Digital Commons Network^™

The Relationship Between Marbling, Superoxide Dismutase, And Beef Tenderness, Nicolas J. Herrera, Emery K. Wilkerson, Katherine I. Domenech-Perez Perez, Felipe A. Ribeiro, Michael D. Chao, Chris Calkins

Nebraska Beef Cattle Reports

This study was conducted to evaluate the relationships between animal oxidative status (as indicated by superoxide dismutase [SOD] activity) to marbling and beef tenderness. Prime and Select-grade strip loins were selected and aged for 2, 7, 14, 21, and 28 days for Warner Bratzler shear force, Troponin-T, and SOD activity. Results showed that meat exhibiting higher levels of marbling had lower shear force values and thus were more tender. Low-marbled samples tended to have a greater tenderness response to aging. The effect of oxidative stress, however, was not evident in this study as SOD values were similar. Although the effects …

Evaluation Of Corn Distillers Solubles On Finishing Steer Performance, Benjamin H. Hansen, Curtis J. Bittner, Bradley M. Boyd Boyd, F. Henry Hilscher, Jim C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

A finishing study was conducted to evaluate the effects of feeding 0, 8, 16, or 20% corn distillers solubles (CDS), as well as the effects of feeding a combination of 16% CDS and 20% wet distillers grains plus solubles (WDGS) to replace a blend of dry-rolled and high-moisture corn on finishing steer performance. As inclusions of CDS increased, ADG linearly increased and F:G linearly decreased. Feeding value of CDS at 20% inclusion was determined to be 147% compared to the corn blend. The addition of WDGS resulted in a decrease in DMI with similar ADG, resulting in a decrease in …

Effect Of Myoglobin State On Color Stability Of High Pressure Processed Ground Beef, Jhinuk Gupta, Chad G. Bower, George A. Cavender Cavender, Gary A. Sullivan

Nebraska Beef Cattle Reports

High pressure processing, a non-thermal pasteurization technique, can reduce E. coli in beef but the use is limited due to discoloration of raw beef after high pressure processing. Different states of myoglobin have inherently different color stability. The objective of this study was to determine the impact of myoglobin state on color stability of raw beef patties treated with high pressure processing. Modified atmosphere packaging (high oxygen-oxymyoglobin, carbon monoxide-carboxymyoglobin), vacuum packaging (deoxymyoglobin) or added potassium ferricyanide (metmyoglobin) treatments were used to prepare patties with desired myoglobin states. Color was measured (CIE L*, a*, b*) before and after high pressure processing …

Effect Of Ingredients And Packaging On Color Of High Pressure Processed Ground Beef, Jhinuk Gupta, Chad G. Bower, George A. Cavender Cavender, Gary A. Sullivan

Nebraska Beef Cattle Reports

High pressure processing is a non-thermal pasteurization technique to control pathogens, like E. coli. However, color changes in raw beef induced by processing restrict high pressure processing’s use within the beef industry. The objectives of this study were to investigate the effects of adding curing agents (nitrite) and packaging with or without reducing compounds (ascorbic acid/erythorbate) on color retention in high pressure processed ground beef. High pressure processing resulted in a detrimental effect on the color of the beef patties for all treatments. Lightness and yellowness increased and redness decreased after high pressure processing. The effect remained the same throughout …

Effects Of Production System On Cow And Calf Performance, Shelby E. Gardine, Jason M. Warner, Robert G. Bondurant Bondurant, F. Henry Hilscher, Karla H. Jenkins, Galen E. Erickson, Terry J. Klopfenstein

Nebraska Beef Cattle Reports

Limited traditional forage resources have prompted interest for alternative cow-calf production systems. This study evaluated the effects of two winter cow-calf production systems (cornstalk grazing and dry-lot feeding) on cow-calf performance in a summer-calving, intensively managed cowherd at two locations. Grazing cow-calf pairs on cornstalks resulted in similar or lower ending BW of cows and lower ADG of calves when compared to cow-calf pairs wintered in the dry-lot. A partial budget of incorporating winter cornstalk grazing into an intensive production system suggests that cows wintered on cornstalks may be $137 more profitable compared to cows wintered in the dry-lot.

