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2018

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Improved Reference Genome For The Domestic Horse Increases Assembly Contiguity And Composition, Theodore S. Kalbfleisch, Edward S. Rice, Michael S. Depriest Jr., Brian P. Walenz, Matthew S. Hestand, Joris R. Vermeesch, Brendan L. O'Connell, Ian T. Fiddes, Alisa O. Vershinina, Nedda F. Saremi, Jessica L. Petersen, Carrie J. Finno, Rebecca R. Bellone, Molly E. Mccue, Samantha A. Brooks, Ernest Bailey, Ludovic Orlando, Richard E. Green, Donald C. Miller, Douglas F. Antczak, James N. Macleod Jan 2018

Improved Reference Genome For The Domestic Horse Increases Assembly Contiguity And Composition, Theodore S. Kalbfleisch, Edward S. Rice, Michael S. Depriest Jr., Brian P. Walenz, Matthew S. Hestand, Joris R. Vermeesch, Brendan L. O'Connell, Ian T. Fiddes, Alisa O. Vershinina, Nedda F. Saremi, Jessica L. Petersen, Carrie J. Finno, Rebecca R. Bellone, Molly E. Mccue, Samantha A. Brooks, Ernest Bailey, Ludovic Orlando, Richard E. Green, Donald C. Miller, Douglas F. Antczak, James N. Macleod

Department of Animal Science: Faculty Publications

Recent advances in genomic sequencing technology and computational assembly methods have allowed scientists to improve reference genome assemblies in terms of contiguity and composition. EquCab2, a reference genome for the domestic horse, was released in 2007. Although of equal or better quality compared to other first-generation Sanger assemblies, it had many of the shortcomings common to them. In 2014, the equine genomics research community began a project to improve the reference sequence for the horse, building upon the solid foundation of EquCab2 and incorporating new short-read data, long-read data, and proximity ligation data. Here, we present EquCab3. The count of …


Genome-Wide Association Study Of Stayability And Heifer Pregnancy In Red Angus Cattle, S. E. Speidel, B. A. Buckley, R. J. Boldt, R. M. Enns, J. Lee, Matthew L. Spangler, M. G. Thomas Jan 2018

Genome-Wide Association Study Of Stayability And Heifer Pregnancy In Red Angus Cattle, S. E. Speidel, B. A. Buckley, R. J. Boldt, R. M. Enns, J. Lee, Matthew L. Spangler, M. G. Thomas

Department of Animal Science: Faculty Publications

Reproductive performance is the most important component of cattle production from the standpoint of economic sustainability of commercial beef enterprises. Heifer Pregnancy (HPG) and Stayability (STAY) genetic predictions are 2 selection tools published by the Red Angus Association of America (RAAA) to assist with improvements in reproductive performance. Given the importance of HPG and STAY to the profitability of commercial beef enterprises, the objective of this study was to identify QTL associated with both HPG and STAY in Red Angus cattle. A genome-wide association study (GWAS) was performed using deregressed HPG and …


Genome-Wide Association Study For Feed Efficiency Traits Using Snp And Haplotype Models, Kashly Rene Schweer, Stephen D. Kachman, Larry A. Kuehn, Harvey Freetly, John E. Pollak, Matthew L. Spangler Jan 2018

Genome-Wide Association Study For Feed Efficiency Traits Using Snp And Haplotype Models, Kashly Rene Schweer, Stephen D. Kachman, Larry A. Kuehn, Harvey Freetly, John E. Pollak, Matthew L. Spangler

Department of Animal Science: Faculty Publications

Feed costs comprise the majority of variable expenses in beef cattle systems making feed efficiency an important economic consideration within the beef industry. Due to the expense of recording individual feed-intake phenotypes, a genomic-enabled approach could be advantageous toward improving this economically relevant trait complex. A genome-wide association study (GWAS) was performed using 748 crossbred steers and heifers representing seven sire breeds with phenotypes for ADG and ADFI. Animals were genotyped with the BovineSNP50v2 BeadChip containing approximately 54,000 SNP. Both traits were analyzed using univariate SNPbased (BayesC) and haplotype-based (BayesIM) models and jointly using BayesIM to perform a bivariate GWAS. …


