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Articles 3631 - 3660 of 62007
Full-Text Articles in Entire DC Network
Efficacy Of Different Vaccination Programs Of Recombinant Hvt-Ndv Vaccine Against Genotype Vii Ndv Challenge In Broiler Chickens, Nataya Charoenvisal, Bubpa Supannamoke, Rik Koopman, Jiroj Sasipreeyajan
Efficacy Of Different Vaccination Programs Of Recombinant Hvt-Ndv Vaccine Against Genotype Vii Ndv Challenge In Broiler Chickens, Nataya Charoenvisal, Bubpa Supannamoke, Rik Koopman, Jiroj Sasipreeyajan
The Thai Journal of Veterinary Medicine
This study determined the efficacy of recombinant HVT- NDV ( rHVT- NDV) vaccine simultaneously vaccinated with live vaccine at 1 day old and a booster vaccination with live vaccine at 10 days old against Asiatic, Genotype VII NDV in broiler chickens. The chickens were divided into 5 groups. The chickens in groups 1, 2 and 3 were vaccinated with rHVT- NDV vaccine and different live vaccines at 1 day old, and then finally received a booster vaccination at 10 days old. The chickens in groups 4 and 5 served as the positive and negative control groups, respectively. The chickens in …
A Preliminary Study On Diversity Of Midgut Microbiota In Aedes Aegypti (Linnaeus) And Culex Quinquefasciatus (Say) Collected From Bangkok, Thailand, Sonthaya Tiawsirisup, Jirinnut Sirijutalak, Mananya Sondang, Manunya Supol, Nut Ansusinha, Ranida Tuanudom, Channarong Rodkhum
A Preliminary Study On Diversity Of Midgut Microbiota In Aedes Aegypti (Linnaeus) And Culex Quinquefasciatus (Say) Collected From Bangkok, Thailand, Sonthaya Tiawsirisup, Jirinnut Sirijutalak, Mananya Sondang, Manunya Supol, Nut Ansusinha, Ranida Tuanudom, Channarong Rodkhum
The Thai Journal of Veterinary Medicine
Aedes aegypti and Culex quinquefasciatus are important mosquito vectors for many infectious diseases. A number of factors affect the vector competence of these mosquitoes for a specific pathogen. The bacteria harbored in the midgut are known to influence mosquito physiology and can alter the response to various pathogens. Bacteria from the midgut of Ae. aegypti and Cx. quinquefasciatus were cultured and identified using bacteriological and molecular techniques in this study in which two groups of mosquitoes were examined. The first group was laboratory- reared, and the second group were field- collected mosquitoes from Bangkok. Twelve bacterial genera ( i. e. …
Oxidative Stress And Antioxidant In Canine Cutaneous Mast Cell Tumors, Arayaporn Macotpet, Ekkachai Pattarapanwichien, Fanan Suksawat, Patcharee Boonsiri
Oxidative Stress And Antioxidant In Canine Cutaneous Mast Cell Tumors, Arayaporn Macotpet, Ekkachai Pattarapanwichien, Fanan Suksawat, Patcharee Boonsiri
The Thai Journal of Veterinary Medicine
Oxidative stress can result from either the excessive production of reactive oxygen species (ROS) or an impaired antioxidant system, or both. It causes damage to lipids, proteins and DNA. Therefore, oxidative stress may be involved in carcinogenesis, and is associated with many types of cancer in dogs. The objective of this study was to compare the levels of malondialdehyde, protein hydroperoxides, glutathione, retinol and alpha-tocopherol between dogs with mast cell tumors and clinically healthy controls. Blood samples were obtained from eighteen clinically healthy dogs and fourteen dogs with spontaneous mast cell tumors. Malondialdehyde and protein hydroperoxides levels were measured by …
Impact Of Feed Characteristics For Monitoring Afb1 Contamination In Commercial Concentrate Feeds Used In Small Holder Dairy Farms, Chiangmai, Thailand, Wasana Chaisri, Wantanwa Mongkon, Yoshigo Sugita-Konishi, Witaya Suriyasathaporn
Impact Of Feed Characteristics For Monitoring Afb1 Contamination In Commercial Concentrate Feeds Used In Small Holder Dairy Farms, Chiangmai, Thailand, Wasana Chaisri, Wantanwa Mongkon, Yoshigo Sugita-Konishi, Witaya Suriyasathaporn
The Thai Journal of Veterinary Medicine
The objective of this study was to determine the impact of abnormal physical characteristics for monitoring aflatoxin B1 (AFB1) contamination in commercial dairy concentrate feeds. The study was conducted during March to May 2013 using 82 dairy farms in Chiang Mai province, Thailand. All feed samples were collected from new packages and their physical characteristics were subsequently determined. AFB1 concentrations in the samples were measured using the enzyme-linked immunosorbent assay (ELISA), and feed samples with AFB1 of more than 5 µg/Kg were determined as AFB1 contaminated samples. The impact of physical characteristics on AFB1 contamination were evaluated using a multiple …