Effects Of Production System And Post-Weaning Management On Finishing Performance And Carcass Characteristics Of Steer And Heifer Calves, Shelby E. Gardine, Bradley M. Boyd, Curtis J. Bittner Bittner, F. Henry Hilscher, Karla H. Jenkins, Galen E. Erickson, Terry J. Klopfenstein

Nebraska Beef Cattle Reports

This study evaluated the effects of cow-calf production system and post-weaning management on finishing performance and carcass characteristics of steer and heifer calves. Calves that were wintered on cornstalks prior to weaning had lighter initial BW compared to calves that were wintered in the dry-lot; however, final BW and carcass weight were similar between treatments. Post-weaning management was either adapting calves to a finishing diet following weaning or feeding a grower diet prior to the finishing phase. When harvested at similar back fat, calves that were fed a grower diet for 76 days prior to the finishing phase had 71 …

Evaluation Of Protein From Distillers Grains In Finishing Diets On Nutrient Digestibility, Zachary E. Carlson, Jana L. Gramkow, Hannah C. Wilson Wilson, Melissa L. Jolly-Breithaupt, Galen E. Erickson, Jim C. Macdonald, Matt K. Luebbe

Nebraska Beef Cattle Reports

A metabolism trial was conducted to evaluate protein from modified distillers grains plus solubles (MDGS) in finishing diets on nutrient digestibility and ruminal fermentation characteristics. Isolated protein from corn was not different than MDGS for dry matter, organic matter, or neutral detergent fiber digestibility. However, steers fed MDGS tended to have lower total tract organic matter digestibility compared to corn and protein from corn. Protein had greater total tract organic matter and starch digestibility than MDGS. Protein from corn did not contribute towards the lower digestibility of MDGS. Protein is more easily digestible than the other components in distillers grains …

Production Of High-Quality Beef–The Nebraska Advantage, Chris R. Calkins

Nebraska Beef Cattle Reports

Here is a clear description of the Nebraska Advantage in producing high-quality beef: the right genetics, numerous pastures, a multitude of cattle, great water resources, locally-grown corn, the availability of ethanol byproducts for feed, and young cattle that grow fast, with sufficient marbling and subcutaneous fat to ensure tender, flavorful, beef. The science of beef quality supports this production system. The state supports its citizens and agriculture through the University of Nebraska and the Nebraska Department of Agriculture, augmenting the infrastructure. If one could invent an ideal place to produce high-quality beef, it would look much like Nebraska! The impact …

Potential Variation In Determination Of Longissimus Muscle Area In Carcasses From Heifers Fed With Or Without Zilpaterol Hydrochloride, Chris R. Calkins, Jenna J. O'Daniel, Govindarajan Konda Naganathan Naganathan, Kellen B. Hart, Katherine I. Domenech-Perez, T.B. Schmidt

Nebraska Beef Cattle Reports

This study was conducted to evaluate some sources of potential variation in determination of longissimus muscle area between the 12th and 13th ribs of carcasses from heifers fed with or without zilpaterol hydochloride. Cross sections of the rib-loin were taken cranial to the 11th rib and caudal to the 13th rib, about 3–4 millimeters thick at 90 degrees perpendicular to the long axis of the longissimus muscle. Potential variation of longissimus muscle area can arise from the natural variation of muscle size when cutting between the 12th and 13th ribs (up to 9%). Deviation in cutting perpendicular to the long …

Impact Of Feeding Distillers Grains With Or Without Oil Removal As Well As Supplemental Corn Oil On Nutrient Digestibility By Finishing Cattle, Jordan E. Burhoop, Melissa L. Jolly-Breithaupt, Jana L. Gramkow Gramkow, Matthew K. Luebbe, Jim C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

