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Full-Text Articles in Entire DC Network
Exploring The Knowledge Of Algebra For Teaching., Jonathan David Watkins
Exploring The Knowledge Of Algebra For Teaching., Jonathan David Watkins
Electronic Theses and Dissertations
For the past few decades, researchers in mathematics education have been exploring the concept of pedagogical content knowledge (PCK)—or knowledge related to teaching content—and applying it to various areas of mathematics, such as algebra. Research related to teacher knowledge of algebra is critical because researchers (e.g., Hill, Rowan, & Ball, 2005) have found correlations between some types of teacher knowledge and student achievement in mathematics; students from around the world are outperforming U.S. students on international assessments of mathematics, including algebra (Organization for Economic Cooperation and Development, 2014, 2016); and algebra plays an integral role in the K-12 mathematics curriculum …
Conquerors Or Cowards: The Role Of The Kentucky Mounted Militia In The Indian Wars From 1768 To 1841., Joel Anderson
Conquerors Or Cowards: The Role Of The Kentucky Mounted Militia In The Indian Wars From 1768 To 1841., Joel Anderson
Electronic Theses and Dissertations
The thesis argues that Kentuckians developed the myth that the Kentucky Mounted Volunteers were the most effective troops to fight Native American warriors in the Northwest Indian War of 1790 to 1794 and the War of 1812. The idea that these troops were the best fighters originated in the decades following the War of 1812 as Kentuckians generated a communal history. Residents of the state listened to orators mythologize the successes of mounted Kentuckians in battle, while remembering the foot militia for their sacrifices rather than their shortcomings.
Influences Of Porphyromonas Gingivalis On The Viability Of Esophageal Cancer Cells., Muddasir Mohammed
Influences Of Porphyromonas Gingivalis On The Viability Of Esophageal Cancer Cells., Muddasir Mohammed
Electronic Theses and Dissertations
A recent study demonstrated an association between the Porphyromonas gingivalis (Pg)infection and the progression of ESCC (Gao et al., 2016). However, how Pg infection affects the nature of ESCC remains unknown. We examined the effects of Pg on the proliferation and chemotherapy drug-induced apoptosis of ESCC cells and elucidated the signaling molecules involved in these processes. Method: Apoptosis and cell proliferation were tested using Flow cytometry and Tetrazolium salt based proliferation assays respectively. Western Blot was utilized to detect the protein expression. CDK2 and Cyclin E were knocked down in the ESCC cells through transfection. Unpaired T-test and …
North American Indigenous Collection And Curation And Its Impact On Market Arts., Adelaide Mccomb
North American Indigenous Collection And Curation And Its Impact On Market Arts., Adelaide Mccomb
Electronic Theses and Dissertations
This thesis examines the history of two North American Indigenous groups, those belonging to the Great Plains and the Arctic, and observes how settler-colonial influence determined the collection and curation of arts and artifacts in these areas. This art includes a mention of pre-Colombian works, but focuses predominantly on works being made after “first-contact” through the contemporary ear. The paper addresses the effect imperialist history has had on the development of Indigenous art markets, and how institutions such as museums may address them through ethical practices, and efforts to decolonize museum spaces.
