Digital Commons Network^™

Korf Named Uab Medicine's Chief Genomics Officer, Kendra Carter

Browse All News

No abstract provided.

Ecosystem Drought Response Timescales From Thermal Emission Versus Shortwave Remote Sensing, Erika Andujar, Nir Krakauer, Chuixiang Yi, Felix Kogan

Publications and Research

Remote sensing is used for monitoring the impacts of meteorological drought on ecosystems, but few large-scale comparisons of the response timescale to drought of different vegetation remote sensing products are available. We correlated vegetation health products derived frompolar-orbiting radiometer observations with a meteorological drought indicator available at different aggregation timescales, the Standardized Precipitation Evapotranspiration Index (SPEI), to evaluate responses averaged globally and over latitude and biome.The remote sensing products are Vegetation Condition Index (VCI), which uses normalized difference vegetation index (NDVI) to identify plant stress, Temperature Condition Index (TCI), based on thermal emission as a measure of surface temperature, and …

Introduction, Mitchell Kooh, Mynt Marsellus

Laurier Undergraduate Journal of the Arts

No abstract provided.

Not Just Biology: Socio-Cultural Perspectives Of The Female Orgasm, Sarah Best

Laurier Undergraduate Journal of the Arts

No abstract provided.

From The Provost 2017-10-25, Karen Carey

From the Provost

No abstract provided.

Whalesong 2017-10-25, N/A N/A

Whalesong

No abstract provided.

Intelligibility And Normativity In The Study Of Religion, Bharat Ranganathan

Religion Faculty Publications

In his essay “The Devil in Mr. Jones,” J. Z. Smith issues a call. If religionists do not, he writes, “persist in the quest for intelligibility, there can be no human sciences, let alone, any place for the study of religion within them.” How should Smith’s call be construed? In other words, what constitutes the “quest for intelligibility”? And what (if anything) differentiates the religionist’s quest for intelligibility from that of other humanistic scholars? Taking as my starting point Smith’s call, I will mount a constructive proposal. On my proposal, religionists should conceive their task as twofold. First, religionists should …

Volume 113 Issue 8, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Modifiable And Non-Modifiable Factors Related To The Macular Pigment Optical Density (Mpod) In A Population Of College-Aged Adults, Genesis Gisselle Guerra Gaitan

LSU Master's Theses

Age-related macular degeneration (AMD) is one of the leading causes of blindness among the elderly worldwide. Retinal problems, specifically in the macula, hold potential for development of AMD. Macular pigment optical density (MPOD) gives a measure of the thickness of the macula and therefore health of the macula. Some of the populations at risk for development of AMD include being white, female, and having light eye color. Factors related to the development of the disease have been divided into modifiable and non-modifiable; non-modifiable include a genetic predisposition. Control of modifiable factors, including body mass index (BMI) and diet [dietary intake …

President, University Of New Hampshire, The Search, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Inhibition Of Cholesterol Biosynthesis Through Rnf145-Dependent Ubiquitination Of Scap, Li Zhang, Prashant Rajbhandari, Christina Priest, Jaspreet Sandhu, Xiaohui Wu, Ryan E. Temel, Antonio Castrillo, Thomas Q. De Aguiar Vallim, Tamer Sallam, Peter Tontonoz

Saha Cardiovascular Research Center Faculty Publications

Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs. Here, we report that RNF145, a previously uncharacterized ER membrane ubiquitin ligase, participates in crosstalk between these critical signaling pathways. RNF145 expression is induced in response to LXR activation and high-cholesterol diet feeding. Transduction of RNF145 into mouse liver inhibits the expression of genes involved in cholesterol biosynthesis and reduces plasma cholesterol levels. Conversely, acute suppression of RNF145 via shRNA-mediated knockdown, or chronic inactivation of RNF145 by genetic deletion, potentiates the expression of cholesterol biosynthetic genes and increases cholesterol levels both in liver and plasma. Mechanistic studies show …

Optimization Of Overhead Irrigation In Relation To Irrigation Water Use Efficiency In The Louisiana Nursery Industry, Mark A. Wilson