A digestion trial was conducted to determine the effects of the removal of corn oil from modified distillers grains plus solubles (MDGS) and the impact of supplemental corn oil on finishing cattle nutrient digestion. Four treatments were evaluated: a corn control diet (CON), 40% de-oiled MDGS (DO MDGS), or 38% de-oiled MDGS plus 2% corn oil (MDGS + Oil) formulated to equal the fat content of FF MDGS, or 40% full fat MDGS (FF MDGS). Treatment differences were observed for digestibility of dry matter, organic matter, and fiber, but not for fat. When oil was added to de-oiled MDGS, digestibility …

Effects Of Late Gestation Supplementation, Synchronization, And Creep Feeding In A Spring Calving Beef Herd In The Nebraska Sandhills, Devin Broadhead, L. A. Stalker, Jacki A. Musgrave Musgrave, Richard N. Funston

Nebraska Beef Cattle Reports

Supplementation during winter grazing increased cow BW and BCS but had no effect on reproduction or calf performance, thus increasing production costs without increasing returns. Using a CIDR for estrus synchronization in a herd with existing acceptable reproductive performance did not increase cow pregnancy rate or advance calving date. Feeding creep feed to calves is an effective means of increasing weaning BW which resulted in increased live and carcass weight. Under the conditions of this study, when additional feed and price slide for heavier calves was considered, feeding creep feed did not result in added profits.

Field Evaluations Of Insecticide Modes Of Action Classes For Control Of Horn Flies In Nebraska, David J. Boxler, Gary J. Brewer, Richard N. Funston Funston, Jacqueline A. Musgrave

Nebraska Beef Cattle Reports

Insecticides of different Mode of Action (MoA) classes were tested for their ability to reduce horn fly populations on cattle in Nebraska pastures between 2009 and 2016. Macrocyclic lactone products were the most efficacious, reducing horn fly numbers by an average of 93% over ten location years of testing. Organophosphate and pyrethroid MoA products, tested in 7 and 12 location years, reduced fly numbers by 75% and 73%. Classes tested only once were METI (88% reduction) and a combination of organophosphate + pyrethroid (64%).

Evaluation Of Revalor-Xh For Beef Heifers Fed Different Days On Feed, Robert G. Bondurant, Marshall N. Streeter, Galen E. Erickson Erickson, James C. Macdonald, Matt K. Luebbe

Nebraska Beef Cattle Reports

Heifers were treated with either no implant, an initial implant of Revalor-200 and re-implanted with Revalor-200, or Revalor-XH and assigned to one of four serial slaughter harvests at 151, 165, 179, and 193 days on feed to determine the effects on feedlot performance and carcass characteristics. Implanting heifers increased final BW, ADG and HCW while decreasing marbling score and improving feed efficiency compared to non-implanted heifers. Increasing days on feed decreased ADG while increasing feed efficiency, HCW, fat thickness, marbling score, and calculated yield grade. By increasing HCW sold, implanting revenue can be maximized, assuming added risk for YG discounts.

Effect Of Supplementation During The Breeding Season On A May-Calving Herd In The Nebraska Sandhills, Alicia C. Lansford, Jacki A. Musgrave, Richard N. Funston Funston

Nebraska Beef Cattle Reports

Females in their first and second breeding season received either a 32% crude protein (DM) supplement or no supplement throughout the breeding season. Supplementation did not affect heifer BW, BCS, and pregnancy rate at pregnancy diagnosis. Supplementation impacted primiparous cow BW and BCS at pregnancy diagnosis, but did not affect pregnancy rates. Calf birth weight and dystocia rates were unaffected by supplementation for both heifers and primiparous cow. Calves nursing supplemented dams were heavier at weaning. Greater supplementation may be needed to affect pregnancy rate.

