-reports and clinical records. We computed spectral power from 20-sec EEG segments during eyes-closed wakefulness, free of interictal abnormalities, and quantified power in high- and low-alpha bands. Analysis of covariance and post …

Rapid Detection Of Extra-Intestinal Pathogenic Escherichia Coli Multi-Locus Sequence Type 127 Using A Specific Pcr Assay., Rw O'Hara, Peter J. Jenks, Matthew Emery, Mathew Upton

School of Biomedical Sciences

PURPOSE: Members of the ST127 uropathogenic E. coli (UPEC) clone have a high virulence potential and are also highly virulent in insect infection models. However, strains of this lineage are reported in relatively low numbers in many studies. ST127 strains are also usually widely susceptible to antibiotics and, consequently, their true prevalence may be under-recognized as they will be eradicated during empirical therapy. A genuine concern is the possibility that members of this highly virulent lineage will acquire resistance, leading to a more serious threat. The aim of this study was to design and validate a PCR assay specific to …

Trevo 2000: Results Of A Large Real-World Registry For Stent Retriever For Acute Ischemic Stroke., Mandy J Binning, Bruno Bartolini, Blaise Baxter, Ronald Budzik, Joey English, Rishi Gupta, Hirad Hedayat, Antonin Krajina, David Liebeskind, Raul G Nogueira, Ryan Shields, Erol Veznedaroglu

OhioHealth Research Institute Articles

Background Recent randomized controlled trials show benefit of thrombectomy for large vessel occlusion in stroke. Real-world data aid in assessing reproducibility of outcomes outside of clinical trials. The Trevo Retriever Registry is a multicenter, international, prospective study designed to assess outcomes in a large cohort of patients. Methods and Results The Trevo Registry is a prospective database of patients with large vessel occlusion treated with the Trevo device as the first device. The primary end point is revascularization based on modified Thrombolysis in Cerebral Infarction score and secondary end points include 90-day modified Rankin Scale, 90-day mortality, neurological deterioration at …

Banks - Bulloch County Bank

Bulloch County Papers

This is the digital file of the Statesboro-Bulloch County Library's Public History Files. Many of the items within are news articles from the Statesboro Herald Newspaper or its predecessors.

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Reports on A Serious Flaw in Nutrition Epidemiology: A Meta-Analysis Study

• Georgia Southern Reports on Role of Local Boards of Health in community Partner Engagement for Local Health Departments

Gender Differences In Patient-Reported Outcomes Among Adults With Atherosclerotic Cardiovascular Disease, Joseph Salami

All Publications

Background

Atherosclerotic cardiovascular disease ( ASCVD ) accounts for approximately one third of deaths in women. Although there is an established relationship between positive patient experiences, health-related quality of life, and improved health outcomes, little is known about gender differences in patient-reported outcomes among ASCVD patients. We therefore compared gender differences in patient-centered outcomes among individuals with ASCVD.

Methods and Results

Data from the 2006 to 2015 Medical Expenditure Panel Survey, a nationally representative US sample, were used for this study. Adults ≥18 years with a diagnosis of ASCVD , ascertained by International Classification of Diseases, Ninth Revision ( ICD-9) …

Provision Of Reference And Information Services To The Physically Challenged Persons In Nigeria: Challenges And Prospects, Ogagaoghene U. Idhalama

Library Philosophy and Practice (e-journal)

Abstract

This paper examines the provision of reference and information services to the physically challenged persons in Nigeria: Challenges and prospects. The article demystifies the conceptual framework of information services and physically challenged persons, the information needs of the physically challenged as a concept was succinctly analyzed and the attention or relegation received by this group of library users discussed. The public library for instance is there to provide its services to all classes of users irrespective of age, sex, colour and disability. This paper is therefore timely as it ascertained how all libraries can help to meet up with …

Problems Caused By The Students’ Use Of Cell Phones In University Libraries In Anambra State, Nigeria., Ndidi Grace Nwankwo Cln, Regina Eyiuche Obiadazie, Julius Okeke Ofordile Cln

