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Nano-Graphene Oxide And Vitamin D Delivery, Reza Mahdavi, Mehran Solati-Hashjin, Meisam Omidi, Arash Khojasteh, Fateme Fayyazbakhsh

Mechanical and Aerospace Engineering Faculty Research & Creative Works

One of the Most Interesting and Recent Insights into Biomimetic Scaffold Nano-Biomaterial is Smart Scaffolding with Targeted Drug Delivery Ability. in Recent Decades, the Use of Graphene-Based Materials, Such as Nano-Graphene Oxide (NGO), as a Drug Carrier with Amphiphilic Properties, Has Attracted Considerable Attention of Scientists and Researchers in This Field. in Addition, One of the Important Global Problems is Increased Vitamin D Deficiency, Particularly in Pregnant and Postmenopausal Women. Therefore, in This Work, by Considering Hydrophobic Properties of Vitamin D, We Attempted to Examine its Loading and Release Both in the Presence of Surfactant and Surfactant-Free NGO-Aqueous Solution. at …

Numbers Are Just Not Enough: A Critical Analysis Of Race, Gender, And Sexuality In Elementary And Middle School Health Textbooks, Sherry L. Deckman, Ellie Fitts Fulmer, Keely Kirby, Katharine Hoover, Abena S. Mackall

Publications and Research

Textbooks are a multimillion dollar publishing business in the United States. Even as 21st-century classrooms become more multimodal, digital and hardcopy textbooks remain a key feature of American education. Consequently, classroom textbooks have been shown to control knowledge dissemination across the content areas. In particular, health texts have been uniquely shown to communicate values that validate or marginalize students and encourage healthy or harmful activity. Thus,what textbook makers choose to include as worthy of study, and how they portray various groups of people with regard to race, gender, and sexuality has societal implications. Employing quantitative and qualitative content analysis methods, …

Noncontact Three-Dimensional Diffuse Optical Imaging Of Deep Tissue Blood Flow Distribution, Guoqiang Yu, Yu Lin, Chong Huang

Biomedical Engineering Faculty Patents

The present invention provides for three-dimensional reflectance diffuse optical imaging of deep tissue blood flow distribution that removes the need for probe-tissue contact, thereby allowing for such technology to be applied to sensitive, vulnerable, damaged, or reconstructive tissue. The systems utilize noncontact application and detection of near-infrared light through optical lens and detection through a linear array or two-dimensional array of avalanche photodiodes or a two-dimensional array of detectors provided by charge-coupled-device (CCD). Both further feature a finite-element-method (FEM) based facilitation to provide for three-dimensional flow image reconstruction in deep tissues with arbitrary geometries.

Study Examines Obesity And Reproductive Status Of Zoo Elephants, Staff

Browse All News

No abstract provided.

Triple Pancreatic Walled-Off Fluid Collections Treated Simultaneously With Endoscopic Transmural Drainage., Sameen Khalid, Aamer Abbass, Eric Nellis Md, Shashin Shah Md, Hiral N. Shah Md

Department of Medicine

Pancreatic pseudocysts and walled-off pancreatic necrosis arise as a complication of pancreatitis. Multiple fluid collections are seen in 5-20% of the patients who have walled-off peripancreatic fluid collections. There is a paucity of data regarding the role of endoscopic transmural drainage in the management of multiple pancreatic fluid collections. In this case report, we present the case of a 72-year-old male with three walled-off pancreatic fluid collections in the setting of acute necrotizing pancreatitis. The patient underwent simultaneous endoscopic ultrasound-assisted cyst gastrostomy and cyst duodenostomy and aggressive irrigation without index endoscopic necrosectomy of the three peripancreatic fluid collections. Significant improvement …

Hubungan Status Gizi Dan Kesehatan Dengan Kualitas Hidup Lansia Di Dua Lokasi Berbeda, Nursilmi Nursilmi, Clara M. Kusharto, Cesilia Meti Dwiriani