Survival Time And Prognosis Factors In Hypertrophic Cardiomyopathy Cats With Congestive Heart Failure, Lalida Tantisuwat, Panduangjai Puangampai, Pornchanok Panpakdee, Thitinan Tangarsasilp, Sirilak Disatian Surachetpong
Survival Time And Prognosis Factors In Hypertrophic Cardiomyopathy Cats With Congestive Heart Failure, Lalida Tantisuwat, Panduangjai Puangampai, Pornchanok Panpakdee, Thitinan Tangarsasilp, Sirilak Disatian Surachetpong
The Thai Journal of Veterinary Medicine
Hypertrophic cardiomyopathy (HCM) is a common myocardial disease in cats. Nowadays, there is no study determining the survival time of cats affected with HCM in Thailand. This study aimed to evaluate the survival time in HCM cats with congestive heart failure (CHF) in Thailand and to determine the factors associating with survival time. A retrospective study was performed in 47 HCM cats to analyze survival time and the association of survival time and factors including sex, age, breeds, weight, physical findings, the presence of complications, medication and echocardiographic findings. The data was analyzed by the Log-Rank test and displayed with …
Emergence Of A Classical Variant Of Porcine Epidemic Diarrhea Virus Novel To Thailand Responsible For The Milder Clinical Disease In A Herd Previously Infected With A Pandemic Variant, Gun Temeeyasen, Anchalee Srijangwad, Thitima Tripipat, Angkana Tantituvanont, Dachrit Nilubol
Emergence Of A Classical Variant Of Porcine Epidemic Diarrhea Virus Novel To Thailand Responsible For The Milder Clinical Disease In A Herd Previously Infected With A Pandemic Variant, Gun Temeeyasen, Anchalee Srijangwad, Thitima Tripipat, Angkana Tantituvanont, Dachrit Nilubol
The Thai Journal of Veterinary Medicine
In 2014, porcine epidemic diarrhea (PED) outbreaks characterized by mild clinical disease and low preweaning mortality increased in frequency in Thailand. An outbreak investigation, based on the detection of the classical variant and the allowance of the herd owners, was conducted in 5 swine herds and 25 intestinal samples were submitted from herds with outbreaks of diarrhea for sequencing analysis. PEDV isolation and complete nucleotide sequences of the spike (S) glycoprotein were determined. The PEDV isolate EAS1 was identified. Phylogenetic analysis based on the full-length spike gene demonstrated that EAS1 belonged to the classical variant group with high nucleotide and …
Effectiveness Of Sentinel Rodents For Surveillance Of Exposure To Undocumented Bacterial Pathogens In Animal Research Facility, Shih-Keng Loong, Haryanti-Azura Mohammad-Wali, Nurul-Asma-Anati Che-Mat-Seri, Nur-Hidayana Mahfodz, Dzuzaini Mohd-Ghazali, Pooi-Fong Wong, Sazaly Abubakar
Effectiveness Of Sentinel Rodents For Surveillance Of Exposure To Undocumented Bacterial Pathogens In Animal Research Facility, Shih-Keng Loong, Haryanti-Azura Mohammad-Wali, Nurul-Asma-Anati Che-Mat-Seri, Nur-Hidayana Mahfodz, Dzuzaini Mohd-Ghazali, Pooi-Fong Wong, Sazaly Abubakar
The Thai Journal of Veterinary Medicine
The use of sentinel animals in animal research facilities is the cornerstone of animal health monitoring for exposure to natural pathogens of laboratory animals. This is because infection with these pathogens produces no overt signs of disease yet the infection may affect the outcome of research utilising these animals. One of the important pathogens includes Klebsiella pneumoniae, whose prevalence can be high in laboratory animals. This study sought to document the prevalence of K. pneumoniae and other undocumented bacterial pathogens in laboratory rodents for a 3- year period. K. pneumoniae and Chryseobacterium gleum were isolated from sentinel ICR mice housed …
Effects Of Supplementing Varying Levels Of 1,3-Diacylglycerol (Dag) On Growth Performance, Apparent Nutrient Digestibility And Selected Fecal Microbial Populations In Growing Pigs, Wen Chao Liu, Kwan Sik Yun, In Ho Kim
Effects Of Supplementing Varying Levels Of 1,3-Diacylglycerol (Dag) On Growth Performance, Apparent Nutrient Digestibility And Selected Fecal Microbial Populations In Growing Pigs, Wen Chao Liu, Kwan Sik Yun, In Ho Kim