Itihas Vol. 18 Issue No. 1, Sastra Univ

ITIHAS

NEWSLETTER FROM SASTRA DEEMED UNIVERSITY

Death In Life And Life In Death: Forms And Fates Of The Human, Connor Graham, Alfred Montoya

Sociology & Anthropology Faculty Research

This chapter traces the origins, meanings and characteristics of “the human” in recent time – its forms. The chapter contends that, instead of being immutable, “the human” has taken different forms, been ascribed different meanings, and exhibited different characteristics over time. Our approach to “the human” contributes to this volume on digital existence, which confronts existential questions centered on being and technology, with historical and anthropological awareness. We aim to show, through Foucault’s (1971 ) insistence upon the forms of subjectivity as opposed to its substance, how understandings of “the human” are subject to change and transformation. Exploring these diverse …

Peptide Density Targets And Impedes Triple Negative Breast Cancer Metastasis, Daxing Liu, Peng Guo, Craig Mccarthy, Biran Wang, Yu Tao, Debra Auguste

Publications and Research

The C-X-C chemokine receptor type 4 (CXCR4, CD184) pathway is a key regulator of cancer metastasis. Existing therapeutics that block CXCR4 signaling are dependent on single molecule-receptor interactions or silencing CXCR4 expression. CXCR4 localizes in lipid rafts and forms dimers therefore CXCR4 targeting and signaling may depend on ligand density. Herein, we report liposomes presenting a CXCR4 binding peptide (DV1) as a threedimensional molecular array, ranging from 9k to 74k molecules μm−2, target triple negative breast cancer (TNBC). TNBC cells exhibit a maxima in binding and uptake of DV1functionalized liposomes (L-DV1) in vitro at a specific density, which yields a …

Continuous Monitoring Devices And Seizure Patterns By Glucose, Time And Lateralized Seizure Onset., Katie M Kinnear, Nicole M Warner, Alan M Haltiner, Michael J Doherty

Articles, Abstracts, and Reports

Objectives: To investigate if glucose levels influence seizure patterns.

Materials and methods: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.

Results: Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).

Conclusion: Seizure onset laterality and spread vary with glucose and time …

"Of Mice And Measures": A Project To Improve How We Advance Duchenne Muscular Dystrophy Therapies To The Clinic., Heather Gordish-Dressman, Raffaella Willmann, Laura Dalle Pazze, Arati Kreibich, Maaike Van Putten, Ahlke Heydemann, Laurent P. Bogdanik, Cathleen Lutz, Kay Davies, Alexis R Demonbruen, Dongsheng Duan, David Elsey, So-Ichiro Fukada, Mahasweta Girgenrath, J Patrick Gonzalez, Miranda D Grounds, Andy Nichols, Terry Partridge, Marco Passini, Francesca Sanarica, Frederick J Schnell, Dominic J Wells, Toshifumi Yokota, Courtney S Young, Zhong Zhong, Christopher Spurney, Melissa Spencer, Annamaria De Luca, Kanneboyina Nagaraju, Annemieke Aartsma-Rus

Faculty Research 2018

A new line of dystrophic mdx mice on the DBA/2J (D2) background has emerged as a candidate to study the efficacy of therapeutic approaches for Duchenne muscular dystrophy (DMD). These mice harbor genetic polymorphisms that appear to increase the severity of the dystropathology, with disease modifiers that also occur in DMD patients, making them attractive for efficacy studies and drug development. This workshop aimed at collecting and consolidating available data on the pathological features and the natural history of these new D2/mdx mice, for comparison with classic mdx mice and controls, and to identify gaps in information and their potential …

Comparative Transcriptomic Analysis Of Human Placentae At Term And Preterm Delivery., Alison G Paquette, Heather M Brockway, Nathan D Price, Louis J Muglia

