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Copper And Zinc Speciation In The Tamar Estuary, Holly Beverley Clare Pearson

School of Geography, Earth and Environmental Sciences Theses

The chemical speciation of trace metals controls their potential bioavailability and therefore toxicity to exposed organisms. Despite previous studies demonstrating the ameliorative effects of dissolved organic carbon (DOC) on metal toxicity, the effectiveness of ligands from varying sources and of potentially variable composition in controlling speciation has not been studied in detail in estuarine waters. In addition, the effect of DOC on radionuclide contaminants in combination with trace metals has not been investigated in any waters. This is of particular interest in the estuarine environment, where both anthropogenic and natural ligands, and contaminants that pose a potential threat to ecosystem …

Stratigraphic And Geochemical Expression Of Early Cretaceous Environmental Change In Arctic Svalbard, Madeleine Larissa Vickers

School of Geography, Earth and Environmental Sciences Theses

The Arctic is climatically sensitive to global change and therefore climate records from this region are of key importance. Little, however, is known of the state of the Arctic in the traditionally “greenhouse” period of the Cretaceous. Climate conditions are often assumed to have been warm-temperate as evidenced by the presence of conifers and dinosaur trackways on Svalbard and other Arctic localities. However, isotopic evidence for cooling episodes, sequence stratigraphic evidence for interpreted glacio-eustatic sea-level falls, and the presence of more enigmatic deposits such as dropstones and glendonites has led to a re-evaluation of the question of climatic dynamism during …

The Seasonal Cycling And Physico-Chemical Speciation Of Iron On The Celtic And Hebridean Shelf Seas, Antony James Birchill

School of Geography, Earth and Environmental Sciences Theses

Shelf seas represent an important source of iron (Fe) to the open ocean. Additionally, shelf seas are highly productive environments which contribute to atmospheric carbon dioxide drawdown and support large fisheries. The work presented in this thesis describes the seasonal cycle of Fe in the Celtic and Hebridean Shelf Seas, and determines the physico-chemical speciation of Fe supplied from oxic margins. The results from repeated field surveys of the central Celtic Sea showed a nutrient type seasonal cycling of dissolved Fe (< 0.2 µm; dFe), which is surprising in a particle rich shelf system, suggesting a balance of scavenging and remineralisation processes. Coincident drawdown of dFe and nitrate (NO3-) was observed during the phytoplankton spring bloom. During the bloom, preferential drawdown of soluble Fe (< 0.02 µm; sFe) over colloidal Fe (0.02-0.2 µm; cFe) indicated greater bioavailability of the soluble fraction. Throughout summer stratification, it is known that NO3- is drawn down to < 0.02 µM in surface waters. This study revealed that both dFe and labile particulate Fe (LpFe) were also seasonally drawn down to < 0.2 nM. Consequently, it is hypothesised that the availability of Fe seasonally co-limits primary production in this region. At depth both dFe and NO3- concentrations increased from spring to autumn, indicating that remineralisation is an important process governing the seasonal cycling of dFe in the central Celtic Sea. In spring, summer and autumn, distinctive intermediate nepheloid layers (INL) were observed emanating from the Celtic Sea shelf slope. The INLs were associated with elevated concentrations of dFe (up to 3.25 ± 0.16 nM) and particulate Fe (up to 315 ± 1.8 nM) indicating that they are a persistent conduit for the supply of Fe to the open ocean. Typically > 15% of particulate Fe was labile and 60-90% of dFe was in the colloidal fraction. Despite being < 50 km from the 200 m isobath, the concentration of dFe was < 0.1 nM in surface waters at several stations. Broadly, the concentration of nutrients in surface waters described an oligotrophic environment where co-limitation between multiple nutrients, including Fe, appears likely. Over the Hebridean shelf break, residual surface NO3- concentrations (5.27 ± 0.79 µM) and very low concentrations of dFe (0.09 ± 0.04 nM) were observed during autumn, implying seasonal Fe limitation. The dFe:NO3- ratio observed is attributed to sub-optimal vertical supply of Fe relative to NO3- from sub-surface waters. In contrast to the shelf break, surface water in coastal regions contained elevated dFe concentrations (1.73 ± 1.16 nM) alongside low NO3-. Seasonal Fe limitation is known to occur in the Irminger and Iceland Basins; therefore, the Hebridean shelf break likely represents the eastern extent of sub-Arctic Atlantic seasonal Fe limitation, thus indicating that the associated weakening of the biological carbon pump exists over a wider region of the sub-Arctic Atlantic than previously recognised. These key findings demonstrate that the availability of Fe to phytoplankton may seasonally reach limiting levels in temperate shelf waters and that oxic margins persistently supply Fe dominated by colloidal and particulate fractions to the ocean.