Risks Associated To Different Methods Of Increasing Pregnancy Rate Of Cows In Cow-Calf Systems, Tamara Esteves De Oliveira, Julio Otavio Jardim Barcellos, Jack Whittier, Odilene De Souza Teixeira, David Santos De Freitas, Ricardo Pedroso Oaigen, Matheus Dhein Dill, Concepta Mcmanus Jan 2018

Risks Associated To Different Methods Of Increasing Pregnancy Rate Of Cows In Cow-Calf Systems, Tamara Esteves De Oliveira, Julio Otavio Jardim Barcellos, Jack Whittier, Odilene De Souza Teixeira, David Santos De Freitas, Ricardo Pedroso Oaigen, Matheus Dhein Dill, Concepta Mcmanus

Department of Animal Science: Faculty Publications

This study assessed the risks of different management practices to increase pregnancy rate in beef cow-calf systems, aiming at assisting decision-making. The perception of 18 experts on animal sciences regarding the risks of 32 nutritional, breeding, and general management practices applied to increase pregnancy rate were evaluated through questionnaires. The experts were selected by a non-probability sampling of researchers on veterinary and animal sciences. In addition, five farmers and eight technical consultants were also selected. The questionnaire was applied during a face-to-face meeting. The risk of each practice was assessed according to four factors, namely, cost, technical knowledge, operational complexity, …


Rumen Bacterial Composition In Lambs Is Affected By Β-Adrenergic Agonist Supplementation And Heat Stress At The Phylum Level, Erin M. Duffy, Shauna M. Tietze, Allison L. Knoell, Nirosh D. Aluthge, Samodha C. Fernando, Ty B. Schmidt, Dustin T. Yates, Jessica L. Petersen Jan 2018

Rumen Bacterial Composition In Lambs Is Affected By Β-Adrenergic Agonist Supplementation And Heat Stress At The Phylum Level, Erin M. Duffy, Shauna M. Tietze, Allison L. Knoell, Nirosh D. Aluthge, Samodha C. Fernando, Ty B. Schmidt, Dustin T. Yates, Jessica L. Petersen

Department of Animal Science: Faculty Publications

The rumen has several important physiological functions, including absorption, transport, metabolic activity, and host protection (Roh et al., 2007). The rumen is extensively researched due to the importance of ruminants in agriculture and the major role played by rumen microbes in nutrient utilization and health of the ruminant animal. The microbial community of the rumen is altered by diet (McCann et al., 2014), age (Jami et al., 2013), and environment.


Chronic Maternal Inflammation During Late Gestation Impairs Subsequent Β-Cell Function But Not Islet Growth In Fetal Sheep, M.D. Abebe, C.N. Cadaret, T.B. Barnes, K.A. Beede, D. T. Yates Jan 2018

Chronic Maternal Inflammation During Late Gestation Impairs Subsequent Β-Cell Function But Not Islet Growth In Fetal Sheep, M.D. Abebe, C.N. Cadaret, T.B. Barnes, K.A. Beede, D. T. Yates

Department of Animal Science: Faculty Publications

Intrauterine growth restriction (IUGR) greatly increases perinatal mortality and morbidity rates, and leads to much greater risk for metabolic complications later in life. One such complication is the development of glucose intolerance or diabetes, which typically develops concurrently with abhorrent patterns of insulin secretions due to diminished β-cell mass and impaired function as well as an overall reduction in pancreatic endocrine tissue. The mechanisms by which IUGR causes problems with health and function of the pancreatic islets are not well understood. Therefore, our goal for this study was to determine how materno-fetal inflammation (MI) affects β-cell growth and function. To …


Research Note Prediction Model For Manure Zinc Excretion In Laying Hens, Kelli M. Martin, N. Vargas-Jurado, S. E. Purdum Jan 2018

