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2018

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Articles 18571 - 18600 of 24149

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The P53 Tumor Suppressor In The Control Of Metabolism And Ferroptosis, Keerthana Gnanapradeepan, Subhasree Basu, Thibaut Barnoud, Anna Budina-Kolomets, Che-Pei Kung, Maureen E. Murphy Jan 2018

The P53 Tumor Suppressor In The Control Of Metabolism And Ferroptosis, Keerthana Gnanapradeepan, Subhasree Basu, Thibaut Barnoud, Anna Budina-Kolomets, Che-Pei Kung, Maureen E. Murphy

Open Access Publications

No abstract provided.


Spatial Eye–Hand Coordination During Bimanual Reaching Is Not Systematically Coded In Either Lip Or Prr, Eric Mooshagian, Lawrence H. Snyder Jan 2018

Spatial Eye–Hand Coordination During Bimanual Reaching Is Not Systematically Coded In Either Lip Or Prr, Eric Mooshagian, Lawrence H. Snyder

Open Access Publications

No abstract provided.


Natural Killer Cell Recruitment To The Lung During Influenza A Virus Infection Is Dependent On Cxcr3, Ccr5, And Virus Exposure Dose, Lindsey E. Carlin, Emily A. Hemann, Zeb R. Zacharias, Jonathan W. Heusel, Kevin L. Legge Jan 2018

Natural Killer Cell Recruitment To The Lung During Influenza A Virus Infection Is Dependent On Cxcr3, Ccr5, And Virus Exposure Dose, Lindsey E. Carlin, Emily A. Hemann, Zeb R. Zacharias, Jonathan W. Heusel, Kevin L. Legge

Open Access Publications

No abstract provided.


Quantitative Assessment Of Prefrontal Cortex In Humans Relative To Nonhuman Primates, Chad J. Donahue, Matthew F. Glasser, Todd M. Preuss, James K. Rilling, David C. Van Essen Jan 2018

Quantitative Assessment Of Prefrontal Cortex In Humans Relative To Nonhuman Primates, Chad J. Donahue, Matthew F. Glasser, Todd M. Preuss, James K. Rilling, David C. Van Essen

Open Access Publications

No abstract provided.


Diversity Of Immunoglobulin Light Chain Genes In Non-Teleost Ray-Finned Fish Uncovers Igl Subdivision Into Five Ancient Isotypes, Sergey V. Guselnikov, Konstantin O. Baranov, Alexander M. Najakshin, Ludmila V. Mechetina, Nikolai A. Chikaev, Alexey I. Makunin, Sergey V. Kulemzin, Daria A. Andreyushkova, Matthias Stöck, Sven Wuertz, Jörn Gessner, Wesley C. Warren, Manfred Schartl, Vladimir A. Trifonov, Alexander V. Taranin Jan 2018

Diversity Of Immunoglobulin Light Chain Genes In Non-Teleost Ray-Finned Fish Uncovers Igl Subdivision Into Five Ancient Isotypes, Sergey V. Guselnikov, Konstantin O. Baranov, Alexander M. Najakshin, Ludmila V. Mechetina, Nikolai A. Chikaev, Alexey I. Makunin, Sergey V. Kulemzin, Daria A. Andreyushkova, Matthias Stöck, Sven Wuertz, Jörn Gessner, Wesley C. Warren, Manfred Schartl, Vladimir A. Trifonov, Alexander V. Taranin

Open Access Publications

No abstract provided.


Estrogens Promote Misfolded Proinsulin Degradation To Protect Insulin Production And Delay Diabetes, Beibei Xu, Camille Allard, Ana I. Alvarez-Mercado, Taylor Fuselier, Jun Ho Kim, Laurel A. Coons, Sylvia C. Hewitt, Fumihiko Urano, Kenneth S. Korach, Ellis R. Levin, Peter Arvan, Z. Elizabeth Floyd, Franck Mauvais-Jarvis Jan 2018

Estrogens Promote Misfolded Proinsulin Degradation To Protect Insulin Production And Delay Diabetes, Beibei Xu, Camille Allard, Ana I. Alvarez-Mercado, Taylor Fuselier, Jun Ho Kim, Laurel A. Coons, Sylvia C. Hewitt, Fumihiko Urano, Kenneth S. Korach, Ellis R. Levin, Peter Arvan, Z. Elizabeth Floyd, Franck Mauvais-Jarvis

Open Access Publications

No abstract provided.


