Digital Commons Network^™

Socio-Cultural Determinants Of Physical Activity Across The Life Course: A 'Determinants Of Diet And Physical Activity' (Dedipac) Umbrella Systematic Literature Review, Lina Jaeschke, Astrid Steinbrecher, Agnes Luzak, Anna Puggina, Katina Aleksovska, Christoph Buck, Con Burns, Greet Cardon, Angela Carlin, Simon Chantal, Donatella Ciarapica, Giancarlo Condello, Tara Coppinger, Cristina Cortis, Marieke De Craemer, Sara D'Haese, Andrea Di Blasio, Sylvia Hansen, Licia Iacoviello, Johann Issartel, Pascal Izzicupo, Martina Kanning, Aileen Kennedy, Fiona Chun Man Ling, Giorgio Napolitano, Julie Anne Nazare, Camille Perchoux, Angela Polito, Walter Ricciardi, Alessandra Sannella, Wolfgang Schlicht, Rhoda Sohun

Publications

Objective: Regular physical activity (PA) reduces the risk of disease and premature death. Knowing factors associated with PA might help reducing the disease and economic burden caused by low activity. Studies suggest that socio-cultural factors may affect PA, but systematic overviews of findings across the life course are scarce. This umbrella systematic literature review (SLR) summarizes and evaluates available evidence on socio-cultural determinants of PA in children, adolescents, and adults. Methods: This manuscript was drafted following the recommendations of the 'Preferred Reporting Items for Systematic reviews and Meta-Analyses' (PRISMA) checklist. The MEDLINE, Web of Science, Scopus, and SPORTDiscus databases were …

Potential Anticancer Effect Of Prostratin Through Sik3 Inhibition, Dalal Alotaibi, Suneetha Amara, Terrance L. Johnson, Venkataswarup Tiriveedhi

Biology Faculty Research

Prostratin, a phorbol ester natural plant compound, has been demonstrated to exert an anti‑retroviral effect through activation of latent cluster of differentiation (CD)4+T lymphocytes and inhibition of viral entry into the cell through downregulation of chemokine receptor type 4 (CXCR4) expression. However, the potential effect of prostratin on cancer is yet to be defined. As CXCR4 is well known to induce cancer migration, it was hypothesized that prostratin induces an anti‑cancer effect through inhibition of CXCR4 expression. The authors previously demonstrated that high stimulating conditions (sub‑minimal IL‑17, 0.1 ng/ml, synergized with high salt, Δ0.05 M NaCl) promote breast cancer cell …

High Levels Of Resistance In A Culex Quinquefasciatus Population To The Insecticide Permethrin In Filariasis Endemic Areas In Central Java, Irfanul Chakim, Sayono, Rahayu Astuti

Makara Journal of Science

Resistance among Culex mosquitoes to various insecticides has been reported in many countries. However, there have been no studies of the resistance status of Culex in Indonesia. There is a need for such studies to develop a database for use in vector control management. This study aimed to investigate the insecticide resistance status of C. quenquefasciatus, which is the primary vector of filariasis, to aid the planning of a vector control management program. In the present study, Culex quinquefasciatus larvae were collected from five districts/municipalities where filariasis is endemic in Central Java. The larvae were reared to adult stage, and …

Nutrient Accumulation In The Sediment Of Silvofishery Ponds In Semarang, Endah Dwi Hastuti, Rini Budihastuti

Makara Journal of Science

Information concerning the functionality of mangrove within silvofishery ponds is needed, especially relating to the accumulation rate of organic materials and nutrients. This research studied the effect of mangrove structure on the accumulation rate of nutrients within silvifishery ponds. The research, conducted in May 2016, used canals of width 1, 2, and 3 m, with mangrove species Avicennia marina and Rhizophora mucronata, alone or in combination. Nutrients measured were nitrogen, phosphorus and organic matter, in the sediment of the treatment ponds, through soil sampling followed by laboratory analysis. The respective analysis methods used were Kjehdahl, spectrophotometry, and ashing. Data analysis …