Counter Narratives: A Phenomenological Study Of High Achieving African American Male High School Students., De'nay Lanise Speaks
Counter Narratives: A Phenomenological Study Of High Achieving African American Male High School Students., De'nay Lanise Speaks
Electronic Theses and Dissertations
This dissertation examined the contributing factors to the success of high achieving African American male high school students who attend an all-male, predominantly Black, college-preparatory academy. The study took place in an urban, Midwestern school district and highlighted the lived experience and perspectives of students who have at least a 3.0 grade point average. Through the lens of Critical Race Theory, this study was an effort to bring attention to counter narratives to the otherwise deleterious image portrayed of African American males. The history and plight of the African American male is included to provide a comprehensive understanding of the …
Japanese-English Translation: "Absolute-Contradictory Self-Identity"--Nishida Kitarō, Translated By Christopher Southward, Christopher Southward
Japanese-English Translation: "Absolute-Contradictory Self-Identity"--Nishida Kitarō, Translated By Christopher Southward, Christopher Southward
Comparative Literature Faculty and Student Scholarship
Complete draft translation of Nishida Kitarō’s “Absolute-contradictory Self-identity” (First published in Thought, No. 202, March, 1939, Iwanami Shoten, Tokyo, Japan) [「絶対矛盾的自己同一」、千九百三十九年三月初発、『思想』、岩波書店、東京]. Introduction, conceptual apparatus/glossary, substantive line edits, corrections, revisions, and notes underway. Please contact translator before citing. All rights reserved, Christopher Southward (2018). Source, Aozora Bunko (a digital archive of Japanese-language works in the public domain): Current text: https://www.aozora.gr.jp/cards/000182/files/1755_53374.html; General: https://www.aozora.gr.jp/
Insights Into The Reactivation, Regulation And Essentiality Of Oxidative Protein Folding Pathways In Actinobacteria, Belkys Sanchez
Insights Into The Reactivation, Regulation And Essentiality Of Oxidative Protein Folding Pathways In Actinobacteria, Belkys Sanchez
Dissertations and Theses (Open Access)
Accurate disulfide bond formation is important for proper folding, stability and function of exported proteins. The process of disulfide bond formation, termed oxidative protein folding, is catalyzed by thiol-disulfide oxidoreductase enzymes. Oxidative protein folding pathways influence processes essential for bacterial physiology and pathogenicity. In the Gram-positive actinobacterial pathogens Actinomyces oris and Corynebacterium diphtheriae oxidative protein folding is catalyzed by the primary thiol-disulfide oxidoreductase MdbA. MdbA is required for assembly of adhesive pilus, which mediate receptor-dependent bacterial interactions, or coaggregation, in A. oris. In the first part of this dissertation, I identify components of the electron transport chain (ETC) required for …
Grazing Strategy Effects On Utilization, Animal Performance, Aboveground Production, Species Composition, And Soil Properties On Nebraska Sandhills Meadow, Aaron Shropshire
Grazing Strategy Effects On Utilization, Animal Performance, Aboveground Production, Species Composition, And Soil Properties On Nebraska Sandhills Meadow, Aaron Shropshire
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
Ultrahigh stocking density (a.k.a., mob grazing) is proposed as a management tool that results in greater harvest efficiency, animal performance, aboveground plant production, species richness, and soil carbon content. The study objective was to determine grazing treatment, haying, or non-defoliated control effects on forage utilization, aboveground production, animal performance, and soil properties. In 2010, 25 ha of Sandhills meadow were divided into 2 replications of 3 grazing, a hay, and control treatment. Grazing treatments were a 120-pasture rotation with one grazing cycle (mob), a 4-pasture rotation with one cycle (4PR1), and a 4-pasture rotation with two cycles (4PR2) at stocking …
The Impact Of Ideology On Lexical Borrowing In Arabic: A Synergy Of Corpus Linguistics And Cda, Sami Hamdi
The Impact Of Ideology On Lexical Borrowing In Arabic: A Synergy Of Corpus Linguistics And Cda, Sami Hamdi
Language, Literacy, and Sociocultural Studies ETDs
Lexical borrowing is a natural outcome of language contact and one source of neologisms. The traditional view of lexical borrowing explains it as motivated mainly by lexical need or prestige where loans in the recipient language have more or less similar if not identical meanings with the borrowing language. Linguistic adaptation has been often seen grammatically based where grammarians or linguists assume the major task of nativizing foreign terms. This is typical in many studies on linguistic borrowing in Arabic while a secondary attention is given to semantic, sociolinguistic, and educational perspectives. The present study approached lexical borrowing as more …
Viral Prevalence Among Social Bees In Different Landscapes, Tugce Karacoban
Viral Prevalence Among Social Bees In Different Landscapes, Tugce Karacoban
Department of Entomology: Dissertations, Theses, and Student Research
Honey bees and wild bees provide important pollination services to numerous crops and native plants. In recent years, declines in bee populations have highlighted the importance of the ecological services they provide and the need for more research into the reasons for their decline. Currently, many conservation efforts to mitigate bee losses include increasing forage and habitat, however, there is growing concern over the role interspecific pathogen transmission plays in bee decline. Viruses commonly found in honey bees may be transmitted and pose a threat to other bee species when bees come together at foraging sites. To elucidate the impact …
