Campus Assembly Minutes 10/30/2018, Campus Assembly

Campus Assembly

No abstract provided.

Ua12/2/1 College Heights Herald, Vol. 94, No. 9 [10], Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Voter Guide – Patti Minter, Benjamin Lawson
• DeLetter, Emily. Construction of First-year Village Slated to Begin – Housing & Residence Life
• Austin, Emma. Will Local Voters Make Warren County Wet? – Alcohol
• Austin, Emma. Fraternity Member Brings Firearm to Float Site – Delta Tau Delta / Chi Omega
• Dobbs, Jack. Kentucky Museum Hosts Celebration of WKU Professors – Jim Wayne Miller, Mary Ellen Miller
• DeLetter, Emily. WKU to Host Annual International Education Week
• DeLetter, Emily. Kentucky Museum to Establish Youth Scholarship
• DeBerry, Kierra. Organizations Provide …

The Indiana Statesman, October 30, 2018, Indiana State University

Student Newspaper

Indiana State crowns new Miss ISU; Stand Against Hate Vigil; HLA sponsors Taste of Mexico; Downtown Haunted Haute creates community ties

The Prospector, October 30, 2018, Utep Student Publications

The Prospector

Headline: Halloween Issue: Dia de los Muertos

Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements For Nad+ Synthesis, Laura Palzer, Jessica J. Bader, Frances Angel, Megan Witzel, Sydney Blaser, Alexis Mcneil, Miles K. Wandersee, N. Adrian Leu, Christopher J. Lengner, Clara E. Cho, Kevin D. Welch, James B. Kirkland, Ralph G. Meyer, Mirella L. Meyer-Ficca

Animal, Dairy, and Veterinary Science Faculty Publications

NAD⁺ is essential for redox reactions in energy metabolism and necessary for DNA repair and epigenetic modification. Humans require sufficient amounts of dietary niacin (nicotinic acid, nicotinamide, and nicotinamide riboside) for adequate NAD⁺ synthesis. In contrast, mice easily generate sufficient NAD⁺ solely from tryptophan through the kynurenine pathway. We show that transgenic mice with inducible expression of human alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase (ACMSD) become niacin dependent similar to humans when ACMSD expression is high. On niacin-free diets, these acquired niacin dependency (ANDY) mice developed reversible, mild-to-severe NAD⁺ deficiency, depending on the nutrient composition of the diet. NAD deficiency …

Invasion Of The P Elements: Tolerance Is Not Futile, Colin D. Meiklejohn, Justin P. Blumenstiel

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Organisms are locked in an eternal struggle with parasitic DNA sequences that live inside their genomes and wreak havoc on their host’s chromosomes as they spread through populations. To combat these parasites, host species have evolved elaborate mechanisms of resistance that suppress their activity. A new study in Drosophila indicates that, prior to the acquisition of resistance, individuals can vary in their ability to tolerate the activity of these genomic parasites, ignoring or repairing the damage they induce. This tolerance results from variation at genes involved in germline development and DNA damage checkpoints and suggests that these highly conserved cellular …

Highly Potent 1h-1,2,3-Triazole-Tethered Isatin-Metronidazole Conjugates Against Anaerobic Foodborne, Waterborne, And Sexually-Transmitted Protozoal Parasites, Sumit Kumar, Trpta Bains, Ashley Sae Won Kim, Christina Tam, Jong Kim, Luisa W. Cheng, Kirkwood M. Land, Anjan Debnath, Vipan Kumar

College of the Pacific Faculty Articles

Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in tropical and subtropical regions of the world. Metronidazole (MTZ) is the current drug of choice for amebiasis, giardiasis, and trichomoniasis but it has several adverse effects and potential resistance is a concern. In order to develop alternative antimicrobials, a library of 1H-1,2,3-triazole-tethered metronidazole-isatin conjugates was synthesized using Huisgen's azide-alkyne cycloaddition reaction and evaluated for their amebicidal, anti-trichomonal, and anti-giardial potential. Most of the synthesized conjugates exhibited activities against Trichomonas vaginalis, Tritrichomonas foetus, Entamoeba histolytica, and Giardia lamblia. While activities against T. vaginalis and T. foetus were comparable to …

A Neural Network Based Model Effectively Predicts Enhancers From Clinical Atac-Seq Samples., Asa Thibodeau, Asli Uyar, Shubham Khetan, Michael L. Stitzel, Duygu Ucar