Identification Of Massoia Lactone And Its Hydroxy-Derivative From Kabatiella Caulivora, An Endophyte Of The Terrestrial Plant Alyxia Reinwardtii, Izzatul Laili, Sri Gunarso, Nashrul Wathan, Noor Erma Sugijanto, Gunawan Indrayanto

Makara Journal of Science

Massoia lactone (1) and its derivative, 3,5-dihydroxydecanoic acid-d-lactone (2), were identified from an ethyl acetate extract of the endophytic fungus Kabatiella caulivora, isolated from its host Alyxia reinwardtii. The compounds were identified by GC-MS. To the best of our knowledge, this is the first report of the identification of massoia lactone and its derivative from the endophytic K. caulivora fungus.

Identification Of Avian Influenza Genetic Resistance Gene Marker In Chickens, R Susanti, Nur Rahayu Utami, Margareta Rahayuningsih, Fidia Fibriana

Makara Journal of Science

The Mx gene is a potential candidate as a genetic resistance marker to the avian influenza virus in chickens. The purpose of this study is to identify the potential of Mx gene as a marker of resistance to avian influenza viruses in various breeds of chicken. The study used an exploratory design using three common chicken breeds. The Kampong chicken, the Hy-Line Brown laying hen strain, and the White Leghorn broiler strain were collected from the local farms, and blood samples were drawn from each. The DNA of each sample was amplified by a pair of Mx gene primers (NE-F2/F …

Activity Of Cytotoxic Flavanoids Against A P-388 Murine Leukemia Cell Line From The Stem Bark Of Aglaia Elliptica (Meliaceae), Ace Tatang Hidayat, Kindi Farabi, Desi Harneti, Rani Maharani, Nurlelasari, Unang Supratman, Yoshihito Shiono

Makara Journal of Science

Two mixtures of flavanoid compounds (1 and 2), a mixture of catechin (1a) and epicatechin (1b), and a mixture of gallocatechin (2a) and epigallocatechin (2b), were isolated from the active fraction of the stem bark of Aglaia elliptica methanol extract. The chemical structure of the compounds was identified with spectroscopic data, including UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H COSY), and MS, and additionally compared with previously reported spectral data. All compounds were evaluated for their cytotoxic effects against P-388 murine leukemia cells. Compound 2 showed cytotoxicity against the P-388 murine leukemia cell, with an IC50 value …

Holy Cross Magazine, Vol. 52, No. 1, Winter 2018, College Of The Holy Cross

Holy Cross Magazine

Syllabus: Introduction to Neuroscience
with Alo Basu, associate professor of psychology
By Meredith Fidrocki

The 2017 Sanctae Crucis Awards
In September 2017, five alumni were awarded the highest non-degree accolade the College bestows on its graduates.

Ten Years in Montserrat
The first-year program extends the Holy Cross invitation to challenge on day one
By Christopher Amenta ’06

Finding Their Role in the World: How Holy Cross Alumni Approach Careers in Medicine
Four alumni examine the lasting influence of a Jesuit, liberal arts background on their path after graduation, through medical school and beyond.
By Dave Greenslit

How Do Holy Cross …

Validation Of The Multilayered Gender Identity Questionnaires, Philip Eiseman

Dissertations

Gender identity shapes the ways transgender adults experience themselves and relate to the world around them. Although research and theory suggest that gender identity is a multidimensional construct, most measures of gender identity have viewed gender as primarily a unitary construct tied to the gender binary. The aim of this study was to develop and validate the Multilayered Gender Identity Questionnaires (MGIQ), a set of measures of gender identity, in a sample of transgender adults. Qualitative data collected through focus groups with transgender adults (N = 7) helped refine and develop these measures. A series of analyses involving a …

