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2018

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Evidence That A Partner-Switching Regulatory System Modulates Hormogonium Motility In The Filamentous Cyanobacterium Nostoc Punctiforme, Kelsey Wynne Riley Jan 2018

Evidence That A Partner-Switching Regulatory System Modulates Hormogonium Motility In The Filamentous Cyanobacterium Nostoc Punctiforme, Kelsey Wynne Riley

University of the Pacific Theses and Dissertations

Partner-switching regulatory systems (PSRSs) are utilized by many different bacteria to regulate a wide array of cellular responses, from stress response to expression of virulence factors. The filamentous cyanobacterium Nostoc punctiforme can transiently differentiate motile filaments, called hormogonia, in response to various changes in the environment. Hormogonia utilize a Type IV pilus (T4P) complex in conjunction with a secreted polysaccharide for gliding motility along solid surfaces. This study identified three genes, designated hmpU, hmpW, and hmpV, encoding the protein components of a PSRS involved in regulation of hormogonium motility in N. punctiforme. Although mutant strains with in-frame deletions in hmpU, …


The Influences Of A Mariachi Education On Student Perceptions Of Academic Achievement, Academic Attainment, And Student Engagement, Victoria Lynn Smith Jan 2018

The Influences Of A Mariachi Education On Student Perceptions Of Academic Achievement, Academic Attainment, And Student Engagement, Victoria Lynn Smith

University of the Pacific Theses and Dissertations

The purpose of this research study is to examine the influences of mariachi education on student perceptions of their academic achievement, academic attainment, and student engagement. The study involved students attending schools in California, Oregon, and Texas with mariachi programs that consented to be a part of the study, whose districts approved their participation. The students were approached to participate in this study, as they are a part of their school’s mariachi program in middle or high school throughout the Western half of the United States. A convergent parallel (mixed-methods) design and descriptive statistical analyses were used to investigate the …


Applications Of Low Field Magnetic Resonance Imaging, Muhammad Waqas Jan 2018

Applications Of Low Field Magnetic Resonance Imaging, Muhammad Waqas

University of the Pacific Theses and Dissertations

Magnetic resonance imaging is a non-invasive imaging modality that is used to produce detailed images of soft tissues within the human body. Typically, MRI scanners used in the clinical setting are high field systems because they have a magnetic field strength greater than 1.5 Tesla. The high magnetic field offers the benefit of high spatial resolution and high SNR. However, low filed systems can also produce high resolution MR images with the added benefit of imaging stiffer samples. In this study, a low field 0.5 T MR system was used to image various samples to demonstrate the capability of the …


Rational Design Of Peptides Binding Towards Human Pd-L1 Using Knob-Socket Model, Xingchen Zha Jan 2018

Rational Design Of Peptides Binding Towards Human Pd-L1 Using Knob-Socket Model, Xingchen Zha

University of the Pacific Theses and Dissertations

Programmed death-ligand 1 (PD-L1) is a type 1 transmembrane protein that has been reported to play a vital role in mediating suppressed immunity. The interaction between PD-L1 and PD-1 delivers a negative signal that reduces the proliferation of these T cells and induces apoptosis at the same time. Antibodies that can block the Programmed death-ligand 1 (PD-L1) on tumor cells have been shown to alleviate cancer-induced immunosuppression. While antibodies have a great potential in various therapeutic uses, many drawbacks such as the high cost of production, huge molecular size, and poor permeability impose restrictions on the extensive use of full-length …


Computational Methods In Biomolecules:Study Of Hydrophilic Interactions In Protein Folding & Constant-Ph Molecular Simulation Of Ph Sensitive Lipid Morc16, Wei Zhang Jan 2018

Computational Methods In Biomolecules:Study Of Hydrophilic Interactions In Protein Folding & Constant-Ph Molecular Simulation Of Ph Sensitive Lipid Morc16, Wei Zhang

University of the Pacific Theses and Dissertations

Water molecules play a significant role in biological process and are directly involved with bio-molecules and organic compounds and ions. Recent research has focused on the thermal dynamics and kinetics of water molecules in solution, including experimental (infrared spectroscopy and Raman spectroscopy) and computational (Quantum Mechanics and Molecular Dynamics) approaches. The reason that water molecules are so unique, why they have such a profound influence on bio-activity, why water molecules show some anomalies compared to other small molecules, and where and how water molecules exert their influence on solutes are some of the areas under study. We studied some properties …


The Implementation And Adoptability Of Behavioral Skills Training In A Career Center, Vinthia Wiryananda Wirantana Jan 2018

The Implementation And Adoptability Of Behavioral Skills Training In A Career Center, Vinthia Wiryananda Wirantana

University of the Pacific Theses and Dissertations

It is unclear if staff at career centers use, or are willing to use, empirically-supported procedures like behavioral skills training (BST) when teaching interview skills to college students. The purpose of this study was to assess the extent to which the typical career center training consisted of BST, to evaluate staff-implemented BST, and to measure student performance as a result of both training. Using non-concurrent multiple baseline design, three staff were taught to use BST to teach three students to answer interview questions. First, staff used their typical training procedure, and then, they used BST to teach student interview skills; …


