Digital Commons Network^™

Emotion Socialization And Families Of Children With And Without Adhd., Danielle M. Walerius

Electronic Theses and Dissertations

Emotional competence (EC) represents several distinct emotional skills found to be strongly associated with children’s socioemotional outcomes. EC is thought to develop through a process known as emotion socialization (ES), whereby children’s emotions and emotion-based behaviors are socialized through interactions with parents and/or other primary figures. The present study examined ES across families of children with and without ADHD in order to clarify the role ES plays in the development of EC in typically developing (TD) children versus children more prone to EC impairments due to intrapersonal characteristics (e.g., inattention, disinhibition, etc.). Forty-eight children 5 to 8-years-old (23 with ADHD, …

Pcb-Associated Steatohepatitis And The Role Of Nuclear Receptors., Heather Brooke Clair

Electronic Theses and Dissertations

Metabolic diseases, including fatty liver disease, hyperglycemia, and obesity, result when body systems responsible for managing allostasis (dynamic homeostasis across systems) are pressured beyond their collective compensatory reserve. Nutritional excess contributes to this state, the capacity of which is limited by genetic variation, and failure of one system will gradually lead to pathological overload in the others. Agents which act directly on the communication machinery linking these connected systems can also change the point at which allostatic load becomes allostatic overload. Environmental exposure to polychlorinated biphenyls (PCBs), a class of persistent organic pollutant, is associated with a specific form of …

Role Of Human Arylamine N-Acetyltransferase 1 In Tumorigenesis And Cancer Biology., Marcus William Stepp

Electronic Theses and Dissertations

Human arylamine N-acetyltransferase 1 (NAT1) is a well-known phase II metabolic enzyme that has been associated with carcinogenesis. Its role in the biotransformation of aromatic and heterocyclic amine carcinogens has been investigated for many years, but more recent investigations focus on a possible endogenous role of human NAT1 in cancer initiation and progression. To further explore and understand possible endogenous roles for NAT1, we conducted in vitro enzymatic reactions, in vivo studies using homozygous high (rapid) or low (slow) NAT2 activity congenic F344.WKY rats, and genetically modified human breast cancer cell lines. Human NAT1 and rodent NAT2 hydrolyzed acetyl-coenzyme …

Numerical Investigation Of Drop Impingement On Dry And Wet Surfaces., Yisen Guo

Electronic Theses and Dissertations

In-flight icing due to supercooled large droplets (SLDs) imposes great danger on aviation safety. Because of the large size, SLDs have different characteristics than typical cloud droplets that most icing encounters involve. As a result, SLDs more likely hit the wing surface and move into areas not protected by de-icing devices to form ice, which can lead to loss of lift, increase in drag, altered controllability, and eventually stall and loss of control of the aircraft. The phenomenon of droplet splashing is considered as the most important aspect of the SLD icing accretion problem. Although previous studies have established splashing …

Heterogenization Of Complexes With Redox Active Ligands For Hydrogen Evolution Reaction., Wuyu Zhang

Electronic Theses and Dissertations

Hydrogen fuel is a promising future energy carrier with many applications. Thermodynamically, 1.23 V is needed for the water electrolysis, which is a clean method to generate hydrogen gas. In practice excess potential is required, which is called overpotential, due to kinetic barriers. Catalysts to reduce the overpotential for the hydrogen evolution reaction (HER) include many homogeneous catalysts and heterogeneous catalysts. Heterogenization of homogeneous catalysts on electrode surfaces is an ideal way to study a catalyst by combining homogeneous and heterogeneous study together. In this dissertation, several characterization techniques have been employed, include cyclic voltammetry, linear sweep voltammetry, electrochemical impedance …

Norton Commons, Clifton, And Social Equity : A Neighborhood, Inter-Neighborhood, And Regional Comparison Of New Urbanism And “Old” Urbanism., Aaron J. Stephenson

Electronic Theses and Dissertations

This dissertation examines two paradigms aimed at restoring urban vitality-- grassroots neighborhood revitalization and New Urbanism. New Urbanism is comprised of progressive goals, but unfortunately the relevant literature suggests that these goals have not been achieved. As such, this study focuses upon the degree to which each of these paradigms, New Urbanism and grassroots revitalization, may impact social equity on a spatial level. This dissertation explores this through a comprehensive micro-level comparison of two neighborhoods in Louisville, Kentucky- Clifton and Norton Commons. Clifton is an activist urban neighborhood that has been revitalized in recent decades, to become one of Louisville’s …