Faculty Research 2018

Enhancers are cis-acting sequences that regulate transcription rates of their target genes in a cell-specific manner and harbor disease-associated sequence variants in cognate cell types. Many complex diseases are associated with enhancer malfunction, necessitating the discovery and study of enhancers from clinical samples. Assay for Transposase Accessible Chromatin (ATAC-seq) technology can interrogate chromatin accessibility from small cell numbers and facilitate studying enhancers in pathologies. However, on average, ~35% of open chromatin regions (OCRs) from ATAC-seq samples map to enhancers. We developed a neural network-based model, Predicting Enhancers from ATAC-Seq data (PEAS), to effectively infer enhancers from clinical ATAC-seq samples by …

2018-October-30-Slow Road To Healing, University Marketing And Communication, East Tennessee State University

ETSU News

‘Slow Road to Healing’

JOHNSON CITY (Oct. 30, 2018) – “Slow Road to Healing” is the topic of a talk to be delivered by Dr. Victoria Sweet on Thursday, Nov. 1, at 6 p.m. in the Grand Soldiers Ballroom at the Carnegie Hotel on State of Franklin Road.

Sweet is a physician, Guggenheim Fellow of Medical History and author of two books, “God’s Hotel: A Doctor, a Hospital, and a Pilgrimage to the Heart of Medicine” and “Slow Medicine: The Way to Healing.”

Her free public talk, which will focus on the “slow medicine movement,” or “spending time to save …

The Current Volume 29 : Issue 12, Nova Southeastern University

Student Newspapers

No abstract provided.

Development Of The Global Engineering Programming Model: A Participatory, Mixed-Methods Approach, Scott C. Streiner, Mary Elizabeth Besterfield-Sacre

Journal of International Engineering Education

Over the past few decades, higher education institutions have emphasized global education as a core aspect of their strategic goals, yet a gap exists in implementation at the school level, particularly in engineering. As engineering schools invest in internationalizing their programs, research is needed regarding key strategic areas and their relationship to sustained programming efforts. This study uses a participatory, integrative mixed-methods approach to develop an operational framework for global strategies, policies, and programs. A thematic, qualitative analysis of semi-structured interviews followed by a group concept mapping activity was conducted with directors of study abroad and vice provosts of global …

Forecast Or Fall: Prediction's Importance To Postural Control, Chris J. Dakin, David A.E. Bolton

Kinesiology and Health Science Faculty Publications

To interact successfully with an uncertain environment, organisms must be able to respond to both unanticipated and anticipated events. For unanticipated events, organisms have evolved stereotyped motor behaviors mapped to the statistical regularities of the environment, which can be trigged by specific sensory stimuli. These 'reflexive' responses are more or less hardwired to prevent falls and represent, maybe, the best available solution to maintaining posture given limited available time and information. With the gift of foresight, however, motor behaviors can be tuned or prepared in advance, improving the ability of the organism to compensate for, and interact with, the changing …

Analysis Of Particle Behavior Inside The Classifier Of A Raymond Bowl Mill While Co-Milling Woody Biomass With Coal, Seyedhassan Fakourian, Andrew R. Fry, Tanner Jasperson

Faculty Publications

Woody biomass cofiring with coal at existing pulverized-coal boilers is known to be a green energy source and is a low-expense alternative for pure coal combustion. Co-milling woody biomass particles (15 wt%) with coal particles (85 wt%) before burning at a boiler is a complex problem because large woody biomass particles (>300 μm) exit the milling system along with the fine particles. A Computational Particle Fluid Dynamics (CPFD) is used in this paper to present a novel analysis about the behavior of woody biomass particles as they are mixed with coal particles inside the classifier. To meet this …

Predominance Of Triple Wild-Type And Igf2r Mutations In Mucosal Melanomas., Yuuki Iida, Matthew P Salomon, Keisuke Hata, Kevin Tran, Shuichi Ohe, Chester Griffiths, Sandy C Hsu, Nellie Nelson, Dave S B Hoon

Articles, Abstracts, and Reports

BACKGROUND: Primary mucosal melanoma (MM) is a rare subtype of melanoma that arises from melanocytes in the mucosa. MM has not been well profiled for mutations and its etiology is not well understood, rendering current treatment strategies unsuccessful. Hence, we investigated mutational landscape for MM to understand its etiology and to clarify mutations that are potentially relevant for MM treatment.

