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Upper Limb Prosthesis: A Functional Replacement For The Biological Limb?, Ari Schacter

The Science Journal of the Lander College of Arts and Sciences

The 21st century continues to produce major advancements in prosthetic limb technology. Specifically, improvements to the myo-electric prosthesis have helped numerous upper limb amputees, especially transhumeral patients. Targeted muscle reinnervation surgery has allowed for more seamless control of the prosthetic device by creating new control centers for the unused nerves of the residual arm. Additionally, improvements in pattern recognition technology have enabled transhumeral amputees to gain more natural control of the prosthesis and consequently better imitate a biological limb. Another important development is in regards to the configuration and placement of electromyography electrodes on the amputee’s body. Using high-density electrodes …

The Relationship Between Periodontitis And Cardiovascular Disease, Jonathan Krupka

The Science Journal of the Lander College of Arts and Sciences

The relationship between periodontal disease and cardiovascular disease has been the subject of much research in recent years. The aim of this study is to review and analyze the relevant literature regarding this relationship, with an emphasis on determining a presence of periodontal bacteria from the periodontal pocket in atheromatous plaques, and to explore the biological role of inflammatory mechanisms that may link periodontitis and cardiovascular disease. Although there seems to be conflicting reports, the overall consensus confirms the presence of periodontal bacteria, such as Porphyromonas gingivalis, in atheromatous plaques. Additionally, the presence of systemic markers of cardiovascular disease in …

The Correlation Between Stress And The Development Of Dissociative Identity Disorder, Aviva Soibelman

The Science Journal of the Lander College of Arts and Sciences

Stress is a huge part of life. Our body responds to stress in different ways and most of the times the body overcomes the stress. There are a few incidents when the body is not capable of dealing with the stress and the toll it takes on the brain is undeniable. One result of intolerable stress is Dissociative Identity Disorder (DID) in which biopsychology comes to life, as we see how the body is affected by psychology, and vice versa. The mediators that help the body adapt to stressors become detrimental when a person faces trauma or chronic stress. Glucocorticoids, …

Full Issue: Volume 11, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Luteinizing Hormone And Alzheimer’S Disease: Impact And Possibilities Of Treatment, Rachel Walkin

The Science Journal of the Lander College of Arts and Sciences

Alzheimer’s disease is a common neurodegenerative disease that is the 6th leading cause of death in the United States. An estimated 5 million Americans are afflicted nationwide and the cost to the economy is valued at 259 billion dollars. Additionally, unlike other major causes of death in the United States, there is no treatment for Alzheimer’s Disease. Alzheimer’s is a progressive disease and it is strongly tied to aging. In most cases symptoms make their first appearance in the late 60’s and gradually worsen, eventually leading to a loss of cognitive function and death. The two outstanding changes in the …

Cyclodextrin As A Drug Carrier Increasing Drug Solubility, Malka Silberberg

The Science Journal of the Lander College of Arts and Sciences

The development of a new drug requires research and evaluation before the drug is approved to enter the market. One of the factors determining the efficacy of a drug is the aqueous solubility of the drug. A current problem in today’s pharmaceutical industry is the low aqueous solubility of many useful drugs. A drug with a low aqueous solubility will not readily be absorbed by the body. The low aqueous solubility of a drug is often due to the drug’s hydrophobic character. Drug enhancement methods are necessary to avoid the obstacle of drug insolubility and many methods have been developed. …

Is Gene Therapy A Viable Option For Cancer Treatment?, Aliza Applebaum

The Science Journal of the Lander College of Arts and Sciences

The use of gene therapy as a medical treatment option was first introduced to the world in 1990, when a four-year-old girl became its first patient. Since then gene therapy has met great success but also severe drawback. Incidences with severely negative outcomes on patients gave gene therapy a bad name and many began skeptical towards its use, but the constant work and progress on the safety and effectiveness of gene therapy is making it a more viable route of treatment. This paper focuses on gene therapy as a form of cancer treatment. Viral insertion of the modified genetic material …

Should Genetic Testing Be Recommended For Long Qt Syndrome Patients And Their Relatives?, Menachem Braun

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Consequences Of Untreated Obstructive Sleep Apnea, Binyamin S. Kanter