Farmscapes : Picturing Land Transformation In Nineteenth-Century America., Eileen L Yanoviak

Electronic Theses and Dissertations

This dissertation examines American farmstead imagery of the nineteenth-century and how those images reflect the environmental history of the North. In this study, images of farms illustrate, through the landscape, the transition from subsistence farming to agribusiness that fundamentally changed American life and the land over the century. By comparing the actual ecological and economic conditions of the farm and farmer to the images depicted by artists, it is possible to see both representations of change and the persistence of the agrarian myth in spite of dramatically different realities. This study focuses on the process of change in the American …

Modeling Effective Work Groups And Teams : An Assessment Of The Inclusion Of Social Value Orientation., Gary Daniel Jones

Electronic Theses and Dissertations

The purpose of this study is to examine research on effective work groups in terms of measurable input characteristics and relevant collective outputs. Antecedents and consequences of group processes are explored; models of work groups and teams are examined and assessed in light of subsequent research. Additionally, social value orientation – a behavioral trait known to predictably influence interpersonal outcomes – is introduced as a concept that is also relevant to group work. A revised model that includes social value orientation as a predictive factor for group productivity is presented and tested. This empirical study is a correlative, quantitative investigation …

Lgbtq+ Nondiscrimination Laws In Kentucky., Christopher M Wales

Electronic Theses and Dissertations

This thesis explores the political and demographic obstacles facing the Fairness movement in Kentucky in regards to local employment protection ordinances for LGBTQ+ persons (Fairness Ordinances). Using case studies on recent Fairness debates in Berea and Bowling Green, this thesis explores the concern some Kentuckians have about LGBTQ+ nondiscrimination ordinances in their communities. From these cases studies, it can be concluded that many of the concerns espoused by opponents of Fairness are simple scare tactics with no evidence supporting their claims. This thesis then utilizes a logistical regression to uncover what demographic characteristics increase the odds of a municipality possessing …

The Relationship Between Positive Behavioral Interventions And Supports In Elementary Schools And Mathematics Achievement., Robert Larry Taylor

Electronic Theses and Dissertations

This causal-comparative study examined the relationship between Positive Behavioral Interventions and Supports (PBIS) and academic achievement in elementary school mathematics. Research has shown that PBIS may help establish a positive school climate, which supports the conditions for effective teaching and learning (Bradshaw, Koth, Bevans, Ialongo, & Leaf, 2008; Horner, Sugai, & Vincent, 2005; Hoy, Tarter, & Bliss, 1990). Accordingly, this study examined variables of particular interest, which were mathematical performance, including mathematical performance by male academic achievement, female academic achievement, and socioeconomic status, based on PBIS implementationThe data used were school-level, 5th grade mathematics achievement scores. Elementary schools, which participated …

Metabolic Regulation Of Myocardial Adaptation To Exercise., Andrew Alan Gibb

Electronic Theses and Dissertations

While the benefits of exercise affect several organs, a significant adaptive response occurs within the heart. Exercise promotes cardiac growth, increases angiogenesis, and enhances cardiac function and these adaptations are associated with a cardioprotective phenotype. Additionally, extensive evidence shows that exercise dynamically regulates myocardial metabolism. This can be attributed to both changes in hormonal stimulation, increases in bioenergetic demand, and the bioavailability of circulating substrates. However, it is unclear whether these changes in metabolism contribute to physiologic cardiac growth. We reason that exercise-induced changes in metabolism are required to balance the catabolic and anabolic reactions needed for growth. Specifically, we …

An Examination Of School Leaders' Preferences For Teacher Applicant Characteristics., Byron Keith Davis

Electronic Theses and Dissertations

Teachers are important to student achievement. The selection of teachers in most schools in the United States is the responsibility of the principal. This study examined preferences of school leaders for teacher applicant characteristics. An exploratory factor analysis of the results (N = 209) of the Preferred Teacher Applicant Characteristics Survey (PTACS) determined four underlying dimension of the PTACS instrument: personal characteristics, professional characteristics, ancillary characteristics, and demographic characteristics. These became the dependent variable in a series of linear multiple regression analyses to examine the relationship between a school’s characteristics – poverty, school performance category, average teacher experience, and the …