Media Kesehatan Masyarakat Indonesia

Kualitas hidup lansia dipengaruhi oleh status gizi dan penyakit. Penelitian ini bertujuan mengidentifikasi perbedaan karakteristik subjek, status gizi, status kesehatan dan kualitas hidup serta mengkaji hubungan status gizi dan kesehatan dengan kualitas hidup lansia di Desa Ciherang Bogor dan Desa Jambu Bengkulu Tengah, dengan pertimbangan perbedaan etnis dan kebiasaan makan. Penelitian menggunakan desain cross sectional dengan 74 subjek di masing-masing desa. Pengumpulan data karakteristik subjek, status kesehatan, status gizi dan kualitas hidup menggunakan kuesioner. Analisis data menggunakan uji mann whitney dan korelasi spearman. Terdapat perbedaan signifikan karakteristik subjek dalam hal status perkawinan, pendidikan, pekerjaan dan status tinggal (p<0,05). Status gizi dan kualitas hidup yang baik pada subjek di Desa Ciherang lebih banyak dibandingkan di Desa Jambu. Terdapat perbedaan signifikan status gizi lansia (p<0,05) dan tidak terdapat perbedaan signifikan status kesehatan lansia (p>0,05). …

Intervensi Susu Tinggi Protein Terhadap Tingkat Konsumsi Zat Gizi Makro Dan Status Gizi Pada Kelompok Usia Dewasa, Harna Harna, Clara M. Kusharto, Katrin Roosita

Media Kesehatan Masyarakat Indonesia

Susu tinggi protein merupakan makanan kompleks yang mengandung beberapa senyawa bioaktif potensial, kemungkinan memiliki efek terhadap berat badan. Tujuan penelitian adalah untuk menganalisis pengaruh pemberian susu tinggi protein terhadap tingkat konsumsi susu tinggi protein, status gizi dan menganalisis hubungan antara tingkat konsumsi zat gizi makro dengan status gizi. Penelitian ini menggunakan metode eksprimental dengan desain Randomized Control Trial (RCT). Subjek dibagi menjadi dua kelompok yaitu 24 subjek pada kelompok perlakuan dan 23 subjek pada kelompok kontrol. Kelompok perlakuan diberikan susu tinggi protein dan pendidikan gizi selama 90 hari. Kelompok kontrol diberikan pendidikan gizi. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan …

Konsumsi Ikan Pada Ibu Hamil Dan Kaitannya Dengan Outcome Kelahiran, Rendra Kusuma, Ali Khomsan, Lilik Kustiyah

Media Kesehatan Masyarakat Indonesia

Konsumsi ikan ibu hamil yang rendah menjadi faktor risiko yang kuat pada kejadian persalinan prematur dan bayi berat lahir rendah. Tujuan dari penelitian ini mengetahui faktor yang memengaruhi outcome kelahiran. Penelitian ini didanai oleh Neys-van Hoogstraten Foundation. Desain penelitian ini adalah cohort study dengan jumlah subjek sebanyak 41 di Kecamatan Lenteng dan 38 ibu hamil di Kecamtan Kalianget, Kabupaten Sumenep. Data usia, pendidikan, pendapatan, ukuran rumah tangga, berat badan pra-hamil, dan paritas ibu diperoleh dengan wawancara menggunakan kuesioner, tinggi badan ibu menggunakan microtoise, asupan energi menggunakan recall 2x24 jam, konsumsi ikan menggunakan semi-quantitative food frequency questionnaire. Berat, panjang, …

Pengaruh Pola Makan Terhadap Kadar Kolesterol Total, Alodiea Yoeantafara, Santi Martini

Media Kesehatan Masyarakat Indonesia

Kadar Kolesterol total di dalam darah sangat berpengaruh terhadap pembentukan plak pada dinding pembuluh darah. Kadar kolesterol yang melebihi batas normal akan memicu terjadinya proses aterosklerosis, aterosklerosis merupakan manifestasi klinis dari Penyakit Jantung Koroner. Tujuan penelitian ini adalah menganalisis hubungan antara pola makan dengan kadar kolesterol total. Penelitian ini merupakan penelitian observasional analitik, menggunakan desain penelitian case control . Sampel penelitian ini sebesar 56 orang yang terdiri dari 28 kasus dan 28 kontrol. Sampel diambil secara acak menggunakan simple random sampling. Analisis data menggunakan uji statistik dan perhitungan OR dengan Epi Info. Hasil penelitian besar risiko kadar kolesterol total …