METHODS: Forty one MM and 48 cutaneous melanoma (CM) tissues were profiled for mutations using targeted deep next-generation sequencing (NGS) for 89 cancer-related genes. A total of 997 mutations within exons were analyzed for their mutational spectrum and prevalence of …

After Life: Governmental Interests And The New Antiabortion Incrementalism, Mary Ziegler

University of Miami Law Review

In the aftermath of the Supreme Court’s decision in Whole Woman’s Health v. Hellerstedt, commentators have focused on the effect of antiabortion restrictions. But as this Article shows, Whole Woman’s Health is part of the story of an equally important tactic used by those chipping away at abortion rights: the recognition of new governmental interests justifying abortion regulations. Using original archival research, this Article traces the rise of this strategy and documents its influence on Supreme Court doctrine, making sense of what seem to be contradictory rulings on abortion.

How should courts deal with novel legislative purposes or broader …

Quality Improvement In Neurology: Epilepsy Quality Measurement Set 2017 Update, Anup D. Patel, Christine Baca, Gary Franklin, Susan T. Herman, Inna Hughes, Lisa Meunier, Lidia Mvr Moura, Heidi Munger Clary, Brandy Parker-Mcfadden, Mary Jo Pugh, Rebecca J. Schultz, Marianna V. Spanaki, Amy Bennett, S A. Josephson

Neurology Articles

No abstract provided.

Dan Curran: Grateful For The Gift Of Life, University Of Dayton

News Releases

In a hilarious moment at a celebration dinner on campus more than two years ago, outgoing University of Dayton president Dan Curran poked fun at himself when he discovered a disturbing fact while perusing the wall of presidential portraits in St. Mary’s Hall.

Lindenwood Digest, October 30, 2018, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

The Impact Of Disease-Modifying Therapy Access Barriers On People With Multiple Sclerosis: Mixed-Methods Study., Kristina F. Simacek, John J. Ko, Debbie Moreton, Stefan Varga, Kristen Johnson, Bozena J. Katic

College of Population Health Faculty Papers

BACKGROUND: In the United States, people with relapsing-remitting multiple sclerosis (RRMS) can face difficulty accessing disease-modifying therapies (DMTs) because of insurance, pharmacy, or provider policies. These barriers have been associated with poor adherence and negative health outcomes.

OBJECTIVE: The goals of this study were to describe the overall occurrence of difficulties and delays associated with gaining access to DMTs among people with RRMS, to assess DMT adherence during periods of reduced access, and to contextualize the patients' journey from receipt of a prescription for DMT to obtaining and taking their medication when faced with access barriers.

METHODS: We recruited US-based …

California Island Rediscovery: Building An Archive To Improve Conservation Today And Equip The Historical Ecologist Of Tomorrow, Scott A. Morrison, T. Scott Sillett, W. Chris Funk, Cameron K. Ghalambor, Torben C. Rick

Western North American Naturalist

An understanding of how past conditions have shaped present-day ecological patterns and trends is critical to science-based conservation management. Unfortunately, the records, specimens, and objects historical ecologists need to help generate that understanding are often lacking. And because of a general underinvestment by society in systematic collection and museum curation, future historical ecologists may be similarly limited in their ability to investigate conditions regarding our present day. Given the importance of historical data and materials in contemporary conservation decision-making, we suggest it is incumbent upon resource managers and scientists to ask whether additional research efforts are needed to document past …

Assessing The Resilience Of Human Systems: A Critical Evaluation Of Universal And Contextual Resilience Variables, O Wilson, G Wilson

School of Geography, Earth and Environmental Sciences

This study analyses the use of contextual and universal variables to assess the resilience of human systems. The article examines the terms ‘contextual’ and ‘universal’ in relation to resilience variables, how widely accepted different variables are as indicators of resilience, and the extent to which variables can be classified using these conceptual terms. The article analyses how the ‘direction’ of a variable indicating either resilience or vulnerability can be assessed and argues that often the same variable can be interpreted differently for the resilience of a human system, depending on the context of the system under investigation and the positionality …

Supporting First-Generation Students’ Adjustment To College With High-Impact Practices, Theresa Conefrey

English

This qualitative case study describes some of the issues faced by incoming first-generation college students at a private, 4-year institution in the northwest. Using constructs drawn from social cognitive theory and social cognitive career theory, it explores how high-impact practices such as learning communities, writing-intensive courses, and ePortfolios might impact first-generation students’ adjustment during their first year of college. The findings of the research on students’ writing in their first-year composition course suggest that the cumulative impact of engaging in multiple high-impact practices improves students’ literacy and study skills. In addition, these educational practices appear to increase students’ self-appraisal of …

Innovation In Pedagogy And Technology Symposium: University Of Nebraska, May 8, 2018, University Of Nebraska

Zea E-Books Collection

Selected Conference Proceedings, Presented by University of Nebraska Online and University of Nebraska Information Technology Services.

