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2017

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Infrastructure, Urban Sprawl, And Naturally-Occurring Asbestos: An Ontological Thought Model For Wicked And Saving Technologies, Shane Ray Epting Dec 2017

Infrastructure, Urban Sprawl, And Naturally-Occurring Asbestos: An Ontological Thought Model For Wicked And Saving Technologies, Shane Ray Epting

Arts, Languages and Philosophy Faculty Research & Creative Works

Recently, geologists in Southern Nevada discovered new deposits of naturally occurring asbestos and microscopic fibers in rocks and soil. The danger is that inhaling them can lead to mesothelioma. One problem is that this rare cancer often takes decades to manifest. This discovery abruptly stalled a highway project near Las Vegas. Due to this condition, management developed numerous protocols to keep workers safe. Using this case as a "thought model," the author challenges an established way of categorizing kinds of technologies as they relate to the concept of being. In turn, this thought model reveals that climate change alters the …

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Growing Up In Society - A Historical Social Psychology Of Childhood, Nr Gabriel Dec 2017

Growing Up In Society - A Historical Social Psychology Of Childhood, Nr Gabriel

Plymouth Institute of Education

Abstract: This paper develops a historical social psychology that can be used to understand young children’s social development. It compares the theoretical frameworks of three of the most important relational thinkers in the 20th century – Norbert Elias, Pierre Bourdieu, and Erich Fromm – to shed light on their attempts to integrate the insights of psychoanalysis into their sociological perspectives. I begin by exploring Bourdieu’s “uneasy” relationship with psychoanalysis, arguing that this has led to a less than successful quest by his followers for bridging concepts that can further develop the concept of social habitus. Fromm, one of the foremost …

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Student Success Behaviors And Gender: Exploring The Impact On First-Year Students, Sarah Ramage Dec 2017

Student Success Behaviors And Gender: Exploring The Impact On First-Year Students, Sarah Ramage

Graduate Theses, Dissertations, and Capstones

College demographics are rapidly evolving, and one area of concern is the enrollment and retention rates of male students. The National Center for Educational Statistics reported that in 2010, 57 percent of undergraduate students were female (Weaver-Hightower, 2010). The same report stated that the percentage was projected to grow to 59 percent by 2018 (Weaver-Hightower, 2010). Between 1997 and 2007, female enrollment has risen dramatically faster than male enrollment, with a 29 percent jump in 10 years. Male enrollment increased by 22 percent in the same time (Weaver-Hightower, 2010). Over time, this growing gender imbalance in higher education has been …

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Snail Determines The Therapeutic Response To Mtor Kinase Inhibitors By Transcriptional Repression Of 4e-Bp1, Jun Wang, Qing Ye, Yanan Cao, Yubin Guo, Xiuping Huang, Wenting Mi, Side Liu, Chi Wang, Hsin-Sheng Yang, Binhua P. Zhou, B. Mark Evers, Qing-Bai She Dec 2017

Snail Determines The Therapeutic Response To Mtor Kinase Inhibitors By Transcriptional Repression Of 4e-Bp1, Jun Wang, Qing Ye, Yanan Cao, Yubin Guo, Xiuping Huang, Wenting Mi, Side Liu, Chi Wang, Hsin-Sheng Yang, Binhua P. Zhou, B. Mark Evers, Qing-Bai She

Markey Cancer Center Faculty Publications

Loss of 4E-BP1 expression has been linked to cancer progression and resistance to mTOR inhibitors, but the mechanism underlying 4E-BP1 downregulation in tumors remains unclear. Here we identify Snail as a strong transcriptional repressor of 4E-BP1. We find that 4E-BP1 expression inversely correlates with Snail level in cancer cell lines and clinical specimens. Snail binds to three E-boxes present in the human 4E-BP1 promoter to repress transcription of 4E-BP1. Ectopic expression of Snail in cancer cell lines lacking Snail profoundly represses 4E-BP1 expression, promotes cap-dependent translation in polysomes, and reduces the anti-proliferative effect of mTOR kinase inhibitors. Conversely, genetic …