Articles, Abstracts, and Reports

Preterm birth affects 1 out of every 10 infants in the United States, resulting in substantial neonatal morbidity and mortality. Currently, there are few predictive markers and few treatment options to prevent preterm birth. A healthy, functioning placenta is essential to positive pregnancy outcomes. Previous studies have suggested that placental pathology may play a role in preterm birth etiology. Therefore, we tested the hypothesis that preterm placentae may exhibit unique transcriptomic signatures compared to term samples reflective of their abnormal biology leading to this adverse outcome. We aggregated publicly available placental villous microarray data to generate a preterm and term …

Effect Of X-Word Grammar And Traditional Grammar Instruction On Grammatical Accuracy, Sue Livingston, Andi Toce, Cyndi Casey, Fernando Montoya, Bonny R. Hart, Carmela O'Flaherty

Publications and Research

This study first briefly describes an instructional approach to teaching grammar known as X-Word Grammar and then compares its effectiveness in assisting students in achieving grammatical accuracy with traditionally taught grammar. Two groups of L2 pre-college students were taught using curricula and practice procedures in two different grammar texts over a three-month period of time for 20% of their class time. Essays written at three different times were analyzed for the correct and incorrect use of sentence patterns and verb constructs. Results demonstrated that improvement (writing with less error) was larger in both categories for the X-Word Grammar group and …

Simultaneous Use Of Physiological Sensors For A Neuromarketing Task, Charles Descheneaux

Electronic Theses and Dissertations

Physiological measurements have become more popular in Psychological research over the past ten years. These advancements allowed different objective sensors to become another measurement tool in a scientific arsenal of collecting data. Traditionally, performance and after task subjective measures have been used for most studies in Psychological research. With the opportunity to use these subjective measures along with objective measures, more data can be collected during research and therefore potentially produce better quality conclusions. Eye Tracking (ET), functional near infrared (fNIR), transcranial Doppler ultrasound (TCD), electrocardiogram (EKG) and the electroencephalogram (EEG) have shown great promise in their ability to produce …

Simulating Human Pleura Performance In Medical Training Using Measured Tissue Mechanical Properties, Jack Norfleet

Electronic Theses and Dissertations

Medical simulations provide hands-on training at various levels of medical expertise. Yet these simulators fail to accurately mimic the look, feel and behavior of human tissue. Applying measured mechanical properties from human cadaver tissues promises to improve the fidelity of simulated tissue behaviors when subjected to medical procedures. Samples of human parietal pleura were tested under uniaxial tension to failure and measured characteristics were replicated in synthetic pleura. Context specific parameters were then collected and compared between human pleura and the new synthetics. These comparisons tested the hypothesis; H1 Gaps exist between synthetic and human pleura performance, H2: Human tissue …

Development Of Soil Compressibility Prediction Models, Scott Kirts

Electronic Theses and Dissertations

The magnitude of the overall settlement depends on several variables such as the Compression Index, Cc, and Recompression Index, Cr, which are determined by a consolidation test; however, the test is time consuming and labor intensive. Correlations have been developed to approximate these compressibility indexes. In this study, a data driven approach has been employed in order to estimate Cc and Cr. Support Vector Machines classification is used to determine the number of distinct models to be developed. The statistical models are built through a forward selection stepwise regression procedure. Ten variables were used, including the moisture content (w), initial …

Contrasting Portrayals Of Children In 1 Samuel, A. James Murphy

School of American and Global Studies Faculty Publications with a Focus on History, Philosophy, Political Science, and Religion

Scholars have developed a number of interpretive methods and approaches to the Bible over the last century. Perhaps the first new approach of the twenty-first century is child-centered, or childist interpretation. Child-centered critical readings are largely an outgrowth of feminist interpretation, which has illuminated biblical figures like Sarah, Esther, and Paul’s writings on women in new ways for decades now. Unlike female interpreters, however, every one of us has been a child! Yet similarly, those of us who use this approach typically do so in conjunction with other lenses (e.g., archaeological, historical, literary, or rhetorical) with which to read the …

