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Articles 631 - 660 of 62841
Full-Text Articles in Entire DC Network
Prevalence And Possible Factors Associated With Anaemia, And Vitamin B 12 And Folate Deficiencies In Women Of Reproductive Age In Pakistan: Analysis Of National-Level Secondary Survey Data, Sajid Bashir Soofi, Gul Nawaz Khan, Kamran Sadiq, Shabina Ariff, Atif Habib, Sumra Kureishy, Imtiaz Hussain, Muhammad Umer, Zamir Suhag, Arjumand Rizvi, Zulfiqar Ahmed Bhutta
Prevalence And Possible Factors Associated With Anaemia, And Vitamin B 12 And Folate Deficiencies In Women Of Reproductive Age In Pakistan: Analysis Of National-Level Secondary Survey Data, Sajid Bashir Soofi, Gul Nawaz Khan, Kamran Sadiq, Shabina Ariff, Atif Habib, Sumra Kureishy, Imtiaz Hussain, Muhammad Umer, Zamir Suhag, Arjumand Rizvi, Zulfiqar Ahmed Bhutta
Department of Paediatrics and Child Health
Objective: To determine the prevalence and possible factors associated with anaemia, and vitamin B12 and folate deficiencies in women of reproductive age (WRA) in Pakistan.
Methods: A secondary analysis was conducted on data collected through the large-scale National Nutrition Survey in Pakistan in 2011. Anaemia was defined as haemoglobin levels <12 g/dL, vitamin B12 deficiency as serum vitamin B12 levels of <203 pg/mL (150 pmol/L) and folate deficiency as serum folate levels <4 ng/mL (10 nmol/L).
Results: A total of 11751 blood samples were collected and analysed. The prevalence of anaemia, vitamin B12 deficiency and folate deficiency was 50.4%, 52.4% and 50.8%, respectively. After adjustment, the following factors were positively associated with anaemia: living in Sindh province (RR 1.07; 95%CI 1.04 to 1.09)P<0.00, food insecure with moderate hunger (RR 1.03; 95%CI 1.00 to 1.06)P=0.02, four or more pregnancies (RR 1.03; 95%CI 1.01 to 1.05)P<0.00, being underweight (RR 1.03; 95%CI 1.00 to 1.05)P=0.02, being overweight or obese (RR 0.95; 95%CI 0.93 to 0.97)P<0.00 and weekly intake of leafy green vegetables (RR 0.98; 95%CI 0.95 to 1.00)P=0.04. For vitamin B12 deficiency, a positive association was observed with rural population (RR 0.81; 95%CI 0.66 to 1.00)P=0.04, living in Khyber Pakhtunkhwa province (RR 1.25; 95%CI 1.11 to 1.43)P<0.00 and living in Azad Jammu and Kashmir (RR 1.50; 95%CI 1.08 to 2.08)P=0.01. Folate deficiency was negatively associated with daily and weekly intake of eggs (RR 0.89; 95%CI 0.81 to 0.98)P=0.02 and (RR 0.88; 95%CI 0.78 to 0.99)P=0.03.
Conclusions: In Pakistan, …0.00,>12>
Perceived Effect Of Personality Traits On Information Seeking Behaviour Of Postgraduate Students In Universities In Benue State, Nigeria, Victor Ozowa, Jane Igie Aba
Perceived Effect Of Personality Traits On Information Seeking Behaviour Of Postgraduate Students In Universities In Benue State, Nigeria, Victor Ozowa, Jane Igie Aba
Library Philosophy and Practice (e-journal)
ABSTRACT
This study investigated perceived effect of personality traits on information seeking behaviour of postgraduate students in Universities in Benue state. The study focused on information seeking behaviour and personality traits in the area of extroversion, conscientiousness, agreeableness, openness to experience and neuroticism. Six (6) research questions were raised and five hypotheses were formulated to guide the study. The study adopted survey research design. The entire population of 373 registered postgraduate students’ library users was used as sample.Research instruments was an adopted questionnaire titled “Questionnaire on the Perceived Effect of Personality Traits on Information Seeking Behaviour of Postgraduate Students in …
The Application And Usefulness Of Economic Analyses For Water Quality Management In Coastal Areas, Sheri L. Jewhurst, Kate K. Mulvaney, Marisa J. Mazzotta
The Application And Usefulness Of Economic Analyses For Water Quality Management In Coastal Areas, Sheri L. Jewhurst, Kate K. Mulvaney, Marisa J. Mazzotta
Journal of Ocean and Coastal Economics
Economic studies are increasingly sought as tools to contribute to water quality management in estuaries and coastal communities, yet little is known about how the results from existing studies have been received and utilized by the organizations who solicited them. We interviewed managers from eight organizations who solicited economic studies over the past 15 years to understand how useful the studies were to their organizations and what economic research would be most helpful for their management needs. In terms of utility for coastal managers, there are a number of limitations in the studies. These include lack of site-specific data, the …
Welcome To The Inaugural Issue Of Collaborations: A Journal Of Community-Based Research And Practice, Scotney D. Evans
Welcome To The Inaugural Issue Of Collaborations: A Journal Of Community-Based Research And Practice, Scotney D. Evans
Collaborations: A Journal of Community-Based Research and Practice
This is an introduction to the inaugural issue of Collaborations: A Journal of Community-based Research and Practice. Collaborations is a free, open access, online journal, sponsored by the University of Miami and Rutgers University. We’ve created this journal to be a home for sharing research, practice, and learning emanating from community-university collaborations.