Spatial And Temporal Structure Of A Canid Community In Nebraska, Lucia Corral Hurtado
Spatial And Temporal Structure Of A Canid Community In Nebraska, Lucia Corral Hurtado
School of Natural Resources: Dissertations, Theses, and Student Research
Understanding patterns of space-use by individuals, their distribution, and how they coexist with ecologically similar species is crucial to address various issues in ecology, evolution, conservation biology, and wildlife management. However, the study of such patterns challenging because the relationship among species and their environment is shaped by multiple ecological processes, many of which are acting at different scales, often in a hierarchical manner. In the Canidae family, for instance, where interference competition appears critical, larger species such as coyotes (Canis latrans), can often affect smaller species, such as red fox (Vulpes vulpes) and swift fox …
Relationships Among Biodiversity Dimensions Of Birds In Nebraska, Nadejda Mirochnitchenko
Relationships Among Biodiversity Dimensions Of Birds In Nebraska, Nadejda Mirochnitchenko
School of Natural Resources: Dissertations, Theses, and Student Research
Biological diversity, or biodiversity, is a multi-dimensional concept that can be decomposed to measure information about taxonomic, phylogenetic, and functional variation within communities. Although the dimensions of biodiversity are interrelated, the assumption that measuring one dimension of diversity can inform about patterns in another dimension does not necessarily follow from theory or empirical study. The relationships among biodiversity dimensions is not well understood, nor how differences among dimensions could influence conservation decision making. Using the avian community as a study system, we explored the relationships of breadth metrics from the taxonomic, phylogenetic, and functional dimensions among each other and across …
Managing For Vegetation Heterogeneity On Rangelands: An Exploration Of Rancher Attitudes, Stephanie Marie Kennedy
Managing For Vegetation Heterogeneity On Rangelands: An Exploration Of Rancher Attitudes, Stephanie Marie Kennedy
School of Natural Resources: Dissertations, Theses, and Student Research
Grasslands provide food, fiber, and numerous ecosystem services to human populations as well as habitat for wildlife. They are also some of the most endangered ecosystems in the world because of their productive soils and open topography. This problem is exacerbated by the accelerating conversion of grassland to cropland and encroaching trees and shrubs. The quality of remaining grasslands will be of increasing importance because of the biodiversity and vital ecosystem services they provide. Heterogeneity is a term specific to rangeland science that is illustrative of grassland health. Grassland species require very specific and differing habitats and without the variation …
The Biological Significance And Utility Of Feeding By Dermestes Maculatus, Braymond Adams
The Biological Significance And Utility Of Feeding By Dermestes Maculatus, Braymond Adams
School of Natural Resources: Dissertations, Theses, and Student Research
With their efficient feeding habits and tolerance to very low moisture and humidity, beetles in the Family Dermestidae are especially adapted to variable environments and habitats. Dermestid cultures have been in use since 1922 in cleaning tissue and flesh from bones, and proven benefit in multiple fields, including zoology, ornithology, and forensics. Dermestid feeding behaviors when coupled with known life stage and insect succession information aids in providing significant entomological evidence. However, the feeding activities of insects, like those of vertebrate scavengers and predators, change remains and may leave artifacts that can be sometimes be difficult to assign to a …
Role Of Misclassification Estimates In Estimating Disease Prevalence And A Non-Linear Approach To Study Synchrony Using Heart Rate Variability In Chickens, Dola Pathak
Department of Statistics: Dissertations, Theses, and Student Research
Infectious disease assays can be imperfect. When estimating disease prevalence, these imperfections are accounted for by incorporating assay sensitivity and specificity into point and variance estimates. Unfortunately, these accuracy measures are often treated as fixed constants, rather than acknowledging that they are estimates from an assay validation process. The purpose of this study is to show the detrimental effect of not taking into account this sampling variability when samples are obtained through group testing (aka, pooled testing). We show that confidence interval coverage can dramatically decline as the sample size increases for the main sample of interest. As a remedy …
Maternal N-3 Polyunsaturated Fatty Acids Supplementation Potentiates Brown Adipose Tissue Development And Reduces The Risk Of Childhood Obesity, Rong Fan
Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research
Brown adipose tissue (BAT) is a crucial regulator in energy expenditure by dissipating energy in the form of heat through mitochondrial uncoupling protein 1 (UCP1). Previously, we demonstrated that n-3 PUFA (Omega-3 Polyunsaturated Fatty Acids) increase brown adipogenesis by miRNA-mediated epigenetic mechanisms. Given that BAT is formed at the late stage of pregnancy, we hypothesized prenatal exposure of n-3 PUFA through maternal nutrition potentiates BAT development. To test this hypothesis, Female C57BL/6 mice were fed a diet containing n-3 PUFA (3%) derived from fish oil (FO), or an isocaloric diet devoid of n-3 PUFA (Cont), and same diet was maintained …
Cod's Mac Lab: Giving Life To A Space, Jason Krzysztofiak
Cod's Mac Lab: Giving Life To A Space, Jason Krzysztofiak
The Prairie Light Review
No abstract provided.
