Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2018

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 37621 - 37650 of 40679

Full-Text Articles in Entire DC Network

Preparation And Characterization Of Starch Films Reinforced With Citrate Cellulose Nanocrystals, Prapaporn Nakarat Jan 2018

Preparation And Characterization Of Starch Films Reinforced With Citrate Cellulose Nanocrystals, Prapaporn Nakarat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Citrate-modified bacterial cellulose nanocrystals (citrate CNCs) were prepared by a green one-pot dual acid (citric and hydrochloric acids) method and used them to reinforce three types of starch films; corn, wheat and rice starch films. The average length and width of citrate CNCs were 583 and 46 nm, respectively. The degree of citrate substitution on CNCs was 0.075 and its crystallinity index was closely to the original bacterial cellulose. The effect of various amount of citrate CNCs (0-20%wt of starch) on film property was study. Three starch films showed the same trend of examination results. The film thickness of most …

Go to article

Surface-Enhanced Raman Scattering Technique For Polycyclic Aromatic Hydrocarbons Detection Using Thiol-Functionalized Silver Nanoparticle Films, Sathita Taksadej Jan 2018

Surface-Enhanced Raman Scattering Technique For Polycyclic Aromatic Hydrocarbons Detection Using Thiol-Functionalized Silver Nanoparticle Films, Sathita Taksadej

Chulalongkorn University Theses and Dissertations (Chula ETD)

The detection of polycyclic aromatic hydrocarbons (PAHs) is developed based on surface-enhanced Raman scattering (SERS) using silver nanoparticle films as SERS substrates. The films are fabricated by a Langmuir Blodgett (LB) method and the surface of AgNP films are functionalized with various types of aromatic and aliphatic thiols, i.e., naphthalenethiol, phenylethanethiol, pentanethiol, octanethiol, and dodecanethiol, to create a hydrophobic layer for PAHs to attach on and stay in hot spot. The results indicate that nine kinds of PAHs with different structures, i.e., anthracene, chrysene, naphthacene, naphthalene, phenanthrene, pentacene, perylene, pyrene, and triphenylene, can attach on the surfaces of thiol-modified AgNP …

Go to article

Improved Barrier Properties Of Pp/Ldpe Composite Film: Effect Of Montmorillonite And Poly (Lactic Acid), Supornpat Mooninta Jan 2018

Improved Barrier Properties Of Pp/Ldpe Composite Film: Effect Of Montmorillonite And Poly (Lactic Acid), Supornpat Mooninta

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this research, the properties of polypropylene (PP) were improved for single layer film application by incorporating low density polyethylene (LDPE), poly(lactic acid) (PLA) and montmorillonite (MMT). The polymer composites was prepared by melt blending using a twin screw extruder and the film was produced by cast film extruder. The addition of LDPE in PP improved the elongation at break and tear strength. The PP/LDPE blend at the ratio of 80:20 (w/w) was selected for blending with PLA and MMT and the PP/LDPE/PLA/MMT composite showed the increased tensile modulus while the elongation at break decreased with increasing PLA and MMT …

Go to article

Adsorption Of Methane And Carbon Dioxide On Activated Carbon And Metal Organic Frameworks, Chutima Sudsuansi Jan 2018

Adsorption Of Methane And Carbon Dioxide On Activated Carbon And Metal Organic Frameworks, Chutima Sudsuansi

Chulalongkorn University Theses and Dissertations (Chula ETD)

Natural gas has gain popularity for transportation among other fuels since it is the cleanest burning fossil fuel. However, the important challenge for utilizing natural gas is its comparatively low volumetric energy storage density. Consequently, a suitable natural gas storage is needed. Adsorbed natural gas (ANG) is an interesting alternative because it could be expected to reduce the cost and potential damage from compressed natural gas (CNG) and liquefied natural gas (LNG) technology. Comparative adsorption of methane and carbon dioxide on activated carbon ZIF-8, UiO-66, and MIL-53 (Al) was investigated at 35 °C and up to 100 psi. The addition …

Go to article

Polyisocyanurate Foams Preparation Catalyzed By Mixtures Of Copper-Amine Complexes/Potassium 2-Ethylhexanoate, Teeraporn Suwannawet Jan 2018