Research Note Prediction Model For Manure Zinc Excretion In Laying Hens, Kelli M. Martin, N. Vargas-Jurado, S. E. Purdum

Department of Animal Science: Faculty Publications

The objective of this research trial was to compare 2 sources of zinc and different levels of supplementation on manure zinc excretion in laying hens. Bovan White Leghorn hens were used in this study and fed one of 6 dietary treatments. Treatments were in a 2 × 3 factorial arrangement with 2 sources of zinc (zinc sulfate or Availa R < Zn) and 3 levels (40, 80, or 120 ppm) and were randomly assigned to 48 cages with 5 hens/cage and 8 replicates/treatment. Hens were housed in a tiered manure-belt housing system providing 627.1 cm2/hen and were given access to 110 g/hen/d of feed. Manure samples were collected, and manure zinc content was calculated at 10- week intervals. Data were analyzed using the Glimmix procedure in SAS. There was a significant overall effect of source (P < 0.0001) for zinc content, such that hens fed zinc sulfate had lower amounts of zinc excretion. There was also a significant level effect (P < 0.0001) in which hens fed 120 ppm zinc excreted the greatest amount of zinc. A significant source by level interaction was observed (P < 0.0001) for both the overall and individual analyses, such that 120 ppm Availa R < Zn showed the highest zinc excretion, and both 40 ppm zinc sulfate and Availa R < Zn showed the lowest zinc excretion. Based on these results, a prediction equation was written for an estimated amount of zinc excretion based on the amount of zinc provided in the diet.


Shinyaim: Shiny‐Based Application Of Interactive Manhattan Plots For Longitudinal Genome‐Wide Association Studies, Waseem Hussain, Malachy T. Campbell, Harkamal Walia, Gota Morota Jan 2018

Shinyaim: Shiny‐Based Application Of Interactive Manhattan Plots For Longitudinal Genome‐Wide Association Studies, Waseem Hussain, Malachy T. Campbell, Harkamal Walia, Gota Morota

Department of Animal Science: Faculty Publications

Owning to advancements in sensor‐based, non‐destructive phenotyping platforms, researchers are increasingly collecting data with higher temporal resolution. These phenotypes collected over several time points are cataloged as longitudinal traits and used for genome‐wide association studies (GWAS). Longitudinal GWAS typically yield a large number of output files, posing a significant challenge to data interpretation and visualization. Efficient, dynamic, and integrative data visualization tools are essential for the interpretation of longitudinal GWAS results for biologists; however, these tools are not widely available to the community. We have developed a flexible and user‐friendly Shiny‐based online application, ShinyAIM, to dynamically view and interpret temporal …


Understanding Streaming And Copyright: A Comparison Of The United States And European Regimes, Thomas Y. Lu Jan 2018

Understanding Streaming And Copyright: A Comparison Of The United States And European Regimes, Thomas Y. Lu

Journal of Business & Technology Law

No abstract provided.


Effects Of Music Therapy On Individuals With Dementia: An Intergrative Literature Review, Liani Sanchez Jan 2018

Effects Of Music Therapy On Individuals With Dementia: An Intergrative Literature Review, Liani Sanchez

Honors Undergraduate Theses

The purpose of this integrative review was to examine the effects of music therapy, a complementary intervention, on individuals with dementia. Peer-reviewed journals were retrieved from MEDLINE, CINAHL, CINAHL Plus with Full Text, Cochrane Central Register of Controlled Trials, Music Index to evaluate their relevance to music therapy use in people diagnosed with dementia. English and Spanish-language research articles published from 2000-2017 were included for the review (n=15). The literature indicates the use of music therapy as an adjuvant therapy for the treatment of dementia in older adults may be beneficial in decreasing symptoms of aggression, anxiety, agitation and depression. …


An Exploration Of Representations Of Race And Ethnicity In Three Transitional Series For Young Children, Sonia M. Balkaran Jan 2018