Efek Produk Galohgor Terhadap Aktivitas Antioksidan Dan Penurunan Stres Oksidatif Diabetes Melitus Tipe 2, Sulasyi Setyaningsih, Roosita Katrin, Evy Damayanthi

Media Kesehatan Masyarakat Indonesia

Hiperglikemi kronis pada penderita diabetes melitus tipe 2 meningkatkan terbentuknya radikal bebas yang disebabkan peningkatan peroksidasi asam lemak, yang akan mengarah pada komplikasi yang bersifat kronis. Peningkatan terbentuknya radikal bebas yang tidak diimbangi dengan peningkatan asupan antioksidan akan menimbulkan stres oksidatif. Penelitian dilakukan untuk menganalisis efek pemberian produk galohgor berupa cookies dan minuman serbuk terhadap status antioksidan dan penurunan penanda stres oksidatif pada penderita DM tipe 2. Sebanyak 18 subjek penderita DM tipe 2 dibagi menjadi 2 kelompok, yaitu kelompok intervensi (n=9) diberikan cookies dan minuman serbuk galohgor dan kelompok kontrol (n=9) diberi cookies dan minuman serbuk yang tidak mengandung …

Achieving Pregnancy Using Primary Care Interventions To Identify The Fertile Window, Thomas Bouchard, Richard J. Fehring, Mary Schneider

College of Nursing Faculty Research and Publications

Objective: To determine the effectiveness of achieving pregnancy with focused intercourse in the fertile window identified using natural fertility indicators. Methods: 24-cycle prospective effectiveness study. Setting: A North American web-based fertility monitoring service. Participants: 256 North American women aged 20–43 (mean age 29.2 years) seeking to achieve pregnancy. Intervention: Participants identified their fertile window with either electronic hormonal fertility monitoring or cervical mucus monitoring, or both, and recorded their observations on an online fertility tracking system. Main outcome measures: Pregnancies were validated by nurses with an online self-assessed pregnancy evaluation form. Survival analysis was used to determine pregnancy rates. Results: …

Is There A Link Between Aging And Microbiome Diversity In Exceptional Mammalian Longevity?, Graham M. Hughes, John Leech, Sébastien J. Puechmaille, Jose V. Lopez, Emma C. Teeling

Marine & Environmental Sciences Faculty Articles

A changing microbiome has been linked to biological aging in mice and humans, suggesting a possible role of gut flora in pathogenic aging phenotypes. Many bat species have exceptional longevity given their body size and some can live up to ten times longer than expected with little signs of aging. This study explores the anal microbiome of the exceptionally long-lived Myotis myotis bat, investigating bacterial composition in both adult and juvenile bats to determine if the microbiome changes with age in a wild, long-lived non-model organism, using non-lethal sampling. The anal microbiome was sequenced using metabarcoding in more than 50 …

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No abstract provided.

Is There A Link Between Aging And Microbiome Diversity In Exceptional Mammalian Longevity?, Graham M. Hughes, John Leech, Sebastien J. Puechmaille, Jose V. Lopez, Emma C. Teeling

Biology Faculty Articles

A changing microbiome has been linked to biological aging in mice and humans, suggesting a possible role of gut flora in pathogenic aging phenotypes. Many bat species have exceptional longevity given their body size and some can live up to ten times longer than expected with little signs of aging. This study explores the anal microbiome of the exceptionally long-lived Myotis myotis bat, investigating bacterial composition in both adult and juvenile bats to determine if the microbiome changes with age in a wild, long-lived non-model organism, using non-lethal sampling. The anal microbiome was sequenced using metabarcoding in more than 50 …

Feeding Immunity: Physiological And Behavioral Responses To Infection And Resource Limitation, Sarah A. Budischak, Christina B. Hansen, Quentin Caudron, Romain Garnier, Tyler R. Kartzinel, István Pelczer, Clayton E. Cressler, Anieke Van Leeuwen, Andrea L. Graham

School of Biological Sciences: Faculty Publications

Resources are a core currency of species interactions and ecology in general (e.g., think of food webs or competition). Within parasite-infected hosts, resources are divided among the competing demands of host immunity and growth as well as parasite reproduction and growth. Effects of resources on immune responses are increasingly understood at the cellular level (e.g., metabolic predictors of effector function), but there has been limited consideration of how these effects scale up to affect individual energetic regimes (e.g., allocation trade-offs), susceptibility to infection, and feeding behavior (e.g., responses to local resource quality and quantity). We experimentally rewilded laboratory mice (strain …

