Digital Commons Network^™

Type I Interferon Potentiates Iga Immunity To Respiratory Syncytial Virus Infection During Infancy, Diego R. Hijano, David T. Siefker, Bishwas Shrestha, Sridhar Jaligama, Luan D. Vu, Heather Tillman, David Finkelstein, Jordy Saravia, Dahui You, Stephania A. Cormier

Faculty Publications

© 2018, The Author(s). Respiratory syncytial virus (RSV) infection is the most frequent cause of hospitalization in infants and young children worldwide. Although mucosal RSV vaccines can reduce RSV disease burden, little is known about mucosal immune response capabilities in children. Neonatal or adult mice were infected with RSV; a subset of neonatal mice received interferon alpha (IFN-α) (intranasal) prior to RSV infection. B cells, B cell activating factor (BAFF) and IgA were measured by flow cytometry. RSV specific IgA was measured in nasal washes. Nasal associated lymphoid tissue (NALT) and lungs were stained for BAFF and IgA. Herein, we …

Towards A Better Understanding Of The Effects Of Praziquantel On The Interaction Between The Helminth Parasite Schistosoma Mansoni And Its Murine Host, Melissa Catherine Sanchez

Biology ETDs

Schistosomiasis is a neglected tropical disease (NTD) that infects 206 million individuals worldwide. This disease is caused by dioecious trematodes of the genus Schistosoma, and its pathology is associated with the large number of eggs that are released by the female. Entrapped eggs lead to host immune and inflammatory responses resulting in disease progression. Chemotherapy provides the main means of control and praziquantel (PZQ) is the only widely available drug that is used in all mass drug administration (MDA) programs. As the number of individuals receiving PZQ continues to grow, the development of PZQ resistance is a concern and …

Structure-Activity Relationship Of Novel Rgd-Containing Cyclic Peptides Against Αvβ3 Integrin, Aaron Silva

Honors Theses

The αvβ3 integrin, a receptor for many extracellular matrix proteins with the RGD sequence motif, is involved in multiple physiological processes. The integrin is highly expressed on tumor cells, therefore making it a target for cancer therapy and imaging. Efforts have been made to develop an RGD-containing ligand against the αvβ3 integrin.

A series of RGD-containing cyclic octapeptides (LXW analogs) were previously synthesized, tested in vitro, and screened as integrin antagonists with a different binding affinity (Xiao et al., 2010; Wang et al., 2015), but the structure-activity relationship remains to be elucidated. In the current study, the structures of three …

Vertical Transmission Of Zika Virus In Aedes Aegypti And Aedes Albopictus, Stephanie Cantu

Honors Theses

Arboviruses such as Zika (ZIKV), dengue, chikungunya are responsible causing over 4 million people to live with debilitating conditions and may produce long-term health consequences. Zika virus, a newly emerging arbovirus, has potentially severe neurological complications and a potential to cause severe birth defects. There are no current vaccines for Zika virus, and the primary method for control the spread of this disease is through early detection and vector control. Assessing and quantifying viral transmission patterns is critical for successful control efforts. Zika virus shows some unique (among arboviruses) transmission patterns, notably the ability to be sexually transmitted. One aspect …

Research & Development Of A Sensory Exploration System, Surabhi Vijay Rajandekar

Theses

Learning Disabilities affect individuals in all age groups and affect how one comprehends the information they receive. Individuals with learning disabilities are often distracted by their surroundings and face difficulties to follow paths in surroundings. Learning disabilities can be addressed with proper support, feedback, and assistive technology. Schools provide children a favorable environment to learn and can support overcoming such difficulties with the help of different activities. This paper discusses the design of a sensory exploration system for individuals with Autism Spectrum to help them learn how to follow paths and not get distracted. The sensory exploration system is called …

The Dark Side Of Tribal Sovereign Immunity: The Gap Between Law And Remedy, Alma Orozco

Nevada Law Journal

No abstract provided.

University Title Ix Compliance: A Work In Progress In The Wake Of Reform, Michelle J. Harnik

Nevada Law Journal

No abstract provided.

