Digital Commons Network^™

Reciprocal Legitimation In The Federal Courts System, Neil S. Siegel

Faculty Scholarship

Much scholarship in law and political science has long understood the U.S. Supreme Court to be the “apex” court in the federal judicial system, and so to relate hierarchically to “lower” federal courts. On that top-down view, exemplified by the work of Alexander Bickel and many subsequent scholars, the Court is the principal, and lower federal courts are its faithful agents. Other scholarship takes a bottom-up approach, viewing lower federal courts as faithless agents or analyzing the “percolation” of issues in those courts before the Court decides. This Article identifies circumstances in which the relationship between the Court and other …

Insulin-Like Growth Factor Signaling Regulates Developmental Trajectory Associated With Diapause In Embryos Of The Annual Killifish Austrofundulus Limnaeus, S. Cody Woll, Jason E. Podrabsky

Biology Faculty Publications and Presentations

Annual killifishes exhibit a number of unique life history characters including the occurrence of embryonic diapause, unique cell movements associated with dispersion and subsequent reaggregation of the embryonic blastomeres, and a short postembryonic life span. Insulin-like growth factor (IGF) signaling is known to play a role in the regulation of metabolic dormancy in a number of animals but has not been explored in annual killifishes. The abundance of IGF proteins during development and the developmental effects of blocking IGF signaling by pharmacological inhibition of the insulin-like growth factor I receptor (IGF1R) were explored in embryos of the annual killifish Austrofundulus …

The Economics Of Healthcare Rationing, Michael D. Frakes, Matthew B. Frank, Kyle Rozema

Faculty Scholarship

This article examines the economics of healthcare rationing. We begin with an overview of the various dimensions across which healthcare rationing operates, or at least has the potential to operate, in the first place. We then describe the types of economic analyses used in healthcare rationing decision-making, with particular reference to cost-benefit analysis and cost-effectiveness analysis. We also discuss healthcare rationing in practice, such as how economic analyses inform decisions regarding which services to cover, and conclude by discussing various practical and conceptual challenges that may arise with economic analyses and that span both economics and ethics.

Risk Regulation And Innovation: The Case Of Rights-Encumbered Biomedical Data Silos, Arti K. Rai

Faculty Scholarship

Recent Supreme Court cases on patent-eligible subject matter are likely to exacerbate the longstanding problem of biomedical data fragmentation. For each data silo, multiple overlapping legal claims and claimants must be addressed to achieve the benefits of pooling.

Commentators who have discussed the data aggregation challenge have generally focused on possibilities created through public funding, through collective action by research participants, or through pressure by payers. This Article emphasizes the important role of risk regulators, most notably the precedent offered by risk regulation in the area of clinical trial data.

While U.S. risk regulators have taken some positive steps, the …

N.C. Medicaid Reform: A Bipartisan Path Forward, Barak D. Richman, Allison Rice

Faculty Scholarship

The North Carolina Medicaid program currently constitutes 32% of the state budget and provides insurance coverage to 18% of the state’s population. At the same time, 13% of North Carolinians remain uninsured, and even among the insured, significant health disparities persist across income, geography, education, and race.

The Duke University Bass Connections Medicaid Reform project gathered to consider how North Carolina could use its limited Medicaid dollars more effectively to reduce the incidence of poor health, improve access to healthcare, and reduce budgetary pressures on the state’s taxpayers.

This report is submitted to North Carolina’s policymakers and citizens. It assesses …

Convicting The Innocent Redux, Brandon L. Garrett

Faculty Scholarship

No abstract provided.

Creating A Data Resource: What Will It Take To Build A Medical Information Commons?, Patricia A. Deverka, Mary A. Majumder, Angela G. Villanueva, Margaret Anderson, Annette C. Bakker, Jessica Bardill, Eric Boerwinkle, Tania Bubela, Barbara J. Evans, Nanibaa’ A. Garrison, Richard A. Gibbs, Robert Gentleman, David Glazer, Melissa M. Goldstein, Hank Greely, Crane Harris, Bartha M. Knoppers, Barbara A. Koenig, Isaac S. Kohane, Salvatore La Rosa, John Mattison, Christopher J. O’Donnell, Arti K. Rai, Heidi L. Rehm, Laura L. Rodriguez, Robert Shelton, Tania Simoncelli, Sharon F. Terry, Michael S. Watson, John Wilbanks, Robert Cook-Deegan, Amy L. Mcguire