The Thai Journal of Veterinary Medicine
The objective of the present study was to investigate the effects of 1,3-diacylglycerol (DAG) supplementation on growth performance, apparent digestibility and selected fecal microbial populations in growing pigs. A total of 80 crossbred pigs [(Landrace × Yorkshire) × Duroc] with an average initial body weight (BW) of 27.52 ± 0.20 kg were used in a 6 week feeding trial. Pigs were allotted to 4 dietary treatments based on their initial BW and sex (5 replications; 4 pigs per pen with 2 barrows and 2 gilts). Dietary treatments included: 1) CON, basal diets; 2) CON+0.075% 1,3-DAG; 3) CON+0.10% 1,3-DAG; 4) CON+0.15% …
Comparative Ultrasonographic And Computed Tomographic Images Of The Adrenal Glands Of Healthy Cats, Panrawee Phoomvuthisarn, Kiatpichet Komin, Nan Choisunirachon
Comparative Ultrasonographic And Computed Tomographic Images Of The Adrenal Glands Of Healthy Cats, Panrawee Phoomvuthisarn, Kiatpichet Komin, Nan Choisunirachon
The Thai Journal of Veterinary Medicine
Feline adrenal disorders that affect the size of the adrenal glands can be detected by diagnostic imaging including ultrasonography and Computed Tomography (CT). The objectives of this study were to compare the appearance of the adrenal gland in healthy cats between these two techniques and establish the reference values of the CT dimensions of the adrenal gland in cats. We found that there was no significant difference in the length of both adrenal glands between the two techniques but the cranial and caudal heights of the left adrenal glands and cranial height of the right adrenal gland obtained from the …
What Is Your Diagnosis?, Ninlawan Thammasiri, Nan Choisunirachon
What Is Your Diagnosis?, Ninlawan Thammasiri, Nan Choisunirachon
The Thai Journal of Veterinary Medicine
A thirteen kilograms, 6-year-old, male, Shih Tzu dog.
Rapid Separation Of Bacteria From Blood For Sepsis Diagnosis, Mahsa Alizadeh
Rapid Separation Of Bacteria From Blood For Sepsis Diagnosis, Mahsa Alizadeh
Theses and Dissertations
Sepsis is a severe blood infection caused by bacteria entering the blood stream. Sepsis caused by antibiotic resistant bacteria is very dangerous with a high mortality rate. The current clinical diagnostic methods for sepsis require culturing the blood sample prior to other steps of the diagnosis procedure. Culturing the blood samples is a time-consuming step which increases the time required for the diagnostic procedure. Considering the fact that the mortality rate of the sepsis increases as time passes, it is essential to find methods for sepsis diagnosis that do not require culturing the samples. The first step of a new …
Microenvironmental Forces Regulate Notch Signaling Through Integrins, Michael Allen Detweiler
Microenvironmental Forces Regulate Notch Signaling Through Integrins, Michael Allen Detweiler
Boise State University Theses and Dissertations
The extracellular microenvironment contributes significantly to a cell’s function and behavior. For instance, cell-cell interactions, cell-substrate interactions, and physical forces are all factors of the extracellular environment that can alter cellular behavior. Cells can receive these signals and forces through various membrane channels and receptors that transmit the signals from the extracellular to the intracellular space. Canonical Notch signaling is induced by ligand interactions with neighboring cells, but recent evidence has revealed that Notch signaling can occur through a variety of extracellular stimuli including hyperglycemia, hypoxia, multiple growth factors, fluid shear stress, and extracellular matrix (ECM) composition. Although Notch activation …
Privacy-Preserving Genomic Data Publishing Via Differential Privacy, Tanya Khatri
Privacy-Preserving Genomic Data Publishing Via Differential Privacy, Tanya Khatri
Boise State University Theses and Dissertations
Privacy-preserving data publishing is a mechanism for sharing data while ensuring the privacy of individuals is preserved in the published data and utility is maintained for data mining and analysis. There is a huge need for sharing genomic data to advance medical and health research. However, since genomic data is highly sensitive and the ultimate identifier, it is a big challenge to publish genomic data while protecting the privacy of individuals in the data.