Targeting The Major Regulator Of Mitosis., J. Mason Hoffman

Electronic Theses and Dissertations

Mitosis-inhibiting chemotherapeutics (e.g. taxanes) are frequently used to treat multiple cancer types. Recently, there has been much concern about the limited success of these drugs due to resistance and a lack of molecular targets. Thus, there is high demand for new drugs with diverse cellular targets. Targeting the regulators of mitosis is a promising approach. The anaphase promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that controls cell cycle progression at multiple points. The interaction of ANAPC2 and ANAPC11, catalytic core subunits, is necessary for APC/C function. An in silico approach was used to identify compounds predicted to prevent assembly …

Winds Of Courage A Mallet Concerto For Solo Mallets And Wind Ensemble., Ross Elliott

Electronic Theses and Dissertations

Winds of Courage is a motivically-driven composition based on a repeating chordal pattern. Although being written out, the solo mallets parts sound somewhat improvisatory, which is a key element to the part. In a way, the concerto illustrates what it is like to have a crush on someone; where the first movement is getting up the courage to talk to them; the second movement, crying from failing to say what you need to say or not getting up the courage to talk to them, or getting rejected; and the final movement, when things work out in a positive manner, or …

Educating Critically : Challenging The Familiar Contours Of Literacy Teacher Education., Bianca Nightengale-Lee

Electronic Theses and Dissertations

The shifting cultural ecologies of U.S. classrooms emphasize acknowledging difference, accepting diversity, and sustaining both cultural and linguistic plurality (Banks & Banks, 2009; hooks, 1994; Paris 2014). Teacher education programs play an integral role in preparing Pre-Service Teachers (PSTs) with skills, knowledge, and dispositions necessitated by a growing Culturally and Linguistically Diverse (CLD) student population (Cruz, Ellerbrock, Vasquez & Howes, 2014). To enact equitable teaching practices reflective of 21st century students, PSTs need to demonstrate a level of cultural awareness that acknowledges the racially, socially, and politically charged societal structures that shape education for CLD students (Hall & Carlson, 2016). …

Effect Of Total Body Iron On Metabolic Dysfunction Among U.S. Females In The Nhanes 2003-2010, Aged 12-49., Joseph Michael Carhart

Electronic Theses and Dissertations

Experimental and epidemiological studies have reported positive associations between iron parameters and metabolic dysfunction including: Type 2 diabetes mellitus (T2DM) (1-6), metabolic syndrome (7-15), non-alcoholic fatty liver disease (NAFLD) (16-22) and insulin resistance (23,24) with a number of studies showing that reductions in total body iron via dietary modification (e.g., reducing red meat intake) or phlebotomy lead to increases in insulin sensitivity (25), decreases in insulin resistance (26), and reductions in the prevalence of complications associated with T2DM (5, 27), metabolic syndrome (28) and NAFLD (22, 29). Moreover, the risk associated with these outcomes and total body iron differ between …

This Is Just A Phase : The Impact Of Population Structure On Haplotype Phasing And Linkage Disequilibrium Measures At Functional Genetic Sites., Roxanne Kaaren Leiter

Electronic Theses and Dissertations

The block-like structure of the human genome has been the subject of many scientific papers and is of practical significance in large-scale genome-wide association studies. How stringent haplotype block boundaries are within and between populations has been the subject of ongoing debate within human population genetics. This thesis will contribute to the description of universal and population-specific haplotype blocks at functional sites, namely across the IL-10 gene family (including IL-10, IL-19, IL-20 and IL-24), which is involved in a number of immune system processes, and MAPKAP-K2, an adjacent and functionally significant kinase gene. Beyond the description of blocks across these …

Chemoselective Reagents For Derivatization Of Trace--Level Volatile Carbonyl Compounds Using A Microreactor Approach., Mumiye A. Ogunwale

Electronic Theses and Dissertations

Detection and analysis of trace level volatile aldehydes and ketones has become a significant research frontier because of the applicability for environmental monitoring and assessment, noninvasive diseases diagnosis, and in food safety assessment for the US Food and Drug Administration. The number of derivatization reagents for detection of aldehydes and ketones has increased considerably over the last decade. However, the majority of these derivatization reagents are not efficient in derivatizing unsaturated carbonyl compounds due to the presence of electron withdrawing groups adjacent to the reactive functional moieties making them insufficiently nucleophilic. The analysis of trace-level carbonyl compounds challenges existing analytical …