LSU Master's Theses

Irrigation efficiency is an essential component of nursery production in the United States. To increase productivity of Louisiana growers, a series of studies were conducted to evaluate current nursery water practices. The objectives were to determine current irrigation practices; evaluate actual water usage; and compare nursery media for water utilization. A mailed survey determined that the majority of growers used can yard production (63%), overhead irrigation (79%), had no irrigation manager (82%) and did not collect/reuse water(61%); 50% do not test/calibrate their irrigation system. Based on this information, five nurseries using overhead irrigation were selected to determine water application and …

Isolation, Detection, And Prevention Of Foodborne Bacteria In Irrigation Water And Dairy Food, Mohammed Saleemallah Alhejaili

LSU Doctoral Dissertations

Foodborne microorganisms can be beneficial to humans or cause disease. Salmonella is one of the most causative foodborne disease outbreaks in the U.S.A. Salmonella has been detected in surface water used in irrigation, and can survive for weeks to years in water. The purpose of the study was to detect low levels of Salmonella spp. by comparing surfactant modified zeolite (SMZ) filtration and Activated Carbon (AC) filtration with the Environmental Protection Agency (EPA) method 1200. Also, to determine the generic E.coli counts and if there was a direct correlation of Salmonella to generic E. coli in irrigation water. The EPA …

Shrubs Facilitate Recruitment Of Caragana Stenophylla Pojark: Microhabitat Amelioration And Protection Against Herbivory, Li-Na Xie, Hong-Yu Guo, Zhe Liu, Christopher A. Gabler, Wei-Zhong Chen, Song Gu, Cheng-Cang Ma

School of Earth, Environmental, & Marine Sciences Faculty Publications

Key message

Mature Caragana stenophylla shrubs facilitated intraspecific sapling establishment by two mechanisms: microhabitat amelioration and protection against herbivory. Facilitation was mediated by climate, grazing, and sapling age.

Context

Pre-existing shrubs could facilitate sapling establishment of woody plants; however, how these facilitation vary across abiotic and biotic stress gradients and the underlying mechanisms remain unclear.

Aims

The aim of this study is understanding the facilitation of shrub on sapling establishment and how the two underlying mechanisms, microhabitat amelioration and protection against herbivory, vary across climatic aridity gradients, grazing gradients, and sapling age.

Methods

We conducted field sowing experiments to examine …

Spatial And Temporal Variation In Precipitation In Togo, Koffi Djaman, Vivek Sharma, Daran Rudnick, Komlan Koudahe, Suat Irkmak, Kokou Adambounou Amouzou, Jean Mianikpo Sogbedji

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Precipitation is one of the important variables in hydrological cycle and has important application in both irrigated and rainfed agricultural crop production. Better understanding of spatio-temporal variability of precipitation across Togo is important and useful for water users and most agricultural activities. Thus, the objective this study was to analyze the spatial and temporal variation in monthly and annual precipitation across Togo for the period of 1961-2001. Monthly precipitation data was provided by the national direction of meteorology. The performed analysis revealed a decline in annual total precipitation across almost all agro-ecological zones in Togo with the Maritime Region revealed …

Multiple Hypotheses Explain Variation In Extra-Pair Paternity At Different Levels In A Single Bird Family, Lyanne Brouwer, Martijn Van De Pol, Nataly Hidalgo Aranzamendi, Glen Bain, Daniel T. Baldassarre, Lesley C. Brooker, Michael G. Brooker, Diane Diane Colombelli-Négrel, Erik Enbody, Kurt Gielow, Michelle L. Hall, Allison E. Johnson, Jordan Karubian, Sjouke A. Kingma, Sonia Kleindorfer, Marina Louter, Raoul A. Mulder, Anne Peters, Stephen Pruett-Jones, Keith A. Tarvin, Derrick J. Thrasher, Claire W. Varian-Ramos, Michael S. Webster, Andrew Cockburn

School of Biological Sciences: Faculty Publications

Extra-pair paternity (EPP), where offspring are sired by a male other than the social male, varies enormously both within and among species. Trying to explain this variation has proved difficult because the majority of the interspecific variation is phylogenetically based. Ideally, variation in EPP should be investigated in closely related species, but clades with sufficient variation are rare. We present a comprehensive multifactorial test to explain variation in EPP among individuals in 20 populations of nine species over 89 years from a single bird family (Maluridae). Females had higher EPP in the presence of more helpers, more neighbors or …

The Opioid Crisis., Jennifer Stephens Do

Department of Medicine

No abstract provided.