Tomicus Piniperda (Coleoptera: Scolytidae) Reproduction And Behavior On Scotch Pine Christmas Trees Taken Indoors, Robert A. Haack, Robert K. Lawrence
Tomicus Piniperda (Coleoptera: Scolytidae) Reproduction And Behavior On Scotch Pine Christmas Trees Taken Indoors, Robert A. Haack, Robert K. Lawrence
The Great Lakes Entomologist
Tomicus piniperda, the pine shoot beetle, is an exotic insect that was first found in North America in 1992. A federal quarantine currently restricts movement of pine products, including Christmas trees, from infested to uninfested counties. We conducted a study to determine if T. piniperda would re- produce in Christmas trees that were cut and taken indoors during the Christmas season. Twelve Scotch pine, Pinus sylvestris, Christmas trees infested with overwintering T. piniperda beetles were cut in Indiana in early December 1993 and taken to Michigan. Four trees were dissected immediately, while the other 8 trees were taken …
Allegory And Ambiguity In The Films Of Majid Majidi: A Theodicy Of Meaning (Farsi), Cyrus Ali Zargar
Allegory And Ambiguity In The Films Of Majid Majidi: A Theodicy Of Meaning (Farsi), Cyrus Ali Zargar
Journal of Religion & Film
This paper explores the place of traditional metaphysics in Iranian cinema through an analysis of three films by Majid Majidi. Countering evaluations of Majidi’s films as tritely patriarchal or heavy-handedly logocentric, this paper considers images and allegories in Majidi’s films as responses to the pains of modernity. Majidi’s films, specifically, Children of Heaven, Baran, and the Color of God, draw on Sufi and Shii theologies to locate meaning in a world changed by war, modernization, economic disparity, and nationalism. The result is a sense of ambiguity that aims at both realism and transcendence.
Effects Of An Alcohol Education Program On Improving Knowledge, Attitudes And Satisfaction Of Registered Nurses Caring For Patients Undergoing Alcohol Withdrawal, Luis Medina
Seton Hall University DNP Final Projects
Managing and caring for patients who are undergoing alcohol withdrawal presents challenges for nurses in an inpatient setting. These challenges are influenced by factors such as negative attitudes, lack of knowledge and poor satisfaction. The purpose of this quality improvement initiative was to determine whether the effects of implementing an alcohol educational program would improve knowledge and satisfaction while reducing negative attitudes. This program implemented education on alcoholism, alcohol withdrawal and the Clinical Institute Withdrawal Assessment of Alcohol Scale, Revised (CIWA-Ar) monitoring tool which would be incorporated into the everyday practice of nurses caring for patients undergoing alcohol withdrawal. The …
Brief Of 40 Historians And The Fred T. Korematsu Center For Law And Equality, As Amici Curiae In Support Of Plaintiffs' Motion For Preliminary Injunction, Fred T. Korematsu Center For Law And Equality, Robert S. Chang
Brief Of 40 Historians And The Fred T. Korematsu Center For Law And Equality, As Amici Curiae In Support Of Plaintiffs' Motion For Preliminary Injunction, Fred T. Korematsu Center For Law And Equality, Robert S. Chang
Fred T. Korematsu Center for Law and Equality
No abstract provided.
Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi
Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi
Jefferson Digital Commons News
Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!
Implementation Of An Opioid Risk Assessment Tool, Stacey Cuomo
Implementation Of An Opioid Risk Assessment Tool, Stacey Cuomo
Seton Hall University DNP Final Projects
The increased prevalence of opioid use in society has led to an increase in surgical patients with a history of such use. Patients who use or are addicted to opioids have different tolerances and responses to anesthesia than non-opioid users, and will require different care than non-users both pre- and post-operatively. The means to identify this population prior to a surgical procedure is needed as a way to organize, plan and manage patient care during the perioperative period. An Opioid Risk Assessment Tool (ORAT) was used as a way to streamline the process of identifying these patients. This paper addresses …
The Effectiveness Of Nurse-Driven Early Mobility Protocol, Viktoriya Fridman
The Effectiveness Of Nurse-Driven Early Mobility Protocol, Viktoriya Fridman
Seton Hall University DNP Final Projects
Purpose: The purpose of this quality initiative is to introduce the nurse driven evidence-based practice change related to patient mobility in the hospital setting with the aim to improve nurse knowledge, attitude, and behavior on a medical-surgical unit.
Significance of Project: The proposed DNP quality project is devised from the American Academy of Nursing (AAN) Choosing Wisely campaign unique to the elements of “don’t let older adults lay in bed or only get up to a chair during their hospital stay” to achieve a practice change. A significant aspect of patient care in a hospital setting is patient …
Emma Lucy Braun's Forest Plots In Eastern North America, Robert Ricklefs
Emma Lucy Braun's Forest Plots In Eastern North America, Robert Ricklefs
Biology Department Faculty Works
No abstract provided.
The Malaria Testing And Treatment Landscape In Kenya: Results From A Nationally Representative Survey Among The Public And Private Sector In 2016., Kathryn A. O'Connell, Vamsi Vasireddy, Megan Littrell, Andria Rusk, Actwatch Group, Anne Musuva, Waqo Ejersa, Rebecca Kiptui, Dorothy Memusi, Edward Abwao
The Malaria Testing And Treatment Landscape In Kenya: Results From A Nationally Representative Survey Among The Public And Private Sector In 2016., Kathryn A. O'Connell, Vamsi Vasireddy, Megan Littrell, Andria Rusk, Actwatch Group, Anne Musuva, Waqo Ejersa, Rebecca Kiptui, Dorothy Memusi, Edward Abwao
Collected Faculty Scholarship
BACKGROUND: Since 2004, Kenya's national malaria treatment guidelines have stipulated artemisinin-based combination therapy (ACT) as first-line treatment for uncomplicated malaria, and since 2014, confirmatory diagnosis of malaria in all cases before treatment has been recommended. A number of strategies to support national guidelines have been implemented in the public and private sectors in recent years. A nationally-representative malaria outlet survey, implemented across four epidemiological zones, was conducted between June and August 2016 to provide practical evidence to inform strategies and policies in Kenya towards achieving national malaria control goals.
RESULTS: A total of 17,852 outlets were screened and 2271 …
A Framework For Linking Population Model Development With Ecological Risk Assessment Objectives, Sandy Raimondo, Matthew Etterson, Nathan Pollesch, Kristina Garber, Andrew Kanarek, Wade Lehmann, Jill Awkerman
A Framework For Linking Population Model Development With Ecological Risk Assessment Objectives, Sandy Raimondo, Matthew Etterson, Nathan Pollesch, Kristina Garber, Andrew Kanarek, Wade Lehmann, Jill Awkerman
United States Environmental Protection Agency: Publications
The value of models that link organism-level impacts to the responses of a population in ecological risk assessments (ERAs) has been demonstrated extensively over the past few decades. There is little debate about the utility of these models to translate multiple organism-level endpoints into a holistic interpretation of effect to the population; however, there continues to be a struggle for actual application of these models as a common practice in ERA. Although general frameworks for developing models for ERA have been proposed, there is limited guidance on when models should be used, in what form, and how to interpret model …
Removal Of Sulfur Dioxide From Flue Gas Using Absorbent Prepared By Water And Steam Hydration, Teong Lee Keat, Mohamed Abdul Rahman, Bhatia Subhash
Removal Of Sulfur Dioxide From Flue Gas Using Absorbent Prepared By Water And Steam Hydration, Teong Lee Keat, Mohamed Abdul Rahman, Bhatia Subhash
ASEAN Journal on Science and Technology for Development