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Socio-Cultural Determinants Of Physical Activity Across The Life Course: A 'Determinants Of Diet And Physical Activity' (Dedipac) Umbrella Systematic Literature Review, Lina Jaeschke, Astrid Steinbrecher, Agnes Luzak, Anna Puggina, Katina Aleksovska, Christoph Buck, Con Burns, Greet Cardon, Angela Carlin, Simon Chantal, Donatella Ciarapica, Giancarlo Condello, Tara Coppinger, Cristina Cortis, Marieke De Craemer, Sara D'Haese, Andrea Di Blasio, Sylvia Hansen, Licia Iacoviello, Johann Issartel, Pascal Izzicupo, Martina Kanning, Aileen Kennedy, Fiona Chun Man Ling, Giorgio Napolitano, Julie Anne Nazare, Camille Perchoux, Angela Polito, Walter Ricciardi, Alessandra Sannella, Wolfgang Schlicht, Rhoda Sohun Dec 2017

Socio-Cultural Determinants Of Physical Activity Across The Life Course: A 'Determinants Of Diet And Physical Activity' (Dedipac) Umbrella Systematic Literature Review, Lina Jaeschke, Astrid Steinbrecher, Agnes Luzak, Anna Puggina, Katina Aleksovska, Christoph Buck, Con Burns, Greet Cardon, Angela Carlin, Simon Chantal, Donatella Ciarapica, Giancarlo Condello, Tara Coppinger, Cristina Cortis, Marieke De Craemer, Sara D'Haese, Andrea Di Blasio, Sylvia Hansen, Licia Iacoviello, Johann Issartel, Pascal Izzicupo, Martina Kanning, Aileen Kennedy, Fiona Chun Man Ling, Giorgio Napolitano, Julie Anne Nazare, Camille Perchoux, Angela Polito, Walter Ricciardi, Alessandra Sannella, Wolfgang Schlicht, Rhoda Sohun

Publications

Objective: Regular physical activity (PA) reduces the risk of disease and premature death. Knowing factors associated with PA might help reducing the disease and economic burden caused by low activity. Studies suggest that socio-cultural factors may affect PA, but systematic overviews of findings across the life course are scarce. This umbrella systematic literature review (SLR) summarizes and evaluates available evidence on socio-cultural determinants of PA in children, adolescents, and adults. Methods: This manuscript was drafted following the recommendations of the 'Preferred Reporting Items for Systematic reviews and Meta-Analyses' (PRISMA) checklist. The MEDLINE, Web of Science, Scopus, and SPORTDiscus databases were …

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Identification Of Massoia Lactone And Its Hydroxy-Derivative From Kabatiella Caulivora, An Endophyte Of The Terrestrial Plant Alyxia Reinwardtii, Izzatul Laili, Sri Gunarso, Nashrul Wathan, Noor Erma Sugijanto, Gunawan Indrayanto Dec 2017

Identification Of Massoia Lactone And Its Hydroxy-Derivative From Kabatiella Caulivora, An Endophyte Of The Terrestrial Plant Alyxia Reinwardtii, Izzatul Laili, Sri Gunarso, Nashrul Wathan, Noor Erma Sugijanto, Gunawan Indrayanto

Makara Journal of Science

Massoia lactone (1) and its derivative, 3,5-dihydroxydecanoic acid-d-lactone (2), were identified from an ethyl acetate extract of the endophytic fungus Kabatiella caulivora, isolated from its host Alyxia reinwardtii. The compounds were identified by GC-MS. To the best of our knowledge, this is the first report of the identification of massoia lactone and its derivative from the endophytic K. caulivora fungus.

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Nutrient Accumulation In The Sediment Of Silvofishery Ponds In Semarang, Endah Dwi Hastuti, Rini Budihastuti Dec 2017

Nutrient Accumulation In The Sediment Of Silvofishery Ponds In Semarang, Endah Dwi Hastuti, Rini Budihastuti

Makara Journal of Science

Information concerning the functionality of mangrove within silvofishery ponds is needed, especially relating to the accumulation rate of organic materials and nutrients. This research studied the effect of mangrove structure on the accumulation rate of nutrients within silvifishery ponds. The research, conducted in May 2016, used canals of width 1, 2, and 3 m, with mangrove species Avicennia marina and Rhizophora mucronata, alone or in combination. Nutrients measured were nitrogen, phosphorus and organic matter, in the sediment of the treatment ponds, through soil sampling followed by laboratory analysis. The respective analysis methods used were Kjehdahl, spectrophotometry, and ashing. Data analysis …

