Digital Commons Network^™

Trends In Opioid Use In Pediatric Patients In Us Emergency Departments From 2006 To 2015, Daniel M. Tomaszewski, Cody Arbuckle, Sun Yang, Erik J. Linstead

Pharmacy Faculty Articles and Research

Importance The use of opioids to treat pain in pediatric patients has been viewed as necessary; however, this practice has raised concerns regarding opioid abuse and the effects of opioid use. To effectively adjust policy regarding opioids in the pediatric population, prescribing patterns must be better understood.

Objective To evaluate opioid prescribing patterns in US pediatric patients and factors associated with opioid prescribing.

Design, Setting, and Participants This cross-sectional study used publicly available data from the National Hospital Ambulatory Medical Care Survey from January 1, 2006, to December 31, 2015. Analysis included the use of bivariate and multivariate models to …

Dwivedi Named To National Suicide Prevention Organization Board, Staff

Browse All News

No abstract provided.

Targeted Re-Instruction For Hearing Aid Use And Care Skills, Carly Catherine Alicea

Dissertations - ALL

Purpose: Approximately 30% of hearing aid owners do not wear their hearing aids. One of the main reasons reported for hearing aid non-use is that hearing aid owners cannot successfully use and/or care for their hearing aids (Lupsakko, Kautiainen, & Sulkava 2005; Popelka et al. 1998; Vuorialho, Karinen, & Sorri 2006). The primary purpose of the present study was to evaluate the benefit of identifying specific hearing aid use and care skills that a hearing aid user cannot perform or has difficulty performing and providing re-instruction on those specific skills. This is operationally defined in the present study as targeted …

Lemons Into Lemonade: Black Undergraduate Women's Embodiment Of Strength And Resilience At A Pwi, Jordan Shelby West

Dissertations - ALL

This dissertation is a qualitative research project for Black undergraduate women and about Black undergraduate women. The aim of this dissertation is to lift, center, and share the lived experiences of Black undergraduate women as they reflect on the messages and memories of coming into their Blackness, their transition to and experiences while attending a PWI, and the ways in which they continue to make meaning of space. Informed by Black Feminist Theory and Critical Race Theory, the framework and methods used in this project prioritize the care of the participants and allow them to be co-creators of their own …

In Re Board Of Tax Appeals, Appeal No. 16-A-1079 Appellant's Brief Dckt. 46191

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Report Of The N|150 Commission, Donde Ashmos Plowman, William G. Thomas Iii

University of Nebraska-Lincoln Administration: Reports, Papers, Publications, and Presentations

As the campus prepares to mark its 150th year, the University of Nebraska–Lincoln is poised to chart a bold and distinctive course for the next generation. UNL Chancellor Ronnie Green appointed more than 150 stakeholders of the university – faculty, staff, students, alumni, and community members – to the Nebraska Commission of 150 to envision how the university can best serve Nebraska and the world for the next 25 years.

The university’s inaugural charter in 1869 as a land-grant institution offered a sweeping vision for our founding:

To afford the inhabitants of this state with the means of acquiring a …

Reappraisal Of The Toxicity Test Method Using The Green Alga Ulva Pertusa Kjellman (Chlorophyta),, Mt Brown

School of Biological and Marine Sciences

This study was aimed to develop an objective way of quantifying the reproductive status of the green macroalga, Ulva pertusa using a vital stain and programmed automated analysis (by Image J program). The EC50 values (with 95% CI), the concentrations of toxicants inducing a reduction of 50% in sporulation after 96 h exposure, from the newly developed method were similar to those obtained by the conventional method: 0.651 (0.598–0.705) mg l-1 for Cd, 0.144 (0.110–0.162) mg l-1 for Cu, 0.180 (0.165–0.195) mg l-1 for atrazine, 0.076 (0.049–0.094) mg l-1 for diuron and 30.6 (26.5–34.4) ml l-1 for DMSO, respectively. When …

Health Equity Through Spatial Justice: A Critical Phenomenology Of Urban Trail Makers, Arvin Simon