The Effects Of Diet And Mating System On Reproductive (And Post‐Reproductive) Life Span In A Freshwater Snail, Josh R. Auld
The Effects Of Diet And Mating System On Reproductive (And Post‐Reproductive) Life Span In A Freshwater Snail, Josh R. Auld
Biology Faculty Publications
The length of the reproductive life span, along with the number/frequency/magnitude of reproductive events, quantifies an individual’s potential contribution to the next generation. By examining reproductive life span, and distinguishing it from somatic life span, we gain insight into critical aspects of an individual’s potential fitness as well as reproductive and somatic senescence. Additionally, differentiating somatic and reproductive life spans can provide insight into the existence of a post‐reproductive period and factors that shape its duration. Given the known importance of diet and mating system on resource allocation, I reared individual freshwater snails (Physa acuta) from 22 full‐sib families under …
Financial Inclusion And People Living With Disabilities (Plwds) In Nigeria: A Disaggregated Analysis, Kingsley Imandojemu, Akinlosotu Nathaniel Toyosi, Odigie Joseph Ndidi
Financial Inclusion And People Living With Disabilities (Plwds) In Nigeria: A Disaggregated Analysis, Kingsley Imandojemu, Akinlosotu Nathaniel Toyosi, Odigie Joseph Ndidi
Bullion
This study investigated the level of financial inclusion and people living with disabilities (PLWDS) in Nigeria. The disaggregated analysis was employed in investigating the level of financial inclusion of PLWDs across the geopolitical zones in Nigeria. The instrument used to collect data was titled: Financial Inclusion of People living with Disability Survey Inventory (FIPWIDSI). The construct validity of the instrument was ensured using the Principal Component Analysis (PCA).The internal consistency was verified using Cronbach's alpha technique. Descriptive and influential statistics, Mean and standard deviation, Analysis of Variance (ANOVA) and Sidak multiple mean comparison Post Hoc test were employed for data …
Population Genetics And Desiccation Stress Of Porphyra Umbilicalis Kützing In The Gulf Of Maine, Yuanyu Cao
Population Genetics And Desiccation Stress Of Porphyra Umbilicalis Kützing In The Gulf Of Maine, Yuanyu Cao
Doctoral Dissertations
The red alga Porphyra umbilicalis Kützing is an ecologically and economically important marine macroalga in the Northern Atlantic. Porphyra umbilicalis has a broad distribution within the North Atlantic. In the Northeast Atlantic, it is dioecious and reproduces both sexually and asexually, while in the Northwest Atlantic only asexual reproduction has been observed. As a high intertidal alga, P. umbilicalis regularly experiences desiccation and rehydration cycles with the tidal cycles, so it has high tolerance towards various abiotic stresses. The present work attempts to understand the population structure in asexual populations of P. umbilicalis in the Gulf of Maine by applying …
Addressing The Nitrogen Challenge: Footprint Tools And On-Farm Solutions, Allison M. Leach
Addressing The Nitrogen Challenge: Footprint Tools And On-Farm Solutions, Allison M. Leach
Doctoral Dissertations
Nitrogen management presents a unique dilemma: We must use nitrogen to grow our food and sustain life on earth, but excess reactive nitrogen that accumulates in the environment contributes to a cascade of negative impacts to human and ecosystem health. Addressing this nitrogen challenge will require a suite of solutions. This dissertation presents and explores three nitrogen management strategies: 1) The first ever integrated carbon and nitrogen footprint tool for campus sustainability management; 2) Exporting compost to improve a farm’s nitrogen efficiency; and 3) Methods for reducing gas emissions from aerated static pile heat recovery composting.
