Digital Commons Network^™

Improving Scientific Literacy Through Reading Strategies: An Action Research Study, Myra L. Finneran

Theses and Dissertations

The purpose of this quantitative action research study is to examine a Scientific Reading Intervention Model (SRIM) with students enrolled in Honors Chemistry at a private high school in South Carolina. Students were given a pre-test prior to the intervention. The research took place over a six-week period in the spring of 2017. A teacher-participant worked with the researcher-participant to implement the intervention that consisted of three reading activities—pre-reading, during-reading, and post-reading. These three activities were designed to enable the low-level science readers to better comprehend their chemistry texts by activating prior knowledge with an anticipation guide, identifying key concepts …

Effectiveness Of Community-Based Eibi Treatment: A Longitudinal Analysis Of Adaptive Behavior And Language Outcomes, John Kuntz

Theses and Dissertations

Autism spectrum disorders (ASDs) are a group of lifelong, neurodevelopmental disorders characterized by deficits in social interaction, communication, relationship development and by the presence of repetitive or stereotypical behaviors including restricted interests. Continued advances in understanding treatment outcomes and broadening access to effective treatment is critical to improving the quality of life of children with autism and their families and minimizing the cost associated with care. The overall aim of this study is to assess the effectiveness of a community-based implementation of an Early Intensive Behavioral Intervention (EIBI) treatment program through a large-sample, longitudinal secondary analysis of administrative data. Additionally, …

Statistical Mechanics Of Lipid-Liquid Crystal Systems: From Fundamentals To Sensing Applications, Donya Ohadi Kabir Maghsudlu

Theses and Dissertations

Understanding the thermodynamics of small systems has a well-established history. The non-intuitive behavior of the intensive properties of small systems comprised of less than a few hundred particles has important implications in many areas of engineering and materials science. Nevertheless, many open questions about the thermophysical properties of systems not in the thermodynamic limit remain unanswered. In the first part of this work, we explore the consequences of the coupling of two small subsystems that together make up a larger isolated system through the use of statistical mechanics and molecular dynamics simulations of Lennard-Jones particles in two dimensions. The results …

Effects Of A Mindfulness Based Intervention On Diurnal Cortisol In Cancer Survivors, Susannah Small

Theses and Dissertations

Background. There are approximately 15.5 million individuals alive today in the U.S. with a personal history of cancer. For this large and growing population, ill effects associated with cancer diagnosis and treatment include both physical and psychosocial symptoms adversely affecting quality of life. One low-risk alternative to conventional pharmaceutical use in treating these symptoms is mindfulness practice. Research on self-reported measures provides strong evidence that this type of intervention improves quality of life for cancer survivors, but evidence of impact on objective measures is limited. Cortisol, the body’s primary stress hormone, is one relatively easy to measure indicator that …

Assessing The Relationship Between Periodontal Disease And Subsequent Inflammatory Responses And Headache Disorders, Bryn E. Davis

Theses and Dissertations

Headaches are the sixth leading cause of disability worldwide, and the third leading cause of disability amongst those aged 50 and older. Several headache disorders, including migraines, have been associated with nitric oxide production. It is widely accepted that the pain associated with headache disorders is due to the ability of nitric oxide to function as a vasodilator. While nitric oxide is a known vasodilator and has been linked to headache disorder, it is also produced in response to bacterial infections. Periodontal disease is the result of long term bacterial infections occurring in the gum line and nitric oxide is …

Comparison Of Atypical Bacteriophages That Infect Caulobacter Crescentus, Doreen Nguyen

Theses and Dissertations

Several Caulobacter bacterial genomes have been recently sequenced, and all of the genomes contained one or more clusters of genes with phage origins. This observation indicates that bacteriophages contribute to the Caulobacter gene pool, so in order to understand bacteria genomes we will need to understand phage genomes as well. As part of understanding the phage genomes, we want to isolate novel bacteriophages and study their genomics. This study resulted in the isolation of 12 new phages, including four that differ from the well-studied CbKlike phages. Two of these novel phages are Podoviruses with icosahedral heads and small tails, and …

A Possible Mechanism For Leptin’S Role In Lung Function Independent Of Body Mass Index: Investigating Leptin’S Genotype, Dna, Methylation, And Serum Protein Levels, Mitra Yousefi