In this thesis, we address the aforementioned challenge by presenting an approach for privacy-preserving genomic data publishing via differentially-private suffix tree. The proposed algorithm uses a …
Statistical Analysis And Estimation Of The Regional Trend Of Aerosol Size Over The Arabian Gulf Region During 2002-2016, Alina Barbulescu, Yousef Nazzal, Fares Howari
Statistical Analysis And Estimation Of The Regional Trend Of Aerosol Size Over The Arabian Gulf Region During 2002-2016, Alina Barbulescu, Yousef Nazzal, Fares Howari
All Works
© 2018 The Author(s). In this article, we present the results of the regional estimation of the evolution of monthly mean aerosol size over the Arabian Gulf Region, based on the data collected during the period July 2002 - September 2016. The dataset used is complete, without missing values. Two methods are introduced for this purpose. The first one is based on the partition of the regional series in sub-series and the selection of the most representative one for fitting the regional trend. The second one is a version of the first method, combined with the k-means clustering algorithm. Comparison …
Chitosan/Ag-Hydroxyapatite Nanocomposite Beads As A Potential Adsorbent For The Efficient Removal Of Toxic Aquatic Pollutants, Long Li, Jibran Iqbal, Ying Zhu, Peng Zhang, Wanchao Chen, Amit Bhatnagar, Yiping Du
Chitosan/Ag-Hydroxyapatite Nanocomposite Beads As A Potential Adsorbent For The Efficient Removal Of Toxic Aquatic Pollutants, Long Li, Jibran Iqbal, Ying Zhu, Peng Zhang, Wanchao Chen, Amit Bhatnagar, Yiping Du
All Works
© 2018 Elsevier B.V. In the present study, the potential of synthesized chitosan/Ag-substituted hydroxyapatite nanocomposite beads to remove basic dye, heavy metal and microbes from aqueous solutions was investigated. Beads were prepared in different ratios via embedding of Ag-hydroxyapatite (Ag-HA) into chitosan (CS) solution. The beads were characterized by Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM) in order to get an insight of the functional groups and morphology. Batch adsorption studies were conducted with copper ions (Cu (II)) and rhodamine B (RhB) dye by changing several parameters such as Ag-HA to Cs ratio, contact time, solution pH …
Desert Plant Bacteria Reveal Host Influence And Beneficial Plant Growth Properties, Abdul Aziz Eida, Maren Ziegler, Feras F. Lafi, Craig T. Michell, Christian R. Voolstra, Heribert Hirt, Maged M. Saad
Desert Plant Bacteria Reveal Host Influence And Beneficial Plant Growth Properties, Abdul Aziz Eida, Maren Ziegler, Feras F. Lafi, Craig T. Michell, Christian R. Voolstra, Heribert Hirt, Maged M. Saad
All Works
© 2018 Eida et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Deserts, such as those found in Saudi Arabia, are one of the most hostile places for plant growth. However, desert plants are able to impact their surrounding microbial community and select beneficial microbes that promote their growth under these extreme conditions. In this study, we examined the soil, rhizosphere and endosphere bacterial communities of four native desert plants Tribulus terrestris, Zygophyllum simplex, …
Types Of Tobacco Consumption And The Oral Microbiome In The United Arab Emirates Healthy Future (Uaehfs) Pilot Study, Yvonne Vallès, Claire K. Inman, Brandilyn A. Peters, Raghib Ali, Laila Abdel Wareth, Abdishakur Abdulle, Habiba Alsafar, Fatme Al Anouti, Ayesha Al Dhaheri, Divya Galani, Muna Haji, Aisha Al Hamiz, Ayesha Al Hosani, Mohammed Al Houqani, Abdulla Al Junaibi, Marina Kazim, Tomas Kirchhoff, Wael Al Mahmeed, Fatma Al Maskari, Abdullah Alnaeemi, Naima Oumeziane, Ravichandran Ramasamy, Ann Marie Schmidt, Michael Weitzman, Eiman Al Zaabi, Scott Sherman, Richard B. Hayes, Jiyoung Ahn
Types Of Tobacco Consumption And The Oral Microbiome In The United Arab Emirates Healthy Future (Uaehfs) Pilot Study, Yvonne Vallès, Claire K. Inman, Brandilyn A. Peters, Raghib Ali, Laila Abdel Wareth, Abdishakur Abdulle, Habiba Alsafar, Fatme Al Anouti, Ayesha Al Dhaheri, Divya Galani, Muna Haji, Aisha Al Hamiz, Ayesha Al Hosani, Mohammed Al Houqani, Abdulla Al Junaibi, Marina Kazim, Tomas Kirchhoff, Wael Al Mahmeed, Fatma Al Maskari, Abdullah Alnaeemi, Naima Oumeziane, Ravichandran Ramasamy, Ann Marie Schmidt, Michael Weitzman, Eiman Al Zaabi, Scott Sherman, Richard B. Hayes, Jiyoung Ahn
All Works
