Digital Commons Network^™

Improving Provider Compliance With Adult Inflammatory Bowel Disease Patient Care Guidelines In The Ambulatory Setting Through The Use Of Electronic Health Records, Nana Bernasko

Yale School of Nursing Digital Theses

Electronic Health Record (EHR) systems have the ability to improve the quality of patient care, patient safety and provide benefits to providers and clinic practices. These systems can transform quality measurement and quality improvement methods, facilitate workflow, and track patients over time to ensure that they receive guideline-recommended, and evidence-based, care. Simply having an EHR system, however, may not be enough to improve the quality and safety of healthcare, especially if the system is not designed to include features specific to the treatment population. In terms of the complex care necessary to treat adult patients with inflammatory bowel disease (IBD), …

Iron Metabolism Genes In Browsing And Grazing Rhinoceroses: Implications For Iron Overload Disorder, Lorien Salyer

Undergraduate Honors Thesis Projects

Iron overload disorder is a serious condition that affects many animals of conservation interest, including rhinoceroses. Iron overload disorder is only found in browsing rhinos (African black, Diceros bicornis, and Sumatran, Dicerorhinus sumatrensis) but not in grazing species (African white, Ceratotherium simum, and greater one-horned, Rhinoceros unicornis). Iron overload is connected with many of the other health issues seen in captive browsing rhinoceroses, so it is vitally important that the iron metabolism process is studied to improve the existing husbandry procedures of these critically endangered animals. The objective of this study was to characterize genes related to …

Access And Affordability: The Textbook Conundrum, Peggy Seiden, Amy Mccoll

Library Staff Works

No abstract provided.

Local Wind Monitoring Matched With Lichen Pseudevernia Furfuracea (L.) Zopf Transplantation Technique To Assess The Environmental Impact Of A Biomass Power Plant, Lucio Lucadamo, Anna Corapi, Luana Gallo

Turkish Journal of Botany

The potential environmental impact of a biomass power plant (BPP) was evaluated by transplanting thalli of the lichen Pseudevernia furfuracea (L.) Zopf in the surrounding area for 3 months. Four meteorological stations were placed at four sites to monitor local winds. At the end of the period, thalli were retrieved and electrical conductivity percentage (EC%), lipid peroxidation, lichen vitality, photosynthetic efficiency, chlorophylls, xanthophylls+carotenoids, OD435/OD415, and concentrations of some elements frequently emitted by BPPs were measured. A univariate-multivariate analysis revealed clusters of sites with dissimilar mean values of ecophysiological parameters. They were merged, when not significantly differing, and classified as different …

Bioremediation Of Lead Using Spore Surface Displayed Proteins, Sofia M. Diaco

Honors Theses and Capstones

Lead is a toxic pollutant very harmful to human health since it accumulates in the body and affects the brain, liver, kidney, and bones. Fetuses can be exposed to lead during pregnancy, which can cause problems with learning later on in the baby’s life. The purpose of this project is to display a lead binding protein on bacterial spore surface for the bioremediation of lead from water. Spores from Bacillus subtilis are very robust and resistant to various harsh environments. Genetically fused to a spore surface protein, the displayed proteins demonstrate enhanced robustness and can be easily produced through sporulation …

Ligands Of Therapeutic Utility For The Liver X Receptors., Rajesh Komati, Dominick Spadoni, Shilong Zheng, Jayalakshmi Sridhar

Faculty and Staff Publications

Liver X receptors (LXRs) have been increasingly recognized as a potential therapeutic target to treat pathological conditions ranging from vascular and metabolic diseases, neurological degeneration, to cancers that are driven by lipid metabolism. Amidst intensifying efforts to discover ligands that act through LXRs to achieve the sought-after pharmacological outcomes, several lead compounds are already being tested in clinical trials for a variety of disease interventions. While more potent and selective LXR ligands continue to emerge from screening of small molecule libraries, rational design, and empirical medicinal chemistry approaches, challenges remain in minimizing undesirable effects of LXR activation on lipid metabolism. …

The Role Of The People’S Park In Promoting Conviviality And Quality Of Life In Increasingly Diverse Urban Neighbourhoods, María Beltrán Rodríguez, Madlen Simon

Artículos científicos

Especialmente en Europa, que durante mucho tiempo ha luchado por aceptar una población cada vez más diversificada, los barrios urbanos son cada vez más heterogéneos. El cambio se está acelerando a medida que la crisis en Medio Oriente empuja a los refugiados a las ciudades europeas. Esta diversificación actual tiene enormes implicaciones para la forma en que la gente utiliza los lugares públicos urbanos. La tipología del parque del pueblo es uno de los contextos donde esto se desarrollará. El parque del pueblo, caracterizado por la intención de diseñar espacios para y con todos los miembros de una comunidad, es …