Polyisocyanurate Foams Preparation Catalyzed By Mixtures Of Copper-Amine Complexes/Potassium 2-Ethylhexanoate, Teeraporn Suwannawet

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this research, a new catalyst system for the preparation of polyisocyanurate (PIR) foam was developed. The mixture of copper-amine complex:potassium 2-ethylhexanoate (K-15) and metal-ethanolamine complex:K-15 were used as catalysts. Two copper-amine complexes and two metal-ethanolamine complexes, namely Cu(OAc)2(en)2, Cu(OAc)2(trien), Cu(OAc)2(EA)2 and Zn(OAc)2(EA)2, respectively; where en = ethylene diamine, trien = triethylenetetramine and EA = ethanolamine, were used as catalyst for blowing and gelling reactions. K-15 was used as a catalyst for trimerization reaction. These catalysts could be further used in the preparation of PIR forms without purification. Characterization of catalysts were done by using UV-visible spectroscopy. The factors investigated …

Go to article

Identification Of Crude Oils And Fuel Oils After Weathering Using Biomarkers, Pyrogenic Index And Asphaltenes Contents, Hathairat Thongkorn Jan 2018

Identification Of Crude Oils And Fuel Oils After Weathering Using Biomarkers, Pyrogenic Index And Asphaltenes Contents, Hathairat Thongkorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Oil spills have become a global problem. This is one of the serious problems in marine environment. The spills are generally from reservoir zipping, accident or unauthorized drainage. Typically, the spilled oils are fuel oils or crude oils which are difficult to differentiate. After oil spill incident, oils are undergone weathering processes such as evaporation, dissolution, and biodegradation etc., which are main factor of depleting hydrocarbon. This work focuses on the distribution of hydrocarbon and diagnostic ratio of polycyclic aromatic hydrocarbons such as pristane, phytane, phenanthrene, pyrene, chrysene and biomarker in hopane group after weathering processes. Moreover, measuring of Al, …

Go to article

Heat Exchanger Network Retrofit Under Fouling Effect, Jaturaporn Yanyongsak Jan 2018

Heat Exchanger Network Retrofit Under Fouling Effect, Jaturaporn Yanyongsak

Chulalongkorn University Theses and Dissertations (Chula ETD)

The energy conservation by heat exchanger network (HEN) is important in process design according to an increase of energy costs and global environmental concerns. To minimize the energy consumption with positive net present value (NPV), the retrofitted HEN plays an important role in process energy systems. The HEN retrofit model is based on stage-wise superstructure by Yee and Grossmann (1990). In addition, fouling deposition on the surface area of heat exchangers causes extra energy consumption, production loss and maintenance costs. The new proposed model is retrofitting HEN with fouling effects. This method achieves HEN with the optimal trade-offs between energy …

Go to article

Methane Hydrate Formation And Dissociation : Roles Of Promoters, Kimhak Neak Jan 2018

Methane Hydrate Formation And Dissociation : Roles Of Promoters, Kimhak Neak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Roles of promoters become necessary in methane hydrate formation for the attempt of gas storage application, but some additives might cause unwanted results in gas recovery. The effects of amino acids (l-leucine and l-valine) and surfactants, sodium dodecyl sulfate (SDS), and methyl ester sulfonate (MES) was investigated at 8 MPa and 2 to 4 °C. L-leucine system enhanced hydrate formation because of its surface activity and surface adsorption at interfaces. A noticeable methane uptake yield was also observed in the l-valine solution. Its influences might be from the nature of l-valine that has non-polar, aliphatic hydrophobic side chain resulting in …

Go to article

Optimization Of Single Refrigerant Conocophillips Lng Cascade Process, Naken Saetang Jan 2018

Optimization Of Single Refrigerant Conocophillips Lng Cascade Process, Naken Saetang

Chulalongkorn University Theses and Dissertations (Chula ETD)