The E3 Ubiquitin Ligase Scffbxl14 Complex Stimulates Neuronal Differentiation By Targeting The Notch Signaling Factor Hes1 For Proteolysis, Fangfang Chen, Chunxiao Zhang, Haonan Wu, Yue Ma, Xiaomin Luo, Xinqi Gong, Fan Jiang, Yaoting Gui, Hui Zhang, Fei Lu

Physics & Astronomy Faculty Research

Molecular oscillators are important cellular regulators of, for example, circadian clocks, oscillations of immune regulators, and short-period (ultradian) rhythms during embryonic development. The Notch signaling factor HES1 (hairy and enhancer of split 1) is a well-known repressor of proneural genes, and HES1 ultradian oscillation is essential for keeping cells in an efficiently proliferating progenitor state. HES1 oscillation is driven by both transcriptional self-repression and ubiquitin-dependent proteolysis. However, the E3 ubiquitin ligase targeting HES1 for proteolysis remains unclear. Based on siRNA-mediated gene silencing screening, co-immunoprecipitation, and ubiquitination assays, we discovered that the E3 ubiquitin ligase SCFFBXL14 complex regulates HES1 ubiquitination and …

Curated Collection For Educators: Five Key Papers About The Flipped Classroom Methodology., Andrew King, Megan Boysen-Osborn, Robert Cooney, Jennifer Mitzman, Asit Misra, Jennifer Williams, Tina Dulani, Michael Gottlieb

Medical Education Articles

The flipped classroom (FC) pedagogy is becoming increasingly popular in medical education due to its appeal to the millennial learner and potential benefits in knowledge acquisition. Despite its popularity and effectiveness, the FC educational method is not without challenges. In this article, we identify and summarize several key papers relevant to medical educators interested in exploring the FC teaching methodology. The authors identified an extensive list of papers relevant to FC pedagogy via online discussions within the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator. This list was augmented by an open call on Twitter (utilizing the #meded, #FOAMed, and …

Multi-Class Computational Evolution: Development, Benchmark Comparison, And Application To Rna-Seq Biomarker Discovery, Nathaniel Mark Crabtree

Theses and Dissertations

A computational evolution system (CES) is a knowledge-discovery engine that constructs and evolves classifiers with a small number of features to identify subtle, synergistic relationships among features and to discriminate groups in high-dimensional data analysis. CESs have previously been designed to only analyze binary datasets. In this work, the CES method has been expanded to accommodate multi-class data. The multi-class CES was compared to three common classification and feature selection methods: random forest, random k-nearest neighbor, and support vector machines. The four classifiers were evaluated on three real RNA sequencing datasets. Performance was evaluated via cross validation to assess classification …

Responsive Nanogel Probe For Ratiometric Fluorescent Sensing Of Ph And Strain In Hydrogels, Mingning Zhu, Dongdong Lu, Shanglin Wu, Qing Lian, Wenkai Wang, Amir H. Milani, Zhengxing Cui, Nam T. Nguyen, Mu Chen, L. Andrew Lyon, Daman J. Adlam, Anthony J. Freemont, Judith A. Hoyland, Brian R. Saunders

Engineering Faculty Articles and Research

In this study a new pH-responsive nanogel probe containing a complementary nonradiative resonance energy transfer (NRET) fluorophore pair is investigated and its ability to act as a versatile probe of network-related changes in three hydrogels demonstrated. Fluorescent sensing using NRET is a powerful method for studying relationships between Angstrom length-scale structure and macroscopic properties of soft matter. Unfortunately, inclusion of NRET fluorophores into such materials requires material-specific chemistry. Here, low concentrations of preformed nanogel probes were included into hydrogel hosts. Ratiometric photoluminescence (PL) data for the gels labeled with the nanogel probes enabled pH-triggered swelling and deswelling to be studied …

Family Presence During Trauma Resuscitation: An Eastern Association For The Surgery Of Trauma Practice Management Guideline, Mae Ann Pasquale Phd, Msn, Rn

Patient Care Services / Nursing

No abstract provided.