Nanoporous Calcium Carbonate-Based Substrates For The Controlled Delivery Of Functional Materials, Charlotte Luanne Victoria Levy

School of Geography, Earth and Environmental Sciences Theses

The overall aim of this project was to study `functionalised' calcium carbonates (FCCs) for use as a carrier for the controlled release of `actives,' by permeation and diffusion, and is being proposed as an environmentally friendly and non-toxic pharmaceutical excipient, nutraceutical, and flavour carrier. The delivery of a drug to its target site in the appropriate amount and time-frame in order for it to have a controlled release effect whilst achieving the maximum therapeutic effect remains a topic of design and development for novel drug delivery systems. FCCs encompass a family of new pharmaceutical excipients in which the conditions of …

Despite Efforts, International Environmental Law Is Aspirational Rather Than Successful In Its Contribution To The Protection Of The Global Environment And In The Fight Against Climate Change, Lydia Scambler

The Plymouth Law and Criminal Justice Review

The 1972 United Nations Conference on the Human Environment2 (Stockholm Conference) was the first of many international negotiations to consider the effects of anthropogenic interference with the environment, including chemical pollution and climate change. The Conference and its corresponding declaration recognised customary International Environmental Law (IEL) principles, such as the precaution and prevention principles, and has no doubt been a catalyst for an increased awareness of environmental issues throughout the globe, thus influencing domestic environmental legal systems. The UN climate regime can therefore be seen not only as a source of international law, but as an influence on national and …

Editorial, Kim Stevenson, Lesley Simmonds, Jason Lowther

The Plymouth Law and Criminal Justice Review

No abstract provided.

Criminal Law In The 21st Century, Lord Leveson

The Plymouth Law and Criminal Justice Review

No abstract provided.

Review Of The 1st Annual Conference Of The Refugee Law Initiative And The Refugee Family Reunion Project, Rosie Brennan

The Plymouth Law and Criminal Justice Review

No abstract provided.

There Isn't A Town, Village Or Hamlet In Which Children Are Not Being Sexually Exploited', Safeguarding Our Children: How Effective Are Uk Responses To Child Sexual Exploitation?Â, Danielle Coffey

The Plymouth Law and Criminal Justice Review

The purpose of this research project was to explore the effectiveness of UK responses to the crime of child sexual exploitation (CSE). In order to do this, I interviewed a number of professionals working on the frontline with varying degrees of experience from a range of perspectives. The data collected explored current responses to CSE, how effective these responses are, changes in how CSE manifests, multi-agency collaboration, as well as recommendations for improving responses. Recent high profile cases of CSE have moved exploitation to the peak of many agencies agendas; finally giving the thousands of children and young people the …

Don't Think, Just Drink!': An Ethnographic Study Into Why Young People Engage With Alcohol-Fuelled Leisure Markets Of The Night-Time Economy, Sam Barnes

The Plymouth Law and Criminal Justice Review

Consumption and consumerism are now accepted as being fundamental contexts for the construction of youth lifestyle in post-modern society. This research is a critical exploration of why young people consume alcohol in a manner that can go beyond 'pleasure', to the painful realms of jouissance. This research draws on various disciplines utilising a deviant leisure perspective in order to explore the broader harms that lie beneath the surface of commodified leisure, which have become culturally acceptable and normalised in today's society. Through the use of ethnographic research, utilising observations and unstructured interviews, this project critically explores the significance of alcohol-fuelled …

The Seigniory Of Sark And The Duchy Of Cornwall: Similarities And Differences Including Observations On The Isles Of Scilly, John Kirkhope

The Plymouth Law and Criminal Justice Review

No abstract provided.