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Activity Of Cytotoxic Flavanoids Against A P-388 Murine Leukemia Cell Line From The Stem Bark Of Aglaia Elliptica (Meliaceae), Ace Tatang Hidayat, Kindi Farabi, Desi Harneti, Rani Maharani, Nurlelasari, Unang Supratman, Yoshihito Shiono Dec 2017

Activity Of Cytotoxic Flavanoids Against A P-388 Murine Leukemia Cell Line From The Stem Bark Of Aglaia Elliptica (Meliaceae), Ace Tatang Hidayat, Kindi Farabi, Desi Harneti, Rani Maharani, Nurlelasari, Unang Supratman, Yoshihito Shiono

Makara Journal of Science

Two mixtures of flavanoid compounds (1 and 2), a mixture of catechin (1a) and epicatechin (1b), and a mixture of gallocatechin (2a) and epigallocatechin (2b), were isolated from the active fraction of the stem bark of Aglaia elliptica methanol extract. The chemical structure of the compounds was identified with spectroscopic data, including UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H COSY), and MS, and additionally compared with previously reported spectral data. All compounds were evaluated for their cytotoxic effects against P-388 murine leukemia cells. Compound 2 showed cytotoxicity against the P-388 murine leukemia cell, with an IC50 value …

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Synthetic Jet Actuator-Based Aircraft Tracking Using A Continuous Robust Nonlinear Control Strategy, N. Ramos-Pedroza, W. Mackunis, M. Reyhanoglu Dec 2017

Synthetic Jet Actuator-Based Aircraft Tracking Using A Continuous Robust Nonlinear Control Strategy, N. Ramos-Pedroza, W. Mackunis, M. Reyhanoglu

Publications

A robust nonlinear control law that achieves trajectory tracking control for unmanned aerial vehicles (UAVs) equipped with synthetic jet actuators (SJAs) is presented in this paper. A key challenge in the control design is that the dynamic characteristics of SJAs are nonlinear and contain parametric uncertainty. The challenge resulting from the uncertain SJA actuator parameters is mitigated via innovative algebraic manipulation in the tracking error system derivation along with a robust nonlinear control law employing constant SJA parameter estimates. A key contribution of the paper is a rigorous analysis of the range of SJA actuator parameter uncertainty within which asymptotic …

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Agenda For The Fifth Meeting Of The Forum On Soil Dynamics, Shamsher Prakash Dec 2017

Agenda For The Fifth Meeting Of The Forum On Soil Dynamics, Shamsher Prakash

Forum for Promotion of Soil Dynamics in India

No abstract provided.

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Mitigating Projected Impacts Of Climate Change And Building Resiliency Through Permaculture: A Community ‘Bee Inspired Gardens’ Movement In The Desert Southwest, Usa, Roslynn Brain, Jeffrey Adams, Jeremy Lynch Dec 2017

Mitigating Projected Impacts Of Climate Change And Building Resiliency Through Permaculture: A Community ‘Bee Inspired Gardens’ Movement In The Desert Southwest, Usa, Roslynn Brain, Jeffrey Adams, Jeremy Lynch

Environment and Society Faculty Publications

Permaculture, an integrative design process creating resilient and productive landscapes and communities, can serve as a useful mitigation tool for projected climate change impacts. In the United States, the desert southwest town of Moab, Utah, has employed permaculture design in a community initiative called ‘Bee Inspired Gardens.’ This initiative has harnessed social capital to create resilient landscapes demonstrating pollinator health, water conservation, and perennial food and forage systems. Bee Inspired Gardens have been designed at a University, middle school, charter school, Bureau of Land Management property, hotel, public park, environmental education non-profit, and more. Community members are now harvesting fruit …

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Identification Of Avian Influenza Genetic Resistance Gene Marker In Chickens, R Susanti, Nur Rahayu Utami, Margareta Rahayuningsih, Fidia Fibriana Dec 2017

Identification Of Avian Influenza Genetic Resistance Gene Marker In Chickens, R Susanti, Nur Rahayu Utami, Margareta Rahayuningsih, Fidia Fibriana