© 2018, The Author(s). Cigarette smoking alters the oral microbiome; however, the effect of alternative tobacco products remains unclear. Middle Eastern tobacco products like dokha and shisha, are becoming globally widespread. We tested for the first time in a Middle Eastern population the hypothesis that different tobacco products impact the oral microbiome. The oral microbiome of 330 subjects from the United Arab Emirates Healthy Future Study was assessed by amplifying the bacterial 16S rRNA gene from mouthwash samples. Tobacco consumption was assessed using a structured questionnaire and further validated by urine cotinine levels. Oral microbiome overall structure and specific taxon …
Epilepsy, Identity, And The Experience Of The Body, Stephanie Kılınç, Carol Campbell, Alison Guy, Anna Van Wersch
Epilepsy, Identity, And The Experience Of The Body, Stephanie Kılınç, Carol Campbell, Alison Guy, Anna Van Wersch
All Works
© 2018 Elsevier Inc. Living with a chronic condition can challenge a person's identity, yet there is a paucity of research exploring this experience for people with epilepsy and particularly for those diagnosed in adulthood. Consequently, through an interpretative phenomenological approach, the current study aimed to explore what the experience of adult-onset epilepsy meant for a person's identity. Thirty-nine people with adult-onset epilepsy from across the UK took part in up to two semi-structured interviews. A modified form of interpretative phenomenological analysis was conducted and identified three themes: 1) disarming the impact of seizures considered strategies used to control seizure …
Hapke-Based Computational Method To Enable Unmixing Of Hyperspectral Data Of Common Salts, Fares M. Howari, Gheorge Acbas, Yousef Nazzal, Fatima Alaydaroos
Hapke-Based Computational Method To Enable Unmixing Of Hyperspectral Data Of Common Salts, Fares M. Howari, Gheorge Acbas, Yousef Nazzal, Fatima Alaydaroos
All Works
© 2018, The Author(s). Environmental scientists are currently assessing the ability of hyper-spectral remote sensing to detect, identify, and analyze natural components, including minerals, rocks, vegetation and soil. This paper discusses the use of a nonlinear reflectance model to distinguish multicomponent particulate mixtures. Analysis of the data presented in this paper shows that, although the identity of the components can often be found from diagnostic wavelengths of absorption bands, the quantitative abundance determination requires knowledge of the complex refractive indices and average particle scattering albedo, phase function and size. The present study developed a method for spectrally unmixing halite and …
Climate Change Perceptions And Adaptation Among Small-Scale Farmers In Uganda: A Community-Based Participatory Approach, Thomas Derr
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Climate change in the East African country of Uganda is causing severe variations in the once predictable seasonal weather patterns that farmers had come to depend on. This, in combination with social and economic challenges, has significantly increased the vulnerability of farmers who make up the majority of Uganda’s population. Previous knowledge and observations suggest that Ugandan farmers may be reluctant or slow to change their practices in response to the changing climate. Strategies are therefore needed to identify challenges and sustainable solutions. This research used qualitative data collection methods known as participatory rural appraisal (PRA) and participatory action research …
Tanf Funding Allocation Differences In Red Vs. Blue States: Emphasis On Out-Of-Wedlock Births And Divorces, Camille Mindrum
Tanf Funding Allocation Differences In Red Vs. Blue States: Emphasis On Out-Of-Wedlock Births And Divorces, Camille Mindrum
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The 1996 welfare reforms were part of a bipartisan consensus led by Democratic President Bill Clinton and a Republican Congress about the downfalls of the existing United States welfare system. Under these reforms, Temporary Assistance for Needy Families (TANF) replaced Aid to Families with Dependent Children (AFDC), which was an entitlement program that had been in effect since 1935. Similar to AFDC, TANF intended to serve as a safety net that provides cash assistance to needy families, but it also aimed to reduce government dependence by attempting to instill values in welfare recipients through stricter work requirements and eligibility criteria. …