Theses and Dissertations

Background: Leptin, initially believed to simply be a satiety hormone responsible for obesity, is now recognized as a pleiotropic cytokine that is involved in many biological processes; including the body’s host inflammatory response. Clinically, leptin may affect lung function although research in this area is limited. It is also known that the leptin receptor is necessary for the activation of the leptin protein, making it an important protein to consider. Furthermore, single nucleotide polymorphisms (SNPs) and DNA methylations of the leptin and leptin receptor genes (LEP and LEPR respectively) may provide important insight on the relationship that leptin has …

Wind Driven Shelf Circulation: Effects Of Shoreline Orientation, Bathymetry, And Surface Cooling, Xiaodong Wu

Theses and Dissertations

The dynamic region extending from the inner- to outer-shelf is the nearshore region where an accurate understanding of the development of cross-shore flows is important as they control the exchange of constituents (e.g., pollutants, larvae, heat and biota) between the coastline and the open ocean. These flows are driven by a variety of forces, including wind and buoyancy. The wind forcing relevant to shelf circulation broadly falls within the synoptic scale of storm events, consisting of frontal systems (cold and warm fronts) and tropical storms. The buoyancy on the shelf is characterized by a vertical stratification or a pronounced cross-shore …

Environmental Relationships And Predator-Prey Interactions Within The Snapper-Grouper Complex In The Southeastern U.S. Atlantic – Implications For Fisheries Management, Dawn M. Glasgow

Theses and Dissertations

Stock assessments indicate many valuable fish species are declining, or are considered overfished and/or are undergoing overfishing. Fisheries scientists and managers in the southeastern U.S. typically have utilized a single-species approach, and relied on catch per unit effort data derived from fishery-independent surveys to determine indices of abundance for economically important reef fish. However, catchability for these surveys vary for many reasons including environmental and predator-prey relationships. This research was developed to elucidate environmental influences on reef fish assemblages and distribution of reef-associated marine predators, and examine predator-prey dynamics that may influence relative abundance of large predators based on chevron …

Molecular Evolution Of Major Epidermal Structure Genes And An Integrative Transcriptome Analysis Of Chicken Epidermal Embryogenesis, Weier Bao

Theses and Dissertations

Αlpha (α) and beta (β) keratins are the major structural proteins found in vertebrate epidermis and the β-keratins are only found in reptiles and birds. With the recent published 48 avian genomes, we searched and studied the molecular evolution of these gene families. We discovered that the expansion and contraction of different α- and β- keratins among the 48 phylogenetically diverse birds supports the importance of their role in the evolution of the feathers and the adaptation of birds to different ecological niches. Using a customized 44K microarray, we also performed transcriptome analysis on different epidermal regions (scutate scale, dorsal …

The Role Of Inflammation In Atherosclerosis, Fatma Saaoud

Theses and Dissertations

Atherosclerosis is both a chronic inflammatory disease and lipid deposition disorder characterized by accumulation of lipids, fibrous tissue, and inflammatory cells in the arterial wall. Thus, investigating the role of inflammation and the immune system in the progression of atherosclerosis may help in the development of novel therapeutics for atherosclerotic disease. Current atherosclerosis therapy is aimed at lipid targets and focused primarily on reducing plasma cholesterol levels. Clinical and experimental data support the critical role of inflammation in atherosclerosis and suggest that reducing inflammation even without affecting lipid levels may reduce the event rate of cardiovascular disease. Yet, no pure …

Marine Phosphorus Biogeochemistry Ecological Insights From Analytical Chemistry, Douglas W. Bell

Theses and Dissertations

The supply of phosphorus (P) directly impacts the growth and speciation of marine microbes (i.e., phytoplankton, bacteria, Archaea). In turn, microbial communities shape the magnitude and rate of marine biogeochemical cycles, ultimately affecting global climate and food production. This dynamic reflects the continuum of temporal and spatial scales at which the marine P cycle operates. However, linking multiple scales of cycling remains a consistent challenge. The primary objective of my dissertation was to gain insight into marine P biogeochemistry, by means of analytical chemistry, at the molecular and environmental scales of cycling. The first component of my research was to …