The Art Of Silence., Lydia Anne Kowalski

Electronic Theses and Dissertations

This dissertation argues that the role of silence as essential to experience the full aesthetic beauty of art in a museum setting. Museums have changed their focus due to socio-economic and financial pressures. They have changed from silent “temples” for art conservation and exhibition to places for interactive art education, entertainment, and social gathering. The results of these changes have been both positive and negative. Attendance has increased, enhancing the museum experience, engaging more diverse audiences in museum activities, and dispelling the “elitist” image of the museum. These changes, however, have resulted in the loss of a silent space to …

Evaluating Work Place Wellness In Greater Louisville's Technology Organizations : A Case Study., Andrew L. Mccart

Electronic Theses and Dissertations

Employers in the Southern Indiana and Greater Louisville region are looking for strategies to help them become a healthier workplace. Many employers see the expense of paying for an unhealthy workforce and they are looking to limit these expenses. The purpose of the study is to determine the state of workplace wellness activities in organizations in Southern Indiana and Greater Louisville. Due to the poor health statuses of Indiana and Kentucky, 39th and 45th, respectively, this study is significant for a number of stakeholders in our area. The purpose of this case study was to understand the state of health …

Design, Analysis, And Application Of A Cellular Material/Structure Model For Metal Based Additive Manufacturing Process., Shanshan Zhang

Electronic Theses and Dissertations

Powder bed fusion additive manufacturing (PBF-AM) has been broadly utilized to fabricate lightweight cellular structures, which have promising potentials in many engineering applications such as biomedical prosthesis, aerospace, and architectural structures due to their high performance-to-weight ratios and unique property tailorabilities. To date, there is still a lack of adequate understanding of how the cellular materials are influenced by both the geometry designs and process parameters, which significantly hinders the effective design of cellular structures fabricated by PBF-AM for critical applications. This study aims to demonstrate a cellular structure design methodology that integrates geometrical design and process-material property designs. Utilizing …

Fused Filament Fabrication 3d Printing Using Low-Melting Alloys., Nirupama Warrier

Electronic Theses and Dissertations

Fused Filament Fabrication (FFF) 3D printing technology has been a popular method of creating prototypes using plastics in the timeliest and most affordable manner for electronic, automotive, and biomedical applications. 3D printing of metals and alloys using FFF technology could provide low-cost alternatives and solutions to the Laser-Powder Bed Fusion Process (L-PBF) and Binder Jetting processes (BJ). In current work, low melting alloys have been used as a starting material and evaluated for FFF 3D printing using two methodologies. In the first methodology, Sn60Bi40 alloy in the form of wire was used as the feedstock for FFF extrusion and process …

Challenging The Self : An Examination Of The Media's Role In Creating Idealized Bodies And The Artists That Challenge Them., Jessica Oberdick

Electronic Theses and Dissertations

Seeking to understand the media’s influence over society, and the way the media motivate us to conform to specific ideals, this thesis focuses on how female bodies in particular are consistently idealized and objectified in mainstream media. Through television, print, and the internet, the media serve as our world’s main means of mass communication. Noting this, this text seeks to understand the female body’s historical objectification through art history and genres of the nude, how this has transferred to contemporary media, and finally states that these stereotypes and norms can be challenged through the work of contemporary artists. By reclaiming …

Trinity Part One : Food Of The Gods., Thomas Edward Olges

Electronic Theses and Dissertations

A novel of supernatural horror, Trinity begins in the wake of a catastrophe. A young woman, divinely pregnant, has lost both her life and her son in the process of delivery. Three people dear to her—her fiancé, her brother, and a close friend—have found themselves irreparably altered by the experience. Their bodies changed and reality warping around them, the three set off across the country in an attempt to prevent other incursions of the miraculous into our reality. This thesis includes the novel’s introductory scene and its first principle section, “Food of the Gods.”