An Exploration Of Representations Of Race And Ethnicity In Three Transitional Series For Young Children, Sonia M. Balkaran

Honors Undergraduate Theses

This thesis seeks to explore the related research literature surrounding representations and portrayals of protagonists of various multicultural backgrounds in series or transitional books. As teachers, it is essential to acknowledge the lack of multicultural characters in children's literature among elementary classroom bookshelves and learn how to incorporate literature featuring strong main characters of varying races and ethnicities so that children can see role models who mirror their own contexts. Prior studies, such as Gangi (2008) and Green and Hopenwasser (2017) have examined the deficiency of multicultural literature in the classroom, particularly among transitional stories, which shows the importance of …


Categorizing Student Speech, Alexander Tsesis Jan 2018

Categorizing Student Speech, Alexander Tsesis

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


The Legal Implications Of The Metoo Movement, Elizabeth C. Tippett Jan 2018

The Legal Implications Of The Metoo Movement, Elizabeth C. Tippett

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Left To Languish: The Importance Of Expanding The Due Process Rights Of Immigration Detainees, Maisie A. Baldwin Jan 2018

Left To Languish: The Importance Of Expanding The Due Process Rights Of Immigration Detainees, Maisie A. Baldwin

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Mayo, Myriad, And A Muddled Analysis: Do Recent Changes To The Patentable Subject Matter Doctrine Threaten Patent Protections For Epigenetics-Based Inventions?, Mike Sikora Jan 2018

Mayo, Myriad, And A Muddled Analysis: Do Recent Changes To The Patentable Subject Matter Doctrine Threaten Patent Protections For Epigenetics-Based Inventions?, Mike Sikora

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


What Makes Ensuring Access To Affordable Prescription Drugs The Hardest Problem In Health Policy?, Michelle M. Mello Jan 2018

What Makes Ensuring Access To Affordable Prescription Drugs The Hardest Problem In Health Policy?, Michelle M. Mello

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Dangerous Times: The Fda's Role In Information Production, Past And Future, Amy Kapczynski Jan 2018

Dangerous Times: The Fda's Role In Information Production, Past And Future, Amy Kapczynski

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Regulatory Silence At The Fda, Jordan Paradise Jan 2018

Regulatory Silence At The Fda, Jordan Paradise

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Drug Approval In A Learning Health System, W. Nicholson Price Ii Jan 2018

Drug Approval In A Learning Health System, W. Nicholson Price Ii

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


The Morality Of Compulsory Licensing As An Access To Medicines Tool, Margo A. Bagley Jan 2018

The Morality Of Compulsory Licensing As An Access To Medicines Tool, Margo A. Bagley

Minnesota Law Review, Vols. 1-106:1 (1917-2021)

No abstract provided.


Reasoning Through Clashes Between Religion And Equality: Case Law, Skeptics, And Social Coherence, Michael A. Helfand Jan 2018

Reasoning Through Clashes Between Religion And Equality: Case Law, Skeptics, And Social Coherence, Michael A. Helfand

Constitutional Commentary, Vols 1–36 (1984–2022)

No abstract provided.


Modeling Pre-Settlement Wetlands In Northern Minnesota, Johnathon T. Salfer Jan 2018

Modeling Pre-Settlement Wetlands In Northern Minnesota, Johnathon T. Salfer

All Graduate Theses, Dissertations, and Other Capstone Projects

Modern land use has dramatically altered the native landscape across much of Minnesota and the United States. “Manifest Destiny” has ingrained the idea in American society that wetlands and related lands of “low value” need to be tamed and made profitable. In many places, wetlands have been drained and removed so that agriculture can take over. In recent years, people have begun to see the unintended consequences of this method, and importance is now being given to natural wetlands through various government projects and programs. Using National Wetlands Inventory (NWI) data, Drainage Index (DI) values calculated from Soil Survey Geographic …


Across An Ecotone: An Analysis Of Late Prehistoric Artifacts From Southern Minnesota, Jamison M. Jordan Jan 2018