Makara Journal of Science

The Mx gene is a potential candidate as a genetic resistance marker to the avian influenza virus in chickens. The purpose of this study is to identify the potential of Mx gene as a marker of resistance to avian influenza viruses in various breeds of chicken. The study used an exploratory design using three common chicken breeds. The Kampong chicken, the Hy-Line Brown laying hen strain, and the White Leghorn broiler strain were collected from the local farms, and blood samples were drawn from each. The DNA of each sample was amplified by a pair of Mx gene primers (NE-F2/F …

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High Levels Of Resistance In A Culex Quinquefasciatus Population To The Insecticide Permethrin In Filariasis Endemic Areas In Central Java, Irfanul Chakim, Sayono, Rahayu Astuti Dec 2017

High Levels Of Resistance In A Culex Quinquefasciatus Population To The Insecticide Permethrin In Filariasis Endemic Areas In Central Java, Irfanul Chakim, Sayono, Rahayu Astuti

Makara Journal of Science

Resistance among Culex mosquitoes to various insecticides has been reported in many countries. However, there have been no studies of the resistance status of Culex in Indonesia. There is a need for such studies to develop a database for use in vector control management. This study aimed to investigate the insecticide resistance status of C. quenquefasciatus, which is the primary vector of filariasis, to aid the planning of a vector control management program. In the present study, Culex quinquefasciatus larvae were collected from five districts/municipalities where filariasis is endemic in Central Java. The larvae were reared to adult stage, and …

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The Abundance Of Nitrogen Fixing, Nitrifying, Denitrifying And Ammonifying Bacteria In The Soil Of Tropical Rainforests And Oil Palm Plantations In Jambi, Zulfarina, Iman Rusmana, Nisa Rachmania Mubarik, Dwi Andreas Santosa Dec 2017

The Abundance Of Nitrogen Fixing, Nitrifying, Denitrifying And Ammonifying Bacteria In The Soil Of Tropical Rainforests And Oil Palm Plantations In Jambi, Zulfarina, Iman Rusmana, Nisa Rachmania Mubarik, Dwi Andreas Santosa

Makara Journal of Science

Alterations in the use of land for oil palm plantations can change the domination and activity of soil bacteria. More specifically, alteration in soil microbial communities can directly affect soil ecosystem functioning, particularly with respect to carbon and nitrogen cycles. Nitrogen can be a limiting nutrient, and the availability of nitrogen in the soil environment becomes a major factor in controlling the production of biomass. This research project aimed at studying the abundance of nitrogen-fixing, nitrogen-oxidizing, nitrogen-reducing, and ammonifying bacteria based on their functional genes in the tropical rain forests of Taman Nasional Bukit Duabelas (TNBD) and the oil palm …

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Identification Of A Major Quantitative Trait Locus For Grain Weight In Rice Using Microsatellite Marker, Mariana Susilowati, Hajrial Aswidinnoor, Wening Enggarini, Kurniawan Rudi Trijatmiko Dec 2017

Identification Of A Major Quantitative Trait Locus For Grain Weight In Rice Using Microsatellite Marker, Mariana Susilowati, Hajrial Aswidinnoor, Wening Enggarini, Kurniawan Rudi Trijatmiko

Makara Journal of Science

Rice is one of the major staple foods in the world, especially in Asia. Improving yield potential of superior cultivars is important to meeting the demand for rice production, which is increasing due to human population increase, climate change, and degradation of agricultural resources, such as land and water. In this study, a BC3F2 population developed from an intraspecific cross between Ciherang and a new plant type line (B11143D) was used in a quantitative trait locus (QTL) analysis. Ciherang is a high yielding rice cultivar with good grain quality which has been planted in 37% of the irrigated rice area …

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Minutes Of The Fifth Meeting Of The Forum For Promotion Of Soil Dynamics In India, Shamsher Prakash Dec 2017

Minutes Of The Fifth Meeting Of The Forum For Promotion Of Soil Dynamics In India, Shamsher Prakash

Forum for Promotion of Soil Dynamics in India

No abstract provided.