The Thirteenth Amendment And Minimum Wage Laws, Ruben J. Garcia

Nevada Law Journal

No abstract provided.

Table Of Contents, Editorial Board, Law School Faculty And Administration, University Of Nevada, Las Vegas -- William S. Boyd School Of Law

Nevada Law Journal

No abstract provided.

Root And Branch: The Thirteenth Amendment And Environmental Justice, Mehmet K. Konar-Steenberg

Nevada Law Journal

No abstract provided.

Popularity, Safety And Quality Of Homoeopathic Medicines, Raj Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

World Integrated Medicine Forum 2017: A Feedback Survey Analysis, Anupriya Chaudhary, Harleen Kaur, Jyoti Sachdeva, Mohua Dutta, Anil Khurana, Robbert Van Haselen, Raj Manchanda

Indian Journal of Research in Homoeopathy

Introduction: The first-of-its-kind World Integrated Medicine Forum (WIMF) on the regulation of homoeopathic medicinal products (HMPs) which was attended by various stakeholders from 23 countries witnessed rigorous discussions to strengthen existing regulatory framework of homoeopathic medicines in the world, as well as to bring harmony within the Homoeopathy market for drug manufacture standards including pharmacopoeial convergence. Materials and Methods: A feedback questionnaire was shared with the participants through SurveyMonkey online platform to seek their opinion about the Forum, obtain their country-specific views about regulations of HMPs, to evaluate the extent to which the Forum could meet its objectives and also …

Effect Of Individualised Homoeopathy In The Treatment Of Infertility, Suraia Parveen, Himadri Bhaumik

Indian Journal of Research in Homoeopathy

A 37-year-old woman, being married for 6 years, presented to the homoeopathic outpatient department, after treatment of infertility by a gynaecologist for few years. She had a past history of emergency ovarian cystectomy for endometriosis 1 year after her marriage. Her subsequent infertility workup revealed hydrosalpinx with one-sided tubal block along with the evidence of poor ovarian reserve. Her husband's semen analysis was normal and was advised for donor-ovum in vitro fertilisation. At this point, she was treated with constitutional homoeopathic medicine following the miasmatic analysis with the holistic concept of Homoeopathy over 6 months. Treatment started with Silicea and …

A Low-Intensity, Hybrid Design Between A "Traditional" And A "Course-Based" Research Experience Yields Positive Outcomes For Science Undergraduate Freshmen And Shows Potential For Large-Scale Application, Thushani Rodrigo-Peiris, Lin Xiang, Vincent M. Cassone

Biology Faculty Publications

Based on positive student outcomes, providing research experiences from early undergraduate years is recommended for science, technology, engineering, and mathematics (STEM) majors. To this end, we designed a novel research experience called the “STEMCats Research Experience” (SRE) for a cohort of 119 second-semester freshmen with diverse college preparatory levels, demographics, and academic majors. The SRE targeted student outcomes of enhancing retention in STEM majors, STEM competency development, and STEM academic performance. It was designed as a hybrid of features from apprenticeship-based traditional undergraduate research experience and course-based undergraduate research experience designs, considering five factors: 1) an authentic research experience, 2) …

Sustainable Manufacturing Of Natural Fiber Reinforced Green Composite, Kousaalya Bakthavatchalam

All Dissertations

Amidst growing concerns about environmental sustainability, the renewed push towards adoption of circular economy has increased focus among several manufacturing sectors on using renewable resources and improving process efficiencies. From the materials standpoint, use of bio-based polymers and natural fibers as sustainable reinforcements are increasingly gaining market share. However, conventional processing methods for fiber reinforced composites are usually energy-intensive and often involve long processing times, which may lead to detrimental environmental impacts. In this context, a holistic attainment of sustainability makes it imperative to adapt sustainable practices not only for raw materials but at every stage of the product. Hence, …

High-Achieving, Non-First-Generation, Female, Undergraduate Student Views Of Family Influence On Career Decisions, Katryna Bower Maxwell