Does Exposure And Receptivity To E-Cigarette Advertisements Relate To E-Cigarette And Conventional Cigarette Use Behaviors Among Youth? Results From Wave 1 Of The Population Assessment Of Tobacco And Health Study, Nicole E. Nicksic Phd, Mph, L. Morgan Snell Mpp, Andrew J. Barnes Phd

Journal of Applied Research on Children: Informing Policy for Children at Risk

Background: E-cigarettes (EC) are the most commonly used tobacco product among youth. Additionally, youth EC users are progressing to smoking conventional cigarettes (CC). Although known to target youth, there are no current restrictions in the US on EC marketing, including advertising. The purpose of this study is to evaluate the relationship between EC advertisements and youth EC and CC use behaviors.

Methods: This study analyzed data from youth (12-17 years) aware of EC in Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health (PATH) study (n=12,199). Weighted logistic regression models assessed whether exposure and receptivity to any of …

A Comparison Of Sociodemographic Correlates Of Cigarette, Alcohol, And Energy Drink Consumption Among High School Students In The United States, 2010-2015, Eun Me Cha, Nalini Ranjit, Deanna M. Hoelscher

Journal of Applied Research on Children: Informing Policy for Children at Risk

OBJECTIVE: Despite growing awareness about the harmful physiological effects of energy drinks, especially among young people, there is little regulation governing the marketing and sale of these products to adolescents. Thus, in contrast to substances such as cigarettes and alcohol, energy drinks are readily available to adolescents, and widely consumed. It is not known if the easy availability of energy drinks has the effect of increasing usage of these substances among adolescents, and reducing sociodemographic differences in the consumption of energy drinks. In this study, we use pooled data (2010-2015) from the nationally representative Monitoring the Future survey (n=43,283), to …

Long-Term Exposure Of Fine Particulate Matter Causes Hypertension By Impaired Renal D1 Receptor-Mediated Sodium Excretion Via Upregulation Of G-Protein-Coupled Receptor Kinase Type 4 Expression In Sprague-Dawley Rats., Xi Lu, Zhengmeng Ye, Shuo Zheng, Hongmei Ren, Jing Zeng, Xinquan Wang, Pedro A Jose, Ken Chen, Chunyu Zeng

Medicine Faculty Publications

BACKGROUND: Epidemiological evidence supports an important association between air pollution exposure and hypertension. However, the mechanisms are not clear.

METHODS AND RESULTS: Our present study found that long-term exposure to fine particulate matter (PM2.5) causes hypertension and impairs renal sodium excretion, which might be ascribed to lower D1 receptor expression and higher D1 receptor phosphorylation, accompanied with a higher G-protein-coupled receptor kinase type 4 (GRK4) expression. The in vivo results were confirmed in in vitro studies (ie, PM2.5 increased basal and decreased D1 receptor mediated inhibitory effect on Na+-K+ ATPase activity, decreased D1 receptor expression, and increased D1 receptor phosphorylation …

January 2018 (Issue 1) : G6pd Deficiency, Aga Khan University Hospital, Karachi

Nutrition and Food Services Department (NFSD) Archives

• What happens in G6PD deficiency?
• Symptoms of G6PD Deficiency
• Role of Nutrition in G6PD Deficiency

An Evaluation Of The Groundwater Microbial Community's Toluene Biogenesis Potential At A Site In Southeast Louisiana, Michael A. Griffin Jr.

LSU Master's Theses

The broad goal of the research described in this thesis was to better understand the potential for biological toluene production to occur in groundwater at a Superfund Site located in southeast Louisiana. Previous literature reported that bacterial isolates under laboratory test conditions and undefined microbial communities in anaerobic sludge digesters and seasonally stratified lakes can produce toluene biogenically. Most of the research reported on this subject previously, however, has been on systems in Europe and little research has been reported previously on such phenomena in North America.