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Ls301 Fluorescence-Guided Photodynamic Therapy Of Brain Cancer Using Ppix Photosensitizer, Haini Zhang Dec 2017

Ls301 Fluorescence-Guided Photodynamic Therapy Of Brain Cancer Using Ppix Photosensitizer, Haini Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Incomplete brain tumor removal always causes neurologic deficit, disease recurrence and high mortality. Protoporphyrin IX (PpIX) accumulated in glioma cells with exogenous 5-aminolevulinic acid (5-ALA) serves as contrast agent for fluorescence-guided surgery and as well as acts as a photosensitizer for photodynamic therapy (PDT). However, the accurate tumor delineation using PpIX is limited by autofluorescence and superficial penetration depth. LS301 is a tumor-targeted near-infrared (NIR) contrast agent developed in our lab which allows deeper tumor imaging and avoids autofluorescence. My project aims to investigate whether LS301 can improve PpIX mediated PDT and tumor removal surgery. We have demonstrated co-localization of …

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First Record Of Sorex Tenellus From Utah, Eric A. Rickart, Shannen L. Robson, Lois F. Alexander, Duke S. Rogers Dec 2017

First Record Of Sorex Tenellus From Utah, Eric A. Rickart, Shannen L. Robson, Lois F. Alexander, Duke S. Rogers

Western North American Naturalist

A specimen of the Inyo shrew, Sorex tenellus, was collected in piñon-juniper woodland at 2017 m elevation in Granite Creek Canyon, Deep Creek Range, Juab Co., Utah. This is the easternmost record for this species and the first record for Utah.


Un especimen de la musaraña Inyo, Sorex tenellus, fué colleccionado en el bosque de piñón y enebro a una elevación de 2017 m dentro de Granite Creek Canyon, Deep Creek Range, Juab Co., Utah. Este es el registro más oriental de esta especie y el primer registro para Utah.

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Neutrality And Outer Space, Wolff Heintschel Von Heinegg Dec 2017

Neutrality And Outer Space, Wolff Heintschel Von Heinegg

International Law Studies

This article discusses the law of neutrality as it pertains to belligerent operations in and through outer space as well as belligerent outer space operations involving the territory and national airspace of neutral States. As far as the latter is concerned, the traditional law of neutrality is fully applicable. Accordingly, international law prohibits belligerents from launching space objects from neutral territory or through neutral national airspace. While neutral States may not provide belligerents with outer space assets or the use of communications infrastructure located in their territories, they are not obliged to prevent their nationals from providing any of the …

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Virtual Reality As A Training Tool To Treat Physical Inactivity In Children, Adam W. Kiefer, David Pincus, Michael J. Richardson, Gregory D. Myer Dec 2017

Virtual Reality As A Training Tool To Treat Physical Inactivity In Children, Adam W. Kiefer, David Pincus, Michael J. Richardson, Gregory D. Myer

Psychology Faculty Articles and Research

Lack of adequate physical activity in children is an epidemic that can result in obesity and other poor health outcomes across the lifespan. Physical activity interventions focused on motor skill competence continue to be developed, but some interventions, such as neuromuscular training (NMT), may be limited in how early they can be implemented due to dependence on the child’s level of cognitive and perceptual-motor development. Early implementation of motor-rich activities that support motor skill development in children is critical for the development of healthy levels of physical activity that carry through into adulthood. Virtual reality (VR) training may be beneficial …

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Analysis On Nature Index In Asia Region: Examples Of China, India, Japan, South Korea, And Singapore, Lin Lin, Zhang Guoyou, He Shujin Dec 2017

Analysis On Nature Index In Asia Region: Examples Of China, India, Japan, South Korea, And Singapore, Lin Lin, Zhang Guoyou, He Shujin

Bulletin of Chinese Academy of Sciences (Chinese Version)

In the way of analyzing the article count, fractional count, and weighted fractional count from the nature index, taking the example of China, India, Japan, South Korea, and Singapore, we compare the ability, advantaging subjects, efficiency of the high-quality research, and the international collaboration, indicating that China has a much better high-quality research than the other Asia Pacific countries, but has a relatively lower research efficient and out-of-balance subject development. China, Japan, and Australia are the main outer collaborating countries with each other.