Active absorbent for flue gas desulfurization was prepared from coal fly ash, calcium oxide (CaO) and calcium sulfate (CaSO4 ) by hydro-thermal process; steam and water hydration. The absorbents were examined and compared for its micro-structural properties. The experiments were conducted based on Design of Experiments (DOE) according to 24 factorial design. The effect of various absorbent preparation variables such as hydration period (Factor A), ratio of CaO to fly ash (Factor B), amount of calcium sulfate used (Factor C) and drying temperature (Factor D) towards the BET surface area of the absorbent were studied. The BET surface area of …
Silver Photodiffusion Into Ge-Rich Amorphous Germanium Sulfide—Neutron Reflectivity Study, Y. Sakaguchi, H. Asaoka, M. Mitkova
Silver Photodiffusion Into Ge-Rich Amorphous Germanium Sulfide—Neutron Reflectivity Study, Y. Sakaguchi, H. Asaoka, M. Mitkova
Electrical and Computer Engineering Faculty Publications and Presentations
Silver diffuses into chalcogenide films upon light exposure, and the kinetics of photodiffusion has been a subject of various investigations because of the difficulties in the in situ determination of the time-dependent Ag reaction and diffusion development in the chalcogenide layers. In this paper, we report the results of time-resolved neutron reflectivity measurement of Ag/Ge40S60/Si substrates under light exposure to clarify the kinetics of Ag photodiffusion into Ge-rich Ge chalcogenides. It reveals that Ag ions diffuse all over the Ge chalcogenide host layer once Ag dissolves into the layer without forming a metastable reaction layer unlike …
Does Government Contracting Have A Remedies Problem? A Response To Eric M. Singer, Competitive Public Contracts, Steven W. Feldman
Does Government Contracting Have A Remedies Problem? A Response To Eric M. Singer, Competitive Public Contracts, Steven W. Feldman
Nevada Law Journal Forum
In his provocative article, Competitive Public Contracts, Eric M. Singer claims that deficient contractor performance is inherent in government contracting. Singer asserts that, “fundamentally,” public purchasing has a “contract-remedies problem”—the absence of both any “credible threat” and any “effective contract remedy to deter or correct [contractor] misbehavior.” Unlike private buyers, who have plausible threats to motivate contractors to perform properly, governments are said to “often” labor under intrinsic and extrinsic limitations that undermine remedial alternatives. Consequently, Singer argues that governments (especially state and local agencies) have no “effective contract remedy” to induce improved contractor performance. Among these “ineffective” remedies, according …
The Effect Of Time, Roasting Temperature, And Grind Size On Caffeine And Chlorogenic Acid Concentrations In Cold Brew Coffee, Niny Z. Rao, Megan Fuller
The Effect Of Time, Roasting Temperature, And Grind Size On Caffeine And Chlorogenic Acid Concentrations In Cold Brew Coffee, Niny Z. Rao, Megan Fuller
College of Humanities and Sciences Faculty Papers
The extraction kinetics and equilibrium concentrations of caffeine and 3-chlorogenic acid (3-CGA) in cold brew coffee were investigated by brewing four coffee samples (dark roast/medium grind, dark roast/coarse grind, medium roast/medium grind, medium roast/coarse grind) using cold and hot methods. 3-CGA and caffeine were found at higher concentrations in cold brew coffee made with medium roast coffees, rather than dark roast. The grind size did not impact 3-CGA and caffeine concentrations of cold brew samples significantly, indicating that the rate determining step in extraction for these compounds did not depend on surface area. Caffeine concentrations in cold brew coarse grind …
The Gender Wage Gap: Causes, Consequences, And Remedies, Yaveline Aly
The Gender Wage Gap: Causes, Consequences, And Remedies, Yaveline Aly
Honors Program Theses and Projects
Women are almost half of the workforce, yet they are still getting pay less than men. They receive more college degree than men. Hispanic women and African American women get pay even less than men. For every 40 hours that Americans women work, they only get pay 80 cents for every dollar paid to men. Wage discrimination is a reality. Society needs to take a stand and fight for wages equality (NWLC.org). Although the equal pay act was implemented 50 years ago, women of every race and education level are still getting pay less than men. It only gets worse …
Identifying Significant Components Of A Sexuality Education Program For Students With Severe Disabilities, Amanda Brennen
Identifying Significant Components Of A Sexuality Education Program For Students With Severe Disabilities, Amanda Brennen
Honors Program Theses and Projects
The body of knowledge in the field of sex education that has been modified for individuals with disabilities is currently lacking. There are currently no evidence based practices for sexuality education. The programs that currently exist are either not effective for the severe population or there is no research to support its use. However, people that are considered in the population of severe special education could benefit greatly from a sexuality program that is evidence based.