To What Extent Are The Economic And Environmental Aspects Of Climate Change Regulation Actually Balanced?, Louise Dale

The Plymouth Law and Criminal Justice Review

This paper explores current international and EU legal instruments to combat climate change, assessing their efficiency from an environmental and economic perspective. It attempts to decipher whether an obvious imbalance is present in relation to the growth of the economy overshadowing regulations imposed to reduce rapid environmental degradation. In the penultimate section a potential future instrument is considered that may alleviate the climate crisis and conquer the economic and environmental divide. This paper will conclude that the incorporation of business, industry and governments in the implementation of future climate regulation is critical to their success in climate stabilisation through substantial …

Piracy And Plymouth: Privateering, Profiting And Policing, Plymouth Law School's Contribution To The Esrc Festival Of Social Science 2016, Dale Teobald

The Plymouth Law and Criminal Justice Review

No abstract provided.

Slavery, Dark Tourism And Deviant Leisure At The American Society Of Criminology In New Orleans, Thomas Raymen

The Plymouth Law and Criminal Justice Review

No abstract provided.

Consent, Knowledge And Precaution: A Critical Analysis Of The Criminalisation Of The Reckless Transmission Of Hiv And Other Serious Diseases, James Stone

The Plymouth Law and Criminal Justice Review

This article examines the criminalisation of the reckless transmission of disease in England and Wales. The defence of consent to bodily harm and the principle of informed consent are crucial to the foundations of this discussion. This defence gives an HIV infected party freedom to behave recklessly and rely on the knowledge of the victim as a defence for their reckless behaviour. The criminal recklessness of an HIV infected party has also been argued to be negated by the careful use of precautionary measures during sexual activity. This means that an infected party can engage in sexual activity in the …

Pengujian Trilemma Conditions Pada Perekonomian Indonesia, Mela Yunita, Noer Azham Achsani, Lukytawati Anggraeni

Jurnal Ekonomi dan Pembangunan Indonesia

The key challenge for monetary policy in emerging market countries is simultaneously maintain monetary independence, exchange rate stability, and join with financial integration. This research explain the interaction of monetary policy in Indonesia over time to answer those three challenge with a Trilemma conditions. This research evaluate the Bank Indonesia’s decision to change the exchange rate regime and applied ”inflation targeting”. The methods include to build the Trilemma’ index and testing the Trilemma with constant regression. The results indicate that Bank Indonesia has tradeoff in determining the combination of monetary policy objectives. Tradeoff for Bank Indonesia more heavy under free …

Keberadaan Ritel Modern Dan Dampaknya Terhadap Pasar Tradisional Di Dki Jakarta, Dianur Hikmawati, Chaikal Nuryakin

Jurnal Ekonomi dan Pembangunan Indonesia

This study aimed to analyze the impact of modern retail coexistence with traditional retail on traditional retail’s performance. Our observation is the 153 markets PD Pasar Jaya spread across DKI Jakarta and the modern retails (minimarkets, supermarkets, hypermarkets) location based on the retail zoning policy of Jakarta Regional Regulation No. 2/2002. This study used number of traditional retailers as a proxy of performance variable. The regression results indicate a non linear relationship between the number of modern retails–especially supermarket–and traditional retails performance in which the coexistence of one supermarket is positive for traditional market performance and negative afterwards.

Clinical Consultations And Investigations Before And After Discontinuation Of Endocrine Therapy In Women With Primary Breast Cancer, Derrick Lopez, Anna Kemp-Casey, Christobel Saunders, Elizabeth Roughead, Frances Boyle, Max Bulsara, David Preen

Health Sciences Papers and Journal Articles

Objective: Although clinical trials recommend that women with hormone-dependent primary breast cancer remain on endocrine therapy for at least 5 years, up to 60% discontinue treatment early. We determined whether these women had consulted with clinicians or had investigations for cancer recurrence or metastasis around the time they discontinued endocrine therapy, and whether clinical contact continued after discontinuation.