A Framework For Clustering And Adaptive Topic Tracking On Evolving Text And Social Media Data Streams., Gopi Chand Nutakki

Electronic Theses and Dissertations

Recent advances and widespread usage of online web services and social media platforms, coupled with ubiquitous low cost devices, mobile technologies, and increasing capacity of lower cost storage, has led to a proliferation of Big data, ranging from, news, e-commerce clickstreams, and online business transactions to continuous event logs and social media expressions. These large amounts of online data, often referred to as data streams, because they get generated at extremely high throughputs or velocity, can make conventional and classical data analytics methodologies obsolete. For these reasons, the issues of management and analysis of data streams have been researched extensively …

Material Properties Design Using Simulations And Experiments For Powder Injection Molding Of Lead Zirconate Titanate (Pzt)., Bhushan Pramod Bandiwadekar

Electronic Theses and Dissertations

Powder injection molding (PIM) process simulations can be performed to minimize the number of injection molding experiments by estimating material properties necessary for PIM simulations. In current work, lead zirconate titanate (PZT) powder-polymer binder feedstock was compounded for 45 vol. % and 52 vol. % solids loading. PIM experiments on designed micro-pillar array geometry were performed using 52 vol. % PZT. Using PIM experiments results as basis, PIM simulations were performed on designed micro-pillar array geometries to understand the effectiveness of PIM simulations with the use of estimated feedstock properties in predicting molding behavior that have micro-features. Additionally, PIM simulations …

All-Optical Switching In Ferromagnetic Superlattices., Faren Hoveyda Marashi

Electronic Theses and Dissertations

The unexpected observation of ultrafast demagnetization (UDM) and subsequent time-resolved studies of laser-induced magnetization switching opened a new door to both fundamental physics and technological applications of magnetic materials. All-optical switching (AOS) can be initiated faster than the precession limit, hinting to its potential in increasing the writing speed and data storage density. However, notwithstanding considerable research interest, the mechanism of AOS in ferromagnetic materials remained unclear.

Ferromagnetic superlattices were deposited on glass substrates with e-beam evaporation and sputtering. Magnetization curves were measured in magneto-optical and vibrating sample magnetometer experiments. A femtosecond Ti:S laser was utilized in a writing setup …

The Role Of Kinases And Phosphatases In The Pathobiology Of Porphyromonas Gingivalis., Sarah Whitmore

Electronic Theses and Dissertations

Periodontal diseases result from the interplay between the dysregulation of the host inflammatory response and the actions of a dysbiotic bacterial community. These chronic inflammatory conditions affect persons on a worldwide scale. P. gingivalis is strongly implicated as a key periodontal pathogen in the more severe manifestations of periodontal diseases such as periodontitis. A core element of P. gingivalis pathogenicity is its dysregulation of innate immunity, including suppression of IL-8 production by gingival epithelial cells. The NF-κB family of related transcription factors plays a central role in regulating many important aspects of innate immune responses. NF-κB RelA/p65 homodimers regulate transcription …

An Investigation Of Relationship Correlates And Predictors Of Cultural Adjustment Among Missionaries., Sarah Warren

Electronic Theses and Dissertations

While research on the cultural adjustment of expatriates has existed for decades, information related to the cultural adjustment of missionaries is considerably lacking (Kimber, 2012). Information on missionary cultural adjustment often has been extrapolated from the greater expatriate population, in spite of differences existing between missionaries and other expatriates (Navara & James, 2002; 2005). This study examined the extent to which missionary relationships (with God, individuals from one’s host culture, individuals from one’s home culture, and other missionaries) correlate with and predict cultural adjustment among missionaries. Participants were recruited from the Church of the Nazarene’s Global Mission Department to complete …

Greater London In The 21st Century : Assessing Coastal Flooding Mitigation Preparedness And Regional Population Risk In The Face Of Projected Sea-Level Rise., Nathan K Wright

Electronic Theses and Dissertations

Recent projections of +6-9m sea-level rise (SLR) over the next several decades present many social challenges for coastal regions during the 21^st century. These projections were applied to Greater London, UK as areal interpolated historical census data was overlaid on a 50m DEM alongside a polyline projection of the Thames Barrier. Population was projected to milestones of 2041, 2071, and 2101 using a capped, aggregated growth rate for each polygon while SLR was simulated for 1m, 5m, and 9m scenarios. The Thames Barrier maintained integrity for 1m and 5m scenarios but was breached at 9m. Population continued to increase …