Nitrogen footprint tools connect …
A Review Of Attention, Memory, Word Finding, And Executive Function To Support Client Rehabilitation In A Group Therapy Setting, Anna Uftring, Michelle Estand, Annie Heineman, Samantha Marusiak
A Review Of Attention, Memory, Word Finding, And Executive Function To Support Client Rehabilitation In A Group Therapy Setting, Anna Uftring, Michelle Estand, Annie Heineman, Samantha Marusiak
Graduate Independent Studies - Communication Sciences and Disorders
This paper is a review of attention, memory, word finding, and executive function to support individuals with deficits in these areas seen in a rehabilitative speech-language therapy setting. Each chapter contains a definition of the domain and describes the subdomains included. The chapters also include the neurology associated with the domain and common disorders that include deficits in the areas of attention, memory, word finding, and executive functioning. At the end of each chapter, recommended treatment principles are provided to guide therapy with each domain. This paper was created to accompany a therapy manual titled “Providing Connections Through Group Therapy” …
Legacy- December 2018, South Carolina Institute Of Archaeology And Anthropology--University Of South Carolina
Legacy- December 2018, South Carolina Institute Of Archaeology And Anthropology--University Of South Carolina
SCIAA Magazine - Legacy & PastWatch
Contents:
A Tribute to Elizabeth “Betty” Hamilton Stringfellow (November 14, 1921-May 18, 2017..p. 1
Director’s Notes…p. 2
Sergeant York Battlefield Archaeology Study Published…p. 2
Please Welcome Stacey Young, New Director of the Applied Research Division at SCIAA…p. 3
Hidden Under Our Feet: The Broad River Trenching Project…p. 10
Animals Used at Spanish Mount…p. 12
Submerged: Underwater Archaeology of South Carolina: Hands-On Interaction with 8th Graders…p. 15
6th Annual Arkhaios Cultural Heritage and Archaeology Film Festival- Columbia, SC- October 12-14, 2018…p. 19
ART/SCIAA Donors Update August 2017-December 2018…p. 22
Levels Of Par-1 Kinase Determine The Localization Of Bruchpilot At The Drosophila Neuromuscular Junction Synapses., Kara R. Barber, Martin Hruska, Keegan M. Bush, Jade A. Martinez, Hong Fei, Irwin B. Levitan, Matthew B. Dalva, Yogesh P. Wairkar
Levels Of Par-1 Kinase Determine The Localization Of Bruchpilot At The Drosophila Neuromuscular Junction Synapses., Kara R. Barber, Martin Hruska, Keegan M. Bush, Jade A. Martinez, Hong Fei, Irwin B. Levitan, Matthew B. Dalva, Yogesh P. Wairkar
Farber Institute for Neuroscience Faculty Papers
Functional synaptic networks are compromised in many neurodevelopmental and neurodegenerative diseases. While the mechanisms of axonal transport and localization of synaptic vesicles and mitochondria are relatively well studied, little is known about the mechanisms that regulate the localization of proteins that localize to active zones. Recent finding suggests that mechanisms involved in transporting proteins destined to active zones are distinct from those that transport synaptic vesicles or mitochondria. Here we report that localization of BRP-an essential active zone scaffolding protein in Drosophila, depends on the precise balance of neuronal Par-1 kinase. Disruption of Par-1 levels leads to excess accumulation of …
Peer Relationships, Gut Microbiota, And Health In Emerging Adulthood, Erin Quinn Austin
Peer Relationships, Gut Microbiota, And Health In Emerging Adulthood, Erin Quinn Austin
Psychology Dissertations - Archive
Research has consistently shown that chronic stress has negative effects on overall physical and psychological wellbeing across the lifespan. The biological mechanisms through which stress exerts its effects on the body and the mind includes the recently discovered microbiome-gut-brain axis, the bidirectional communication between the brain and the enteric nervous system that is modulated by the microorganisms residing within the gastrointestinal tract. This dissertation examined the impact chronic psychosocial stress (e.g., peer victimization, daily hassles) had on gut diversity and the relative abundance specific bacterial groups in a diverse sample of emerging adults (N = 126, Mean age = 20.07). …
Sanctuary: A Virtual-Reality, Immersive-Environment Mobile Application To Promote Mindfulness, Meditation, And Relaxation, Amanda Caroline Smoak
Sanctuary: A Virtual-Reality, Immersive-Environment Mobile Application To Promote Mindfulness, Meditation, And Relaxation, Amanda Caroline Smoak
All Theses
