Digital Commons Network^™

Judicial Activism - The Violation Of An Oath, Edward J. Melvin, C.M.

The Catholic Lawyer

No abstract provided.

Gsu View, 2017-09-18, Office Of Marketing And Communications

GSU View

No abstract provided.

The Tiger Vol. 112 Issue 3 2017-09-18, Clemson University

Tiger Newspapers 2017

No abstract provided.

Scalable Technologies For Process Intensification In The Continuous Biomanufacturing Factories Of The Future, Gerben Zijlstra

Integrated Continuous Biomanufacturing III

Continuous and intensified bioprocessing is attracting much attention from biopharmaceutical companies seeking to maximize the efficiency of their manufacturing assets. Continuous and intensified bioprocessing promises smaller facilities, reduced scale-up risk, more consistent product quality and higher throughputs. However, there are still many (technical) challenges for practical implementation of intensified and continuous bioprocesses. In the upstream processing, tools for high throughput intensified and continuous cell culture development are limited, furthermore at 2000 L scale many single use bioreactors may not be suitable to support the high cell densities required for intensified processing. Furthermore, current cell retention systems are expensive, suffer from …

Continuous Gas Processing Without Bubbles Using Thin Liquid Film Bioreactors Containing Biocomposite Biocatalysts, Michael C. Flickinger, Christopher Duran, Adam Wallace, Mark J. Schulte, Orlin D. Velev, Nilay Chakraborty, Michael Guarnieri, Kamelia Boodhoo

Integrated Continuous Biomanufacturing III

Continuous microbial gas processing without bubbles is possible with thin liquid film, plug flow bioreactors. We have demonstrated that power input can be minimized by using a falling liquid film operating under laminar wavy flow conditions (Re <200) in contact with highly concentrated living, non-growing microbes stabilized in a porous biocomposite biocatalyst. This composite materials approach to continuous gas processing can dramatically increase mass transfer rates >100 fold compared to bubble aeration, decrease process volume, significantly decrease gas-liquid mass transfer energy input, decrease water use, and increase secreted product concentration. We have shown that this approach can also increase microbial specific activity for some organisms compared to microbes suspended in liquid media. Paper-based biocomposite biocatalysts provide a rough hydrophilic surface resulting in uniform ~300 μm thick falling liquid films. …

Ada News - 09/18/2017, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Honors Student Association Continues Big Sweep Tradition, Sthefany Flores

GWU-Today

The Gardner-Webb Honors Student Association (HSA) participated in its annual Big Sweep retreat September 8-10.

Up And Down Scale Considerations For The Continuous Production Of Glycooptimized Biopharmaceuticals, Steffen Kreye, Rainer Stahn

Integrated Continuous Biomanufacturing III

Product quality especially with respect to glycosylation is a critical product attribute which can have an immense influence on the activity of glycoproteins and should be closely monitored during process development and manufacturing. GlycoExpressTM cells have been developed in this context to provide human host cell lines with robust glycosylation machineries. This work will address challenges in two case studies for up and down scaling of production processes with focus on product quality and continuous processing. In a first section, data of a process transfer from a 200 L stainless steel to a 1000 L single-use bioreactor for a continuous …

Bioprocess Intensification And Optimisation Using Macroscopic Predictive Models Of Cell Culture Processes, Bassem Ben Yahia, Boris Fessler, Gwendal Gränicher, An-Vy Tran, Mareike Harmsen, Elmar Heinzle

Integrated Continuous Biomanufacturing III

Chinese Ovary Hamster (CHO) are an indispensable tool for biotechnological production of biologics which is a multi-million business. Recently, the pharmaceutical industry is increasingly focusing in the use of perfusion mode. Nevertheless, the optimal perfusion rate during biopharmaceutical perfusion production is dependent on cell metabolism which can be characterized by mathematical models. This study provides insights into the predictive capacities of systematic and simple cell modeling approaches of metabolism, growth and production of monoclonal antibodies (mAb) [1] to optimized medium composition and perfusion rate during CHO perfusion culture. We applied the metabolic steady state concept and used a segmented linear …