In the research described here, studies were conducted utilizing groundwater from a Superfund …

Fgf23 And Left Ventricular Hypertrophy In Children With Ckd., Mark M. Mitsnefes, Aisha Betoko, Michael F. Schneider, Isidro B. Salusky, Myles Selig Wolf, Harald Jüppner, Bradley A. Warady, Susan L. Furth, Anthony A. Portale

Manuscripts, Articles, Book Chapters and Other Papers

Background and objectives: High plasma concentration of fibroblast growth factor 23 (FGF23) is a risk factor for left ventricular hypertrophy (LVH) in adults with CKD, and induces myocardial hypertrophy in experimental CKD. We hypothesized that high FGF23 levels associate with a higher prevalence of LVH in children with CKD.

Design, setting, participants, & measurements: We performed echocardiograms and measured plasma C-terminal FGF23 concentrations in 587 children with mild-to-moderate CKD enrolled in the Chronic Kidney Disease in Children (CKiD) study. We used linear and logistic regression to analyze the association of plasma FGF23 with left ventricular mass index (LVMI) and LVH …

Sex And Age Differences In Trail Half Marathon Running, James W. Navalta, Jeffrey Montes, Elizabeth A. Tanner, Nathaniel Bodell, John C. Young

International Journal of Exercise Science

International Journal of Exercise Science 11(6): 281-289, 2018. Female participation is growing in trail running races. The purpose was to evaluate sex and age differences in top finishers of a trail running half marathon. Velocity differences between males (M) and females (F) were determined for the top 10 finishers of the Moab Trail Half Marathon from 2012 - 2015 across age, and by finishing place. Differences between age category and between sexes were determined through ANOVA with significance accepted at P < 0.05. A significant difference for running velocity was present between sexes at each age category (20-29 yr F = 2.9±0.3, M = 3.4±0.4 m·sec^-1; 30-39 yr F = 2.8±0.3, M = 3.3±0.3; 40-49 yr F = 2.7±0.3, M = 3.0±0.5; 50-59 …

Simulated Altitude Via Re-Breathing Creates Arterial Hypoxemia But Fails To Improve Elements Of Running Performance, Matthew J. Garver, Cory M. Scheadler, Logan M. Smith, Sarah J. Taylor, Chase M. Harbach

International Journal of Exercise Science

International Journal of Exercise Science 11(6): 187-197, 2018. Acclimatization to altitude has been shown to improve elements of performance. Use of simulated altitude is popular among athletes across the sports spectrum. This work was on a handheld, re-breathing device touted to enhance performance. Seven recreationally-trained athletes used the device for 18 hours over the course of the 37-day intervention trial. The elevations simulated were progressively increased from 1,524m to 6,096m. To ascertain potential efficacy, four performance trials were included (familiarization, baseline, and 2 follow-ups). Hematological (hematocrit, hemoglobin, and lactate), physiological (respiratory exchange ratio, heart rate, and oxygen consumption), and perceptual …

A Cross-Training Program Does Not Alter Self-Reported Physical Activity Levels In Elementary School Children, Melody L. White, Matthew S. Renfrow, Richard S. Farley, Dana K. Fuller, Brandi M. Eveland-Sayers, Jennifer L. Caputo

International Journal of Exercise Science

International Journal of Exercise Science 11(5): 308-318, 2018. The purpose of the study was to examine the effects of a school-based cross-training program on body mass index (BMI), attitudes toward physical activity (ATPA), and physical activity (PA) levels of children in the 4^th and 5^th grades. Children (N = 118) were divided into control (n = 60) and experimental (n = 58) groups based on class availability. While the control group continued academic classes as usual, the experimental group participated in cross-training involving resistance training (RT), calisthenics, and stretching twice a week for 10 weeks. …

Acute Specific Effects Of Caffeine-Containing Energy Drink On Different Physical Performances In Resistance-Trained Men, Camilla Astley, Diego Souza, Marcos Polito

International Journal of Exercise Science

International Journal of Exercise Science 11(4): 260-268, 2018. Caffeine containing energy drink (ED) is frequently used as ergogenic aid, but its effect on performance need more investigation. Thus, the aim of this study was to analyze the effects of acute ingestion of an ED on the physical performance of resistance-trained men subjected to successive tests in the same experimental protocol. Fifteen resistance-trained males (21.0 ± 0.3 yrs; 177.4 ± 1.8 cm; 79.6 ± 1.8 kg) ingested 2.5 mg caffeine per kg of body weight (619.5 ± 14.6 mL of ED) or a placebo in a double-blind randomized cross-over design. Physical …