The Old, The Young, And The Dehydrated: Comparing Dehydration Tolerance Of ‘Gransden’ And ‘Villersexel’ Ecotypes Of Physcomitrella Patens, Katherine Bollinger

Honors Thesis

Plant tolerance of environmental stresses such as water deficit depends on genetic factors that can vary in response to the climate in which the plants have evolved. Such genetically distinct populations of a species that live in different regions are referred to as ecotypes. The purpose of this research was to test the dehydration tolerance of two ecotypes of the moss species Physcomitrella patens, one from Little Gransden, England, which has been used for decades for research, and another more recently cultured ecotype from Villersexel, France. Little Gransden receives nearly half the yearly precipitation of Villersexel, which could have led …

Review Of Rice: Global Networks And New Histories, Ed. By Francesca Bray, Peter A. Coclanis, Edda L. Fields-Black, And Dagmar Schäfer, Andrew Sluyter

Faculty Publications

No abstract provided.

Entrepreneurial Choice: Restoring A Relevant Antitrust Policy, Warren Grimes

Case Western Reserve Law Review

No abstract provided.

Measuring Actual Behaviors In Hci Research – A Call To Action And An Example, Parker A. Williams, Jeffrey L. Jenkins, Joseph S. Valacich, Michael D. Byrd

Faculty Publications

There have been repeated calls for studies in behavioral science and human-computer interaction (HCI) research to measure participants’ actual behaviors. HCI research studies often use multiple constructs as perceived measures of behavior, which are captured using participants’ self-reports on surveys. Response biases, however, are a widespread threat to the validity of self-report measures. To mitigate this threat to validity, we propose that studies in HCI measure actual behaviors in appropriate contexts rather than solely perceptions. We report an example of using movements that reflect both actual behavior and behavioral changes measured within a health care IS usage context, specifically the …

Yale Medicine : Alumni Bulletin Of The School Of Medicine, Winter 2017, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the Winter 2017 issue of Yale Medicine: alumni bulletin of the School of Medicine, v. 51, no. 2. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965).

Novel Application Of Untargeted Metabolomics To Diseases Of Neurosurgical Significance, Alex Yang Lu

Yale Medicine Thesis Digital Library

Metabolomics, an emerging technique to study hundreds of small-molecule metabolites simultaneously, has been seldom applied to diseases of neurosurgical significance. We utilized metabolomics to explore two distinct questions: 1. to identify global metabolic changes and metabolite predictors of long-term outcome in aneurysmal subarachnoid hemorrhage (SAH) patients, 2. to identify differential metabolites profiles of radiation necrosis vs. recurrent tumor of metastatic brain lesions post-Gamma Knife radiosurgery. The first study applied gas chromatography time-of-flight mass spectrometry (GC-TOF) to cerebrospinal fluid samples collected from 15 high-grade aSAH patients (modified Fisher grades 3 and 4). Analysis was performed at two time points; metabolite levels …

Concussion Biomarker Discovery For Prognosis In Adolescent Athletes (Compete) Pilot Study, Sean N. Mbachu

Yale Medicine Thesis Digital Library

Concussion management in the ED is inconsistent due to a lack of available empirical testing. This project aims to assess the feasibility of a large multi-centered study for concussion biomarker discovery in the ED.

This prospective cohort pilot and feasibility study was conducted in the adult and pediatric EDs of an urban, academic, Level 1 trauma center. Twelve patients with concussions and twelve age- and gender-matched control patients presenting within 6 hours of an injury sustained during recreational activity were enrolled. ED blood specimens were banked for future proteomic analysis. Clinical outcomes were collected via online survey. Patient recruitment strategies …

The Evolution Of Restraint In American Psychiatry, Danilo Alejandro Rojas-Velasquez

Yale Medicine Thesis Digital Library

History/Social Science:

The Evolution of Restraint in American Psychiatry

Author: Danilo Rojas-Velasquez

In psychiatry, restraint generally refers to direct methods such as mechanical restraints or the use of drugs. Despite psychiatrists’ best efforts to utilize restraint judiciously, many patients still view it as the field’s defining feature, especially on inpatient units with involuntary commitment, medications against will, and locked doors. This essay is an attempt to understand the pervasiveness of restraint in psychiatry. It uses changes in the practices of restraint to examine the growth of the field over time. To accomplish this, the paper identifies three distinct regimes of …