Electronic Theses and Dissertations

Research has increasingly demonstrated that race, class and place are powerful predictors of health and social justice. This study was conducted to identify the lived experiences of individuals who were hired and trained as part of a green job program that created trails within a city park in Pittsburgh’s Mount Washington Community. This program has historically hired individuals who were formerly incarcerated, many of whom identify as African American. We explored the personal and social experiences of working in nature to better appreciate the intersections of race, class and environment in an urban community. This current study is based on …

Characterization Of G-Protein Coupled Receptors In Pain, Depression And Anxiety, Neil Lax

Electronic Theses and Dissertations

Chronic pain and major depressive disorder are widespread conditions in the world. Interestingly, these conditions often occur comorbidly, with each individual disease amplifying the symptoms of the other. A significant amount of preclinical research in pain and depression focuses on G-protein coupled receptors (GPCRs), implying that GPCRs may be useful in treating this comorbidity. Our efforts have sought to characterize several poorly understood GPCRs, including the serotonin receptor subtypes 2C and 7 (5-HT2CR and 5-HT7R) and metabotropic glutamate receptor 5 (mGluR5), along with more well-known GPCRs such as the mu opioid receptor (MOR), and the role that they play in …

Synthesis Of Novel 6-Substituted And 5-Substituted Pyrrolo[2,3-D] Pyrimidine Antifolates As Targeted Anticancer Therapies, Xinxin Li

Electronic Theses and Dissertations

The dissertation will give an introduction, background and current research progress in the areas of antifolates and chemotherapy of anticancer. The design and synthesis of classical 6- substituted pyrrolo[2,3-d]pyrimidines and 5-substituted pyrrolo[2,3-d]pyrimidines as potential antifolates have been described. The design variations include: methylated thiophene regioisomers, fluorinated phenyl regioisomers, thionyl regioisomers on the side chain of pyrrolo[2,3-d]pyrimidines. As a part of this study, a series of new compounds have been synthesized and characterized. Of these, ten final compounds were submitted for biological evaluation.

The Influence Of Age, Gender, And Thiol Repletion In An In Vivo Model Of Lewy Body Disorders, Daniel Mason

Electronic Theses and Dissertations

Lewy body disorders are a family of neurological brain disorders associated with olfactory, motor, and cognitive deficits and are collectively defined as α-synucleinopathies, as they are characterized by hallmark “Lewy bodies” composed of aggregated, fibrillar α-synuclein. It is not certain but often posited that fibrillar α-synuclein seeds the progressive, self-propagating spread of Lewy pathology through neuroanatomical circuitry. Furthermore, the site of disease induction is still debated. In Aim I, we developed a novel protocol for generating reproducible and robust α-synucleinopathy in the limbic temporal lobe following infusions of preformed α-synuclein iv fibrils into the mouse olfactory bulb, which is frequently …

Identity Negotiation, Saudi Women, And The Impact Of The 2011 Royal Decree: An Investigation Of The Cultural, Religious, And Societal Shifts Among Women In The Saudi Arabian Public Sphere, Maha Alshoaibi

Electronic Theses and Dissertations

Historically, Saudi Arabian culture has been deeply rooted in tradition, religious customs, family-oriented structures, and gender derived expectations for men and women alike. Saudi Arabian culture emphasizes a patriarchal family structure where men financially provide for their family whereas women are expected to manage internal household duties such as raising children, upholding household affairs, and working within a limited scope of employment. The concept of Saudi Arabian women integrating into the public workforce has been a source of contention and debate for the last several hundred years. Due to recent changes in political and economic events, a royal decree issued …

A Qualitative Inquiry Into The Systemic Influences Upon The Wellness Of Home And Community Based Counselor, Elizabeth Moore

Electronic Theses and Dissertations

Home and community based counseling services have become instrumental to the treatment of children and adolescents struggling with mental illness. Counselors working in these systems of care face significant challenges in this unique setting. Most home and community based counselors (HCBCs) face these challenges as recent graduates, not having adequate preparation for the home setting, while receiving little supervision. HCBCs have reported feeling isolated and unsupported and question their effectiveness as counselors. Macchi, Johnson, and Durtschi’s (2014) results point to the importance of self-care to HCBC wellness, especially when the HCBC is lacking supervision. Yet, we are unable to glean …