A First Linkage Map And Downy Mildew Resistance Qtl Discovery For Sweet Basil (Ocimum Basilicum) Facilitated By Double Digestion Restriction Site Associated Dna Sequencing (Ddradseq), Robert M. Pyne, Josh Honig, Jennifer Vaiciunas, Adolfina R. Koroch, Christian Wyenandt, Stacy Bonos, James Simon

Publications and Research

Limited understanding of sweet basil (Ocimum basilicum L.) genetics and genome structure has reduced efficiency of breeding strategies. This is evidenced by the rapid, worldwide dissemination of basil downy mildew (Peronospora belbahrii) in the absence of resistant cultivars. In an effort to improve available genetic resources, expressed sequence tag simple sequence repeat (EST-SSR) and single nucleotide polymorphism (SNP) markers were developed and used to genotype the MRI x SB22 F2 mapping population, which segregates for response to downy mildew. SNP markers were generated from genomic sequences derived from double digestion restriction site associated DNA sequencing (ddRADseq). Disomic segregation was observed …

Science Funding Tops $3m, Dave Larsen

College of Arts and Sciences Newsroom

The National Science Foundation has awarded eight grants totaling more than $2.3 million to University of Dayton College of Arts and Sciences faculty during the last 12 months - supporting science, technology, engineering and mathematics research for the common good. Combined with two previous, active grants, the College's current NSF funding total exceeds $3 million.

The Statesman, V. 61, I. 04, Stony Brook University

Stony Brook Statesman-Sucolian

v. 61, i. 04;

Deep Learning Methods For Protein Torsion Angle Prediction, Haiou Li, Jie Hou, Badri Adhikari, Qiang Lyu, Jianlin Cheng

Computer Science Faculty Works

Background: Deep learning is one of the most powerful machine learning methods that has achieved the state-of-the-art performance in many domains. Since deep learning was introduced to the field of bioinformatics in 2012, it has achieved success in a number of areas such as protein residue-residue contact prediction, secondary structure prediction, and fold recognition. In this work, we developed deep learning methods to improve the prediction of torsion (dihedral) angles of proteins. Results: We design four different deep learning architectures to predict protein torsion angles. The architectures including deep neural network (DNN) and deep restricted Boltzmann machine (DRBN), deep recurrent …

Current, September 18, 2017, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

The Indiana Statesman, September 18, 2017, Indiana State University

Student Newspaper

State honored with multiple national rankings; Bat myths busted as festival patrons push conservation efforts; Pi Kappa Alpha holds annual fundraiser; ISU driven to increase student success

Columbia Chroncle (09/18/2017), Columbia College Chicago

Columbia Chronicle

Student newspaper from September 18, 2017 entitled The Columbia Chronicle. This issue is 40 pages and is listed as Volume 53, Issue 3. Cover story: "DACA debacle: A Dreamer's nightmare". Editor-in-Chief: Zoe Eitel

Review Of Seagrassnet Monitoring Photographs In Great Bay, New Hampshire, Usa 2007 - 2014, Frederick T. Short

PREP Reports & Publications

SeagrassNet is a global monitoring program begun in 2001 and designed to scientifically detect and document seagrass habitat change (Short et al. 2006a, 2014). Monitoring of eelgrass (Zostera marina L.) in the Great Bay Estuary using SeagrassNet was conducted in Portsmouth Harbor between 2001 and 2009 (Short et al 2006b, Rivers and Short 2007), and is ongoing in Great Bay itself, from 2007 (Short 2009) to the present. In this report, July quadrat photos taken along the three Great Bay SeagrassNet transects from 2007 – 2014 are presented and discussed. They provide useful documentation of field percent cover measurements of …

Estate Of Jeffrey H. Ware V. Hospital Of The University Of

2017 Decisions

USDC for the Eastern District of Pennsylvania

Faculty Senate Executive Committee Agenda, September 18, 2017, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• EPC Annual Report
• Honors Program Report
• Parking Committee Annual Report
• Libraries Advisory Council Annual Report
  
  
  

Can Squirrel Monkeys Learn An Abna Grammar? A Re-Evaluation Of Ravignani Et Al. (2013), Stefano Ghirlanda