Deficits In Burrowing Behaviors Are Associated With Mouse Models Of Neuropathic But Not Inflammatory Pain Or Migraine, Andrew J. Shepherd, Megan E. Cloud, Yu-Qing Cao, Durga P. Mohapatra Jan 2018

Deficits In Burrowing Behaviors Are Associated With Mouse Models Of Neuropathic But Not Inflammatory Pain Or Migraine, Andrew J. Shepherd, Megan E. Cloud, Yu-Qing Cao, Durga P. Mohapatra

Open Access Publications

No abstract provided.


Protocol For A Randomised Trial Of Higher Versus Lower Intensity Patient–Provider Communication Interventions To Reduce Antibiotic Misuse In Two Paediatric Ambulatory Clinics In The Usa, Kathy Goggin, Andrea Bradley-Ewing, Angela L. Myers, Brian R. Lee, Emily A. Hurley, Kirsten B. Delay, Sarah Schlachter, Areli Ramphal, Kimberly Pina, David Yu, Kirsten Weltmer, Sebastian Linnemayr, Christopher C. Butler, Jason G. Newland Jan 2018

Protocol For A Randomised Trial Of Higher Versus Lower Intensity Patient–Provider Communication Interventions To Reduce Antibiotic Misuse In Two Paediatric Ambulatory Clinics In The Usa, Kathy Goggin, Andrea Bradley-Ewing, Angela L. Myers, Brian R. Lee, Emily A. Hurley, Kirsten B. Delay, Sarah Schlachter, Areli Ramphal, Kimberly Pina, David Yu, Kirsten Weltmer, Sebastian Linnemayr, Christopher C. Butler, Jason G. Newland

Open Access Publications

No abstract provided.


Paracrine Osteoprotegerin And Β-Catenin Stabilization Support Synovial Sarcomagenesis In Periosteal Cells, Jared J. Barrott, Benjamin E. Illum, Huifeng Jin, Matthew L. Hedberg, Yanliang Wang, Allie Grossmann, Malay Haldar, Mario R. Capecchi, Kevin B. Jones Jan 2018

Paracrine Osteoprotegerin And Β-Catenin Stabilization Support Synovial Sarcomagenesis In Periosteal Cells, Jared J. Barrott, Benjamin E. Illum, Huifeng Jin, Matthew L. Hedberg, Yanliang Wang, Allie Grossmann, Malay Haldar, Mario R. Capecchi, Kevin B. Jones

Open Access Publications

No abstract provided.


Anti-Trop2 Blockade Enhances The Therapeutic Efficacy Of Erbb3 Inhibition In Head And Neck Squamous Cell Carcinoma, Nathan Redlich, Anthony M. Robinson, Kwangok P. Nickel, Andrew P. Stein, Deric L. Wheeler, Douglas R. Adkins, Ravindra Uppaluri, Randall J. Kimple, Brian A. Van Tine, Loren S. Michel Jan 2018

Anti-Trop2 Blockade Enhances The Therapeutic Efficacy Of Erbb3 Inhibition In Head And Neck Squamous Cell Carcinoma, Nathan Redlich, Anthony M. Robinson, Kwangok P. Nickel, Andrew P. Stein, Deric L. Wheeler, Douglas R. Adkins, Ravindra Uppaluri, Randall J. Kimple, Brian A. Van Tine, Loren S. Michel

Open Access Publications

No abstract provided.


A Connectomic Approach To The Lateral Geniculate Nucleus, Josh L. Morgan Jan 2018

A Connectomic Approach To The Lateral Geniculate Nucleus, Josh L. Morgan

Open Access Publications

No abstract provided.


Protocol For A Multicentre, Prospective Cohort Study Of Practice Patterns And Clinical Outcomes Associated With Emergency Department Sedation For Mechanically Ventilated Patients: The Ed-Sed Study, Brian M. Fuller, Nicholas M. Mohr, Brian W. Roberts, Christopher R. Carpenter, Marin H. Kollef, Michael S. Avidan Jan 2018

Protocol For A Multicentre, Prospective Cohort Study Of Practice Patterns And Clinical Outcomes Associated With Emergency Department Sedation For Mechanically Ventilated Patients: The Ed-Sed Study, Brian M. Fuller, Nicholas M. Mohr, Brian W. Roberts, Christopher R. Carpenter, Marin H. Kollef, Michael S. Avidan

Open Access Publications

No abstract provided.