The researcher conducted a study to determine the topics that are common in the literature and that are important to teachers and their with …
Application Of Back Propagation Neural Network In Predicting Palm Oil Mill Emission, Azid I.A., Yusoff A.R., Seetharamu K.N., Ahmad A.L.
Application Of Back Propagation Neural Network In Predicting Palm Oil Mill Emission, Azid I.A., Yusoff A.R., Seetharamu K.N., Ahmad A.L.
ASEAN Journal on Science and Technology for Development
The paper presents an approach to investigate and monitor the air pollution caused by the palm oil mill. A concept of dealing with the problem from its causes is used where the sources of pollution from the stack gases were examined. The main causes were from the combustion of shell fibre and of the palm oil. However, in the boiler itself, several parameters like steam load and pressure, fuel capacity and temperature also contribute to the pollution. The study uses Neural Network (NN) to simulate the process of combustion and stack gases. This neural network was trained by using the …
Use Of An Alternative Natural Weed Suppressant: Effects Of Parboiled Rice Hull Mulch On The Growth Of Container Weeds, Amy R. Fields-Taylor, Vanessa Slinger-Friedman
Use Of An Alternative Natural Weed Suppressant: Effects Of Parboiled Rice Hull Mulch On The Growth Of Container Weeds, Amy R. Fields-Taylor, Vanessa Slinger-Friedman
The Kennesaw Journal of Undergraduate Research
The Chattahoochee Nature Center (CNC) is one of the leading educational centers in Georgia about the ecology of the Chattahoochee River. Due to lack of man power, keeping down the weeds in the CNC plant nursery is one of those tasks that often gets left undone. The nursery becomes overgrown with invasive weed species. Understandably, they must sometimes resort to the use of herbicides, such as Roundup®, to keep the hundreds of native and endangered species of plants housed at CNC from being choked out by invasive weeds. This study tests the ability to suppress weed growth by use of …
The Demographics Of The Modern American Senate And How It Reflects The Modern American Voter, Caitlin A. O'Kelley, April Johnson
The Demographics Of The Modern American Senate And How It Reflects The Modern American Voter, Caitlin A. O'Kelley, April Johnson
The Kennesaw Journal of Undergraduate Research
As a body intended to accurately represent the people of the United States, the U.S. Senate is not a very diverse group. However, it is the people themselves who vote their representatives into office. In seeking to find what qualities American voters look for in a senator, senatorial longevity is an excellent gauge. Through the analysis of previous studies and literature and the gathering of original data on the senatorial longevity of the 115th Congress, independent variables such as sex, education, and children can be analyzed to determine the demographic makeup of the successful American senator; thereby also analyzing …
Prevalence And Incidence Of Health Risk Factors Among Adolescent Girls, Kylah Pollard, Mohammed Chowdhury, Sarai Bauguess
Prevalence And Incidence Of Health Risk Factors Among Adolescent Girls, Kylah Pollard, Mohammed Chowdhury, Sarai Bauguess
The Kennesaw Journal of Undergraduate Research
Heart Disease has many different risk factors, including hypertension (high blood pressure) and high cholesterol. Research has shown that hypertension can be identified as early as adolescence, and preventative measures can be instilled in this age. However, the relationship between hypertension, high cholesterol, race, and income have not been studied in detail among adolescents. The present study analyzed the effects of different health factors on blood pressure and cholesterol levels in Caucasian and African-American girls ages 9-21 years old, the prime of adolescence. The dataset was part of a larger study completed by the National Heart, Blood, and Lung Institute …
The Weekly Challenger, December 21, 2017, The Weekly Challenger, Et Al
The Weekly Challenger, December 21, 2017, The Weekly Challenger, Et Al
Weekly Challenger Newspaper Collection
The December 21, 2017, issue of The Weekly Challenger.
Visual Odometry Using Convolutional Neural Networks, Alec Graves, Steffen Lim, Thomas Fagan, Kevin Mcfall Phd.