An LNG cascade process operates under high pressure and extremely low temperature to liquefy natural gas, requiring very high work input to the compressors. This thesis performed the optimization of the single refrigerant ConocoPhillips LNG process by a global optimization technique based on the domain and image partitioning methodology (Faria and Bagajewicz, 2012) to minimize work input to the system. The procedure consists of an NLP upper bound and MILP lower bound models. The lower bound model was formulated by discretizing and linear relaxation of the upper bound non-linear equations by assigning new integer variables and a set of linear …

Go to article

Energy And Exergy Analysis For Cryogenic Process Design/Retrofit, Nattawat Threerachannarong Jan 2018

Energy And Exergy Analysis For Cryogenic Process Design/Retrofit, Nattawat Threerachannarong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Energy and Exergy analysis are one of alternative techniques to analyze chemical processes in term of energy quality parameters such as enthalpy, entropy and exergetic temperature. The exergetic temperature can conduct Exergy Composite Curves diagram (ECCs) (Marmolejo-Correa, 2012) which represents exergy targets: exergy requirement, exergy rejection and exergy destruction etc. In addition, these targets can be used for improving processes. The strength points of these analysis are to design the new process and to improve the utility performance. Therefore, these analysis methods have been applied to low-temperature process that requires a large amount of energy consumption. In this work, there …

Go to article

Removal Of Mixed Vocs Of Benzene, Toluene And Xylene By A Multistage Corona Discharge System, Nitikorn Ditthawat Jan 2018

Removal Of Mixed Vocs Of Benzene, Toluene And Xylene By A Multistage Corona Discharge System, Nitikorn Ditthawat

Chulalongkorn University Theses and Dissertations (Chula ETD)

The oxidation of mixed volatile organic compounds (VOCs) of benzene, tol-uene and xylene in non-thermal plasma corona discharge was investigated. An initial total VOCs concentration of 100 ppm and feed flow rate of 50.0 ml/min were firstly fixed to investigate the effects of an applied voltage and input frequency on VOCs conversion, power consumption and CO₂ and CO selectivities. For a single stage plasma system, under the optimum applied voltage of 8 kV and input frequency of 500 Hz, the system gave the high CO₂ selectivity with the low CO selectivity and the lowest power consumption. At the optimum operationable …

Go to article

Life Cycle Assessment Of End Of Life Strategies For Waste From Petroleum Production, Nuntawat Urairat Jan 2018

Life Cycle Assessment Of End Of Life Strategies For Waste From Petroleum Production, Nuntawat Urairat

Chulalongkorn University Theses and Dissertations (Chula ETD)

The waste treatment and disposal of oil refining industry sector are one of the significant aspects of environmental concerns. Because they are not only generated in substantial amounts, but also contained with various hazardous substances such as waste oils, spent catalysts, and mercury-contaminated materials. This study aimed to develop and evaluate the waste management strategies, from waste generator (WG) to waste processors (WP), using the material flow analysis (MFA, STAN v.2.6.601) and life cycle assessment (LCA, SimaPro v.8.3.0.0) as an assessment tool. The functional unit is the amount of waste generated from six refineries in the year 2015. The waste …

Go to article

Effecst Of Water On The Methane Hydrate Formation And Dissociation With Hollow Silica And Activated Carbon, Sarocha Rungrussamee Jan 2018

Effecst Of Water On The Methane Hydrate Formation And Dissociation With Hollow Silica And Activated Carbon, Sarocha Rungrussamee

Chulalongkorn University Theses and Dissertations (Chula ETD)

The porous materials, hollow silica (HSC) and activated carbon (AC), were selected to investigate their effects with water on methane hydrate formation and dissociation. The methane hydrate formation with the porous materials was conducted at 8 MPa and 277 K. The dissociation of hydrates was achieved by thermal stimulation with 294 K temperature driving force. The result showed that the hydrate formation of the system with 1:14 HSC to water ratio, the system with excess water, provided the highest methane consumed and water conversion to hydrates. That is because the HSC has low density allowing it to float on water …

Go to article

Heat Exchanger Network Design/Retrofit With Partitioning Technique For Linearization Of Specific Heat Capacity-Temperature Relation, Siwat Valeekiatkul Jan 2018