Methods: We performed case-control and cohort studies of women from the 45 and Up Study who were diagnosed with invasive primary breast cancer between January 2003 and December 2008, and who had ≥12 months of anastrozole, exemestane, letrozole or tamoxifen subsequently dispensed. …

Health Economics Of Targeted Intraoperative Radiotherapy (Targit-Iort) For Early Breast Cancer: A Cost-Effectiveness Analysis In The United Kingdom, Anil Vaidya, Param Vaidya, Brigitte Both, Chris Brew-Graves, Max Bulsara, Jayant S. Vaidya

Health Sciences Papers and Journal Articles

Objective: The clinical effectiveness of targeted intraoperative radiotherapy (TARGIT-IORT) has been confirmed in the randomised TARGIT-A (targeted intraoperative radiotherapy-alone) trial to be similar to a several weeks’ course of whole-breast external-beam radiation therapy (EBRT) in patients with early breast cancer. This study aims to determine the cost effectiveness of TARGIT-IORT to inform policy decisions about its wider implementation. Setting TARGIT-A randomised clinical trial (ISRCTN34086741) which compared TARGIT with traditional EBRT and found similar breast cancer control, particularly when TARGIT was given simultaneously with lumpectomy.

Methods: Cost-utility analysis using decision analytic modelling by a Markov model. A cost-effectiveness Markov model was …

The Most Important "Factor" In Producing Clubhead Speed In Golf, C Joyce

Health Sciences Papers and Journal Articles

Substantial experiential research into x-factor, and to a lesser extent crunch-factor has been undertaken with the aim of increasing clubhead speed. However, a direct comparison of the golf swing kinematics associated with each ‘factor’ has not, and possible differences when using a driver compared to an iron. Fifteen low handicap male golfers who displayed a modern swing had their golf swing kinematic data measured when hitting their own driver and five-iron, using a 10-camera motion analysis system operating at 250 Hz. Clubhead speed was collected using a validated launch monitor. No between-club differences in x-factor and crunch-factor existed. Correlation analyses …

Neuromuscular Training Improves Lower Extremity Biomechanics Associated With Knee Injury During Landing In 11-13 Year Old Female Netball Athletes, A Hopper, E Haff, C Joyce, R Lloyd, G Haff

Health Sciences Papers and Journal Articles

The purpose of this study was to examine the effects of a neuromuscular training (NMT) program on lower-extremity biomechanics in youth female netball athletes. The hypothesis was that significant improvements would be found in landing biomechanics of the lower-extremities, commonly associated with anterior cruciate ligament (ACL) injury, following NMT. Twenty-three athletes (age = 12.2 ± 0.9 years; height = 1.63 ± 0.08m; mass = 51.8 ± 8.5 kg) completed two testing sessions separated by 7-weeks and were randomly assigned to either a experimental or control group. Thirteen athletes underwent 6-weeks of NMT, while the remaining 10 served as controls and …

Tumour-Infiltrating Regulatory T Cell Density Before Neoadjuvant Chemoradiotherapy For Rectal Cancer Does Not Predict Treatment Response, Melanie J. Mccoy, Chris Hemmings, Chidozie C. Anyaegbu, Stephanie J. Austin, Tracey F. Lee-Pullen, Timothy J. Miller, Max K. Bulsara, Nikolajs Zeps, Anna K. Nowak, Richard A. Lake, Cameron F. Platell

Health Sciences Papers and Journal Articles

Neoadjuvant (preoperative) chemoradiotherapy (CRT) decreases the risk of rectal cancer recurrence and reduces tumour volume prior to surgery. However, response to CRT varies considerably between individuals and factors associated with response are poorly understood. Foxp3+ regulatory T cells (Tregs) inhibit anti-tumour immunity and may limit any response to chemotherapy and radiotherapy. We have previously reported that a low density of Tregs in the tumour stroma following neoadjuvant CRT for rectal cancer is associated with improved tumour regression. Here we have examined the association between Treg density in pre-treatment diagnostic biopsy specimens and treatment response, in this same patient cohort. We …