Predicting Response To Anti-Pd-1 Immunotherapy In Metastatic Melanoma, James William Smithy

Yale Medicine Thesis Digital Library

Predictive biomarkers for antibodies against programmed death 1 (PD-1) remain a major unmet need in metastatic melanoma. Thus, we evaluated three alternative tissue- and blood based markers biomarkers for response to anti-PD-1 therapy. First, pre-treatment melanoma samples were assayed for expression of: 1) IRF-1, a PD-L1 transcription factor, as a proxy for a tumor’s capacity to express PD-L1, and 2) an immune activation panel consisting of CD3, Ki67, and Granzyme B to distinguish immune-active and immune-quiescent tumors. Additionally, we conducted pilot studies to determine the feasibility of measuring soluble PD-L1 in the plasma of cancer patients.

For tissue-based assays, samples …

Data Assimilation For Initialization Of Seasonal Forecasts, Magdalena A. Balmaseda

Journal of Marine Research

This article reviews the requirements for a data assimilation system from the perspective of initializing seasonal forecasts. It provides a historical perspective of the developments in ocean data assimilation and ocean observing systems. It also discusses the differences between state estimation and initialization, and presents a brief assessment of different initialization strategies. The value of assimilating ocean data to estimate the ocean state and to initialize seasonal forecasts is demonstrated. However, it is also shown that the assumption of unbiased models in conventional data assimilation methods is not suitable for the production of long temporal records of ocean initial states. …

The Hipaa Privacy Rule And The Eu Gdpr: Illustrative Comparisons, Stacey A. Tovino

Scholarly Works

In this Article, Professor Tovino compares and contrasts three illustrative concepts and rights in the Privacy Rule and/or the GDPR, including the concepts of authorization and consent, the rights of amendment and rectification, and the right to erasure. Identified similarities reflect the core values of HHS and the EU with respect to maintaining the confidentiality and privacy of personal data and protected health information, respectively. Identified differences reflect the Privacy Rule's original, narrow focus on health industry participants and individually identifiable health information compared to the GDPR's broad focus on data controllers and personal data. Other differences reflect, perhaps, the …

The Use And Abuse Of Mutual-Support Programs In Drug Courts, Sara Gordon

Scholarly Works

There is a large gap between what we know about the disease of addiction and its appropriate treatment, and the treatment received by individuals who are ordered into treatment as a condition of participation in drug court. Most medical professionals are not appropriately trained about addiction and most addiction treatment providers do not have the education and training necessary to provide appropriate evidence-based services to individuals who are referred by drug courts for addiction treatment. This disconnect between our understanding of addiction and available addiction treatment has wide-reaching impact for individuals who attempt to receive medical care for addiction in …

Using Feminist Theory To Advance Equal Justice Under Law, Linda L. Berger, Bridget J. Crawford, Kathryn M. Stanchi

Scholarly Works

This essay provides an overview of the purposes, themes and scholarly methodologies evidenced at the October 2016 conference, The U.S. Feminist Judgments Project: Writing the Law, Rewriting the Future, a two-day conference hosted by the Center for Constitutional Law at the University of Akron School of Law. This essay provides some of the background to the development of the path-breaking book, Feminist Judgments: Rewritten Opinions of the United States Supreme Court (Cambridge University Press, 2016). It also focuses attention on the importance of diversity on the bench, with a particular need for judges who understand or experience the intersecting …

Medicine@Yale January/February 2017 Volume 13, Issue 1, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.

Through The Lens Of The Reviewer: Information Literacy, An Lms, And Peer Review, Wendi M. Kappers

Publications

This research paper describes the use of peer review to improve information literacy. Peer-reviewed assignments for learning have been seen favorably within the literature. The articulated benefits range from students feeling more engaged, having expressed less anxiety, or found to be better equipped to perform in unfamiliar areas outside their current learning environments. However, minimal research examines the benefits specifically for the feedback provider (reviewer) when a more modern tool, such as the Canvas Learning Management System (LMS) is used. During the fall 2015 semester, a study was conducted to examine the peer review process from the vantage point of …

Nebraska Summary: S1140 John Deere 6110r, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2185: Case Ih Steiger 470 Rowtrac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2184: Case Ih Steiger 420 Rowtrac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2182: Claas Axion 860, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2181: Claas Axion 840, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2178: Kubota M7-171, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2188: Case Ih Steiger 540 Quadtrac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2187: Case Ih Steiger 500 Quadtrac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …