Digital Commons Network^™

Live Long And Prosper: Plant–Soil Feedback, Lifespan, And Landscape Abundance Covary, Andrew Kulmatiski, Karen H. Beard, Jeanette M. Norton, Justin Heavilin, Leslie E. Forero, Josephine Grenzer

Wildland Resources Faculty Publications

Plant soil feedbacks (PSFs) are thought to be important to plant growth and species coexistence, but most support for these hypotheses is derived from short-term greenhouse experiments. Here we use a seven-year, common garden experiment to measure PSFs for seven native and six nonnative species common to the western United States. We use these long-term, field-based estimates to test correlations between PSF and plant landscape abundance, species origin, functional type, and lifespan. To assess potential PSF mechanisms, we also measured soil microbial community composition, root biomass, nitrogen cycling, bulk density, penetration resistance, and shear strength. Plant abundance on the landscape …

A Customized Quantitative Pcr Microrna Panel Provides A Technically Robust Context For Studying Neurodegenerative Disease Biomarkers And Indicates A High Correlation Between Cerebrospinal Fluid And Choroid Plexus Microrna Expression, Wang-Xia Wang, David W. Fardo, Gregory A. Jicha, Peter T. Nelson

Sanders-Brown Center on Aging Faculty Publications

MicroRNA (miRNA) expression varies in association with different tissue types and in diseases. Having been found in body fluids including blood and cerebrospinal fluid (CSF), miRNAs constitute potential biomarkers. CSF miRNAs have been proposed as biomarkers for neurodegenerative diseases; however, there is a lack of consensus about the best candidate miRNA biomarkers and there has been variability in results from different research centers, perhaps due to technical factors. Here, we sought to optimize technical parameters for CSF miRNA studies. We examined different RNA isolation methods and performed miRNA expression profiling with TaqMan® miRNA Arrays. More specifically, we developed a customized …

Analyzing Coxsackievirus B3 Genomic Rna By Site Directed Mutagenesis And Shape Analysis, Sara Smith

Theses/Capstones/Creative Projects

Virulent Coxsackievirus B3 (CVB3) is linked to myocarditis, pancreatitis, and type I diabetes. Avirulent CVB3 doesn’t cause disease. CVB3 possesses a positive, single-stranded ribonucleic acid (RNA) genome containing 7,400 nucleotides, organized into four sections: a 5’ untranslated region (5’ UTR), a single open reading frame, a 3’ untranslated region, and a poly-A tail. The 5’ UTR is 743 nucleotides divided into 7 domains. Mutations within the 5’ UTR can alter RNA structure, and thus alter virulence. Nucleotide associations responsible for higher level RNA folding patterns and structure haven’t been defined. We are investigating the 5’ UTR by selective 2’ hydroxyl …

Testing The Effectiveness Of Two Natural Selection Simulations In The Context Of A Large‑Enrollment Undergraduate Laboratory Class, Denise S. Pope, Caleb M. Rounds, Jody Clarke-Midura

Instructional Technology and Learning Sciences Faculty Publications

Background: Simulations can be an active and engaging way for students to learn about natural selection, and many have been developed, including both physical and virtual simulations. In this study we assessed the student experience of, and learning from, two natural selection simulations, one physical and one virtual, in a large enrollment introductory biology lab course. We assigned students to treatments (the physical or virtual simulation activity) by section and assessed their understanding of natural selection using a multiple-choice pre-/post-test and short-answer responses on a post-lab assignment. We assessed student experience of the activities through structured observations and an affective …

Ecog-Acrin (E4805) Randomized Phase Ii Study To Determine The Effect Of 2 Different Doses Of Aflibercept In Patients With Metastatic Renal Cell Carcinoma, Roberto Pili, Opeyemi Jegede, Michael A. Carducci, Judith Manola, David L. Groteluschen, Leonard L. Appleman, Glenn Liu, James C. Shanks, Shaker R. Dakhil, Janice Dutcher, Robert S. Dipaola

Internal Medicine Faculty Publications

Background—Aflibercept is a recombinantly-produced fusion protein that has potent anti-VEGF activity. We tested whether aflibercept has clinical activity in clear cell renal cell carcinoma (ccRCC). The recommended Phase 2 dose was 4 mg/kg but several patients treated at 1 mg/kg demonstrated prolonged progression-free survival (PFS). We therefore tested both doses in a parallel group randomized trial.