Growth And Characterization Of Anisotropic Gase Semiconductor For Radiation Detection And Thz Applications, Haseeb Nazir

Theses and Dissertations

Anisotropic wide-bandgap gallium selenide (GaSe) crystals were grown using high purity (7N) Ga and zone refined (ZR) Se precursor materials. The crystal growth was performed using a modified vertical Bridgman method (VBM) with a slow crystallization from the melt and with a pre-determined temperature profile. The structure, surface morphology, and the composition of the grown crystals were characterized using x-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive analysis by x-rays (EDAX), respectively. Optical absorption and transmission properties were characterized and optical bandgap was determined. Electrical resistivity has been determined using current-voltage (I V) measurements using van der Pauw …

Mercury Bioaccumulation In Three Popular Subsistence And Recreational Estuarine Fishes From Southeastern U.S.A., Taylor Cannon

Theses and Dissertations

A rising concern in recent years has occurred over the presence of methylmercury in seafood, particularly fishes, and its impact on human health. However, fish also provide many health benefits, including improved cardiovascular health and neurodevelopment. Because fishes are the main source of methylmercury exposure to humans, and are such an integral part of the human diet, understanding the risks versus the benefits of fish consumption is imperative in allowing the public to make healthy, educated choices. One way that state and federal governments attempt to do this is through issuing fish consumption advisories. Unfortunately, these advisories do not always …

Emergence Of Stranger Fear In Preschoolers With Fragile X Syndrome And Idiopathic Autism Spectrum Disorder, Jessica Scherr

Theses and Dissertations

This study investigated multiple behavioral indicators of social fear and their relationship to symptoms of autism in preschool boys with atypical and normative development using a stranger approach design. Participants consisted of 101 male preschoolers that were categorized into four groups: boys with fragile X syndrome (FXS; N= 29), FXS with elevated autism symptoms (fxASD; N = 25), idiopathic autism spectrum disorder (iASD; N = 11), and typically developing boys (TD; N = 36). Results indicated specific behavioral responses to a stranger differentiated preschoolers with more severe symptoms of autism (e.g. fxASD and iASD groups) from those with low autism …

Supercritical Carbon Dioxide Treatment Of Natural Biomaterials For Tissue Engineering Applications, Dominic M. Casali

Theses and Dissertations

The number of people requiring an organ transplant in the United States has increased considerably over the past 25 years, but the number of organ donations has stagnated; over 8,000 people now die annually while awaiting a transplant or become too sick to receive one. Tissue engineering (TE), the design and production of artificial tissues and organs in vitro, has been proposed to alleviate this problem. Though synthetic polymers offer tunable mechanical and biochemical properties, natural biomaterials have recently garnered attention in TE for their high degree of biocompatibility and ability to direct cell proliferation and constructive tissue remodeling. Yet …

African American End-Stage Renal Disease And Medication Adherence: What Are The Effects Of Everyday Racism?, Tamara Estes Savage

Theses and Dissertations

This dissertation explored the racial medication adherence disparity in end-stage renal disease (ESRD) patients. Prior research suggests that there are poor rates of medication adherence in the African American ESRD population. However, the reasons for this racial inequity are not understood. This dissertation explored the impact of everyday racism in the healthcare system in general and dialysis centers in particular on medication adherence. To gain an understanding of the possible contribution of everyday racism to medication nonadherence, Critical Race Theory (CRT) was used as the theoretical foundation of the study.

A total of 46 African American ESRD patients participated in …

Causes Of Satisfaction And Disatisfaction For Diversity Resident Librarians – A Mixed Methods Study Using Herzberg’S Motivation-Hygiene Theory, Jason Kelly Alston

Theses and Dissertations

Diversity residency librarian programs are post-MLIS programs aimed at providing recently graduated professionals with real work experience, with the expressed goal of recruiting and retaining a more-diverse workforce in professional librarianship.

This mixed-method study is one of the first empirical studies examining diversity residencies, which – at the time of this writing – have existed for more than 30 years. The study identifies concerns raised in the mostly anecdotal literature about diversity residencies, and 102 individuals identified as current or former diversity resident librarians participated in the quantitative portion of the study. In the quantitative portion of this study, there …

Three Studies Of Service-Learning As An Approach To Movement Integration In Elementary Classrooms, Robert D. Michael, Jr.