An Exploratory Survey Of Factors Affecting Satisfaction With Educational Experiences For Parents Of Children With Cystic Fibrosis, Rebecca Perry Keenan

Electronic Theses and Dissertations

Consumer satisfaction has been studied extensively as it relates to service seeking behavior, positive perceptions of services rendered, and measurable benefit as a result of service delivery. Furthermore, numerous studies have explored the importance of a strong, collaborative home-school partnership for student success. Additionally, previous research has identified children with chronic illnesses as a special population frequently requiring individualized accommodations and modifications to promote success in the educational environment, and therefore testing the limits of the educational system to adequately meet their needs. Finally, research has described the common sequelae of Cystic Fibrosis, including wide-ranging physical, behavioral, and functional consequences. …

Tumble Tots: Outcomes Of A Gymnastics Program For Children With Disabilities, Cayla Leichtenberger

Electronic Theses and Dissertations

Despite the benefits, children with disabilities do not participate in recreational activities as often as typically developing peers. The purpose of the program was to: 1) describe the benefit of a gymnastics program on a child’s development, and 2) identify the impact of a staff training program. Engagement in the proposed program aimed to ultimately contribute to a child’s involvement in recreational activities, health and quality of life (QOL). All participants in the gymnastics program demonstrated a positive change in motor and communication skills. Pre-test data from the staff training program indicated that none of the gymnastics staff members were …

Bullying Of Linguistically Diverse Learners: Results From The Youth Risk Behavior Survey, Jenna Woodarek

Electronic Theses and Dissertations

Bullying is a serious phenomenon yielding significant consequences for youth who are victimized, often targeted due to their perceived level of difference from their peers. This “otherness” can often be amplified in minoritized populations, especially those which have multiple, cooccurring vulnerabilities to be targets of bullying. After a period of bullying rates decreasing in the US, special interest group inquiries found bullying rates to be on the rise again and reportedly motivated by ethnicity or race, immigrant status, and proficiency in the English language. The present research study aims to expand upon the existing pertinent literature base specific to the …

Sensory-Based Programming In Mental Health: Sense Of Self, Nikki Yeckel

Electronic Theses and Dissertations

The doctoral experiential component (DEC) for this Capstone was completed at the Veterans Affairs Healthcare System (VA) in Pittsburgh, Pennsylvania. The program, called Sense of Self, was implemented with the Veteran mental health (MH) population in an inpatient psychiatric rehabilitation unit at the VA. Sense of Self was a three-day educational program that educated Veterans on the sensory systems and sensory processing, provided calming or alerting strategies with use of sensory materials, and assisted the Veterans in creating sensory home programs based on personal goals. The goals of this Capstone were to inform the staff of the Veteran demographic population …

Externality In Hegel's Philosophy Of Nature, Martin Krahn

Electronic Theses and Dissertations

The topic of my dissertation is the metaphysics of laws of nature in Hegel’s philosophy of nature. I argue that Hegel differentiates laws of nature from norms of culture through a concept of “externality,” according to which the universals or laws of nature stand outside of, apart from, independent from their particulars. He contrasts this with norms of culture, where the universals are internal to the particulars, such that in culture the particular events or actions shape the norms, whereas in nature, the laws remain the same through their independence from the particular events. I then address the consequences this …

Pyrrolo[2,3-D]Pyrimidine Classical Antifolates For Targeted Cancer Chemotherapy- Applications Of Bioisosteric And Regioisomeric Substitutions For Improved Tumor-Selectivity And Potency, Manasa Punaha Ravindra

Electronic Theses and Dissertations

In 2018, it is estimated that 1,735,350 new cases of cancer and 609,640 deaths from the disease will be diagnosed in the United States alone. Conventional chemotherapy is by far the most successful category of clinical oncology, having cured (complete remission (CR), without return) or provided clinical benefit to millions of people. However, since its earliest discovery, the major causes of failure of conventional cancer chemotherapy have been dose-limiting toxicities and development of resistance. There is a desperate ongoing search for new cancer therapies as tumor-targeted agents (without harming normal cells or tissues) with low propensity for the development of …