Library Philosophy and Practice (e-journal)

ABSTRACT

This study sought information from respondents on the problems caused by the students use of cell phones in university libraries in Anambra State of Nigeria. The study adopted descriptive survey research design, that traced the history of cell phones in Nigeria. The population of 3000 registered student’s library users was studied. Sample size of 100 respondents was used. Accidental sampling technique was used to collect data. A self-constructed questionnaire, validated by two experts from the university library was used for data collection from the sampled students. The reliability of the instrument was tasted in Imo State University Library using …

Singularity Resolution In Anisotropic And Black Hole Spacetimes In Loop Quantum Cosmology, Sahil Saini

LSU Doctoral Dissertations

Loop quantum cosmology (LQC) has in recent years led to successful resolution of singularities in cosmological models while agreeing with general relativity in low curvature limit. Existence of a bounce and the possibility of an effective continuum description closely approximating the quantum evolution have been notable features of this singularity resolution. The effective spacetimes of loop quantized isotropic and Bianchi-I models have been shown to be geodesically complete and free from strong singularities. In this dissertation, we extend these results to effective loop quantized Bianchi-II, Bianchi-IX and Kantowski--Sachs models with arbitrary minimally coupled matter, and also explore the possibility of …

Temperature Transient Analysis For Reservoir Characterization, Yilin Mao

LSU Doctoral Dissertations

Recent developments in downhole temperature measurements open new alternatives contributing to reservoir characterization. In this dissertation, novel forward and inverse models to analyze production- and injection-induced temperature signals are developed for conventional and unconventional reservoir applications. Important limitations of the proposed models are addressed by accounting for fluid property variations and complex production strategies.

Forward modeling approaches involve making relevant assumptions that allow rigorous analytical solutions to be constructed using Laplace transform, Method of Characteristics, and control volume analysis. Our results of the analytical models are benchmarked with those from commercial numerical simulation software. Multiple possible scenarios of conventional reservoirs …

Advent Joy: The Joy Of The Incarnation Is In Tents, Howard Schaap

Faculty Work Comprehensive List

"If the Christmas story in Luke is framed with joy, there is a different kind of joy in John, a strange kind, the joy of tent-living."

Posting about ­­­­­­­­finding our security in Christ from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/advent-joy-the-joy-of-the-incarnation-is-in-tents/

Matter Dis//Assembled: Revealing The Economies And Ecologies Of Aluminum, Noah Anderson

Architecture Thesis Prep

This project seeks to understand matter through the environments it creates. These environments, created through production, end-use, and disposal, extend to the scale of the world, the territory and the product. In a globalized world, the separate environments of a single material are highly external, and while we may know where a material comes from, the consequences of its extraction and manufacture are out-of-site, out-of-mind. This externalization is evident for Aluminum, which has a diverse and often contradictory range of environments.

Method For Filtering Displayed Content Based On Occupants, Scott Randolph, Bradley Stenning, Steve Paik

Defensive Publications Series

This publication describes an operating system (OS) that re-defines a user as a sum of all occupants in a shared space, and not merely as a single individual who has signed into a shared device. To identify the occupants of a space, the OS uses objective markers, such as: facial recognition, radar signature, biometric sensors, media address control identification (MAC ID), voice recognition, various sensors, radio-frequency identification (RFID), or other Internet-of-Things (IoT) data. Then, the OS filters out the displayed content on the shared device based on a level of trust amongst the occupants and a level of sensitivity. To …

Determining Breakpoints In Media Content, Migle Padegimaite, Sammy El Ghazzal

Defensive Publications Series

Systems and methods for determining breakpoints in media content via a machine learning architecture by accounting for the context of the media content, and for placing separate pieces of additional content into the breakpoints, are described. The machine learning architecture determines the number of pieces of additional content to insert into the media content, divides the media content into a number of scenes and tags each scene with appropriate identifiers based on comparison to reference content, identifies break points at the end of each scene, identifies which break point to insert pieces of additional content into, and then inserts the …