Heat Exchanger Network Design/Retrofit With Partitioning Technique For Linearization Of Specific Heat Capacity-Temperature Relation, Siwat Valeekiatkul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Heat Exchanger Network (HEN) design has been studied for 40 years starting from heuristic technique; pinch analysis and design method to mathematical programming. The stage-wise superstructure by mathematical programming from Yee and Grossmann (1990) was one of the famous models suitable for industrial HEN design under assumption of constant average specific heat capacity (Cp) which generally should be fitted by empirical form of cubic equation. Zhu and Asante (1999) and Ayotte-Sauvé et al. (2017) used piece-wise linearization called stream segment model, to approximate Cp. Their Cp approximation techniques used high number of piece-wises to calculate Cp accurately. This paper presents …

Go to article

Use Of Binary Surfactant Formulations In Low Ift Foam And Surfactant Flood, Sorrawit Tantipalakul Jan 2018

Use Of Binary Surfactant Formulations In Low Ift Foam And Surfactant Flood, Sorrawit Tantipalakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Viscous fingering and early breakthrough are the main problems observed during the water flooding. These problems could be overcome by using foam flooding by coinjection of surfactant solution and nitrogen gas as a mobility control in a porous media to help improve the sweep efficiency. To gain the maximum benefits of foam flooding, ultra-low interfacial tension foam was studied to obtain a foaming system with high sweep efficiency and at the same time high oil solubilization to help mobilize the oil phase from reservoir rock. In this work, mixed surfactant systems between sodium dioctylsulfosuccinate (AOT) and internal olefin sulfonate (IOS) …

Go to article

Conversion Of N-Pentane To Aromatics: Effect Of Surface Modification By Chemical Liquid Deposition And Promoter Over Nano Scale Ga/Hzsm-5, Sukkatad Sintapanin Jan 2018

Conversion Of N-Pentane To Aromatics: Effect Of Surface Modification By Chemical Liquid Deposition And Promoter Over Nano Scale Ga/Hzsm-5, Sukkatad Sintapanin

Chulalongkorn University Theses and Dissertations (Chula ETD)

This work studied the effects of chemical liquid deposition, i.e., TEOS concentration and multicycle silylation on Ga/HZSM-5 on their catalytic performance in aromatization of n-pentane. The parent nano scale HZSM-5 zeolite catalysts were incorporated with Ga by impregnation method followed by silylation via chemical liquid deposition (CLD) using tetraethyl orthosilicate (TEOS) by varying concentrations and number of cycles. Moreover, the small amount of Pt, Zn, La and P was introduced by co-impregnation method to study the effect of promoter. The physical and chemical properties of catalysts were characterized by N2 physisorption, XRD, NH3-TPD, IPA-TPD, TPO, TPR, SEM and 27Al MAS …

Go to article

Development Of Lcsoft As A Tool For Life Cycle Assessment Of Environmental Impacts : Incorporating Additional Lcia Methodologies And Environmental Footprint, Tanathip Rattanatum Jan 2018

Development Of Lcsoft As A Tool For Life Cycle Assessment Of Environmental Impacts : Incorporating Additional Lcia Methodologies And Environmental Footprint, Tanathip Rattanatum

Chulalongkorn University Theses and Dissertations (Chula ETD)

Life Cycle Assessment (LCA) is a technique to calculate, assess, and analyze environmental impacts through the entire life cycle of products. LCSoft has been continuously developed as LCA software which has ability to integrate with other software e.g. process simulation software and economic analysis software. In addition, LCSoft has several functions which can analyse various environmental effects such as sensitivity analysis, alternative comparison, and eco efficiency analysis. In this thesis, several features were added into LCSoft to cover a wider application range from users and more industrial technologies. This thesis consists of four main parts. First, adding more essential equipment …

Go to article

Furfurylamine-Based Polybenzoxazine Adsorbent For Co2 Capture: Effect Of Carbonization Temperature And Activation Methods, Thanabhumi Vongtiang Jan 2018