Faculty Scholarship

National and international public–private partnerships, consortia, and government initiatives are underway to collect and share genomic, personal, and healthcare data on a massive scale. Ideally, these efforts will contribute to the creation of a medical information commons (MIC), a comprehensive data resource that is widely available for both research and clinical uses. Stakeholder participation is essential in clarifying goals, deepening understanding of areas of complexity, and addressing long-standing policy concerns such as privacy and security and data ownership. This article describes eight core principles proposed by a diverse group of expert stakeholders to guide the formation of a successful, sustainable …

The U.S. Culture Collection Network Responding To The Requirements Of The Nagoya Protocol On Access And Benefit Sharing, Kevin Mccluskey, Katharine B. Barker, Hazel A. Barton, Kyria Boundy-Mills, Daniel R. Brown, Jonathan A. Coddington, Kevin Cook, Philippe Desmeth, David Geiser, Jessie A. Glaeser, Stephanie Greene, Seogchan Kang, Michael W. Lomas, Ulrich Melcher, Scott E. Miller, David R. Nobles Jr., Kristina J. Owens, Jerome H. Reichman, Manuela Da Silva, John Wertz, Cale Whitworth, David Smith

Faculty Scholarship

The U.S. Culture Collection Network held a meeting to share information about how culture collections are responding to the requirements of the recently enacted Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity (CBD). The meeting included representatives of many culture collections and other biological collections, the U.S. Department of State, U.S. Department of Agriculture, Secretariat of the CBD, interested scientific societies, and collection groups, including Scientific Collections International and the Global Genome Biodiversity Network. The participants learned about the policies of the United …

The Limits Of “Limitations And Exceptions” In Copyright Law, Jerome H. Reichman

Faculty Scholarship

The “designated exceptions” approach in the European Union and elsewhere becomes obsolete when faced with the needs of digital science to scrutinize and analyze all relevant research results pertinent to any scientific inquiry. Even the fair use exception rooted in U.S. law, while more agile on a case by case approach, is challenged by the scientific communities’ need to reproduce and analyze all available material relevant to any given research project and by the ability of automated knowledge discovery tools to do just that. A more promising model for reform is the “some rights reserved” concept of private ordering that …

Integrative Care Models: Impact On An Aging Society Chelsea Rink, Chelsea Rink

SPNHA Review

This paper explores the need for healthcare reform to support the aging population in the United States. In the literature review, the author identifies the unique needs of the aging population and explores the application of integrated care models in achieving the healthcare Triple Aim. Two alternative integrated care models for older adults in the United States are examined: the Program of All-Inclusive Care for the Elderly (PACE) and Tandem 365. Berwick, Nolan, and Whittington’s (2008) recommendations of key framework for integrated care models to achieve the Triple Aim are introduced and utilized to evaluate and compare PACE and Tandem …

Youth Work Supervision: Supporting Practice Through Reflection, Jocelyn Wiedow

Journal of Youth Development

The role of a youth work supervisor is critical in supporting frontline staff to develop and strengthen their skills to provide high-quality programs for youth. This article emphasizes the need for supervisors to create a staff-centered approach to reflection. Key elements of strong youth work supervision include building trust with staff, embedding reflection into supervisory practice, and seeking continued support to improve supervisory practice. Examples from the field illustrate how these components can look in practice.

A Rare Case Of Erythema Elevatum Diutinum Presenting As Diffuse Neuropathy, G H. Nguyen, E L. Guo, D Norris

Faculty, Staff and Students Publications

No abstract provided.

Biology Ii Lab, Megan Wagner

Syllabus Repository

No abstract provided.

Ambulatory Hemodynamic Monitoring Reduces Heart Failure Hospitalizations In "Real-World" Clinical Practice, Akshay S. Desai, Arvind Bhimaraj, Rita Jermyn, Jamie M. Pelzel

Articles

BACKGROUND:

In the CHAMPION (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in New York Heart Association [NYHA] Functional Class III Heart Failure Patients) trial, heart failure hospitalization (HFH) rates were lower in patients managed with guidance from an implantable pulmonary artery pressure sensor compared with usual care.

OBJECTIVES:

This study examined the effectiveness of ambulatory hemodynamic monitoring in reducing HFH outside of the clinical trial setting.

METHODS:

We conducted a retrospective cohort study using U.S. Medicare claims data from patients undergoing pulmonary artery pressure sensor implantation between June 1, 2014, and December 31, 2015. Rates of HFH …

Proceedings Of Eksig Conference 2017: Alive. Active. Adaptive, Elvin Karana

DRS Conference Volumes

No abstract provided.