Theses and Dissertations

This dissertation consists of three studies that examine service-learning (SL) as an approach to incorporating movement integration (MI) in elementary classrooms as part of a comprehensive school physical activity program (CSPAP). All three studies attempt to advance the knowledge base about using partnership approaches to supporting schoolbased physical activity promotion.

The purpose of study one was to examine the perceptions of preservice classroom teachers (PCTs), classroom teachers (CTs), and course instructors who participated in a constructivist-guided university course with a focus on MI and a SL component. Focus groups with 172 PCTs and individual interviews with 7 CTs and 4 …

Applications Of Multimedia Resources Developed As Part Of The Virtual Cell Animation Collection In Undergraduate Introductory Biology, Eric Edward Goff

Theses and Dissertations

Calls for reform in undergraduate STEM education have arisen from an increased need for well-trained biology graduates in the future scientific workforce. To address this need, many institutions have focused on a pedagogical restructuring of instructional practices to promote deeper conceptual understanding of core biological concepts. This study investigates the implementation of multimedia resources as a possible reliable supplement to undergraduate introductory biology and aims to provide empirical evidence on the instructional best practices of their use. As a central part of this study, we focus on one specific multimedia package, the Virtual Cell Animation Collection, due to its developmental …

Contesting The Generic Refugee: Siv Identity, Community, And Agency During Resettlement, Benjamin J. Sylvester

Theses and Dissertations

This thesis examines the complexity of identity and community formation by Special Immigrant Visa (SIV) holders during resettlement in Columbia, South Carolina. It explores the ways in which identities coalesce around various themes, such as religion, gender, and military service, how these identities serve to create, expand, and claim membership in communities, and how SIVs exercise agency throughout these processes. Through semi-structured interviews with 9 SIVs in Columbia, SC, this qualitative study highlights the unique, highly individualized ways in which a select group of refugees experience resettlement, how they negotiate their placement within socio-economic hierarchies, and exercise agency to obtain …

Adoptees’ Experiences With Direct-To-Consumer Genetic Testing: Emotions, Satisfaction, And Motivating Factors, Anna Childers

Theses and Dissertations

Public awareness of the role of genetics in disease continues to expand along with the use of direct-to-consumer genetic testing (DTC-GT). One subset of customers taking advantage of the growing DTC-GT market is adoptees. Prior research has shown that adoptees appear to be more motivated than non-adoptees to learn about their genetic disease risk but have similar responses to health-related information acquired through DTC-GT. In this exploratory qualitative study, fourteen adoptees were asked about their motivations for pursuing DTC-GT; satisfaction with results; emotions throughout the process; and interest in meeting with a genetic counselor. Motivations for pursuing DTCGT fell into …

The Effects Of A Summer Reading Program On Reading Achievement And Reading Motivation, Marcia Seawright

Theses and Dissertations

Research shows that children who read books often, both in and out of school, are likely to develop better reading skills than children who have fewer opportunities to read. (Allington, 2012). While many school districts are successfully implementing various opportunities to support students’ reading development during the academic year, problems arise when students are away from school during the summer months. Studies also show that students who read below grade level at the end of third grade are six times more likely to eventually leave school without a high school diploma (National Research Council, 1998). The purpose of this combined …

Structural And Functional Studies Of Proteins From The Agricultural Pests Tetranychus Urticae And Aspergillus Fumigatus, Caleb Schlachter

Theses and Dissertations

Agricultural pests are a worldwide problem and cause billions of dollars in crop loss. In the United States alone, an estimated $40 billion USD is lost per year due to insecticide resistance [1]. Studied here are proteins (potentially new pesticide targets) from the agricultural pests Tetranychus urticae and Aspergillus fumigatus. T. urticae, or twospotted spidermite, is a polyphagous pest, and three proteins from this pest, a cyanase, a glutathione S-transferase and an intradiol ring-cleavage dioxygenase are described [2]. Cyanase is involved in the conversion of bicarbonate and cyanate, a toxic self-defense metabolite produced by plants, into ammonia and carbon dioxide. …