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Human Organs-On-A-Chip, Qin Jianhua, Zhang Min, Yu Hao, Li Zhongyu Dec 2017

Human Organs-On-A-Chip, Qin Jianhua, Zhang Min, Yu Hao, Li Zhongyu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Human organs-on-a-chip is a newly emerging and frontier technology involving with different disciplines in recent years. It refers to a biomimetic microphysiological system created on a bioengineered microfluidic device, representing the organ-level functional units. It can recapitulate the physiologically relevant structures and functions of the organs, as well as the interaction between multiple organs as in vivo, thereby offering alternative models for predicting human responses to various drugs and environmental stimulus. Organs-on-a-chip technology has wide application potentials in many fields such as life science, drug discovery, personalized medicine, food/environment monitoring and biological defense et al. The emergence of this …

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Impact Of Pivotal Announcement Event On Carbon Price In European Union Emission Trading Scheme, Jia Junjun, Xu Jinhua, Fan Ying Dec 2017

Impact Of Pivotal Announcement Event On Carbon Price In European Union Emission Trading Scheme, Jia Junjun, Xu Jinhua, Fan Ying

Bulletin of Chinese Academy of Sciences (Chinese Version)

With the worsening of global climate change, establishment of carbon trading scheme has become an important option for governments to address the issue of climate change. As newly created market, carbon market is easily subject to the shocks from institution modification, rule adjustment, and vital information announcement. The research establishes an event study method through modeling bilaterally modified dummy variables in AR-GARCH model to unveil the ex ante and ex post impact process and impact pattern of the announcement event. The study takes National Allocation Plans (NAP) announcement and Verified Emission Announcement (VEA) event in the European Union emission trading …

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Biosensors For Water Pollution Monitoring, Xia Shanhong, Bian Chao, Sun Jizhou, Xie Yong, Han Mingjie, Xiong Chenyu Dec 2017

Biosensors For Water Pollution Monitoring, Xia Shanhong, Bian Chao, Sun Jizhou, Xie Yong, Han Mingjie, Xiong Chenyu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Biosensors have many applications. Biological and chemical samples can be detected by utilizing the specific recognition between biomolecules. This paper investigates and reviews the research and development of biosensors for water environment monitoring. Biosensors with different sensing mechanisms and materials, such as enzyme, immune, DNA, tissue, microorganism biosensors, as well as their applications for detecting various water pollution parameters are described.

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Electrochemical Sensing Of Neurotransmitters With High Temporal And Spatial Resolution, Zhang Yueyue, Zuo Xiaolei, Fan Chunhai Dec 2017

Electrochemical Sensing Of Neurotransmitters With High Temporal And Spatial Resolution, Zhang Yueyue, Zuo Xiaolei, Fan Chunhai

Bulletin of Chinese Academy of Sciences (Chinese Version)

Currently, real time monitoring the release of neurotransmitters from living cells with high temporal and spatial resolution remains challenging. In recent years, quantitative analysis of neurotransmitter releasing has been achieved by developing different electrochemical monitoring techniques, and cell release patterns have been investigated. In addition, monitoring with high resolution and sensitivity can be achieved by modifying the electrode surface or regulating the electrode dimensions. The combining of different monitoring techniques can further improve the monitoring capability. This paper reviews the mechanism of electrochemical detection of neurotransmitter, the development of microelectrode and nanoelectrode for neurotransmitter detection, the coupling of electrochemical technology …

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Biosensors: 50 Years Development And Future Perspectives, Zhang Xian-En Dec 2017

Biosensors: 50 Years Development And Future Perspectives, Zhang Xian-En

Bulletin of Chinese Academy of Sciences (Chinese Version)

Biosensors are the devices made of biological elements and physical or chemical transducers for fast and specific determination of biological or related substances, of which is a typical convergence technology. Biosensors have broad application prospects in life science research, disease diagnosis and control, bioengineering process control, agriculture and food security, environmental quality monitoring, biosafety and biosecurity, etc. 50 years after its birth, biosensor technology has entered a new phase of vigorous development. The main driving forces are the introduction and implementation of the concepts of One-Health, Internet of Things, and big data. Research hot topics include wearable and portable biosensing …

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Research Progress Of Bioinspired Smell And Taste Sensors, Wang Ping, Zhuang Liujing, Qin Zhen, Zhang Bin, Gao Keqiang Dec 2017