Training Non-Board Certified Behavior Analyst (Bcba) Behavior Specialists To Conduct Trial-Based Functional Analyses In Residential Settings, Devon S. Millington
Training Non-Board Certified Behavior Analyst (Bcba) Behavior Specialists To Conduct Trial-Based Functional Analyses In Residential Settings, Devon S. Millington
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
This study investigated a process for identifying the reasons why a person with an intellectual disability has problem behaviors. This process is called a trial-based functional analysis (TBFA). The researchers wanted to know if a person who was not an expert behavior analyst could be trained to perform the TBFA and if the results obtained from the TBFA could be used to create a program to reduce the problem behavior of a person with an intellectual disability living in a community-based group home for persons with disabilities. The results of this study show that a person who is not an …
Successful Anesthetic Management Of Patient With Stiff Person Syndrome, Muhammad Sohaib, Sarfraz Siddiqui
Successful Anesthetic Management Of Patient With Stiff Person Syndrome, Muhammad Sohaib, Sarfraz Siddiqui
Department of Anaesthesia
We herein describe the successful anesthetic management of a patient with stiff person syndrome undergoing right total hip replacement under spinal anesthesia. We also describe the problems associated with general anesthesia. The advantage of using regional anesthesia in these patients is the avoidance of muscle relaxants. The use of general anesthesia carries the risk of hypotonia in stiff person syndrome postoperatively due to enhancement of γ aminobutyric acid (GABA) action on synaptic transmission by drugs that have a γ GABA agonistic action.
Financial Planning Mechanisms Available To Persons With Special Needs In Singapore, Hang Wu Tang
Financial Planning Mechanisms Available To Persons With Special Needs In Singapore, Hang Wu Tang
Research Collection Yong Pung How School Of Law
A woefully underinvestigated area of the law is the management of property rights of persons with special needs. In this chapter, the term ‘special needs’ is defined widely to include people who are incapable of managing their daily financial affairs. The scope of people within this group may include persons with dementia, schizophrenia and intellectual disability as well as vulnerable elders. It should be noted that persons with special needs may have accumulated substantial property before becoming incapable of managing their financial affairs by reason of illness, old age or dementia. Alternatively, they could have inherited or stand to inherit …
The Development Of A Reliable Change Index And Cutoff For The Score-15, Cara Ann Nebeker Adams
The Development Of A Reliable Change Index And Cutoff For The Score-15, Cara Ann Nebeker Adams
Theses and Dissertations
The Systemic Clinical Outcome and Routine Evaluation version 15 (SCORE-15) is an assessment used to assess for clinical change in family functioning. The SCORE-15 has been demonstrated in the past to be a reliable and valid measure for assessing for clinical change and is largely used throughout the UK. However, the SCORE-15 lacks the ability to determine whether an individual's change in family functioning is clinically significant. This study aims to establish a reliable change index and clinical cutoff score based on a US sample so that researchers and clinicians can determine clinically significant change. A sample of 63 clinical …
Innate Immune Cell Phenotypes Are Dictated By Distinct Epigenetic Reprogramming, Kevin Douglas Adams
Innate Immune Cell Phenotypes Are Dictated By Distinct Epigenetic Reprogramming, Kevin Douglas Adams
Theses and Dissertations
The innate immune system is the first line of host defense against external exposures. During these initial encounters, antigen presenting cells - specifically monocytes and macrophages - modulate further inflammatory responses. Macrophages exist along a spectrum of phenotypic programs; on the inflammatory M1 end they enhance immune activity while on the anti-inflammatory M2 end they suppress further immune activation. Furthermore, within M2 macrophages there exist many subpopulations, namely M2a and M2d, each with specific roles during infection or exposure. We sought to compare the epigenetic profiles of these subpopulations of macrophages to determine key regulatory gene networks and factors that …