Across An Ecotone: An Analysis Of Late Prehistoric Artifacts From Southern Minnesota, Jamison M. Jordan

All Graduate Theses, Dissertations, and Other Capstone Projects

The transition zone between the Plains and Woodlands in Southern Minnesota is not homogenous, neither in terms of ecology or culture. The deciduous forests and oak barrens of the Eastern Woodlands present an ecological environment with a resource base much different than the tallgrass prairies of the Northeastern Plains, and the material remains left behind by peoples inhabiting both areas reflected this. Subjects such as the exchange of technology, such as one culture adopting select tools or traits from populations living on the other side of the ecotone, as well as the movement of people in general across this particular …


Making Sense Of Equality, Mark D. Rosen Jan 2018

Making Sense Of Equality, Mark D. Rosen

Constitutional Commentary, Vols 1–36 (1984–2022)

Book Review Symposium: One Another's Equals: The Basis of Human Equality


Echoes Of Slavery Ii: How Slavery's Legacy Distorts Democracy, Juan F. Perea Jan 2018

Echoes Of Slavery Ii: How Slavery's Legacy Distorts Democracy, Juan F. Perea

Faculty Publications & Other Works

No abstract provided.


One Fragment At A Time: The Literature Of Deborah Miranda And Wendy Rose, Kristin Leonard Jan 2018

One Fragment At A Time: The Literature Of Deborah Miranda And Wendy Rose, Kristin Leonard

Journal of South Texas English Studies

No abstract provided.


Style In Scientific Writing, Caitlin Geoghan Jan 2018

Style In Scientific Writing, Caitlin Geoghan

Open Educational Resources

No abstract provided.


The American Black Body: Materials,Symbols, And Representations From A Perceived African American, Christopher Santos Jan 2018

The American Black Body: Materials,Symbols, And Representations From A Perceived African American, Christopher Santos

Electronic Theses and Dissertations

As a Cape Verdean American, I investigate the idea of what it means to be of the African Diaspora in America. I also consider the experiences of past generations of American black bodies and how their history has molded my world. This series of work began with Mask Drawing 1, an ink drawing inspired by my own interpretation of an African mask. Subjected to colorism, the discrimination of a person based on their skin color, my skin was not enough validation for other people to view me as black. On numerous occasions I have had to clarify my identity, nationality …


Momentum, Moment, Epiphany: The Psychological Intersection Of Motion Picture, The Still Frame, And Three-Dimensional Form, Mark Gerstein Jan 2018

Momentum, Moment, Epiphany: The Psychological Intersection Of Motion Picture, The Still Frame, And Three-Dimensional Form, Mark Gerstein

Electronic Theses and Dissertations

My journey from Hollywood Film production to a Fine Arts practice has been shaped by theory from Philosophy of Mind, Cognitive Psychology, Film, and Art, leading me to a new visual vocabulary at the intersection of motion picture, the still image, and three-dimensional form. I create large mixed media collages by projecting video onto photographs and sculptural forms, breaking the boundaries of the conventional film frame and exceeding the dynamic range of typical visual experience. My work explores emotional connections and fissures within family, and hidden meanings of haunting memories and familiar places. I am searching for an elusive type …


To The Memory Of Brave Men: The Imperial War Graves Commission And India's Missing Soldiers Of The First World War, Roger Sims Jan 2018

To The Memory Of Brave Men: The Imperial War Graves Commission And India's Missing Soldiers Of The First World War, Roger Sims

Electronic Theses and Dissertations

This thesis examines the commemoration of Indian soldiers who died during the First World War by the Imperial War Graves Commission, Britain's official government body overseeing all imperial commemoration efforts. For the soldiers of the Indian Army their war experience was split between the Western Front in Europe and Mesopotamia in modern-day Iraq. They were also far more ethnically, religiously, and lingually diverse than their British and Dominion counterparts. In order to examine how geography, religion, and the imperial relationship affected Britain's commemoration of India's war dead, this study uses the Commission's own records to recreate how the IWGC created …