The Effects Of Pornography On Gay, Bisexual, And Queer Men's Body Image: An Experimental Study, Neil Gleason

All Graduate Theses, Dissertations, and Other Capstone Projects

Because gay male pornography often depicts idealized images of male bodies and is widely consumed by gay men, recent studies have investigated the relationship between gay men's pornography consumption and body image. However, the limited research on the subject has reported conflicting results and has only utilized correlational and qualitative methodologies. This is this first known experimental study to investigate the impact of pornography on gay, bisexual, and queer men's body image. Eighty-seven gay, bisexual, and queer men were assigned to watch either an "amateur" pornographic video, "professional" pornographic video, or a nature video, and then completed several body image …

Weikangning Therapy In Functional Dyspepsia And The Protective Role Of Nrf2, Yujuan Chang, Wei Wei, Li Tong, Yanjun Liu, Aimin Zhou, Jiande Chen, Ruhan Wei, Ping Zhang, Xiaolan Su

Chemistry Faculty Publications

Functional dyspepsia (FD) is a non-organic gastro-intestinal disorder that has a marked negative impact on quality of life. Compared with conventional pharmacological therapies, the traditional Chinese medicine weikangning (WKN) is a safe and effective treatment for FD. The present study aimed to determine the molecular mechanisms underlying the efficacy of WKN. The effect of different concentrations of WKN on the proliferation of the human gastric mucosal epithelial cell line GES-1 was assessed. The optimal WKN concentration to promote cell proliferation was determined, and this concentration was used to examine the effect of WKN compared with a domperidone-treated positive control group …

Genetic Polymorphisms Of The Glucocorticoid Receptor And Interleulin-8 Receptor Genes And Their Relationship To Production Traits And Hair Coat Scores In Crossbred Cattle, Avery B. Deaton, Laura Meyer, Jeremy Powell, Charles F. Rosenkrans Jr.

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Little is understood about how the diversity of genes, specifically the glucocorticoid receptor (GR) and interleukin-8 receptor (CXCR2), are related to reproductive health and how this affects physical traits in cattle. Glucocorticoid receptors have been positively associated with higher milk yields, lactose content, feed intake, and feed conversion rates. Interleukin-8 genes are part of the innate immune response and help with many aspects of female reproductive health, such as protecting the embryo from the maternal immune system during pregnancy. The objective of this research was to identify polymorphisms in the GR and CXCR2 genes and to associate genotypes between the …

Hope Is A 4-Legged Word: How Service Dogs Can Help Veterans Suffering From Combat-Related Post Traumatic Stress Disorder, Holly Katherine Robinson

Undergraduate Honors Theses

As the rate of posttraumatic stress disorder (PTSD) continues to increase among our veterans returning from the War on Terror, the need for alternative treatment options is becoming more critical. One such alternative is the use of psychiatric service dogs specially trained to assist those living with PTSD. However, little empirical research has been conducted to support the legitimacy of this treatment option. This present study sought to explore the benefits that could be gained from the use of a service dog to treat PTSD by exploring relevant literature. The training the dogs receive as well as the possible problems …

Alternative Therapies For People With Special Needs: An Emphasis On Animal-Assisted Therapies, Emily Hamilton

Undergraduate Honors Theses

This paper contains research examining the effectiveness of alternative therapies - play therapy, art therapy, music therapy, horticulture therapy, and animal-assisted therapies – in helping various special needs populations. The focus of this research was on animal-assisted therapies that utilized therapy dogs or horses. These therapies provide a plethora of benefits physically, mentally, and psychologically. 11 interviews were conducted with counselors, psychologists, therapy dog owners, and an equine therapy director to further examine the effectiveness of these alternative therapy programs. Each interview presented unique evidence of the positive impact these therapies are having on various populations. All research into these …

A Comparison Of Traditional Epidural And Low-Dose Epidural Techniques, Ellen Terry

Undergraduate Honors Theses

The purpose of this thesis was to compare traditional epidural analgesia to other low-dose epidural analgesic techniques e.g. combined spinal-epidural analgesia and mobile epidural analgesia. The risk and side-effects of each type of epidural had on both mother and the newborn was researched and discussed. This was a comprehensive analysis of several studies dating from 1989 to 2016. It was found that traditional epidural analgesia increased the risk for cesarean deliveries, vaginal assisted deliveries, longer duration of labor, postpartum hemorrhage, breastfeeding cessation, higher temperature, lower maternal satisfaction and failed catheters. No effect on the newborn was found. Combined spinal was …