Pde8 Is Expressed In Human Airway Smooth Muscle And Selectively Regulates Camp Signaling By Β 2 Ar-Ac6, Timothy B. Johnstone, Kaitlyn H. Smith, Cynthia J. Koziol-White, Fengying Li, Austin G. Kazarian, Maia L. Corpuz, Maya Shumyachter, Frederick J. Ehlert, Bianca E. Himes, Reynold A. Pannettieri Jr., Rennolds S. Ostrom

Pharmacy Faculty Articles and Research

Two cAMP signaling compartments centering around adenylyl cyclase (AC) exist in human airway smooth muscle (HASM) cells, one containing ß2AR-AC6 and another containing E prostanoid receptors (EPR)-AC2. We hypothesized that different phosphodiesterase (PDE) isozymes selectively regulate cAMP signaling in each compartment. According to RNA-seq data, 18 of 24 PDE genes were expressed in primary HASM cells derived from age- and gender-matched donors with and without asthma. PDE8A was the third most abundant of the cAMP-degrading PDE genes, after PDE4A and PDE1A. Knockdown of PDE8A using shRNA evoked 2-fold greater cAMP responses to 1 DM forskolin in the presence of IBMX. …

A Duplex Endpoint Pcr Assay For Rapid Detection And Differentiation Of Leptospira Strains, D. Benacer, S.N. Mohd Zain, J.W. Lewis, M.K.N.M. Khalid, Kwai Lin Thong

Research Publications (2016 to 2020)

INTRODUCTION: This study aimed to develop a duplex endpoint PCR assay for rapid detection and differentiation of Leptospira strains. METHODS: Primers were designed to target the rrs (LG1/LG2) and ligB (LP1/LP2) genes to confirm the presence of the Leptospira genus and the pathogenic species, respectively. RESULTS: The assay showed 100% specificity against 17 Leptospira strains with a limit of detection of 23.1pg/µl of leptospiral DNA and sensitivity of 103 leptospires/ml in both spiked urine and water. CONCLUSIONS: Our duplex endpoint PCR assay is suitable for rapid early detection of Leptospira with high sensitivity and specificity.

No Beginning And No End, Ryan Arthur Florey

Theses

This thesis describes the realization of my art, created with the intention to project into a plastic medium the story of an ancient artifact, a weather-beaten stone, or a plant responding to stress in its environment. It describes the evolution of my inspiration and thought over the course of my graduate career, as well as, the various ancient cultures, artifacts, and traditions of making that I have found to be rooted in similar inspiration, and which have helped to guide the progression of my works.

Complete Mitochondrial Genomes Of Three Neotropical Sleeper Gobies: Eleotris Amblyopsis, E. Picta And Hemieleotris Latifasciata (Gobiiformes: Eleotridae), Fernando Alda, Alexandria J. Adams, W. Owen Mcmillan, Prosanta Chakrabarty

Faculty Publications

© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. We report the first complete mitochondrial genomes of three species of eleotrid fishes from the Pacific and Atlantic watersheds of Panama: Eleotris amblyopsis, E. picta, and Hemieleotris latifasciata. The three species have similar mitochondrial genomes with identical gene order; however, there are differences in the length of control region, 16S rRNA, and in seven of the tRNAs. In addition, ATP8 is one codon shorter in E. picta than in E. amblyopsis or H. latifasciata. We infer a phylogeny for Gobiiformes based on all mitochondrial protein-coding …

Illegal Wildlife Hunting And Trade In Southern Belize: An Assessment Of Impacts And Drivers, Blakely Rice

Capstone Collection

The use of wildlife as a resource is a common practice in all countries around the world, however, illegal activities are contributing to various environmental and social altercations amongst the involved communities and individuals, both directly and indirectly. This has led to the generalized global narrative on illegal wildlife hunting and trade as a “good vs. bad” convention. Although legal frameworks are in place to manage hunting and trade sustainably, governments and organizations often find themselves struggling to protect wildlife from illegal hunters, often facing dangerous situations thus the establishment of militarized conservation units. To date, most of the focus …

The Impact Of Copyright Exceptions For Researchers On Scholarly Output, Michael Palmedo

Joint PIJIP/TLS Research Paper Series

High prices restrict access to academic journals and books that scholars rely upon to author new research. One possible solution is the expansion of copyright exceptions allowing unauthorized access to copyrighted works for researchers. I test the link between copyright exceptions for health and science researchers and their publishing output at the country-subject level. I find that scientists residing in countries that implement more robust research exceptions publish more papers and books in subsequent years. This relationship between copyright exceptions and publishing is stronger in lower-income countries, and stronger where there is stricter copyright protection of existing works.