Methods—Eligible patients (pts) had histologically confirmed advanced or metastatic ccRCC and previous treatments including prior exposure to a VEGF RTKI. Patients received aflibercept (either 1 mg/kg or 4 mg/kg) day 1 of a 14-day cycle until progression. Patients randomized to 1 mg/kg …

Examining Movement Dynamics Of The Gulf Menhaden Fishery Using An Individual-Based Model, Robert D. Trigg Iii

Master's Theses

This study investigates the movement and harvest dynamics of the Gulf Menhaden Brevoortia patronus fishery. The fishery-dependent data collected by NOAA (years 2006-2009 and 2011) describe vessel-specific information on catch locations (latitude and longitude) and magnitude of harvest in metric tons (mt). A series of probability distribution functions (PDFs) were fit to the frequency distributions of number of harvests per day (Poisson), between-harvest distances (gamma), and harvest magnitude (log-normal). These analyses were used to inform an individual-based model (IBM). The IBM was run under several different spatial restriction regimes, including (1) current regulations in Texas, Louisiana, Mississippi, and Alabama; (2) …

Determination And Quantification Of Lead Content In Mammut Americanus Dentine Material By Anodic Stripping Voltammetry, Emma R. Shipley

Mastodon Tusk Project Posters

A 120,000-200,000 year old mastodon tusk of species Mammut americanus, recovered from Hampton, Iowa in 1933 (right) was tested for lead using a lead test from Home Depot.1 The lead test was returned positive, so Anodic Stripping Voltammetry (ASV) was undertaken to determine the concentration of lead in the dentine material of the tusk. The lead concentration is of interest because lead could affect both the health of the conservator and researchers and also inform about the diet of the mastodon. Tusk dentine material (left) functions similarly to human teeth, and studies have shown that 90% of lead in the …

Sem/Edx Chemical Composition Map Of Mastodon Tusk, Juliana Herran

Mastodon Tusk Project Posters

The goal of this project was to study one of the rarest objects in the collection of the UNI museum dating to the Aftonian or Yarmouth age (around 120,000 to 200,000 years old).

The tusk is 11 feet, 7.5 inches with a circumference at the proximal end of 2 feet, 2 inches.

There have been previous attempts of restoration of this tusk but there are not specific procedures on record that specify the materials or methods used during the restoration attempts with sufficient detail.

With the support of the Carver Grant awarded to the UNI museum, research teams containing students …

Domestic Relations, Barry B. Mcgough, Elinor H. Hitt, Abigail M. Herrmann

Mercer Law Review

This Article addresses significant case law during the survey period from June 1, 2016 through May 31, 2017.

A Risk-Based Method For Estimating The Carbon Sequestration Budget For A Mixed Hardwood Forest, Erin Cooper

Chemical Engineering Undergraduate Honors Theses

Carbon Dioxide (CO₂) levels in the atmosphere have risen from approximately 310 ppm in the 1950’s to over 400 ppm as of 2015. This rise in CO₂ has likely resulted in the observed warming trend of the earth’s atmosphere in the same time frame, causing significant concern in the scientific community. Several mitigation strategies have arisen to combat the upward trend of CO₂ emissions in recent decades, among them being carbon sequestration- the process of capturing CO₂ from the atmosphere and holding it for an extended period of time. This study used the U.S. Forest …

Global Marine Carbon Export Production During Eocene Hyperthermal Events, Angela Ruth Lewis

Earth & Environmental Sciences Theses - Archive

Early Eocene hyperthermal events can be an analog for global warming. Pelagic marine barite in deep sea sediment is a proxy for marine export production of organic matter into the deep ocean. Pelagic marine barite accumulation rates (BAR) were reconstructed over the Paleocene – Eocene Thermal Maximum (PETM; ~55.5 million years ago), Eocene Thermal Maximum 2 (ETM2; ~53.7 Ma) and ETM3 (~52.4 Ma) from ODP Sites 1209, 1215 and 1263. Northern Atlantic samples (with high detrital content) were acid digested and analyzed to reconstruct biogenic Ba (Ba/Al, Ba/Ti) and compare with elemental data from high resolution X-ray fluorescence. This data …

Effectiveness Of Chain Link Turtle Fence And Culverts In Reducing Turtle Mortality And Providing Connectivity Along U.S. Hwy 83, Valentine National Wildlife Refuge, Nebraska, Usa, Marcel P. Huijser, Kari E. Gunson, Elizabeth R. Fairbank