The Presumptions Of Classical Liberal Constitutionalism, Matthew J. Lindsay

All Faculty Scholarship

Richard A. Epstein’s The Classical Liberal Constitution is an imposing addition to the burgeoning body of legal scholarship that seeks to “restore” a robust conception of economic liberty and limited government to its rightful place at the center of American constitutionalism. Legislators and judges operating within a “classical liberal conception of government,” Epstein explains, would approach skeptically “[a]ll [regulatory] proposals that deviate from the basic common law protections of life, liberty, and property.” Classical liberal constitutional courts would thus renounce the toothless rational basis review of the post-New Deal “progressive mindset,” and instead subject to exacting scrutiny the government’s “purported …

Implementing A First-Year Research Assessment, Savanna L. Nolan

All Faculty Scholarship

University of Baltimore Law librarians do not have a formal role in teaching legal research, but are frequent guest lecturers and recognized research experts. As such, we volunteered to administer UB's first summative assessment in accordance with the recent implementation of ABA Standard 314. This poster shows the steps taken to design, execute, and grade this legal research assessment, as well as how we reported the results to stakeholders.

The assessment had an objective true/false and multiple-choice section, and a subjective essay question. The librarians selected objective questions considering the core legal research competencies identified by RIPS-SIS following the MacCrate …

The Persistence Of The Confederate Narrative, Peggy Cooper Davis, Anderson Francois, Colin Starger

All Faculty Scholarship

Ever since the United States was reconstituted after the Civil War, a Confederate narrative of states’ rights has undermined the Reconstruction Amendments’ design for the protection of civil rights. The Confederate narrative’s diminishment of civil rights has been regularly challenged, but it stubbornly persists. Today the narrative survives in imprecise and unquestioning odes to state sovereignty. We analyze the relationship, over time, between assertions of civil rights and calls for the protection of local autonomy and control. This analysis reveals a troubling sequence: the Confederate narrative was shamefully intertwined with the defense of American chattel slavery. It survived profound challenges …

Comment On “The Empirical Basis For Antitrust: Cartels, Mergers, And Remedies”, John M. Connor, Robert H. Lande

All Faculty Scholarship

In this journal, James Langenfeld critically reviewed four of the present authors’ articles that analyze the size of cartel overcharges and their antitrust policy implications. In this comment, we explain why we believe Langenfeld errs in his criticism of our work. In particular, this comment discusses the variation in research quality of the sources used to compile a large sample of historical cartel overcharges; the advisability of trimming outliers or large estimates from the sample; alleged publication bias; why our 25% median estimate is much more likely to be correct than the US Sentencing Guideline’s 10% presumption; and the implications …

Parallel State, Gregory Dolin, Irina D. Manta

All Faculty Scholarship

Alternatively glamorized and reviled, Rio de Janeiro’s shantytowns, known as “favelas,” have become a fixture of the city’s architecture and life. It is estimated that about a million and a half people reside in these informal settlements that are scattered in the center and outskirts of Brazil’s second-largest metropolitan area. Operating in the shadow of the law and lacking formal ownership title, favela residents have constructed an intricate set of informal rules to buy, sell, rent, and bequeathe property that is often administered by the residents’ associations of individual neighborhoods, which also assist in mediating related conflicts. While largely untested …

Book Review: The History Of The Death Penalty In Colorado, John Bessler

All Faculty Scholarship

No abstract provided.

The Diversity Rationale For Affirmative Action In Military Contracting, Hugh Barrett Mcclean

All Faculty Scholarship

No abstract provided.

Unconventional Refugees, Elizabeth Keyes

All Faculty Scholarship

Refugees are a flash point for political divisions in the United States and abroad. The enormous personal, moral, and legal challenges posed by the displacement of refugees around the world reveal the dire inadequacies of our current policies toward refugee protection. Children running to border agents at the U.S. southern border are treated as a security threat to be deterred, instead of a vulnerable population needing some level of protection. The numbers of people seeking safety in the United States, while not objectively high, places further strain on an already under-resourced and heavily burdened immigration system, which at the end …