Possible Breakdown Of Dopamine Receptor Synergism In A Mouse Model Of Huntington's Disease, Samantha F. Kennedy

LSU New Orleans Theses and Dissertations

The model of basal ganglia function proposed by Albin, Young and Penney (1989) describes two anatomically independent motor pathways, the direct and indirect. However, under normal conditions striatal dopamine (DA) is required for the expression of motor behavior, and DAergic control of the two pathways (via D1 and D2 receptors, respectively) is dependent on co-activation. We tested for a possible breakdown of D1/D2 synergism using transgenic R6/1 mice bearing the human huntingtin allele (Htt). Motor stereotypy, observed prior to the onset of HD-related symptoms, was rated on a 5-point scale following activation of: A) D1 receptors alone, B) D2 receptors …

Wing Shape Variation In The Mimetic Butterfly Papilio Dardanus (Papilionidae) And Its Unpalatable Nymphalid Models, Miles Hegedus

LSU New Orleans Theses and Dissertations

Papilio dardanus displays female-limited polymorphic mimicry of multiple model species. Butterfly wing shape is species-specific and can influence mimetic signaling, but has not been characterized in this species. We used elliptical fourier analysis to investigate whether mimetic P. dardanus female forms have converged on the wing shape of their respective models. Although both models and mimics varied in forewing and hind wing shape, we found no evidence of forewing shape convergence between them. Overall, forewings did not differ in shape between sexes in P. dardanus, nor in four non-mimetic Papilio used for comparison. Similarly, there were no hind wing …

Automated Species Classification Methods For Passive Acoustic Monitoring Of Beaked Whales, John Lebien

LSU New Orleans Theses and Dissertations

The Littoral Acoustic Demonstration Center has collected passive acoustic monitoring data in the northern Gulf of Mexico since 2001. Recordings were made in 2007 near the Deepwater Horizon oil spill that provide a baseline for an extensive study of regional marine mammal populations in response to the disaster. Animal density estimates can be derived from detections of echolocation signals in the acoustic data. Beaked whales are of particular interest as they remain one of the least understood groups of marine mammals, and relatively few abundance estimates exist. Efficient methods for classifying detected echolocation transients are essential for mining long-term passive …

Neurocorrelates Of The Mirror Neuron System In Children With Chromosome 22q11.2 Deletion Syndrome, Ade Marais

LSU New Orleans Theses and Dissertations

Activation of brain regions that make up the mirror neuron system (MNS) is thought to reflect processing and perceiving behavior, action, and intentionality of other organisms. Sensing and perceiving motor behavior in others is an important component of understanding and participating in social interactions. Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) are diagnosed with serious medical, cognitive, and socio-emotional symptoms. Atypical development and function of the MNS may underpin some aspects of socio-emotional impairment and autism spectrum disorder (ASD)-like symptomology reported. This study of the MNS investigates differences in activation in the operculum, sensorimotor areas, and basal ganglia (BG) in …

Frameworks Of Recovery: Exploring The Intersection Of Policy & Decision-Making Processes After Hurricane Katrina, Kim Mosby

LSU New Orleans Theses and Dissertations

This study seeks to understand how local and national newspaper articles and African American residents frame obstacles to returning to New Orleans after Hurricane Katrina. It explores how recovery planning processes and policy changes influenced the decision-making processes of African Americans displaced to Houston through a content analysis of the media and qualitative interviews with displaced and returned residents. The study shows the media and participants framed disaster recovery policies as creating opportunities and gaps in assistance that varied by location. Participants described how policy decisions that created gaps in assistance compounded the difficulty of returning for working- and middle-class …

An Application Of M-Matrices To Preserve Bounded Positive Solutions To The Evolution Equations Of Biofilm Models, Richard S. Landry Jr.