Animal Models Of Zika Virus Infection During Pregnancy, Elizabeth A. Caine, Brett W. Jagger, Michael S. Diamond Jan 2018

Animal Models Of Zika Virus Infection During Pregnancy, Elizabeth A. Caine, Brett W. Jagger, Michael S. Diamond

Open Access Publications

No abstract provided.


Opioid Consumption After Knee Arthroscopy, Robert D. Wojahn, Ljiljana Bogunovic, Robert H. Brophy, Rick W. Wright, Matthew J. Matava, John R. Green, Corinne A. Zalomek, Amanda K. Haas, Wendy L. Holloway, Elizabeth A. Garofoli, Matthew V. Smith Jan 2018

Opioid Consumption After Knee Arthroscopy, Robert D. Wojahn, Ljiljana Bogunovic, Robert H. Brophy, Rick W. Wright, Matthew J. Matava, John R. Green, Corinne A. Zalomek, Amanda K. Haas, Wendy L. Holloway, Elizabeth A. Garofoli, Matthew V. Smith

Open Access Publications

No abstract provided.


Minimal Information For Studies Of Extracellular Vesicles 2018 (Misev2018): A Position Statement Of The International Society For Extracellular Vesicles And Update Of The Misev2014 Guidelines, Philip D. Stahl, Et Al Jan 2018

Minimal Information For Studies Of Extracellular Vesicles 2018 (Misev2018): A Position Statement Of The International Society For Extracellular Vesicles And Update Of The Misev2014 Guidelines, Philip D. Stahl, Et Al

Open Access Publications

No abstract provided.


Vegfr-3 Signaling Regulates Triglyceride Retention And Absorption In The Intestine, Trevor Shew, Nathan E. Wolins, Vincenza Cifarelli Jan 2018

Vegfr-3 Signaling Regulates Triglyceride Retention And Absorption In The Intestine, Trevor Shew, Nathan E. Wolins, Vincenza Cifarelli

Open Access Publications

No abstract provided.


Subclinical Infection Of Macaques And Baboons With A Baboon Simarterivirus, Connor R. Buechler, Matthew Semler, David A. Baker, Christina Newman, Joseph P. Cornish, Deborah Chavez, Bernadette Guerra, Robert Lanford, Kathy Brasky, Jens H. Kuhn, Reed F. Johnson, David H. O'Connor, Adam L. Bailey Jan 2018

Subclinical Infection Of Macaques And Baboons With A Baboon Simarterivirus, Connor R. Buechler, Matthew Semler, David A. Baker, Christina Newman, Joseph P. Cornish, Deborah Chavez, Bernadette Guerra, Robert Lanford, Kathy Brasky, Jens H. Kuhn, Reed F. Johnson, David H. O'Connor, Adam L. Bailey

Open Access Publications

No abstract provided.


Homeostatic Plasticity In Neural Development, Nai-Wen Tien, Daniel Kerschensteiner Jan 2018

Homeostatic Plasticity In Neural Development, Nai-Wen Tien, Daniel Kerschensteiner

Open Access Publications

No abstract provided.


Il23 And Tgf-Ss Diminish Macrophage Associated Metastasis In Pancreatic Carcinoma, S. Mazher Hussain, Leighton F. Reed, Bradley A. Krasnick, Gustavo Miranda-Carboni, Ryan C. Fields, Ye Bi, Abul Elahi, Abidemi Ajidahun, Paxton V. Dickson, Jeremiah L. Deneve, William G. Hawkins, David Shibata, Evan S. Glazer Jan 2018

Il23 And Tgf-Ss Diminish Macrophage Associated Metastasis In Pancreatic Carcinoma, S. Mazher Hussain, Leighton F. Reed, Bradley A. Krasnick, Gustavo Miranda-Carboni, Ryan C. Fields, Ye Bi, Abul Elahi, Abidemi Ajidahun, Paxton V. Dickson, Jeremiah L. Deneve, William G. Hawkins, David Shibata, Evan S. Glazer

Open Access Publications

No abstract provided.