Mismatch Tolerance During Homologous Recombination In Mammalian Cells, Shen Li

Theses and Dissertations

Homologous recombination (HR) serves critical roles in DNA repair to maintain genome stability, and the malfunction of HR contributes to carcinogenesis and cancer development. Current research focuses on the regulation against deleterious recombination between imperfectly matching sequences, which has been documented in certain myeloid leukemias, hereditary nonpolyposis colorectal cancers and other genetic diseases. Homology dependency of recombination was examined in cultured thymidine kinase-deficient mouse fibroblasts. Cells have chromosomal integration of DNA constructs harboring a herpes tk gene (the “recipient”) and a closely linked truncated “donor” tk sequence. The recipient was rendered non-functional by insertion of the recognition site for endonuclease …

Far-Field Optical Microscopy Based On Stimulated Emission Depletion, Yunxia Wang

Theses and Dissertations

Conventional lens-based (far-field) fluorescence microscopy is a widely used imaging technique with spatial resolution up to 150–350 nm. However, this technology cannot discern very small structural features, because the spatial resolution is limited by diffraction to about half of the wavelength of light (λ/2，λ is the wavelength of light). Hence, most of the developments in microscopy aim at improving resolution. In the past decades, stimulated emission depletion (STED) microscopy has been developed to bypass the diffraction limit for the application in biological imaging with resolution approaching the nanoscale. The basic principle of STED microscopy is to employ a doughnut-shape laser …

Odor And Power In The Americas: Olfactory Consciousness From Columbus To Emancipation, Andrew Kettler

Theses and Dissertations

This dissertation analyzes discourses concerning odor within the Atlantic World from approximately 1492 until 1838. Numerous historians and philosophers have described how the Reformation’s emphasis on texts and an increased concentration on visual science during the Enlightenment influenced Western Europeans to heighten the importance of the eye to the detriment of the lower sense of smell. This dissertation begins by thinking about materialist contours of this olfactory decline through a linguistic analysis of sulfur within seventeenth century England. It then proceeds to examine how in the early Americas such a repudiation of the sense of smell did not occur. The …

Mast Cells And Lipid Cross-Talk In Skin Inflammation, Piper Alexandra Wedman

Theses and Dissertations

Atopic dermatitis (AD) is an inflammatory skin disease whose pathogenic mechanisms remain unclear. Using a validated human AD-like mouse model, we observed that skin remodeling started at a pre-symptomatic stage of AD that included cellular infiltration of the hypodermis, accompanied with activated/degranulated mast cells (MC). Local MC activation was quantified using a novel method of computer-assisted image analysis we developed and reported. Using a variation of this method, we defined morphometric parameters allowing for quantitation rather than scoring of cellular infiltration. Cell recruitment correlated with MC activation, chemokine production and increased levels of sphingolipid sphingosine-1-phosphate (S1P), produced by sphingosine kinase-1 …

From Rice Fields To Duck Marshes: Sport Hunters And Environmental Change On The South Carolina Coast, 1890–1950, Matthew Allen Lockhart

Theses and Dissertations

In part because some historians are ethically opposed to their avocation, sport hunters of the Gilded Age and Progressive Era are an understudied group. As environmental actors, they have been virtually ignored. Based on the biological traits of their quarry, one particular subset of sportsmen, waterfowl hunters, were especially disposed to manipulating the environment in which they hunted. Their efforts to attract migratory waterfowl to privately owned wetlands through habitat management, which started nearly a half-century before federal engineers and biologists undertook similar work on the national wildlife refuges in the 1930s, were pioneering. By the midpoint of the twentieth …

Elsewhere, Then, Tracie Renée Dawson

Theses and Dissertations

Elsewhere, Then is a cross-generational road novel that traces the sociopolitical and personal narrative of a family through a musician making her way from Savannah to San Francisco. Traditional road narratives have long depicted the lone female traveller as being subject to violence when stepping outside the domestic sphere, which echoes history's larger and pervasive trend of denying women agency through silence and subjugation—in life, as in stories. The novel interrogates how (and by whom) narratives are created, embellished, changed, and/or discarded through the narrator's temporal and spatial journey. A guiding force behind the novel is William H. Whyte's idea …