All Dissertations

This qualitative study sought to understand how high-achieving, non-first-generation, female, undergraduate students viewed the influence parents and families had on their career decisions. This study’s six participants were students in the same honors college at a large, four-year, public university in the Southeast United States. Data from a pre-interview survey, initial interview, in-depth interview, and interview observation protocols were used to understand participants’ career decision-making processes and the influence their parents and families had on those processes. Thematic coding was used to identify three common themes found among participants: (a) parent and family support (b) family influence on career decision-making …

On Some Environmental Applications Of Stochastic Processes, Liu Zhu

All Dissertations

This dissertation focuses on the study of some environmental applications of stochastic processes. In the first Chapter, we study an extreme value time series, where the extremes are derived using the block maxima/minima method. In extreme value analyses, the block maxima/minima are typically assumed to be statistically independent from block to block. However, extreme data arising from applications often present significant correlations. The main result of the chapter is to develop a simple and efficient method to estimate extreme model parameters and compute standard errors for them that account for correlation. More precisely, we develop a likelihood for sequences of …

State's Fiscal Dependency And Implications On Monetary Management In Nigeria, Akinboyo O. Lawrence, Apinran O. Martins

Bullion

This study examines fiscal management by States in Nigeria and its potential to sustain growth and development. The study used secondary data from the Bank's Statistical Bulletin and the Nigeria Bureau of Statistics. Information on monthly allocations to States, internally Generated Revenue, Debt stock, total Revenue, and Total expenditure were used to examine fiscal imbalance in the States. Data were collected on statutory allocations to States by the Federation Account Allocation Committee (FAAC), Internally Generated Revenue (IGR), States' debt stock, capital and recurrent expenditure from the Central Bank of Nigeria (CBN) and the National Bureau of Statistics (NBS). Descriptive statistics …

Editorial: Shared Learning Between Spoken And Signed Language Interpreters And Students, George Major, Ineke Crezee

International Journal of Interpreter Education

No abstract provided.

Designated Or Preferred? A Deaf Academic And Two Signed Language Interpreters Working Together For A Phd Defence: A Case Study Of Best Practice, Maartje De Meulder, Jemina M. Napier, Christopher Stone

International Journal of Interpreter Education

In this paper we present an appreciative inquiry case study of our work together in a PhD defence, which we believe demonstrates a best practice in the field of signed language interpreting. We call into question the meaning and relevance of the ‘designated interpreter’ model, examining whether there is a ‘perfect formula’ for deaf academics and interpreters working together, not only in PhD defences, but also in academia more generally. We also challenge the very system for the provision of interpreter services as an institution creating structural inequalities, because it is heavily based on privilege. We argue that what is …

Encountering Change: Job Satisfaction Of Sign Language Interpreters In Finland, Liisa Martikainen, Petri Karkkola, Matti Kuittinen

International Journal of Interpreter Education

The organizational system for providing Finnish sign language interpreter services has recently changed, and this change has influenced the whole interpretation service industry. It poses major challenges for the maintenance of job satisfaction among sign language professionals. The level of job satisfaction of sign language interpreters (in this study, N = 135) was surveyed by means of an online questionnaire. While examining this phenomenon, this study mainly addresses the systemic factors in employment conditions. According to the results, the level of job satisfaction among interpreters is quite high; however, it remains clearly lower than the average for Finnish workers. The …

Interview With Niki Baras, Translators And Interpreters Australia -A Division Of Professionals Australia, Oktay Eser, Miranda Lai

International Journal of Interpreter Education

Niki Baras represents the Translator and Interpreter Division of Professionals Australia, an amalgamated organization representing professionals from various fields with a mission to ensure their work is recognised and rewarded appropriately. This interview looks at the social status, respect and sustainability issues of community interpreters in Australia from an industrial point of view. After a brief overview of how the Translator and Interpreter Division came about under the organization, Niki explains the historical contexts in which the National Accreditation Authority for Translators and Interpreters in Australia was founded in 1977. After more than 40 years of development, community interpreting in …

Collusion, Obstruction Of Justice, And Impeachment, Ediberto Roman, Melissa Gonzalez, Dianet Torres

Journal of Legislation

No abstract provided.