Transient Pp2a Inhibition Alleviates Normal Tissue Stem Cell Susceptibility To Cell Death During Radiotherapy, Maria Rita Fabbrizi, Barbara Meyer, Sandeep Misri, Suyash Raj, Cheri L. Zobel, Dennis E. Hallahan, Girdhar G. Sharma Jan 2018

Transient Pp2a Inhibition Alleviates Normal Tissue Stem Cell Susceptibility To Cell Death During Radiotherapy, Maria Rita Fabbrizi, Barbara Meyer, Sandeep Misri, Suyash Raj, Cheri L. Zobel, Dennis E. Hallahan, Girdhar G. Sharma

Open Access Publications

No abstract provided.


Spatial And Temporal Changes In Extracellular Elastin And Laminin Distribution During Lung Alveolar Development, Yongfeng Luo, Nan Li, Hui Chen, G. Esteban Fernandez, David Warburton, Rex Moats, Robert P. Mecham, Daria Krenitsky, Gloria S. Pryhuber, Wei Shi Jan 2018

Spatial And Temporal Changes In Extracellular Elastin And Laminin Distribution During Lung Alveolar Development, Yongfeng Luo, Nan Li, Hui Chen, G. Esteban Fernandez, David Warburton, Rex Moats, Robert P. Mecham, Daria Krenitsky, Gloria S. Pryhuber, Wei Shi

Open Access Publications

No abstract provided.


Bioelectric-Calcineurin Signaling Module Regulates Allometric Growth And Size Of The Zebrafish Fin, Jacob M. Daane, Jennifer Lanni, Ina Rothenberg, Guiscard Seebohm, Charles W. Higdon, Stephen L. Johnson, Matthew P. Harris Jan 2018

Bioelectric-Calcineurin Signaling Module Regulates Allometric Growth And Size Of The Zebrafish Fin, Jacob M. Daane, Jennifer Lanni, Ina Rothenberg, Guiscard Seebohm, Charles W. Higdon, Stephen L. Johnson, Matthew P. Harris

Open Access Publications

No abstract provided.


Apoε4 Disrupts Neurovascular Regulation And Undermines White Matter Integrity And Cognitive Function, Kenzo Koizumi, Yorito Hattori, Sung Ji Ahn, Izaskun Buendia, Antonio Ciacciarelli, Ken Uekawa, Gang Wang, Abigail Hiller, Lingzhi Zhao, Henning U. Voss, Steven M. Paul, Chris Schaffer, Laibaik Park, Constantino Iadecola Jan 2018

Apoε4 Disrupts Neurovascular Regulation And Undermines White Matter Integrity And Cognitive Function, Kenzo Koizumi, Yorito Hattori, Sung Ji Ahn, Izaskun Buendia, Antonio Ciacciarelli, Ken Uekawa, Gang Wang, Abigail Hiller, Lingzhi Zhao, Henning U. Voss, Steven M. Paul, Chris Schaffer, Laibaik Park, Constantino Iadecola

Open Access Publications

No abstract provided.


Disrupted Cholesterol Metabolism Promotes Age-Related Photoreceptor Neurodegeneration, Norimitsu Ban, Tae Jun Lee, Abdoulaye Sene, Zhenyu Dong, Andrea Santeford, Jonathan B. Lin, Daniel S. Ory, Rajendra S. Apte Jan 2018

Disrupted Cholesterol Metabolism Promotes Age-Related Photoreceptor Neurodegeneration, Norimitsu Ban, Tae Jun Lee, Abdoulaye Sene, Zhenyu Dong, Andrea Santeford, Jonathan B. Lin, Daniel S. Ory, Rajendra S. Apte

Open Access Publications

No abstract provided.