Real Boys Don't Do Language And Literacy--Or Do They?, Christen M. Pearson

MITESOL Journal: An Online Publication of MITESOL

Over the past several decades, there has been a decline in boys’ achievement, along with documentation of increasing struggles in language (both first and second) and literacy acquisition (Carr & Pauwels, 2006). To address this problem, gender differences have been looked at through the lens of socially and culturally constructed identity (Kindlon & Thompson, 2000; Pollack, 1998); however, emerging neurolinguistic research supports biological determinism, with evidence of strong biological (sex) differences in brain structure and function that impact language and learning (Bonomo, 2010; Gurian, 1996; Sax, 2005). This paper first provides an overview of current brain-based research on sex differences, …

Green Is Good: How Green Bonds Cultivated Into Wall Street’S Environmental Paradox, Luke Trompeter

Sustainable Development Law & Policy

When the European Investment Bank issued the first green bond in 2007, few imagined this debt instrument would attract mainstream investors. Designed to finance projects ranging from climate change prevention to clean transportation development, green bonds were geared for socially responsible investors concerned with our planet’s sustainability. However, by 2015, green bonds were issued by major corporations like Apple and municipalities like New York City at a record $40 billion. Major players on Wall Street have taken notice and look to cash in on the rapidly growing green bond market. With this new influx of investment and the bonds’ tax-exempt …

Never For-Gatt: What Recent Tbt Decisions Reveal About The Appellate Body’S Analysis Of Environmental Regulation Under The Wto Agreements, Ravi Soopramanien

Sustainable Development Law & Policy

Few environmentalists have positive things to say on the impact of the World Trade Organization (WTO) on the environment. WTO legal obligations are frequently cited as the most significant impediment to a range of environmental initiatives, including notably meaningful international coordination to combat climate change, particularly through carbon tax initiatives, and imposition of electronic waste disposal export bans. In this vein, adverse findings of WTO dispute panels on environmental conservation measures tend to attract the ire of international civil society. The tensions between liberal trade and environmental protection can be traced back to the days of the General Agreement on …

Payments In Lieu Of Taxes: The Philadelphia Experience, George S. Forde, Jr., Christopher E. Cummings

The Catholic Lawyer

No abstract provided.

10-24-2017 Swosu Biology Students To Present Yellowstone Findings, Southwestern Oklahoma State University

THE BARK ARCHIVE 2017

Eleven biology students at Southwestern Oklahoma State University will present information on Wednesday, November 1, generated from an August trip to Yellowstone National Park.

Ufm1 Founder Mutation In The Roma Population Causes Recessive Variant Of H-Abc., Eline M C Hamilton, Enrico Bertini, Luba Kalaydjieva, Bharti Morar, Dana Dojčáková, Adeline Vanderver, Recessive H-Abc Research Group.

Neurology Faculty Publications

OBJECTIVE: To identify the gene defect in patients with hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) who are negative for TUBB4A mutations.

METHODS: We performed homozygosity mapping and whole exome sequencing (WES) to detect the disease-causing variant. We used a Taqman assay for population screening. We developed a luciferase reporter construct to investigate the effect of the promoter mutation on expression.

RESULTS: Sixteen patients from 14 families from different countries fulfilling the MRI criteria for H-ABC exhibited a similar, severe clinical phenotype, including lack of development and a severe epileptic encephalopathy. The majority of patients had a …

Carroll Is Guest On Wath 970 Talk Show, Oct. 26, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Sun Glint Critical Angle Oil Detection, Shaojie Sun

C-IMAGE data

This dataset includes two MODIS L1B images and the generated sun glint reflectance (LGN) data after atmospheric correction. LGN was also modeled for the two images according to the sun/view geometry, oil and water fresnel reflection. This dataset introduced atmospheric correction and different oil fresnel reflection with water in the calculation of sun glint reflectance from MODIS imagery. By doing this, the calculated sun glint reflectance results are more accurate and the original concept of sun glint critical angle is refined.