Visual Odometry Using Convolutional Neural Networks, Alec Graves, Steffen Lim, Thomas Fagan, Kevin Mcfall Phd.
The Kennesaw Journal of Undergraduate Research
Visual odometry is the process of tracking an agent's motion over time using a visual sensor. The visual odometry problem has only been recently solved using traditional, non-machine learning techniques. Despite the success of neural networks at many related problems such as object recognition, feature detection, and optical flow, visual odometry still has not been solved with a deep learning technique. This paper attempts to implement several Convolutional Neural Networks to solve the visual odometry problem and compare slight variations in data preprocessing. The work presented is a step toward reaching a legitimate neural network solution.
Behavioral Indicators Of Poor Welfare In Shelter Dogs, Paige M. Adams, Suma Mallavarapu
Behavioral Indicators Of Poor Welfare In Shelter Dogs, Paige M. Adams, Suma Mallavarapu
The Kennesaw Journal of Undergraduate Research
We studied behavioral indicators of poor welfare in shelter dogs. Our research question was: How is the welfare of shelter dogs affected by length of stay at a shelter, age, sex, and breed. Data were collected on 18 dogs from October 2016 to March 2017 at a small private shelter in Marietta, GA. Data were collected in 15-minute sessions when the dogs were in their indoor enclosures. No significant differences were found in time spent in abnormal behaviors among dogs that were at the shelter for less than 1 month, 1-6 months, and longer than 6 months, between males and …
Are The Stock Markets “Rigged”? An Empirical Analysis Of Regulatory Change, Stephen F. Diamond, Jennifer W. Kuan
Are The Stock Markets “Rigged”? An Empirical Analysis Of Regulatory Change, Stephen F. Diamond, Jennifer W. Kuan
Faculty Publications
Volatile events in the stock market such as the 2010 Flash Crash have sparked concern that financial markets are “rigged” in favor of trading firms that use high frequency trading (“HFT”) systems. We analyze a regulatory change implemented by the SEC in 2007 by examining its effect on a key market metric, the bid-ask spread, an investor cost, and find that the regulatory shift, indeed, disadvantages investors. We link the implementation of this change to a shift in the volume of trades from a low-cost venue to a high-cost venue. We argue that this outcome is predicted by the incentives …
Higher Education And The Lasallian Mission In An Age Of Inequality, Steven Nawara, Shelley Mccallum-Ferguson, Eoin O'Connell
Higher Education And The Lasallian Mission In An Age Of Inequality, Steven Nawara, Shelley Mccallum-Ferguson, Eoin O'Connell
Political Science Department Faculty Articles
In this paper we propose that institutions like the Schools of the Christian Brothers play an important role as a counterweight to free market inequalities. First we explore the free market mechanism and draw attention to its negative externalities. Then we highlight the resemblance between these negative externalities and the context that inspired Jean Baptiste de La Salle to found the Schools of the Christian Brothers. We show how the Christian Brothers organization is inspired by ideals that are sharply distinct from those that govern a strictly capitalist system. The governing principles of the Schools of the Christian Brothers are …
Lacosamide And Levetiracetam Have No Effect On Sharp-Wave Ripple Rate, Jan Kudlacek, Jan Chvojka, Antonin Posusta, Lubica Kovacova, Seung Bong Hong, Shennan A. Weiss, Md, Phd, Kamila Volna, Petr Marusic, Jakub Otahal, Premysl Jiruska
Lacosamide And Levetiracetam Have No Effect On Sharp-Wave Ripple Rate, Jan Kudlacek, Jan Chvojka, Antonin Posusta, Lubica Kovacova, Seung Bong Hong, Shennan A. Weiss, Md, Phd, Kamila Volna, Petr Marusic, Jakub Otahal, Premysl Jiruska
Department of Neurology Faculty Papers
Pathological high-frequency oscillations are a novel marker used to improve the delineation of epileptogenic tissue and, hence, the outcome of epilepsy surgery. Their practical clinical utilization is curtailed by the inability to discriminate them from physiological oscillations due to frequency overlap. Although it is well documented that pathological HFOs are suppressed by antiepileptic drugs (AEDs), the effect of AEDs on normal HFOs is not well known. In this experimental study, we have explored whether physiological HFOs (sharp-wave ripples) of hippocampal origin respond to AED treatment. The results show that application of a single dose of levetiracetam or lacosamide does not …