Furfurylamine-Based Polybenzoxazine Adsorbent For Co2 Capture: Effect Of Carbonization Temperature And Activation Methods, Thanabhumi Vongtiang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Carbon sorbents are of interest for post-combustion CO₂ capture. Polymers are one of the potential precursors to develop carbon adsorbent with suitable surface functionalities. In this research, furfurylamine-based polybezoxazine was used to produce the carbon adsorbent because of its superior properties such as high char yield, high thermal stability, and low water adsorption. To obtain the carbon adsorbent, benzoxazine monomer was prepared by using furfurylamine, paraformaldehyde, and phenol. Polymerization by a sol-gel technique using xylene as a solvent was employed. The obtained polymer was carbonized at various temperatures: 600, 700, and 800 °C. Physical and chemical activation were then conducted …

Go to article

Development Of Group-Contribution Models For Use In Surfactant Selection - Case Studies Of Single And Mixed Surfactant Applications, Woramet Chanachichalermwong Jan 2018

Development Of Group-Contribution Models For Use In Surfactant Selection - Case Studies Of Single And Mixed Surfactant Applications, Woramet Chanachichalermwong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Microemulsion is the surfactant/oil/water system that is applied to many applications such as enhanced oil recovery, cleaning agents, environmental remediation and drug delivery system. To select the suitable surfactant to form an efficient microemulsion system for each specific condition and application, a systematic selection method is needed to reduce time and valuable resources that may be required in the design of an interest product. This work developed a systematic method to select suitable surfactants for a specific application based on several properties including but not limited to types of emulsion, emulsion stability, solubility and toxicology. Since not all models are …

Go to article

Development Of A Determinant Scale Of Pharmacist’S Care For Herbal And Dietary Supplement Users, Mohd Shahezwan Abd Wahab Jan 2018

Development Of A Determinant Scale Of Pharmacist’S Care For Herbal And Dietary Supplement Users, Mohd Shahezwan Abd Wahab

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: There is a lack of instrument that is valid and reliable to measure the determinant of pharmacist's care (PCare) for herbal and dietary supplement (HDS) users. The present study aimed to develop scales to measure the determinant of PCare for HDS users and to quantify the practices. The study utilized qualitative and quantitative approaches. Methods: Three scales were developed: Direct TPB scale based on a modified Theory of Planned Behaviour (m-TPB) framework, Indirect TPB scale based on the m-TPB and beliefs elicited from community pharmacists (CPs), and PCare-HDS scale based on findings from the qualitative study. This study involved …

Go to article

Taxonomy And Secondary Metabolites Of Selected Endophytic Actinomycete Strains, Nattakorn Kuncharoen Jan 2018

Taxonomy And Secondary Metabolites Of Selected Endophytic Actinomycete Strains, Nattakorn Kuncharoen

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 50 endophytic actinomycetes isolated from fourteen plant species collected from six provinces of Thailand including Bangkok, Chachoengsao, Chiang Mai, Nakhon Pathom, Prachinburi and Suphan Buri were taxonomically studied relied on their phenotypic and chemotaxonomic characteristics, and the 16S rRNA gene sequence analysis. The isolates were identified as members of the family Streptomycetaceae involving Streptomyces (22 isolates), and the family Micromonosporaceae including Micromonospora (25 isolates), Plantactinospora (1 isolate) and Polymorphospora (1 isolate). Based on phenotypic characteristics, whole genome sequence analysis and DNA-DNA hybridization, 5 novel actinomycete species were proposed consisting of Micromonospora globbae (strain WPS1-2T), Micromonospora azadirachtae (strain …

Go to article

Alpha-Glucosidase Inhibitors From Dendrobium Scabrilingue, Chalermporn Sarakulwattana Jan 2018

Alpha-Glucosidase Inhibitors From Dendrobium Scabrilingue, Chalermporn Sarakulwattana

Chulalongkorn University Theses and Dissertations (Chula ETD)

Phytochemical study of the methanol extract of the whole plant of Dendrobium scabrilingue Lindl. (Orchidaceae) resulted in the isolation of a new phenanthrene and a new bisbibenzyl namely dendroscabrols A and B, respectively, along with eight known compounds, identified as (Z)-ferulic acid tetracosyl ester, (E)-ferulic acid tetracosyl ester, gigantol, batatasin III, coelonin, aloifol I, lusianthridin and RF-3192C. The structures of these isolated compounds were determined mainly by spectroscopic data. All isolates were examined for alpha-glucosidase inhibitory activity. Dendroscabrol B and RF-3192C exhibited the most potent activity. In addition, dendroscabrol A, gigantol, coelonin and lusianthridin displayed strong activity compared with the …