Nebraska Department of Transportation: Research Reports

We evaluated the effectiveness of existing turtle fences through collecting and analyzing turtle mortality data along U.S. Hwy 83, in and around Valentine National Wildlife Refuge, Nebraska, USA. We also investigated the level of connectivity for turtles provided through the culverts that were originally designed to pass water through a capture-mark-recapture experiment. While fenced valley sections had 33.1% fewer turtle observations than unfenced valley sections, the difference was not significant. However, we think that the effectiveness of the fence can be improved through fence repairs, other modifications of the fences, vegetation maintenance, and extending the length of the fences. Four …

Development And Characterization Of Rice Genotypes For Water Use Efficiency And Drought Resistance, Anuj Kumar

Graduate Theses and Dissertations

Rice, the second largest staple food crop, uses 30% of global fresh water to complete its life cycle worldwide. Water deficits worldwide have become a serious problem affecting rice growth and ultimately grain yield. To solve the water problem globally, improvement of water use efficiency (WUE) and other drought resistance (DR) traits in rice genotypes would be a useful strategy using advanced genomics tools. In this study, our objectives were to 1) analyze phenotypes of the USDA rice mini-core collection (URMC) for WUE and DR related traits, 2) correlate drought response phenes for physiological traits and grain yield in the …

Evaluation Of The Impact Of Tart Cherries Polyphenols On The Human Gut Microbiota And Phenolic Metabolites In Vitro And In Vivo, Alba Claudia Mayta-Apaza

Graduate Theses and Dissertations

Tart cherries are polyphenol abundant stone fruits claimed to exert health benefits further of its nutritional properties. The abundant phytochemicals content in tart cherries also referred as dietary polyphenols have been considered as an effective natural antioxidant when added in daily diet. However, it has been hypothesized the intervention of gut microbiota on the overall functionality of such compounds. This thesis contains a wide-ranging literature review focused on tart cherry as a crop, current market, functional food, and several health benefits. Furthermore, the research done describes and in vitro and in vivo assays of a short-term dietary intervention of tart …

A Molecular Diagnostic Survey Of Pathogens And Parasites Of Honey Bees, Apis Mellifera L., From Arkansas And Oklahoma, Dylan Cleary

Graduate Theses and Dissertations

The health and viability of colonies of the honey bee, Apis mellifera, in the United States have fluctuated dramatically over the past decade. This poses a substantial threat to agricultural production in this country. Currently, no single factor has been identified for this decline. Rather, it has been suggested that the interaction between multiple biotic and abiotic stressors may be responsible. Among these factors are pesticides, habitat loss, climate and weather, parasites and pathogens, and colony management techniques. For this reason, it is important to examine the prevalence of honey bee parasite and pathogen infection at the state level in …

A Microdebitage Analysis Of The Winterville Mounds Site (22ws500), Stephanie Leigh-Ann Guest

Master's Theses

The Winterville Mounds site (22WS500) was a civic ceremonial center of 23 mounds and is located near Greenville in northwest Mississippi. Winterville excavations as field schools are ongoing since 2005 under the direction of Dr. H. Edwin Jackson of The University of Southern Mississippi. Examination of the >1/4" (6.35 mm) mesh screened lithic material provided mixed results of reduction stages and lacked variety of non-local materials (Guest 2006, Winter 2009, McClendon 2012). Authors of these analyses called for the examination of the 1/16” (1.58 mm) water-screened lithic material to identify reduction stages and traces of non-local materials to provide evidence …

Effects Of Temperature On Growth And Molting In Blue Crabs (Callinectes Sapidus) And Lesser Blue Crabs (Callinectes Similis), Abigail Ann Kuhn

Master's Theses

Temperature can exert impacts on many processes in ectotherms. With global temperatures rising due to climate change, many ectothermic species may exhibit changes in growth rates and size at maturity, and these changes can have population-level effects. Predicting responses of species to climate change will require not only knowledge of thermal tolerance limits, but also effects of temperature change on growth rates and other life history parameters. For arthropods that exhibit discontinuous growth (i.e., molting), this includes both intermolt period and growth per molt. Previous laboratory and field experiments suggest that temperature affects both intermolt period (IMP) and growth per …

Reassessment Of The Red Drum Stock In Mississippi Coastal Waters: The Role Of Ages 3-5 Year-Class Fish, Emily Satterfield