LSU New Orleans Theses and Dissertations

In this work, we design a linear, two step implicit finite difference method to approximate the solutions of a biological system that describes the interaction between a microbial colony and a surrounding substrate. Three separate models are analyzed, all of which can be described as systems of partial differential equations (PDE)s with nonlinear diffusion and reaction, where the biological colony grows and decays based on the substrate bioavailability. The systems under investigation are all complex models describing the dynamics of biological films. In view of the difficulties to calculate analytical solutions of the models, we design here a numerical technique …

Exploring Science Identity: The Lived Experiences Of Underserved Students In A University Supplemental Science Program, Lynette D. Perrault

LSU New Orleans Theses and Dissertations

Underserved students attending under-resourced schools experience limited opportunities to engage in advanced science. An exploration into the influence a supplemental science program has on underserved students’ acquisition of science knowledge and skills to increase their pursuit of science was conducted to help explain science identity formation in students. The proliferation of supplemental science programs have emerged as a result of limited exposure and resources in science for underserved students, thus prompting further investigation into the influence supplemental science programs have on underserved students interest and motivation in science, attainment of science knowledge and skills, and confidence in science to promote …

Effect Of Cell Wall Destruction On Anaerobic Digestion Of Algal Biomass, Jessica R. Simpson

LSU New Orleans Theses and Dissertations

Research was conducted using algal biomass obtained from the surface of a secondary clarifier at Bridge City Wastewater Treatment Plant and subsequently sent through an electrochemical (EC) batch reactor at various concentrations. The first objective was to achieve maximum cell wall destruction electrochemically using the EC batch reactor and determine the optimal detention time and voltage/current relationship at which this occurred. The second objective was to subject two algal mediums to anaerobic digestion: the algal medium without electrochemical disinfection and the algal medium after disinfection. Every three days, for 12 days, total solids were measured from each apparatus to determine …

Design, Manufacture, And Structural Dynamic Analysis Of A Biomimetic Insect-Sized Wing For Micro Air Vehicles, Jose Enrique Rubio

LSU New Orleans Theses and Dissertations

The exceptional flying characteristics of airborne insects motivates the design of biomimetic wing structures that can exhibit a similar structural dynamic behavior. For this purpose, this investigation describes a method for both manufacturing a biomimetic insect-sized wing using the photolithography technique and analyzing its structural dynamic response. The geometry of a crane fly forewing (family Tipulidae) is acquired using a micro-computed tomography scanner. A computer-aided design model is generated from the measurements of the reconstructed scanned model of the insect wing to design the photomasks of the membrane and the venation network required for the photolithography procedure. A composite …

Underwater Acoustic Signal Analysis Toolkit, Kirk Bienvenu Jr

LSU New Orleans Theses and Dissertations

This project started early in the summer of 2016 when it became evident there was a need for an effective and efficient signal analysis toolkit for the Littoral Acoustic Demonstration Center Gulf Ecological Monitoring and Modeling (LADC-GEMM) Research Consortium. LADC-GEMM collected underwater acoustic data in the northern Gulf of Mexico during the summer of 2015 using Environmental Acoustic Recording Systems (EARS) buoys. Much of the visualization of data was handled through short scripts and executed through terminal commands, each time requiring the data to be loaded into memory and parameters to be fed through arguments. The vision was to develop …

Conflict, Constraint, And The Evolution Of The Multivariate Performance Phenotype, Ann M. Cespedes Phd