University of Nebraska Information Technology Services (NU ITS) and University of Nebraska Online (NU Online) present an education and technology symposium each spring. The Innovation in Pedagogy and Technology Symposium provides University of Nebraska (NU) faculty and staff the opportunity to learn from nationally recognized experts, share their experiences and learn from the initiatives of colleagues from across the system. This event is offered free to NU administrators, faculty and staff free of charge. Tuesday, May 8, 2018 The Cornhusker Marriott, Lincoln, NE

Technology …

Gender And Schizophrenia, University Of Dayton

News Releases

New research from University of Dayton psychologist Julie Walsh-Messinger and Icahn School of Medicine at Mount Sinai psychiatrist Dolores Malaspina uncovers key differences in the brains of men and women suffering from schizophrenia.

The Usda Summer Food Service Program In Coos County New Hampshire, Jean Bessette

Carsey Publications

In this report, author Jean Bessette examines the U.S. Department of Agriculture (USDA) Summer Food Service Program (SFSP) operating in 2017 in four communities in Coös County, New Hampshire. She reports that the SFSP provides benefits to Coös County on multiple levels. For children, it ensures the availability of nutritious meals in the summer when school meal programs are not operating; for parents, it helps to alleviate pressure on food budgets; and for communities, it helps to ameliorate the impacts of poverty and lack of economic growth and development. Successful strategies to increase participation in summer food programs include providing …

Academic Senate - Meeting Minutes, 10/30/2018, Academic Senate

Academic Senate Minutes

No abstract provided.

Academic Senate - Agenda, 10/30/2018, Academic Senate

Academic Senate Agendas

No abstract provided.

Ground-Truthing Social Vulnerability Indices Of Alaska Fishing Communities, Anna Lavoie, Kim Sparks, Stephen Kasperski, Amber Himes-Cornell, Kristin Hoelting, Conor Maguire

All Faculty Scholarship for the College of the Sciences

Community vulnerability is increasingly evaluated through quantitative social indices, typically developed using secondary data sources rather than primary data collection. It is necessary to understand the validity of these indices if they will be used to inform policy and decision making. This paper presents a ground-truthing effort to validate quantitative indices that characterize the well-being of Alaska fishing communities. We utilized ethnographic data collected from 13 representative communities and a capital assets framework to ground-truth the indices, in which qualitative ranks of vulnerability were compared against quantitative indices. The majority (73.8%) of ranks were in complete or moderate agreement and …

Computational Models Exploring The Role Of Flexibility In Binding Tat Peptide To Tar Rna, Thanh Quoc Le

Master's Theses

Viral-encoded regulatory proteins interacting with RNA target sequences control the gene expression of lentiviruses, notably the human immunodeficiency virus (HIV) and bovine immunodeficiency virus (BIV). The latter provides a simpler interaction model between the viral trans-activator protein (Tat) and trans-activation response RNA element (TAR), including Tat peptides binding to TAR RNA fragments. This model may offer insights into clinical approaches for treatment, initially through theoretical consideration of the role of peptide flexibility in binding as evidenced by literature-based binding assays and NMR. It has more recently been suggested that DNA-protein binding may also be enhanced by increases in conformational entropy. …

Characterization Of Four Type-C Silica Columns Using Resveratrol Analogues, Joshua Topete

Master's Theses

High performance liquid chromatography (HPLC) is an analytical technique used to separate, identify and quantify components in a solution based on the affinities between analyte, mobile phase and stationary phase. The main goal of my research is to characterize four Type-C silica columns by comparing the retention of resveratrol analogues. The four columns included are functionalized with either Diamond Bidentate C18 (DBC18), Bidentate C18 (BC18), phenyl hydride or diol groups. Retention maps displaying mobile phase composition compared to compound retention times were compared between columns. In addition to this, two organic solvents (acetonitrile and methanol) were compared. Considering that the …