Master's Theses

Red Drum, Sciaenops ocellatus, are highly sought after by sport fishermen in Mississippi coastal waters. In 2016, Mississippi anglers made over 180,000 fishing trips targeting Red Drum, making it the second most targeted marine species. The current Fishery Management Plan of the Gulf of Mexico Fishery Management Council, prohibits harvest of Red Drum in federal waters. Monitoring of the stock in Mississippi state waters occurs at sites that are almost exclusively estuarine, using gear types selective for juvenile fish. Additional samples come from the for-hire-industry that typically targets larger Red Drum. This project’s goal was to target age three …

Combined Effects Of Dissolved Oxygen And Temperature On Aerobic Respiration And Respiratory Recovery Responses Of The Spioniform Polychaete, Streblospio Gynobranchiata, In Relation To Body Size, Alyssa Bennett

Master's Theses

Elevated surface temperatures exacerbate the threat of hypoxia within coastal ecosystems. These two primary stressors likely interact as they elicit opposing physiological responses from marine organisms. Metabolic depression is typically associated with hypoxia, while metabolic rates increase with temperature. Moreover, physiological effects of combined stressors may not be additive. In light of increasing pressures from hypoxia, elevated ocean temperatures, and other stressors within coastal regions, studies need to examine effects of multiple stressors on physiology of coastal organisms.

Mass-specific aerobic respiration (V_O2) was characterized as a proxy for metabolic cost of Streblospio gynobranchiata, at combined levels of …

Modulation Of Photonic Mode Density In Silver Nanodisks And Far Field Focusing Of Light By Coupled Plasmonic Nanorings, Longyu Hu

All Dissertations

During the past twenty years, plasmonic nanostructures have evolved as one of the most promising candidates for applications in miniaturized optical and electronic devices, bio-sensors and photonic circuits, etc. Silver nanoparticles can interact with light more strongly than any known materials with similar dimensions, and support tunable optical properties based on their size, shape and sounding medium, which are more stable than optical properties of traditional pigments and dyes.

Thanks to the recent progress in the synthesis of various silver nanoparticles with different shape and sizes, which has opened doors to the exciting research field of plasmonics. However, silver nanoparticles …

The Wright Message, 2017-2018, University Of Northern Iowa. Department Of Mathematics.

The Wright Message

Inside this issue:

-- New Faculty
--Faculty Spotlight
--Around Wright Hall
--Interview
--Alumni Spotlight
--Hari Shankar Lecture
--Wright Hall Centenary
--News from the CTLM
--Student Spotlights
--Mathematical Ideas Conference
--Donor Spotlight
--Retiring Faculty
--Classrooms Named in Honor of Faculty
--Contributions to an Account – Recognition
--Department Funds

Nurturing Student Scientists As People Of Faith, Nicole C. Bouvier-Brown

Jesuit Higher Education: A Journal

The Loyola Marymount University (LMU) campus community fosters the interplay between religious faith and scientific reason. Not only is this evident by honoring scientists in the stained-glass windows of Sacred Heart Chapel, but the culture invigorates a disproportionate number of science students to actively engage with the faith community. This integration might seem counter to society’s norms, but it is well aligned with the teachings of the Catholic Church and Jesuit tradition. Jesuit universities, in particular, have a unique role to play in fostering the mutual enrichment between faith and scientific reason. Education should be used to bridge the misunderstandings …

Manufacturing And Instrumentation Of An Open End Compressed Air Shock Tube, Josue O. Ruiz

Master's Theses

Shock tubes have been used extensively to study shock wave structures and high speed flow features. The purpose of constructing this open end shock tube was to have the ability to produce shock waves in a laboratory setting but also understand the exit flow coming out which can be applied to future studies that are beyond the scope of this work. This undertaking would require that an open end shock tube be built and instrumented with PCB Integrated Circuit Piezoelectric (ICP) Pressure Sensor Model 113B24 that would then be connected to a PCB Model 482C05 Signal Conditioner with the purpose …

Philosophy In Our Core, Patrick Tully Ph.D.