The World Health Organization calls stress the health epidemic of the twenty-first century [40]. Finding ways to manage stress – not just for our own health, but also for the health of our communities and children – is one of our most significant challenges for wellness. Virtual-reality (VR) therapy is the use of stimulated, interactive, and immersive environments as a tool for physical and psychological healthcare applications [31]. VR therapy and mindfulness practices have both been shown to alleviate stress and anxiety. The mobile application detailed here attempts to aid in stress reduction using virtual-reality therapy by immersing the user …
Observed Cooking Behaviors Of Families With And Without Childhood Cancer Survivors And The Development Of A Healthy Cooking Assessment Tool, Margaret Pleta Raber
Observed Cooking Behaviors Of Families With And Without Childhood Cancer Survivors And The Development Of A Healthy Cooking Assessment Tool, Margaret Pleta Raber
Dissertations and Theses (Open Access)
Diet is a modifiable risk factor for several cancers and other chronic diseases. Cooking skills are a target for dietary intervention, with much of the general population reporting infrequent and inadequate home preparation of meals. Childhood cancer survivors (CCS) are a population at high risk of several chronic conditions including secondary cancers that may be influenced by home cooking behaviors. We conducted observations of food preparation practices in 29 parents of healthy school-aged children and 11 parents of CCS. Observations included an audio and video recording of one evening meal per family. Parents were asked to wear a small body …
Chagas Disease Awareness Amongst Texas Physicians, Gerardo J. Pacheco
Chagas Disease Awareness Amongst Texas Physicians, Gerardo J. Pacheco
Dissertations and Theses (Open Access)
An estimated 300,000 people in the U.S. are living with Chagas Disease (CD), many of whom may not yet know they are infected. Approximately 20% to 30% of individuals with CD are expected to develop clinical symptoms that may manifest as heart disease and result in death if left untreated. The prevalence of CD in humans is not well understood. Given its asymptomatic manifestation and the rarity in cases seen by physicians in general, CD may be under-recognized by physicians.
The purpose of this research was to explore the understanding and knowledge of CD in Texas HCP populations (cardiologists, infectious …
Collateral Benefits Of Diabetes Self-Management Associated With Self-Administered Outpatient Parenteral Antimicrobial Therapy, Anisha P. Ganguly
Collateral Benefits Of Diabetes Self-Management Associated With Self-Administered Outpatient Parenteral Antimicrobial Therapy, Anisha P. Ganguly
Dissertations and Theses (Open Access)
Self-administered outpatient parenteral antimicrobial therapy (S-OPAT) is a self-care treatment modality in which patients requiring extended courses of intravenous antibiotics are trained to safely self-administer treatment via an indwelling catheter in their home. Many patients seen in the S-OPAT program have a diagnosis of diabetes and present with infections associated with poor glycemic control, including skin and soft-tissue infections and osteomyelitis. Given the degree of patient activation required to successfully complete the S-OPAT process, we hypothesized that participation in this self-care program may benefit patients in self-management of other chronic health conditions, such as diabetes. The study team included Anisha …
Investigation Of Hantavirus And Leptospira As Possible Contributing Factors Of The Unexplained Kidney Disease Epidemic In Nicaragua, Nicole J. Delgado
Investigation Of Hantavirus And Leptospira As Possible Contributing Factors Of The Unexplained Kidney Disease Epidemic In Nicaragua, Nicole J. Delgado
Dissertations and Theses (Open Access)
Throughout Latin America, an epidemic of a kidney disease of an unknown etiology has been occurring since the late 1990s, and this disease is being called “Mesoamerican nephropathy.” Mesoamerican nephropathy predominantly affects male sugarcane workers. In Chichigalpa, Chinandega, Nicaragua, there is sugarcane plantation that is being heavily impacted by the Mesoamerican nephropathy epidemic, and they invited researchers from Baylor College of Medicine to investigate the epidemic. The prospective epidemic investigation began in 2015, and it is an ongoing investigation. Based on the compilation of data collected during the preliminary investigation, our hypothesis is that a possible zoonotic disease, such as …