There’S A Pill For That! State Law Approaches To Workplace Drug Testing Policy In The Age Of Prescription Opioids, Katie Meikle

Journal of Legislation

No abstract provided.

The Unconstitutionality Of The Protecting Access To Care Act Of 2017’S Cap On Noneconomic Damages In Medical Malpractice Cases, Kaeleigh P. Christie

Journal of Legislation

No abstract provided.

Lakeshore Modification Reduces Secondary Production Of Macroinvertebrates In Littoral But Not Deeper Zones, Marlene Pätzig, Yvonne Vadeboncoeur, Mario Brauns

Biological Sciences Faculty Publications

Littoral macroinvertebrates are an integral component of lake food webs, but their productivity may be affected by shoreline alteration. We hypothesized that human modification of lake shores simplifies habitat diversity, which, in turn, affects littoral macroinvertebrate production and patterns of depth–production relationships. Furthermore, we expected that lakeshore modification would favor nonnative species, potentially compensating for negative effects of lakeshore modification on production of native taxa. To test these ideas, we estimated benthic macroinvertebrate production in the upper littoral, middle littoral, and profundal zones of a large lowland lake (Lake Scharmützelsee) in Northeast Germany. We collected samples between April and November …

Effects Of An Educational Intervention On Exclusive Breastfeeding Rates In Marshallese Mothers Residing In The U.S., Connor K. Otto

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: The largest population of Marshallese immigrants in the Contiguous U.S. resides in Northwest Arkansas. Despite adequate access to healthcare, the Marshallese face many health disparities, perhaps partly due to the language barrier they face in healthcare settings and education. Regarding breastfeeding rates, women in the Marshall Islands have a significantly higher rate of exclusive breastfeeding than in Marshallese women residing in the U.S. who face cultural barriers. Breastfeeding is positively correlated to many benefits for infants and is recommended exclusively for at least 6 months by pediatric policy organizations.

Objective: The purpose of this research is to examine breastfeeding …

Changes In Cultural Competency Of Nurses Caring For Marshallese Islanders Following An Educational Intervention, Abigail Childers

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Abstract

Background: Marshall Islanders are one of the fastest growing migrant populations in the US and Northwest Arkansas. Health disparities and maintenance of strong cultural values and norms may adversely affect the Marshallese participation in the health care system. Evidence shows that cultural competency training can improve the attitudes, knowledge, skills and behaviors of health professionals and has many positive impacts. The Clinical Cultural Competency Questionnaire (CCCQ) is a research-validated tool that can be used to measure perceived cultural competency through many subscale categories.

Objective: The purpose of this study is to implement a cultural awareness educational program and to …

Social And Economic Adversity Experienced By Canadians And Everyday Legal Problems, Ab Currie, Lisa Moore

Canadian Forum on Civil Justice

As part of a national study on the Cost of Justice by the Canadian Forum on Civil Justice (CFCJ), over 3,000 adults in Canada were asked about their experiences with civil and family justice problems and their views on the justice system in Canada. Additionally, survey participants were asked generally if over several years they had experienced ongoing issues with debt, finding or securing good and affordable housing or with unemployment. These specific areas were canvassed as possible indicators of larger, persistent issues related to social adversity in their lives. This paper draws on findings from the Everyday Legal Problems …

Pedagogy Of The Edges: Anarchism And The Implicate Order, Jenka Soderberg

Leadership for Sustainability Education Comprehensive Papers

The ecological, structural and epistemological crisis that the planet is facing right now cannot be resolved within the modern educational model. Education can be a means for the transformation of society to a more just, sustainable future – but only if education itself is transformed and re-envisioned by looking to the perspectives that have been most marginalized. This new kind of pedagogy will develop outside the realm of an academic discourse, and will be found in transformative social justice movements and the relationships that are formed in these movements.