LSU New Orleans Theses and Dissertations

Performance is key to survival. From day-to-day foraging events, to reproductive activities, to life-or-death crises, how well an organism performs these tasks can determine success or failure. Selection, therefore, both natural and sexual, act upon performance, and performance demands on individuals shape a population’s morphological and physiological trait distributions. While studies of morphological adaptations to ecological pressures implicitly center on the idea that responses to selection improve performance via changes in morphology, the relationships between morphology, performance, and fitness are not always well understood. In this dissertation, I investigate these relationships explicitly, as well as determine the effects that different …

Nanomedicine For Immunosuppressive Therapy: Achievements In Pre-Clinical Research, Hanan Al-Lawati, Hamidreza Montazeri Aliabadi, Behzad Sharif Makhmalzadeh, Afsaneh Lavasanifar

Pharmacy Faculty Articles and Research

Introduction: Immunosuppression is the mainstay therapy in organ transplantation and autoimmune diseases. The effective clinical application of immunosuppressive agents has suffered from the emergence of systemic immunosuppression and/or individual drug side effects. Nanotechnology approaches may be used to modify the mentioned shortcomings by enhancing the delivery of immunosuppressants to target cells of the immune system, thus reducing the required dose for function, and/or reducing drug distribution to non-target tissues.

Areas covered: We provide an overview on the development of nanotechnology products for the most commonly used immunosuppressive agents. At first, the rationale for the use of nanoparticles as …

Complete Mitogenome Sequences Of Smooth Hammerhead Sharks, Sphyrna Zygaena, From The Eastern And Western Atlantic, Derek S. Guy, Cassandra L. Ruck, Jose V. Lopez, Mahmood S. Shivji

Biology Faculty Articles

We report the first mitogenome sequences of the circumglobally distributed, highly mobile, smooth hammerhead shark, Sphyrna zygaena, from the eastern and western Atlantic. Both genomes were 16,729 bp long with 13 protein-coding genes, two rRNAs, 22 tRNAs and a non-coding control region. The two Atlantic shark sequences differ from each other by 13 SNPs, and by 43 and 44 SNPs from the published mitogenome of an S. zygaena specimen from the eastern Pacific Ocean. The cross-Atlantic mitogenome sequences reported here provide a resource to assist with population genetics studies of this widely exploited species of conservation concern.

Infanticide In Chimpanzees: Taphonomic Case Studies From Gombe, Claire A. Kirchhoff, Michael L. Wison, Deus C. Mjungu, Jane Raphael, Shadrack Kamenya, D. Anthony Collins

Biological Sciences Faculty Research and Publications

Objectives

We present a study of skeletal damage to four chimpanzee (Pan troglodytes) infanticide victims from Gombe National Park, Tanzania. Skeletal analysis may provide insight into the adaptive significance of infanticide by examining whether nutritional benefits sufficiently explain infanticidal behavior. The nutritional hypothesis would be supported if bone survivorship rates and skeletal damage patterns are comparable to those of monkey prey. If not, other explanations, such as the resource competition hypothesis, should be considered.

Methods

Taphonomic assessment of two chimpanzee infants included description of breakage and surface modification, data on MNE, %MNE, and bone survivorship. Two additional infants …

Electrochemical Sensing Of Neurotransmitters With High Temporal And Spatial Resolution, Zhang Yueyue, Zuo Xiaolei, Fan Chunhai

Bulletin of Chinese Academy of Sciences (Chinese Version)

Currently, real time monitoring the release of neurotransmitters from living cells with high temporal and spatial resolution remains challenging. In recent years, quantitative analysis of neurotransmitter releasing has been achieved by developing different electrochemical monitoring techniques, and cell release patterns have been investigated. In addition, monitoring with high resolution and sensitivity can be achieved by modifying the electrode surface or regulating the electrode dimensions. The combining of different monitoring techniques can further improve the monitoring capability. This paper reviews the mechanism of electrochemical detection of neurotransmitter, the development of microelectrode and nanoelectrode for neurotransmitter detection, the coupling of electrochemical technology …