Maritime Spatial Planning Supported By Infrastructure For Spatial Information In Europe (Inspire), Andrej Abramic, Emanuele Bigagli, Vittorio Barale, Alberto Lorenzo-Alonso, Conor Norton

Articles

The implementation of Directive 2007/2/EC - INSPIRE can improve and actually strengthen the informationmanagement and data infrastructures needed for setting up Maritime Spatial Planning (MSP) processes. Evidencefor this comes from three parallel analyses: links between the MSP Framework Directive and INSPIRE compo-nents and implementation; the availability of marine and maritime data through the INSPIRE Geo-Portal; andthe adequacy of using an INSPIRE data model for mapping maritime spatial plans. Thefirst item identifiesINSPIRE as a relevant instrument not only for data collection, but additionally for increasing transparency of theMSP processes, using already operational national and European data infrastructure. The marine/maritime dataavailability analysis …

Absolute Oral Bioavailability Of Creatine Monohydrate In Rats: Debunking A Myth, Eman A. Alraddadi, Ryan Lillico, Jonathan L. Vennerstrom, Ted M. Lakowski, Donald W. Miller

Journal Articles: Pharmaceutical Sciences

Creatine is an ergogenic compound used by athletes to enhance performance. Supplementation with creatine monohydrate (CM) has been suggested for musculoskeletal and neurological disorders. Until now, little is known about its pharmacokinetic profile. Our objective was to determine the oral bioavailability of CM and the influence of dose on oral absorption. Rats were dosed orally with low dose (10 mg/kg) or high dose (70 mg/kg)

Flupirtine Derivatives As Potential Treatment For The Neuronal Ceroid Lipofuscinoses, Joelle Makoukji, Fadi Saadeh, Karl Albert Mansour, Sally El-Sitt, Jamal Al Ali, Nihar Kinarivala, Paul C. Trippier, Rose-Mary Boustany

Journal Articles: Pharmaceutical Sciences

OBJECTIVE: Neuronal Ceroid Lipofuscinoses (NCL) are fatal inherited neurodegenerative diseases with established neuronal cell death and increased ceramide levels in brain, hence, a need for disease-modifying drug candidates, with potential to enhance growth, reduce apoptosis and lower ceramide in neuronal precursor PC12 cells and human NCL cell lines using enhanced flupirtine aromatic carbamate derivatives in vitro.

METHODS: Aromatic carbamate derivatives were tested by establishing growth curves under pro-apoptotic conditions and activity evaluated by trypan blue and JC-1 staining, as well as a drop in pro-apoptotic ceramide in neuronal precursor PC12 cells following siRNA knockdown of the

RESULTS: Retigabine, the benzyl-derivatized …

Exclusion In Digital Markets, Konstantinos Stylianou

Michigan Telecommunications & Technology Law Review

This article recasts the existing analytical framework on exclusion to account for the technology-intensive nature of digital markets. It discusses:

a) technological ways that affect the competitive intensity in digital markets
b) empirical data on the durability of competitive advantage in digital markets, and
c) the nature of exclusion as a monopolization tactic from a technological point of view

The technology element is important because as a matter of order it is technological capabilities and limitations that define what the transactional overlay can be, not the other way around. Economists start from the pre-assumption that “in the beginning there [are] …

Arbiters Of Decency: A Study Of Legislators' Eighth Amendment Role, Aliza Plener Cover

Articles

Within Eighth Amendment doctrine, legislators are arbiters of contemporary values. The United States Supreme Court looks closely to state and federal death penalty legislation to determine whether a given punishment is out of keeping with “evolving standards of decency.” Those who draft, debate, and vote on death penalty laws thus participate in both ordinary and higher lawmaking. This Article investigates this dual role.

We coded and aggregated information about every floor statement made in the legislative debates preceding the recent passage of bills abolishing the death penalty in Connecticut, Illinois, and Nebraska. We categorized all statements according to their position …