Innovation And Collaboration: Creating A Transdisciplinary Childhood Obesity Prevention Graduate Certificate Program, Becky Jensen, Mindy Anderson-Knott, Mary Bowne, Linda Boeckner, Suzanne Stluka, Kendra Kattelmann, Jessica Meendering

Health and Nutritional Sciences Faculty Publications

Preparing future professionals to work in transdisciplinary settings with a skill set to effectively foster collaborations and sustainable change requires a thoughtful and concerted interprofessional educational approach. Through an inter-university partnership in 2010 with name of university and the name of university, a group of faculty convened to propose the Transdisciplinary Obesity Prevention (TOP) graduate certificate program. With funding supported by a United States (US) Department of Agriculture (USDA) National Institute of Food and Agriculture grant in 2011, a team of faculty from name of university and name of university representing various disciplines (exercise science, nutrition, dietetics, health promotion, public …

Outlook Magazine, Autumn 2017

Outlook Magazine

No abstract provided.

Outlook Magazine, Winter 2017

Outlook Magazine

No abstract provided.

Annual Report Of The Registrar 2016/2017, University Of Northern Iowa

Institutional Effectiveness & Planning Documents

Contents:

--- Definitions
--- Some Comparisons
--- Annual Report Data
--- Summary of Attendance
--- Attendance by Session
--- Degrees Granted 2016/17
--- Degree Summary 2016/17
--- Program Certificates 2016/17
--- Miscellaneous Enrollment Information
--- Degrees Granted by College, Degree and Racial/Ethnic Classification

Ukraine V. Russia And Philippines V. China: Jurisdiction And Legitmacy, Peter Tzeng

Denver Journal of International Law & Policy

No abstract provided.

Developing A Feminist Pedagogy: A Look At Intersectionality And Poe's Women, Riley Haacke

Criterion: A Journal of Literary Criticism

Abstract

Edgar Allan Poe is one of the world’s most prolific writers and therefore has an immense capacity to influence and change how we, as a society, engage with literature. By developing a feminist pedagogy centered on the intersectionality of Poe’s diverse female characters we can begin to develop a value based education model that influences the critical conversations we have about women’s issues.

Risk Of Glucose Intolerance And Gestational Diabetes Mellitus In Relation To Maternal Habitual Snoring During Early Pregnancy., Chunfang Qiu, Wayne Lawrence, Bizu Gelaye, Lee Stoner, Ihunnaya O Frederick, Daniel A Enquobahrie, Tanya K Sorensen, Michelle A Williams

Articles, Abstracts, and Reports

BACKGROUND: Obstructive sleep apnea (OSA) or habitual snoring is known to be associated with impaired glucose tolerance and type 2 diabetes among both men and non-pregnant women. We examined the association of habitual snoring during early pregnancy with risk of impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM).

METHODS: A cohort of 1,579 women was interviewed during early pregnancy. We collected information about snoring frequency during early pregnancy. Results from screening and diagnostic tests for IGT and GDM were abstracted from medical records. Multivariate logistic regression models were fitted to estimate odds ratios (OR) and 95% confidence intervals (95% …

Annotation Of Alternatively Spliced Proteins And Transcripts With Protein-Folding Algorithms And Isoform-Level Functional Networks., Hongdong Li, Yang Zhang, Yuanfang Guan, Rajasree Menon, Gilbert S Omenn

Articles, Abstracts, and Reports

Tens of thousands of splice isoforms of proteins have been catalogued as predicted sequences from transcripts in humans and other species. Relatively few have been characterized biochemically or structurally. With the extensive development of protein bioinformatics, the characterization and modeling of isoform features, isoform functions, and isoform-level networks have advanced notably. Here we present applications of the I-TASSER family of algorithms for folding and functional predictions and the IsoFunc, MIsoMine, and Hisonet data resources for isoform-level analyses of network and pathway-based functional predictions and protein-protein interactions. Hopefully, predictions and insights from protein bioinformatics will stimulate many experimental validation studies.

Three Essays In Food Consumption And Health Related Issues, Fuad Mohammed Alagsam

Theses and Dissertations--Agricultural Economics

This dissertation consists of three essays that make contributions to the research on food consumption and health-related issues. Essay I elaborates on how the interactions of consumers’ beliefs and actions influence Food-Away-From-Home (FAFH) consumption and tests whether consumers compensate for the high caloric intake typically associated with FAFH by changing their behaviors during other meals. Essay II studies consumers’ choices related to time allocations for food consumption and tests how consumers’ lifestyles moderate the effect of secondary eating (eating while doing other activities) on obesity. Lastly, Essay III examines intertemporal choices, through which individuals make trade-offs between immediate gratifications and …