Combination Anti-Aβ Treatment Maximizes Cognitive Recovery And Rebalances Mtor Signaling In App Mice, Angie C.A. Chiang, Stephanie W. Fowler, Ricky R. Savjani, Susan G. Hilsenbeck, Clare E. Wallace, John R. Cirrito, Pritam Das, Joanna L. Jankowsky Jan 2018

Combination Anti-Aβ Treatment Maximizes Cognitive Recovery And Rebalances Mtor Signaling In App Mice, Angie C.A. Chiang, Stephanie W. Fowler, Ricky R. Savjani, Susan G. Hilsenbeck, Clare E. Wallace, John R. Cirrito, Pritam Das, Joanna L. Jankowsky

Open Access Publications

Drug development for Alzheimer's disease has endeavored to lower amyloid β (Aβ) by either blocking production or promoting clearance. The benefit of combining these approaches has been examined in mouse models and shown to improve pathological measures of disease over single treatment; however, the impact on cellular and cognitive functions affected by Aβ has not been tested. We used a controllable APP transgenic mouse model to test whether combining genetic suppression of Aβ production with passive anti-Aβ immunization improved functional outcomes over either treatment alone. Compared with behavior before treatment, arresting further Aβ production (but not passive immunization) was sufficient …


Lifelong Reduction In Complex Iv Induces Tissue‐Specific Metabolic Effects But Does Not Reduce Lifespan Or Healthspan In Mice, Sathyaseelan S. Deepa, Gavin Pharaoh, Michael Kinter, Vivian Diaz, Wilson C. Fok, Kaitlyn Riddle, Daniel Pulliam, Shauna Hill, Kathleen E. Fischer, Vanessa Soto, Constantin Georgescu, Jonathan D. Wren, Carlo Viscomi, Arlan Richardson, Holly Van Remmen Jan 2018

Lifelong Reduction In Complex Iv Induces Tissue‐Specific Metabolic Effects But Does Not Reduce Lifespan Or Healthspan In Mice, Sathyaseelan S. Deepa, Gavin Pharaoh, Michael Kinter, Vivian Diaz, Wilson C. Fok, Kaitlyn Riddle, Daniel Pulliam, Shauna Hill, Kathleen E. Fischer, Vanessa Soto, Constantin Georgescu, Jonathan D. Wren, Carlo Viscomi, Arlan Richardson, Holly Van Remmen

Open Access Publications

No abstract provided.


The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss, Sumana Ghosh, Sandeep Sheth, Kelly Sheehan, Debashree Mukherjea, Asmita Dhukhwa, Vikrant Borse, Leonard P. Rybak, Vickram Ramkumar Jan 2018

The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss, Sumana Ghosh, Sandeep Sheth, Kelly Sheehan, Debashree Mukherjea, Asmita Dhukhwa, Vikrant Borse, Leonard P. Rybak, Vickram Ramkumar

Open Access Publications

No abstract provided.


C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis By Affecting Heptadecenoic Acid Production, Yuanbao Li, Chunxia Wang, Yikai Huang, Rong Fu, Hanxi Zheng, Yi Zhu, Xiaoruo Shi, Prashanth K. Padakanti, Zhude Tu, Xiong Su, Huimin Zhang Jan 2018

C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis By Affecting Heptadecenoic Acid Production, Yuanbao Li, Chunxia Wang, Yikai Huang, Rong Fu, Hanxi Zheng, Yi Zhu, Xiaoruo Shi, Prashanth K. Padakanti, Zhude Tu, Xiong Su, Huimin Zhang

Open Access Publications

No abstract provided.


Antithrombin Perfluorocarbon Nanoparticles Improve Renal Allograft Function In A Murine Deceased Criteria Donor Model, Chandu Vemuri, Gundumi A. Upadhya, Batool Arif, Jianluo Jia, Yiing Lin, Joseph P. Gaut, Jawad Fazal, Hua Pan, Samuel A. Wickline, William C. Chapman Jan 2018

Antithrombin Perfluorocarbon Nanoparticles Improve Renal Allograft Function In A Murine Deceased Criteria Donor Model, Chandu Vemuri, Gundumi A. Upadhya, Batool Arif, Jianluo Jia, Yiing Lin, Joseph P. Gaut, Jawad Fazal, Hua Pan, Samuel A. Wickline, William C. Chapman

Open Access Publications

No abstract provided.


The Professionalism And Integrity In Research Program: Description And Preliminary Outcomes, James M. Dubois, John T. Chibnall, Raymond Tait, Jillon S. Vander Wal Jan 2018

The Professionalism And Integrity In Research Program: Description And Preliminary Outcomes, James M. Dubois, John T. Chibnall, Raymond Tait, Jillon S. Vander Wal

Open Access Publications

No abstract provided.