Go to article

Neuroprotective Effects Of The Standardized Extract Of Centella Asiatica Eca233 In Rotenone-Induced Parkinson’S Disease Model, Narudol Teerapattarakan Jan 2018

Neuroprotective Effects Of The Standardized Extract Of Centella Asiatica Eca233 In Rotenone-Induced Parkinson’S Disease Model, Narudol Teerapattarakan

Chulalongkorn University Theses and Dissertations (Chula ETD)

The standardized extract of Centella asiatica ECa233 consists of asiaticoside and madecassoside. Previous studies reported various pharmacological effects of, ECa233, especially in the central nervous system disorders. The present study aimed to investigate the neuroprotective effects and protective mechanisms of ECa233 against rotenone-induced neurotoxicity in rats and in neuroblastoma SH-SY5Y cells. In animal study, male Wistar rats were divided into five experimental groups (n=10); control, PD, PD-ECa10, PD-ECa30, and PD-EC100. On days 1-20, control and PD rats received 0.5% carboxymethylcellulose (CMC) (1 mL/kg, p.o.) while ECa233 10, 30 and 100 mg/kg (p.o.) were given to PD-ECa10, PD-ECa30, and PD-EC100, respectively. …

Go to article

Protective Effects Of Eriodictyol On Hydrogen Peroxide-Induced Cell Death In Sh-Sy5y Cells, Saowarose Thongin Jan 2018

Protective Effects Of Eriodictyol On Hydrogen Peroxide-Induced Cell Death In Sh-Sy5y Cells, Saowarose Thongin

Chulalongkorn University Theses and Dissertations (Chula ETD)

Oxidative stress and mitochondrial dysfunction are the major causes of neuronal death in neurodegenerative disorders. Eriodictyol is a flavonoid extracted from the whole plant of Dendrobium ellipsophyllum (thai name: Ueang Thong). The antioxidant and anti-inflammatory effects of eriodictyol have been widely reported. The present study aimed to investigate the protective effect and mechanisms of eriodictyol on hydrogen peroxide (H2O2)-induced cell death in human neuroblastoma SH-SY5Y cells. The protective effect of eriodictyol on cytotoxicity induced by H2O2 was evaluated using resazurin assay. The effects on intracellular reactive oxygen species (ROS) and mitochondria membrane potential were evaluated by 2´-7’ dichlorodihydrofluorescein diacetate (DCFH-DA) …

Go to article

Novel Regulatory Mechanisms Of Protein Kinase B On Apoptosis Susceptibility And Cancer Dedifferentiation, Arnatchai Maiuthed Jan 2018

Novel Regulatory Mechanisms Of Protein Kinase B On Apoptosis Susceptibility And Cancer Dedifferentiation, Arnatchai Maiuthed

Chulalongkorn University Theses and Dissertations (Chula ETD)

No abstract provided.

Go to article

Pharmacokinetic Study Of Cucurbitacin B From Trichosanthes Cucumerina L. In Rats, Natthaphon Hunsakunachai Jan 2018

Pharmacokinetic Study Of Cucurbitacin B From Trichosanthes Cucumerina L. In Rats, Natthaphon Hunsakunachai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cucurbitacin B is a triterpenoid, majorly found in Cucurbitaceae family, particularly in the Trichosanthes cucumerina L. fruits. The pharmacological properties of cucurbitacin B have been studied for decades, particularly an anti-tumor and anti-inflammatory activity. However, the pharmacokinetic profile of this compound is still limited and the investigation is needed for further pharmaceutical product development. This study aimed to investigate the pharmacokinetic profile of cucurbitacin B after administering the compound at different doses and routes to the rats. Male Wistar rats, weighed approximately 400-500 g, were treated with cucurbitacin B extracted from Trichosanthes cucumerina L. The cucurbitacin B was administered at …