Self-Compassion And Cultural Values: A Cross-Cultural Study Of Self-Compassion Using A Multitrait-Multimethod (Mtmm) Analytical Procedure, Jesus Montero-Marin, Willem Kuyken, Catherine Crane, Jenny Gu, Ruth A. Baer, Aida A. Al-Awamleh, Satoshi Akutsu, Claudio Araya-Véliz, Nima Ghorbani, Zhuo Job Chen, Min-Sun Kim, Michail Mantzios, Danilo N. Rolim Dos Santos, Luiz C. Serramo López, Ahmed A. Teleb, P. J. Watson, Ayano Yamaguchi, Eunjoo Yang, Javier García-Campayo

Psychology Faculty Publications

Self-compassion is natural, trainable and multi-faceted human capacity. To date there has been little research into the role of culture in influencing the conceptual structure of the underlying construct, the relative importance of different facets of self-compassion, nor its relationships to cultural values. This study employed a cross-cultural design, with 4,124 participants from 11 purposively sampled datasets drawn from different countries. We aimed to assess the relevance of positive and negative items when building the self-compassion construct, the convergence among the self-compassion components, and the possible influence of cultural values. Each dataset comprised undergraduate students who completed the “Self-Compassion Scale” …

Regulation Of In Vivo Excitatory/Inhibitory Balance By The Cystine/Glutamate Exchanger System Xc-, Sheila Marie Shahidzadeh Sears

Dissertations - ALL

System xc- (Sxc-) is a cellular antiporter that links the import of L-cystine with the export of L-glutamate. In the central nervous system (CNS), this export contributes to the ambient glutamate levels found in the synaptic cleft. To wit, a 50% reduction in extracellular glutamate has been demonstrated in animals null for the substrate-specific light chain, xCT. Moreover, in most tissues, including the CNS, cystine import through Sxc- is necessary for the synthesis and maintenance of glutathione (GSH) levels. Given that either a reduction in ambient glutamate levels and/or a redox imbalance involving GSH have been reported to affect synaptic …

Village Doctors And Vulnerable Bodies: Gender, Medicine, And Risk In North India, Jocelyn Killmer

Dissertations - ALL

This dissertation tracks an uncommon migration: the movement of young women doctors from urban medical colleges to rural clinics in Rajasthan, North India. The ability for young women doctors to transfer their lives to a rural clinic, even for a year or two, is vital for career advancement in Rajasthan’s government health sector. Yet I found that women, over and over, rejected this opportunity, turning this urban to rural migration into a trickle rather than a flow. Through interviews, observations, and travel in urban and rural Jaipur district, I explore the meanings of urban and rural spaces as well as …

Identifying The Genetic Mechanisms In Seizure Threshold Regulation, Yifan Gong

Dissertations - ALL

Epilepsy is a brain disease defined by having recurrent and spontaneous seizures. The susceptibility to seizure is determined by seizure threshold, which describes the balance between excitatory and inhibitory neurotransmission in the brain. Epileptogenesis, the transition from normal brain to epileptic brain, is accompanied by a progressive reduction of seizure threshold and has been shown to have genetic influences. Expression of neuronal cyclooxygenase-2 (COX-2) gene, PTGS2, a primary gene that regulates prostaglandin synthesis in the normal brain, is enhanced by excitatory neurotransmission and is under tight regulation of N-Methyl-D-Aspartate type glutamate receptor (NMDAR) activity in cortical neurons. The 3’ untranslated …

Sex Differences In Cardiovascular Adaptations To Chronic Endurance Exercise, Jacqueline A. Augustine