Bobcat Abundance And Habitat Selection On The Utah Test And Training Range, Kyle David Muncey
Bobcat Abundance And Habitat Selection On The Utah Test And Training Range, Kyle David Muncey
Theses and Dissertations
Remote cameras have become a popular tool for monitoring wildlife. We used remote cameras to estimate bobcat (Lynx rufus) population abundance on the Utah Test and Training Range during two sample periods between 2015 and 2017. We used two statistical methods, closed capture mark-recapture (CMR) and mark-resight Poisson log-normal (PNE), to estimate bobcat abundance within the study area. We used the maximum mean distance moved method (MMDM) to calculate the effective sample area for estimating density. Additionally, we captured bobcats and estimated home range using minimum convex polygon (MCP) and kernel density estimation (KDE) methods. Bobcat abundance on the UTTR …
Loss-Of-Function Mutations In Atp6ap1 And Atp6ap2 In Granular Cell Tumors., Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino De Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. Da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I.A. Edelweiss, Juan P. Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, Jorge S. Reis-Filho
Loss-Of-Function Mutations In Atp6ap1 And Atp6ap2 In Granular Cell Tumors., Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino De Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. Da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I.A. Edelweiss, Juan P. Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, Jorge S. Reis-Filho
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
Granular cell tumors (GCTs) are rare tumors that can arise in multiple anatomical locations, and are characterized by abundant intracytoplasmic granules. The genetic drivers of GCTs are currently unknown. Here, we apply whole-exome sequencing and targeted sequencing analysis to reveal mutually exclusive, clonal, inactivating somatic mutations in the endosomal pH regulators ATP6AP1 or ATP6AP2 in 72% of GCTs. Silencing of these genes in vitro results in impaired vesicle acidification, redistribution of endosomal compartments, and accumulation of intracytoplasmic granules, recapitulating the cardinal phenotypic characteristics of GCTs and providing a novel genotypic-phenotypic correlation. In addition, depletion of ATP6AP1 or ATP6AP2 results in …
Summer Camp Youth Leadership Development: An Investigation Of Adolescents’ Perceptions Of Best Practices, Katlyn Martin
Summer Camp Youth Leadership Development: An Investigation Of Adolescents’ Perceptions Of Best Practices, Katlyn Martin
Journal of Youth Development
This qualitative study explored adolescent participants’ perceptions of the Leaders-in-Training (LIT) program at Waycross Camp, a residential summer camp. The main data set was collected through interviews with former LIT program participants. A constant comparison data analysis of LIT program feedback revealed four emergent themes: (a) bridging the gap, (b) giving permission to be human, (c) rolling up your sleeves, and (d) serving the greater good. Each theme yielded an outcome, including (a) community, (b) openness, (c) empowerment, and (d) character, respectively. Concepts depicted in relevant literature were synthesized with these four themes and outcomes, yielding (a) social relationships; (b) …
Young Adult Counselors With Diabetes At Diabetes Camps: The Effect Of Being A Peer Mentor On Counselors’ Health Behavior, Alison Stein Manning, Mclean Pollock, Ben Clements, Elissa Furutani
Young Adult Counselors With Diabetes At Diabetes Camps: The Effect Of Being A Peer Mentor On Counselors’ Health Behavior, Alison Stein Manning, Mclean Pollock, Ben Clements, Elissa Furutani
Journal of Youth Development
Adolescents and young adults (AYA) with type I diabetes (T1D) often struggle with illness management. Although diabetes camps have been shown to improve blood sugar control among campers, the effect of the camp experience on counselors’ diabetes self-management has never been studied. In addition to the camp environment, it was hypothesized that peer factors among counselors, such as diabetes role modeling, would positively influence diabetes self-care behaviors and that counselors would be able to select diabetes role models based on these appropriate self-management behaviors. Counselors with T1D working at 2 summer camps were recruited to participate. Participants completed questionnaires including …