Go to article

Association Of Genetic And Non-Genetic Factors With Clinical Responses Of Donepezil And Galantamine In Thai Patients With Dementia, Thitipon Yaowaluk Jan 2018

Association Of Genetic And Non-Genetic Factors With Clinical Responses Of Donepezil And Galantamine In Thai Patients With Dementia, Thitipon Yaowaluk

Chulalongkorn University Theses and Dissertations (Chula ETD)

Donepezil and galantamine are commonly prescribed for the treatment of dementia. However, the response rate of acetylcholinesterase inhibitors is only 15-35 %. Inter-individual variability in donepezil and galantamine response has been associated with genetic factor in some population. Moreover, non-genetic factors such as age, gender, education level, comorbidities and drug-drug interactions can influence pharmacokinetic profiles and drug responses. Therefore, this study aims to investigate the association of genetic variations that involved therapeutic effects of donepezil and galantamine including pathogenic gene; APOE, drug metabolizing genes; CYP2D6, CYP3A5, UGT1A1, transporter gene; ABCB1 and non-genetic factors with therapeutic outcomes as measured as Thai …

Go to article

Consciousness Eliminated In Daniel Dennett, Jittiwat Narakornpaichit Jan 2018

Consciousness Eliminated In Daniel Dennett, Jittiwat Narakornpaichit

Chulalongkorn University Theses and Dissertations (Chula ETD)

One of the major debates in philosophy of mind is the complication about how to explain the manifestation of qualia in the scientific image. Qualia have usually been understood as phenomenal properties of mental states; and their resistance against physical explanation is famously demonstrated by Joseph Levine as the explanatory gap and by David Chalmers as the hard problem of consciousness. The aim of this thesis is to study and evaluate Daniel Dennett's response to the complication in this debate with his eliminativist approach on consciousness. The key idea of Dennett's so-called illusionism is that qualia only seem to exist …

Go to article

Cross-Cultural Adaptation And Psychometric Properties Of The Thai Version Of The Patient-Reported Outcomes Measurement Information System-29 (Promis-29), Polake Rawang Jan 2018

Cross-Cultural Adaptation And Psychometric Properties Of The Thai Version Of The Patient-Reported Outcomes Measurement Information System-29 (Promis-29), Polake Rawang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Abstract Purpose To culturally adapt the Patient-Reported Outcomes Measurement Information System-29 into Thai (T-PROMIS-29) and evaluate the reliability and validity of the culturally adapted questionnaire. Methods The translation was performed using the Functional Assessment of Chronic Illness Therapy (FACIT) translation guidelines. Internal consistency and test-retest reliability at a 1-week interval for the translated measure were computed. Construct validity was evaluated by computing correlations between the T-PROMIS-29 scores and selected SF-36 and Fear Avoidance Belief Questionnaire (FABQ) scale scores for both convergent and discriminant validity. Results The study sample comprised of 241 participants with chronic low back pain. Internal consistencies were …

Go to article

Effect Of Cu(In,Ga)₃Se₅ Ultra-Thin Layer On Optical Properties And Photovoltaic Efficiency Of Cu(In,Ga)Se₂ Thin Film Solar Cells, Boonyaluk Namnuan Jan 2018

Effect Of Cu(In,Ga)₃Se₅ Ultra-Thin Layer On Optical Properties And Photovoltaic Efficiency Of Cu(In,Ga)Se₂ Thin Film Solar Cells, Boonyaluk Namnuan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cu(In,Ga)3Se5 (135-CIGS) layers with various thicknesses were deposited on the surface of ~1.8 micron thick Cu(In,Ga)Se2 (112-CIGS) photon absorber in the fabrication of CIGS thin film solar cells. This significantly affects the shift of the optical band gap energy from 1.15 eV (112-CIGS) to 1.19 eV, with only 10 nm thick of 135-CIGS capping layer, leading to the increase in the open-circuit voltage (Voc) of the solar cells. The optical transmission spectra show no sign of separated 135-CIGS layer. The maximum Voc of 670 mV is obtained from 5-10 nm thick 135-CIGS capping layer on 112-CIGS compared to 646 mV …

Go to article

First Prev Next Last