Publications and Research

Ravignani et al. (2013) habituated squirrel monkeys to sound sequences conforming to an ABnA grammar (nD1;2;3), then tested them for their reactions to novel gram- matical and non-grammatical sequences. Although they conclude that the monkeys ``consistently recognized and generalized the sequence ABnA,'' I remark that this conclusion is not robust. The statistical significance of results depends on specific choices of data analysis, namely dichotomization of the response variable and omission of specific data points. Additionally, there is little evidence of generalization to novel patterns (n D 4;5), which is important to conclude that the monkeys recognized the ABnA grammar beyond …

Current, September 18, 2017, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Daily Eastern News: September 18, 2017, Eastern Illinois University

September

No abstract provided.

Efficacy Of Neutral And Negatively Charged Liposome-Loaded Gentamicin On Planktonic Bacteria And Biofilm Communities, Moayad Alhariri, Majad A. Majrashi, Ali H. Bahkali, Faisal S. Almajed, Ali Azghani, Mohammed A. Khiyami, Essam J. Alyamani, Sameera M. Aljohani, Majed A. Halwani

Biology Faculty Publications and Presentations

We investigated the efficacy of liposomal gentamicin formulations of different surface charges against Pseudomonas aeruginosa and Klebsiella oxytoca. The liposomal gentamicin formulations were prepared by the dehydration-rehydration method, and their sizes and zeta potential were measured. Gentamicin encapsulation efficiency inside the liposomal formulations was determined by microbiologic assay, and stability of the formulations in biologic fluid was evaluated for a period of 48h. The minimum inhibitory concentration and the minimum bactericidal concentration were determined, and the in vitro time kill studies of the free form of gentamicin and liposomal gentamicin formulations were performed. The activities of liposomal gentamicin in preventing …

Prevalence Of Kaposi’S Sarcoma-Associated Herpesvirus In Uygur And Han Populations From The Urumqi And Kashgar Regions Of Xinjiang, China, Jun Zheng, Yang Yang, Meng Cui, Zhan-Jun Shu, Li-Li Han, Zhen-Qiu Liu, Charles Wood, Tiejun Zhang, Yan Zeng

Nebraska Center for Virology: Faculty Publications

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the infectious etiologic agent associated with Kaposi’s sarcoma (KS), primary effusion lymphoma, and multicentric Castleman disease. It has been shown that high KSHV prevalence and high incidence of both classic KS and AIDSassociated KS are found mostly among people of Uygur ethnicity in Xinjiang, while people of Han ethnicity in Xinjiang have a higher KSHV seroprevalence than those of other Han populations in mainland China. However, it is still unclear why there is such geographical and population variation in KSHV distribution in China. In this work, we focused on the populations in the Kashgar region …

Bio Major, Refugee Runs For Manchester Alderman, Kassidy Taylor

UNH Today Archive

No abstract provided.

The Rider (2017-09-18), Jesus Sanchez

The Rider Archives

Vol.3 No.4

Week Of September 18, 2017, New York Medical College

InTouch

• Building the Touro College of Dental Medicine Clinical Training Facility − From the Inside Out
• Noted Physiotherapist Shares His Views on Cultural Competence
• Founder of Achilles International Gives Inspirational Talk

College Of Education News, College Of Education, Georgia Southern University

College of Education: News & Publications (2003-2023)

• COE welcomes new faculty and staff for fall 2017

Medical School Watercooler Newsletter - September 17, 2017, Lindsey Lyle

Watercooler Newsletter

This is the September 17, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Department of Pediatrics Improves Patient Access, Focuses on Quality Improvement

Dr. Elizabeth Minto Guest Speaker to Annual MS Leadership Class

USA College of Medicine Welcomes Coordinator of Student Affairs

Winners of Clyde G. ‘Sid’ Huggins Medical Student Research Awards Announced

USA Mourns Loss of Dr. Paul Dyken

Application Of Single Pass Tff To Enable Intensified And Continuous Biological Manufacturing, Herb Lutz

Integrated Continuous Biomanufacturing III

No abstract provided.