Comparing Equivalence-Based Instruction With Lecture-Based Instruction To Teach College Students To Identify Logical Fallacies, Kelly Roughgarden Jan 2018

Comparing Equivalence-Based Instruction With Lecture-Based Instruction To Teach College Students To Identify Logical Fallacies, Kelly Roughgarden

University of the Pacific Theses and Dissertations

Educators and practicing professionals in many fields emphasize the importance of critical thinking for effective decision-making. However, critical thinking skills are not usually directly taught in traditional educational settings. A subset of these skills, identifying logical fallacies, could be amenable to direct instruction using procedures that establish conditional discriminations, such as equivalence-based instruction (EBI). EBI procedures have been shown to be effective and efficient when teaching a variety of skills, including the identification of logical fallacies, when compared with no-instruction and self-instruction control groups. The purpose of this study is to compare the effectiveness of web-based EBI procedures to a …


Shape From Focus Image Processing Approach Based 3d Model Construction Of Manufactured Part, Mitchel Wendland Jan 2018

Shape From Focus Image Processing Approach Based 3d Model Construction Of Manufactured Part, Mitchel Wendland

University of the Pacific Theses and Dissertations

The purpose of this research is to develop a process and an algorithm to create a 3D model of the surface a part. This is accomplished using a single camera and a CNC machine as a movable stage. A gradient based focus measure operator written in MATLAB is used to process the images and to generate the surface model. The scopes of this research are image processing and surface model generation as well as verifying part accuracy. The algorithm is able to create a rough surface model of a photographed part, and with careful calibration in a limited number of …


Influence Of Dietary Nitrate Supplementation On Local Sweating And Cutaneous Vascular Responses During Exercise In A Hot Environment., T Amano, D Okushima, Bc Breese, S Bailey, S Koga, N Kondo Jan 2018

Influence Of Dietary Nitrate Supplementation On Local Sweating And Cutaneous Vascular Responses During Exercise In A Hot Environment., T Amano, D Okushima, Bc Breese, S Bailey, S Koga, N Kondo

School of Biomedical Sciences

No abstract provided.


Prevention Of Tuberculosis In Rhesus Macaques By A Cytomegalovirus-Based Vaccine, Scott G. Hansen, Daniel E. Zak, Guangwu Xu, Julia C. Ford, Emily E. Marshall, Daniel Malouli, Roxanne M. Gilbride, Colette M. Hughes, Abigail B. Ventura, Emily Ainslie, Kurt T. Randall, Andrea N. Selseth, Parker Rundstrom, Lauren Herlache, Matthew S. Lewis, Haesun Park, Shannon L. Planer, John M. Turner, Miranda Fischer, Christina Armstrong, Robert C. Zweig, Joseph Valvo, Jackie M. Braun, Smitha Shankar, Lenette Lu, Andrew W. Sylwester, Alfred W. Legasse, Martin Messerle, Michael A. Jarvis, Michael A. Jarvis, Alan Aderem, Galit Alter, Dominick J. Laddy, Michele Stone, Aurelio Bonavia, Thomas G. Evans, Michael K. Axthelm, K Fruh, Paul T. Edlefsen, Louis J. Picker Jan 2018

Prevention Of Tuberculosis In Rhesus Macaques By A Cytomegalovirus-Based Vaccine, Scott G. Hansen, Daniel E. Zak, Guangwu Xu, Julia C. Ford, Emily E. Marshall, Daniel Malouli, Roxanne M. Gilbride, Colette M. Hughes, Abigail B. Ventura, Emily Ainslie, Kurt T. Randall, Andrea N. Selseth, Parker Rundstrom, Lauren Herlache, Matthew S. Lewis, Haesun Park, Shannon L. Planer, John M. Turner, Miranda Fischer, Christina Armstrong, Robert C. Zweig, Joseph Valvo, Jackie M. Braun, Smitha Shankar, Lenette Lu, Andrew W. Sylwester, Alfred W. Legasse, Martin Messerle, Michael A. Jarvis, Michael A. Jarvis, Alan Aderem, Galit Alter, Dominick J. Laddy, Michele Stone, Aurelio Bonavia, Thomas G. Evans, Michael K. Axthelm, K Fruh, Paul T. Edlefsen, Louis J. Picker

School of Biomedical Sciences

No abstract provided.


Foxn1-Dependent Thymic Epithelial Cells Promote T-Cell Leukemia Development, Marinella N. Ghezzo, Mónica T. Fernandes, Ivette Pacheco-Leyva, Pedro M. Rodrigues, Rui S. Machado, Mas Araujo, Ravi K. Kalathur, Matthias E. Futschik, Nuno L. Alves, Santos Nr Dos Jan 2018

Foxn1-Dependent Thymic Epithelial Cells Promote T-Cell Leukemia Development, Marinella N. Ghezzo, Mónica T. Fernandes, Ivette Pacheco-Leyva, Pedro M. Rodrigues, Rui S. Machado, Mas Araujo, Ravi K. Kalathur, Matthias E. Futschik, Nuno L. Alves, Santos Nr Dos

School of Biomedical Sciences

No abstract provided.