Thirty-Year Trends Of Study Design And Statistics In Applied Sports And Exercise Biomechanics Research, George Vagenas, Dimitria Palaiothodorou, Duane Knudson

International Journal of Exercise Science

International Journal of Exercise Science 11(1): 239-259, 2018. This study documented the change in study design and statistics employed in applied sports and exercise biomechanics research from 1985 to 2014. The sample comprised 676 data based original research reports published in the Journal of Applied Biomechanics (JAB) from 1985 to 2014. Eight design and 10 statistical criteria were extracted from each study. Descriptive statistics were calculated and change in study criteria over time were documented. Design criteria that did not change over time, remaining at relatively low levels of rigor, were widespread (71%) use of small (2-20) sample sizes and …

Effects Of Single-Dose Dietary Nitrate On Oxygen Consumption During And After Maximal And Submaximal Exercise In Healthy Humans, Genevieve M. Kocoloski, Anne R. Crecelius

International Journal of Exercise Science

International Journal of Exercise Science 11(3): 214-225, 2018. Dietary nitrate (NO₃^-) has been shown to reduce oxygen consumption (VO₂) during moderate to high-intensity (e.g. time to fatigue, time trials) exercise and often in trained athletes. However, less is known regarding prolonged exercise and the potential impact of NO₃^- on post-exercise excess oxygen consumption (EPOC), particularly in untrained individuals, who may have different metabolic goals during exercise than trained individuals. We tested the hypothesis that acute nitrate supplementation in the form of beet root juice will significantly decrease both VO₂ during maximal exercise …

Physical Therapy Considerations For Chronic Kidney Disease And Secondary Sarcopenia, Michael O. Harris-Love, Haniel J. Hernandez, Gideon Obamwonyi

Exercise and Nutrition Sciences Faculty Publications

Chronic kidney disease (CKD) is a progressive condition that may negatively affect musculoskeletal health. These comorbidities may include malnutrition, osteoporosis, and decreased lean body mass. Secondary sarcopenia due to CKD may be associated with mobility limitations and elevated fall risk. Physical therapists are well-positioned among the health care team to screen for secondary sarcopenia in those with CKD and for the treatment of musculoskeletal comorbid conditions that may affect functional performance. Given the consequences of both low muscle mass and low bone mineral density, appropriate and timely physical therapy is important for fall risk assessment and intervention to minimize the …

The Application Of An Implementation Science Framework To Comprehensive School Physical Activity Programs: Be A Champion!, Justin B. Moore, Russell L. Carson, Collin A. Webster, Camelia Renee Singletary, Darla M. Castelli, Russell R. Pate, Michael W. Beets, Aaron Beighle

Faculty Publications

Comprehensive school physical activity programs (CSPAPs) have been endorsed as a promising strategy to increase youth physical activity (PA) in school settings. A CSPAP is a five-component approach, which includes opportunities before, during, and after school for PA. Extensive resources are available to public health practitioners and school officials regarding what should be implemented, but little guidance and few resources are available regarding how to effectively implement a CSPAP. Implementation science provides a number of conceptual frameworks that can guide implementation of a CSPAP, but few published studies have employed an implementation science framework to a CSPAP. Therefore, we developed …

Nextgen Voices: Research Resolutions, Felicia Olmeta-Schult, Lauren Massa Segal, Sam Tyner, Twila Alexandra Moon, Ryan Dz Wei Chow, Prosanta Chakrabarty, Martin Pacesa, Anna Igorevna Podgornaia, Jennifer Chen, Bipin Singh, Bo Cao, Rishi Raj Singh Sidhu, Bryce W.Q. Tan, Prashant Sood, Stuart Parker, Matthew A. Scult, Desiree Van Haute, Nikos Konstantinides, Beat A. Schwendimann, Sudhakar Srivastava, Raffaele Fiorenza, Ken Dutton-Regester, Rachel Hale, Emre Ozan Polat, Edward Lau, Audrey L. Mayer, Easton R. White

Faculty Publications

No abstract provided.