The Science Journal of the Lander College of Arts and Sciences

Over the past few years, awareness of the prevalence of obstructive sleep apnea has significantly increased. Indeed, sleep apnea may be more common now with the increasing incidence of obesity and the growing number of elderly individuals in our population. How serious is this condition, and what are the potential long-term effects and consequences of obstructive sleep apnea if left untreated? An overlap of many serious conditions with obstructive sleep apnea has been noticed. These conditions include hypertension, heart disease and failure, stroke, diabetes, neurological diseases, depression, and a number of other serious health concerns. The purpose of this paper …

Structure-Reactivity Relationship Of Bio-Inspired Copper Complexes Containing Polypyridylamine Derivatives, Pattira Suktanarak

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this dissertation, bio-inspired copper complexes were designed to study the influence from ligands, nuclearity, solvents and secondary coordination on reactivity toward small-molecule activation. This structure-reactivity relationship was examined in oxygen reduction reac­tions (ORR), and applied in detection of ascorbic acid (AsH2). First, copper(II) complexes containing polypyridyl-derivative ligands (i.e., Cu(dpa), Cu(adpa) and Cu2(addpa)) were synthesized and fully characterized by X-ray crystallography. The Cu(I) complexes which are active species for ORR were generated using AsH2 as a reducing agent. Redox states of the metal were examined by UV-Vis, NMR and EPR. It was found that copper complexes with various ligand topologies …

Development Of Emulsion-Based Adjuvants For Parenteral Influenza Vaccines, Sakalanunt Lamaisakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Generally, inactivated whole-cell and subunit vaccines are often less antigenic than live-attenuated vaccines, then they require the inclusion of adjuvants to improve immunostimulating activities. In the present study, microemulsion (ME) and nanoemulsion adjuvants were developed to evoke a safety and effective immune response of vaccine antigens. The emulsion systems including vegetable oil and nonionic surfactants have been formulated with or without cationic surfactant, cetyltrimethylammonium bromide (CTAB) and then sterilized by autoclaving. Physical properties, hemolytic activities and biological efficacies of all prepared emulsions were conducted. The results demonstrated that the autoclaving process caused a reduction in droplet size with narrow size …

American Chemical Society (Acs) Legacy Archives, Ucf Libraries

Technology Fee Funded Projects

The UCF Libraries is requesting $98,835 ($101,835-$3,000 cost share) for the one-time purchase of the American Chemical Society (ACS) Legacy Archives.

Novel Myopia Genes And Pathways Identified From Syndromic Forms Of Myopia, Daniel Ian Flitcroft, James Loughman, Christine Wildsoet, Cathy Williams, Jeremy A. Guggenheim

Articles

PURPOSE. To test the hypothesis that genes known to cause clinical syndromes featuring myopia also harbor polymorphisms contributing to nonsyndromic refractive errors. METHODS. Clinical phenotypes and syndromes that have refractive errors as a recognized feature were identified using the Online Mendelian Inheritance in Man (OMIM) database. One hundred fifty-four unique causative genes were identified, of which 119 were specifically linked with myopia and 114 represented syndromic myopia (i.e., myopia and at least one other clinical feature). Myopia was the only refractive error listed for 98 genes and hyperopia and the only refractive error noted for 28 genes, with the remaining …

The Mobius Strip Of Total Health: Manipulation Of Thinking Prior To Exercise Activity, Joseph A. Schenk

Honors College Theses

Research shows mental and physical health are interdependent. We sought to test various methods of external motivation to effect change in the physical performance and mental health of students enrolled in walking classes. We hypothesized that if there was a correlation between physical exercise and mental health and we could motivate individuals to exercise, then that motivation would in turn result in better mental health. Participants, 19 in the pilot and 320 in the main study, were randomly assigned into three groups to receive messages prior to conducting physical activity: those who received neutral messages about exercise, those who received …

Inbreeding Depression In The Introduced Spider Latrodectus Geometricus, Margaret A. Howard

Honors College Theses

The brown widow spider (Latrodectus geometricus) is thought to be native to South America or Southern Africa, but its distribution has expanded to most continents by human introduction. In the continental USA, L. geometricus was first documented in south Florida in the 1930’s. In the early 2000’s a population expansion occurred, and this species is now found in Florida, Georgia, South Carolina, Alabama, Mississippi, Louisiana, Texas, and southern California. Introduced species may face many obstacles when establishing a new population. One common obstacle might be severe inbreeding following founder events or genetic bottlenecks. The purpose of this study was …

Determining The Reproductive Patterns Of The Titan Acorn Barnacle (Megabalanus Coccopoma) In Its Introduced Range, Isabel L. Moran Ms.

