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The Human Mitochondrial Chaperonin: It Takes Two Single-Rings To Tango, Adrian Sergio Enriquez

Open Access Theses & Dissertations

The human mitochondrial chaperonin is a macromolecular machine that catalyzes the proper folding and assembly of newly imported mitochondrial proteins into their biologically active state. It is composed of two proteins from the highly conserved heat shock protein family, hsp10 and hsp60, that assemble into large oligomeric complexes responsible for mediating the folding of non-native polypeptides in an ATP dependent manner. In addition to its innate role in protein folding, human mitochondrial hsp60 has been implicated in numerous moonlighting cellular activities that have been linked to diseases conditions such as cancer and neurodegeneracy. In light of its cellular importance, the …

Teacher Challenges In Implementing Cognitively Demanding Tasks In The Mathematics And Science Classrooms, Angelica Monarrez Monarrez

Open Access Theses & Dissertations

This mixed methods study examines secondary school mathematics and science teachersâ?? understanding of cognitive demand and the challenges in implementing tasks at different levels of cognitive demand. The conceptual framework for this study is grounded on the conception of cognitive demand proposed by Stein, Smith, Henningsen, and Silver (2000), which includes the following levels: memorization (level 1), procedures without connections (level 2), procedures with connections (level 3), and doing mathematics and science (level 4). The study attempts to address the following research questions: 1) To what extent are secondary mathematics and science teachers able to recognize, solve and construct tasks …

The Texas Sales Tax Rebate Program, Jose Angel Moreno

Open Access Theses & Dissertations

The sale tax rebate program has existed in states along the U.S. â?? Mexico border for over 60 years and, in Texas, it has been the subject of much debate regarding both its legitimacy and its efficacy in stimulating real retail sales particularly in border cities. No empirical research exists, though, that provides insight into the statistical relationships between the Texas retail sector and total certificates issued by Private Customs Brokers (PCBs) in border cities. This study fills this research gap by creating a model that tests the statistical significance of real retail sales on total certificates issued in Texas. …

The Prohibitin Protein Complex Promotes Mitochondrial Stabilization And Cell Survival In Hematologic Malignancies, Elisa Robles Escajeda

Open Access Theses & Dissertations

Lymphocyte proliferation and differentiation is coordinated with high precision in healthy humans and is vital to maintaining a normal immune system. Imbalance of these events can result in the development of autoimmune diseases, immunodeficiencies and hematopoietic malignancies. These pathologies, specifically leukemia and lymphoma have a high incidence of relapse and mortality due to limited treatment options. Therefore, there is a critical need to characterize the signal transduction pathways and understand molecular hallmarks that mediate T cell activation in order to develop new strategies for diagnosis and treatments of these diseases.

Prohibitins (PHB1 and PHB2) have been proposed to play important …

Schrödinger Theory Of Electrons In Electromagnetic Fields: New Perspectives, Viraht Sahni, Xiao-Yin Pan

Publications and Research

The Schrödinger theory of electrons in an external electromagnetic field is described from the new perspective of the individual electron. The perspective is arrived at via the time-dependent "Quantal Newtonian" law (or differential virial theorem). (The time-independent law, a special case, provides a similar description of stationary-state theory). These laws are in terms of "classical" fields whose sources are quantal expectations of Hermitian operators taken with respect to the wave function. The laws reveal the following physics: (a) in addition to the external field, each electron experiences an internal field whose components are representative of a specific property of the …

Critical Agrarian Studies In Theory And Practice, Marc Edelman, Wendy Wolford

Publications and Research

Abstract: In this introductory article we argue for renewed attention to life and labor on and of the land—or what we call the field of Critical Agrarian Studies. Empirically rich and theoretically rigorous studies of humanity’s relationship to “soil” remain essential not just for historical analysis but for understanding urgent contemporary crises, including widespread food insecurity, climate change, the proliferation of environmental refugees, growing corporate power and threats to biodiversity. The article introduces an innovative and varied collection of works in Critical Agrarian Studies and also examines the intellectual and political history of this broader field.

Resumen: En este artículo …

Emancipatory Rural Politics: Confronting Authoritarian Populism, Ian Scooner, Marc Edelman, Saturnino M. Borras Jr., Ruth Hall, Wendy Wolford, Ben White

Publications and Research

A new political moment is underway. Although there are significant differences in how this is constituted in different places, one manifestation of the new moment is the rise of distinct forms of authoritarian populism. In this opening paper of the JPS Forum series on ‘Authoritarian Populism and the Rural World’, we explore the relationship between these new forms of politics and rural areas around the world. We ask how rural transformations have contributed to deepening regressive national politics, and how rural areas shape and are shaped by these politics. We propose a global agenda for research, debate and action, which …

Burnout Symptoms: Depressive Manifestations Under Psychosocial Labels?, Bianchi Renzo, Irvin Sam Schonfeld, Eric Laurent

Publications and Research

It can be concluded that burnout symptoms represent depressive symptoms under nonmedical labels. Our analysis supports the view that burnout is synonymous with depression and constitutes a roadblock to transdisciplinary communication.

Fisher V. Ebay, District Of Connecticut

Historical and Topical Legal Documents

No abstract provided.

Carson V. Cernx, California Superior Court

Historical and Topical Legal Documents

No abstract provided.

Couponcabin V. Savings.Com, Northern District Of Indiana

Historical and Topical Legal Documents

Denying judgment on the pleadings

Hanna V. Amazon.Com, Middle District Of North Carolina

Historical and Topical Legal Documents

No abstract provided.

In Re Cain (Gonzalez V. Twitter), Southern District Of New York

Historical and Topical Legal Documents

No abstract provided.

Bartolucci V. 1-800 Contacts, District Court Of The District Of Columbia

Historical and Topical Legal Documents

No abstract provided.

Palomino V. Facebook, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Quirky, Inc. V. Facebook, Inc., Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Pennie V. Twitter, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Hassell V. Yelp, California Supreme Court

Historical and Topical Legal Documents

RESPONDENTS’ ANSWERING BRIEF ON THE MERITS

Yahoo V. National Union Fire Insurance Company, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Vigil V. Take-Two Interactive, Southern District Of New York

Historical and Topical Legal Documents

No abstract provided.

Dehen V. Doe, Southern District Of California

Historical and Topical Legal Documents

No abstract provided.

Sojourner Center V. Backpage, District Of Arizona

Historical and Topical Legal Documents

No abstract provided.

Florida Abolitionist V. Backpage, Middle District Of Florida

Historical and Topical Legal Documents

No abstract provided.

E-Ventures Worldwide V. Google, Middle District Of Florida

Historical and Topical Legal Documents

No abstract provided.

Shetty V. Alphabet, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Mansoor V. Doe, Central District Of California

Historical and Topical Legal Documents

No abstract provided.

Chegg V. Hydrick, District Of Utah

Historical and Topical Legal Documents

No abstract provided.

Oneida Group V Steelite International, Eastern District Of New York

Historical and Topical Legal Documents

No abstract provided.

Rivera V. Google, Northern District Of Illinois

Historical and Topical Legal Documents

No abstract provided.

Dropbox V. Thru, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.