Research Progress Of Bioinspired Smell And Taste Sensors, Wang Ping, Zhuang Liujing, Qin Zhen, Zhang Bin, Gao Keqiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The mammalian olfactory and gustatory system is recognized as the most effective chemosensing systems due to their extraordinary ability in odor and tastant detection. Detection of odors has been applied to many real applications, such as quality control of food products, safety and security, environmental monitoring, medical diagnosis and so on. Here, we focus on the principle, basic composition, employed technology and application of electronic nose/electronic tongue, molecule and cell based olfactory/gustatory biosensors. We also introduce the research progress of a novel system which we called ' in vivo bioelectronic nose and tongue'. Finally, the further trend in this area …

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Molecular Biosensors And Molecular Imaging In Cells, Wang Dianbing, Cui Zongqiang, Zhang Xian-En Dec 2017

Molecular Biosensors And Molecular Imaging In Cells, Wang Dianbing, Cui Zongqiang, Zhang Xian-En

Bulletin of Chinese Academy of Sciences (Chinese Version)

Molecular sensors are the biosensors made of macrobiomolecules. They are significant tools for real-time imaging of the molecular events in living cells and in vivo. Molecular beacons (MB), fluorescence/bioluminescence resonance energy transfer sensors (FRET/BRET) and molecular fluorescence complementation systems (BiFC, TriFC, etc.) are major types of molecular biosensors for live cell imaging applications. In this paper, the principles and characteristics of the molecular biosensors are described. The biosensors show their unique role in study of biomolecular interactions, localization, movement, and kinetics in living cells. The restrains, challenges, and future prospects of the molecular biosensors are also discussed. Because "Seeing …

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Pde8 Is Expressed In Human Airway Smooth Muscle And Selectively Regulates Camp Signaling By Β 2 Ar-Ac6, Timothy B. Johnstone, Kaitlyn H. Smith, Cynthia J. Koziol-White, Fengying Li, Austin G. Kazarian, Maia L. Corpuz, Maya Shumyachter, Frederick J. Ehlert, Bianca E. Himes, Reynold A. Pannettieri Jr., Rennolds S. Ostrom Dec 2017

Pde8 Is Expressed In Human Airway Smooth Muscle And Selectively Regulates Camp Signaling By Β 2 Ar-Ac6, Timothy B. Johnstone, Kaitlyn H. Smith, Cynthia J. Koziol-White, Fengying Li, Austin G. Kazarian, Maia L. Corpuz, Maya Shumyachter, Frederick J. Ehlert, Bianca E. Himes, Reynold A. Pannettieri Jr., Rennolds S. Ostrom

Pharmacy Faculty Articles and Research

Two cAMP signaling compartments centering around adenylyl cyclase (AC) exist in human airway smooth muscle (HASM) cells, one containing ß2AR-AC6 and another containing E prostanoid receptors (EPR)-AC2. We hypothesized that different phosphodiesterase (PDE) isozymes selectively regulate cAMP signaling in each compartment. According to RNA-seq data, 18 of 24 PDE genes were expressed in primary HASM cells derived from age- and gender-matched donors with and without asthma. PDE8A was the third most abundant of the cAMP-degrading PDE genes, after PDE4A and PDE1A. Knockdown of PDE8A using shRNA evoked 2-fold greater cAMP responses to 1 DM forskolin in the presence of IBMX. …

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Information Ethics Among Graduate Students Of The University Of Ghana, Fynn Kwamena Paapa Mr., Ernest Boakye Mr. Dec 2017

Information Ethics Among Graduate Students Of The University Of Ghana, Fynn Kwamena Paapa Mr., Ernest Boakye Mr.

Library Philosophy and Practice (e-journal)

This paper examines the extent to which graduate students of the University of Ghana are aware of information ethics and their perceptions on this important subject. The survey method was employed. As the population of 3,538 was too large to be studied, a sample size of 178 (representing 5% of graduate population) were given a questionnaire to complete. The results show that the students surveyed are adequately aware of Information Ethics and that majority of the students comply with Information Ethics. The study also found that most of the students are motivated by access to the Internet and electronic databases …

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