Honors College Theses

Invasive species are a significant conservation concern given their contribution to native species decline. The barnacle, Megabalanus coccopoma, is a common invasive species in tropical and subtropical regions of both the Pacific and Atlantic oceans. Little is known about the life history and ecology of M. coccopoma, and data on reproductive biology could provide valuable insight into its propensity to establish introduced populations. Most species of barnacle (including M. coccopoma) are hermaphroditic, but self-fertilization is rare in species studied to date. A recent genetic study of introduced M. coccopoma populations in the southeastern US showed high levels of …

Community-Based Learning: A Primer, Zeinab Bedri, Ruairí De Fréin, Geraldine Dowling

Irish Journal of Academic Practice

Employers are increasingly demanding graduates with industry-ready communication, leadership, emotional intelligence and social ethics skills. Community-based learning (CBL) is a pedagogical approach which has tremendous potential to produce graduates with these attributes. However, for many early-career lecturers, distilling the insights from the teaching and learning literature, and then producing a well-designed CBL module, can be an intimidating task. What is missing is a primer which presents the core ideas of CBL in a way that is independent of subject-specific jargon. Ideally, this primer should provide the reader with the means of either drafting an initial project plan or, at the …

Blow Fly (Diptera: Calliphoridae) Responses To Different Colors Of Baited Traps, Oluwadamilola Olufunso Oke

Honors College Theses

Blow flies (Diptera: Calliphoridae) are usually the first insects to colonize human remains. By determining the time of colonization, a postmortem interval (PMI), or “time of death”, can be estimated. To develop more accurate PMI estimates, it is important for forensic entomologists to understand the cues that Blow flies use to locate vertebrate remains. The purpose of this study was to determine whether Blow flies use visual cues, in addition to olfactory cues, to locate carrion. Two colors of fly traps, clear and green, were constructed and chicken gizzard used as bait. Three Blow fly species exhibited a significant preference …

Testing The Optomotor Response In Sepia Bandensis, Lauren E. Thompson

Honors College Theses

Cephalopods (octopus, squid, and cuttlefish) have commonly been used as models to test visual function and camouflage due to their similarity in eye morphology with humans and because of their readily observable changes in body color in response to visual stimuli. Most studies have used a single species, Sepia officinalis, to make broad conclusions about camouflage and vision. However, these generalizations may not be applicable to all species. Here, I have examined visual function of the dwarf cuttlefish (Sepia bandensis), which differs from S. officinalis in habitat, geographic range, and size. Using the optomotor response, I quantified …

Gloria Anzaldúa’S El Mundo Zurdo: The Necessity Of A Historical Assessment, Malik Raymond

Honors College Theses

This thesis revolves around Chicana lesbian feminist Gloria Anzaldúa and one of her more important theories, El Mundo Zurdo. El Mundo Zurdo was a theory that focused on the marginalized people and the need for unity amongst them; however, up to this point, no historical analysis has been done on this theory. Through piecing together information from interviews and Anzaldúa’s literature, this thesis serves as a biography of her first forty years of life to address from where the theory came and becomes a bridge to link Anzaldúa to the wider Chicana, Third World feminist, and gay and lesbian …

Sex Education: Funding Facts, Not Fear, Rachel Rubenstein

Health Matrix: The Journal of Law-Medicine

The article offers information on the funding sex education programs enacted by the government for teaching about abstinence as the best method for avoiding sexually transmitted diseases and unintended pregnancy and risks factors associated with it in the U.S. Topics discussed include analysis of California Healthy Youth Act as a model for adequate sex education; different forms of sex education; and enactment of Abstinence Education Grant Program for the same.