Dissertations - ALL

Endurance exercise typically leads to beneficial cardiac adaptations manifested as increased cardiac mass, higher cardiac function and lower central hemodynamic load (blood pressure, aortic stiffness and wave reflections). However, studies in male marathoners suggest detrimental cardiac remodeling, such that larger cardiac mass is associated with reduced cardiac function and higher central hemodynamic load. There are well-established sex differences in cardiac adaptations to endurance exercise and central hemodynamics across the lifespan. Whether there are sex differences in cardiovascular adaptations in marathoners requires further scrutiny. We examined sex differences in 1) Left ventricle (LV) structure, 2) LV function 3) 24-hour central hemodynamic …

Photolysis Kinetics Of Aromatic Pollutants In Liquid And Solid Environmental Condensed Phases, Alexa Stathis

Dissertations - ALL

Condensed phases in the environment are often chemically complex. Reactivity can differ significantly depending on the physical state (i.e. solid or liquid) and composition. Many laboratory studies that investigate reaction kinetics in condensed phases are done under simplified conditions that do not accurately reflect the complexity found in the environment. I have measured photolysis rate constants of the aromatic pollutants toluene, ethylbenzene, xylenes (TEX) and anthracene under environmentally-relevant conditions in order to improve fate predictions. The photolysis kinetics of TEX in water, ice and at ice surfaces were investigated using environmentally-relevant wavelengths. Previously, photolysis has not been considered a viable …

The Effect Of Fetal Programming On Physical Activity Behaviors, Jessica Garay Redmond

Dissertations - ALL

Appropriate fetal growth and development largely depends on the health and nutritional status of the mother. Exposure to a stressful intra-uterine environment leads to a series of adjustments, known as fetal programming, which have both short- and long-term implications. Immediately, the growth and development of the fetus is altered, resulting in intra-uterine growth restriction and a small size at birth. Long-term, individuals who experience fetal programming are at higher risk of developing certain chronic diseases.

In the current study, we examined the relationship between size at birth (an indicator of intra-uterine growth restriction and thus, fetal programming) and two main …

A Christmas Reflection, Eric F. Spina

President's Blog: From the Heart

In my annual Christmas message to students, faculty, and staff, I reflect on how the University of Dayton is more than our home away from home. It's a place in our hearts.

The Effect Of Ipad Instruction On Capital Letter Recognition Of Preschoolers, Jessica Adkins

Dissertations, Theses, and Projects

The purpose of this study is to look at the effect of iPad instruction on capital letter recognition in preschool children between the ages of four and five. The study divided participants into two groups. One group received capital letter instruction with an iPad. The second group received capital letter instruction using letter manipulatives. Letter manipulatives were wooden puzzle letters. Baseline data was taken on capital letter recognition of all participants before this study began. At the end of the study, data was taken on capital letter recognition of all participants. Baseline and final data was compared to show growth. …

Take Charge For Therapy Discharge: Outcomes Of A Patient Education Program Applying The Co-Op Approach, Kathryn Westley

Electronic Theses and Dissertations

A thorough needs assessment at HealthSouth Rehabilitation Hospital of Largo revealed slight dissatisfaction scores on the Press Ganey survey for both the occupational therapy department and discharge planning processes. This quality improvement project, Take Charge for Therapy Discharge, implemented a two-session patient education protocol using the Cognitive Orientation to Occupational Performance (CO-OP) approach. Using the Patient-Specific Functional Scale (PSFS), participants identified and prioritized three therapy goals and rated their perceived current performance. Results demonstrated a significant difference between the participants’ PSFS pre and post-intervention scores. Patients’ improved self-perceived goal attainment scores served as evidence that, in addition to using …

What Does Walk Score® Really Measure?, Jorge Simbaqueba

Master's Theses

The Walk Score® (WS) algorithm works by identifying the closest amenities (grocery stores, banks, restaurants, and schools) and awarding points based on the distance to them from a given location. Scores have a range between 0 and 100. In 2011, the Walk Score® (WS) founders and advisory board modified the algorithm to better account for pedestrian friendliness by adding block length and intersection density data into the model to represent roadway characteristics and named it Street Smart Walk Score®.

Modelers attempting to quantify accessibility often focus on two components: a transportation element (or resistance factor) and an activity element (or …