Jesuit Higher Education: A Journal

The Jesuit (and Catholic) educational tradition is characterized by a number of identity-conferring basic positions that are incompatible with correlative positions on offer in the popular culture. Some of these fundamental differences between the tradition and the culture are philosophical in nature in that they bear on questions of moral truth and philosophical anthropology. Institutions of higher education committed to forming their students in light of these basic and counter-cultural beliefs must ensure that the incompatible cultural alternatives are carefully examined and the reasonableness of the Ignatian (Catholic) alternatives carefully explored. The discipline Philosophy plays an irreplaceable role in this …

Development Of Innate Immunity During In Vitro Differentiation Of Mouse Embryonic Stem Cells, William D'Angelo

Dissertations

Embryonic stem cells (ESCs) hold enormous promise for the goals of regenerative medicine and tissue engineering, and extraordinary progress has been made in defining conditions for differentiation to desired cell types. However, an often overlooked aspect of ESC biology is innate immunity, the ability of cells to detect and respond to pathogens and inflammatory cytokines. A number of recent studies by our lab and others have established that ESCs and other types of pluripotent cells from both mice and humans do not mount typical immune responses to viral or bacterial stimuli. There are also indications that various cell types differentiated …

Ecological And Oceanographic Influences On Leatherback Turtle Behavior And Scyphozoan Jellyfish Distributions In The Gulf Of Mexico, Katrina Aleksa

Dissertations

Leatherback turtles (Dermochelys coriacea) are a wide-ranging, oceanic species that feed exclusively on gelatinous zooplankton. Leatherback have been spotted in the Gulf of Mexico (GoM) for several decades and consistently had a high level of interactions with longline fisheries. However, no quantitative studies have been performed to address the spatiotemporal distribution of these turtles in the GoM. This research determines 1) leatherback movements and high-use areas in the GoM, 2) their association with oceanographic features, 3) the distribution and density of two abundant medusae in the northern GoM and any association with biophysical parameters, and 4) the body …

An Examination Of Subtypes Of Posttraumatic Stress Disorder Utilizing Latent Profile And Taxometric Analyses, Joseph Finn

Dissertations

Prior studies examining PTSD subtypes have yielded mixed results, likely stemming in part from the use of divergent samples and measurement techniques. This study aimed to expand upon these findings by utilizing a large nationally-representative sample in combination with sophisticated statistical analyses. Utilizing a sample of 2496 adults with a diagnosis of PTSD, latent profile analysis was used to determine the optimal number and composition of latent classes of individuals diagnosed with PTSD, and then taxometric analysis was utilized to determine whether these classes differed not only in degree, but in kind.

Finally, class relationships with a number of external …

Tamarind Seed Polysaccharides And Their Nanocomposites For Drug Delivery: An Economical, Eco-Friendly And Novel Approach, Rashmirekha Sahoo, Soumendra Sahoo, Saeed Azizi

Manipal Journal of Medical Sciences

The biomedical engineering field has shown to foster innovation in nanotechnology. Facilitated by engineering and biotechnology, biomedical engineering has the potential to significantly influence the pharmaceutical industry. Advancements in nanotechnology can resolve current issues with drug delivery techniques by increasing efficacy or improving patient safety and patient compliance. Natural polysaccharide-based biomaterials are proving to be important in creating innovative drug delivery devices. Biodegradability and biological activity that can be controlled are important properties of polysaccharides. The tamarind industry has various by-products, including the tamarind seed. Tamarind kernel powder (TKP), also known as the decorticated flour of tamarind has been explored …

Policy Implications: An Analysis Of Intercountry Adoption In Relation To Nationalism, Victoria Szczechowski

Honors Theses

This research seeks to answer the question: Does level of nationalist sentiment expressed within a country affect the restrictiveness of the country’s intercountry adoption policy? Current literature has examined the influence of the level of nationalism expressed in a country on adoptive parents in choosing from which country to adopt; however, no study has examined the link between nationalism and country-specific intercountry adoption policy. The variable of nationalist sentiment warrants study, for the Hague Convention posits that intercountry adoption is a valid option only if “a suitable family cannot be found in his or her [the adoptable child’s] State of …

Fluorescence-Reported Allelic Exchange Mutagenesis Reveals A Role For Chlamydia Trachomatis Tmea In Invasion That Is Independent Of Host Ahnak, M. J. Mckuen, Konrad E. Mueller, Y. S. Bae, Kenneth A. Fields

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Development of approaches to genetically manipulate Chlamydia is fostering important advances in understanding pathogenesis. Fluorescence-reported allelic exchange mutagenesis (FRAEM) now enables the complete deletion of specific genes in C. trachomatis L2. We have leveraged this technology to delete the coding sequences for a known type III effector. The evidence provided here indicates that CT694/CTL0063 is a virulence protein involved in chlamydial invasion. Based on our findings, we designate the gene product corresponding to ct694-ctl0063 translocated membrane-associated effector A (TmeA). Deletion of tmeA did not impact development of intracellular chlamydiae. However, the absence of TmeA manifested as a decrease in infectivity …