Towards A Model Of Internal/External Motivation To Respond Without Prejudice: An Examination Of White Racial Identity And Affect, Christina Barnett

Theses and Dissertations

The current study explored how White racial identity influences the relationship between affective reactions to racism and one’s internal or external motivation to respond without prejudice. The first aim was to examine the bivariate relationships between White racial identity ego schemas and affective reactions to racism. The second aim examined the bivariate relationships between affective reactions to racism and an internal/external motivation to respond without prejudice. The third aim explored whether Phase I or Phase II White racial identity ego schemas explained the relation of affective reactions to racism and internal/external motivation to respond without prejudice. PROCESS mediation models were …

Time To Refocus Assessment Of Vision In Older Adults? Contrast Sensitivity But Not Visual Acuity Is Associated With Gait In Older Adults, James Loughman, Eoin Duggan, Orna Donoghue,, Rose Anne Kenny, Hilary Cronin, Ciarán Finucane

Articles

Background:

The relationship between measures of visual function and gait related risk factors for falls is unclear. In this study, we examine the relationship between visual function (visual acuity [VA] and contrast sensitivity [CS] at multiple spatial frequencies) and quantitative spatiotemporal gait, using a large, nationally representative sample of community dwelling older adults.

Methods: Participants aged 50 and over were recruited as part of The Irish Longitudinal Study on Ageing (TILDA). VA was measured with the LogMAR chart according to the Early Treatment of Diabetic Retinopathy Study protocol. CS was measured at five spatial frequencies ranging 1.5 to 18 cycles …

Novel Myopia Genes And Pathways Identified From Syndromic Forms Of Myopia, Daniel Ian Flitcroft, James Loughman, Christine F. Wildsoet, Cathy Williams, Jeremy A. Guggenheim

Articles

Clinical phenotypes and syndromes that have refractive errors as a recognized feature were identified using the Online Mendelian Inheritance in Man (OMIM) database. One hundred fifty-four unique causative genes were identified, of which 119 were specifically linked with myopia and 114 represented syndromic myopia (i.e., myopia and at least one other clinical feature). Myopia was the only refractive error listed for 98 genes and hyperopia and the only refractive error noted for 28 genes, with the remaining 28 genes linked to phenotypes with multiple forms of refractive error. Pathway analysis was carried out to find biological processes overrepresented within these …

Novel Myopia Genes And Pathways Identified From Syndromic Forms Of Myopia, Daniel Ian Flitcroft, James Loughman, Christine F. Wildsoet, Cathy Williams, Jeremy A. Guggenheim

Articles

P URPOSE . To test the hypothesis that genes known to cause clinical syndromes featuring myopia also harbor polymorphisms contributing to nonsyndromic refractive errors.

Ending Disparities And Achieving Justice For Individuals With Mental Disabilities, Robert K. Goldman, Sheila Shea

Scholarly Articles in Law Reviews & Journals

No abstract provided.

Parental Understandings Of The Meaning Of Autism Spectrum Disorder (Asd), Kylara Leyva

Open Access Theses & Dissertations

This study examines how parents understand autism, their child's behavior and development. Parents can understand their child's behavior and development through a medical model perspective, which sees the childâ??s autism as a series of deficits and deviations. However, a growing number of parents understand their child's behavior and development through a neurodiversity perspective, where a child is seen as having differences in behavior, instead of deficits. Parents' understandings of autism can influence how they see their child's behavior and development and be a driver for seeking diagnosis. In-depth interviews were conducted with parents of children with autism to probe for …

Sticker Shock: Standards And Disputes Of Gmo Food Labeling, David A. Hutchison

Emory International Law Review Recent Developments

The debate regarding the potential of genetically modified organisms (GMOs) and their application to genetically engineered foods has gone on for decades. As more consumer products that are the complete or partial result of GMO processes are introduced into markets, the controversy over GMO foods will continue to intensify. One of the primary areas of contention has been legislating how, if at all, to label these foods. This Essay will focus on some of the legal aspects of the debate that stem from the scientific concerns about GMOs and how these concerns affect the regulation of labeling such GMO products …

Implementing Medicaid Health Homes To Provide Medication Assisted Treatment To Opioid Dependent Medicaid Beneficiaries, Page M. Smith

Kentucky Law Journal

No abstract provided.

Academic Freedom As The Freedom To Do Academic Work, David Moshman

Department of Psychology: Faculty Publications

Academic freedom is defined as the freedom to do academic work. It follows that academic freedom (1) includes freedoms of teaching, learning, and inquiry; (2) is a type of intellectual freedom; (3) is specific to academic roles and contexts; (4) is crucial at all levels of education and in all other academic contexts; (5) is individual, collective, and institutional; and (6) is central to the academic integrity of any academic endeavor or institution. This conception, which coordinates multiple traditions and literatures, enables us to explain the nature and limits of academic freedom and to justify it as a necessity for …